Result of FASTA (omim) for pF1KB3048
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB3048, 1342 aa
  1>>>pF1KB3048 1342 - 1342 aa - 1342 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 8.7576+/-0.000503; mu= 7.0038+/- 0.031
 mean_var=242.8914+/-49.218, 0's: 0 Z-trim(116.3): 539  B-trim: 0 in 0/55
 Lambda= 0.082294
 statistics sampled from 26712 (27317) to 26712 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.663), E-opt: 0.2 (0.32), width:  16
 Scan time: 16.510

The best scores are:                                      opt bits E(85289)
NP_001159737 (OMIM: 150390) latent-transforming gr (1342) 9897 1190.0       0
XP_005264374 (OMIM: 150390) PREDICTED: latent-tran (1668) 9772 1175.2       0
XP_011531161 (OMIM: 150390) PREDICTED: latent-tran (1669) 9759 1173.7       0
NP_000618 (OMIM: 150390) latent-transforming growt (1395) 7097 857.5       0
NP_996826 (OMIM: 150390) latent-transforming growt (1721) 7097 857.6       0
XP_011531162 (OMIM: 150390) PREDICTED: latent-tran (1666) 7080 855.6       0
XP_011531155 (OMIM: 150390) PREDICTED: latent-tran (1722) 7080 855.6       0
XP_011531157 (OMIM: 150390) PREDICTED: latent-tran (1720) 7075 855.0       0
NP_001159738 (OMIM: 150390) latent-transforming gr (1300) 6602 798.7       0
XP_005264375 (OMIM: 150390) PREDICTED: latent-tran (1626) 6482 784.6       0
XP_011531160 (OMIM: 150390) PREDICTED: latent-tran (1680) 6102 739.5 4.7e-212
XP_016859597 (OMIM: 150390) PREDICTED: latent-tran (1681) 5523 670.7 2.3e-191
XP_011531158 (OMIM: 150390) PREDICTED: latent-tran (1682) 5517 670.0 3.8e-191
XP_011531159 (OMIM: 150390) PREDICTED: latent-tran (1680) 4520 551.7 1.6e-155
XP_016859599 (OMIM: 150390) PREDICTED: latent-tran (1639) 4368 533.6 4.4e-150
NP_001159736 (OMIM: 150390) latent-transforming gr (1353) 3802 466.3 6.5e-130
XP_016859598 (OMIM: 150390) PREDICTED: latent-tran (1679) 3802 466.4 7.5e-130
XP_011531163 (OMIM: 150390) PREDICTED: latent-tran (1632) 3585 440.6 4.2e-122
XP_011531164 (OMIM: 150390) PREDICTED: latent-tran (1248) 3574 439.2 8.6e-122
XP_011525685 (OMIM: 604710,613177) PREDICTED: late (1522) 2179 273.7 7.1e-72
XP_011525687 (OMIM: 604710,613177) PREDICTED: late (1478) 2032 256.2 1.3e-66
XP_011525688 (OMIM: 604710,613177) PREDICTED: late (1436) 2017 254.4 4.2e-66
NP_066548 (OMIM: 601216,602090,613097) latent-tran (1256) 1996 251.9 2.2e-65
XP_016882843 (OMIM: 604710,613177) PREDICTED: late (1438) 1990 251.2 3.9e-65
NP_001123616 (OMIM: 601216,602090,613097) latent-t (1303) 1978 249.8 9.7e-65
XP_011525686 (OMIM: 604710,613177) PREDICTED: late (1480) 1965 248.3 3.1e-64
XP_011525680 (OMIM: 604710,613177) PREDICTED: late (1611) 1820 231.1   5e-59
NP_000419 (OMIM: 251750,600975,602091,613086,61481 (1821) 1780 226.4 1.5e-57
XP_011535067 (OMIM: 251750,600975,602091,613086,61 (1694) 1753 223.2 1.3e-56
NP_001157738 (OMIM: 601216,602090,613097) latent-t (1139) 1719 219.0 1.6e-55
XP_011543335 (OMIM: 601216,602090,613097) PREDICTE (1265) 1592 203.9 5.9e-51
XP_011543334 (OMIM: 601216,602090,613097) PREDICTE (1312) 1574 201.8 2.7e-50
NP_000129 (OMIM: 102370,129600,134797,154700,18490 (2871) 1172 154.4 1.1e-35
XP_016882864 (OMIM: 608529) PREDICTED: fibrillin-3 (2768) 1170 154.1 1.3e-35
XP_016864717 (OMIM: 121050,612570,616118) PREDICTE (2861) 1169 154.0 1.4e-35
NP_001990 (OMIM: 121050,612570,616118) fibrillin-2 (2912) 1169 154.0 1.4e-35
XP_016882866 (OMIM: 608529) PREDICTED: fibrillin-3 (1948) 1138 150.2 1.4e-34
XP_016882865 (OMIM: 608529) PREDICTED: fibrillin-3 (2766) 1138 150.3 1.8e-34
XP_016882863 (OMIM: 608529) PREDICTED: fibrillin-3 (2777) 1138 150.3 1.8e-34
XP_016882862 (OMIM: 608529) PREDICTED: fibrillin-3 (2789) 1138 150.3 1.8e-34
NP_115823 (OMIM: 608529) fibrillin-3 precursor [Ho (2809) 1138 150.3 1.8e-34
NP_001308360 (OMIM: 608529) fibrillin-3 precursor  (2809) 1138 150.3 1.8e-34
XP_016882861 (OMIM: 608529) PREDICTED: fibrillin-3 (2809) 1138 150.3 1.8e-34
XP_016882868 (OMIM: 608529) PREDICTED: fibrillin-3 (2851) 1138 150.3 1.8e-34
XP_016882867 (OMIM: 608529) PREDICTED: fibrillin-3 (1595) 1132 149.4 1.9e-34
XP_011508340 (OMIM: 603075,608548) PREDICTED: hemi (5518)  858 117.4 2.9e-24
XP_016868907 (OMIM: 602108) PREDICTED: matrilin-2  ( 799)  799 109.6 9.4e-23
XP_005250977 (OMIM: 602108) PREDICTED: matrilin-2  ( 818)  799 109.6 9.5e-23
NP_085072 (OMIM: 602108) matrilin-2 isoform b prec ( 937)  799 109.7 1.1e-22
NP_002371 (OMIM: 602108) matrilin-2 isoform a prec ( 956)  799 109.7 1.1e-22


>>NP_001159737 (OMIM: 150390) latent-transforming growth  (1342 aa)
 initn: 9897 init1: 9897 opt: 9897  Z-score: 6364.3  bits: 1190.0 E(85289):    0
Smith-Waterman score: 9897; 100.0% identity (100.0% similar) in 1342 aa overlap (1-1342:1-1342)

               10        20        30        40        50        60
pF1KB3 MDTKLMCLLFFFSLPPLLVSNHTGRIKVVFTPSICKVTCTKGSCQNSCEKGNTTTLISEN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MDTKLMCLLFFFSLPPLLVSNHTGRIKVVFTPSICKVTCTKGSCQNSCEKGNTTTLISEN
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB3 GHAADTLTATNFRVVICHLPCMNGGQCSSRDKCQCPPNFTGKLCQIPVHGASVPKLYQHS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GHAADTLTATNFRVVICHLPCMNGGQCSSRDKCQCPPNFTGKLCQIPVHGASVPKLYQHS
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB3 QQPGKALGTHVIHSTHTLPLTVTSQQGVKVKFPPNIVNIHVKHPPEASVQIHQVSRIDGP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QQPGKALGTHVIHSTHTLPLTVTSQQGVKVKFPPNIVNIHVKHPPEASVQIHQVSRIDGP
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB3 TGQKTKEAQPGQSQVSYQGLPVQKTQTIHSTYSHQQVIPHVYPVAAKTQLGRCFQETIGS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TGQKTKEAQPGQSQVSYQGLPVQKTQTIHSTYSHQQVIPHVYPVAAKTQLGRCFQETIGS
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB3 QCGKALPGLSKQEDCCGTVGTSWGFNKCQKCPKKPSYHGYNQMMECLPGYKRVNNTFCQD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QCGKALPGLSKQEDCCGTVGTSWGFNKCQKCPKKPSYHGYNQMMECLPGYKRVNNTFCQD
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB3 INECQLQGVCPNGECLNTMGSYRCTCKIGFGPDPTFSSCVPDPPVISEEKGPCYRLVSSG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 INECQLQGVCPNGECLNTMGSYRCTCKIGFGPDPTFSSCVPDPPVISEEKGPCYRLVSSG
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB3 RQCMHPLSVHLTKQLCCCSVGKAWGPHCEKCPLPGTAKEEPVEALTFSREHGPGVAEPEV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RQCMHPLSVHLTKQLCCCSVGKAWGPHCEKCPLPGTAKEEPVEALTFSREHGPGVAEPEV
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KB3 ATAPPEKEIPSLDQEKTKLEPGQPQLSPGISTIHLHPQFPVVIEKTSPPVPVEVAPEAST
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ATAPPEKEIPSLDQEKTKLEPGQPQLSPGISTIHLHPQFPVVIEKTSPPVPVEVAPEAST
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KB3 SSASQVIAPTQVTEINECTVNPDICGAGHCINLPVRYTCICYEGYRFSEQQRKCVDIDEC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SSASQVIAPTQVTEINECTVNPDICGAGHCINLPVRYTCICYEGYRFSEQQRKCVDIDEC
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KB3 TQVQHLCSQGRCENTEGSFLCICPAGFMASEEGTNCIDVDECLRPDVCGEGHCVNTVGAF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TQVQHLCSQGRCENTEGSFLCICPAGFMASEEGTNCIDVDECLRPDVCGEGHCVNTVGAF
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KB3 RCEYCDSGYRMTQRGRCEDIDECLNPSTCPDEQCVNSPGSYQCVPCTEGFRGWNGQCLDV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RCEYCDSGYRMTQRGRCEDIDECLNPSTCPDEQCVNSPGSYQCVPCTEGFRGWNGQCLDV
              610       620       630       640       650       660

              670       680       690       700       710       720
pF1KB3 DECLEPNVCANGDCSNLEGSYMCSCHKGYTRTPDHKHCRDIDECQQGNLCVNGQCKNTEG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DECLEPNVCANGDCSNLEGSYMCSCHKGYTRTPDHKHCRDIDECQQGNLCVNGQCKNTEG
              670       680       690       700       710       720

              730       740       750       760       770       780
pF1KB3 SFRCTCGQGYQLSAAKDQCEDIDECQHRHLCAHGQCRNTEGSFQCVCDQGYRASGLGDHC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SFRCTCGQGYQLSAAKDQCEDIDECQHRHLCAHGQCRNTEGSFQCVCDQGYRASGLGDHC
              730       740       750       760       770       780

              790       800       810       820       830       840
pF1KB3 EDINECLEDKSVCQRGDCINTAGSYDCTCPDGFQLDDNKTCQDINECEHPGLCGPQGECL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EDINECLEDKSVCQRGDCINTAGSYDCTCPDGFQLDDNKTCQDINECEHPGLCGPQGECL
              790       800       810       820       830       840

              850       860       870       880       890       900
pF1KB3 NTEGSFHCVCQQGFSISADGRTCEDIDECVNNTVCDSHGFCDNTAGSFRCLCYQGFQAPQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NTEGSFHCVCQQGFSISADGRTCEDIDECVNNTVCDSHGFCDNTAGSFRCLCYQGFQAPQ
              850       860       870       880       890       900

              910       920       930       940       950       960
pF1KB3 DGQGCVDVNECELLSGVCGEAFCENVEGSFLCVCADENQEYSPMTGQCRSRTSTDLDVDV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DGQGCVDVNECELLSGVCGEAFCENVEGSFLCVCADENQEYSPMTGQCRSRTSTDLDVDV
              910       920       930       940       950       960

              970       980       990      1000      1010      1020
pF1KB3 DQPKEEKKECYYNLNDASLCDNVLAPNVTKQECCCTSGAGWGDNCEIFPCPVLGTAEFTE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DQPKEEKKECYYNLNDASLCDNVLAPNVTKQECCCTSGAGWGDNCEIFPCPVLGTAEFTE
              970       980       990      1000      1010      1020

             1030      1040      1050      1060      1070      1080
pF1KB3 MCPKGKGFVPAGESSSEAGGENYKDADECLLFGQEICKNGFCLNTRPGYECYCKQGTYYD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MCPKGKGFVPAGESSSEAGGENYKDADECLLFGQEICKNGFCLNTRPGYECYCKQGTYYD
             1030      1040      1050      1060      1070      1080

             1090      1100      1110      1120      1130      1140
pF1KB3 PVKLQCFDMDECQDPSSCIDGQCVNTEGSYNCFCTHPMVLDASEKRCIRPAESNEQIEET
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PVKLQCFDMDECQDPSSCIDGQCVNTEGSYNCFCTHPMVLDASEKRCIRPAESNEQIEET
             1090      1100      1110      1120      1130      1140

             1150      1160      1170      1180      1190      1200
pF1KB3 DVYQDLCWEHLSDEYVCSRPLVGKQTTYTECCCLYGEAWGMQCALCPLKDSDDYAQLCNI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DVYQDLCWEHLSDEYVCSRPLVGKQTTYTECCCLYGEAWGMQCALCPLKDSDDYAQLCNI
             1150      1160      1170      1180      1190      1200

             1210      1220      1230      1240      1250      1260
pF1KB3 PVTGRRQPYGRDALVDFSEQYTPEADPYFIQDRFLNSFEELQAEECGILNGCENGRCVRV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PVTGRRQPYGRDALVDFSEQYTPEADPYFIQDRFLNSFEELQAEECGILNGCENGRCVRV
             1210      1220      1230      1240      1250      1260

             1270      1280      1290      1300      1310      1320
pF1KB3 QEGYTCDCFDGYHLDTAKMTCVDVNECDELNNRMSLCKNAKCINTDGSYKCLCLPGYVPS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QEGYTCDCFDGYHLDTAKMTCVDVNECDELNNRMSLCKNAKCINTDGSYKCLCLPGYVPS
             1270      1280      1290      1300      1310      1320

             1330      1340  
pF1KB3 DKPNYCTPLNTALNLEKDSDLE
       ::::::::::::::::::::::
NP_001 DKPNYCTPLNTALNLEKDSDLE
             1330      1340  

>>XP_005264374 (OMIM: 150390) PREDICTED: latent-transfor  (1668 aa)
 initn: 9772 init1: 9772 opt: 9772  Z-score: 6282.8  bits: 1175.2 E(85289):    0
Smith-Waterman score: 9772; 99.7% identity (99.9% similar) in 1327 aa overlap (16-1342:342-1668)

                              10        20        30        40     
pF1KB3                MDTKLMCLLFFFSLPPLLVSNHTGRIKVVFTPSICKVTCTKGSCQ
                                     :. .::::::::::::::::::::::::::
XP_005 KYFPAQKGISGEQSTEGSFPLRYVQDQVAAPFQLSNHTGRIKVVFTPSICKVTCTKGSCQ
             320       330       340       350       360       370 

          50        60        70        80        90       100     
pF1KB3 NSCEKGNTTTLISENGHAADTLTATNFRVVICHLPCMNGGQCSSRDKCQCPPNFTGKLCQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 NSCEKGNTTTLISENGHAADTLTATNFRVVICHLPCMNGGQCSSRDKCQCPPNFTGKLCQ
             380       390       400       410       420       430 

         110       120       130       140       150       160     
pF1KB3 IPVHGASVPKLYQHSQQPGKALGTHVIHSTHTLPLTVTSQQGVKVKFPPNIVNIHVKHPP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 IPVHGASVPKLYQHSQQPGKALGTHVIHSTHTLPLTVTSQQGVKVKFPPNIVNIHVKHPP
             440       450       460       470       480       490 

         170       180       190       200       210       220     
pF1KB3 EASVQIHQVSRIDGPTGQKTKEAQPGQSQVSYQGLPVQKTQTIHSTYSHQQVIPHVYPVA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EASVQIHQVSRIDGPTGQKTKEAQPGQSQVSYQGLPVQKTQTIHSTYSHQQVIPHVYPVA
             500       510       520       530       540       550 

         230       240       250       260       270       280     
pF1KB3 AKTQLGRCFQETIGSQCGKALPGLSKQEDCCGTVGTSWGFNKCQKCPKKPSYHGYNQMME
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 AKTQLGRCFQETIGSQCGKALPGLSKQEDCCGTVGTSWGFNKCQKCPKKPSYHGYNQMME
             560       570       580       590       600       610 

         290       300       310       320       330       340     
pF1KB3 CLPGYKRVNNTFCQDINECQLQGVCPNGECLNTMGSYRCTCKIGFGPDPTFSSCVPDPPV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 CLPGYKRVNNTFCQDINECQLQGVCPNGECLNTMGSYRCTCKIGFGPDPTFSSCVPDPPV
             620       630       640       650       660       670 

         350       360       370       380       390       400     
pF1KB3 ISEEKGPCYRLVSSGRQCMHPLSVHLTKQLCCCSVGKAWGPHCEKCPLPGTAKEEPVEAL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ISEEKGPCYRLVSSGRQCMHPLSVHLTKQLCCCSVGKAWGPHCEKCPLPGTAKEEPVEAL
             680       690       700       710       720       730 

         410       420       430       440       450       460     
pF1KB3 TFSREHGPGVAEPEVATAPPEKEIPSLDQEKTKLEPGQPQLSPGISTIHLHPQFPVVIEK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TFSREHGPGVAEPEVATAPPEKEIPSLDQEKTKLEPGQPQLSPGISTIHLHPQFPVVIEK
             740       750       760       770       780       790 

         470       480       490       500       510       520     
pF1KB3 TSPPVPVEVAPEASTSSASQVIAPTQVTEINECTVNPDICGAGHCINLPVRYTCICYEGY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TSPPVPVEVAPEASTSSASQVIAPTQVTEINECTVNPDICGAGHCINLPVRYTCICYEGY
             800       810       820       830       840       850 

         530       540       550       560       570       580     
pF1KB3 RFSEQQRKCVDIDECTQVQHLCSQGRCENTEGSFLCICPAGFMASEEGTNCIDVDECLRP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RFSEQQRKCVDIDECTQVQHLCSQGRCENTEGSFLCICPAGFMASEEGTNCIDVDECLRP
             860       870       880       890       900       910 

         590       600       610       620       630       640     
pF1KB3 DVCGEGHCVNTVGAFRCEYCDSGYRMTQRGRCEDIDECLNPSTCPDEQCVNSPGSYQCVP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DVCGEGHCVNTVGAFRCEYCDSGYRMTQRGRCEDIDECLNPSTCPDEQCVNSPGSYQCVP
             920       930       940       950       960       970 

         650       660       670       680       690       700     
pF1KB3 CTEGFRGWNGQCLDVDECLEPNVCANGDCSNLEGSYMCSCHKGYTRTPDHKHCRDIDECQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 CTEGFRGWNGQCLDVDECLEPNVCANGDCSNLEGSYMCSCHKGYTRTPDHKHCRDIDECQ
             980       990      1000      1010      1020      1030 

         710       720       730       740       750       760     
pF1KB3 QGNLCVNGQCKNTEGSFRCTCGQGYQLSAAKDQCEDIDECQHRHLCAHGQCRNTEGSFQC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QGNLCVNGQCKNTEGSFRCTCGQGYQLSAAKDQCEDIDECQHRHLCAHGQCRNTEGSFQC
            1040      1050      1060      1070      1080      1090 

         770       780       790       800       810       820     
pF1KB3 VCDQGYRASGLGDHCEDINECLEDKSVCQRGDCINTAGSYDCTCPDGFQLDDNKTCQDIN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VCDQGYRASGLGDHCEDINECLEDKSVCQRGDCINTAGSYDCTCPDGFQLDDNKTCQDIN
            1100      1110      1120      1130      1140      1150 

         830       840       850       860       870       880     
pF1KB3 ECEHPGLCGPQGECLNTEGSFHCVCQQGFSISADGRTCEDIDECVNNTVCDSHGFCDNTA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ECEHPGLCGPQGECLNTEGSFHCVCQQGFSISADGRTCEDIDECVNNTVCDSHGFCDNTA
            1160      1170      1180      1190      1200      1210 

         890       900       910       920       930       940     
pF1KB3 GSFRCLCYQGFQAPQDGQGCVDVNECELLSGVCGEAFCENVEGSFLCVCADENQEYSPMT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GSFRCLCYQGFQAPQDGQGCVDVNECELLSGVCGEAFCENVEGSFLCVCADENQEYSPMT
            1220      1230      1240      1250      1260      1270 

         950       960       970       980       990      1000     
pF1KB3 GQCRSRTSTDLDVDVDQPKEEKKECYYNLNDASLCDNVLAPNVTKQECCCTSGAGWGDNC
       :::::::::::::::::::::::::::::::::::::::::::::::::::::.::::::
XP_005 GQCRSRTSTDLDVDVDQPKEEKKECYYNLNDASLCDNVLAPNVTKQECCCTSGVGWGDNC
            1280      1290      1300      1310      1320      1330 

        1010      1020      1030      1040      1050      1060     
pF1KB3 EIFPCPVLGTAEFTEMCPKGKGFVPAGESSSEAGGENYKDADECLLFGQEICKNGFCLNT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EIFPCPVLGTAEFTEMCPKGKGFVPAGESSSEAGGENYKDADECLLFGQEICKNGFCLNT
            1340      1350      1360      1370      1380      1390 

        1070      1080      1090      1100      1110      1120     
pF1KB3 RPGYECYCKQGTYYDPVKLQCFDMDECQDPSSCIDGQCVNTEGSYNCFCTHPMVLDASEK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RPGYECYCKQGTYYDPVKLQCFDMDECQDPSSCIDGQCVNTEGSYNCFCTHPMVLDASEK
            1400      1410      1420      1430      1440      1450 

        1130      1140      1150      1160      1170      1180     
pF1KB3 RCIRPAESNEQIEETDVYQDLCWEHLSDEYVCSRPLVGKQTTYTECCCLYGEAWGMQCAL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RCIRPAESNEQIEETDVYQDLCWEHLSDEYVCSRPLVGKQTTYTECCCLYGEAWGMQCAL
            1460      1470      1480      1490      1500      1510 

        1190      1200      1210      1220      1230      1240     
pF1KB3 CPLKDSDDYAQLCNIPVTGRRQPYGRDALVDFSEQYTPEADPYFIQDRFLNSFEELQAEE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 CPLKDSDDYAQLCNIPVTGRRQPYGRDALVDFSEQYTPEADPYFIQDRFLNSFEELQAEE
            1520      1530      1540      1550      1560      1570 

        1250      1260      1270      1280      1290      1300     
pF1KB3 CGILNGCENGRCVRVQEGYTCDCFDGYHLDTAKMTCVDVNECDELNNRMSLCKNAKCINT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 CGILNGCENGRCVRVQEGYTCDCFDGYHLDTAKMTCVDVNECDELNNRMSLCKNAKCINT
            1580      1590      1600      1610      1620      1630 

        1310      1320      1330      1340  
pF1KB3 DGSYKCLCLPGYVPSDKPNYCTPLNTALNLEKDSDLE
       :::::::::::::::::::::::::::::::::::::
XP_005 DGSYKCLCLPGYVPSDKPNYCTPLNTALNLEKDSDLE
            1640      1650      1660        

>>XP_011531161 (OMIM: 150390) PREDICTED: latent-transfor  (1669 aa)
 initn: 6585 init1: 6585 opt: 9759  Z-score: 6274.5  bits: 1173.7 E(85289):    0
Smith-Waterman score: 9759; 99.5% identity (99.8% similar) in 1328 aa overlap (16-1342:342-1669)

                              10        20        30        40     
pF1KB3                MDTKLMCLLFFFSLPPLLVSNHTGRIKVVFTPSICKVTCTKGSCQ
                                     :. .::::::::::::::::::::::::::
XP_011 KYFPAQKGISGEQSTEGSFPLRYVQDQVAAPFQLSNHTGRIKVVFTPSICKVTCTKGSCQ
             320       330       340       350       360       370 

          50        60        70        80        90       100     
pF1KB3 NSCEKGNTTTLISENGHAADTLTATNFRVVICHLPCMNGGQCSSRDKCQCPPNFTGKLCQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NSCEKGNTTTLISENGHAADTLTATNFRVVICHLPCMNGGQCSSRDKCQCPPNFTGKLCQ
             380       390       400       410       420       430 

         110       120       130       140       150       160     
pF1KB3 IPVHGASVPKLYQHSQQPGKALGTHVIHSTHTLPLTVTSQQGVKVKFPPNIVNIHVKHPP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IPVHGASVPKLYQHSQQPGKALGTHVIHSTHTLPLTVTSQQGVKVKFPPNIVNIHVKHPP
             440       450       460       470       480       490 

         170       180       190       200       210       220     
pF1KB3 EASVQIHQVSRIDGPTGQKTKEAQPGQSQVSYQGLPVQKTQTIHSTYSHQQVIPHVYPVA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EASVQIHQVSRIDGPTGQKTKEAQPGQSQVSYQGLPVQKTQTIHSTYSHQQVIPHVYPVA
             500       510       520       530       540       550 

         230       240       250       260       270       280     
pF1KB3 AKTQLGRCFQETIGSQCGKALPGLSKQEDCCGTVGTSWGFNKCQKCPKKPSYHGYNQMME
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AKTQLGRCFQETIGSQCGKALPGLSKQEDCCGTVGTSWGFNKCQKCPKKPSYHGYNQMME
             560       570       580       590       600       610 

         290       300       310       320       330       340     
pF1KB3 CLPGYKRVNNTFCQDINECQLQGVCPNGECLNTMGSYRCTCKIGFGPDPTFSSCVPDPPV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CLPGYKRVNNTFCQDINECQLQGVCPNGECLNTMGSYRCTCKIGFGPDPTFSSCVPDPPV
             620       630       640       650       660       670 

         350       360       370       380       390       400     
pF1KB3 ISEEKGPCYRLVSSGRQCMHPLSVHLTKQLCCCSVGKAWGPHCEKCPLPGTAKEEPVEAL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ISEEKGPCYRLVSSGRQCMHPLSVHLTKQLCCCSVGKAWGPHCEKCPLPGTAKEEPVEAL
             680       690       700       710       720       730 

         410       420       430       440       450       460     
pF1KB3 TFSREHGPGVAEPEVATAPPEKEIPSLDQEKTKLEPGQPQLSPGISTIHLHPQFP-VVIE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::: .:::
XP_011 TFSREHGPGVAEPEVATAPPEKEIPSLDQEKTKLEPGQPQLSPGISTIHLHPQFPGIVIE
             740       750       760       770       780       790 

          470       480       490       500       510       520    
pF1KB3 KTSPPVPVEVAPEASTSSASQVIAPTQVTEINECTVNPDICGAGHCINLPVRYTCICYEG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KTSPPVPVEVAPEASTSSASQVIAPTQVTEINECTVNPDICGAGHCINLPVRYTCICYEG
             800       810       820       830       840       850 

          530       540       550       560       570       580    
pF1KB3 YRFSEQQRKCVDIDECTQVQHLCSQGRCENTEGSFLCICPAGFMASEEGTNCIDVDECLR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YRFSEQQRKCVDIDECTQVQHLCSQGRCENTEGSFLCICPAGFMASEEGTNCIDVDECLR
             860       870       880       890       900       910 

          590       600       610       620       630       640    
pF1KB3 PDVCGEGHCVNTVGAFRCEYCDSGYRMTQRGRCEDIDECLNPSTCPDEQCVNSPGSYQCV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PDVCGEGHCVNTVGAFRCEYCDSGYRMTQRGRCEDIDECLNPSTCPDEQCVNSPGSYQCV
             920       930       940       950       960       970 

          650       660       670       680       690       700    
pF1KB3 PCTEGFRGWNGQCLDVDECLEPNVCANGDCSNLEGSYMCSCHKGYTRTPDHKHCRDIDEC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PCTEGFRGWNGQCLDVDECLEPNVCANGDCSNLEGSYMCSCHKGYTRTPDHKHCRDIDEC
             980       990      1000      1010      1020      1030 

          710       720       730       740       750       760    
pF1KB3 QQGNLCVNGQCKNTEGSFRCTCGQGYQLSAAKDQCEDIDECQHRHLCAHGQCRNTEGSFQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QQGNLCVNGQCKNTEGSFRCTCGQGYQLSAAKDQCEDIDECQHRHLCAHGQCRNTEGSFQ
            1040      1050      1060      1070      1080      1090 

          770       780       790       800       810       820    
pF1KB3 CVCDQGYRASGLGDHCEDINECLEDKSVCQRGDCINTAGSYDCTCPDGFQLDDNKTCQDI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CVCDQGYRASGLGDHCEDINECLEDKSVCQRGDCINTAGSYDCTCPDGFQLDDNKTCQDI
            1100      1110      1120      1130      1140      1150 

          830       840       850       860       870       880    
pF1KB3 NECEHPGLCGPQGECLNTEGSFHCVCQQGFSISADGRTCEDIDECVNNTVCDSHGFCDNT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NECEHPGLCGPQGECLNTEGSFHCVCQQGFSISADGRTCEDIDECVNNTVCDSHGFCDNT
            1160      1170      1180      1190      1200      1210 

          890       900       910       920       930       940    
pF1KB3 AGSFRCLCYQGFQAPQDGQGCVDVNECELLSGVCGEAFCENVEGSFLCVCADENQEYSPM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AGSFRCLCYQGFQAPQDGQGCVDVNECELLSGVCGEAFCENVEGSFLCVCADENQEYSPM
            1220      1230      1240      1250      1260      1270 

          950       960       970       980       990      1000    
pF1KB3 TGQCRSRTSTDLDVDVDQPKEEKKECYYNLNDASLCDNVLAPNVTKQECCCTSGAGWGDN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::.:::::
XP_011 TGQCRSRTSTDLDVDVDQPKEEKKECYYNLNDASLCDNVLAPNVTKQECCCTSGVGWGDN
            1280      1290      1300      1310      1320      1330 

         1010      1020      1030      1040      1050      1060    
pF1KB3 CEIFPCPVLGTAEFTEMCPKGKGFVPAGESSSEAGGENYKDADECLLFGQEICKNGFCLN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CEIFPCPVLGTAEFTEMCPKGKGFVPAGESSSEAGGENYKDADECLLFGQEICKNGFCLN
            1340      1350      1360      1370      1380      1390 

         1070      1080      1090      1100      1110      1120    
pF1KB3 TRPGYECYCKQGTYYDPVKLQCFDMDECQDPSSCIDGQCVNTEGSYNCFCTHPMVLDASE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TRPGYECYCKQGTYYDPVKLQCFDMDECQDPSSCIDGQCVNTEGSYNCFCTHPMVLDASE
            1400      1410      1420      1430      1440      1450 

         1130      1140      1150      1160      1170      1180    
pF1KB3 KRCIRPAESNEQIEETDVYQDLCWEHLSDEYVCSRPLVGKQTTYTECCCLYGEAWGMQCA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KRCIRPAESNEQIEETDVYQDLCWEHLSDEYVCSRPLVGKQTTYTECCCLYGEAWGMQCA
            1460      1470      1480      1490      1500      1510 

         1190      1200      1210      1220      1230      1240    
pF1KB3 LCPLKDSDDYAQLCNIPVTGRRQPYGRDALVDFSEQYTPEADPYFIQDRFLNSFEELQAE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LCPLKDSDDYAQLCNIPVTGRRQPYGRDALVDFSEQYTPEADPYFIQDRFLNSFEELQAE
            1520      1530      1540      1550      1560      1570 

         1250      1260      1270      1280      1290      1300    
pF1KB3 ECGILNGCENGRCVRVQEGYTCDCFDGYHLDTAKMTCVDVNECDELNNRMSLCKNAKCIN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ECGILNGCENGRCVRVQEGYTCDCFDGYHLDTAKMTCVDVNECDELNNRMSLCKNAKCIN
            1580      1590      1600      1610      1620      1630 

         1310      1320      1330      1340  
pF1KB3 TDGSYKCLCLPGYVPSDKPNYCTPLNTALNLEKDSDLE
       ::::::::::::::::::::::::::::::::::::::
XP_011 TDGSYKCLCLPGYVPSDKPNYCTPLNTALNLEKDSDLE
            1640      1650      1660         

>>NP_000618 (OMIM: 150390) latent-transforming growth fa  (1395 aa)
 initn: 7026 init1: 7026 opt: 7097  Z-score: 4567.4  bits: 857.5 E(85289):    0
Smith-Waterman score: 9639; 96.1% identity (96.1% similar) in 1374 aa overlap (22-1342:22-1395)

               10        20        30        40        50        60
pF1KB3 MDTKLMCLLFFFSLPPLLVSNHTGRIKVVFTPSICKVTCTKGSCQNSCEKGNTTTLISEN
                            :::::::::::::::::::::::::::::::::::::::
NP_000 MDTKLMCLLFFFSLPPLLVSNHTGRIKVVFTPSICKVTCTKGSCQNSCEKGNTTTLISEN
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB3 GHAADTLTATNFRVVICHLPCMNGGQCSSRDKCQCPPNFTGKLCQIPVHGASVPKLYQHS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 GHAADTLTATNFRVVICHLPCMNGGQCSSRDKCQCPPNFTGKLCQIPVHGASVPKLYQHS
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB3 QQPGKALGTHVIHSTHTLPLTVTSQQGVKVKFPPNIVNIHVKHPPEASVQIHQVSRIDGP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 QQPGKALGTHVIHSTHTLPLTVTSQQGVKVKFPPNIVNIHVKHPPEASVQIHQVSRIDGP
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB3 TGQKTKEAQPGQSQVSYQGLPVQKTQTIHSTYSHQQVIPHVYPVAAKTQLGRCFQETIGS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 TGQKTKEAQPGQSQVSYQGLPVQKTQTIHSTYSHQQVIPHVYPVAAKTQLGRCFQETIGS
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB3 QCGKALPGLSKQEDCCGTVGTSWGFNKCQKCPKKPSYHGYNQMMECLPGYKRVNNTFCQD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 QCGKALPGLSKQEDCCGTVGTSWGFNKCQKCPKKPSYHGYNQMMECLPGYKRVNNTFCQD
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB3 INECQLQGVCPNGECLNTMGSYRCTCKIGFGPDPTFSSCVPDPPVISEEKGPCYRLVSSG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 INECQLQGVCPNGECLNTMGSYRCTCKIGFGPDPTFSSCVPDPPVISEEKGPCYRLVSSG
              310       320       330       340       350       360

              370       380       390                              
pF1KB3 RQCMHPLSVHLTKQLCCCSVGKAWGPHCEKCPLPGTA-----------------------
       :::::::::::::::::::::::::::::::::::::                       
NP_000 RQCMHPLSVHLTKQLCCCSVGKAWGPHCEKCPLPGTAAFKEICPGGMGYTVSGVHRRRPI
              370       380       390       400       410       420

                                     400       410       420       
pF1KB3 ------------------------------KEEPVEALTFSREHGPGVAEPEVATAPPEK
                                     ::::::::::::::::::::::::::::::
NP_000 HHHVGKGPVFVKPKNTQPVAKSTHPPPLPAKEEPVEALTFSREHGPGVAEPEVATAPPEK
              430       440       450       460       470       480

       430       440       450       460       470       480       
pF1KB3 EIPSLDQEKTKLEPGQPQLSPGISTIHLHPQFPVVIEKTSPPVPVEVAPEASTSSASQVI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 EIPSLDQEKTKLEPGQPQLSPGISTIHLHPQFPVVIEKTSPPVPVEVAPEASTSSASQVI
              490       500       510       520       530       540

       490       500       510       520       530       540       
pF1KB3 APTQVTEINECTVNPDICGAGHCINLPVRYTCICYEGYRFSEQQRKCVDIDECTQVQHLC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 APTQVTEINECTVNPDICGAGHCINLPVRYTCICYEGYRFSEQQRKCVDIDECTQVQHLC
              550       560       570       580       590       600

       550       560       570       580       590       600       
pF1KB3 SQGRCENTEGSFLCICPAGFMASEEGTNCIDVDECLRPDVCGEGHCVNTVGAFRCEYCDS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 SQGRCENTEGSFLCICPAGFMASEEGTNCIDVDECLRPDVCGEGHCVNTVGAFRCEYCDS
              610       620       630       640       650       660

       610       620       630       640       650       660       
pF1KB3 GYRMTQRGRCEDIDECLNPSTCPDEQCVNSPGSYQCVPCTEGFRGWNGQCLDVDECLEPN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 GYRMTQRGRCEDIDECLNPSTCPDEQCVNSPGSYQCVPCTEGFRGWNGQCLDVDECLEPN
              670       680       690       700       710       720

       670       680       690       700       710       720       
pF1KB3 VCANGDCSNLEGSYMCSCHKGYTRTPDHKHCRDIDECQQGNLCVNGQCKNTEGSFRCTCG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 VCANGDCSNLEGSYMCSCHKGYTRTPDHKHCRDIDECQQGNLCVNGQCKNTEGSFRCTCG
              730       740       750       760       770       780

       730       740       750       760       770       780       
pF1KB3 QGYQLSAAKDQCEDIDECQHRHLCAHGQCRNTEGSFQCVCDQGYRASGLGDHCEDINECL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 QGYQLSAAKDQCEDIDECQHRHLCAHGQCRNTEGSFQCVCDQGYRASGLGDHCEDINECL
              790       800       810       820       830       840

       790       800       810       820       830       840       
pF1KB3 EDKSVCQRGDCINTAGSYDCTCPDGFQLDDNKTCQDINECEHPGLCGPQGECLNTEGSFH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 EDKSVCQRGDCINTAGSYDCTCPDGFQLDDNKTCQDINECEHPGLCGPQGECLNTEGSFH
              850       860       870       880       890       900

       850       860       870       880       890       900       
pF1KB3 CVCQQGFSISADGRTCEDIDECVNNTVCDSHGFCDNTAGSFRCLCYQGFQAPQDGQGCVD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 CVCQQGFSISADGRTCEDIDECVNNTVCDSHGFCDNTAGSFRCLCYQGFQAPQDGQGCVD
              910       920       930       940       950       960

       910       920       930       940       950       960       
pF1KB3 VNECELLSGVCGEAFCENVEGSFLCVCADENQEYSPMTGQCRSRTSTDLDVDVDQPKEEK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 VNECELLSGVCGEAFCENVEGSFLCVCADENQEYSPMTGQCRSRTSTDLDVDVDQPKEEK
              970       980       990      1000      1010      1020

       970       980       990      1000      1010      1020       
pF1KB3 KECYYNLNDASLCDNVLAPNVTKQECCCTSGAGWGDNCEIFPCPVLGTAEFTEMCPKGKG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 KECYYNLNDASLCDNVLAPNVTKQECCCTSGAGWGDNCEIFPCPVLGTAEFTEMCPKGKG
             1030      1040      1050      1060      1070      1080

      1030      1040      1050      1060      1070      1080       
pF1KB3 FVPAGESSSEAGGENYKDADECLLFGQEICKNGFCLNTRPGYECYCKQGTYYDPVKLQCF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 FVPAGESSSEAGGENYKDADECLLFGQEICKNGFCLNTRPGYECYCKQGTYYDPVKLQCF
             1090      1100      1110      1120      1130      1140

      1090      1100      1110      1120      1130      1140       
pF1KB3 DMDECQDPSSCIDGQCVNTEGSYNCFCTHPMVLDASEKRCIRPAESNEQIEETDVYQDLC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 DMDECQDPSSCIDGQCVNTEGSYNCFCTHPMVLDASEKRCIRPAESNEQIEETDVYQDLC
             1150      1160      1170      1180      1190      1200

      1150      1160      1170      1180      1190      1200       
pF1KB3 WEHLSDEYVCSRPLVGKQTTYTECCCLYGEAWGMQCALCPLKDSDDYAQLCNIPVTGRRQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 WEHLSDEYVCSRPLVGKQTTYTECCCLYGEAWGMQCALCPLKDSDDYAQLCNIPVTGRRQ
             1210      1220      1230      1240      1250      1260

      1210      1220      1230      1240      1250      1260       
pF1KB3 PYGRDALVDFSEQYTPEADPYFIQDRFLNSFEELQAEECGILNGCENGRCVRVQEGYTCD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 PYGRDALVDFSEQYTPEADPYFIQDRFLNSFEELQAEECGILNGCENGRCVRVQEGYTCD
             1270      1280      1290      1300      1310      1320

      1270      1280      1290      1300      1310      1320       
pF1KB3 CFDGYHLDTAKMTCVDVNECDELNNRMSLCKNAKCINTDGSYKCLCLPGYVPSDKPNYCT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 CFDGYHLDTAKMTCVDVNECDELNNRMSLCKNAKCINTDGSYKCLCLPGYVPSDKPNYCT
             1330      1340      1350      1360      1370      1380

      1330      1340  
pF1KB3 PLNTALNLEKDSDLE
       :::::::::::::::
NP_000 PLNTALNLEKDSDLE
             1390     

>>NP_996826 (OMIM: 150390) latent-transforming growth fa  (1721 aa)
 initn: 7026 init1: 7026 opt: 7097  Z-score: 4566.3  bits: 857.6 E(85289):    0
Smith-Waterman score: 9639; 96.1% identity (96.1% similar) in 1374 aa overlap (22-1342:348-1721)

                        10        20        30        40        50 
pF1KB3          MDTKLMCLLFFFSLPPLLVSNHTGRIKVVFTPSICKVTCTKGSCQNSCEKG
                                     ::::::::::::::::::::::::::::::
NP_996 KGISGEQSTEGSFPLRYVQDQVAAPFQLSNHTGRIKVVFTPSICKVTCTKGSCQNSCEKG
       320       330       340       350       360       370       

              60        70        80        90       100       110 
pF1KB3 NTTTLISENGHAADTLTATNFRVVICHLPCMNGGQCSSRDKCQCPPNFTGKLCQIPVHGA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_996 NTTTLISENGHAADTLTATNFRVVICHLPCMNGGQCSSRDKCQCPPNFTGKLCQIPVHGA
       380       390       400       410       420       430       

             120       130       140       150       160       170 
pF1KB3 SVPKLYQHSQQPGKALGTHVIHSTHTLPLTVTSQQGVKVKFPPNIVNIHVKHPPEASVQI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_996 SVPKLYQHSQQPGKALGTHVIHSTHTLPLTVTSQQGVKVKFPPNIVNIHVKHPPEASVQI
       440       450       460       470       480       490       

             180       190       200       210       220       230 
pF1KB3 HQVSRIDGPTGQKTKEAQPGQSQVSYQGLPVQKTQTIHSTYSHQQVIPHVYPVAAKTQLG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_996 HQVSRIDGPTGQKTKEAQPGQSQVSYQGLPVQKTQTIHSTYSHQQVIPHVYPVAAKTQLG
       500       510       520       530       540       550       

             240       250       260       270       280       290 
pF1KB3 RCFQETIGSQCGKALPGLSKQEDCCGTVGTSWGFNKCQKCPKKPSYHGYNQMMECLPGYK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_996 RCFQETIGSQCGKALPGLSKQEDCCGTVGTSWGFNKCQKCPKKPSYHGYNQMMECLPGYK
       560       570       580       590       600       610       

             300       310       320       330       340       350 
pF1KB3 RVNNTFCQDINECQLQGVCPNGECLNTMGSYRCTCKIGFGPDPTFSSCVPDPPVISEEKG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_996 RVNNTFCQDINECQLQGVCPNGECLNTMGSYRCTCKIGFGPDPTFSSCVPDPPVISEEKG
       620       630       640       650       660       670       

             360       370       380       390                     
pF1KB3 PCYRLVSSGRQCMHPLSVHLTKQLCCCSVGKAWGPHCEKCPLPGTA--------------
       ::::::::::::::::::::::::::::::::::::::::::::::              
NP_996 PCYRLVSSGRQCMHPLSVHLTKQLCCCSVGKAWGPHCEKCPLPGTAAFKEICPGGMGYTV
       680       690       700       710       720       730       

                                              400       410        
pF1KB3 ---------------------------------------KEEPVEALTFSREHGPGVAEP
                                              :::::::::::::::::::::
NP_996 SGVHRRRPIHHHVGKGPVFVKPKNTQPVAKSTHPPPLPAKEEPVEALTFSREHGPGVAEP
       740       750       760       770       780       790       

      420       430       440       450       460       470        
pF1KB3 EVATAPPEKEIPSLDQEKTKLEPGQPQLSPGISTIHLHPQFPVVIEKTSPPVPVEVAPEA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_996 EVATAPPEKEIPSLDQEKTKLEPGQPQLSPGISTIHLHPQFPVVIEKTSPPVPVEVAPEA
       800       810       820       830       840       850       

      480       490       500       510       520       530        
pF1KB3 STSSASQVIAPTQVTEINECTVNPDICGAGHCINLPVRYTCICYEGYRFSEQQRKCVDID
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_996 STSSASQVIAPTQVTEINECTVNPDICGAGHCINLPVRYTCICYEGYRFSEQQRKCVDID
       860       870       880       890       900       910       

      540       550       560       570       580       590        
pF1KB3 ECTQVQHLCSQGRCENTEGSFLCICPAGFMASEEGTNCIDVDECLRPDVCGEGHCVNTVG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_996 ECTQVQHLCSQGRCENTEGSFLCICPAGFMASEEGTNCIDVDECLRPDVCGEGHCVNTVG
       920       930       940       950       960       970       

      600       610       620       630       640       650        
pF1KB3 AFRCEYCDSGYRMTQRGRCEDIDECLNPSTCPDEQCVNSPGSYQCVPCTEGFRGWNGQCL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_996 AFRCEYCDSGYRMTQRGRCEDIDECLNPSTCPDEQCVNSPGSYQCVPCTEGFRGWNGQCL
       980       990      1000      1010      1020      1030       

      660       670       680       690       700       710        
pF1KB3 DVDECLEPNVCANGDCSNLEGSYMCSCHKGYTRTPDHKHCRDIDECQQGNLCVNGQCKNT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_996 DVDECLEPNVCANGDCSNLEGSYMCSCHKGYTRTPDHKHCRDIDECQQGNLCVNGQCKNT
      1040      1050      1060      1070      1080      1090       

      720       730       740       750       760       770        
pF1KB3 EGSFRCTCGQGYQLSAAKDQCEDIDECQHRHLCAHGQCRNTEGSFQCVCDQGYRASGLGD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_996 EGSFRCTCGQGYQLSAAKDQCEDIDECQHRHLCAHGQCRNTEGSFQCVCDQGYRASGLGD
      1100      1110      1120      1130      1140      1150       

      780       790       800       810       820       830        
pF1KB3 HCEDINECLEDKSVCQRGDCINTAGSYDCTCPDGFQLDDNKTCQDINECEHPGLCGPQGE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_996 HCEDINECLEDKSVCQRGDCINTAGSYDCTCPDGFQLDDNKTCQDINECEHPGLCGPQGE
      1160      1170      1180      1190      1200      1210       

      840       850       860       870       880       890        
pF1KB3 CLNTEGSFHCVCQQGFSISADGRTCEDIDECVNNTVCDSHGFCDNTAGSFRCLCYQGFQA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_996 CLNTEGSFHCVCQQGFSISADGRTCEDIDECVNNTVCDSHGFCDNTAGSFRCLCYQGFQA
      1220      1230      1240      1250      1260      1270       

      900       910       920       930       940       950        
pF1KB3 PQDGQGCVDVNECELLSGVCGEAFCENVEGSFLCVCADENQEYSPMTGQCRSRTSTDLDV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_996 PQDGQGCVDVNECELLSGVCGEAFCENVEGSFLCVCADENQEYSPMTGQCRSRTSTDLDV
      1280      1290      1300      1310      1320      1330       

      960       970       980       990      1000      1010        
pF1KB3 DVDQPKEEKKECYYNLNDASLCDNVLAPNVTKQECCCTSGAGWGDNCEIFPCPVLGTAEF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_996 DVDQPKEEKKECYYNLNDASLCDNVLAPNVTKQECCCTSGAGWGDNCEIFPCPVLGTAEF
      1340      1350      1360      1370      1380      1390       

     1020      1030      1040      1050      1060      1070        
pF1KB3 TEMCPKGKGFVPAGESSSEAGGENYKDADECLLFGQEICKNGFCLNTRPGYECYCKQGTY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_996 TEMCPKGKGFVPAGESSSEAGGENYKDADECLLFGQEICKNGFCLNTRPGYECYCKQGTY
      1400      1410      1420      1430      1440      1450       

     1080      1090      1100      1110      1120      1130        
pF1KB3 YDPVKLQCFDMDECQDPSSCIDGQCVNTEGSYNCFCTHPMVLDASEKRCIRPAESNEQIE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_996 YDPVKLQCFDMDECQDPSSCIDGQCVNTEGSYNCFCTHPMVLDASEKRCIRPAESNEQIE
      1460      1470      1480      1490      1500      1510       

     1140      1150      1160      1170      1180      1190        
pF1KB3 ETDVYQDLCWEHLSDEYVCSRPLVGKQTTYTECCCLYGEAWGMQCALCPLKDSDDYAQLC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_996 ETDVYQDLCWEHLSDEYVCSRPLVGKQTTYTECCCLYGEAWGMQCALCPLKDSDDYAQLC
      1520      1530      1540      1550      1560      1570       

     1200      1210      1220      1230      1240      1250        
pF1KB3 NIPVTGRRQPYGRDALVDFSEQYTPEADPYFIQDRFLNSFEELQAEECGILNGCENGRCV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_996 NIPVTGRRQPYGRDALVDFSEQYTPEADPYFIQDRFLNSFEELQAEECGILNGCENGRCV
      1580      1590      1600      1610      1620      1630       

     1260      1270      1280      1290      1300      1310        
pF1KB3 RVQEGYTCDCFDGYHLDTAKMTCVDVNECDELNNRMSLCKNAKCINTDGSYKCLCLPGYV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_996 RVQEGYTCDCFDGYHLDTAKMTCVDVNECDELNNRMSLCKNAKCINTDGSYKCLCLPGYV
      1640      1650      1660      1670      1680      1690       

     1320      1330      1340  
pF1KB3 PSDKPNYCTPLNTALNLEKDSDLE
       ::::::::::::::::::::::::
NP_996 PSDKPNYCTPLNTALNLEKDSDLE
      1700      1710      1720 

>>XP_011531162 (OMIM: 150390) PREDICTED: latent-transfor  (1666 aa)
 initn: 8948 init1: 6585 opt: 7080  Z-score: 4555.5  bits: 855.6 E(85289):    0
Smith-Waterman score: 9264; 95.7% identity (95.9% similar) in 1322 aa overlap (75-1342:345-1666)

           50        60        70        80        90       100    
pF1KB3 QNSCEKGNTTTLISENGHAADTLTATNFRVVICHLPCMNGGQCSSRDKCQCPPNFTGKLC
                                     .:::::::::::::::::::::::::::::
XP_011 PAQKGISGEQSTEGSFPLRYVQDQVAAPFQLICHLPCMNGGQCSSRDKCQCPPNFTGKLC
          320       330       340       350       360       370    

          110       120       130       140       150       160    
pF1KB3 QIPVHGASVPKLYQHSQQPGKALGTHVIHSTHTLPLTVTSQQGVKVKFPPNIVNIHVKHP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QIPVHGASVPKLYQHSQQPGKALGTHVIHSTHTLPLTVTSQQGVKVKFPPNIVNIHVKHP
          380       390       400       410       420       430    

          170       180       190       200       210       220    
pF1KB3 PEASVQIHQVSRIDGPTGQKTKEAQPGQSQVSYQGLPVQKTQTIHSTYSHQQVIPHVYPV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PEASVQIHQVSRIDGPTGQKTKEAQPGQSQVSYQGLPVQKTQTIHSTYSHQQVIPHVYPV
          440       450       460       470       480       490    

          230       240       250       260       270       280    
pF1KB3 AAKTQLGRCFQETIGSQCGKALPGLSKQEDCCGTVGTSWGFNKCQKCPKKPSYHGYNQMM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AAKTQLGRCFQETIGSQCGKALPGLSKQEDCCGTVGTSWGFNKCQKCPKKPSYHGYNQMM
          500       510       520       530       540       550    

          290       300       310       320       330       340    
pF1KB3 ECLPGYKRVNNTFCQDINECQLQGVCPNGECLNTMGSYRCTCKIGFGPDPTFSSCVPDPP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ECLPGYKRVNNTFCQDINECQLQGVCPNGECLNTMGSYRCTCKIGFGPDPTFSSCVPDPP
          560       570       580       590       600       610    

          350       360       370       380       390              
pF1KB3 VISEEKGPCYRLVSSGRQCMHPLSVHLTKQLCCCSVGKAWGPHCEKCPLPGTA-------
       :::::::::::::::::::::::::::::::::::::::::::::::::::::       
XP_011 VISEEKGPCYRLVSSGRQCMHPLSVHLTKQLCCCSVGKAWGPHCEKCPLPGTAAFKEICP
          620       630       640       650       660       670    

                                                     400       410 
pF1KB3 ----------------------------------------------KEEPVEALTFSREH
                                                     ::::::::::::::
XP_011 GGMGYTVSGVHRRRPIHHHVGKGPVFVKPKNTQPVAKSTHPPPLPAKEEPVEALTFSREH
          680       690       700       710       720       730    

             420       430       440       450       460        470
pF1KB3 GPGVAEPEVATAPPEKEIPSLDQEKTKLEPGQPQLSPGISTIHLHPQFP-VVIEKTSPPV
       ::::::::::::::::::::::::::::::::::::::::::::::::: .:::::::::
XP_011 GPGVAEPEVATAPPEKEIPSLDQEKTKLEPGQPQLSPGISTIHLHPQFPGIVIEKTSPPV
          740       750       760       770       780       790    

              480       490       500       510       520       530
pF1KB3 PVEVAPEASTSSASQVIAPTQVTEINECTVNPDICGAGHCINLPVRYTCICYEGYRFSEQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PVEVAPEASTSSASQVIAPTQVTEINECTVNPDICGAGHCINLPVRYTCICYEGYRFSEQ
          800       810       820       830       840       850    

              540       550       560       570       580       590
pF1KB3 QRKCVDIDECTQVQHLCSQGRCENTEGSFLCICPAGFMASEEGTNCIDVDECLRPDVCGE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QRKCVDIDECTQVQHLCSQGRCENTEGSFLCICPAGFMASEEGTNCIDVDECLRPDVCGE
          860       870       880       890       900       910    

              600       610       620       630       640       650
pF1KB3 GHCVNTVGAFRCEYCDSGYRMTQRGRCEDIDECLNPSTCPDEQCVNSPGSYQCVPCTEGF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GHCVNTVGAFRCEYCDSGYRMTQRGRCEDIDECLNPSTCPDEQCVNSPGSYQCVPCTEGF
          920       930       940       950       960       970    

              660       670       680       690       700       710
pF1KB3 RGWNGQCLDVDECLEPNVCANGDCSNLEGSYMCSCHKGYTRTPDHKHCRDIDECQQGNLC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RGWNGQCLDVDECLEPNVCANGDCSNLEGSYMCSCHKGYTRTPDHKHCRDIDECQQGNLC
          980       990      1000      1010      1020      1030    

              720       730       740       750       760       770
pF1KB3 VNGQCKNTEGSFRCTCGQGYQLSAAKDQCEDIDECQHRHLCAHGQCRNTEGSFQCVCDQG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VNGQCKNTEGSFRCTCGQGYQLSAAKDQCEDIDECQHRHLCAHGQCRNTEGSFQCVCDQG
         1040      1050      1060      1070      1080      1090    

              780       790       800       810       820       830
pF1KB3 YRASGLGDHCEDINECLEDKSVCQRGDCINTAGSYDCTCPDGFQLDDNKTCQDINECEHP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YRASGLGDHCEDINECLEDKSVCQRGDCINTAGSYDCTCPDGFQLDDNKTCQDINECEHP
         1100      1110      1120      1130      1140      1150    

              840       850       860       870       880       890
pF1KB3 GLCGPQGECLNTEGSFHCVCQQGFSISADGRTCEDIDECVNNTVCDSHGFCDNTAGSFRC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GLCGPQGECLNTEGSFHCVCQQGFSISADGRTCEDIDECVNNTVCDSHGFCDNTAGSFRC
         1160      1170      1180      1190      1200      1210    

              900       910       920       930       940       950
pF1KB3 LCYQGFQAPQDGQGCVDVNECELLSGVCGEAFCENVEGSFLCVCADENQEYSPMTGQCRS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LCYQGFQAPQDGQGCVDVNECELLSGVCGEAFCENVEGSFLCVCADENQEYSPMTGQCRS
         1220      1230      1240      1250      1260      1270    

              960       970       980       990      1000      1010
pF1KB3 RTSTDLDVDVDQPKEEKKECYYNLNDASLCDNVLAPNVTKQECCCTSGAGWGDNCEIFPC
       ::::::::::::::::::::::::::::::::::::::::::::::::.:::::::::::
XP_011 RTSTDLDVDVDQPKEEKKECYYNLNDASLCDNVLAPNVTKQECCCTSGVGWGDNCEIFPC
         1280      1290      1300      1310      1320      1330    

             1020      1030      1040      1050      1060      1070
pF1KB3 PVLGTAEFTEMCPKGKGFVPAGESSSEAGGENYKDADECLLFGQEICKNGFCLNTRPGYE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PVLGTAEFTEMCPKGKGFVPAGESSSEAGGENYKDADECLLFGQEICKNGFCLNTRPGYE
         1340      1350      1360      1370      1380      1390    

             1080      1090      1100      1110      1120      1130
pF1KB3 CYCKQGTYYDPVKLQCFDMDECQDPSSCIDGQCVNTEGSYNCFCTHPMVLDASEKRCIRP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CYCKQGTYYDPVKLQCFDMDECQDPSSCIDGQCVNTEGSYNCFCTHPMVLDASEKRCIRP
         1400      1410      1420      1430      1440      1450    

             1140      1150      1160      1170      1180      1190
pF1KB3 AESNEQIEETDVYQDLCWEHLSDEYVCSRPLVGKQTTYTECCCLYGEAWGMQCALCPLKD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AESNEQIEETDVYQDLCWEHLSDEYVCSRPLVGKQTTYTECCCLYGEAWGMQCALCPLKD
         1460      1470      1480      1490      1500      1510    

             1200      1210      1220      1230      1240      1250
pF1KB3 SDDYAQLCNIPVTGRRQPYGRDALVDFSEQYTPEADPYFIQDRFLNSFEELQAEECGILN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SDDYAQLCNIPVTGRRQPYGRDALVDFSEQYTPEADPYFIQDRFLNSFEELQAEECGILN
         1520      1530      1540      1550      1560      1570    

             1260      1270      1280      1290      1300      1310
pF1KB3 GCENGRCVRVQEGYTCDCFDGYHLDTAKMTCVDVNECDELNNRMSLCKNAKCINTDGSYK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GCENGRCVRVQEGYTCDCFDGYHLDTAKMTCVDVNECDELNNRMSLCKNAKCINTDGSYK
         1580      1590      1600      1610      1620      1630    

             1320      1330      1340  
pF1KB3 CLCLPGYVPSDKPNYCTPLNTALNLEKDSDLE
       ::::::::::::::::::::::::::::::::
XP_011 CLCLPGYVPSDKPNYCTPLNTALNLEKDSDLE
         1640      1650      1660      

>>XP_011531155 (OMIM: 150390) PREDICTED: latent-transfor  (1722 aa)
 initn: 9327 init1: 6585 opt: 7080  Z-score: 4555.4  bits: 855.6 E(85289):    0
Smith-Waterman score: 9611; 95.9% identity (96.1% similar) in 1374 aa overlap (23-1342:349-1722)

                       10        20        30        40        50  
pF1KB3         MDTKLMCLLFFFSLPPLLVSNHTGRIKVVFTPSICKVTCTKGSCQNSCEKGN
                                     ::::::::::::::::::::::::::::::
XP_011 GISGEQSTEGSFPLRYVQDQVAAPFQLSNHTGRIKVVFTPSICKVTCTKGSCQNSCEKGN
      320       330       340       350       360       370        

             60        70        80        90       100       110  
pF1KB3 TTTLISENGHAADTLTATNFRVVICHLPCMNGGQCSSRDKCQCPPNFTGKLCQIPVHGAS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TTTLISENGHAADTLTATNFRVVICHLPCMNGGQCSSRDKCQCPPNFTGKLCQIPVHGAS
      380       390       400       410       420       430        

            120       130       140       150       160       170  
pF1KB3 VPKLYQHSQQPGKALGTHVIHSTHTLPLTVTSQQGVKVKFPPNIVNIHVKHPPEASVQIH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VPKLYQHSQQPGKALGTHVIHSTHTLPLTVTSQQGVKVKFPPNIVNIHVKHPPEASVQIH
      440       450       460       470       480       490        

            180       190       200       210       220       230  
pF1KB3 QVSRIDGPTGQKTKEAQPGQSQVSYQGLPVQKTQTIHSTYSHQQVIPHVYPVAAKTQLGR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QVSRIDGPTGQKTKEAQPGQSQVSYQGLPVQKTQTIHSTYSHQQVIPHVYPVAAKTQLGR
      500       510       520       530       540       550        

            240       250       260       270       280       290  
pF1KB3 CFQETIGSQCGKALPGLSKQEDCCGTVGTSWGFNKCQKCPKKPSYHGYNQMMECLPGYKR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CFQETIGSQCGKALPGLSKQEDCCGTVGTSWGFNKCQKCPKKPSYHGYNQMMECLPGYKR
      560       570       580       590       600       610        

            300       310       320       330       340       350  
pF1KB3 VNNTFCQDINECQLQGVCPNGECLNTMGSYRCTCKIGFGPDPTFSSCVPDPPVISEEKGP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VNNTFCQDINECQLQGVCPNGECLNTMGSYRCTCKIGFGPDPTFSSCVPDPPVISEEKGP
      620       630       640       650       660       670        

            360       370       380       390                      
pF1KB3 CYRLVSSGRQCMHPLSVHLTKQLCCCSVGKAWGPHCEKCPLPGTA---------------
       :::::::::::::::::::::::::::::::::::::::::::::               
XP_011 CYRLVSSGRQCMHPLSVHLTKQLCCCSVGKAWGPHCEKCPLPGTAAFKEICPGGMGYTVS
      680       690       700       710       720       730        

                                             400       410         
pF1KB3 --------------------------------------KEEPVEALTFSREHGPGVAEPE
                                             ::::::::::::::::::::::
XP_011 GVHRRRPIHHHVGKGPVFVKPKNTQPVAKSTHPPPLPAKEEPVEALTFSREHGPGVAEPE
      740       750       760       770       780       790        

     420       430       440       450       460        470        
pF1KB3 VATAPPEKEIPSLDQEKTKLEPGQPQLSPGISTIHLHPQFP-VVIEKTSPPVPVEVAPEA
       ::::::::::::::::::::::::::::::::::::::::: .:::::::::::::::::
XP_011 VATAPPEKEIPSLDQEKTKLEPGQPQLSPGISTIHLHPQFPGIVIEKTSPPVPVEVAPEA
      800       810       820       830       840       850        

      480       490       500       510       520       530        
pF1KB3 STSSASQVIAPTQVTEINECTVNPDICGAGHCINLPVRYTCICYEGYRFSEQQRKCVDID
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 STSSASQVIAPTQVTEINECTVNPDICGAGHCINLPVRYTCICYEGYRFSEQQRKCVDID
      860       870       880       890       900       910        

      540       550       560       570       580       590        
pF1KB3 ECTQVQHLCSQGRCENTEGSFLCICPAGFMASEEGTNCIDVDECLRPDVCGEGHCVNTVG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ECTQVQHLCSQGRCENTEGSFLCICPAGFMASEEGTNCIDVDECLRPDVCGEGHCVNTVG
      920       930       940       950       960       970        

      600       610       620       630       640       650        
pF1KB3 AFRCEYCDSGYRMTQRGRCEDIDECLNPSTCPDEQCVNSPGSYQCVPCTEGFRGWNGQCL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AFRCEYCDSGYRMTQRGRCEDIDECLNPSTCPDEQCVNSPGSYQCVPCTEGFRGWNGQCL
      980       990      1000      1010      1020      1030        

      660       670       680       690       700       710        
pF1KB3 DVDECLEPNVCANGDCSNLEGSYMCSCHKGYTRTPDHKHCRDIDECQQGNLCVNGQCKNT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DVDECLEPNVCANGDCSNLEGSYMCSCHKGYTRTPDHKHCRDIDECQQGNLCVNGQCKNT
     1040      1050      1060      1070      1080      1090        

      720       730       740       750       760       770        
pF1KB3 EGSFRCTCGQGYQLSAAKDQCEDIDECQHRHLCAHGQCRNTEGSFQCVCDQGYRASGLGD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EGSFRCTCGQGYQLSAAKDQCEDIDECQHRHLCAHGQCRNTEGSFQCVCDQGYRASGLGD
     1100      1110      1120      1130      1140      1150        

      780       790       800       810       820       830        
pF1KB3 HCEDINECLEDKSVCQRGDCINTAGSYDCTCPDGFQLDDNKTCQDINECEHPGLCGPQGE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HCEDINECLEDKSVCQRGDCINTAGSYDCTCPDGFQLDDNKTCQDINECEHPGLCGPQGE
     1160      1170      1180      1190      1200      1210        

      840       850       860       870       880       890        
pF1KB3 CLNTEGSFHCVCQQGFSISADGRTCEDIDECVNNTVCDSHGFCDNTAGSFRCLCYQGFQA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CLNTEGSFHCVCQQGFSISADGRTCEDIDECVNNTVCDSHGFCDNTAGSFRCLCYQGFQA
     1220      1230      1240      1250      1260      1270        

      900       910       920       930       940       950        
pF1KB3 PQDGQGCVDVNECELLSGVCGEAFCENVEGSFLCVCADENQEYSPMTGQCRSRTSTDLDV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PQDGQGCVDVNECELLSGVCGEAFCENVEGSFLCVCADENQEYSPMTGQCRSRTSTDLDV
     1280      1290      1300      1310      1320      1330        

      960       970       980       990      1000      1010        
pF1KB3 DVDQPKEEKKECYYNLNDASLCDNVLAPNVTKQECCCTSGAGWGDNCEIFPCPVLGTAEF
       ::::::::::::::::::::::::::::::::::::::::.:::::::::::::::::::
XP_011 DVDQPKEEKKECYYNLNDASLCDNVLAPNVTKQECCCTSGVGWGDNCEIFPCPVLGTAEF
     1340      1350      1360      1370      1380      1390        

     1020      1030      1040      1050      1060      1070        
pF1KB3 TEMCPKGKGFVPAGESSSEAGGENYKDADECLLFGQEICKNGFCLNTRPGYECYCKQGTY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TEMCPKGKGFVPAGESSSEAGGENYKDADECLLFGQEICKNGFCLNTRPGYECYCKQGTY
     1400      1410      1420      1430      1440      1450        

     1080      1090      1100      1110      1120      1130        
pF1KB3 YDPVKLQCFDMDECQDPSSCIDGQCVNTEGSYNCFCTHPMVLDASEKRCIRPAESNEQIE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YDPVKLQCFDMDECQDPSSCIDGQCVNTEGSYNCFCTHPMVLDASEKRCIRPAESNEQIE
     1460      1470      1480      1490      1500      1510        

     1140      1150      1160      1170      1180      1190        
pF1KB3 ETDVYQDLCWEHLSDEYVCSRPLVGKQTTYTECCCLYGEAWGMQCALCPLKDSDDYAQLC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ETDVYQDLCWEHLSDEYVCSRPLVGKQTTYTECCCLYGEAWGMQCALCPLKDSDDYAQLC
     1520      1530      1540      1550      1560      1570        

     1200      1210      1220      1230      1240      1250        
pF1KB3 NIPVTGRRQPYGRDALVDFSEQYTPEADPYFIQDRFLNSFEELQAEECGILNGCENGRCV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NIPVTGRRQPYGRDALVDFSEQYTPEADPYFIQDRFLNSFEELQAEECGILNGCENGRCV
     1580      1590      1600      1610      1620      1630        

     1260      1270      1280      1290      1300      1310        
pF1KB3 RVQEGYTCDCFDGYHLDTAKMTCVDVNECDELNNRMSLCKNAKCINTDGSYKCLCLPGYV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RVQEGYTCDCFDGYHLDTAKMTCVDVNECDELNNRMSLCKNAKCINTDGSYKCLCLPGYV
     1640      1650      1660      1670      1680      1690        

     1320      1330      1340  
pF1KB3 PSDKPNYCTPLNTALNLEKDSDLE
       ::::::::::::::::::::::::
XP_011 PSDKPNYCTPLNTALNLEKDSDLE
     1700      1710      1720  

>>XP_011531157 (OMIM: 150390) PREDICTED: latent-transfor  (1720 aa)
 initn: 9323 init1: 6581 opt: 7075  Z-score: 4552.1  bits: 855.0 E(85289):    0
Smith-Waterman score: 9624; 96.0% identity (96.1% similar) in 1375 aa overlap (21-1342:347-1720)

                         10        20        30        40        50
pF1KB3           MDTKLMCLLFFFSLPPLLVSNHTGRIKVVFTPSICKVTCTKGSCQNSCEK
                                     ::::::::::::::::::::::::::::::
XP_011 QKGISGEQSTEGSFPLRYVQDQVAAPFQLSNHTGRIKVVFTPSICKVTCTKGSCQNSCEK
        320       330       340       350       360       370      

               60        70        80        90       100       110
pF1KB3 GNTTTLISENGHAADTLTATNFRVVICHLPCMNGGQCSSRDKCQCPPNFTGKLCQIPVHG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GNTTTLISENGHAADTLTATNFRVVICHLPCMNGGQCSSRDKCQCPPNFTGKLCQIPVHG
        380       390       400       410       420       430      

              120       130       140       150       160       170
pF1KB3 ASVPKLYQHSQQPGKALGTHVIHSTHTLPLTVTSQQGVKVKFPPNIVNIHVKHPPEASVQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ASVPKLYQHSQQPGKALGTHVIHSTHTLPLTVTSQQGVKVKFPPNIVNIHVKHPPEASVQ
        440       450       460       470       480       490      

              180       190       200       210       220       230
pF1KB3 IHQVSRIDGPTGQKTKEAQPGQSQVSYQGLPVQKTQTIHSTYSHQQVIPHVYPVAAKTQL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IHQVSRIDGPTGQKTKEAQPGQSQVSYQGLPVQKTQTIHSTYSHQQVIPHVYPVAAKTQL
        500       510       520       530       540       550      

              240       250       260       270       280       290
pF1KB3 GRCFQETIGSQCGKALPGLSKQEDCCGTVGTSWGFNKCQKCPKKPSYHGYNQMMECLPGY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GRCFQETIGSQCGKALPGLSKQEDCCGTVGTSWGFNKCQKCPKKPSYHGYNQMMECLPGY
        560       570       580       590       600       610      

              300       310       320       330       340       350
pF1KB3 KRVNNTFCQDINECQLQGVCPNGECLNTMGSYRCTCKIGFGPDPTFSSCVPDPPVISEEK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KRVNNTFCQDINECQLQGVCPNGECLNTMGSYRCTCKIGFGPDPTFSSCVPDPPVISEEK
        620       630       640       650       660       670      

              360       370       380       390                    
pF1KB3 GPCYRLVSSGRQCMHPLSVHLTKQLCCCSVGKAWGPHCEKCPLPGTA-------------
       :::::::::::::::::::::::::::::::::::::::::::::::             
XP_011 GPCYRLVSSGRQCMHPLSVHLTKQLCCCSVGKAWGPHCEKCPLPGTAAFKEICPGGMGYT
        680       690       700       710       720       730      

                                               400       410       
pF1KB3 ----------------------------------------KEEPVEALTFSREHGPGVAE
                                               ::::::::::::::::::::
XP_011 VSGVHRRRPIHHHVGKGPVFVKPKNTQPVAKSTHPPPLPAKEEPVEALTFSREHGPGVAE
        740       750       760       770       780       790      

       420       430       440       450       460       470       
pF1KB3 PEVATAPPEKEIPSLDQEKTKLEPGQPQLSPGISTIHLHPQFPVVIEKTSPPVPVEVAPE
       :::::::::::::::::::::::::::::::::::::::::::: :::::::::::::::
XP_011 PEVATAPPEKEIPSLDQEKTKLEPGQPQLSPGISTIHLHPQFPV-IEKTSPPVPVEVAPE
        800       810       820       830       840        850     

       480       490       500       510       520       530       
pF1KB3 ASTSSASQVIAPTQVTEINECTVNPDICGAGHCINLPVRYTCICYEGYRFSEQQRKCVDI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ASTSSASQVIAPTQVTEINECTVNPDICGAGHCINLPVRYTCICYEGYRFSEQQRKCVDI
         860       870       880       890       900       910     

       540       550       560       570       580       590       
pF1KB3 DECTQVQHLCSQGRCENTEGSFLCICPAGFMASEEGTNCIDVDECLRPDVCGEGHCVNTV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DECTQVQHLCSQGRCENTEGSFLCICPAGFMASEEGTNCIDVDECLRPDVCGEGHCVNTV
         920       930       940       950       960       970     

       600       610       620       630       640       650       
pF1KB3 GAFRCEYCDSGYRMTQRGRCEDIDECLNPSTCPDEQCVNSPGSYQCVPCTEGFRGWNGQC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GAFRCEYCDSGYRMTQRGRCEDIDECLNPSTCPDEQCVNSPGSYQCVPCTEGFRGWNGQC
         980       990      1000      1010      1020      1030     

       660       670       680       690       700       710       
pF1KB3 LDVDECLEPNVCANGDCSNLEGSYMCSCHKGYTRTPDHKHCRDIDECQQGNLCVNGQCKN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LDVDECLEPNVCANGDCSNLEGSYMCSCHKGYTRTPDHKHCRDIDECQQGNLCVNGQCKN
        1040      1050      1060      1070      1080      1090     

       720       730       740       750       760       770       
pF1KB3 TEGSFRCTCGQGYQLSAAKDQCEDIDECQHRHLCAHGQCRNTEGSFQCVCDQGYRASGLG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TEGSFRCTCGQGYQLSAAKDQCEDIDECQHRHLCAHGQCRNTEGSFQCVCDQGYRASGLG
        1100      1110      1120      1130      1140      1150     

       780       790       800       810       820       830       
pF1KB3 DHCEDINECLEDKSVCQRGDCINTAGSYDCTCPDGFQLDDNKTCQDINECEHPGLCGPQG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DHCEDINECLEDKSVCQRGDCINTAGSYDCTCPDGFQLDDNKTCQDINECEHPGLCGPQG
        1160      1170      1180      1190      1200      1210     

       840       850       860       870       880       890       
pF1KB3 ECLNTEGSFHCVCQQGFSISADGRTCEDIDECVNNTVCDSHGFCDNTAGSFRCLCYQGFQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ECLNTEGSFHCVCQQGFSISADGRTCEDIDECVNNTVCDSHGFCDNTAGSFRCLCYQGFQ
        1220      1230      1240      1250      1260      1270     

       900       910       920       930       940       950       
pF1KB3 APQDGQGCVDVNECELLSGVCGEAFCENVEGSFLCVCADENQEYSPMTGQCRSRTSTDLD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 APQDGQGCVDVNECELLSGVCGEAFCENVEGSFLCVCADENQEYSPMTGQCRSRTSTDLD
        1280      1290      1300      1310      1320      1330     

       960       970       980       990      1000      1010       
pF1KB3 VDVDQPKEEKKECYYNLNDASLCDNVLAPNVTKQECCCTSGAGWGDNCEIFPCPVLGTAE
       :::::::::::::::::::::::::::::::::::::::::.::::::::::::::::::
XP_011 VDVDQPKEEKKECYYNLNDASLCDNVLAPNVTKQECCCTSGVGWGDNCEIFPCPVLGTAE
        1340      1350      1360      1370      1380      1390     

      1020      1030      1040      1050      1060      1070       
pF1KB3 FTEMCPKGKGFVPAGESSSEAGGENYKDADECLLFGQEICKNGFCLNTRPGYECYCKQGT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FTEMCPKGKGFVPAGESSSEAGGENYKDADECLLFGQEICKNGFCLNTRPGYECYCKQGT
        1400      1410      1420      1430      1440      1450     

      1080      1090      1100      1110      1120      1130       
pF1KB3 YYDPVKLQCFDMDECQDPSSCIDGQCVNTEGSYNCFCTHPMVLDASEKRCIRPAESNEQI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YYDPVKLQCFDMDECQDPSSCIDGQCVNTEGSYNCFCTHPMVLDASEKRCIRPAESNEQI
        1460      1470      1480      1490      1500      1510     

      1140      1150      1160      1170      1180      1190       
pF1KB3 EETDVYQDLCWEHLSDEYVCSRPLVGKQTTYTECCCLYGEAWGMQCALCPLKDSDDYAQL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EETDVYQDLCWEHLSDEYVCSRPLVGKQTTYTECCCLYGEAWGMQCALCPLKDSDDYAQL
        1520      1530      1540      1550      1560      1570     

      1200      1210      1220      1230      1240      1250       
pF1KB3 CNIPVTGRRQPYGRDALVDFSEQYTPEADPYFIQDRFLNSFEELQAEECGILNGCENGRC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CNIPVTGRRQPYGRDALVDFSEQYTPEADPYFIQDRFLNSFEELQAEECGILNGCENGRC
        1580      1590      1600      1610      1620      1630     

      1260      1270      1280      1290      1300      1310       
pF1KB3 VRVQEGYTCDCFDGYHLDTAKMTCVDVNECDELNNRMSLCKNAKCINTDGSYKCLCLPGY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VRVQEGYTCDCFDGYHLDTAKMTCVDVNECDELNNRMSLCKNAKCINTDGSYKCLCLPGY
        1640      1650      1660      1670      1680      1690     

      1320      1330      1340  
pF1KB3 VPSDKPNYCTPLNTALNLEKDSDLE
       :::::::::::::::::::::::::
XP_011 VPSDKPNYCTPLNTALNLEKDSDLE
        1700      1710      1720

>>NP_001159738 (OMIM: 150390) latent-transforming growth  (1300 aa)
 initn: 7334 init1: 6455 opt: 6602  Z-score: 4250.2  bits: 798.7 E(85289):    0
Smith-Waterman score: 9476; 96.9% identity (96.9% similar) in 1342 aa overlap (1-1342:1-1300)

               10        20        30        40        50        60
pF1KB3 MDTKLMCLLFFFSLPPLLVSNHTGRIKVVFTPSICKVTCTKGSCQNSCEKGNTTTLISEN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MDTKLMCLLFFFSLPPLLVSNHTGRIKVVFTPSICKVTCTKGSCQNSCEKGNTTTLISEN
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB3 GHAADTLTATNFRVVICHLPCMNGGQCSSRDKCQCPPNFTGKLCQIPVHGASVPKLYQHS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GHAADTLTATNFRVVICHLPCMNGGQCSSRDKCQCPPNFTGKLCQIPVHGASVPKLYQHS
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB3 QQPGKALGTHVIHSTHTLPLTVTSQQGVKVKFPPNIVNIHVKHPPEASVQIHQVSRIDGP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QQPGKALGTHVIHSTHTLPLTVTSQQGVKVKFPPNIVNIHVKHPPEASVQIHQVSRIDGP
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB3 TGQKTKEAQPGQSQVSYQGLPVQKTQTIHSTYSHQQVIPHVYPVAAKTQLGRCFQETIGS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TGQKTKEAQPGQSQVSYQGLPVQKTQTIHSTYSHQQVIPHVYPVAAKTQLGRCFQETIGS
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB3 QCGKALPGLSKQEDCCGTVGTSWGFNKCQKCPKKPSYHGYNQMMECLPGYKRVNNTFCQD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QCGKALPGLSKQEDCCGTVGTSWGFNKCQKCPKKPSYHGYNQMMECLPGYKRVNNTFCQD
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB3 INECQLQGVCPNGECLNTMGSYRCTCKIGFGPDPTFSSCVPDPPVISEEKGPCYRLVSSG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 INECQLQGVCPNGECLNTMGSYRCTCKIGFGPDPTFSSCVPDPPVISEEKGPCYRLVSSG
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB3 RQCMHPLSVHLTKQLCCCSVGKAWGPHCEKCPLPGTAKEEPVEALTFSREHGPGVAEPEV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RQCMHPLSVHLTKQLCCCSVGKAWGPHCEKCPLPGTAKEEPVEALTFSREHGPGVAEPEV
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KB3 ATAPPEKEIPSLDQEKTKLEPGQPQLSPGISTIHLHPQFPVVIEKTSPPVPVEVAPEAST
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ATAPPEKEIPSLDQEKTKLEPGQPQLSPGISTIHLHPQFPVVIEKTSPPVPVEVAPEAST
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KB3 SSASQVIAPTQVTEINECTVNPDICGAGHCINLPVRYTCICYEGYRFSEQQRKCVDIDEC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SSASQVIAPTQVTEINECTVNPDICGAGHCINLPVRYTCICYEGYRFSEQQRKCVDIDEC
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KB3 TQVQHLCSQGRCENTEGSFLCICPAGFMASEEGTNCIDVDECLRPDVCGEGHCVNTVGAF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TQVQHLCSQGRCENTEGSFLCICPAGFMASEEGTNCIDVDECLRPDVCGEGHCVNTVGAF
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KB3 RCEYCDSGYRMTQRGRCEDIDECLNPSTCPDEQCVNSPGSYQCVPCTEGFRGWNGQCLDV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RCEYCDSGYRMTQRGRCEDIDECLNPSTCPDEQCVNSPGSYQCVPCTEGFRGWNGQCLDV
              610       620       630       640       650       660

              670       680       690       700       710       720
pF1KB3 DECLEPNVCANGDCSNLEGSYMCSCHKGYTRTPDHKHCRDIDECQQGNLCVNGQCKNTEG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DECLEPNVCANGDCSNLEGSYMCSCHKGYTRTPDHKHCRDIDECQQGNLCVNGQCKNTEG
              670       680       690       700       710       720

              730       740       750       760       770       780
pF1KB3 SFRCTCGQGYQLSAAKDQCEDIDECQHRHLCAHGQCRNTEGSFQCVCDQGYRASGLGDHC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SFRCTCGQGYQLSAAKDQCEDIDECQHRHLCAHGQCRNTEGSFQCVCDQGYRASGLGDHC
              730       740       750       760       770       780

              790       800       810       820       830       840
pF1KB3 EDINECLEDKSVCQRGDCINTAGSYDCTCPDGFQLDDNKTCQDINECEHPGLCGPQGECL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EDINECLEDKSVCQRGDCINTAGSYDCTCPDGFQLDDNKTCQDINECEHPGLCGPQGECL
              790       800       810       820       830       840

              850       860       870       880       890       900
pF1KB3 NTEGSFHCVCQQGFSISADGRTCEDIDECVNNTVCDSHGFCDNTAGSFRCLCYQGFQAPQ
       :::::::::::::::::::::::::                                   
NP_001 NTEGSFHCVCQQGFSISADGRTCED-----------------------------------
              850       860                                        

              910       920       930       940       950       960
pF1KB3 DGQGCVDVNECELLSGVCGEAFCENVEGSFLCVCADENQEYSPMTGQCRSRTSTDLDVDV
              :::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 -------VNECELLSGVCGEAFCENVEGSFLCVCADENQEYSPMTGQCRSRTSTDLDVDV
                870       880       890       900       910        

              970       980       990      1000      1010      1020
pF1KB3 DQPKEEKKECYYNLNDASLCDNVLAPNVTKQECCCTSGAGWGDNCEIFPCPVLGTAEFTE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DQPKEEKKECYYNLNDASLCDNVLAPNVTKQECCCTSGAGWGDNCEIFPCPVLGTAEFTE
      920       930       940       950       960       970        

             1030      1040      1050      1060      1070      1080
pF1KB3 MCPKGKGFVPAGESSSEAGGENYKDADECLLFGQEICKNGFCLNTRPGYECYCKQGTYYD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MCPKGKGFVPAGESSSEAGGENYKDADECLLFGQEICKNGFCLNTRPGYECYCKQGTYYD
      980       990      1000      1010      1020      1030        

             1090      1100      1110      1120      1130      1140
pF1KB3 PVKLQCFDMDECQDPSSCIDGQCVNTEGSYNCFCTHPMVLDASEKRCIRPAESNEQIEET
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PVKLQCFDMDECQDPSSCIDGQCVNTEGSYNCFCTHPMVLDASEKRCIRPAESNEQIEET
     1040      1050      1060      1070      1080      1090        

             1150      1160      1170      1180      1190      1200
pF1KB3 DVYQDLCWEHLSDEYVCSRPLVGKQTTYTECCCLYGEAWGMQCALCPLKDSDDYAQLCNI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DVYQDLCWEHLSDEYVCSRPLVGKQTTYTECCCLYGEAWGMQCALCPLKDSDDYAQLCNI
     1100      1110      1120      1130      1140      1150        

             1210      1220      1230      1240      1250      1260
pF1KB3 PVTGRRQPYGRDALVDFSEQYTPEADPYFIQDRFLNSFEELQAEECGILNGCENGRCVRV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PVTGRRQPYGRDALVDFSEQYTPEADPYFIQDRFLNSFEELQAEECGILNGCENGRCVRV
     1160      1170      1180      1190      1200      1210        

             1270      1280      1290      1300      1310      1320
pF1KB3 QEGYTCDCFDGYHLDTAKMTCVDVNECDELNNRMSLCKNAKCINTDGSYKCLCLPGYVPS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QEGYTCDCFDGYHLDTAKMTCVDVNECDELNNRMSLCKNAKCINTDGSYKCLCLPGYVPS
     1220      1230      1240      1250      1260      1270        

             1330      1340  
pF1KB3 DKPNYCTPLNTALNLEKDSDLE
       ::::::::::::::::::::::
NP_001 DKPNYCTPLNTALNLEKDSDLE
     1280      1290      1300

>>XP_005264375 (OMIM: 150390) PREDICTED: latent-transfor  (1626 aa)
 initn: 7204 init1: 6325 opt: 6482  Z-score: 4172.0  bits: 784.6 E(85289):    0
Smith-Waterman score: 9351; 96.5% identity (96.8% similar) in 1327 aa overlap (16-1342:342-1626)

                              10        20        30        40     
pF1KB3                MDTKLMCLLFFFSLPPLLVSNHTGRIKVVFTPSICKVTCTKGSCQ
                                     :. .::::::::::::::::::::::::::
XP_005 KYFPAQKGISGEQSTEGSFPLRYVQDQVAAPFQLSNHTGRIKVVFTPSICKVTCTKGSCQ
             320       330       340       350       360       370 

          50        60        70        80        90       100     
pF1KB3 NSCEKGNTTTLISENGHAADTLTATNFRVVICHLPCMNGGQCSSRDKCQCPPNFTGKLCQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 NSCEKGNTTTLISENGHAADTLTATNFRVVICHLPCMNGGQCSSRDKCQCPPNFTGKLCQ
             380       390       400       410       420       430 

         110       120       130       140       150       160     
pF1KB3 IPVHGASVPKLYQHSQQPGKALGTHVIHSTHTLPLTVTSQQGVKVKFPPNIVNIHVKHPP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 IPVHGASVPKLYQHSQQPGKALGTHVIHSTHTLPLTVTSQQGVKVKFPPNIVNIHVKHPP
             440       450       460       470       480       490 

         170       180       190       200       210       220     
pF1KB3 EASVQIHQVSRIDGPTGQKTKEAQPGQSQVSYQGLPVQKTQTIHSTYSHQQVIPHVYPVA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EASVQIHQVSRIDGPTGQKTKEAQPGQSQVSYQGLPVQKTQTIHSTYSHQQVIPHVYPVA
             500       510       520       530       540       550 

         230       240       250       260       270       280     
pF1KB3 AKTQLGRCFQETIGSQCGKALPGLSKQEDCCGTVGTSWGFNKCQKCPKKPSYHGYNQMME
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 AKTQLGRCFQETIGSQCGKALPGLSKQEDCCGTVGTSWGFNKCQKCPKKPSYHGYNQMME
             560       570       580       590       600       610 

         290       300       310       320       330       340     
pF1KB3 CLPGYKRVNNTFCQDINECQLQGVCPNGECLNTMGSYRCTCKIGFGPDPTFSSCVPDPPV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 CLPGYKRVNNTFCQDINECQLQGVCPNGECLNTMGSYRCTCKIGFGPDPTFSSCVPDPPV
             620       630       640       650       660       670 

         350       360       370       380       390       400     
pF1KB3 ISEEKGPCYRLVSSGRQCMHPLSVHLTKQLCCCSVGKAWGPHCEKCPLPGTAKEEPVEAL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ISEEKGPCYRLVSSGRQCMHPLSVHLTKQLCCCSVGKAWGPHCEKCPLPGTAKEEPVEAL
             680       690       700       710       720       730 

         410       420       430       440       450       460     
pF1KB3 TFSREHGPGVAEPEVATAPPEKEIPSLDQEKTKLEPGQPQLSPGISTIHLHPQFPVVIEK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TFSREHGPGVAEPEVATAPPEKEIPSLDQEKTKLEPGQPQLSPGISTIHLHPQFPVVIEK
             740       750       760       770       780       790 

         470       480       490       500       510       520     
pF1KB3 TSPPVPVEVAPEASTSSASQVIAPTQVTEINECTVNPDICGAGHCINLPVRYTCICYEGY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TSPPVPVEVAPEASTSSASQVIAPTQVTEINECTVNPDICGAGHCINLPVRYTCICYEGY
             800       810       820       830       840       850 

         530       540       550       560       570       580     
pF1KB3 RFSEQQRKCVDIDECTQVQHLCSQGRCENTEGSFLCICPAGFMASEEGTNCIDVDECLRP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RFSEQQRKCVDIDECTQVQHLCSQGRCENTEGSFLCICPAGFMASEEGTNCIDVDECLRP
             860       870       880       890       900       910 

         590       600       610       620       630       640     
pF1KB3 DVCGEGHCVNTVGAFRCEYCDSGYRMTQRGRCEDIDECLNPSTCPDEQCVNSPGSYQCVP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DVCGEGHCVNTVGAFRCEYCDSGYRMTQRGRCEDIDECLNPSTCPDEQCVNSPGSYQCVP
             920       930       940       950       960       970 

         650       660       670       680       690       700     
pF1KB3 CTEGFRGWNGQCLDVDECLEPNVCANGDCSNLEGSYMCSCHKGYTRTPDHKHCRDIDECQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 CTEGFRGWNGQCLDVDECLEPNVCANGDCSNLEGSYMCSCHKGYTRTPDHKHCRDIDECQ
             980       990      1000      1010      1020      1030 

         710       720       730       740       750       760     
pF1KB3 QGNLCVNGQCKNTEGSFRCTCGQGYQLSAAKDQCEDIDECQHRHLCAHGQCRNTEGSFQC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QGNLCVNGQCKNTEGSFRCTCGQGYQLSAAKDQCEDIDECQHRHLCAHGQCRNTEGSFQC
            1040      1050      1060      1070      1080      1090 

         770       780       790       800       810       820     
pF1KB3 VCDQGYRASGLGDHCEDINECLEDKSVCQRGDCINTAGSYDCTCPDGFQLDDNKTCQDIN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VCDQGYRASGLGDHCEDINECLEDKSVCQRGDCINTAGSYDCTCPDGFQLDDNKTCQDIN
            1100      1110      1120      1130      1140      1150 

         830       840       850       860       870       880     
pF1KB3 ECEHPGLCGPQGECLNTEGSFHCVCQQGFSISADGRTCEDIDECVNNTVCDSHGFCDNTA
       ::::::::::::::::::::::::::::::::::::::::                    
XP_005 ECEHPGLCGPQGECLNTEGSFHCVCQQGFSISADGRTCED--------------------
            1160      1170      1180      1190                     

         890       900       910       920       930       940     
pF1KB3 GSFRCLCYQGFQAPQDGQGCVDVNECELLSGVCGEAFCENVEGSFLCVCADENQEYSPMT
                             ::::::::::::::::::::::::::::::::::::::
XP_005 ----------------------VNECELLSGVCGEAFCENVEGSFLCVCADENQEYSPMT
                                  1200      1210      1220         

         950       960       970       980       990      1000     
pF1KB3 GQCRSRTSTDLDVDVDQPKEEKKECYYNLNDASLCDNVLAPNVTKQECCCTSGAGWGDNC
       :::::::::::::::::::::::::::::::::::::::::::::::::::::.::::::
XP_005 GQCRSRTSTDLDVDVDQPKEEKKECYYNLNDASLCDNVLAPNVTKQECCCTSGVGWGDNC
    1230      1240      1250      1260      1270      1280         

        1010      1020      1030      1040      1050      1060     
pF1KB3 EIFPCPVLGTAEFTEMCPKGKGFVPAGESSSEAGGENYKDADECLLFGQEICKNGFCLNT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EIFPCPVLGTAEFTEMCPKGKGFVPAGESSSEAGGENYKDADECLLFGQEICKNGFCLNT
    1290      1300      1310      1320      1330      1340         

        1070      1080      1090      1100      1110      1120     
pF1KB3 RPGYECYCKQGTYYDPVKLQCFDMDECQDPSSCIDGQCVNTEGSYNCFCTHPMVLDASEK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RPGYECYCKQGTYYDPVKLQCFDMDECQDPSSCIDGQCVNTEGSYNCFCTHPMVLDASEK
    1350      1360      1370      1380      1390      1400         

        1130      1140      1150      1160      1170      1180     
pF1KB3 RCIRPAESNEQIEETDVYQDLCWEHLSDEYVCSRPLVGKQTTYTECCCLYGEAWGMQCAL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RCIRPAESNEQIEETDVYQDLCWEHLSDEYVCSRPLVGKQTTYTECCCLYGEAWGMQCAL
    1410      1420      1430      1440      1450      1460         

        1190      1200      1210      1220      1230      1240     
pF1KB3 CPLKDSDDYAQLCNIPVTGRRQPYGRDALVDFSEQYTPEADPYFIQDRFLNSFEELQAEE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 CPLKDSDDYAQLCNIPVTGRRQPYGRDALVDFSEQYTPEADPYFIQDRFLNSFEELQAEE
    1470      1480      1490      1500      1510      1520         

        1250      1260      1270      1280      1290      1300     
pF1KB3 CGILNGCENGRCVRVQEGYTCDCFDGYHLDTAKMTCVDVNECDELNNRMSLCKNAKCINT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 CGILNGCENGRCVRVQEGYTCDCFDGYHLDTAKMTCVDVNECDELNNRMSLCKNAKCINT
    1530      1540      1550      1560      1570      1580         

        1310      1320      1330      1340  
pF1KB3 DGSYKCLCLPGYVPSDKPNYCTPLNTALNLEKDSDLE
       :::::::::::::::::::::::::::::::::::::
XP_005 DGSYKCLCLPGYVPSDKPNYCTPLNTALNLEKDSDLE
    1590      1600      1610      1620      




1342 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Thu Nov  3 12:15:23 2016 done: Thu Nov  3 12:15:25 2016
 Total Scan time: 16.510 Total Display time:  0.670

Function used was FASTA [36.3.4 Apr, 2011]
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