Result of FASTA (omim) for pF1KB3419
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB3419, 800 aa
  1>>>pF1KB3419 800 - 800 aa - 800 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 14.0338+/-0.000578; mu= -22.9370+/- 0.036
 mean_var=714.0750+/-161.402, 0's: 0 Z-trim(116.1): 1306  B-trim: 1499 in 1/59
 Lambda= 0.047996
 statistics sampled from 25245 (27004) to 25245 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.657), E-opt: 0.2 (0.317), width:  16
 Scan time: 13.340

The best scores are:                                      opt bits E(85289)
NP_057737 (OMIM: 609479,616890) mitogen-activated  ( 800) 5398 390.6 1.4e-107
XP_005246697 (OMIM: 609479,616890) PREDICTED: mito ( 800) 5398 390.6 1.4e-107
XP_016859813 (OMIM: 609479,616890) PREDICTED: mito ( 455) 2221 170.4 1.6e-41
XP_016859812 (OMIM: 609479,616890) PREDICTED: mito ( 455) 2221 170.4 1.6e-41
NP_598407 (OMIM: 609479,616890) mitogen-activated  ( 455) 2221 170.4 1.6e-41
XP_005269197 (OMIM: 600447) PREDICTED: mitogen-act ( 453)  739 67.8 1.2e-10
XP_016875445 (OMIM: 600447) PREDICTED: mitogen-act ( 859)  739 68.1 1.9e-10
NP_006292 (OMIM: 600447) mitogen-activated protein ( 859)  739 68.1 1.9e-10
NP_001180440 (OMIM: 600447) mitogen-activated prot ( 892)  739 68.1 1.9e-10
XP_005269195 (OMIM: 600447) PREDICTED: mitogen-act ( 892)  739 68.1 1.9e-10
XP_006719651 (OMIM: 600447) PREDICTED: mitogen-act ( 892)  739 68.1 1.9e-10
XP_011537027 (OMIM: 600447) PREDICTED: mitogen-act ( 892)  739 68.1 1.9e-10
XP_016862946 (OMIM: 604915) PREDICTED: mitogen-act ( 817)  714 66.3   6e-10
XP_016862945 (OMIM: 604915) PREDICTED: mitogen-act ( 966)  714 66.4 6.8e-10
NP_001229243 (OMIM: 604915) mitogen-activated prot ( 966)  714 66.4 6.8e-10
NP_004712 (OMIM: 604915) mitogen-activated protein ( 966)  714 66.4 6.8e-10
XP_011511612 (OMIM: 604915) PREDICTED: mitogen-act ( 966)  714 66.4 6.8e-10
XP_005267740 (OMIM: 600136) PREDICTED: mitogen-act (1081)  704 65.8 1.2e-09
NP_001271159 (OMIM: 600136) mitogen-activated prot (1104)  704 65.8 1.2e-09
NP_149132 (OMIM: 600136) mitogen-activated protein (1118)  704 65.8 1.2e-09
XP_011535090 (OMIM: 600136) PREDICTED: mitogen-act (1166)  704 65.8 1.2e-09
NP_002410 (OMIM: 600050) mitogen-activated protein ( 847)  693 64.9 1.7e-09
NP_002437 (OMIM: 600137) mitogen-activated protein ( 954)  691 64.8   2e-09
XP_011525284 (OMIM: 600137) PREDICTED: mitogen-act ( 860)  662 62.7 7.6e-09
XP_011525283 (OMIM: 600137) PREDICTED: mitogen-act ( 962)  662 62.8 8.2e-09
NP_001229246 (OMIM: 604915) mitogen-activated prot ( 759)  624 60.1 4.3e-08
XP_011542607 (OMIM: 614793) PREDICTED: mitogen-act ( 905)  601 58.5 1.5e-07
NP_115811 (OMIM: 614793) mitogen-activated protein (1036)  601 58.6 1.6e-07
XP_016862948 (OMIM: 604915) PREDICTED: mitogen-act ( 734)  592 57.8   2e-07
XP_016862947 (OMIM: 604915) PREDICTED: mitogen-act ( 734)  592 57.8   2e-07
NP_663306 (OMIM: 157800,602614,617137) mitogen-act ( 491)  571 56.2 4.1e-07
NP_663305 (OMIM: 157800,602614,617137) mitogen-act ( 518)  571 56.2 4.3e-07
NP_003179 (OMIM: 157800,602614,617137) mitogen-act ( 579)  571 56.3 4.6e-07
NP_663304 (OMIM: 157800,602614,617137) mitogen-act ( 606)  571 56.3 4.7e-07
NP_001161711 (OMIM: 164690) Abelson tyrosine-prote (1043)  559 55.7 1.2e-06
NP_001161710 (OMIM: 164690) Abelson tyrosine-prote (1058)  559 55.7 1.2e-06
NP_001129472 (OMIM: 164690) Abelson tyrosine-prote (1064)  559 55.7 1.2e-06
NP_001161709 (OMIM: 164690) Abelson tyrosine-prote (1079)  559 55.7 1.2e-06
XP_005245145 (OMIM: 164690) PREDICTED: Abelson tyr (1146)  559 55.7 1.3e-06
NP_001161708 (OMIM: 164690) Abelson tyrosine-prote (1161)  559 55.8 1.3e-06
NP_005149 (OMIM: 164690) Abelson tyrosine-protein  (1167)  559 55.8 1.3e-06
XP_016856524 (OMIM: 164690) PREDICTED: Abelson tyr (1182)  559 55.8 1.3e-06
NP_009298 (OMIM: 164690) Abelson tyrosine-protein  (1182)  559 55.8 1.3e-06
NP_001129473 (OMIM: 164690) Abelson tyrosine-prote ( 542)  528 53.2 3.5e-06
NP_005148 (OMIM: 189980) tyrosine-protein kinase A (1130)  535 54.1   4e-06
NP_009297 (OMIM: 189980) tyrosine-protein kinase A (1149)  535 54.1 4.1e-06
XP_016866143 (OMIM: 137025) PREDICTED: tyrosine-pr ( 537)  499 51.2 1.4e-05
XP_016866141 (OMIM: 137025) PREDICTED: tyrosine-pr ( 537)  499 51.2 1.4e-05
XP_016866139 (OMIM: 137025) PREDICTED: tyrosine-pr ( 537)  499 51.2 1.4e-05
XP_016866142 (OMIM: 137025) PREDICTED: tyrosine-pr ( 537)  499 51.2 1.4e-05


>>NP_057737 (OMIM: 609479,616890) mitogen-activated prot  (800 aa)
 initn: 5398 init1: 5398 opt: 5398  Z-score: 2052.5  bits: 390.6 E(85289): 1.4e-107
Smith-Waterman score: 5398; 99.9% identity (99.9% similar) in 800 aa overlap (1-800:1-800)

               10        20        30        40        50        60
pF1KB3 MSSLGASFVQIKFDDLQFFENCGGGSFGSVYRAKWISQDKEVAVKKLLKIEKEAEILSVL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 MSSLGASFVQIKFDDLQFFENCGGGSFGSVYRAKWISQDKEVAVKKLLKIEKEAEILSVL
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB3 SHRNIIQFYGVILEPPNYGIVTEYASLGSLYDYINSNRSEEMDMDHIMTWATDVAKGMHY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 SHRNIIQFYGVILEPPNYGIVTEYASLGSLYDYINSNRSEEMDMDHIMTWATDVAKGMHY
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB3 LHMEAPVKVIHRDLKSRNVVIAADGVLKICDFGASRFHNHTTHMSLVGTFPWMAPEVIQS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 LHMEAPVKVIHRDLKSRNVVIAADGVLKICDFGASRFHNHTTHMSLVGTFPWMAPEVIQS
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB3 LPVSETCDTYSYGVVLWEMLTREVPFKGLEGLQVAWLVVEKNERLTIPSSCPRSFAELLH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 LPVSETCDTYSYGVVLWEMLTREVPFKGLEGLQVAWLVVEKNERLTIPSSCPRSFAELLH
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB3 QCWEADAKKRPSFKQIISILESMSNDTSLPDKCNSFLHNKAEWRCEIEATLERLKKLERD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 QCWEADAKKRPSFKQIISILESMSNDTSLPDKCNSFLHNKAEWRCEIEATLERLKKLERD
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB3 LSFKEQELKERERRLKMWEQKLTEQSNTPLLPSFEIGAWTEDDVYCWVQQLVRKGDSSAE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 LSFKEQELKERERRLKMWEQKLTEQSNTPLLPSFEIGAWTEDDVYCWVQQLVRKGDSSAE
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB3 MSVYASLFKENNITGKRLLLLEEEDLKDMGIVSKGHIIHFKSAIEKLTHDYINLFHFPPL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 MSVYASLFKENNITGKRLLLLEEEDLKDMGIVSKGHIIHFKSAIEKLTHDYINLFHFPPL
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KB3 IKDSGGEPEENEEKIVNLELVFGFHLKPGTGPQDCKWKMYMEMDGDEIAITYIKDVTFNT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 IKDSGGEPEENEEKIVNLELVFGFHLKPGTGPQDCKWKMYMEMDGDEIAITYIKDVTFNT
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KB3 NLPDAEILKMTKPPFVMEKWIVGIAKSQTVECTVTYESDVRTPKSTKHVHSIQWSRTKPQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 NLPDAEILKMTKPPFVMEKWIVGIAKSQTVECTVTYESDVRTPKSTKHVHSIQWSRTKPQ
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KB3 DEVKAVQLAIQTLFTNSDGNPGSRSDSSADCQWLDTLRMRQIASNTSLQRSQSNPILGSP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 DEVKAVQLAIQTLFTNSDGNPGSRSDSSADCQWLDTLRMRQIASNTSLQRSQSNPILGSP
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KB3 FFSHFDGQDSYAAAVRRPQVPIKYQQITPVNQSRSSSPTQYGLTKNFSSLHLNSRDSGFS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 FFSHFDGQDSYAAAVRRPQVPIKYQQITPVNQSRSSSPTQYGLTKNFSSLHLNSRDSGFS
              610       620       630       640       650       660

              670       680       690       700       710       720
pF1KB3 SGNTDTSSERGRYSDRSRNKYGRGSISLNSSPRGRYSGKSQHSTPSRGRYPGKFYRVSQS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 SGNTDTSSERGRYSDRSRNKYGRGSISLNSSPRGRYSGKSQHSTPSRGRYPGKFYRVSQS
              670       680       690       700       710       720

              730       740       750       760       770       780
pF1KB3 ALNPHQSPDFKRSPRDLHQPNTIPGMPLHPETDSRASEEDSKVSEGGWTKVEYRKKPHRP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 ALNPHQSPDFKRSPRDLHQPNTIPGMPLHPETDSRASEEDSKVSEGGWTKVEYRKKPHRP
              730       740       750       760       770       780

              790       800
pF1KB3 SPATTNKERARGDHRGWRNF
       ::: ::::::::::::::::
NP_057 SPAKTNKERARGDHRGWRNF
              790       800

>>XP_005246697 (OMIM: 609479,616890) PREDICTED: mitogen-  (800 aa)
 initn: 5398 init1: 5398 opt: 5398  Z-score: 2052.5  bits: 390.6 E(85289): 1.4e-107
Smith-Waterman score: 5398; 99.9% identity (99.9% similar) in 800 aa overlap (1-800:1-800)

               10        20        30        40        50        60
pF1KB3 MSSLGASFVQIKFDDLQFFENCGGGSFGSVYRAKWISQDKEVAVKKLLKIEKEAEILSVL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MSSLGASFVQIKFDDLQFFENCGGGSFGSVYRAKWISQDKEVAVKKLLKIEKEAEILSVL
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB3 SHRNIIQFYGVILEPPNYGIVTEYASLGSLYDYINSNRSEEMDMDHIMTWATDVAKGMHY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SHRNIIQFYGVILEPPNYGIVTEYASLGSLYDYINSNRSEEMDMDHIMTWATDVAKGMHY
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB3 LHMEAPVKVIHRDLKSRNVVIAADGVLKICDFGASRFHNHTTHMSLVGTFPWMAPEVIQS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LHMEAPVKVIHRDLKSRNVVIAADGVLKICDFGASRFHNHTTHMSLVGTFPWMAPEVIQS
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB3 LPVSETCDTYSYGVVLWEMLTREVPFKGLEGLQVAWLVVEKNERLTIPSSCPRSFAELLH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LPVSETCDTYSYGVVLWEMLTREVPFKGLEGLQVAWLVVEKNERLTIPSSCPRSFAELLH
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB3 QCWEADAKKRPSFKQIISILESMSNDTSLPDKCNSFLHNKAEWRCEIEATLERLKKLERD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QCWEADAKKRPSFKQIISILESMSNDTSLPDKCNSFLHNKAEWRCEIEATLERLKKLERD
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB3 LSFKEQELKERERRLKMWEQKLTEQSNTPLLPSFEIGAWTEDDVYCWVQQLVRKGDSSAE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LSFKEQELKERERRLKMWEQKLTEQSNTPLLPSFEIGAWTEDDVYCWVQQLVRKGDSSAE
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB3 MSVYASLFKENNITGKRLLLLEEEDLKDMGIVSKGHIIHFKSAIEKLTHDYINLFHFPPL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MSVYASLFKENNITGKRLLLLEEEDLKDMGIVSKGHIIHFKSAIEKLTHDYINLFHFPPL
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KB3 IKDSGGEPEENEEKIVNLELVFGFHLKPGTGPQDCKWKMYMEMDGDEIAITYIKDVTFNT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 IKDSGGEPEENEEKIVNLELVFGFHLKPGTGPQDCKWKMYMEMDGDEIAITYIKDVTFNT
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KB3 NLPDAEILKMTKPPFVMEKWIVGIAKSQTVECTVTYESDVRTPKSTKHVHSIQWSRTKPQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 NLPDAEILKMTKPPFVMEKWIVGIAKSQTVECTVTYESDVRTPKSTKHVHSIQWSRTKPQ
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KB3 DEVKAVQLAIQTLFTNSDGNPGSRSDSSADCQWLDTLRMRQIASNTSLQRSQSNPILGSP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DEVKAVQLAIQTLFTNSDGNPGSRSDSSADCQWLDTLRMRQIASNTSLQRSQSNPILGSP
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KB3 FFSHFDGQDSYAAAVRRPQVPIKYQQITPVNQSRSSSPTQYGLTKNFSSLHLNSRDSGFS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 FFSHFDGQDSYAAAVRRPQVPIKYQQITPVNQSRSSSPTQYGLTKNFSSLHLNSRDSGFS
              610       620       630       640       650       660

              670       680       690       700       710       720
pF1KB3 SGNTDTSSERGRYSDRSRNKYGRGSISLNSSPRGRYSGKSQHSTPSRGRYPGKFYRVSQS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SGNTDTSSERGRYSDRSRNKYGRGSISLNSSPRGRYSGKSQHSTPSRGRYPGKFYRVSQS
              670       680       690       700       710       720

              730       740       750       760       770       780
pF1KB3 ALNPHQSPDFKRSPRDLHQPNTIPGMPLHPETDSRASEEDSKVSEGGWTKVEYRKKPHRP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ALNPHQSPDFKRSPRDLHQPNTIPGMPLHPETDSRASEEDSKVSEGGWTKVEYRKKPHRP
              730       740       750       760       770       780

              790       800
pF1KB3 SPATTNKERARGDHRGWRNF
       ::: ::::::::::::::::
XP_005 SPAKTNKERARGDHRGWRNF
              790       800

>>XP_016859813 (OMIM: 609479,616890) PREDICTED: mitogen-  (455 aa)
 initn: 2215 init1: 2215 opt: 2221  Z-score: 866.6  bits: 170.4 E(85289): 1.6e-41
Smith-Waterman score: 2226; 78.2% identity (86.6% similar) in 455 aa overlap (1-454:1-441)

               10        20        30        40        50        60
pF1KB3 MSSLGASFVQIKFDDLQFFENCGGGSFGSVYRAKWISQDKEVAVKKLLKIEKEAEILSVL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MSSLGASFVQIKFDDLQFFENCGGGSFGSVYRAKWISQDKEVAVKKLLKIEKEAEILSVL
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB3 SHRNIIQFYGVILEPPNYGIVTEYASLGSLYDYINSNRSEEMDMDHIMTWATDVAKGMHY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SHRNIIQFYGVILEPPNYGIVTEYASLGSLYDYINSNRSEEMDMDHIMTWATDVAKGMHY
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB3 LHMEAPVKVIHRDLKSRNVVIAADGVLKICDFGASRFHNHTTHMSLVGTFPWMAPEVIQS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LHMEAPVKVIHRDLKSRNVVIAADGVLKICDFGASRFHNHTTHMSLVGTFPWMAPEVIQS
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB3 LPVSETCDTYSYGVVLWEMLTREVPFKGLEGLQVAWLVVEKNERLTIPSSCPRSFAELLH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LPVSETCDTYSYGVVLWEMLTREVPFKGLEGLQVAWLVVEKNERLTIPSSCPRSFAELLH
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB3 QCWEADAKKRPSFKQIISILESMSNDTSLPDKCNSFLHNKAEWRCEIEATLERLKKLERD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QCWEADAKKRPSFKQIISILESMSNDTSLPDKCNSFLHNKAEWRCEIEATLERLKKLERD
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB3 LSFKEQELKERERRLKMWEQKLTEQSNTPLLPSFEIGAWTEDDVYCWVQQLVRKGDSSAE
       :::::::::::::::::::::::::::::::  . ..:   .. :   .    . ..:::
XP_016 LSFKEQELKERERRLKMWEQKLTEQSNTPLL--LPLAARMSEESYFESKT---EESNSAE
              310       320       330         340          350     

              370       380       390       400       410       420
pF1KB3 MSVYASLFKENNITGKRLLLLEEEDLKDMGIVSKGHIIHFKSAIEKLTHDYINLFHFPPL
       ::   ..   .:  :. .    . .:. : ... : :. ...:   . :. ...      
XP_016 MS--CQITATSNGEGHGM----NPSLQAMMLMGFGDIFSMNKA-GAVMHSGMQINM--QA
           360       370           380       390        400        

              430       440        450       460       470         
pF1KB3 IKDSGGEPEENEEKIVNLELVFG-FHLKPGTGPQDCKWKMYMEMDGDEIAITYIKDVTFN
        ..:.    . . : ::. : :. : :. :   .:                         
XP_016 KQNSSKTTSKRRGKKVNMALGFSDFDLSEGDDDDDDDGEEEDNDMDNSE           
        410       420       430       440       450                

     480       490       500       510       520       530         
pF1KB3 TNLPDAEILKMTKPPFVMEKWIVGIAKSQTVECTVTYESDVRTPKSTKHVHSIQWSRTKP

>>XP_016859812 (OMIM: 609479,616890) PREDICTED: mitogen-  (455 aa)
 initn: 2215 init1: 2215 opt: 2221  Z-score: 866.6  bits: 170.4 E(85289): 1.6e-41
Smith-Waterman score: 2226; 78.2% identity (86.6% similar) in 455 aa overlap (1-454:1-441)

               10        20        30        40        50        60
pF1KB3 MSSLGASFVQIKFDDLQFFENCGGGSFGSVYRAKWISQDKEVAVKKLLKIEKEAEILSVL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MSSLGASFVQIKFDDLQFFENCGGGSFGSVYRAKWISQDKEVAVKKLLKIEKEAEILSVL
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB3 SHRNIIQFYGVILEPPNYGIVTEYASLGSLYDYINSNRSEEMDMDHIMTWATDVAKGMHY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SHRNIIQFYGVILEPPNYGIVTEYASLGSLYDYINSNRSEEMDMDHIMTWATDVAKGMHY
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB3 LHMEAPVKVIHRDLKSRNVVIAADGVLKICDFGASRFHNHTTHMSLVGTFPWMAPEVIQS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LHMEAPVKVIHRDLKSRNVVIAADGVLKICDFGASRFHNHTTHMSLVGTFPWMAPEVIQS
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB3 LPVSETCDTYSYGVVLWEMLTREVPFKGLEGLQVAWLVVEKNERLTIPSSCPRSFAELLH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LPVSETCDTYSYGVVLWEMLTREVPFKGLEGLQVAWLVVEKNERLTIPSSCPRSFAELLH
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB3 QCWEADAKKRPSFKQIISILESMSNDTSLPDKCNSFLHNKAEWRCEIEATLERLKKLERD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QCWEADAKKRPSFKQIISILESMSNDTSLPDKCNSFLHNKAEWRCEIEATLERLKKLERD
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB3 LSFKEQELKERERRLKMWEQKLTEQSNTPLLPSFEIGAWTEDDVYCWVQQLVRKGDSSAE
       :::::::::::::::::::::::::::::::  . ..:   .. :   .    . ..:::
XP_016 LSFKEQELKERERRLKMWEQKLTEQSNTPLL--LPLAARMSEESYFESKT---EESNSAE
              310       320       330         340          350     

              370       380       390       400       410       420
pF1KB3 MSVYASLFKENNITGKRLLLLEEEDLKDMGIVSKGHIIHFKSAIEKLTHDYINLFHFPPL
       ::   ..   .:  :. .    . .:. : ... : :. ...:   . :. ...      
XP_016 MS--CQITATSNGEGHGM----NPSLQAMMLMGFGDIFSMNKA-GAVMHSGMQINM--QA
           360       370           380       390        400        

              430       440        450       460       470         
pF1KB3 IKDSGGEPEENEEKIVNLELVFG-FHLKPGTGPQDCKWKMYMEMDGDEIAITYIKDVTFN
        ..:.    . . : ::. : :. : :. :   .:                         
XP_016 KQNSSKTTSKRRGKKVNMALGFSDFDLSEGDDDDDDDGEEEDNDMDNSE           
        410       420       430       440       450                

     480       490       500       510       520       530         
pF1KB3 TNLPDAEILKMTKPPFVMEKWIVGIAKSQTVECTVTYESDVRTPKSTKHVHSIQWSRTKP

>>NP_598407 (OMIM: 609479,616890) mitogen-activated prot  (455 aa)
 initn: 2215 init1: 2215 opt: 2221  Z-score: 866.6  bits: 170.4 E(85289): 1.6e-41
Smith-Waterman score: 2226; 78.2% identity (86.6% similar) in 455 aa overlap (1-454:1-441)

               10        20        30        40        50        60
pF1KB3 MSSLGASFVQIKFDDLQFFENCGGGSFGSVYRAKWISQDKEVAVKKLLKIEKEAEILSVL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_598 MSSLGASFVQIKFDDLQFFENCGGGSFGSVYRAKWISQDKEVAVKKLLKIEKEAEILSVL
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB3 SHRNIIQFYGVILEPPNYGIVTEYASLGSLYDYINSNRSEEMDMDHIMTWATDVAKGMHY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_598 SHRNIIQFYGVILEPPNYGIVTEYASLGSLYDYINSNRSEEMDMDHIMTWATDVAKGMHY
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB3 LHMEAPVKVIHRDLKSRNVVIAADGVLKICDFGASRFHNHTTHMSLVGTFPWMAPEVIQS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_598 LHMEAPVKVIHRDLKSRNVVIAADGVLKICDFGASRFHNHTTHMSLVGTFPWMAPEVIQS
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB3 LPVSETCDTYSYGVVLWEMLTREVPFKGLEGLQVAWLVVEKNERLTIPSSCPRSFAELLH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_598 LPVSETCDTYSYGVVLWEMLTREVPFKGLEGLQVAWLVVEKNERLTIPSSCPRSFAELLH
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB3 QCWEADAKKRPSFKQIISILESMSNDTSLPDKCNSFLHNKAEWRCEIEATLERLKKLERD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_598 QCWEADAKKRPSFKQIISILESMSNDTSLPDKCNSFLHNKAEWRCEIEATLERLKKLERD
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB3 LSFKEQELKERERRLKMWEQKLTEQSNTPLLPSFEIGAWTEDDVYCWVQQLVRKGDSSAE
       :::::::::::::::::::::::::::::::  . ..:   .. :   .    . ..:::
NP_598 LSFKEQELKERERRLKMWEQKLTEQSNTPLL--LPLAARMSEESYFESKT---EESNSAE
              310       320       330         340          350     

              370       380       390       400       410       420
pF1KB3 MSVYASLFKENNITGKRLLLLEEEDLKDMGIVSKGHIIHFKSAIEKLTHDYINLFHFPPL
       ::   ..   .:  :. .    . .:. : ... : :. ...:   . :. ...      
NP_598 MS--CQITATSNGEGHGM----NPSLQAMMLMGFGDIFSMNKA-GAVMHSGMQINM--QA
           360       370           380       390        400        

              430       440        450       460       470         
pF1KB3 IKDSGGEPEENEEKIVNLELVFG-FHLKPGTGPQDCKWKMYMEMDGDEIAITYIKDVTFN
        ..:.    . . : ::. : :. : :. :   .:                         
NP_598 KQNSSKTTSKRRGKKVNMALGFSDFDLSEGDDDDDDDGEEEDNDMDNSE           
        410       420       430       440       450                

     480       490       500       510       520       530         
pF1KB3 TNLPDAEILKMTKPPFVMEKWIVGIAKSQTVECTVTYESDVRTPKSTKHVHSIQWSRTKP

>>XP_005269197 (OMIM: 600447) PREDICTED: mitogen-activat  (453 aa)
 initn: 492 init1: 358 opt: 739  Z-score: 312.0  bits: 67.8 E(85289): 1.2e-10
Smith-Waterman score: 739; 39.9% identity (70.5% similar) in 308 aa overlap (10-313:152-449)

                                    10        20        30         
pF1KB3                      MSSLGASFVQIKFDDLQFFENCGGGSFGSVYRAKWISQD
                                     .. :...  ..  :.:. :.:. ...  . 
XP_005 EGLFGCLRPVWTMIGKAYSTEHKQQQEDLWEVPFEEILDLQWVGSGAQGAVFLGRF--HG
             130       140       150       160       170           

      40        50          60        70        80        90       
pF1KB3 KEVAVKKLLKIEKEAEI--LSVLSHRNIIQFYGVILEPPNYGIVTEYASLGSLYDYINSN
       .::::::.  . ::..:  :  :.: ::: : ::  . : : :. :. . :.::. . ..
XP_005 EEVAVKKVRDL-KETDIKHLRKLKHPNIITFKGVCTQAPCYCILMEFCAQGQLYEVLRAG
     180       190        200       210       220       230        

       100       110       120       130       140       150       
pF1KB3 RSEEMDMDHIMTWATDVAKGMHYLHMEAPVKVIHRDLKSRNVVIAADGVLKICDFGASR-
       :    ..  .. :.  .: ::.:::..   :.::::::: :..:. : :.:: :::.:. 
XP_005 RPVTPSL--LVDWSMGIAGGMNYLHLH---KIIHRDLKSPNMLITYDDVVKISDFGTSKE
      240         250       260          270       280       290   

        160       170       180       190       200       210      
pF1KB3 FHNHTTHMSLVGTFPWMAPEVIQSLPVSETCDTYSYGVVLWEMLTREVPFKGLEGLQVAW
       . ...:.::..::  :::::::.. ::::  : .:.::::::.:: :.:.: ...  . :
XP_005 LSDKSTKMSFAGTVAWMAPEVIRNEPVSEKVDIWSFGVVLWELLTGEIPYKDVDSSAIIW
           300       310       320       330       340       350   

        220       230       240       250       260        270     
pF1KB3 LVVEKNERLTIPSSCPRSFAELLHQCWEADAKKRPSFKQIISILESMSNDT-SLPDKCNS
        :  .. .: .::::: .:  ::.:::..  ..::::.::.  :.  : :. : :..  .
XP_005 GVGSNSLHLPVPSSCPDGFKILLRQCWNSKPRNRPSFRQILLHLDIASADVLSTPQE--T
           360       370       380       390       400       410   

         280       290       300       310       320       330     
pF1KB3 FLHNKAEWRCEIEATLERLKKLERDLSFKEQELKERERRLKMWEQKLTEQSNTPLLPSFE
       .....:::: :..  .:..:.    :   :.::  :.:                      
XP_005 YFKSQAEWREEVKLHFEKIKSEGTCLHRLEEELVMRRREELR                  
             420       430       440       450                     

         340       350       360       370       380       390     
pF1KB3 IGAWTEDDVYCWVQQLVRKGDSSAEMSVYASLFKENNITGKRLLLLEEEDLKDMGIVSKG

>>XP_016875445 (OMIM: 600447) PREDICTED: mitogen-activat  (859 aa)
 initn: 432 init1: 376 opt: 739  Z-score: 308.6  bits: 68.1 E(85289): 1.9e-10
Smith-Waterman score: 739; 39.9% identity (70.5% similar) in 308 aa overlap (10-313:119-416)

                                    10        20        30         
pF1KB3                      MSSLGASFVQIKFDDLQFFENCGGGSFGSVYRAKWISQD
                                     .. :...  ..  :.:. :.:. ...  . 
XP_016 EGLFGCLRPVWTMIGKAYSTEHKQQQEDLWEVPFEEILDLQWVGSGAQGAVFLGRF--HG
       90       100       110       120       130       140        

      40        50          60        70        80        90       
pF1KB3 KEVAVKKLLKIEKEAEI--LSVLSHRNIIQFYGVILEPPNYGIVTEYASLGSLYDYINSN
       .::::::.  . ::..:  :  :.: ::: : ::  . : : :. :. . :.::. . ..
XP_016 EEVAVKKVRDL-KETDIKHLRKLKHPNIITFKGVCTQAPCYCILMEFCAQGQLYEVLRAG
        150        160       170       180       190       200     

       100       110       120       130       140       150       
pF1KB3 RSEEMDMDHIMTWATDVAKGMHYLHMEAPVKVIHRDLKSRNVVIAADGVLKICDFGASR-
       :    ..  .. :.  .: ::.:::..   :.::::::: :..:. : :.:: :::.:. 
XP_016 RPVTPSL--LVDWSMGIAGGMNYLHLH---KIIHRDLKSPNMLITYDDVVKISDFGTSKE
         210         220       230          240       250       260

        160       170       180       190       200       210      
pF1KB3 FHNHTTHMSLVGTFPWMAPEVIQSLPVSETCDTYSYGVVLWEMLTREVPFKGLEGLQVAW
       . ...:.::..::  :::::::.. ::::  : .:.::::::.:: :.:.: ...  . :
XP_016 LSDKSTKMSFAGTVAWMAPEVIRNEPVSEKVDIWSFGVVLWELLTGEIPYKDVDSSAIIW
              270       280       290       300       310       320

        220       230       240       250       260        270     
pF1KB3 LVVEKNERLTIPSSCPRSFAELLHQCWEADAKKRPSFKQIISILESMSNDT-SLPDKCNS
        :  .. .: .::::: .:  ::.:::..  ..::::.::.  :.  : :. : :..  .
XP_016 GVGSNSLHLPVPSSCPDGFKILLRQCWNSKPRNRPSFRQILLHLDIASADVLSTPQE--T
              330       340       350       360       370          

         280       290       300       310       320       330     
pF1KB3 FLHNKAEWRCEIEATLERLKKLERDLSFKEQELKERERRLKMWEQKLTEQSNTPLLPSFE
       .....:::: :..  .:..:.    :   :.::  :.:                      
XP_016 YFKSQAEWREEVKLHFEKIKSEGTCLHRLEEELVMRRREELRHALDIREHYERKLERANN
      380       390       400       410       420       430        

         340       350       360       370       380       390     
pF1KB3 IGAWTEDDVYCWVQQLVRKGDSSAEMSVYASLFKENNITGKRLLLLEEEDLKDMGIVSKG
                                                                   
XP_016 LYMELNALMLQLELKERELLRREQALERRCPGLLKPHPSRGLLHGNTMEKLIKKRNVPQK
      440       450       460       470       480       490        

>>NP_006292 (OMIM: 600447) mitogen-activated protein kin  (859 aa)
 initn: 432 init1: 376 opt: 739  Z-score: 308.6  bits: 68.1 E(85289): 1.9e-10
Smith-Waterman score: 739; 39.9% identity (70.5% similar) in 308 aa overlap (10-313:119-416)

                                    10        20        30         
pF1KB3                      MSSLGASFVQIKFDDLQFFENCGGGSFGSVYRAKWISQD
                                     .. :...  ..  :.:. :.:. ...  . 
NP_006 EGLFGCLRPVWTMIGKAYSTEHKQQQEDLWEVPFEEILDLQWVGSGAQGAVFLGRF--HG
       90       100       110       120       130       140        

      40        50          60        70        80        90       
pF1KB3 KEVAVKKLLKIEKEAEI--LSVLSHRNIIQFYGVILEPPNYGIVTEYASLGSLYDYINSN
       .::::::.  . ::..:  :  :.: ::: : ::  . : : :. :. . :.::. . ..
NP_006 EEVAVKKVRDL-KETDIKHLRKLKHPNIITFKGVCTQAPCYCILMEFCAQGQLYEVLRAG
        150        160       170       180       190       200     

       100       110       120       130       140       150       
pF1KB3 RSEEMDMDHIMTWATDVAKGMHYLHMEAPVKVIHRDLKSRNVVIAADGVLKICDFGASR-
       :    ..  .. :.  .: ::.:::..   :.::::::: :..:. : :.:: :::.:. 
NP_006 RPVTPSL--LVDWSMGIAGGMNYLHLH---KIIHRDLKSPNMLITYDDVVKISDFGTSKE
         210         220       230          240       250       260

        160       170       180       190       200       210      
pF1KB3 FHNHTTHMSLVGTFPWMAPEVIQSLPVSETCDTYSYGVVLWEMLTREVPFKGLEGLQVAW
       . ...:.::..::  :::::::.. ::::  : .:.::::::.:: :.:.: ...  . :
NP_006 LSDKSTKMSFAGTVAWMAPEVIRNEPVSEKVDIWSFGVVLWELLTGEIPYKDVDSSAIIW
              270       280       290       300       310       320

        220       230       240       250       260        270     
pF1KB3 LVVEKNERLTIPSSCPRSFAELLHQCWEADAKKRPSFKQIISILESMSNDT-SLPDKCNS
        :  .. .: .::::: .:  ::.:::..  ..::::.::.  :.  : :. : :..  .
NP_006 GVGSNSLHLPVPSSCPDGFKILLRQCWNSKPRNRPSFRQILLHLDIASADVLSTPQE--T
              330       340       350       360       370          

         280       290       300       310       320       330     
pF1KB3 FLHNKAEWRCEIEATLERLKKLERDLSFKEQELKERERRLKMWEQKLTEQSNTPLLPSFE
       .....:::: :..  .:..:.    :   :.::  :.:                      
NP_006 YFKSQAEWREEVKLHFEKIKSEGTCLHRLEEELVMRRREELRHALDIREHYERKLERANN
      380       390       400       410       420       430        

         340       350       360       370       380       390     
pF1KB3 IGAWTEDDVYCWVQQLVRKGDSSAEMSVYASLFKENNITGKRLLLLEEEDLKDMGIVSKG
                                                                   
NP_006 LYMELNALMLQLELKERELLRREQALERRCPGLLKPHPSRGLLHGNTMEKLIKKRNVPQK
      440       450       460       470       480       490        

>>NP_001180440 (OMIM: 600447) mitogen-activated protein   (892 aa)
 initn: 404 init1: 376 opt: 739  Z-score: 308.4  bits: 68.1 E(85289): 1.9e-10
Smith-Waterman score: 739; 39.9% identity (70.5% similar) in 308 aa overlap (10-313:152-449)

                                    10        20        30         
pF1KB3                      MSSLGASFVQIKFDDLQFFENCGGGSFGSVYRAKWISQD
                                     .. :...  ..  :.:. :.:. ...  . 
NP_001 EGLFGCLRPVWTMIGKAYSTEHKQQQEDLWEVPFEEILDLQWVGSGAQGAVFLGRF--HG
             130       140       150       160       170           

      40        50          60        70        80        90       
pF1KB3 KEVAVKKLLKIEKEAEI--LSVLSHRNIIQFYGVILEPPNYGIVTEYASLGSLYDYINSN
       .::::::.  . ::..:  :  :.: ::: : ::  . : : :. :. . :.::. . ..
NP_001 EEVAVKKVRDL-KETDIKHLRKLKHPNIITFKGVCTQAPCYCILMEFCAQGQLYEVLRAG
     180       190        200       210       220       230        

       100       110       120       130       140       150       
pF1KB3 RSEEMDMDHIMTWATDVAKGMHYLHMEAPVKVIHRDLKSRNVVIAADGVLKICDFGASR-
       :    ..  .. :.  .: ::.:::..   :.::::::: :..:. : :.:: :::.:. 
NP_001 RPVTPSL--LVDWSMGIAGGMNYLHLH---KIIHRDLKSPNMLITYDDVVKISDFGTSKE
      240         250       260          270       280       290   

        160       170       180       190       200       210      
pF1KB3 FHNHTTHMSLVGTFPWMAPEVIQSLPVSETCDTYSYGVVLWEMLTREVPFKGLEGLQVAW
       . ...:.::..::  :::::::.. ::::  : .:.::::::.:: :.:.: ...  . :
NP_001 LSDKSTKMSFAGTVAWMAPEVIRNEPVSEKVDIWSFGVVLWELLTGEIPYKDVDSSAIIW
           300       310       320       330       340       350   

        220       230       240       250       260        270     
pF1KB3 LVVEKNERLTIPSSCPRSFAELLHQCWEADAKKRPSFKQIISILESMSNDT-SLPDKCNS
        :  .. .: .::::: .:  ::.:::..  ..::::.::.  :.  : :. : :..  .
NP_001 GVGSNSLHLPVPSSCPDGFKILLRQCWNSKPRNRPSFRQILLHLDIASADVLSTPQE--T
           360       370       380       390       400       410   

         280       290       300       310       320       330     
pF1KB3 FLHNKAEWRCEIEATLERLKKLERDLSFKEQELKERERRLKMWEQKLTEQSNTPLLPSFE
       .....:::: :..  .:..:.    :   :.::  :.:                      
NP_001 YFKSQAEWREEVKLHFEKIKSEGTCLHRLEEELVMRRREELRHALDIREHYERKLERANN
             420       430       440       450       460       470 

         340       350       360       370       380       390     
pF1KB3 IGAWTEDDVYCWVQQLVRKGDSSAEMSVYASLFKENNITGKRLLLLEEEDLKDMGIVSKG
                                                                   
NP_001 LYMELNALMLQLELKERELLRREQALERRCPGLLKPHPSRGLLHGNTMEKLIKKRNVPQK
             480       490       500       510       520       530 

>>XP_005269195 (OMIM: 600447) PREDICTED: mitogen-activat  (892 aa)
 initn: 404 init1: 376 opt: 739  Z-score: 308.4  bits: 68.1 E(85289): 1.9e-10
Smith-Waterman score: 739; 39.9% identity (70.5% similar) in 308 aa overlap (10-313:152-449)

                                    10        20        30         
pF1KB3                      MSSLGASFVQIKFDDLQFFENCGGGSFGSVYRAKWISQD
                                     .. :...  ..  :.:. :.:. ...  . 
XP_005 EGLFGCLRPVWTMIGKAYSTEHKQQQEDLWEVPFEEILDLQWVGSGAQGAVFLGRF--HG
             130       140       150       160       170           

      40        50          60        70        80        90       
pF1KB3 KEVAVKKLLKIEKEAEI--LSVLSHRNIIQFYGVILEPPNYGIVTEYASLGSLYDYINSN
       .::::::.  . ::..:  :  :.: ::: : ::  . : : :. :. . :.::. . ..
XP_005 EEVAVKKVRDL-KETDIKHLRKLKHPNIITFKGVCTQAPCYCILMEFCAQGQLYEVLRAG
     180       190        200       210       220       230        

       100       110       120       130       140       150       
pF1KB3 RSEEMDMDHIMTWATDVAKGMHYLHMEAPVKVIHRDLKSRNVVIAADGVLKICDFGASR-
       :    ..  .. :.  .: ::.:::..   :.::::::: :..:. : :.:: :::.:. 
XP_005 RPVTPSL--LVDWSMGIAGGMNYLHLH---KIIHRDLKSPNMLITYDDVVKISDFGTSKE
      240         250       260          270       280       290   

        160       170       180       190       200       210      
pF1KB3 FHNHTTHMSLVGTFPWMAPEVIQSLPVSETCDTYSYGVVLWEMLTREVPFKGLEGLQVAW
       . ...:.::..::  :::::::.. ::::  : .:.::::::.:: :.:.: ...  . :
XP_005 LSDKSTKMSFAGTVAWMAPEVIRNEPVSEKVDIWSFGVVLWELLTGEIPYKDVDSSAIIW
           300       310       320       330       340       350   

        220       230       240       250       260        270     
pF1KB3 LVVEKNERLTIPSSCPRSFAELLHQCWEADAKKRPSFKQIISILESMSNDT-SLPDKCNS
        :  .. .: .::::: .:  ::.:::..  ..::::.::.  :.  : :. : :..  .
XP_005 GVGSNSLHLPVPSSCPDGFKILLRQCWNSKPRNRPSFRQILLHLDIASADVLSTPQE--T
           360       370       380       390       400       410   

         280       290       300       310       320       330     
pF1KB3 FLHNKAEWRCEIEATLERLKKLERDLSFKEQELKERERRLKMWEQKLTEQSNTPLLPSFE
       .....:::: :..  .:..:.    :   :.::  :.:                      
XP_005 YFKSQAEWREEVKLHFEKIKSEGTCLHRLEEELVMRRREELRHALDIREHYERKLERANN
             420       430       440       450       460       470 

         340       350       360       370       380       390     
pF1KB3 IGAWTEDDVYCWVQQLVRKGDSSAEMSVYASLFKENNITGKRLLLLEEEDLKDMGIVSKG
                                                                   
XP_005 LYMELNALMLQLELKERELLRREQALERRCPGLLKPHPSRGLLHGNTMEKLIKKRNVPQK
             480       490       500       510       520       530 




800 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Thu Nov  3 13:15:56 2016 done: Thu Nov  3 13:15:58 2016
 Total Scan time: 13.340 Total Display time:  0.130

Function used was FASTA [36.3.4 Apr, 2011]
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