Result of FASTA (omim) for pF1KA0901
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KA0901, 1215 aa
  1>>>pF1KA0901 1215 - 1215 aa - 1215 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 6.8455+/-0.000378; mu= 15.7840+/- 0.024
 mean_var=122.7142+/-25.379, 0's: 0 Z-trim(116.1): 168  B-trim: 1160 in 1/58
 Lambda= 0.115778
 statistics sampled from 26900 (27081) to 26900 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.674), E-opt: 0.2 (0.318), width:  16
 Scan time: 16.800

The best scores are:                                      opt bits E(85289)
NP_001308158 (OMIM: 300272,300863) histone deacety (1215) 8196 1381.2       0
NP_006035 (OMIM: 300272,300863) histone deacetylas (1215) 8196 1381.2       0
NP_001308156 (OMIM: 300272,300863) histone deacety (1215) 8196 1381.2       0
NP_001308157 (OMIM: 300272,300863) histone deacety (1215) 8196 1381.2       0
NP_001308155 (OMIM: 300272,300863) histone deacety (1215) 8196 1381.2       0
NP_001308154 (OMIM: 300272,300863) histone deacety (1229) 8196 1381.2       0
XP_016884676 (OMIM: 300272,300863) PREDICTED: hist ( 622) 4043 687.3  8e-197
NP_114408 (OMIM: 608544) histone deacetylase 10 is ( 669) 1378 242.2 8.4e-63
NP_001152758 (OMIM: 608544) histone deacetylase 10 ( 649)  997 178.6 1.2e-43
NP_001308159 (OMIM: 300272,300863) histone deacety ( 146)  952 170.6 6.6e-42
NP_001308160 (OMIM: 300272,300863) histone deacety ( 146)  952 170.6 6.6e-42
XP_011510532 (OMIM: 605314) PREDICTED: histone dea ( 673)  774 141.3   2e-32
XP_016860884 (OMIM: 605314) PREDICTED: histone dea ( 917)  774 141.4 2.5e-32
XP_011510529 (OMIM: 605314) PREDICTED: histone dea (1041)  774 141.5 2.8e-32
XP_006712942 (OMIM: 605314) PREDICTED: histone dea (1062)  774 141.5 2.9e-32
XP_006712943 (OMIM: 605314) PREDICTED: histone dea (1062)  774 141.5 2.9e-32
XP_011510528 (OMIM: 605314) PREDICTED: histone dea (1065)  774 141.5 2.9e-32
XP_016860883 (OMIM: 605314) PREDICTED: histone dea (1069)  774 141.5 2.9e-32
XP_011510527 (OMIM: 605314) PREDICTED: histone dea (1079)  774 141.5 2.9e-32
NP_006028 (OMIM: 605314) histone deacetylase 4 [Ho (1084)  774 141.5 2.9e-32
XP_011510526 (OMIM: 605314) PREDICTED: histone dea (1084)  774 141.5 2.9e-32
XP_011510524 (OMIM: 605314) PREDICTED: histone dea (1089)  774 141.5 2.9e-32
XP_011510523 (OMIM: 605314) PREDICTED: histone dea (1089)  774 141.5 2.9e-32
XP_011510525 (OMIM: 605314) PREDICTED: histone dea (1089)  774 141.5 2.9e-32
XP_006712941 (OMIM: 605314) PREDICTED: histone dea (1089)  774 141.5 2.9e-32
XP_011510522 (OMIM: 605314) PREDICTED: histone dea (1090)  774 141.5 2.9e-32
XP_011510521 (OMIM: 605314) PREDICTED: histone dea (1103)  774 141.5 2.9e-32
XP_011510520 (OMIM: 605314) PREDICTED: histone dea (1108)  774 141.5   3e-32
XP_006712940 (OMIM: 605314) PREDICTED: histone dea (1108)  774 141.5   3e-32
XP_011510519 (OMIM: 605314) PREDICTED: histone dea (1113)  774 141.5   3e-32
XP_011536784 (OMIM: 606542) PREDICTED: histone dea ( 952)  738 135.4 1.7e-30
XP_011536783 (OMIM: 606542) PREDICTED: histone dea ( 952)  738 135.4 1.7e-30
NP_001091886 (OMIM: 606542) histone deacetylase 7  ( 954)  738 135.4 1.7e-30
NP_001295019 (OMIM: 606542) histone deacetylase 7  ( 974)  738 135.4 1.7e-30
NP_056216 (OMIM: 606542) histone deacetylase 7 iso ( 991)  738 135.4 1.7e-30
XP_011536782 (OMIM: 606542) PREDICTED: histone dea ( 998)  738 135.4 1.8e-30
XP_011536781 (OMIM: 606542) PREDICTED: histone dea ( 998)  738 135.4 1.8e-30
XP_016874944 (OMIM: 606542) PREDICTED: histone dea (1018)  738 135.4 1.8e-30
XP_011536780 (OMIM: 606542) PREDICTED: histone dea (1035)  738 135.4 1.8e-30
XP_016879485 (OMIM: 605315) PREDICTED: histone dea (1081)  720 132.5 1.5e-29
XP_011522452 (OMIM: 605315) PREDICTED: histone dea (1113)  720 132.5 1.5e-29
XP_016879484 (OMIM: 605315) PREDICTED: histone dea (1113)  720 132.5 1.5e-29
XP_011522451 (OMIM: 605315) PREDICTED: histone dea (1114)  720 132.5 1.5e-29
XP_016879483 (OMIM: 605315) PREDICTED: histone dea (1120)  720 132.5 1.5e-29
XP_005256963 (OMIM: 605315) PREDICTED: histone dea (1122)  720 132.5 1.5e-29
XP_005256962 (OMIM: 605315) PREDICTED: histone dea (1122)  720 132.5 1.5e-29
NP_005465 (OMIM: 605315) histone deacetylase 5 iso (1122)  720 132.5 1.5e-29
NP_001015053 (OMIM: 605315) histone deacetylase 5  (1123)  720 132.5 1.5e-29
XP_016879482 (OMIM: 605315) PREDICTED: histone dea (1152)  720 132.5 1.6e-29
XP_016879481 (OMIM: 605315) PREDICTED: histone dea (1156)  720 132.5 1.6e-29


>>NP_001308158 (OMIM: 300272,300863) histone deacetylase  (1215 aa)
 initn: 8196 init1: 8196 opt: 8196  Z-score: 7399.5  bits: 1381.2 E(85289):    0
Smith-Waterman score: 8196; 100.0% identity (100.0% similar) in 1215 aa overlap (1-1215:1-1215)

               10        20        30        40        50        60
pF1KA0 MTSTGQDSTTTRQRRSRQNPQSPPQDSSVTSKRNIKKGAVPRSIPNLAEVKKKGKMKKLG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MTSTGQDSTTTRQRRSRQNPQSPPQDSSVTSKRNIKKGAVPRSIPNLAEVKKKGKMKKLG
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KA0 QAMEEDLIVGLQGMDLNLEAEALAGTGLVLDEQLNEFHCLWDDSFPEGPERLHAIKEQLI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QAMEEDLIVGLQGMDLNLEAEALAGTGLVLDEQLNEFHCLWDDSFPEGPERLHAIKEQLI
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KA0 QEGLLDRCVSFQARFAEKEELMLVHSLEYIDLMETTQYMNEGELRVLADTYDSVYLHPNS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QEGLLDRCVSFQARFAEKEELMLVHSLEYIDLMETTQYMNEGELRVLADTYDSVYLHPNS
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KA0 YSCACLASGSVLRLVDAVLGAEIRNGMAIIRPPGHHAQHSLMDGYCMFNHVAVAARYAQQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YSCACLASGSVLRLVDAVLGAEIRNGMAIIRPPGHHAQHSLMDGYCMFNHVAVAARYAQQ
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KA0 KHRIRRVLIVDWDVHHGQGTQFTFDQDPSVLYFSIHRYEQGRFWPHLKASNWSTTGFGQG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KHRIRRVLIVDWDVHHGQGTQFTFDQDPSVLYFSIHRYEQGRFWPHLKASNWSTTGFGQG
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KA0 QGYTINVPWNQVGMRDADYIAAFLHVLLPVALEFQPQLVLVAAGFDALQGDPKGEMAATP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QGYTINVPWNQVGMRDADYIAAFLHVLLPVALEFQPQLVLVAAGFDALQGDPKGEMAATP
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KA0 AGFAQLTHLLMGLAGGKLILSLEGGYNLRALAEGVSASLHTLLGDPCPMLESPGAPCRSA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AGFAQLTHLLMGLAGGKLILSLEGGYNLRALAEGVSASLHTLLGDPCPMLESPGAPCRSA
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KA0 QASVSCALEALEPFWEVLVRSTETVERDNMEEDNVEESEEEGPWEPPVLPILTWPVLQSR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QASVSCALEALEPFWEVLVRSTETVERDNMEEDNVEESEEEGPWEPPVLPILTWPVLQSR
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KA0 TGLVYDQNMMNHCNLWDSHHPEVPQRILRIMCRLEELGLAGRCLTLTPRPATEAELLTCH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TGLVYDQNMMNHCNLWDSHHPEVPQRILRIMCRLEELGLAGRCLTLTPRPATEAELLTCH
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KA0 SAEYVGHLRATEKMKTRELHRESSNFDSIYICPSTFACAQLATGAACRLVEAVLSGEVLN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SAEYVGHLRATEKMKTRELHRESSNFDSIYICPSTFACAQLATGAACRLVEAVLSGEVLN
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KA0 GAAVVRPPGHHAEQDAACGFCFFNSVAVAARHAQTISGHALRILIVDWDVHHGNGTQHMF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GAAVVRPPGHHAEQDAACGFCFFNSVAVAARHAQTISGHALRILIVDWDVHHGNGTQHMF
              610       620       630       640       650       660

              670       680       690       700       710       720
pF1KA0 EDDPSVLYVSLHRYDHGTFFPMGDEGASSQIGRAAGTGFTVNVAWNGPRMGDADYLAAWH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EDDPSVLYVSLHRYDHGTFFPMGDEGASSQIGRAAGTGFTVNVAWNGPRMGDADYLAAWH
              670       680       690       700       710       720

              730       740       750       760       770       780
pF1KA0 RLVLPIAYEFNPELVLVSAGFDAARGDPLGGCQVSPEGYAHLTHLLMGLASGRIILILEG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RLVLPIAYEFNPELVLVSAGFDAARGDPLGGCQVSPEGYAHLTHLLMGLASGRIILILEG
              730       740       750       760       770       780

              790       800       810       820       830       840
pF1KA0 GYNLTSISESMAACTRSLLGDPPPLLTLPRPPLSGALASITETIQVHRRYWRSLRVMKVE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GYNLTSISESMAACTRSLLGDPPPLLTLPRPPLSGALASITETIQVHRRYWRSLRVMKVE
              790       800       810       820       830       840

              850       860       870       880       890       900
pF1KA0 DREGPSSSKLVTKKAPQPAKPRLAERMTTREKKVLEAGMGKVTSASFGEESTPGQTNSET
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DREGPSSSKLVTKKAPQPAKPRLAERMTTREKKVLEAGMGKVTSASFGEESTPGQTNSET
              850       860       870       880       890       900

              910       920       930       940       950       960
pF1KA0 AVVALTQDQPSEAATGGATLAQTISEAAIGGAMLGQTTSEEAVGGATPDQTTSEETVGGA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AVVALTQDQPSEAATGGATLAQTISEAAIGGAMLGQTTSEEAVGGATPDQTTSEETVGGA
              910       920       930       940       950       960

              970       980       990      1000      1010      1020
pF1KA0 ILDQTTSEDAVGGATLGQTTSEEAVGGATLAQTTSEAAMEGATLDQTTSEEAPGGTELIQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ILDQTTSEDAVGGATLGQTTSEEAVGGATLAQTTSEAAMEGATLDQTTSEEAPGGTELIQ
              970       980       990      1000      1010      1020

             1030      1040      1050      1060      1070      1080
pF1KA0 TPLASSTDHQTPPTSPVQGTTPQISPSTLIGSLRTLELGSESQGASESQAPGEENLLGEA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TPLASSTDHQTPPTSPVQGTTPQISPSTLIGSLRTLELGSESQGASESQAPGEENLLGEA
             1030      1040      1050      1060      1070      1080

             1090      1100      1110      1120      1130      1140
pF1KA0 AGGQDMADSMLMQGSRGLTDQAIFYAVTPLPWCPHLVAVCPIPAAGLDVTQPCGDCGTIQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AGGQDMADSMLMQGSRGLTDQAIFYAVTPLPWCPHLVAVCPIPAAGLDVTQPCGDCGTIQ
             1090      1100      1110      1120      1130      1140

             1150      1160      1170      1180      1190      1200
pF1KA0 ENWVCLSCYQVYCGRYINGHMLQHHGNSGHPLVLSYIDLSAWCYYCQAYVHHQALLDVKN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ENWVCLSCYQVYCGRYINGHMLQHHGNSGHPLVLSYIDLSAWCYYCQAYVHHQALLDVKN
             1150      1160      1170      1180      1190      1200

             1210     
pF1KA0 IAHQNKFGEDMPHPH
       :::::::::::::::
NP_001 IAHQNKFGEDMPHPH
             1210     

>>NP_006035 (OMIM: 300272,300863) histone deacetylase 6   (1215 aa)
 initn: 8196 init1: 8196 opt: 8196  Z-score: 7399.5  bits: 1381.2 E(85289):    0
Smith-Waterman score: 8196; 100.0% identity (100.0% similar) in 1215 aa overlap (1-1215:1-1215)

               10        20        30        40        50        60
pF1KA0 MTSTGQDSTTTRQRRSRQNPQSPPQDSSVTSKRNIKKGAVPRSIPNLAEVKKKGKMKKLG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 MTSTGQDSTTTRQRRSRQNPQSPPQDSSVTSKRNIKKGAVPRSIPNLAEVKKKGKMKKLG
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KA0 QAMEEDLIVGLQGMDLNLEAEALAGTGLVLDEQLNEFHCLWDDSFPEGPERLHAIKEQLI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 QAMEEDLIVGLQGMDLNLEAEALAGTGLVLDEQLNEFHCLWDDSFPEGPERLHAIKEQLI
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KA0 QEGLLDRCVSFQARFAEKEELMLVHSLEYIDLMETTQYMNEGELRVLADTYDSVYLHPNS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 QEGLLDRCVSFQARFAEKEELMLVHSLEYIDLMETTQYMNEGELRVLADTYDSVYLHPNS
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KA0 YSCACLASGSVLRLVDAVLGAEIRNGMAIIRPPGHHAQHSLMDGYCMFNHVAVAARYAQQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 YSCACLASGSVLRLVDAVLGAEIRNGMAIIRPPGHHAQHSLMDGYCMFNHVAVAARYAQQ
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KA0 KHRIRRVLIVDWDVHHGQGTQFTFDQDPSVLYFSIHRYEQGRFWPHLKASNWSTTGFGQG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 KHRIRRVLIVDWDVHHGQGTQFTFDQDPSVLYFSIHRYEQGRFWPHLKASNWSTTGFGQG
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KA0 QGYTINVPWNQVGMRDADYIAAFLHVLLPVALEFQPQLVLVAAGFDALQGDPKGEMAATP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 QGYTINVPWNQVGMRDADYIAAFLHVLLPVALEFQPQLVLVAAGFDALQGDPKGEMAATP
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KA0 AGFAQLTHLLMGLAGGKLILSLEGGYNLRALAEGVSASLHTLLGDPCPMLESPGAPCRSA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 AGFAQLTHLLMGLAGGKLILSLEGGYNLRALAEGVSASLHTLLGDPCPMLESPGAPCRSA
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KA0 QASVSCALEALEPFWEVLVRSTETVERDNMEEDNVEESEEEGPWEPPVLPILTWPVLQSR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 QASVSCALEALEPFWEVLVRSTETVERDNMEEDNVEESEEEGPWEPPVLPILTWPVLQSR
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KA0 TGLVYDQNMMNHCNLWDSHHPEVPQRILRIMCRLEELGLAGRCLTLTPRPATEAELLTCH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 TGLVYDQNMMNHCNLWDSHHPEVPQRILRIMCRLEELGLAGRCLTLTPRPATEAELLTCH
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KA0 SAEYVGHLRATEKMKTRELHRESSNFDSIYICPSTFACAQLATGAACRLVEAVLSGEVLN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 SAEYVGHLRATEKMKTRELHRESSNFDSIYICPSTFACAQLATGAACRLVEAVLSGEVLN
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KA0 GAAVVRPPGHHAEQDAACGFCFFNSVAVAARHAQTISGHALRILIVDWDVHHGNGTQHMF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 GAAVVRPPGHHAEQDAACGFCFFNSVAVAARHAQTISGHALRILIVDWDVHHGNGTQHMF
              610       620       630       640       650       660

              670       680       690       700       710       720
pF1KA0 EDDPSVLYVSLHRYDHGTFFPMGDEGASSQIGRAAGTGFTVNVAWNGPRMGDADYLAAWH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 EDDPSVLYVSLHRYDHGTFFPMGDEGASSQIGRAAGTGFTVNVAWNGPRMGDADYLAAWH
              670       680       690       700       710       720

              730       740       750       760       770       780
pF1KA0 RLVLPIAYEFNPELVLVSAGFDAARGDPLGGCQVSPEGYAHLTHLLMGLASGRIILILEG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 RLVLPIAYEFNPELVLVSAGFDAARGDPLGGCQVSPEGYAHLTHLLMGLASGRIILILEG
              730       740       750       760       770       780

              790       800       810       820       830       840
pF1KA0 GYNLTSISESMAACTRSLLGDPPPLLTLPRPPLSGALASITETIQVHRRYWRSLRVMKVE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 GYNLTSISESMAACTRSLLGDPPPLLTLPRPPLSGALASITETIQVHRRYWRSLRVMKVE
              790       800       810       820       830       840

              850       860       870       880       890       900
pF1KA0 DREGPSSSKLVTKKAPQPAKPRLAERMTTREKKVLEAGMGKVTSASFGEESTPGQTNSET
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 DREGPSSSKLVTKKAPQPAKPRLAERMTTREKKVLEAGMGKVTSASFGEESTPGQTNSET
              850       860       870       880       890       900

              910       920       930       940       950       960
pF1KA0 AVVALTQDQPSEAATGGATLAQTISEAAIGGAMLGQTTSEEAVGGATPDQTTSEETVGGA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 AVVALTQDQPSEAATGGATLAQTISEAAIGGAMLGQTTSEEAVGGATPDQTTSEETVGGA
              910       920       930       940       950       960

              970       980       990      1000      1010      1020
pF1KA0 ILDQTTSEDAVGGATLGQTTSEEAVGGATLAQTTSEAAMEGATLDQTTSEEAPGGTELIQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 ILDQTTSEDAVGGATLGQTTSEEAVGGATLAQTTSEAAMEGATLDQTTSEEAPGGTELIQ
              970       980       990      1000      1010      1020

             1030      1040      1050      1060      1070      1080
pF1KA0 TPLASSTDHQTPPTSPVQGTTPQISPSTLIGSLRTLELGSESQGASESQAPGEENLLGEA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 TPLASSTDHQTPPTSPVQGTTPQISPSTLIGSLRTLELGSESQGASESQAPGEENLLGEA
             1030      1040      1050      1060      1070      1080

             1090      1100      1110      1120      1130      1140
pF1KA0 AGGQDMADSMLMQGSRGLTDQAIFYAVTPLPWCPHLVAVCPIPAAGLDVTQPCGDCGTIQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 AGGQDMADSMLMQGSRGLTDQAIFYAVTPLPWCPHLVAVCPIPAAGLDVTQPCGDCGTIQ
             1090      1100      1110      1120      1130      1140

             1150      1160      1170      1180      1190      1200
pF1KA0 ENWVCLSCYQVYCGRYINGHMLQHHGNSGHPLVLSYIDLSAWCYYCQAYVHHQALLDVKN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 ENWVCLSCYQVYCGRYINGHMLQHHGNSGHPLVLSYIDLSAWCYYCQAYVHHQALLDVKN
             1150      1160      1170      1180      1190      1200

             1210     
pF1KA0 IAHQNKFGEDMPHPH
       :::::::::::::::
NP_006 IAHQNKFGEDMPHPH
             1210     

>>NP_001308156 (OMIM: 300272,300863) histone deacetylase  (1215 aa)
 initn: 8196 init1: 8196 opt: 8196  Z-score: 7399.5  bits: 1381.2 E(85289):    0
Smith-Waterman score: 8196; 100.0% identity (100.0% similar) in 1215 aa overlap (1-1215:1-1215)

               10        20        30        40        50        60
pF1KA0 MTSTGQDSTTTRQRRSRQNPQSPPQDSSVTSKRNIKKGAVPRSIPNLAEVKKKGKMKKLG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MTSTGQDSTTTRQRRSRQNPQSPPQDSSVTSKRNIKKGAVPRSIPNLAEVKKKGKMKKLG
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KA0 QAMEEDLIVGLQGMDLNLEAEALAGTGLVLDEQLNEFHCLWDDSFPEGPERLHAIKEQLI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QAMEEDLIVGLQGMDLNLEAEALAGTGLVLDEQLNEFHCLWDDSFPEGPERLHAIKEQLI
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KA0 QEGLLDRCVSFQARFAEKEELMLVHSLEYIDLMETTQYMNEGELRVLADTYDSVYLHPNS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QEGLLDRCVSFQARFAEKEELMLVHSLEYIDLMETTQYMNEGELRVLADTYDSVYLHPNS
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KA0 YSCACLASGSVLRLVDAVLGAEIRNGMAIIRPPGHHAQHSLMDGYCMFNHVAVAARYAQQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YSCACLASGSVLRLVDAVLGAEIRNGMAIIRPPGHHAQHSLMDGYCMFNHVAVAARYAQQ
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KA0 KHRIRRVLIVDWDVHHGQGTQFTFDQDPSVLYFSIHRYEQGRFWPHLKASNWSTTGFGQG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KHRIRRVLIVDWDVHHGQGTQFTFDQDPSVLYFSIHRYEQGRFWPHLKASNWSTTGFGQG
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KA0 QGYTINVPWNQVGMRDADYIAAFLHVLLPVALEFQPQLVLVAAGFDALQGDPKGEMAATP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QGYTINVPWNQVGMRDADYIAAFLHVLLPVALEFQPQLVLVAAGFDALQGDPKGEMAATP
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KA0 AGFAQLTHLLMGLAGGKLILSLEGGYNLRALAEGVSASLHTLLGDPCPMLESPGAPCRSA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AGFAQLTHLLMGLAGGKLILSLEGGYNLRALAEGVSASLHTLLGDPCPMLESPGAPCRSA
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KA0 QASVSCALEALEPFWEVLVRSTETVERDNMEEDNVEESEEEGPWEPPVLPILTWPVLQSR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QASVSCALEALEPFWEVLVRSTETVERDNMEEDNVEESEEEGPWEPPVLPILTWPVLQSR
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KA0 TGLVYDQNMMNHCNLWDSHHPEVPQRILRIMCRLEELGLAGRCLTLTPRPATEAELLTCH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TGLVYDQNMMNHCNLWDSHHPEVPQRILRIMCRLEELGLAGRCLTLTPRPATEAELLTCH
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KA0 SAEYVGHLRATEKMKTRELHRESSNFDSIYICPSTFACAQLATGAACRLVEAVLSGEVLN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SAEYVGHLRATEKMKTRELHRESSNFDSIYICPSTFACAQLATGAACRLVEAVLSGEVLN
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KA0 GAAVVRPPGHHAEQDAACGFCFFNSVAVAARHAQTISGHALRILIVDWDVHHGNGTQHMF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GAAVVRPPGHHAEQDAACGFCFFNSVAVAARHAQTISGHALRILIVDWDVHHGNGTQHMF
              610       620       630       640       650       660

              670       680       690       700       710       720
pF1KA0 EDDPSVLYVSLHRYDHGTFFPMGDEGASSQIGRAAGTGFTVNVAWNGPRMGDADYLAAWH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EDDPSVLYVSLHRYDHGTFFPMGDEGASSQIGRAAGTGFTVNVAWNGPRMGDADYLAAWH
              670       680       690       700       710       720

              730       740       750       760       770       780
pF1KA0 RLVLPIAYEFNPELVLVSAGFDAARGDPLGGCQVSPEGYAHLTHLLMGLASGRIILILEG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RLVLPIAYEFNPELVLVSAGFDAARGDPLGGCQVSPEGYAHLTHLLMGLASGRIILILEG
              730       740       750       760       770       780

              790       800       810       820       830       840
pF1KA0 GYNLTSISESMAACTRSLLGDPPPLLTLPRPPLSGALASITETIQVHRRYWRSLRVMKVE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GYNLTSISESMAACTRSLLGDPPPLLTLPRPPLSGALASITETIQVHRRYWRSLRVMKVE
              790       800       810       820       830       840

              850       860       870       880       890       900
pF1KA0 DREGPSSSKLVTKKAPQPAKPRLAERMTTREKKVLEAGMGKVTSASFGEESTPGQTNSET
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DREGPSSSKLVTKKAPQPAKPRLAERMTTREKKVLEAGMGKVTSASFGEESTPGQTNSET
              850       860       870       880       890       900

              910       920       930       940       950       960
pF1KA0 AVVALTQDQPSEAATGGATLAQTISEAAIGGAMLGQTTSEEAVGGATPDQTTSEETVGGA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AVVALTQDQPSEAATGGATLAQTISEAAIGGAMLGQTTSEEAVGGATPDQTTSEETVGGA
              910       920       930       940       950       960

              970       980       990      1000      1010      1020
pF1KA0 ILDQTTSEDAVGGATLGQTTSEEAVGGATLAQTTSEAAMEGATLDQTTSEEAPGGTELIQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ILDQTTSEDAVGGATLGQTTSEEAVGGATLAQTTSEAAMEGATLDQTTSEEAPGGTELIQ
              970       980       990      1000      1010      1020

             1030      1040      1050      1060      1070      1080
pF1KA0 TPLASSTDHQTPPTSPVQGTTPQISPSTLIGSLRTLELGSESQGASESQAPGEENLLGEA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TPLASSTDHQTPPTSPVQGTTPQISPSTLIGSLRTLELGSESQGASESQAPGEENLLGEA
             1030      1040      1050      1060      1070      1080

             1090      1100      1110      1120      1130      1140
pF1KA0 AGGQDMADSMLMQGSRGLTDQAIFYAVTPLPWCPHLVAVCPIPAAGLDVTQPCGDCGTIQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AGGQDMADSMLMQGSRGLTDQAIFYAVTPLPWCPHLVAVCPIPAAGLDVTQPCGDCGTIQ
             1090      1100      1110      1120      1130      1140

             1150      1160      1170      1180      1190      1200
pF1KA0 ENWVCLSCYQVYCGRYINGHMLQHHGNSGHPLVLSYIDLSAWCYYCQAYVHHQALLDVKN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ENWVCLSCYQVYCGRYINGHMLQHHGNSGHPLVLSYIDLSAWCYYCQAYVHHQALLDVKN
             1150      1160      1170      1180      1190      1200

             1210     
pF1KA0 IAHQNKFGEDMPHPH
       :::::::::::::::
NP_001 IAHQNKFGEDMPHPH
             1210     

>>NP_001308157 (OMIM: 300272,300863) histone deacetylase  (1215 aa)
 initn: 8196 init1: 8196 opt: 8196  Z-score: 7399.5  bits: 1381.2 E(85289):    0
Smith-Waterman score: 8196; 100.0% identity (100.0% similar) in 1215 aa overlap (1-1215:1-1215)

               10        20        30        40        50        60
pF1KA0 MTSTGQDSTTTRQRRSRQNPQSPPQDSSVTSKRNIKKGAVPRSIPNLAEVKKKGKMKKLG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MTSTGQDSTTTRQRRSRQNPQSPPQDSSVTSKRNIKKGAVPRSIPNLAEVKKKGKMKKLG
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KA0 QAMEEDLIVGLQGMDLNLEAEALAGTGLVLDEQLNEFHCLWDDSFPEGPERLHAIKEQLI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QAMEEDLIVGLQGMDLNLEAEALAGTGLVLDEQLNEFHCLWDDSFPEGPERLHAIKEQLI
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KA0 QEGLLDRCVSFQARFAEKEELMLVHSLEYIDLMETTQYMNEGELRVLADTYDSVYLHPNS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QEGLLDRCVSFQARFAEKEELMLVHSLEYIDLMETTQYMNEGELRVLADTYDSVYLHPNS
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KA0 YSCACLASGSVLRLVDAVLGAEIRNGMAIIRPPGHHAQHSLMDGYCMFNHVAVAARYAQQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YSCACLASGSVLRLVDAVLGAEIRNGMAIIRPPGHHAQHSLMDGYCMFNHVAVAARYAQQ
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KA0 KHRIRRVLIVDWDVHHGQGTQFTFDQDPSVLYFSIHRYEQGRFWPHLKASNWSTTGFGQG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KHRIRRVLIVDWDVHHGQGTQFTFDQDPSVLYFSIHRYEQGRFWPHLKASNWSTTGFGQG
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KA0 QGYTINVPWNQVGMRDADYIAAFLHVLLPVALEFQPQLVLVAAGFDALQGDPKGEMAATP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QGYTINVPWNQVGMRDADYIAAFLHVLLPVALEFQPQLVLVAAGFDALQGDPKGEMAATP
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KA0 AGFAQLTHLLMGLAGGKLILSLEGGYNLRALAEGVSASLHTLLGDPCPMLESPGAPCRSA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AGFAQLTHLLMGLAGGKLILSLEGGYNLRALAEGVSASLHTLLGDPCPMLESPGAPCRSA
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KA0 QASVSCALEALEPFWEVLVRSTETVERDNMEEDNVEESEEEGPWEPPVLPILTWPVLQSR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QASVSCALEALEPFWEVLVRSTETVERDNMEEDNVEESEEEGPWEPPVLPILTWPVLQSR
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KA0 TGLVYDQNMMNHCNLWDSHHPEVPQRILRIMCRLEELGLAGRCLTLTPRPATEAELLTCH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TGLVYDQNMMNHCNLWDSHHPEVPQRILRIMCRLEELGLAGRCLTLTPRPATEAELLTCH
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KA0 SAEYVGHLRATEKMKTRELHRESSNFDSIYICPSTFACAQLATGAACRLVEAVLSGEVLN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SAEYVGHLRATEKMKTRELHRESSNFDSIYICPSTFACAQLATGAACRLVEAVLSGEVLN
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KA0 GAAVVRPPGHHAEQDAACGFCFFNSVAVAARHAQTISGHALRILIVDWDVHHGNGTQHMF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GAAVVRPPGHHAEQDAACGFCFFNSVAVAARHAQTISGHALRILIVDWDVHHGNGTQHMF
              610       620       630       640       650       660

              670       680       690       700       710       720
pF1KA0 EDDPSVLYVSLHRYDHGTFFPMGDEGASSQIGRAAGTGFTVNVAWNGPRMGDADYLAAWH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EDDPSVLYVSLHRYDHGTFFPMGDEGASSQIGRAAGTGFTVNVAWNGPRMGDADYLAAWH
              670       680       690       700       710       720

              730       740       750       760       770       780
pF1KA0 RLVLPIAYEFNPELVLVSAGFDAARGDPLGGCQVSPEGYAHLTHLLMGLASGRIILILEG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RLVLPIAYEFNPELVLVSAGFDAARGDPLGGCQVSPEGYAHLTHLLMGLASGRIILILEG
              730       740       750       760       770       780

              790       800       810       820       830       840
pF1KA0 GYNLTSISESMAACTRSLLGDPPPLLTLPRPPLSGALASITETIQVHRRYWRSLRVMKVE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GYNLTSISESMAACTRSLLGDPPPLLTLPRPPLSGALASITETIQVHRRYWRSLRVMKVE
              790       800       810       820       830       840

              850       860       870       880       890       900
pF1KA0 DREGPSSSKLVTKKAPQPAKPRLAERMTTREKKVLEAGMGKVTSASFGEESTPGQTNSET
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DREGPSSSKLVTKKAPQPAKPRLAERMTTREKKVLEAGMGKVTSASFGEESTPGQTNSET
              850       860       870       880       890       900

              910       920       930       940       950       960
pF1KA0 AVVALTQDQPSEAATGGATLAQTISEAAIGGAMLGQTTSEEAVGGATPDQTTSEETVGGA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AVVALTQDQPSEAATGGATLAQTISEAAIGGAMLGQTTSEEAVGGATPDQTTSEETVGGA
              910       920       930       940       950       960

              970       980       990      1000      1010      1020
pF1KA0 ILDQTTSEDAVGGATLGQTTSEEAVGGATLAQTTSEAAMEGATLDQTTSEEAPGGTELIQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ILDQTTSEDAVGGATLGQTTSEEAVGGATLAQTTSEAAMEGATLDQTTSEEAPGGTELIQ
              970       980       990      1000      1010      1020

             1030      1040      1050      1060      1070      1080
pF1KA0 TPLASSTDHQTPPTSPVQGTTPQISPSTLIGSLRTLELGSESQGASESQAPGEENLLGEA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TPLASSTDHQTPPTSPVQGTTPQISPSTLIGSLRTLELGSESQGASESQAPGEENLLGEA
             1030      1040      1050      1060      1070      1080

             1090      1100      1110      1120      1130      1140
pF1KA0 AGGQDMADSMLMQGSRGLTDQAIFYAVTPLPWCPHLVAVCPIPAAGLDVTQPCGDCGTIQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AGGQDMADSMLMQGSRGLTDQAIFYAVTPLPWCPHLVAVCPIPAAGLDVTQPCGDCGTIQ
             1090      1100      1110      1120      1130      1140

             1150      1160      1170      1180      1190      1200
pF1KA0 ENWVCLSCYQVYCGRYINGHMLQHHGNSGHPLVLSYIDLSAWCYYCQAYVHHQALLDVKN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ENWVCLSCYQVYCGRYINGHMLQHHGNSGHPLVLSYIDLSAWCYYCQAYVHHQALLDVKN
             1150      1160      1170      1180      1190      1200

             1210     
pF1KA0 IAHQNKFGEDMPHPH
       :::::::::::::::
NP_001 IAHQNKFGEDMPHPH
             1210     

>>NP_001308155 (OMIM: 300272,300863) histone deacetylase  (1215 aa)
 initn: 8196 init1: 8196 opt: 8196  Z-score: 7399.5  bits: 1381.2 E(85289):    0
Smith-Waterman score: 8196; 100.0% identity (100.0% similar) in 1215 aa overlap (1-1215:1-1215)

               10        20        30        40        50        60
pF1KA0 MTSTGQDSTTTRQRRSRQNPQSPPQDSSVTSKRNIKKGAVPRSIPNLAEVKKKGKMKKLG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MTSTGQDSTTTRQRRSRQNPQSPPQDSSVTSKRNIKKGAVPRSIPNLAEVKKKGKMKKLG
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KA0 QAMEEDLIVGLQGMDLNLEAEALAGTGLVLDEQLNEFHCLWDDSFPEGPERLHAIKEQLI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QAMEEDLIVGLQGMDLNLEAEALAGTGLVLDEQLNEFHCLWDDSFPEGPERLHAIKEQLI
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KA0 QEGLLDRCVSFQARFAEKEELMLVHSLEYIDLMETTQYMNEGELRVLADTYDSVYLHPNS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QEGLLDRCVSFQARFAEKEELMLVHSLEYIDLMETTQYMNEGELRVLADTYDSVYLHPNS
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KA0 YSCACLASGSVLRLVDAVLGAEIRNGMAIIRPPGHHAQHSLMDGYCMFNHVAVAARYAQQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YSCACLASGSVLRLVDAVLGAEIRNGMAIIRPPGHHAQHSLMDGYCMFNHVAVAARYAQQ
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KA0 KHRIRRVLIVDWDVHHGQGTQFTFDQDPSVLYFSIHRYEQGRFWPHLKASNWSTTGFGQG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KHRIRRVLIVDWDVHHGQGTQFTFDQDPSVLYFSIHRYEQGRFWPHLKASNWSTTGFGQG
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KA0 QGYTINVPWNQVGMRDADYIAAFLHVLLPVALEFQPQLVLVAAGFDALQGDPKGEMAATP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QGYTINVPWNQVGMRDADYIAAFLHVLLPVALEFQPQLVLVAAGFDALQGDPKGEMAATP
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KA0 AGFAQLTHLLMGLAGGKLILSLEGGYNLRALAEGVSASLHTLLGDPCPMLESPGAPCRSA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AGFAQLTHLLMGLAGGKLILSLEGGYNLRALAEGVSASLHTLLGDPCPMLESPGAPCRSA
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KA0 QASVSCALEALEPFWEVLVRSTETVERDNMEEDNVEESEEEGPWEPPVLPILTWPVLQSR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QASVSCALEALEPFWEVLVRSTETVERDNMEEDNVEESEEEGPWEPPVLPILTWPVLQSR
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KA0 TGLVYDQNMMNHCNLWDSHHPEVPQRILRIMCRLEELGLAGRCLTLTPRPATEAELLTCH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TGLVYDQNMMNHCNLWDSHHPEVPQRILRIMCRLEELGLAGRCLTLTPRPATEAELLTCH
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KA0 SAEYVGHLRATEKMKTRELHRESSNFDSIYICPSTFACAQLATGAACRLVEAVLSGEVLN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SAEYVGHLRATEKMKTRELHRESSNFDSIYICPSTFACAQLATGAACRLVEAVLSGEVLN
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KA0 GAAVVRPPGHHAEQDAACGFCFFNSVAVAARHAQTISGHALRILIVDWDVHHGNGTQHMF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GAAVVRPPGHHAEQDAACGFCFFNSVAVAARHAQTISGHALRILIVDWDVHHGNGTQHMF
              610       620       630       640       650       660

              670       680       690       700       710       720
pF1KA0 EDDPSVLYVSLHRYDHGTFFPMGDEGASSQIGRAAGTGFTVNVAWNGPRMGDADYLAAWH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EDDPSVLYVSLHRYDHGTFFPMGDEGASSQIGRAAGTGFTVNVAWNGPRMGDADYLAAWH
              670       680       690       700       710       720

              730       740       750       760       770       780
pF1KA0 RLVLPIAYEFNPELVLVSAGFDAARGDPLGGCQVSPEGYAHLTHLLMGLASGRIILILEG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RLVLPIAYEFNPELVLVSAGFDAARGDPLGGCQVSPEGYAHLTHLLMGLASGRIILILEG
              730       740       750       760       770       780

              790       800       810       820       830       840
pF1KA0 GYNLTSISESMAACTRSLLGDPPPLLTLPRPPLSGALASITETIQVHRRYWRSLRVMKVE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GYNLTSISESMAACTRSLLGDPPPLLTLPRPPLSGALASITETIQVHRRYWRSLRVMKVE
              790       800       810       820       830       840

              850       860       870       880       890       900
pF1KA0 DREGPSSSKLVTKKAPQPAKPRLAERMTTREKKVLEAGMGKVTSASFGEESTPGQTNSET
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DREGPSSSKLVTKKAPQPAKPRLAERMTTREKKVLEAGMGKVTSASFGEESTPGQTNSET
              850       860       870       880       890       900

              910       920       930       940       950       960
pF1KA0 AVVALTQDQPSEAATGGATLAQTISEAAIGGAMLGQTTSEEAVGGATPDQTTSEETVGGA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AVVALTQDQPSEAATGGATLAQTISEAAIGGAMLGQTTSEEAVGGATPDQTTSEETVGGA
              910       920       930       940       950       960

              970       980       990      1000      1010      1020
pF1KA0 ILDQTTSEDAVGGATLGQTTSEEAVGGATLAQTTSEAAMEGATLDQTTSEEAPGGTELIQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ILDQTTSEDAVGGATLGQTTSEEAVGGATLAQTTSEAAMEGATLDQTTSEEAPGGTELIQ
              970       980       990      1000      1010      1020

             1030      1040      1050      1060      1070      1080
pF1KA0 TPLASSTDHQTPPTSPVQGTTPQISPSTLIGSLRTLELGSESQGASESQAPGEENLLGEA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TPLASSTDHQTPPTSPVQGTTPQISPSTLIGSLRTLELGSESQGASESQAPGEENLLGEA
             1030      1040      1050      1060      1070      1080

             1090      1100      1110      1120      1130      1140
pF1KA0 AGGQDMADSMLMQGSRGLTDQAIFYAVTPLPWCPHLVAVCPIPAAGLDVTQPCGDCGTIQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AGGQDMADSMLMQGSRGLTDQAIFYAVTPLPWCPHLVAVCPIPAAGLDVTQPCGDCGTIQ
             1090      1100      1110      1120      1130      1140

             1150      1160      1170      1180      1190      1200
pF1KA0 ENWVCLSCYQVYCGRYINGHMLQHHGNSGHPLVLSYIDLSAWCYYCQAYVHHQALLDVKN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ENWVCLSCYQVYCGRYINGHMLQHHGNSGHPLVLSYIDLSAWCYYCQAYVHHQALLDVKN
             1150      1160      1170      1180      1190      1200

             1210     
pF1KA0 IAHQNKFGEDMPHPH
       :::::::::::::::
NP_001 IAHQNKFGEDMPHPH
             1210     

>>NP_001308154 (OMIM: 300272,300863) histone deacetylase  (1229 aa)
 initn: 8196 init1: 8196 opt: 8196  Z-score: 7399.4  bits: 1381.2 E(85289):    0
Smith-Waterman score: 8196; 100.0% identity (100.0% similar) in 1215 aa overlap (1-1215:15-1229)

                             10        20        30        40      
pF1KA0               MTSTGQDSTTTRQRRSRQNPQSPPQDSSVTSKRNIKKGAVPRSIPN
                     ::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MSGANRGRGQASSTMTSTGQDSTTTRQRRSRQNPQSPPQDSSVTSKRNIKKGAVPRSIPN
               10        20        30        40        50        60

         50        60        70        80        90       100      
pF1KA0 LAEVKKKGKMKKLGQAMEEDLIVGLQGMDLNLEAEALAGTGLVLDEQLNEFHCLWDDSFP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LAEVKKKGKMKKLGQAMEEDLIVGLQGMDLNLEAEALAGTGLVLDEQLNEFHCLWDDSFP
               70        80        90       100       110       120

        110       120       130       140       150       160      
pF1KA0 EGPERLHAIKEQLIQEGLLDRCVSFQARFAEKEELMLVHSLEYIDLMETTQYMNEGELRV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EGPERLHAIKEQLIQEGLLDRCVSFQARFAEKEELMLVHSLEYIDLMETTQYMNEGELRV
              130       140       150       160       170       180

        170       180       190       200       210       220      
pF1KA0 LADTYDSVYLHPNSYSCACLASGSVLRLVDAVLGAEIRNGMAIIRPPGHHAQHSLMDGYC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LADTYDSVYLHPNSYSCACLASGSVLRLVDAVLGAEIRNGMAIIRPPGHHAQHSLMDGYC
              190       200       210       220       230       240

        230       240       250       260       270       280      
pF1KA0 MFNHVAVAARYAQQKHRIRRVLIVDWDVHHGQGTQFTFDQDPSVLYFSIHRYEQGRFWPH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MFNHVAVAARYAQQKHRIRRVLIVDWDVHHGQGTQFTFDQDPSVLYFSIHRYEQGRFWPH
              250       260       270       280       290       300

        290       300       310       320       330       340      
pF1KA0 LKASNWSTTGFGQGQGYTINVPWNQVGMRDADYIAAFLHVLLPVALEFQPQLVLVAAGFD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LKASNWSTTGFGQGQGYTINVPWNQVGMRDADYIAAFLHVLLPVALEFQPQLVLVAAGFD
              310       320       330       340       350       360

        350       360       370       380       390       400      
pF1KA0 ALQGDPKGEMAATPAGFAQLTHLLMGLAGGKLILSLEGGYNLRALAEGVSASLHTLLGDP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ALQGDPKGEMAATPAGFAQLTHLLMGLAGGKLILSLEGGYNLRALAEGVSASLHTLLGDP
              370       380       390       400       410       420

        410       420       430       440       450       460      
pF1KA0 CPMLESPGAPCRSAQASVSCALEALEPFWEVLVRSTETVERDNMEEDNVEESEEEGPWEP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CPMLESPGAPCRSAQASVSCALEALEPFWEVLVRSTETVERDNMEEDNVEESEEEGPWEP
              430       440       450       460       470       480

        470       480       490       500       510       520      
pF1KA0 PVLPILTWPVLQSRTGLVYDQNMMNHCNLWDSHHPEVPQRILRIMCRLEELGLAGRCLTL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PVLPILTWPVLQSRTGLVYDQNMMNHCNLWDSHHPEVPQRILRIMCRLEELGLAGRCLTL
              490       500       510       520       530       540

        530       540       550       560       570       580      
pF1KA0 TPRPATEAELLTCHSAEYVGHLRATEKMKTRELHRESSNFDSIYICPSTFACAQLATGAA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TPRPATEAELLTCHSAEYVGHLRATEKMKTRELHRESSNFDSIYICPSTFACAQLATGAA
              550       560       570       580       590       600

        590       600       610       620       630       640      
pF1KA0 CRLVEAVLSGEVLNGAAVVRPPGHHAEQDAACGFCFFNSVAVAARHAQTISGHALRILIV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CRLVEAVLSGEVLNGAAVVRPPGHHAEQDAACGFCFFNSVAVAARHAQTISGHALRILIV
              610       620       630       640       650       660

        650       660       670       680       690       700      
pF1KA0 DWDVHHGNGTQHMFEDDPSVLYVSLHRYDHGTFFPMGDEGASSQIGRAAGTGFTVNVAWN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DWDVHHGNGTQHMFEDDPSVLYVSLHRYDHGTFFPMGDEGASSQIGRAAGTGFTVNVAWN
              670       680       690       700       710       720

        710       720       730       740       750       760      
pF1KA0 GPRMGDADYLAAWHRLVLPIAYEFNPELVLVSAGFDAARGDPLGGCQVSPEGYAHLTHLL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GPRMGDADYLAAWHRLVLPIAYEFNPELVLVSAGFDAARGDPLGGCQVSPEGYAHLTHLL
              730       740       750       760       770       780

        770       780       790       800       810       820      
pF1KA0 MGLASGRIILILEGGYNLTSISESMAACTRSLLGDPPPLLTLPRPPLSGALASITETIQV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MGLASGRIILILEGGYNLTSISESMAACTRSLLGDPPPLLTLPRPPLSGALASITETIQV
              790       800       810       820       830       840

        830       840       850       860       870       880      
pF1KA0 HRRYWRSLRVMKVEDREGPSSSKLVTKKAPQPAKPRLAERMTTREKKVLEAGMGKVTSAS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HRRYWRSLRVMKVEDREGPSSSKLVTKKAPQPAKPRLAERMTTREKKVLEAGMGKVTSAS
              850       860       870       880       890       900

        890       900       910       920       930       940      
pF1KA0 FGEESTPGQTNSETAVVALTQDQPSEAATGGATLAQTISEAAIGGAMLGQTTSEEAVGGA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FGEESTPGQTNSETAVVALTQDQPSEAATGGATLAQTISEAAIGGAMLGQTTSEEAVGGA
              910       920       930       940       950       960

        950       960       970       980       990      1000      
pF1KA0 TPDQTTSEETVGGAILDQTTSEDAVGGATLGQTTSEEAVGGATLAQTTSEAAMEGATLDQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TPDQTTSEETVGGAILDQTTSEDAVGGATLGQTTSEEAVGGATLAQTTSEAAMEGATLDQ
              970       980       990      1000      1010      1020

       1010      1020      1030      1040      1050      1060      
pF1KA0 TTSEEAPGGTELIQTPLASSTDHQTPPTSPVQGTTPQISPSTLIGSLRTLELGSESQGAS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TTSEEAPGGTELIQTPLASSTDHQTPPTSPVQGTTPQISPSTLIGSLRTLELGSESQGAS
             1030      1040      1050      1060      1070      1080

       1070      1080      1090      1100      1110      1120      
pF1KA0 ESQAPGEENLLGEAAGGQDMADSMLMQGSRGLTDQAIFYAVTPLPWCPHLVAVCPIPAAG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ESQAPGEENLLGEAAGGQDMADSMLMQGSRGLTDQAIFYAVTPLPWCPHLVAVCPIPAAG
             1090      1100      1110      1120      1130      1140

       1130      1140      1150      1160      1170      1180      
pF1KA0 LDVTQPCGDCGTIQENWVCLSCYQVYCGRYINGHMLQHHGNSGHPLVLSYIDLSAWCYYC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LDVTQPCGDCGTIQENWVCLSCYQVYCGRYINGHMLQHHGNSGHPLVLSYIDLSAWCYYC
             1150      1160      1170      1180      1190      1200

       1190      1200      1210     
pF1KA0 QAYVHHQALLDVKNIAHQNKFGEDMPHPH
       :::::::::::::::::::::::::::::
NP_001 QAYVHHQALLDVKNIAHQNKFGEDMPHPH
             1210      1220         

>>XP_016884676 (OMIM: 300272,300863) PREDICTED: histone   (622 aa)
 initn: 4043 init1: 4043 opt: 4043  Z-score: 3654.6  bits: 687.3 E(85289): 8e-197
Smith-Waterman score: 4043; 100.0% identity (100.0% similar) in 597 aa overlap (1-597:15-611)

                             10        20        30        40      
pF1KA0               MTSTGQDSTTTRQRRSRQNPQSPPQDSSVTSKRNIKKGAVPRSIPN
                     ::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MSGANRGRGQASSTMTSTGQDSTTTRQRRSRQNPQSPPQDSSVTSKRNIKKGAVPRSIPN
               10        20        30        40        50        60

         50        60        70        80        90       100      
pF1KA0 LAEVKKKGKMKKLGQAMEEDLIVGLQGMDLNLEAEALAGTGLVLDEQLNEFHCLWDDSFP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LAEVKKKGKMKKLGQAMEEDLIVGLQGMDLNLEAEALAGTGLVLDEQLNEFHCLWDDSFP
               70        80        90       100       110       120

        110       120       130       140       150       160      
pF1KA0 EGPERLHAIKEQLIQEGLLDRCVSFQARFAEKEELMLVHSLEYIDLMETTQYMNEGELRV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EGPERLHAIKEQLIQEGLLDRCVSFQARFAEKEELMLVHSLEYIDLMETTQYMNEGELRV
              130       140       150       160       170       180

        170       180       190       200       210       220      
pF1KA0 LADTYDSVYLHPNSYSCACLASGSVLRLVDAVLGAEIRNGMAIIRPPGHHAQHSLMDGYC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LADTYDSVYLHPNSYSCACLASGSVLRLVDAVLGAEIRNGMAIIRPPGHHAQHSLMDGYC
              190       200       210       220       230       240

        230       240       250       260       270       280      
pF1KA0 MFNHVAVAARYAQQKHRIRRVLIVDWDVHHGQGTQFTFDQDPSVLYFSIHRYEQGRFWPH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MFNHVAVAARYAQQKHRIRRVLIVDWDVHHGQGTQFTFDQDPSVLYFSIHRYEQGRFWPH
              250       260       270       280       290       300

        290       300       310       320       330       340      
pF1KA0 LKASNWSTTGFGQGQGYTINVPWNQVGMRDADYIAAFLHVLLPVALEFQPQLVLVAAGFD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LKASNWSTTGFGQGQGYTINVPWNQVGMRDADYIAAFLHVLLPVALEFQPQLVLVAAGFD
              310       320       330       340       350       360

        350       360       370       380       390       400      
pF1KA0 ALQGDPKGEMAATPAGFAQLTHLLMGLAGGKLILSLEGGYNLRALAEGVSASLHTLLGDP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ALQGDPKGEMAATPAGFAQLTHLLMGLAGGKLILSLEGGYNLRALAEGVSASLHTLLGDP
              370       380       390       400       410       420

        410       420       430       440       450       460      
pF1KA0 CPMLESPGAPCRSAQASVSCALEALEPFWEVLVRSTETVERDNMEEDNVEESEEEGPWEP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CPMLESPGAPCRSAQASVSCALEALEPFWEVLVRSTETVERDNMEEDNVEESEEEGPWEP
              430       440       450       460       470       480

        470       480       490       500       510       520      
pF1KA0 PVLPILTWPVLQSRTGLVYDQNMMNHCNLWDSHHPEVPQRILRIMCRLEELGLAGRCLTL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PVLPILTWPVLQSRTGLVYDQNMMNHCNLWDSHHPEVPQRILRIMCRLEELGLAGRCLTL
              490       500       510       520       530       540

        530       540       550       560       570       580      
pF1KA0 TPRPATEAELLTCHSAEYVGHLRATEKMKTRELHRESSNFDSIYICPSTFACAQLATGAA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TPRPATEAELLTCHSAEYVGHLRATEKMKTRELHRESSNFDSIYICPSTFACAQLATGAA
              550       560       570       580       590       600

        590       600       610       620       630       640      
pF1KA0 CRLVEAVLSGEVLNGAAVVRPPGHHAEQDAACGFCFFNSVAVAARHAQTISGHALRILIV
       :::::::::::                                                 
XP_016 CRLVEAVLSGEDPDCGLGCPPR                                      
              610       620                                        

>>NP_114408 (OMIM: 608544) histone deacetylase 10 isofor  (669 aa)
 initn: 1492 init1: 1328 opt: 1378  Z-score: 1248.4  bits: 242.2 E(85289): 8.4e-63
Smith-Waterman score: 1414; 39.4% identity (62.6% similar) in 728 aa overlap (85-806:2-633)

           60        70        80        90       100         110  
pF1KA0 KMKKLGQAMEEDLIVGLQGMDLNLEAEALAGTGLVLDEQLNEFHCLWDDSF--PEGPERL
                                     ::.::  :...  . ::::     : ::::
NP_114                              MGTALVYHEDMTATRLLWDDPECEIERPERL
                                            10        20        30 

            120       130       140       150       160       170  
pF1KA0 HAIKEQLIQEGLLDRCVSFQARFAEKEELMLVHSLEYIDLMETTQYMNEGELRVLADTYD
        :  ..: :.:: .::. ..:: : .::: :::: ::..:.. :: ... ::..:.  .:
NP_114 TAALDRLRQRGLEQRCLRLSAREASEEELGLVHSPEYVSLVRETQVLGKEELQALSGQFD
              40        50        60        70        80        90 

            180       190       200       210       220       230  
pF1KA0 SVYLHPNSYSCACLASGSVLRLVDAVLGAEIRNGMAIIRPPGHHAQHSLMDGYCMFNHVA
       ..:.::... :: ::.:. :.:::::: . ..::.:..::::::.:..  .:.:.::.::
NP_114 AIYFHPSTFHCARLAAGAGLQLVDAVLTGAVQNGLALVRPPGHHGQRAAANGFCVFNNVA
             100       110       120       130       140       150 

            240       250       260       270       280       290  
pF1KA0 VAARYAQQKHRIRRVLIVDWDVHHGQGTQFTFDQDPSVLYFSIHRYEQGRFWPHLKASNW
       .:: .:.::: ..:.:.:::::::::: :. :..:::::::: ::::.::::: :. :. 
NP_114 IAAAHAKQKHGLHRILVVDWDVHHGQGIQYLFEDDPSVLYFSWHRYEHGRFWPFLRESDA
             160       170       180       190       200       210 

            300       310       320       330       340       350  
pF1KA0 STTGFGQGQGYTINVPWNQVGMRDADYIAAFLHVLLPVALEFQPQLVLVAAGFDALQGDP
       ...: ::: :.:.:.::::::: .:::.:::::.:::.:.::.:.::::.::::.  :::
NP_114 DAVGRGQGLGFTVNLPWNQVGMGNADYVAAFLHLLLPLAFEFDPELVLVSAGFDSAIGDP
             220       230       240       250       260       270 

            360       370       380       390       400       410  
pF1KA0 KGEMAATPAGFAQLTHLLMGLAGGKLILSLEGGYNLRALAEGVSASLHTLLGDPCPMLES
       .:.: :::  ::.::.::. ::::..   :::::.:..:::.:  ...:::::: : : .
NP_114 EGQMQATPECFAHLTQLLQVLAGGRVCAVLEGGYHLESLAESVCMTVQTLLGDPAPPLSG
             280       290       300       310       320       330 

            420       430       440       450       460       470  
pF1KA0 PGAPCRSAQASVSCALEALEPFWEVLVRSTETVERDNMEEDNVEESEEEGPWEPPVLPIL
       : :::.::  :.. :  :  : :. : ..  :.    .  .   .: :  :  ::.::  
NP_114 PMAPCQSALESIQSARAAQAPHWKSLQQQDVTA----VPMSPSSHSPEGRP--PPLLP--
             340       350       360           370         380     

               480       490       500       510       520         
pF1KA0 TWPVLQ---SRTGLVYDQNMMNHCNLWDSHHPEVPQRILRIMCRLEELGLAGRCLTLTPR
         :: .   :  . . ::  .  :          :   .:    :    ..   :.: : 
NP_114 GGPVCKAAASAPSSLLDQPCL--C----------PAPSVRTAVALTTPDIT---LVLPPD
           390       400                   410       420           

     530        540       550       560       570       580        
pF1KA0 PAT-EAELLTCHSAEYVGHLRATEKMKTRELHRESSNFDSIYICPSTFACAQLATGAACR
           ::  :  ..  ..   :  :..  .:                    :  : :    
NP_114 VIQQEASALREETEAWA---RPHESLAREE--------------------ALTALGKLLY
      430       440          450                           460     

      590       600       610       620       630       640        
pF1KA0 LVEAVLSGEVLNGAAVVRPPGHHAEQDAACGFCFFNSVAVAARHAQTISGHALRILIVDW
       :....:.:.: .: :..  :.  :   ::       .. ::.:..  .:  : :.: :  
NP_114 LLDGMLDGQVNSGIAAT--PASAA---AA-------TLDVAVRRG--LSHGAQRLLCVA-
         470       480                   490         500       510 

      650       660       670       680       690       700        
pF1KA0 DVHHGNGTQHMFEDDPSVLYVSLHRYDHGTFFPMGDEGASSQIGRAAGTGFTVNVAWNGP
        . . .    . .:  : :.....          : :.:. ..       : :..    :
NP_114 -LGQLDRPPDLAHDGRS-LWLNIR----------GKEAAALSM-------FHVSTPL--P
               520        530                 540                  

      710       720       730       740       750       760        
pF1KA0 RMGDADYLAAWHRLVLPIAYEFNPELVLVSAGFDAARGDPLGGCQVSPEGYAHLTHLLMG
        :  . .:.    ::::.:: :.:.::::. :       :  : : .:.. : :. .: :
NP_114 VM-TGGFLSCILGLVLPLAYGFQPDLVLVALG-------PGHGLQ-GPHA-ALLAAMLRG
     550        560       570       580               590          

      770       780       790       800       810       820        
pF1KA0 LASGRIILILEGGYNLTSISESMAACTRSLLGDPPPLLTLPRPPLSGALASITETIQVHR
       ::.::.. .::     .:  .  .  .: : :. :: :                      
NP_114 LAGGRVLALLE----ENSTPQLAGILARVLNGEAPPSLGPSSVASPEDVQALMYLRGQLE
     600       610           620       630       640       650     

      830       840       850       860       870       880        
pF1KA0 RYWRSLRVMKVEDREGPSSSKLVTKKAPQPAKPRLAERMTTREKKVLEAGMGKVTSASFG
                                                                   
NP_114 PQWKMLQCHPHLVA                                              
         660                                                       

>>NP_001152758 (OMIM: 608544) histone deacetylase 10 iso  (649 aa)
 initn: 1096 init1: 957 opt: 997  Z-score: 904.7  bits: 178.6 E(85289): 1.2e-43
Smith-Waterman score: 1271; 37.6% identity (60.2% similar) in 728 aa overlap (85-806:2-613)

           60        70        80        90       100         110  
pF1KA0 KMKKLGQAMEEDLIVGLQGMDLNLEAEALAGTGLVLDEQLNEFHCLWDDSF--PEGPERL
                                     ::.::  :...  . ::::     : ::::
NP_001                              MGTALVYHEDMTATRLLWDDPECEIERPERL
                                            10        20        30 

            120       130       140       150       160       170  
pF1KA0 HAIKEQLIQEGLLDRCVSFQARFAEKEELMLVHSLEYIDLMETTQYMNEGELRVLADTYD
        :  ..: :.:: .::. ..:: : .::: :::: ::..:.. :: ... ::..:.  .:
NP_001 TAALDRLRQRGLEQRCLRLSAREASEEELGLVHSPEYVSLVRETQVLGKEELQALSGQFD
              40        50        60        70        80        90 

            180       190       200       210       220       230  
pF1KA0 SVYLHPNSYSCACLASGSVLRLVDAVLGAEIRNGMAIIRPPGHHAQHSLMDGYCMFNHVA
       ..:.::... :: ::.:. :.:::::: . ..::.:..::::::.:..  .:.:.::.::
NP_001 AIYFHPSTFHCARLAAGAGLQLVDAVLTGAVQNGLALVRPPGHHGQRAAANGFCVFNNVA
             100       110       120       130       140       150 

            240       250       260       270       280       290  
pF1KA0 VAARYAQQKHRIRRVLIVDWDVHHGQGTQFTFDQDPSVLYFSIHRYEQGRFWPHLKASNW
       .:: .:.::: ..:.:.:::::::::: :. :..:::::::: ::::.::::: :. :. 
NP_001 IAAAHAKQKHGLHRILVVDWDVHHGQGIQYLFEDDPSVLYFSWHRYEHGRFWPFLRESDA
             160       170       180       190       200       210 

            300       310       320       330       340       350  
pF1KA0 STTGFGQGQGYTINVPWNQVGMRDADYIAAFLHVLLPVALEFQPQLVLVAAGFDALQGDP
       ...: ::: :.:.:.::::::: .:::.:::::.:::.:.:                   
NP_001 DAVGRGQGLGFTVNLPWNQVGMGNADYVAAFLHLLLPLAFE-------------------
             220       230       240       250                     

            360       370       380       390       400       410  
pF1KA0 KGEMAATPAGFAQLTHLLMGLAGGKLILSLEGGYNLRALAEGVSASLHTLLGDPCPMLES
        :.: :::  ::.::.::. ::::..   :::::.:..:::.:  ...:::::: : : .
NP_001 -GQMQATPECFAHLTQLLQVLAGGRVCAVLEGGYHLESLAESVCMTVQTLLGDPAPPLSG
             260       270       280       290       300       310 

            420       430       440       450       460       470  
pF1KA0 PGAPCRSAQASVSCALEALEPFWEVLVRSTETVERDNMEEDNVEESEEEGPWEPPVLPIL
       : :::.::  :.. :  :  : :. : ..  :.    .  .   .: :  :  ::.::  
NP_001 PMAPCQSALESIQSARAAQAPHWKSLQQQDVTA----VPMSPSSHSPEGRP--PPLLP--
             320       330       340           350         360     

               480       490       500       510       520         
pF1KA0 TWPVLQ---SRTGLVYDQNMMNHCNLWDSHHPEVPQRILRIMCRLEELGLAGRCLTLTPR
         :: .   :  . . ::  .  :          :   .:    :    ..   :.: : 
NP_001 GGPVCKAAASAPSSLLDQPCL--C----------PAPSVRTAVALTTPDIT---LVLPPD
           370       380                   390       400           

     530        540       550       560       570       580        
pF1KA0 PAT-EAELLTCHSAEYVGHLRATEKMKTRELHRESSNFDSIYICPSTFACAQLATGAACR
           ::  :  ..  ..   :  :..  .:                    :  : :    
NP_001 VIQQEASALREETEAWA---RPHESLAREE--------------------ALTALGKLLY
      410       420          430                           440     

      590       600       610       620       630       640        
pF1KA0 LVEAVLSGEVLNGAAVVRPPGHHAEQDAACGFCFFNSVAVAARHAQTISGHALRILIVDW
       :....:.:.: .: :..  :.  :   ::       .. ::.:..  .:  : :.: :  
NP_001 LLDGMLDGQVNSGIAAT--PASAA---AA-------TLDVAVRRG--LSHGAQRLLCVA-
         450       460                   470         480       490 

      650       660       670       680       690       700        
pF1KA0 DVHHGNGTQHMFEDDPSVLYVSLHRYDHGTFFPMGDEGASSQIGRAAGTGFTVNVAWNGP
        . . .    . .:  : :.....          : :.:. ..       : :..    :
NP_001 -LGQLDRPPDLAHDGRS-LWLNIR----------GKEAAALSM-------FHVSTPL--P
               500        510                 520                  

      710       720       730       740       750       760        
pF1KA0 RMGDADYLAAWHRLVLPIAYEFNPELVLVSAGFDAARGDPLGGCQVSPEGYAHLTHLLMG
        :  . .:.    ::::.:: :.:.::::. :       :  : : .:.. : :. .: :
NP_001 VM-TGGFLSCILGLVLPLAYGFQPDLVLVALG-------PGHGLQ-GPHA-ALLAAMLRG
     530        540       550       560               570          

      770       780       790       800       810       820        
pF1KA0 LASGRIILILEGGYNLTSISESMAACTRSLLGDPPPLLTLPRPPLSGALASITETIQVHR
       ::.::.. .::     .:  .  .  .: : :. :: :                      
NP_001 LAGGRVLALLE----ENSTPQLAGILARVLNGEAPPSLGPSSVASPEDVQALMYLRGQLE
     580       590           600       610       620       630     

      830       840       850       860       870       880        
pF1KA0 RYWRSLRVMKVEDREGPSSSKLVTKKAPQPAKPRLAERMTTREKKVLEAGMGKVTSASFG
                                                                   
NP_001 PQWKMLQCHPHLVA                                              
         640                                                       

>>NP_001308159 (OMIM: 300272,300863) histone deacetylase  (146 aa)
 initn: 952 init1: 952 opt: 952  Z-score: 873.3  bits: 170.6 E(85289): 6.6e-42
Smith-Waterman score: 952; 100.0% identity (100.0% similar) in 145 aa overlap (1-145:1-145)

               10        20        30        40        50        60
pF1KA0 MTSTGQDSTTTRQRRSRQNPQSPPQDSSVTSKRNIKKGAVPRSIPNLAEVKKKGKMKKLG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MTSTGQDSTTTRQRRSRQNPQSPPQDSSVTSKRNIKKGAVPRSIPNLAEVKKKGKMKKLG
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KA0 QAMEEDLIVGLQGMDLNLEAEALAGTGLVLDEQLNEFHCLWDDSFPEGPERLHAIKEQLI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QAMEEDLIVGLQGMDLNLEAEALAGTGLVLDEQLNEFHCLWDDSFPEGPERLHAIKEQLI
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KA0 QEGLLDRCVSFQARFAEKEELMLVHSLEYIDLMETTQYMNEGELRVLADTYDSVYLHPNS
       :::::::::::::::::::::::::                                   
NP_001 QEGLLDRCVSFQARFAEKEELMLVHR                                  
              130       140                                        




1215 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Thu Nov  3 10:30:53 2016 done: Thu Nov  3 10:30:55 2016
 Total Scan time: 16.800 Total Display time:  0.310

Function used was FASTA [36.3.4 Apr, 2011]
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