Result of FASTA (omim) for pF1KA0580
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KA0580, 1704 aa
  1>>>pF1KA0580 1704 - 1704 aa - 1704 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 6.7708+/-0.000562; mu= 17.5330+/- 0.035
 mean_var=157.8473+/-34.016, 0's: 0 Z-trim(109.9): 451  B-trim: 593 in 1/53
 Lambda= 0.102084
 statistics sampled from 17607 (18123) to 17607 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.556), E-opt: 0.2 (0.212), width:  16
 Scan time: 16.830

The best scores are:                                      opt bits E(85289)
XP_016863188 (OMIM: 606645) PREDICTED: arf-GAP wit (1704) 11202 1664.3       0
NP_056045 (OMIM: 606645) arf-GAP with Rho-GAP doma (1704) 11202 1664.3       0
XP_016863187 (OMIM: 606645) PREDICTED: arf-GAP wit (1710) 10397 1545.8       0
XP_016863190 (OMIM: 606645) PREDICTED: arf-GAP wit (1659) 10086 1499.9       0
XP_016863191 (OMIM: 606645) PREDICTED: arf-GAP wit (1636) 8527 1270.3       0
XP_016863189 (OMIM: 606645) PREDICTED: arf-GAP wit (1681) 8527 1270.3       0
NP_056057 (OMIM: 606646) arf-GAP with Rho-GAP doma (1205) 2749 419.2 1.1e-115
NP_001035207 (OMIM: 606646) arf-GAP with Rho-GAP d (1450) 2749 419.3 1.2e-115
NP_001128662 (OMIM: 606646) arf-GAP with Rho-GAP d (1133) 1831 284.0 5.2e-75
XP_011535979 (OMIM: 606647) PREDICTED: arf-GAP wit (1349) 1700 264.8 3.8e-69
XP_005268556 (OMIM: 606647) PREDICTED: arf-GAP wit (1466) 1700 264.8   4e-69
NP_071926 (OMIM: 606647) arf-GAP with Rho-GAP doma (1544) 1700 264.9 4.2e-69
XP_005268554 (OMIM: 606647) PREDICTED: arf-GAP wit (1531) 1688 263.1 1.4e-68
XP_005268557 (OMIM: 606647) PREDICTED: arf-GAP wit ( 934) 1231 195.6 1.8e-48
XP_006714855 (OMIM: 606647) PREDICTED: arf-GAP wit (1473) 1231 195.8 2.5e-48
XP_005268555 (OMIM: 606647) PREDICTED: arf-GAP wit (1524) 1231 195.8 2.6e-48
NP_055585 (OMIM: 605476) arf-GAP with GTPase, ANK  ( 836)  340 64.3 5.4e-09
XP_005268683 (OMIM: 605476) PREDICTED: arf-GAP wit ( 856)  340 64.3 5.5e-09
XP_005268682 (OMIM: 605476) PREDICTED: arf-GAP wit (1172)  340 64.4 6.8e-09
XP_016874261 (OMIM: 605476) PREDICTED: arf-GAP wit (1192)  340 64.4 6.9e-09
NP_001116244 (OMIM: 605476) arf-GAP with GTPase, A (1192)  340 64.4 6.9e-09
NP_055729 (OMIM: 608651) arf-GAP with GTPase, ANK  ( 804)  325 62.1 2.4e-08
XP_005246116 (OMIM: 608651) PREDICTED: arf-GAP wit ( 808)  325 62.1 2.4e-08
NP_001032208 (OMIM: 608651) arf-GAP with GTPase, A ( 857)  325 62.1 2.5e-08
XP_006712298 (OMIM: 608651) PREDICTED: arf-GAP wit ( 882)  325 62.1 2.6e-08
XP_006712297 (OMIM: 608651) PREDICTED: arf-GAP wit ( 886)  325 62.1 2.6e-08
XP_011508851 (OMIM: 608651) PREDICTED: arf-GAP wit (1073)  325 62.2   3e-08
XP_011508850 (OMIM: 608651) PREDICTED: arf-GAP wit (1098)  325 62.2   3e-08
XP_016858771 (OMIM: 608651) PREDICTED: arf-GAP wit (1106)  325 62.2   3e-08
XP_011508849 (OMIM: 608651) PREDICTED: arf-GAP wit (1126)  325 62.2 3.1e-08
XP_006712300 (OMIM: 608651) PREDICTED: arf-GAP wit (1147)  325 62.2 3.1e-08
XP_006712302 (OMIM: 608651) PREDICTED: arf-GAP wit (1151)  325 62.2 3.1e-08
XP_016867224 (OMIM: 616813) PREDICTED: arf-GAP wit ( 462)  307 59.2   1e-07
XP_016867222 (OMIM: 616813) PREDICTED: arf-GAP wit ( 527)  307 59.2 1.1e-07
XP_005250000 (OMIM: 616813) PREDICTED: arf-GAP wit ( 565)  307 59.3 1.2e-07
NP_001268229 (OMIM: 616813) arf-GAP with GTPase, A ( 580)  307 59.3 1.2e-07
XP_016867223 (OMIM: 616813) PREDICTED: arf-GAP wit ( 580)  307 59.3 1.2e-07
XP_016867221 (OMIM: 616813) PREDICTED: arf-GAP wit ( 630)  307 59.3 1.3e-07
XP_011514082 (OMIM: 616813) PREDICTED: arf-GAP wit ( 683)  307 59.3 1.4e-07
NP_114152 (OMIM: 616813) arf-GAP with GTPase, ANK  ( 911)  307 59.5 1.7e-07
NP_008832 (OMIM: 604875) unconventional myosin-IXa (2548)  287 57.0 2.6e-06
XP_006720602 (OMIM: 604875) PREDICTED: unconventio (2619)  287 57.0 2.7e-06
XP_011519920 (OMIM: 604875) PREDICTED: unconventio (2620)  287 57.0 2.7e-06
XP_011510907 (OMIM: 607766) PREDICTED: arf-GAP wit ( 776)  276 54.8 3.5e-06
XP_011510908 (OMIM: 607766) PREDICTED: arf-GAP wit ( 776)  276 54.8 3.5e-06
XP_011510906 (OMIM: 607766) PREDICTED: arf-GAP wit ( 776)  276 54.8 3.5e-06
NP_036419 (OMIM: 607766) arf-GAP with coiled-coil, ( 778)  276 54.8 3.5e-06
XP_006713620 (OMIM: 607766) PREDICTED: arf-GAP wit ( 785)  276 54.8 3.5e-06
XP_016861538 (OMIM: 607766) PREDICTED: arf-GAP wit ( 806)  276 54.8 3.6e-06
XP_016861537 (OMIM: 607766) PREDICTED: arf-GAP wit ( 813)  276 54.9 3.6e-06


>>XP_016863188 (OMIM: 606645) PREDICTED: arf-GAP with Rh  (1704 aa)
 initn: 11202 init1: 11202 opt: 11202  Z-score: 8924.2  bits: 1664.3 E(85289):    0
Smith-Waterman score: 11202; 99.9% identity (100.0% similar) in 1704 aa overlap (1-1704:1-1704)

               10        20        30        40        50        60
pF1KA0 MSSVSEVNVDIKDFLMSINLEQYLLHFHESGFTTVKDCAAINDSLLQKIGISPTGHRRRI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MSSVSEVNVDIKDFLMSINLEQYLLHFHESGFTTVKDCAAINDSLLQKIGISPTGHRRRI
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KA0 LKQLQIILSKMQDIPIYANVHKTKKNDDPSKDYHVPSSDQNICIELSNSGSVQTSSPPQL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LKQLQIILSKMQDIPIYANVHKTKKNDDPSKDYHVPSSDQNICIELSNSGSVQTSSPPQL
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KA0 ETVRKNLEDSDASVERSQYPQSDDKLSPPKRDFPTAEEPHLNLGSLNDSLFGSDNIKIES
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ETVRKNLEDSDASVERSQYPQSDDKLSPPKRDFPTAEEPHLNLGSLNDSLFGSDNIKIES
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KA0 LITKKTVDHTVEEQQTEKVKLITENLSKLPNADSECLSFVGCSTSGTNSGNGTNGLLEGS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LITKKTVDHTVEEQQTEKVKLITENLSKLPNADSECLSFVGCSTSGTNSGNGTNGLLEGS
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KA0 PPSPFFKFQGEMIVNDLYVPSSPILAPVRSRSKLVSRPSRSFLLRHRPVPEIPGSTKGVS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PPSPFFKFQGEMIVNDLYVPSSPILAPVRSRSKLVSRPSRSFLLRHRPVPEIPGSTKGVS
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KA0 GSYFRERRNVATSTEKSVAWQNSNEENSSSIFPYGETFLFQRLENSKKRSIKNEFLTQGE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GSYFRERRNVATSTEKSVAWQNSNEENSSSIFPYGETFLFQRLENSKKRSIKNEFLTQGE
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KA0 ALKGEAATATNSFIIKSSIYDNRKEKISEDKVEDIWIPREDKNNFLIDTASESEYSTVEE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ALKGEAATATNSFIIKSSIYDNRKEKISEDKVEDIWIPREDKNNFLIDTASESEYSTVEE
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KA0 CFQSLRRKNSKASKSRTQKALILDSVNRHSYPLSSTSGNADSSAVSSQAISPYACFYGAS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CFQSLRRKNSKASKSRTQKALILDSVNRHSYPLSSTSGNADSSAVSSQAISPYACFYGAS
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KA0 AKKVKSGWLDKLSPQGKRMFQKRWVKFDGLSISYYNNEKEMYSKGIIPLSAISTVRVQGD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AKKVKSGWLDKLSPQGKRMFQKRWVKFDGLSISYYNNEKEMYSKGIIPLSAISTVRVQGD
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KA0 NKFEVVTTQRTFVFRVEKEEERNDWISILLNALKSQSLTSQSQAVVTPEKCGYLELRGYK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NKFEVVTTQRTFVFRVEKEEERNDWISILLNALKSQSLTSQSQAVVTPEKCGYLELRGYK
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KA0 AKIFTVLSGNSVWLCKNEQDFKSGLGITIIPMNVANVKQVDRTVKQSFEIITPYRSFSFT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AKIFTVLSGNSVWLCKNEQDFKSGLGITIIPMNVANVKQVDRTVKQSFEIITPYRSFSFT
              610       620       630       640       650       660

              670       680       690       700       710       720
pF1KA0 AETEKEKQDWIEAVQQSIAETLSDYEVAEKIWFNESNRSCADCKAPDPDWASINLCVVIC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AETEKEKQDWIEAVQQSIAETLSDYEVAEKIWFNESNRSCADCKAPDPDWASINLCVVIC
              670       680       690       700       710       720

              730       740       750       760       770       780
pF1KA0 KKCAGQHRSLGPKDSKVRSLKMDASIWSNELIELFIVIGNKRANDFWAGNLQKDEELHMD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KKCAGQHRSLGPKDSKVRSLKMDASIWSNELIELFIVIGNKRANDFWAGNLQKDEELHMD
              730       740       750       760       770       780

              790       800       810       820       830       840
pF1KA0 SPVEKRKNFITQKYKEGKFRKTLLASLTKEELNKALCAAVVKPDVLETMALLFSGADVMC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SPVEKRKNFITQKYKEGKFRKTLLASLTKEELNKALCAAVVKPDVLETMALLFSGADVMC
              790       800       810       820       830       840

              850       860       870       880       890       900
pF1KA0 ATGDPVHSTPYLLAKKAGQSLQMEFLYHNKFSDFPQHDIHSEGVLSQESSQSTFLCDFLY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ATGDPVHSTPYLLAKKAGQSLQMEFLYHNKFSDFPQHDIHSEGVLSQESSQSTFLCDFLY
              850       860       870       880       890       900

              910       920       930       940       950       960
pF1KA0 QAPSAASKLSSEKKLLEETNKKWCVLEGGFLSYYENDKSTTPNGTININEVICLAIHKED
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QAPSAASKLSSEKKLLEETNKKWCVLEGGFLSYYENDKSTTPNGTININEVICLAIHKED
              910       920       930       940       950       960

              970       980       990      1000      1010      1020
pF1KA0 FYLNTGPIFIFEIYLPSERVFLFGAETSQAQRKWTEAIAKHFVPLFAENLTEADYDLIGQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FYLNTGPIFIFEIYLPSERVFLFGAETSQAQRKWTEAIAKHFVPLFAENLTEADYDLIGQ
              970       980       990      1000      1010      1020

             1030      1040      1050      1060      1070      1080
pF1KA0 LFYKDCHALDQWRKGWFAMDKSSLHFCLQMQEVQGDRMHLRRLQELTISTMVQNGEKLDV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LFYKDCHALDQWRKGWFAMDKSSLHFCLQMQEVQGDRMHLRRLQELTISTMVQNGEKLDV
             1030      1040      1050      1060      1070      1080

             1090      1100      1110      1120      1130      1140
pF1KA0 LLLVEKGRTLYIHGHTKLDFTVWHTAIEKAAGTDGNALQDQQLSKNDVPIIVNSCIAFVT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LLLVEKGRTLYIHGHTKLDFTVWHTAIEKAAGTDGNALQDQQLSKNDVPIIVNSCIAFVT
             1090      1100      1110      1120      1130      1140

             1150      1160      1170      1180      1190      1200
pF1KA0 QYGLGCKYIYQKNGDPLHISELLESFKKDARSFKLRAGKHQLEDVTAVLKSFLSDIDDAL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QYGLGCKYIYQKNGDPLHISELLESFKKDARSFKLRAGKHQLEDVTAVLKSFLSDIDDAL
             1150      1160      1170      1180      1190      1200

             1210      1220      1230      1240      1250      1260
pF1KA0 LTKELYPYWISALDTQDDKERIKKYGAFIRSLPGVNRATLAAIIEHLYRVQKCSEINHMN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LTKELYPYWISALDTQDDKERIKKYGAFIRSLPGVNRATLAAIIEHLYRVQKCSEINHMN
             1210      1220      1230      1240      1250      1260

             1270      1280      1290      1300      1310      1320
pF1KA0 AHNLALVFSSCLFQTKGQTSEEVNVIEDLINNYVEIFEVKEDQVKQMDIENSFITKWKDT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AHNLALVFSSCLFQTKGQTSEEVNVIEDLINNYVEIFEVKEDQVKQMDIENSFITKWKDT
             1270      1280      1290      1300      1310      1320

             1330      1340      1350      1360      1370      1380
pF1KA0 QVSQAGDLLIEVYVERKEPDCSIIIRISPVMEAEELTNDILAIKNIIPTKGDIWATFEVI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QVSQAGDLLIEVYVERKEPDCSIIIRISPVMEAEELTNDILAIKNIIPTKGDIWATFEVI
             1330      1340      1350      1360      1370      1380

             1390      1400      1410      1420      1430      1440
pF1KA0 ENEELERPLHYKENVLEQVLRWSSLAEPGSAYLVVKRFLTADTIKHCSDRSTLGSIKEGI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ENEELERPLHYKENVLEQVLRWSSLAEPGSAYLVVKRFLTADTIKHCSDRSTLGSIKEGI
             1390      1400      1410      1420      1430      1440

             1450      1460      1470      1480      1490      1500
pF1KA0 LKIKEEPSKILSGNKFQDRYFVLRDGFLFLYKDVKSSKHDKMFSLSSMKFYRGVKKKMKP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LKIKEEPSKILSGNKFQDRYFVLRDGFLFLYKDVKSSKHDKMFSLSSMKFYRGVKKKMKP
             1450      1460      1470      1480      1490      1500

             1510      1520      1530      1540      1550      1560
pF1KA0 PTSWGLTAYSEKHHWHLCCDSSQTQTEWMTSIFIAQHEYDIWPPAGKERKRSITKNPKIG
       ::::::::::::::::::::::.:::::::::::::::::::::::::::::::::::::
XP_016 PTSWGLTAYSEKHHWHLCCDSSRTQTEWMTSIFIAQHEYDIWPPAGKERKRSITKNPKIG
             1510      1520      1530      1540      1550      1560

             1570      1580      1590      1600      1610      1620
pF1KA0 GLPLIPIQHEGNATLARKNIESARAELERLRLSEKCDKESVDSSLKERASMVAHCLEHKD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GLPLIPIQHEGNATLARKNIESARAELERLRLSEKCDKESVDSSLKERASMVAHCLEHKD
             1570      1580      1590      1600      1610      1620

             1630      1640      1650      1660      1670      1680
pF1KA0 DKLRNRPRKHRSFNCLEDTEPEAPLGQPKGHKGLKTLRKTEDRNSKATLDSDHKLPSRVI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DKLRNRPRKHRSFNCLEDTEPEAPLGQPKGHKGLKTLRKTEDRNSKATLDSDHKLPSRVI
             1630      1640      1650      1660      1670      1680

             1690      1700    
pF1KA0 EELNVVLQRSRTLPKELQDEQILK
       ::::::::::::::::::::::::
XP_016 EELNVVLQRSRTLPKELQDEQILK
             1690      1700    

>>NP_056045 (OMIM: 606645) arf-GAP with Rho-GAP domain,   (1704 aa)
 initn: 11202 init1: 11202 opt: 11202  Z-score: 8924.2  bits: 1664.3 E(85289):    0
Smith-Waterman score: 11202; 99.9% identity (100.0% similar) in 1704 aa overlap (1-1704:1-1704)

               10        20        30        40        50        60
pF1KA0 MSSVSEVNVDIKDFLMSINLEQYLLHFHESGFTTVKDCAAINDSLLQKIGISPTGHRRRI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 MSSVSEVNVDIKDFLMSINLEQYLLHFHESGFTTVKDCAAINDSLLQKIGISPTGHRRRI
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KA0 LKQLQIILSKMQDIPIYANVHKTKKNDDPSKDYHVPSSDQNICIELSNSGSVQTSSPPQL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 LKQLQIILSKMQDIPIYANVHKTKKNDDPSKDYHVPSSDQNICIELSNSGSVQTSSPPQL
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KA0 ETVRKNLEDSDASVERSQYPQSDDKLSPPKRDFPTAEEPHLNLGSLNDSLFGSDNIKIES
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 ETVRKNLEDSDASVERSQYPQSDDKLSPPKRDFPTAEEPHLNLGSLNDSLFGSDNIKIES
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KA0 LITKKTVDHTVEEQQTEKVKLITENLSKLPNADSECLSFVGCSTSGTNSGNGTNGLLEGS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 LITKKTVDHTVEEQQTEKVKLITENLSKLPNADSECLSFVGCSTSGTNSGNGTNGLLEGS
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KA0 PPSPFFKFQGEMIVNDLYVPSSPILAPVRSRSKLVSRPSRSFLLRHRPVPEIPGSTKGVS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 PPSPFFKFQGEMIVNDLYVPSSPILAPVRSRSKLVSRPSRSFLLRHRPVPEIPGSTKGVS
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KA0 GSYFRERRNVATSTEKSVAWQNSNEENSSSIFPYGETFLFQRLENSKKRSIKNEFLTQGE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 GSYFRERRNVATSTEKSVAWQNSNEENSSSIFPYGETFLFQRLENSKKRSIKNEFLTQGE
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KA0 ALKGEAATATNSFIIKSSIYDNRKEKISEDKVEDIWIPREDKNNFLIDTASESEYSTVEE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 ALKGEAATATNSFIIKSSIYDNRKEKISEDKVEDIWIPREDKNNFLIDTASESEYSTVEE
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KA0 CFQSLRRKNSKASKSRTQKALILDSVNRHSYPLSSTSGNADSSAVSSQAISPYACFYGAS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 CFQSLRRKNSKASKSRTQKALILDSVNRHSYPLSSTSGNADSSAVSSQAISPYACFYGAS
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KA0 AKKVKSGWLDKLSPQGKRMFQKRWVKFDGLSISYYNNEKEMYSKGIIPLSAISTVRVQGD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 AKKVKSGWLDKLSPQGKRMFQKRWVKFDGLSISYYNNEKEMYSKGIIPLSAISTVRVQGD
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KA0 NKFEVVTTQRTFVFRVEKEEERNDWISILLNALKSQSLTSQSQAVVTPEKCGYLELRGYK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 NKFEVVTTQRTFVFRVEKEEERNDWISILLNALKSQSLTSQSQAVVTPEKCGYLELRGYK
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KA0 AKIFTVLSGNSVWLCKNEQDFKSGLGITIIPMNVANVKQVDRTVKQSFEIITPYRSFSFT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 AKIFTVLSGNSVWLCKNEQDFKSGLGITIIPMNVANVKQVDRTVKQSFEIITPYRSFSFT
              610       620       630       640       650       660

              670       680       690       700       710       720
pF1KA0 AETEKEKQDWIEAVQQSIAETLSDYEVAEKIWFNESNRSCADCKAPDPDWASINLCVVIC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 AETEKEKQDWIEAVQQSIAETLSDYEVAEKIWFNESNRSCADCKAPDPDWASINLCVVIC
              670       680       690       700       710       720

              730       740       750       760       770       780
pF1KA0 KKCAGQHRSLGPKDSKVRSLKMDASIWSNELIELFIVIGNKRANDFWAGNLQKDEELHMD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 KKCAGQHRSLGPKDSKVRSLKMDASIWSNELIELFIVIGNKRANDFWAGNLQKDEELHMD
              730       740       750       760       770       780

              790       800       810       820       830       840
pF1KA0 SPVEKRKNFITQKYKEGKFRKTLLASLTKEELNKALCAAVVKPDVLETMALLFSGADVMC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 SPVEKRKNFITQKYKEGKFRKTLLASLTKEELNKALCAAVVKPDVLETMALLFSGADVMC
              790       800       810       820       830       840

              850       860       870       880       890       900
pF1KA0 ATGDPVHSTPYLLAKKAGQSLQMEFLYHNKFSDFPQHDIHSEGVLSQESSQSTFLCDFLY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 ATGDPVHSTPYLLAKKAGQSLQMEFLYHNKFSDFPQHDIHSEGVLSQESSQSTFLCDFLY
              850       860       870       880       890       900

              910       920       930       940       950       960
pF1KA0 QAPSAASKLSSEKKLLEETNKKWCVLEGGFLSYYENDKSTTPNGTININEVICLAIHKED
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 QAPSAASKLSSEKKLLEETNKKWCVLEGGFLSYYENDKSTTPNGTININEVICLAIHKED
              910       920       930       940       950       960

              970       980       990      1000      1010      1020
pF1KA0 FYLNTGPIFIFEIYLPSERVFLFGAETSQAQRKWTEAIAKHFVPLFAENLTEADYDLIGQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 FYLNTGPIFIFEIYLPSERVFLFGAETSQAQRKWTEAIAKHFVPLFAENLTEADYDLIGQ
              970       980       990      1000      1010      1020

             1030      1040      1050      1060      1070      1080
pF1KA0 LFYKDCHALDQWRKGWFAMDKSSLHFCLQMQEVQGDRMHLRRLQELTISTMVQNGEKLDV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 LFYKDCHALDQWRKGWFAMDKSSLHFCLQMQEVQGDRMHLRRLQELTISTMVQNGEKLDV
             1030      1040      1050      1060      1070      1080

             1090      1100      1110      1120      1130      1140
pF1KA0 LLLVEKGRTLYIHGHTKLDFTVWHTAIEKAAGTDGNALQDQQLSKNDVPIIVNSCIAFVT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 LLLVEKGRTLYIHGHTKLDFTVWHTAIEKAAGTDGNALQDQQLSKNDVPIIVNSCIAFVT
             1090      1100      1110      1120      1130      1140

             1150      1160      1170      1180      1190      1200
pF1KA0 QYGLGCKYIYQKNGDPLHISELLESFKKDARSFKLRAGKHQLEDVTAVLKSFLSDIDDAL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 QYGLGCKYIYQKNGDPLHISELLESFKKDARSFKLRAGKHQLEDVTAVLKSFLSDIDDAL
             1150      1160      1170      1180      1190      1200

             1210      1220      1230      1240      1250      1260
pF1KA0 LTKELYPYWISALDTQDDKERIKKYGAFIRSLPGVNRATLAAIIEHLYRVQKCSEINHMN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 LTKELYPYWISALDTQDDKERIKKYGAFIRSLPGVNRATLAAIIEHLYRVQKCSEINHMN
             1210      1220      1230      1240      1250      1260

             1270      1280      1290      1300      1310      1320
pF1KA0 AHNLALVFSSCLFQTKGQTSEEVNVIEDLINNYVEIFEVKEDQVKQMDIENSFITKWKDT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 AHNLALVFSSCLFQTKGQTSEEVNVIEDLINNYVEIFEVKEDQVKQMDIENSFITKWKDT
             1270      1280      1290      1300      1310      1320

             1330      1340      1350      1360      1370      1380
pF1KA0 QVSQAGDLLIEVYVERKEPDCSIIIRISPVMEAEELTNDILAIKNIIPTKGDIWATFEVI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 QVSQAGDLLIEVYVERKEPDCSIIIRISPVMEAEELTNDILAIKNIIPTKGDIWATFEVI
             1330      1340      1350      1360      1370      1380

             1390      1400      1410      1420      1430      1440
pF1KA0 ENEELERPLHYKENVLEQVLRWSSLAEPGSAYLVVKRFLTADTIKHCSDRSTLGSIKEGI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 ENEELERPLHYKENVLEQVLRWSSLAEPGSAYLVVKRFLTADTIKHCSDRSTLGSIKEGI
             1390      1400      1410      1420      1430      1440

             1450      1460      1470      1480      1490      1500
pF1KA0 LKIKEEPSKILSGNKFQDRYFVLRDGFLFLYKDVKSSKHDKMFSLSSMKFYRGVKKKMKP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 LKIKEEPSKILSGNKFQDRYFVLRDGFLFLYKDVKSSKHDKMFSLSSMKFYRGVKKKMKP
             1450      1460      1470      1480      1490      1500

             1510      1520      1530      1540      1550      1560
pF1KA0 PTSWGLTAYSEKHHWHLCCDSSQTQTEWMTSIFIAQHEYDIWPPAGKERKRSITKNPKIG
       ::::::::::::::::::::::.:::::::::::::::::::::::::::::::::::::
NP_056 PTSWGLTAYSEKHHWHLCCDSSRTQTEWMTSIFIAQHEYDIWPPAGKERKRSITKNPKIG
             1510      1520      1530      1540      1550      1560

             1570      1580      1590      1600      1610      1620
pF1KA0 GLPLIPIQHEGNATLARKNIESARAELERLRLSEKCDKESVDSSLKERASMVAHCLEHKD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 GLPLIPIQHEGNATLARKNIESARAELERLRLSEKCDKESVDSSLKERASMVAHCLEHKD
             1570      1580      1590      1600      1610      1620

             1630      1640      1650      1660      1670      1680
pF1KA0 DKLRNRPRKHRSFNCLEDTEPEAPLGQPKGHKGLKTLRKTEDRNSKATLDSDHKLPSRVI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 DKLRNRPRKHRSFNCLEDTEPEAPLGQPKGHKGLKTLRKTEDRNSKATLDSDHKLPSRVI
             1630      1640      1650      1660      1670      1680

             1690      1700    
pF1KA0 EELNVVLQRSRTLPKELQDEQILK
       ::::::::::::::::::::::::
NP_056 EELNVVLQRSRTLPKELQDEQILK
             1690      1700    

>>XP_016863187 (OMIM: 606645) PREDICTED: arf-GAP with Rh  (1710 aa)
 initn: 10397 init1: 10397 opt: 10397  Z-score: 8283.4  bits: 1545.8 E(85289):    0
Smith-Waterman score: 10397; 99.9% identity (100.0% similar) in 1581 aa overlap (1-1581:1-1581)

               10        20        30        40        50        60
pF1KA0 MSSVSEVNVDIKDFLMSINLEQYLLHFHESGFTTVKDCAAINDSLLQKIGISPTGHRRRI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MSSVSEVNVDIKDFLMSINLEQYLLHFHESGFTTVKDCAAINDSLLQKIGISPTGHRRRI
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KA0 LKQLQIILSKMQDIPIYANVHKTKKNDDPSKDYHVPSSDQNICIELSNSGSVQTSSPPQL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LKQLQIILSKMQDIPIYANVHKTKKNDDPSKDYHVPSSDQNICIELSNSGSVQTSSPPQL
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KA0 ETVRKNLEDSDASVERSQYPQSDDKLSPPKRDFPTAEEPHLNLGSLNDSLFGSDNIKIES
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ETVRKNLEDSDASVERSQYPQSDDKLSPPKRDFPTAEEPHLNLGSLNDSLFGSDNIKIES
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KA0 LITKKTVDHTVEEQQTEKVKLITENLSKLPNADSECLSFVGCSTSGTNSGNGTNGLLEGS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LITKKTVDHTVEEQQTEKVKLITENLSKLPNADSECLSFVGCSTSGTNSGNGTNGLLEGS
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KA0 PPSPFFKFQGEMIVNDLYVPSSPILAPVRSRSKLVSRPSRSFLLRHRPVPEIPGSTKGVS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PPSPFFKFQGEMIVNDLYVPSSPILAPVRSRSKLVSRPSRSFLLRHRPVPEIPGSTKGVS
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KA0 GSYFRERRNVATSTEKSVAWQNSNEENSSSIFPYGETFLFQRLENSKKRSIKNEFLTQGE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GSYFRERRNVATSTEKSVAWQNSNEENSSSIFPYGETFLFQRLENSKKRSIKNEFLTQGE
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KA0 ALKGEAATATNSFIIKSSIYDNRKEKISEDKVEDIWIPREDKNNFLIDTASESEYSTVEE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ALKGEAATATNSFIIKSSIYDNRKEKISEDKVEDIWIPREDKNNFLIDTASESEYSTVEE
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KA0 CFQSLRRKNSKASKSRTQKALILDSVNRHSYPLSSTSGNADSSAVSSQAISPYACFYGAS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CFQSLRRKNSKASKSRTQKALILDSVNRHSYPLSSTSGNADSSAVSSQAISPYACFYGAS
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KA0 AKKVKSGWLDKLSPQGKRMFQKRWVKFDGLSISYYNNEKEMYSKGIIPLSAISTVRVQGD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AKKVKSGWLDKLSPQGKRMFQKRWVKFDGLSISYYNNEKEMYSKGIIPLSAISTVRVQGD
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KA0 NKFEVVTTQRTFVFRVEKEEERNDWISILLNALKSQSLTSQSQAVVTPEKCGYLELRGYK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NKFEVVTTQRTFVFRVEKEEERNDWISILLNALKSQSLTSQSQAVVTPEKCGYLELRGYK
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KA0 AKIFTVLSGNSVWLCKNEQDFKSGLGITIIPMNVANVKQVDRTVKQSFEIITPYRSFSFT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AKIFTVLSGNSVWLCKNEQDFKSGLGITIIPMNVANVKQVDRTVKQSFEIITPYRSFSFT
              610       620       630       640       650       660

              670       680       690       700       710       720
pF1KA0 AETEKEKQDWIEAVQQSIAETLSDYEVAEKIWFNESNRSCADCKAPDPDWASINLCVVIC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AETEKEKQDWIEAVQQSIAETLSDYEVAEKIWFNESNRSCADCKAPDPDWASINLCVVIC
              670       680       690       700       710       720

              730       740       750       760       770       780
pF1KA0 KKCAGQHRSLGPKDSKVRSLKMDASIWSNELIELFIVIGNKRANDFWAGNLQKDEELHMD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KKCAGQHRSLGPKDSKVRSLKMDASIWSNELIELFIVIGNKRANDFWAGNLQKDEELHMD
              730       740       750       760       770       780

              790       800       810       820       830       840
pF1KA0 SPVEKRKNFITQKYKEGKFRKTLLASLTKEELNKALCAAVVKPDVLETMALLFSGADVMC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SPVEKRKNFITQKYKEGKFRKTLLASLTKEELNKALCAAVVKPDVLETMALLFSGADVMC
              790       800       810       820       830       840

              850       860       870       880       890       900
pF1KA0 ATGDPVHSTPYLLAKKAGQSLQMEFLYHNKFSDFPQHDIHSEGVLSQESSQSTFLCDFLY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ATGDPVHSTPYLLAKKAGQSLQMEFLYHNKFSDFPQHDIHSEGVLSQESSQSTFLCDFLY
              850       860       870       880       890       900

              910       920       930       940       950       960
pF1KA0 QAPSAASKLSSEKKLLEETNKKWCVLEGGFLSYYENDKSTTPNGTININEVICLAIHKED
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QAPSAASKLSSEKKLLEETNKKWCVLEGGFLSYYENDKSTTPNGTININEVICLAIHKED
              910       920       930       940       950       960

              970       980       990      1000      1010      1020
pF1KA0 FYLNTGPIFIFEIYLPSERVFLFGAETSQAQRKWTEAIAKHFVPLFAENLTEADYDLIGQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FYLNTGPIFIFEIYLPSERVFLFGAETSQAQRKWTEAIAKHFVPLFAENLTEADYDLIGQ
              970       980       990      1000      1010      1020

             1030      1040      1050      1060      1070      1080
pF1KA0 LFYKDCHALDQWRKGWFAMDKSSLHFCLQMQEVQGDRMHLRRLQELTISTMVQNGEKLDV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LFYKDCHALDQWRKGWFAMDKSSLHFCLQMQEVQGDRMHLRRLQELTISTMVQNGEKLDV
             1030      1040      1050      1060      1070      1080

             1090      1100      1110      1120      1130      1140
pF1KA0 LLLVEKGRTLYIHGHTKLDFTVWHTAIEKAAGTDGNALQDQQLSKNDVPIIVNSCIAFVT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LLLVEKGRTLYIHGHTKLDFTVWHTAIEKAAGTDGNALQDQQLSKNDVPIIVNSCIAFVT
             1090      1100      1110      1120      1130      1140

             1150      1160      1170      1180      1190      1200
pF1KA0 QYGLGCKYIYQKNGDPLHISELLESFKKDARSFKLRAGKHQLEDVTAVLKSFLSDIDDAL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QYGLGCKYIYQKNGDPLHISELLESFKKDARSFKLRAGKHQLEDVTAVLKSFLSDIDDAL
             1150      1160      1170      1180      1190      1200

             1210      1220      1230      1240      1250      1260
pF1KA0 LTKELYPYWISALDTQDDKERIKKYGAFIRSLPGVNRATLAAIIEHLYRVQKCSEINHMN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LTKELYPYWISALDTQDDKERIKKYGAFIRSLPGVNRATLAAIIEHLYRVQKCSEINHMN
             1210      1220      1230      1240      1250      1260

             1270      1280      1290      1300      1310      1320
pF1KA0 AHNLALVFSSCLFQTKGQTSEEVNVIEDLINNYVEIFEVKEDQVKQMDIENSFITKWKDT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AHNLALVFSSCLFQTKGQTSEEVNVIEDLINNYVEIFEVKEDQVKQMDIENSFITKWKDT
             1270      1280      1290      1300      1310      1320

             1330      1340      1350      1360      1370      1380
pF1KA0 QVSQAGDLLIEVYVERKEPDCSIIIRISPVMEAEELTNDILAIKNIIPTKGDIWATFEVI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QVSQAGDLLIEVYVERKEPDCSIIIRISPVMEAEELTNDILAIKNIIPTKGDIWATFEVI
             1330      1340      1350      1360      1370      1380

             1390      1400      1410      1420      1430      1440
pF1KA0 ENEELERPLHYKENVLEQVLRWSSLAEPGSAYLVVKRFLTADTIKHCSDRSTLGSIKEGI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ENEELERPLHYKENVLEQVLRWSSLAEPGSAYLVVKRFLTADTIKHCSDRSTLGSIKEGI
             1390      1400      1410      1420      1430      1440

             1450      1460      1470      1480      1490      1500
pF1KA0 LKIKEEPSKILSGNKFQDRYFVLRDGFLFLYKDVKSSKHDKMFSLSSMKFYRGVKKKMKP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LKIKEEPSKILSGNKFQDRYFVLRDGFLFLYKDVKSSKHDKMFSLSSMKFYRGVKKKMKP
             1450      1460      1470      1480      1490      1500

             1510      1520      1530      1540      1550      1560
pF1KA0 PTSWGLTAYSEKHHWHLCCDSSQTQTEWMTSIFIAQHEYDIWPPAGKERKRSITKNPKIG
       ::::::::::::::::::::::.:::::::::::::::::::::::::::::::::::::
XP_016 PTSWGLTAYSEKHHWHLCCDSSRTQTEWMTSIFIAQHEYDIWPPAGKERKRSITKNPKIG
             1510      1520      1530      1540      1550      1560

             1570      1580      1590      1600      1610      1620
pF1KA0 GLPLIPIQHEGNATLARKNIESARAELERLRLSEKCDKESVDSSLKERASMVAHCLEHKD
       :::::::::::::::::::::                                       
XP_016 GLPLIPIQHEGNATLARKNIERDPCEHTSSHLEASGSHMVGAGMNWNLDRTSSKLPTTSI
             1570      1580      1590      1600      1610      1620

>>XP_016863190 (OMIM: 606645) PREDICTED: arf-GAP with Rh  (1659 aa)
 initn: 10086 init1: 10086 opt: 10086  Z-score: 8036.0  bits: 1499.9 E(85289):    0
Smith-Waterman score: 10791; 97.3% identity (97.4% similar) in 1704 aa overlap (1-1704:1-1659)

               10        20        30        40        50        60
pF1KA0 MSSVSEVNVDIKDFLMSINLEQYLLHFHESGFTTVKDCAAINDSLLQKIGISPTGHRRRI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MSSVSEVNVDIKDFLMSINLEQYLLHFHESGFTTVKDCAAINDSLLQKIGISPTGHRRRI
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KA0 LKQLQIILSKMQDIPIYANVHKTKKNDDPSKDYHVPSSDQNICIELSNSGSVQTSSPPQL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LKQLQIILSKMQDIPIYANVHKTKKNDDPSKDYHVPSSDQNICIELSNSGSVQTSSPPQL
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KA0 ETVRKNLEDSDASVERSQYPQSDDKLSPPKRDFPTAEEPHLNLGSLNDSLFGSDNIKIES
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ETVRKNLEDSDASVERSQYPQSDDKLSPPKRDFPTAEEPHLNLGSLNDSLFGSDNIKIES
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KA0 LITKKTVDHTVEEQQTEKVKLITENLSKLPNADSECLSFVGCSTSGTNSGNGTNGLLEGS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LITKKTVDHTVEEQQTEKVKLITENLSKLPNADSECLSFVGCSTSGTNSGNGTNGLLEGS
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KA0 PPSPFFKFQGEMIVNDLYVPSSPILAPVRSRSKLVSRPSRSFLLRHRPVPEIPGSTKGVS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PPSPFFKFQGEMIVNDLYVPSSPILAPVRSRSKLVSRPSRSFLLRHRPVPEIPGSTKGVS
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KA0 GSYFRERRNVATSTEKSVAWQNSNEENSSSIFPYGETFLFQRLENSKKRSIKNEFLTQGE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GSYFRERRNVATSTEKSVAWQNSNEENSSSIFPYGETFLFQRLENSKKRSIKNEFLTQGE
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KA0 ALKGEAATATNSFIIKSSIYDNRKEKISEDKVEDIWIPREDKNNFLIDTASESEYSTVEE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ALKGEAATATNSFIIKSSIYDNRKEKISEDKVEDIWIPREDKNNFLIDTASESEYSTVEE
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KA0 CFQSLRRKNSKASKSRTQKALILDSVNRHSYPLSSTSGNADSSAVSSQAISPYACFYGAS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CFQSLRRKNSKASKSRTQKALILDSVNRHSYPLSSTSGNADSSAVSSQAISPYACFYGAS
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KA0 AKKVKSGWLDKLSPQGKRMFQKRWVKFDGLSISYYNNEKEMYSKGIIPLSAISTVRVQGD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AKKVKSGWLDKLSPQGKRMFQKRWVKFDGLSISYYNNEKEMYSKGIIPLSAISTVRVQGD
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KA0 NKFEVVTTQRTFVFRVEKEEERNDWISILLNALKSQSLTSQSQAVVTPEKCGYLELRGYK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NKFEVVTTQRTFVFRVEKEEERNDWISILLNALKSQSLTSQSQAVVTPEKCGYLELRGYK
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KA0 AKIFTVLSGNSVWLCKNEQDFKSGLGITIIPMNVANVKQVDRTVKQSFEIITPYRSFSFT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AKIFTVLSGNSVWLCKNEQDFKSGLGITIIPMNVANVKQVDRTVKQSFEIITPYRSFSFT
              610       620       630       640       650       660

              670       680       690       700       710       720
pF1KA0 AETEKEKQDWIEAVQQSIAETLSDYEVAEKIWFNESNRSCADCKAPDPDWASINLCVVIC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AETEKEKQDWIEAVQQSIAETLSDYEVAEKIWFNESNRSCADCKAPDPDWASINLCVVIC
              670       680       690       700       710       720

              730       740       750       760       770       780
pF1KA0 KKCAGQHRSLGPKDSKVRSLKMDASIWSNELIELFIVIGNKRANDFWAGNLQKDEELHMD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KKCAGQHRSLGPKDSKVRSLKMDASIWSNELIELFIVIGNKRANDFWAGNLQKDEELHMD
              730       740       750       760       770       780

              790       800       810       820       830       840
pF1KA0 SPVEKRKNFITQKYKEGKFRKTLLASLTKEELNKALCAAVVKPDVLETMALLFSGADVMC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SPVEKRKNFITQKYKEGKFRKTLLASLTKEELNKALCAAVVKPDVLETMALLFSGADVMC
              790       800       810       820       830       840

              850       860       870       880       890       900
pF1KA0 ATGDPVHSTPYLLAKKAGQSLQMEFLYHNKFSDFPQHDIHSEGVLSQESSQSTFLCDFLY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ATGDPVHSTPYLLAKKAGQSLQMEFLYHNKFSDFPQHDIHSEGVLSQESSQSTFLCDFLY
              850       860       870       880       890       900

              910       920       930       940       950       960
pF1KA0 QAPSAASKLSSEKKLLEETNKKWCVLEGGFLSYYENDKSTTPNGTININEVICLAIHKED
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QAPSAASKLSSEKKLLEETNKKWCVLEGGFLSYYENDKSTTPNGTININEVICLAIHKED
              910       920       930       940       950       960

              970       980       990      1000      1010      1020
pF1KA0 FYLNTGPIFIFEIYLPSERVFLFGAETSQAQRKWTEAIAKHFVPLFAENLTEADYDLIGQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FYLNTGPIFIFEIYLPSERVFLFGAETSQAQRKWTEAIAKHFVPLFAENLTEADYDLIGQ
              970       980       990      1000      1010      1020

             1030      1040      1050      1060      1070      1080
pF1KA0 LFYKDCHALDQWRKGWFAMDKSSLHFCLQMQEVQGDRMHLRRLQELTISTMVQNGEKLDV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LFYKDCHALDQWRKGWFAMDKSSLHFCLQMQEVQGDRMHLRRLQELTISTMVQNGEKLDV
             1030      1040      1050      1060      1070      1080

             1090      1100      1110      1120      1130      1140
pF1KA0 LLLVEKGRTLYIHGHTKLDFTVWHTAIEKAAGTDGNALQDQQLSKNDVPIIVNSCIAFVT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LLLVEKGRTLYIHGHTKLDFTVWHTAIEKAAGTDGNALQDQQLSKNDVPIIVNSCIAFVT
             1090      1100      1110      1120      1130      1140

             1150      1160      1170      1180      1190      1200
pF1KA0 QYGLGCKYIYQKNGDPLHISELLESFKKDARSFKLRAGKHQLEDVTAVLKSFLSDIDDAL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QYGLGCKYIYQKNGDPLHISELLESFKKDARSFKLRAGKHQLEDVTAVLKSFLSDIDDAL
             1150      1160      1170      1180      1190      1200

             1210      1220      1230      1240      1250      1260
pF1KA0 LTKELYPYWISALDTQDDKERIKKYGAFIRSLPGVNRATLAAIIEHLYRVQKCSEINHMN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LTKELYPYWISALDTQDDKERIKKYGAFIRSLPGVNRATLAAIIEHLYRVQKCSEINHMN
             1210      1220      1230      1240      1250      1260

             1270      1280      1290      1300      1310      1320
pF1KA0 AHNLALVFSSCLFQTKGQTSEEVNVIEDLINNYVEIFEVKEDQVKQMDIENSFITKWKDT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AHNLALVFSSCLFQTKGQTSEEVNVIEDLINNYVEIFEVKEDQVKQMDIENSFITKWKDT
             1270      1280      1290      1300      1310      1320

             1330      1340      1350      1360      1370      1380
pF1KA0 QVSQAGDLLIEVYVERKEPDCSIIIRISPVMEAEELTNDILAIKNIIPTKGDIWATFEVI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QVSQAGDLLIEVYVERKEPDCSIIIRISPVMEAEELTNDILAIKNIIPTKGDIWATFEVI
             1330      1340      1350      1360      1370      1380

             1390      1400      1410      1420      1430      1440
pF1KA0 ENEELERPLHYKENVLEQVLRWSSLAEPGSAYLVVKRFLTADTIKHCSDRSTLGSIKEGI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ENEELERPLHYKENVLEQVLRWSSLAEPGSAYLVVKRFLTADTIKHCSDRSTLGSIKEGI
             1390      1400      1410      1420      1430      1440

             1450      1460      1470      1480      1490      1500
pF1KA0 LKIKEEPSKILSGNKFQDRYFVLRDGFLFLYKDVKSSKHDKMFSLSSMKFYRGVKKKMKP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LKIKEEPSKILSGNKFQDRYFVLRDGFLFLYKDVKSSKHDKMFSLSSMKFYRGVKKKMKP
             1450      1460      1470      1480      1490      1500

             1510      1520      1530      1540      1550      1560
pF1KA0 PTSWGLTAYSEKHHWHLCCDSSQTQTEWMTSIFIAQHEYDIWPPAGKERKRSITKNPKIG
       ::::::::::::::::::::::.:::::::::::::                        
XP_016 PTSWGLTAYSEKHHWHLCCDSSRTQTEWMTSIFIAQ------------------------
             1510      1520      1530                              

             1570      1580      1590      1600      1610      1620
pF1KA0 GLPLIPIQHEGNATLARKNIESARAELERLRLSEKCDKESVDSSLKERASMVAHCLEHKD
                            :::::::::::::::::::::::::::::::::::::::
XP_016 ---------------------SARAELERLRLSEKCDKESVDSSLKERASMVAHCLEHKD
                            1540      1550      1560      1570     

             1630      1640      1650      1660      1670      1680
pF1KA0 DKLRNRPRKHRSFNCLEDTEPEAPLGQPKGHKGLKTLRKTEDRNSKATLDSDHKLPSRVI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DKLRNRPRKHRSFNCLEDTEPEAPLGQPKGHKGLKTLRKTEDRNSKATLDSDHKLPSRVI
        1580      1590      1600      1610      1620      1630     

             1690      1700    
pF1KA0 EELNVVLQRSRTLPKELQDEQILK
       ::::::::::::::::::::::::
XP_016 EELNVVLQRSRTLPKELQDEQILK
        1640      1650         

>>XP_016863191 (OMIM: 606645) PREDICTED: arf-GAP with Rh  (1636 aa)
 initn: 9314 init1: 8521 opt: 8527  Z-score: 6795.2  bits: 1270.3 E(85289):    0
Smith-Waterman score: 10582; 96.0% identity (96.0% similar) in 1704 aa overlap (1-1704:1-1636)

               10        20        30        40        50        60
pF1KA0 MSSVSEVNVDIKDFLMSINLEQYLLHFHESGFTTVKDCAAINDSLLQKIGISPTGHRRRI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MSSVSEVNVDIKDFLMSINLEQYLLHFHESGFTTVKDCAAINDSLLQKIGISPTGHRRRI
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KA0 LKQLQIILSKMQDIPIYANVHKTKKNDDPSKDYHVPSSDQNICIELSNSGSVQTSSPPQL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LKQLQIILSKMQDIPIYANVHKTKKNDDPSKDYHVPSSDQNICIELSNSGSVQTSSPPQL
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KA0 ETVRKNLEDSDASVERSQYPQSDDKLSPPKRDFPTAEEPHLNLGSLNDSLFGSDNIKIES
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ETVRKNLEDSDASVERSQYPQSDDKLSPPKRDFPTAEEPHLNLGSLNDSLFGSDNIKIES
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KA0 LITKKTVDHTVEEQQTEKVKLITENLSKLPNADSECLSFVGCSTSGTNSGNGTNGLLEGS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LITKKTVDHTVEEQQTEKVKLITENLSKLPNADSECLSFVGCSTSGTNSGNGTNGLLEGS
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KA0 PPSPFFKFQGEMIVNDLYVPSSPILAPVRSRSKLVSRPSRSFLLRHRPVPEIPGSTKGVS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PPSPFFKFQGEMIVNDLYVPSSPILAPVRSRSKLVSRPSRSFLLRHRPVPEIPGSTKGVS
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KA0 GSYFRERRNVATSTEKSVAWQNSNEENSSSIFPYGETFLFQRLENSKKRSIKNEFLTQGE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GSYFRERRNVATSTEKSVAWQNSNEENSSSIFPYGETFLFQRLENSKKRSIKNEFLTQGE
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KA0 ALKGEAATATNSFIIKSSIYDNRKEKISEDKVEDIWIPREDKNNFLIDTASESEYSTVEE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ALKGEAATATNSFIIKSSIYDNRKEKISEDKVEDIWIPREDKNNFLIDTASESEYSTVEE
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KA0 CFQSLRRKNSKASKSRTQKALILDSVNRHSYPLSSTSGNADSSAVSSQAISPYACFYGAS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CFQSLRRKNSKASKSRTQKALILDSVNRHSYPLSSTSGNADSSAVSSQAISPYACFYGAS
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KA0 AKKVKSGWLDKLSPQGKRMFQKRWVKFDGLSISYYNNEKEMYSKGIIPLSAISTVRVQGD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AKKVKSGWLDKLSPQGKRMFQKRWVKFDGLSISYYNNEKEMYSKGIIPLSAISTVRVQGD
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KA0 NKFEVVTTQRTFVFRVEKEEERNDWISILLNALKSQSLTSQSQAVVTPEKCGYLELRGYK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NKFEVVTTQRTFVFRVEKEEERNDWISILLNALKSQSLTSQSQAVVTPEKCGYLELRGYK
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KA0 AKIFTVLSGNSVWLCKNEQDFKSGLGITIIPMNVANVKQVDRTVKQSFEIITPYRSFSFT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AKIFTVLSGNSVWLCKNEQDFKSGLGITIIPMNVANVKQVDRTVKQSFEIITPYRSFSFT
              610       620       630       640       650       660

              670       680       690       700       710       720
pF1KA0 AETEKEKQDWIEAVQQSIAETLSDYEVAEKIWFNESNRSCADCKAPDPDWASINLCVVIC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AETEKEKQDWIEAVQQSIAETLSDYEVAEKIWFNESNRSCADCKAPDPDWASINLCVVIC
              670       680       690       700       710       720

              730       740       750       760       770       780
pF1KA0 KKCAGQHRSLGPKDSKVRSLKMDASIWSNELIELFIVIGNKRANDFWAGNLQKDEELHMD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KKCAGQHRSLGPKDSKVRSLKMDASIWSNELIELFIVIGNKRANDFWAGNLQKDEELHMD
              730       740       750       760       770       780

              790       800       810       820       830       840
pF1KA0 SPVEKRKNFITQKYKEGKFRKTLLASLTKEELNKALCAAVVKPDVLETMALLFSGADVMC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SPVEKRKNFITQKYKEGKFRKTLLASLTKEELNKALCAAVVKPDVLETMALLFSGADVMC
              790       800       810       820       830       840

              850       860       870       880       890       900
pF1KA0 ATGDPVHSTPYLLAKKAGQSLQMEFLYHNKFSDFPQHDIHSEGVLSQESSQSTFLCDFLY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ATGDPVHSTPYLLAKKAGQSLQMEFLYHNKFSDFPQHDIHSEGVLSQESSQSTFLCDFLY
              850       860       870       880       890       900

              910       920       930       940       950       960
pF1KA0 QAPSAASKLSSEKKLLEETNKKWCVLEGGFLSYYENDKSTTPNGTININEVICLAIHKED
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QAPSAASKLSSEKKLLEETNKKWCVLEGGFLSYYENDKSTTPNGTININEVICLAIHKED
              910       920       930       940       950       960

              970       980       990      1000      1010      1020
pF1KA0 FYLNTGPIFIFEIYLPSERVFLFGAETSQAQRKWTEAIAKHFVPLFAENLTEADYDLIGQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FYLNTGPIFIFEIYLPSERVFLFGAETSQAQRKWTEAIAKHFVPLFAENLTEADYDLIGQ
              970       980       990      1000      1010      1020

             1030      1040      1050      1060      1070      1080
pF1KA0 LFYKDCHALDQWRKGWFAMDKSSLHFCLQMQEVQGDRMHLRRLQELTISTMVQNGEKLDV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LFYKDCHALDQWRKGWFAMDKSSLHFCLQMQEVQGDRMHLRRLQELTISTMVQNGEKLDV
             1030      1040      1050      1060      1070      1080

             1090      1100      1110      1120      1130      1140
pF1KA0 LLLVEKGRTLYIHGHTKLDFTVWHTAIEKAAGTDGNALQDQQLSKNDVPIIVNSCIAFVT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LLLVEKGRTLYIHGHTKLDFTVWHTAIEKAAGTDGNALQDQQLSKNDVPIIVNSCIAFVT
             1090      1100      1110      1120      1130      1140

             1150      1160      1170      1180      1190      1200
pF1KA0 QYGLGCKYIYQKNGDPLHISELLESFKKDARSFKLRAGKHQLEDVTAVLKSFLSDIDDAL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QYGLGCKYIYQKNGDPLHISELLESFKKDARSFKLRAGKHQLEDVTAVLKSFLSDIDDAL
             1150      1160      1170      1180      1190      1200

             1210      1220      1230      1240      1250      1260
pF1KA0 LTKELYPYWISALDTQDDKERIKKYGAFIRSLPGVNRATLAAIIEHLYRVQKCSEINHMN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LTKELYPYWISALDTQDDKERIKKYGAFIRSLPGVNRATLAAIIEHLYRVQKCSEINHMN
             1210      1220      1230      1240      1250      1260

             1270      1280      1290      1300      1310      1320
pF1KA0 AHNLALVFSSCLFQTKGQTSEEVNVIEDLINNYVEIFEVKEDQVKQMDIENSFITKWKDT
       :::::::::::::::::::::::::::::::::::::::                     
XP_016 AHNLALVFSSCLFQTKGQTSEEVNVIEDLINNYVEIFEV---------------------
             1270      1280      1290                              

             1330      1340      1350      1360      1370      1380
pF1KA0 QVSQAGDLLIEVYVERKEPDCSIIIRISPVMEAEELTNDILAIKNIIPTKGDIWATFEVI
         ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 --SQAGDLLIEVYVERKEPDCSIIIRISPVMEAEELTNDILAIKNIIPTKGDIWATFEVI
      1300      1310      1320      1330      1340      1350       

             1390      1400      1410      1420      1430      1440
pF1KA0 ENEELERPLHYKENVLEQVLRWSSLAEPGSAYLVVKRFLTADTIKHCSDRSTLGSIKEGI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ENEELERPLHYKENVLEQVLRWSSLAEPGSAYLVVKRFLTADTIKHCSDRSTLGSIKEGI
      1360      1370      1380      1390      1400      1410       

             1450      1460      1470      1480      1490      1500
pF1KA0 LKIKEEPSKILSGNKFQDRYFVLRDGFLFLYKDVKSSKHDKMFSLSSMKFYRGVKKKMKP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LKIKEEPSKILSGNKFQDRYFVLRDGFLFLYKDVKSSKHDKMFSLSSMKFYRGVKKKMKP
      1420      1430      1440      1450      1460      1470       

             1510      1520      1530      1540      1550      1560
pF1KA0 PTSWGLTAYSEKHHWHLCCDSSQTQTEWMTSIFIAQHEYDIWPPAGKERKRSITKNPKIG
       ::::::::::::::::::::::.:::::::::::::                        
XP_016 PTSWGLTAYSEKHHWHLCCDSSRTQTEWMTSIFIAQ------------------------
      1480      1490      1500      1510                           

             1570      1580      1590      1600      1610      1620
pF1KA0 GLPLIPIQHEGNATLARKNIESARAELERLRLSEKCDKESVDSSLKERASMVAHCLEHKD
                            :::::::::::::::::::::::::::::::::::::::
XP_016 ---------------------SARAELERLRLSEKCDKESVDSSLKERASMVAHCLEHKD
                               1520      1530      1540      1550  

             1630      1640      1650      1660      1670      1680
pF1KA0 DKLRNRPRKHRSFNCLEDTEPEAPLGQPKGHKGLKTLRKTEDRNSKATLDSDHKLPSRVI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DKLRNRPRKHRSFNCLEDTEPEAPLGQPKGHKGLKTLRKTEDRNSKATLDSDHKLPSRVI
           1560      1570      1580      1590      1600      1610  

             1690      1700    
pF1KA0 EELNVVLQRSRTLPKELQDEQILK
       ::::::::::::::::::::::::
XP_016 EELNVVLQRSRTLPKELQDEQILK
           1620      1630      

>>XP_016863189 (OMIM: 606645) PREDICTED: arf-GAP with Rh  (1681 aa)
 initn: 8521 init1: 8521 opt: 8527  Z-score: 6795.1  bits: 1270.3 E(85289):    0
Smith-Waterman score: 10993; 98.6% identity (98.7% similar) in 1704 aa overlap (1-1704:1-1681)

               10        20        30        40        50        60
pF1KA0 MSSVSEVNVDIKDFLMSINLEQYLLHFHESGFTTVKDCAAINDSLLQKIGISPTGHRRRI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MSSVSEVNVDIKDFLMSINLEQYLLHFHESGFTTVKDCAAINDSLLQKIGISPTGHRRRI
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KA0 LKQLQIILSKMQDIPIYANVHKTKKNDDPSKDYHVPSSDQNICIELSNSGSVQTSSPPQL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LKQLQIILSKMQDIPIYANVHKTKKNDDPSKDYHVPSSDQNICIELSNSGSVQTSSPPQL
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KA0 ETVRKNLEDSDASVERSQYPQSDDKLSPPKRDFPTAEEPHLNLGSLNDSLFGSDNIKIES
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ETVRKNLEDSDASVERSQYPQSDDKLSPPKRDFPTAEEPHLNLGSLNDSLFGSDNIKIES
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KA0 LITKKTVDHTVEEQQTEKVKLITENLSKLPNADSECLSFVGCSTSGTNSGNGTNGLLEGS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LITKKTVDHTVEEQQTEKVKLITENLSKLPNADSECLSFVGCSTSGTNSGNGTNGLLEGS
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KA0 PPSPFFKFQGEMIVNDLYVPSSPILAPVRSRSKLVSRPSRSFLLRHRPVPEIPGSTKGVS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PPSPFFKFQGEMIVNDLYVPSSPILAPVRSRSKLVSRPSRSFLLRHRPVPEIPGSTKGVS
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KA0 GSYFRERRNVATSTEKSVAWQNSNEENSSSIFPYGETFLFQRLENSKKRSIKNEFLTQGE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GSYFRERRNVATSTEKSVAWQNSNEENSSSIFPYGETFLFQRLENSKKRSIKNEFLTQGE
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KA0 ALKGEAATATNSFIIKSSIYDNRKEKISEDKVEDIWIPREDKNNFLIDTASESEYSTVEE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ALKGEAATATNSFIIKSSIYDNRKEKISEDKVEDIWIPREDKNNFLIDTASESEYSTVEE
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KA0 CFQSLRRKNSKASKSRTQKALILDSVNRHSYPLSSTSGNADSSAVSSQAISPYACFYGAS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CFQSLRRKNSKASKSRTQKALILDSVNRHSYPLSSTSGNADSSAVSSQAISPYACFYGAS
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KA0 AKKVKSGWLDKLSPQGKRMFQKRWVKFDGLSISYYNNEKEMYSKGIIPLSAISTVRVQGD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AKKVKSGWLDKLSPQGKRMFQKRWVKFDGLSISYYNNEKEMYSKGIIPLSAISTVRVQGD
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KA0 NKFEVVTTQRTFVFRVEKEEERNDWISILLNALKSQSLTSQSQAVVTPEKCGYLELRGYK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NKFEVVTTQRTFVFRVEKEEERNDWISILLNALKSQSLTSQSQAVVTPEKCGYLELRGYK
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KA0 AKIFTVLSGNSVWLCKNEQDFKSGLGITIIPMNVANVKQVDRTVKQSFEIITPYRSFSFT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AKIFTVLSGNSVWLCKNEQDFKSGLGITIIPMNVANVKQVDRTVKQSFEIITPYRSFSFT
              610       620       630       640       650       660

              670       680       690       700       710       720
pF1KA0 AETEKEKQDWIEAVQQSIAETLSDYEVAEKIWFNESNRSCADCKAPDPDWASINLCVVIC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AETEKEKQDWIEAVQQSIAETLSDYEVAEKIWFNESNRSCADCKAPDPDWASINLCVVIC
              670       680       690       700       710       720

              730       740       750       760       770       780
pF1KA0 KKCAGQHRSLGPKDSKVRSLKMDASIWSNELIELFIVIGNKRANDFWAGNLQKDEELHMD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KKCAGQHRSLGPKDSKVRSLKMDASIWSNELIELFIVIGNKRANDFWAGNLQKDEELHMD
              730       740       750       760       770       780

              790       800       810       820       830       840
pF1KA0 SPVEKRKNFITQKYKEGKFRKTLLASLTKEELNKALCAAVVKPDVLETMALLFSGADVMC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SPVEKRKNFITQKYKEGKFRKTLLASLTKEELNKALCAAVVKPDVLETMALLFSGADVMC
              790       800       810       820       830       840

              850       860       870       880       890       900
pF1KA0 ATGDPVHSTPYLLAKKAGQSLQMEFLYHNKFSDFPQHDIHSEGVLSQESSQSTFLCDFLY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ATGDPVHSTPYLLAKKAGQSLQMEFLYHNKFSDFPQHDIHSEGVLSQESSQSTFLCDFLY
              850       860       870       880       890       900

              910       920       930       940       950       960
pF1KA0 QAPSAASKLSSEKKLLEETNKKWCVLEGGFLSYYENDKSTTPNGTININEVICLAIHKED
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QAPSAASKLSSEKKLLEETNKKWCVLEGGFLSYYENDKSTTPNGTININEVICLAIHKED
              910       920       930       940       950       960

              970       980       990      1000      1010      1020
pF1KA0 FYLNTGPIFIFEIYLPSERVFLFGAETSQAQRKWTEAIAKHFVPLFAENLTEADYDLIGQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FYLNTGPIFIFEIYLPSERVFLFGAETSQAQRKWTEAIAKHFVPLFAENLTEADYDLIGQ
              970       980       990      1000      1010      1020

             1030      1040      1050      1060      1070      1080
pF1KA0 LFYKDCHALDQWRKGWFAMDKSSLHFCLQMQEVQGDRMHLRRLQELTISTMVQNGEKLDV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LFYKDCHALDQWRKGWFAMDKSSLHFCLQMQEVQGDRMHLRRLQELTISTMVQNGEKLDV
             1030      1040      1050      1060      1070      1080

             1090      1100      1110      1120      1130      1140
pF1KA0 LLLVEKGRTLYIHGHTKLDFTVWHTAIEKAAGTDGNALQDQQLSKNDVPIIVNSCIAFVT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LLLVEKGRTLYIHGHTKLDFTVWHTAIEKAAGTDGNALQDQQLSKNDVPIIVNSCIAFVT
             1090      1100      1110      1120      1130      1140

             1150      1160      1170      1180      1190      1200
pF1KA0 QYGLGCKYIYQKNGDPLHISELLESFKKDARSFKLRAGKHQLEDVTAVLKSFLSDIDDAL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QYGLGCKYIYQKNGDPLHISELLESFKKDARSFKLRAGKHQLEDVTAVLKSFLSDIDDAL
             1150      1160      1170      1180      1190      1200

             1210      1220      1230      1240      1250      1260
pF1KA0 LTKELYPYWISALDTQDDKERIKKYGAFIRSLPGVNRATLAAIIEHLYRVQKCSEINHMN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LTKELYPYWISALDTQDDKERIKKYGAFIRSLPGVNRATLAAIIEHLYRVQKCSEINHMN
             1210      1220      1230      1240      1250      1260

             1270      1280      1290      1300      1310      1320
pF1KA0 AHNLALVFSSCLFQTKGQTSEEVNVIEDLINNYVEIFEVKEDQVKQMDIENSFITKWKDT
       :::::::::::::::::::::::::::::::::::::::                     
XP_016 AHNLALVFSSCLFQTKGQTSEEVNVIEDLINNYVEIFEV---------------------
             1270      1280      1290                              

             1330      1340      1350      1360      1370      1380
pF1KA0 QVSQAGDLLIEVYVERKEPDCSIIIRISPVMEAEELTNDILAIKNIIPTKGDIWATFEVI
         ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 --SQAGDLLIEVYVERKEPDCSIIIRISPVMEAEELTNDILAIKNIIPTKGDIWATFEVI
      1300      1310      1320      1330      1340      1350       

             1390      1400      1410      1420      1430      1440
pF1KA0 ENEELERPLHYKENVLEQVLRWSSLAEPGSAYLVVKRFLTADTIKHCSDRSTLGSIKEGI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ENEELERPLHYKENVLEQVLRWSSLAEPGSAYLVVKRFLTADTIKHCSDRSTLGSIKEGI
      1360      1370      1380      1390      1400      1410       

             1450      1460      1470      1480      1490      1500
pF1KA0 LKIKEEPSKILSGNKFQDRYFVLRDGFLFLYKDVKSSKHDKMFSLSSMKFYRGVKKKMKP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LKIKEEPSKILSGNKFQDRYFVLRDGFLFLYKDVKSSKHDKMFSLSSMKFYRGVKKKMKP
      1420      1430      1440      1450      1460      1470       

             1510      1520      1530      1540      1550      1560
pF1KA0 PTSWGLTAYSEKHHWHLCCDSSQTQTEWMTSIFIAQHEYDIWPPAGKERKRSITKNPKIG
       ::::::::::::::::::::::.:::::::::::::::::::::::::::::::::::::
XP_016 PTSWGLTAYSEKHHWHLCCDSSRTQTEWMTSIFIAQHEYDIWPPAGKERKRSITKNPKIG
      1480      1490      1500      1510      1520      1530       

             1570      1580      1590      1600      1610      1620
pF1KA0 GLPLIPIQHEGNATLARKNIESARAELERLRLSEKCDKESVDSSLKERASMVAHCLEHKD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GLPLIPIQHEGNATLARKNIESARAELERLRLSEKCDKESVDSSLKERASMVAHCLEHKD
      1540      1550      1560      1570      1580      1590       

             1630      1640      1650      1660      1670      1680
pF1KA0 DKLRNRPRKHRSFNCLEDTEPEAPLGQPKGHKGLKTLRKTEDRNSKATLDSDHKLPSRVI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DKLRNRPRKHRSFNCLEDTEPEAPLGQPKGHKGLKTLRKTEDRNSKATLDSDHKLPSRVI
      1600      1610      1620      1630      1640      1650       

             1690      1700    
pF1KA0 EELNVVLQRSRTLPKELQDEQILK
       ::::::::::::::::::::::::
XP_016 EELNVVLQRSRTLPKELQDEQILK
      1660      1670      1680 

>>NP_056057 (OMIM: 606646) arf-GAP with Rho-GAP domain,   (1205 aa)
 initn: 2581 init1: 1026 opt: 2749  Z-score: 2197.9  bits: 419.2 E(85289): 1.1e-115
Smith-Waterman score: 2904; 41.7% identity (70.6% similar) in 1143 aa overlap (484-1591:84-1203)

           460       470       480       490       500       510   
pF1KA0 SSTSGNADSSAVSSQAISPYACFYGASAKKVKSGWLDKLSPQGKRMFQKRWVKFDGLSIS
                                     .:.:::::  :::. ..:::::..:   . 
NP_056 SSLSLSLPSTIAAPHPMDGPPGGSTPVTPVIKAGWLDKNPPQGSYIYQKRWVRLDTDHLR
            60        70        80        90       100       110   

           520       530       540       550       560       570   
pF1KA0 YYNNEKEMYSKGIIPLSAISTVRVQGDNKFEVVTTQRTFVFRVEKEEERNDWISILLNAL
       :....:. ::: .: .. :: : . ::.::::.:..:::.::.:.. ::..:.. : .:.
NP_056 YFDSNKDAYSKRFISVACISHVAAIGDQKFEVITNNRTFAFRAESDVERKEWMQALQQAM
           120       130       140       150       160       170   

           580               590       600       610       620     
pF1KA0 KSQSLTSQ-SQAVVT-------PEKCGYLELRGYKAKIFTVLSGNSVWLCKNEQDFKSGL
         :   .. :.: .        :.. : :::::.: :..... :..: : :: .... :.
NP_056 AEQRARARLSSAYLLGVPGSEQPDRAGSLELRGFKNKLYVAVVGDKVQLYKNLEEYHLGI
           180       190       200       210       220       230   

         630       640       650       660       670       680     
pF1KA0 GITIIPMNVANVKQVDRTVKQSFEIITPYRSFSFTAETEKEKQDWIEAVQQSIAETLSDY
       :::.: :.:.:::.:::   .::.. :::: :::.:..: ::..:.::.: .:::.::  
NP_056 GITFIDMSVGNVKEVDR---RSFDLTTPYRIFSFSADSELEKEQWLEAMQGAIAEALSTS
           240       250          260       270       280       290

         690       700       710       720       730       740     
pF1KA0 EVAEKIWFNESNRSCADCKAPDPDWASINLCVVICKKCAGQHRSLGPKDSKVRSLKMDAS
       ::::.::    :: :::: ::.::::::::::::::.:::.::.::   ::::::::: .
NP_056 EVAERIWAAAPNRFCADCGAPQPDWASINLCVVICKRCAGEHRGLGAGVSKVRSLKMDRK
              300       310       320       330       340       350

         750       760       770       780       790       800     
pF1KA0 IWSNELIELFIVIGNKRANDFWAGNLQKDEELHMDSPVEKRKNFITQKYKEGKFRKTLLA
       .:.. :::::. .::  .: :::.:.  .: :. .:    :.  .  ::.:::.:.    
NP_056 VWTETLIELFLQLGNGAGNRFWAANVPPSEALQPSSSPSTRRCHLEAKYREGKYRRYHPL
              360       370       380       390       400       410

         810       820       830       840       850       860     
pF1KA0 SLTKEELNKALCAAVVKPDVLETMALLFSGADVMCATGDPVHSTPYLLAKKAGQSLQMEF
         ..:::.:::::::.  :. ::.:::  :: . : .:::   ::  ::..:::.:::::
NP_056 FGNQEELDKALCAAVTTTDLAETQALLGCGAGINCFSGDPEAPTPLALAEQAGQTLQMEF
              420       430       440       450       460       470

         870       880       890          900       910       920  
pF1KA0 LYHNKFSDFPQHDIHSEGVLSQESS---QSTFLCDFLYQAPSAASKLSSEKKLLEETNKK
       : .:. .. :. :  :   : .. :    ..    :::.. ::. :: ....  :: ...
NP_056 LRNNRTTEVPRLD--SMKPLEKHYSVVLPTVSHSGFLYKTASAG-KLLQDRRAREEFSRR
              480         490       500       510        520       

            930       940       950       960       970       980  
pF1KA0 WCVLEGGFLSYYENDKSTTPNGTININEVICLAIHKEDFYLNTGPIFIFEIYLPSERVFL
       ::::  : :::.::....:::: :  .:..:::.   : .   :    ::.:  .::..:
NP_056 WCVLGDGVLSYFENERAVTPNGEIRASEIVCLAVPPPDTH---GFEHTFEVYTEGERLYL
       530       540       550       560          570       580    

            990      1000      1010      1020      1030      1040  
pF1KA0 FGAETSQAQRKWTEAIAKHFVPLFAENLTEADYDLIGQLFYKDCHALDQWRKGWFAMDKS
       :: :...  ..:.. ::: ::: .::.:   :.. .:.: ::   .:.. ..:::... :
NP_056 FGLESAEQAHEWVKCIAKAFVPPLAEDLLARDFERLGRLPYKAGLSLQRAQEGWFSLSGS
          590       600       610       620       630       640    

           1050      1060      1070      1080      1090      1100  
pF1KA0 SLHFCLQMQEVQGDRMHLRRLQELTISTMVQNGEKLDVLLLVEKGRTLYIHGHTKLDFTV
        :.  .     . . ..::.::::.:    :.  . .::.:::. :::::.:. .:::  
NP_056 ELRAVFPEGPCE-EPLQLRKLQELSI----QGDSENQVLVLVERRRTLYIQGERRLDFMG
          650        660           670       680       690         

           1110      1120      1130      1140      1150      1160  
pF1KA0 WHTAIEKAAGTDGNALQDQQLSKNDVPIIVNSCIAFVTQYGLGCKYIYQKNGDPLHISEL
       :  ::.:::.. :..:..:::. .:.:.::  :. ..:: ::  . ::.: :.  . ..:
NP_056 WLGAIQKAAASMGDTLSEQQLGDSDIPVIVYRCVDYITQCGLTSEGIYRKCGQTSKTQRL
     700       710       720       730       740       750         

           1170      1180      1190      1200      1210      1220  
pF1KA0 LESFKKDARSFKLRAGKHQLEDVTAVLKSFLSDIDDALLTKELYPYWISALDTQDDKERI
       :::...:::: .:. :.....::...:: :: :. :.:.:.     :. : . .:..:..
NP_056 LESLRQDARSVHLKEGEQHVDDVSSALKRFLRDLPDGLFTRAQRLTWLEASEIEDEEEKV
     760       770       780       790       800       810         

           1230      1240      1250      1260      1270      1280  
pF1KA0 KKYGAFIRSLPGVNRATLAAIIEHLYRVQKCSEINHMNAHNLALVFSSCLFQTKGQTSEE
       ..:  ..  :: :::::. :.: ::: ::  :. :.::.::::.::.  :::: ::  . 
NP_056 SRYRELLVRLPPVNRATVKALISHLYCVQCFSDTNQMNVHNLAIVFGPTLFQTDGQDYKA
     820       830       840       850       860       870         

           1290      1300      1310          1320      1330        
pF1KA0 VNVIEDLINNYVEIFEVKEDQVKQMDIENSFITKWK----DTQVSQAGDLLIEVYVERKE
         :.:::::.:: .: : :......  : . :.: .     . ...:::..  ::.:.:.
NP_056 GRVVEDLINHYVVVFSVDEEELRKQREEITAIVKMRVAGTASGTQHAGDFICTVYLEEKK
     880       890       900       910       920       930         

     1340      1350      1360      1370      1380      1390        
pF1KA0 PDCSIIIRISPVMEAEELTNDILAIKNIIPTKGDIWATFEVIENEELERPLHYKENVLEQ
        .    :..   : ::::: .::  .:.   . : :. ::: : :: :::::. :.::  
NP_056 AETEQHIKVPASMTAEELTLEILDRRNVGIREKDYWTCFEVNEREEAERPLHFAEKVLP-
     940       950       960       970       980       990         

     1400      1410      1420      1430      1440      1450        
pF1KA0 VLRWSSLAEPGSAYLVVKRFLTADTIKHCSDRSTLGSIKEGILKIKEEPSKI---LSGNK
       .:.  .:.   ...::::.  . ...      : .:. :.:..:..:. : .   : .. 
NP_056 ILH--GLGT--DSHLVVKKHQAMEAML-LYLASRVGDTKHGMMKFREDRSLLGLGLPSGG
     1000          1010      1020       1030      1040      1050   

        1460      1470                 1480      1490      1500    
pF1KA0 FQDRYFVLRDGFLFLYKDVKSSK---------H--DKMFSLSSMKFYRGVKKKMKPPTSW
       :.::::.: .. : :::.:.:..         :  .: . ..:.: : :::::..::: :
NP_056 FHDRYFILNSSCLRLYKEVRSQRPWSGAPETSHRPEKEWPIKSLKVYLGVKKKLRPPTCW
          1060      1070      1080      1090      1100      1110   

           1510         1520      1530      1540      1550         
pF1KA0 GLTAY--SEKH---HWHLCCDSSQTQTEWMTSIFIAQHEYDIWPPAGKERKRSITKNPKI
       :.:.   .:::   .:.::::...   ::.......::.  .::   .. .:.. .  ..
NP_056 GFTVVHETEKHEKQQWYLCCDTQMELREWFATFLFVQHDGLVWPSEPSRVSRAVPEV-RL
          1120      1130      1140      1150      1160      1170   

    1560      1570      1580       1590      1600      1610        
pF1KA0 GGLPLIPIQHEGNATLARKNIESARAE-LERLRLSEKCDKESVDSSLKERASMVAHCLEH
       :.. :::..  :. .  :... .  :. :  ::                           
NP_056 GSVSLIPLR--GSENEMRRSVAAFTADPLSLLRNV                         
           1180        1190      1200                              

     1620      1630      1640      1650      1660      1670        
pF1KA0 KDDKLRNRPRKHRSFNCLEDTEPEAPLGQPKGHKGLKTLRKTEDRNSKATLDSDHKLPSR

>>NP_001035207 (OMIM: 606646) arf-GAP with Rho-GAP domai  (1450 aa)
 initn: 2682 init1: 1026 opt: 2749  Z-score: 2196.9  bits: 419.3 E(85289): 1.2e-115
Smith-Waterman score: 2904; 41.7% identity (70.6% similar) in 1143 aa overlap (484-1591:329-1448)

           460       470       480       490       500       510   
pF1KA0 SSTSGNADSSAVSSQAISPYACFYGASAKKVKSGWLDKLSPQGKRMFQKRWVKFDGLSIS
                                     .:.:::::  :::. ..:::::..:   . 
NP_001 SSLSLSLPSTIAAPHPMDGPPGGSTPVTPVIKAGWLDKNPPQGSYIYQKRWVRLDTDHLR
      300       310       320       330       340       350        

           520       530       540       550       560       570   
pF1KA0 YYNNEKEMYSKGIIPLSAISTVRVQGDNKFEVVTTQRTFVFRVEKEEERNDWISILLNAL
       :....:. ::: .: .. :: : . ::.::::.:..:::.::.:.. ::..:.. : .:.
NP_001 YFDSNKDAYSKRFISVACISHVAAIGDQKFEVITNNRTFAFRAESDVERKEWMQALQQAM
      360       370       380       390       400       410        

           580               590       600       610       620     
pF1KA0 KSQSLTSQ-SQAVVT-------PEKCGYLELRGYKAKIFTVLSGNSVWLCKNEQDFKSGL
         :   .. :.: .        :.. : :::::.: :..... :..: : :: .... :.
NP_001 AEQRARARLSSAYLLGVPGSEQPDRAGSLELRGFKNKLYVAVVGDKVQLYKNLEEYHLGI
      420       430       440       450       460       470        

         630       640       650       660       670       680     
pF1KA0 GITIIPMNVANVKQVDRTVKQSFEIITPYRSFSFTAETEKEKQDWIEAVQQSIAETLSDY
       :::.: :.:.:::.:::   .::.. :::: :::.:..: ::..:.::.: .:::.::  
NP_001 GITFIDMSVGNVKEVDR---RSFDLTTPYRIFSFSADSELEKEQWLEAMQGAIAEALSTS
      480       490          500       510       520       530     

         690       700       710       720       730       740     
pF1KA0 EVAEKIWFNESNRSCADCKAPDPDWASINLCVVICKKCAGQHRSLGPKDSKVRSLKMDAS
       ::::.::    :: :::: ::.::::::::::::::.:::.::.::   ::::::::: .
NP_001 EVAERIWAAAPNRFCADCGAPQPDWASINLCVVICKRCAGEHRGLGAGVSKVRSLKMDRK
         540       550       560       570       580       590     

         750       760       770       780       790       800     
pF1KA0 IWSNELIELFIVIGNKRANDFWAGNLQKDEELHMDSPVEKRKNFITQKYKEGKFRKTLLA
       .:.. :::::. .::  .: :::.:.  .: :. .:    :.  .  ::.:::.:.    
NP_001 VWTETLIELFLQLGNGAGNRFWAANVPPSEALQPSSSPSTRRCHLEAKYREGKYRRYHPL
         600       610       620       630       640       650     

         810       820       830       840       850       860     
pF1KA0 SLTKEELNKALCAAVVKPDVLETMALLFSGADVMCATGDPVHSTPYLLAKKAGQSLQMEF
         ..:::.:::::::.  :. ::.:::  :: . : .:::   ::  ::..:::.:::::
NP_001 FGNQEELDKALCAAVTTTDLAETQALLGCGAGINCFSGDPEAPTPLALAEQAGQTLQMEF
         660       670       680       690       700       710     

         870       880       890          900       910       920  
pF1KA0 LYHNKFSDFPQHDIHSEGVLSQESS---QSTFLCDFLYQAPSAASKLSSEKKLLEETNKK
       : .:. .. :. :  :   : .. :    ..    :::.. ::. :: ....  :: ...
NP_001 LRNNRTTEVPRLD--SMKPLEKHYSVVLPTVSHSGFLYKTASAG-KLLQDRRAREEFSRR
         720         730       740       750        760       770  

            930       940       950       960       970       980  
pF1KA0 WCVLEGGFLSYYENDKSTTPNGTININEVICLAIHKEDFYLNTGPIFIFEIYLPSERVFL
       ::::  : :::.::....:::: :  .:..:::.   : .   :    ::.:  .::..:
NP_001 WCVLGDGVLSYFENERAVTPNGEIRASEIVCLAVPPPDTH---GFEHTFEVYTEGERLYL
            780       790       800       810          820         

            990      1000      1010      1020      1030      1040  
pF1KA0 FGAETSQAQRKWTEAIAKHFVPLFAENLTEADYDLIGQLFYKDCHALDQWRKGWFAMDKS
       :: :...  ..:.. ::: ::: .::.:   :.. .:.: ::   .:.. ..:::... :
NP_001 FGLESAEQAHEWVKCIAKAFVPPLAEDLLARDFERLGRLPYKAGLSLQRAQEGWFSLSGS
     830       840       850       860       870       880         

           1050      1060      1070      1080      1090      1100  
pF1KA0 SLHFCLQMQEVQGDRMHLRRLQELTISTMVQNGEKLDVLLLVEKGRTLYIHGHTKLDFTV
        :.  .     . . ..::.::::.:    :.  . .::.:::. :::::.:. .:::  
NP_001 ELRAVFPEGPCE-EPLQLRKLQELSI----QGDSENQVLVLVERRRTLYIQGERRLDFMG
     890       900        910           920       930       940    

           1110      1120      1130      1140      1150      1160  
pF1KA0 WHTAIEKAAGTDGNALQDQQLSKNDVPIIVNSCIAFVTQYGLGCKYIYQKNGDPLHISEL
       :  ::.:::.. :..:..:::. .:.:.::  :. ..:: ::  . ::.: :.  . ..:
NP_001 WLGAIQKAAASMGDTLSEQQLGDSDIPVIVYRCVDYITQCGLTSEGIYRKCGQTSKTQRL
          950       960       970       980       990      1000    

           1170      1180      1190      1200      1210      1220  
pF1KA0 LESFKKDARSFKLRAGKHQLEDVTAVLKSFLSDIDDALLTKELYPYWISALDTQDDKERI
       :::...:::: .:. :.....::...:: :: :. :.:.:.     :. : . .:..:..
NP_001 LESLRQDARSVHLKEGEQHVDDVSSALKRFLRDLPDGLFTRAQRLTWLEASEIEDEEEKV
         1010      1020      1030      1040      1050      1060    

           1230      1240      1250      1260      1270      1280  
pF1KA0 KKYGAFIRSLPGVNRATLAAIIEHLYRVQKCSEINHMNAHNLALVFSSCLFQTKGQTSEE
       ..:  ..  :: :::::. :.: ::: ::  :. :.::.::::.::.  :::: ::  . 
NP_001 SRYRELLVRLPPVNRATVKALISHLYCVQCFSDTNQMNVHNLAIVFGPTLFQTDGQDYKA
         1070      1080      1090      1100      1110      1120    

           1290      1300      1310          1320      1330        
pF1KA0 VNVIEDLINNYVEIFEVKEDQVKQMDIENSFITKWK----DTQVSQAGDLLIEVYVERKE
         :.:::::.:: .: : :......  : . :.: .     . ...:::..  ::.:.:.
NP_001 GRVVEDLINHYVVVFSVDEEELRKQREEITAIVKMRVAGTASGTQHAGDFICTVYLEEKK
         1130      1140      1150      1160      1170      1180    

     1340      1350      1360      1370      1380      1390        
pF1KA0 PDCSIIIRISPVMEAEELTNDILAIKNIIPTKGDIWATFEVIENEELERPLHYKENVLEQ
        .    :..   : ::::: .::  .:.   . : :. ::: : :: :::::. :.::  
NP_001 AETEQHIKVPASMTAEELTLEILDRRNVGIREKDYWTCFEVNEREEAERPLHFAEKVLP-
         1190      1200      1210      1220      1230      1240    

     1400      1410      1420      1430      1440      1450        
pF1KA0 VLRWSSLAEPGSAYLVVKRFLTADTIKHCSDRSTLGSIKEGILKIKEEPSKI---LSGNK
       .:.  .:.   ...::::.  . ...      : .:. :.:..:..:. : .   : .. 
NP_001 ILH--GLGT--DSHLVVKKHQAMEAML-LYLASRVGDTKHGMMKFREDRSLLGLGLPSGG
            1250        1260       1270      1280      1290        

        1460      1470                 1480      1490      1500    
pF1KA0 FQDRYFVLRDGFLFLYKDVKSSK---------H--DKMFSLSSMKFYRGVKKKMKPPTSW
       :.::::.: .. : :::.:.:..         :  .: . ..:.: : :::::..::: :
NP_001 FHDRYFILNSSCLRLYKEVRSQRPWSGAPETSHRPEKEWPIKSLKVYLGVKKKLRPPTCW
     1300      1310      1320      1330      1340      1350        

           1510         1520      1530      1540      1550         
pF1KA0 GLTAY--SEKH---HWHLCCDSSQTQTEWMTSIFIAQHEYDIWPPAGKERKRSITKNPKI
       :.:.   .:::   .:.::::...   ::.......::.  .::   .. .:.. .  ..
NP_001 GFTVVHETEKHEKQQWYLCCDTQMELREWFATFLFVQHDGLVWPSEPSRVSRAVPEV-RL
     1360      1370      1380      1390      1400      1410        

    1560      1570      1580       1590      1600      1610        
pF1KA0 GGLPLIPIQHEGNATLARKNIESARAE-LERLRLSEKCDKESVDSSLKERASMVAHCLEH
       :.. :::..  :. .  :... .  :. :  ::                           
NP_001 GSVSLIPLR--GSENEMRRSVAAFTADPLSLLRNV                         
      1420        1430      1440      1450                         

     1620      1630      1640      1650      1660      1670        
pF1KA0 KDDKLRNRPRKHRSFNCLEDTEPEAPLGQPKGHKGLKTLRKTEDRNSKATLDSDHKLPSR

>>NP_001128662 (OMIM: 606646) arf-GAP with Rho-GAP domai  (1133 aa)
 initn: 2218 init1: 701 opt: 1831  Z-score: 1467.6  bits: 284.0 E(85289): 5.2e-75
Smith-Waterman score: 2663; 40.0% identity (67.7% similar) in 1132 aa overlap (484-1591:84-1131)

           460       470       480       490       500       510   
pF1KA0 SSTSGNADSSAVSSQAISPYACFYGASAKKVKSGWLDKLSPQGKRMFQKRWVKFDGLSIS
                                     .:.:::::  :::. ..:::::..:   . 
NP_001 SSLSLSLPSTIAAPHPMDGPPGGSTPVTPVIKAGWLDKNPPQGSYIYQKRWVRLDTDHLR
            60        70        80        90       100       110   

           520       530       540       550       560       570   
pF1KA0 YYNNEKEMYSKGIIPLSAISTVRVQGDNKFEVVTTQRTFVFRVEKEEERNDWISILLNAL
       :....:. ::: .: .. :: : . ::.::::.:..:::.::.:.. ::..:.. : .:.
NP_001 YFDSNKDAYSKRFISVACISHVAAIGDQKFEVITNNRTFAFRAESDVERKEWMQALQQAM
           120       130       140       150       160       170   

           580               590       600       610       620     
pF1KA0 KSQSLTSQ-SQAVVT-------PEKCGYLELRGYKAKIFTVLSGNSVWLCKNEQDFKSGL
         :   .. :.: .        :.. : :::::.: :..... :..: : :: .... :.
NP_001 AEQRARARLSSAYLLGVPGSEQPDRAGSLELRGFKNKLYVAVVGDKVQLYKNLEEYHLGI
           180       190       200       210       220       230   

         630       640       650       660       670       680     
pF1KA0 GITIIPMNVANVKQVDRTVKQSFEIITPYRSFSFTAETEKEKQDWIEAVQQSIAETLSDY
       :::.: :.:.:::.:::   .::.. :::: :::.:..: ::..:.::.: .:::.::  
NP_001 GITFIDMSVGNVKEVDR---RSFDLTTPYRIFSFSADSELEKEQWLEAMQGAIAEALSTS
           240       250          260       270       280       290

         690       700       710       720       730       740     
pF1KA0 EVAEKIWFNESNRSCADCKAPDPDWASINLCVVICKKCAGQHRSLGPKDSKVRSLKMDAS
       ::::.::    :: :::: ::.::::::::::::::.:::.::.::   ::::::::: .
NP_001 EVAERIWAAAPNRFCADCGAPQPDWASINLCVVICKRCAGEHRGLGAGVSKVRSLKMDRK
              300       310       320       330       340       350

         750       760       770       780       790       800     
pF1KA0 IWSNELIELFIVIGNKRANDFWAGNLQKDEELHMDSPVEKRKNFITQKYKEGKFRKTLLA
       .:.. :::                                                    
NP_001 VWTETLIE----------------------------------------------------
                                                                   

         810       820       830       840       850       860     
pF1KA0 SLTKEELNKALCAAVVKPDVLETMALLFSGADVMCATGDPVHSTPYLLAKKAGQSLQMEF
                ::::::.  :. ::.:::  :: . : .:::   ::  ::..:::.:::::
NP_001 ---------ALCAAVTTTDLAETQALLGCGAGINCFSGDPEAPTPLALAEQAGQTLQMEF
               360       370       380       390       400         

         870       880       890          900       910       920  
pF1KA0 LYHNKFSDFPQHDIHSEGVLSQESS---QSTFLCDFLYQAPSAASKLSSEKKLLEETNKK
       : .:. .. :. :  :   : .. :    ..    :::.. ::. :: ....  :: ...
NP_001 LRNNRTTEVPRLD--SMKPLEKHYSVVLPTVSHSGFLYKTASAG-KLLQDRRAREEFSRR
     410       420         430       440       450        460      

            930       940       950       960       970       980  
pF1KA0 WCVLEGGFLSYYENDKSTTPNGTININEVICLAIHKEDFYLNTGPIFIFEIYLPSERVFL
       ::::  : :::.::....:::: :  .:..:::.   : .   :    ::.:  .::..:
NP_001 WCVLGDGVLSYFENERAVTPNGEIRASEIVCLAVPPPDTH---GFEHTFEVYTEGERLYL
        470       480       490       500          510       520   

            990      1000      1010      1020      1030      1040  
pF1KA0 FGAETSQAQRKWTEAIAKHFVPLFAENLTEADYDLIGQLFYKDCHALDQWRKGWFAMDKS
       :: :...  ..:.. ::: ::: .::.:   :.. .:.: ::   .:.. ..:::... :
NP_001 FGLESAEQAHEWVKCIAKAFVPPLAEDLLARDFERLGRLPYKAGLSLQRAQEGWFSLSGS
           530       540       550       560       570       580   

           1050      1060      1070      1080      1090      1100  
pF1KA0 SLHFCLQMQEVQGDRMHLRRLQELTISTMVQNGEKLDVLLLVEKGRTLYIHGHTKLDFTV
        :.  .     . . ..::.::::.:    :.  . .::.:::. :::::.:. .:::  
NP_001 ELRAVFPEGPCE-EPLQLRKLQELSI----QGDSENQVLVLVERRRTLYIQGERRLDFMG
           590        600           610       620       630        

           1110      1120      1130      1140      1150      1160  
pF1KA0 WHTAIEKAAGTDGNALQDQQLSKNDVPIIVNSCIAFVTQYGLGCKYIYQKNGDPLHISEL
       :  ::.:::.. :..:..:::. .:.:.::  :. ..:: ::  . ::.: :.  . ..:
NP_001 WLGAIQKAAASMGDTLSEQQLGDSDIPVIVYRCVDYITQCGLTSEGIYRKCGQTSKTQRL
      640       650       660       670       680       690        

           1170      1180      1190      1200      1210      1220  
pF1KA0 LESFKKDARSFKLRAGKHQLEDVTAVLKSFLSDIDDALLTKELYPYWISALDTQDDKERI
       :::...:::: .:. :.....::...:: :: :. :.:.:.     :. : . .:..:..
NP_001 LESLRQDARSVHLKEGEQHVDDVSSALKRFLRDLPDGLFTRAQRLTWLEASEIEDEEEKV
      700       710       720       730       740       750        

           1230      1240      1250      1260      1270      1280  
pF1KA0 KKYGAFIRSLPGVNRATLAAIIEHLYRVQKCSEINHMNAHNLALVFSSCLFQTKGQTSEE
       ..:  ..  :: :::::. :.: ::: ::  :. :.::.::::.::.  :::: ::  . 
NP_001 SRYRELLVRLPPVNRATVKALISHLYCVQCFSDTNQMNVHNLAIVFGPTLFQTDGQDYKA
      760       770       780       790       800       810        

           1290      1300      1310          1320      1330        
pF1KA0 VNVIEDLINNYVEIFEVKEDQVKQMDIENSFITKWK----DTQVSQAGDLLIEVYVERKE
         :.:::::.:: .: : :......  : . :.: .     . ...:::..  ::.:.:.
NP_001 GRVVEDLINHYVVVFSVDEEELRKQREEITAIVKMRVAGTASGTQHAGDFICTVYLEEKK
      820       830       840       850       860       870        

     1340      1350      1360      1370      1380      1390        
pF1KA0 PDCSIIIRISPVMEAEELTNDILAIKNIIPTKGDIWATFEVIENEELERPLHYKENVLEQ
        .    :..   : ::::: .::  .:.   . : :. ::: : :: :::::. :.::  
NP_001 AETEQHIKVPASMTAEELTLEILDRRNVGIREKDYWTCFEVNEREEAERPLHFAEKVLP-
      880       890       900       910       920       930        

     1400      1410      1420      1430      1440      1450        
pF1KA0 VLRWSSLAEPGSAYLVVKRFLTADTIKHCSDRSTLGSIKEGILKIKEEPSKI---LSGNK
       .:.  .:.   ...::::.  . ...      : .:. :.:..:..:. : .   : .. 
NP_001 ILH--GLGT--DSHLVVKKHQAMEAML-LYLASRVGDTKHGMMKFREDRSLLGLGLPSGG
       940           950       960        970       980       990  

        1460      1470      1480      1490      1500        1510   
pF1KA0 FQDRYFVLRDGFLFLYKDVKSSKHDKMFSLSSMKFYRGVKKKMKPPTSWGLTAY--SEKH
       :.::::.: .. : :::.:.: . .: . ..:.: : :::::..::: ::.:.   .:::
NP_001 FHDRYFILNSSCLRLYKEVRSHRPEKEWPIKSLKVYLGVKKKLRPPTCWGFTVVHETEKH
           1000      1010      1020      1030      1040      1050  

             1520      1530      1540      1550      1560      1570
pF1KA0 ---HWHLCCDSSQTQTEWMTSIFIAQHEYDIWPPAGKERKRSITKNPKIGGLPLIPIQHE
          .:.::::...   ::.......::.  .::   .. .:.. .  ..:.. :::..  
NP_001 EKQQWYLCCDTQMELREWFATFLFVQHDGLVWPSEPSRVSRAVPEV-RLGSVSLIPLR--
           1060      1070      1080      1090       1100           

             1580       1590      1600      1610      1620         
pF1KA0 GNATLARKNIESARAE-LERLRLSEKCDKESVDSSLKERASMVAHCLEHKDDKLRNRPRK
       :. .  :... .  :. :  ::                                      
NP_001 GSENEMRRSVAAFTADPLSLLRNV                                    
    1110      1120      1130                                       

>>XP_011535979 (OMIM: 606647) PREDICTED: arf-GAP with Rh  (1349 aa)
 initn: 2707 init1: 1024 opt: 1700  Z-score: 1362.4  bits: 264.8 E(85289): 3.8e-69
Smith-Waterman score: 2864; 40.5% identity (67.0% similar) in 1226 aa overlap (452-1649:58-1248)

             430       440       450         460       470         
pF1KA0 FQSLRRKNSKASKSRTQKALILDSVNRHSYPLSST--SGNADSSAVSSQAISPYACFYGA
                                     : .::  : . ..  .:.. ::::: :  .
XP_011 RGVCQGRAEHRLSRQDLEAREDAGYASLELPGDSTLLSPTLETEETSDDLISPYASFSFT
        30        40        50        60        70        80       

     480         490       500       510       520       530       
pF1KA0 SAK--KVKSGWLDKLSPQGKRMFQKRWVKFDGLSISYYNNEKEMYSKGIIPLSAISTVRV
       . .   . :::::::::::. .::.:.:.:.: :. :....:. . ::.:::.::  .: 
XP_011 ADRLTPLLSGWLDKLSPQGNYVFQRRFVQFNGRSLMYFGSDKDPFPKGVIPLTAIEMTRS
        90       100       110       120       130       140       

       540       550       560       570       580         590     
pF1KA0 QGDNKFEVVTTQRTFVFRVEKEEERNDWISILLNALKSQSLTSQSQAVVTPE--KCGYLE
       . ::::.:.: ::.::::.:.: .:. : : : . :: : : .. .    :.  . :.::
XP_011 SKDNKFQVITGQRVFVFRTESEAQRDMWCSTLQSCLKEQRLLGHPRPPQPPRPLRTGMLE
       150       160       170       180       190       200       

         600       610       620       630       640       650     
pF1KA0 LRGYKAKIFTVLSGNSVWLCKNEQDFKSGLGITIIPMNVANVKQVDRTVKQSFEIITPYR
       :::.:::.:..:: . . : :.:: :. :.:: .: ..  .:..   : ..::...::.:
XP_011 LRGHKAKVFAALSPGELALYKSEQAFSLGIGICFIELQGCSVRE---TKSRSFDLLTPHR
       210       220       230       240       250          260    

         660       670       680       690       700       710     
pF1KA0 SFSFTAETEKEKQDWIEAVQQSIAETLSDYEVAEKIWFNESNRSCADCKAPDPDWASINL
        ::::::.   .:.:  :.:....::::::::::::: :..::.:::: .  ::::..::
XP_011 CFSFTAESGGARQSWAAALQEAVTETLSDYEVAEKIWSNRANRQCADCGSSRPDWAAVNL
          270       280       290       300       310       320    

         720       730       740       750       760       770     
pF1KA0 CVVICKKCAGQHRSLGPKDSKVRSLKMDASIWSNELIELFIVIGNKRANDFWAGNLQKDE
        :::::.::::::.::   :::.:::.:.:.::::...::::.:: ::: ::::.:   :
XP_011 GVVICKQCAGQHRALGSGISKVQSLKLDTSVWSNEIVQLFIVLGNDRANRFWAGTLPPGE
          330       340       350       360       370       380    

         780       790       800       810       820       830     
pF1KA0 ELHMDSPVEKRKNFITQKYKEGKFRKTLLASLTKEELNKALCAAVVKPDVLETMALL---
        :: :.    : .::..::. : :::       . .: .::::::..:..:..:. :   
XP_011 GLHPDATPGPRGEFISRKYRLGLFRKPHPQYPDHSQLLQALCAAVARPNLLKNMTQLLCV
          390       400       410       420       430       440    

              840       850       860       870       880       890
pF1KA0 --FSGADVMCATGDPVHSTPYLLAKKAGQSLQMEFLYHNKFSDFPQHDIHSEGVLSQESS
         : : .     . :  : : ::                  :: :     : :: ..   
XP_011 EAFEGEEPWFPPA-PDGSCPGLLP-----------------SD-P-----SPGVYNEVVV
          450        460                         470            480

              900        910       920       930       940         
pF1KA0 QSTFLCDFLYQAP-SAASKLSSEKKLLEETNKKWCVLEGGFLSYYENDKSTTPNGTININ
       ..:.   ::: .: :  .  :  ..  .   . :::: :. : .. ...:  : . :. .
XP_011 RATY-SGFLYCSPVSNKAGPSPPRRGRDAPPRLWCVL-GAALEMFASENSPEPLSLIQPQ
               490       500       510        520       530        

     950       960       970       980       990      1000         
pF1KA0 EVICLAIHKEDFYLNTGPIFIFEIYLPSERVFLFGAETSQAQRKWTEAIAKHFVPLFAEN
       ...::..       .    : ::. : . :.  ::.. ... . :: :..: : ::  ..
XP_011 DIVCLGVSPPPTDPGDRFPFSFELILAGGRIQHFGTDGADSLEAWTSAVGKWFSPLSCHQ
      540       550       560       570       580       590        

    1010      1020          1030      1040      1050         1060  
pF1KA0 LTEADYDLIGQLFYKD-CH---ALDQWRKGWFAMDKSSLHFCLQM---QEVQGDRMHLRR
       :       .:.:. ..  :   :   : .:.  .  . : .:        .  : .::::
XP_011 LLGPGLLRLGRLWLRSPSHTAPAPGLWLSGFGLLRGDHLFLCSAPGPGPPAPEDMVHLRR
      600       610       620       630       640       650        

           1070      1080      1090      1100      1110      1120  
pF1KA0 LQELTISTMVQNGEKLDVLLLVEKGRTLYIHGHTKLDFTVWHTAIEKAAGTDGNALQDQQ
       :::... . ... .: . :.::: :::::..:. .::::.:..::  :::  :..::.::
XP_011 LQEISVVSAADTPDKKEHLVLVETGRTLYLQGEGRLDFTAWNAAIGGAAGGGGTGLQEQQ
      660       670       680       690       700       710        

           1130      1140      1150      1160      1170      1180  
pF1KA0 LSKNDVPIIVNSCIAFVTQYGLGCKYIYQKNGDPLHISELLESFKKDARSFKLRAGKHQL
       .:..:.::::..::.::::.::  . .:.:.:   .  .::  :..:::: ::: :.: .
XP_011 MSRGDIPIIVDACISFVTQHGLRLEGVYRKGGARARSLRLLAEFRRDARSVKLRPGEHFV
      720       730       740       750       760       770        

           1190      1200      1210      1220      1230      1240  
pF1KA0 EDVTAVLKSFLSDIDDALLTKELYPYWISALDTQDDKERIKKYGAFIRSLPGVNRATLAA
       :::: .:: :. ..:: . . .: : :  : .  . ..:..::   :  :: ::: :::.
XP_011 EDVTDTLKRFFRELDDPVTSARLLPRWREAAELPQKNQRLEKYKDVIGCLPRVNRRTLAT
      780       790       800       810       820       830        

           1250      1260      1270      1280      1290      1300  
pF1KA0 IIEHLYRVQKCSEINHMNAHNLALVFSSCLFQTKGQTSEEVNVIEDLINNYVEIFEVKED
       .: ::::::::. .:.: ..::::.:.  .::: :.  .:: :...::..:. .:..  :
XP_011 LIGHLYRVQKCAALNQMCTRNLALLFAPSVFQTDGRGEHEVRVLQELIDGYISVFDIDSD
      840       850       860       870       880       890        

           1310      1320      1330      1340      1350      1360  
pF1KA0 QVKQMDIENSFITKWKDTQVSQAGDLLIEVYVERKEPDCSIIIRISPVMEAEELTNDILA
       :: :.:.: :.:: :::.:.::::::..:::.:.. ::  . ...::.. ::::::..: 
XP_011 QVAQIDLEVSLITTWKDVQLSQAGDLIMEVYIEQQLPDNCVTLKVSPTLTAEELTNQVLE
      900       910       920       930       940       950        

           1370      1380      1390      1400      1410      1420  
pF1KA0 IKNIIPTKGDIWATFEVIENEELERPLHYKENVLEQVLRWSSLAEPGSAYLVVKRFLTAD
       ...   .  :.:.:::. :. ::::::: ::.::::.:.: .: :: :: :..:.   :.
XP_011 MRGTA-AGMDLWVTFEIREHGELERPLHPKEKVLEQALQWCQLPEPCSASLLLKKVPLAQ
      960        970       980       990      1000      1010       

           1430       1440      1450      1460      1470      1480 
pF1KA0 TIKHCSDRSTLG-SIKEGILKIKEEPSKILSGNKFQDRYFVLRDGFLFLYKDVKSSKHDK
       .   :   .    : . :.:. .::: ..: :..::.:.:.::   :.: :. :::: ..
XP_011 A--GCLFTGIRRESPRVGLLRCREEPPRLL-GSRFQERFFLLRGRCLLLLKEKKSSKPER
        1020      1030      1040       1050      1060      1070    

            1490      1500      1510      1520      1530      1540 
pF1KA0 MFSLSSMKFYRGVKKKMKPPTSWGLTAYSEKHHWHLCCDSSQTQTEWMTSIFIAQHEYDI
        . : . : : :..::.:::: ::.:   :: : .: : . . . .: :::. :::. : 
XP_011 EWPLEGAKVYLGIRKKLKPPTPWGFTLILEKMHLYLSCTDEDEMWDWTTSILKAQHD-DQ
         1080      1090      1100      1110      1120      1130    

            1550      1560       1570      1580      1590      1600
pF1KA0 WPPAGKERKRSITKNPKIGGLPLIPIQ-HEGNATLARKNIESARAELERLRLSEKCDKES
        : . .... :     :.: .::.::.  ...:::   : .. :   .:  ::     .:
XP_011 QPVVLRRHSSSDLARQKFGTMPLLPIRGDDSGATLLSAN-QTLRRLHNRRTLSMFFPMKS
          1140      1150      1160      1170       1180      1190  

             1610       1620          1630        1640      1650   
pF1KA0 VDSSLKERASMVAHCLEHK-DDKLRNRPR----KHRSFNCLED--TEPEAPLGQPKGHKG
        ..:..:.  .     :.   ...   :.       ::.  ..  ..:: :: . :    
XP_011 SQGSVEEQEELEEPVYEEPVYEEVGAFPELIQDTSTSFSTTREWTVKPENPLTSQKSLDQ
           1200      1210      1220      1230      1240      1250  

          1660      1670      1680      1690      1700             
pF1KA0 LKTLRKTEDRNSKATLDSDHKLPSRVIEELNVVLQRSRTLPKELQDEQILK         
                                                                   
XP_011 PFLSKSSTLGQEERPPEPPPGPPSKSSPQARGSLEEQLLQELSSLILRKGETTAGLGSPS
           1260      1270      1280      1290      1300      1310  




1704 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Thu Nov  3 09:46:43 2016 done: Thu Nov  3 09:46:46 2016
 Total Scan time: 16.830 Total Display time:  1.190

Function used was FASTA [36.3.4 Apr, 2011]
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