Result of FASTA (ccds) for pF1KA0551
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KA0551, 1360 aa
  1>>>pF1KA0551 1360 - 1360 aa - 1360 aa
Library: human.CCDS.faa
  18511270 residues in 32554 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 16.9744+/-0.00146; mu= -30.5451+/- 0.088
 mean_var=704.0381+/-149.489, 0's: 0 Z-trim(113.5): 527  B-trim: 103 in 1/53
 Lambda= 0.048337
 statistics sampled from 13579 (14138) to 13579 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.728), E-opt: 0.2 (0.434), width:  16
 Scan time:  6.530

The best scores are:                                      opt bits E(32554)
CCDS46956.1 TNIK gene_id:23043|Hs108|chr3          (1360) 9018 645.3 3.3e-184
CCDS54679.1 TNIK gene_id:23043|Hs108|chr3          (1352) 8943 640.1 1.2e-182
CCDS54676.1 TNIK gene_id:23043|Hs108|chr3          (1331) 6028 436.8 1.9e-121
CCDS54675.1 TNIK gene_id:23043|Hs108|chr3          (1323) 5919 429.2 3.7e-119
CCDS54678.1 TNIK gene_id:23043|Hs108|chr3          (1305) 5232 381.3 9.6e-105
CCDS54674.1 TNIK gene_id:23043|Hs108|chr3          (1276) 5217 380.2 1.9e-104
CCDS54673.1 TNIK gene_id:23043|Hs108|chr3          (1268) 5122 373.6 1.9e-102
CCDS54677.1 TNIK gene_id:23043|Hs108|chr3          (1297) 5092 371.5 8.3e-102
CCDS74546.1 MAP4K4 gene_id:9448|Hs108|chr2         (1273) 2908 219.2 5.8e-56
CCDS82487.1 MAP4K4 gene_id:9448|Hs108|chr2         (1165) 2791 211.0 1.5e-53
CCDS56130.1 MAP4K4 gene_id:9448|Hs108|chr2         (1239) 2758 208.7 7.9e-53
CCDS45588.1 MINK1 gene_id:50488|Hs108|chr17        (1332) 2529 192.8 5.4e-48
CCDS45590.1 MINK1 gene_id:50488|Hs108|chr17        (1312) 2395 183.5 3.5e-45
CCDS45589.1 MINK1 gene_id:50488|Hs108|chr17        (1303) 2344 179.9 4.1e-44
CCDS65305.1 NRK gene_id:203447|Hs108|chrX          (1582) 1239 102.9 7.5e-21
CCDS7148.1 MYO3A gene_id:53904|Hs108|chr10         (1616) 1023 87.8 2.6e-16
CCDS46446.1 MYO3B gene_id:140469|Hs108|chr2        (1314)  999 86.1   7e-16
CCDS42773.1 MYO3B gene_id:140469|Hs108|chr2        (1341)  999 86.1 7.1e-16
CCDS58707.1 MAP4K3 gene_id:8491|Hs108|chr2         ( 873)  905 79.4 4.7e-14
CCDS1803.1 MAP4K3 gene_id:8491|Hs108|chr2          ( 894)  903 79.3 5.3e-14
CCDS42564.1 MAP4K1 gene_id:11184|Hs108|chr19       ( 821)  838 74.8 1.1e-12
CCDS59385.1 MAP4K1 gene_id:11184|Hs108|chr19       ( 833)  838 74.8 1.2e-12
CCDS2549.1 STK25 gene_id:10494|Hs108|chr2          ( 426)  823 73.5 1.4e-12
CCDS81582.1 MAP4K2 gene_id:5871|Hs108|chr11        ( 812)  832 74.3 1.5e-12
CCDS8082.1 MAP4K2 gene_id:5871|Hs108|chr11         ( 820)  832 74.3 1.5e-12
CCDS14631.1 STK26 gene_id:51765|Hs108|chrX         ( 416)  818 73.2 1.7e-12
CCDS76334.1 SLK gene_id:9748|Hs108|chr10           (1204)  823 73.8 3.2e-12
CCDS7553.1 SLK gene_id:9748|Hs108|chr10            (1235)  823 73.8 3.3e-12
CCDS13341.1 STK4 gene_id:6789|Hs108|chr20          ( 487)  799 71.9 4.9e-12
CCDS32001.1 STK24 gene_id:8428|Hs108|chr13         ( 431)  791 71.3 6.5e-12
CCDS9488.1 STK24 gene_id:8428|Hs108|chr13          ( 443)  791 71.3 6.7e-12
CCDS47900.1 STK3 gene_id:6788|Hs108|chr8           ( 491)  779 70.5 1.3e-11
CCDS59108.1 STK3 gene_id:6788|Hs108|chr8           ( 519)  779 70.5 1.4e-11
CCDS34290.1 STK10 gene_id:6793|Hs108|chr5          ( 968)  780 70.7 2.2e-11
CCDS63200.1 STK25 gene_id:10494|Hs108|chr2         ( 349)  740 67.7 6.5e-11
CCDS48168.1 STK26 gene_id:51765|Hs108|chrX         ( 339)  733 67.2 8.9e-11


>>CCDS46956.1 TNIK gene_id:23043|Hs108|chr3               (1360 aa)
 initn: 9018 init1: 9018 opt: 9018  Z-score: 3420.6  bits: 645.3 E(32554): 3.3e-184
Smith-Waterman score: 9018; 100.0% identity (100.0% similar) in 1360 aa overlap (1-1360:1-1360)

               10        20        30        40        50        60
pF1KA0 MASDSPARSLDEIDLSALRDPAGIFELVELVGNGTYGQVYKGRHVKTGQLAAIKVMDVTG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS46 MASDSPARSLDEIDLSALRDPAGIFELVELVGNGTYGQVYKGRHVKTGQLAAIKVMDVTG
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KA0 DEEEEIKQEINMLKKYSHHRNIATYYGAFIKKNPPGMDDQLWLVMEFCGAGSVTDLIKNT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS46 DEEEEIKQEINMLKKYSHHRNIATYYGAFIKKNPPGMDDQLWLVMEFCGAGSVTDLIKNT
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KA0 KGNTLKEEWIAYICREILRGLSHLHQHKVIHRDIKGQNVLLTENAEVKLVDFGVSAQLDR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS46 KGNTLKEEWIAYICREILRGLSHLHQHKVIHRDIKGQNVLLTENAEVKLVDFGVSAQLDR
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KA0 TVGRRNTFIGTPYWMAPEVIACDENPDATYDFKSDLWSLGITAIEMAEGAPPLCDMHPMR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS46 TVGRRNTFIGTPYWMAPEVIACDENPDATYDFKSDLWSLGITAIEMAEGAPPLCDMHPMR
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KA0 ALFLIPRNPAPRLKSKKWSKKFQSFIESCLVKNHSQRPATEQLMKHPFIRDQPNERQVRI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS46 ALFLIPRNPAPRLKSKKWSKKFQSFIESCLVKNHSQRPATEQLMKHPFIRDQPNERQVRI
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KA0 QLKDHIDRTKKKRGEKDETEYEYSGSEEEEEENDSGEPSSILNLPGESTLRRDFLRLQLA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS46 QLKDHIDRTKKKRGEKDETEYEYSGSEEEEEENDSGEPSSILNLPGESTLRRDFLRLQLA
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KA0 NKERSEALRRQQLEQQQRENEEHKRQLLAERQKRIEEQKEQRRRLEEQQRREKELRKQQE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS46 NKERSEALRRQQLEQQQRENEEHKRQLLAERQKRIEEQKEQRRRLEEQQRREKELRKQQE
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KA0 REQRRHYEEQMRREEERRRAEHEQEYIRRQLEEEQRQLEILQQQLLHEQALLLEYKRKQL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS46 REQRRHYEEQMRREEERRRAEHEQEYIRRQLEEEQRQLEILQQQLLHEQALLLEYKRKQL
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KA0 EEQRQAERLQRQLKQERDYLVSLQHQRQEQRPVEKKPLYHYKEGMSPSEKPAWAKEVEER
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS46 EEQRQAERLQRQLKQERDYLVSLQHQRQEQRPVEKKPLYHYKEGMSPSEKPAWAKEVEER
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KA0 SRLNRQSSPAMPHKVANRISDPNLPPRSESFSISGVQPARTPPMLRPVDPQIPHLVAVKS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS46 SRLNRQSSPAMPHKVANRISDPNLPPRSESFSISGVQPARTPPMLRPVDPQIPHLVAVKS
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KA0 QGPALTASQSVHEQPTKGLSGFQEALNVTSHRVEMPRQNSDPTSENPPLPTRIEKFDRSS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS46 QGPALTASQSVHEQPTKGLSGFQEALNVTSHRVEMPRQNSDPTSENPPLPTRIEKFDRSS
              610       620       630       640       650       660

              670       680       690       700       710       720
pF1KA0 WLRQEEDIPPKVPQRTTSISPALARKNSPGNGSALGPRLGSQPIRASNPDLRRTEPILES
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS46 WLRQEEDIPPKVPQRTTSISPALARKNSPGNGSALGPRLGSQPIRASNPDLRRTEPILES
              670       680       690       700       710       720

              730       740       750       760       770       780
pF1KA0 PLQRTSSGSSSSSSTPSSQPSSQGGSQPGSQAGSSERTRVRANSKSEGSPVLPHEPAKVK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS46 PLQRTSSGSSSSSSTPSSQPSSQGGSQPGSQAGSSERTRVRANSKSEGSPVLPHEPAKVK
              730       740       750       760       770       780

              790       800       810       820       830       840
pF1KA0 PEESRDITRPSRPASYKKAIDEDLTALAKELRELRIEETNRPMKKVTDYSSSSEESESSE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS46 PEESRDITRPSRPASYKKAIDEDLTALAKELRELRIEETNRPMKKVTDYSSSSEESESSE
              790       800       810       820       830       840

              850       860       870       880       890       900
pF1KA0 EEEEDGESETHDGTVAVSDIPRLIPTGAPGSNEQYNVGMVGTHGLETSHADSFSGSISRE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS46 EEEEDGESETHDGTVAVSDIPRLIPTGAPGSNEQYNVGMVGTHGLETSHADSFSGSISRE
              850       860       870       880       890       900

              910       920       930       940       950       960
pF1KA0 GTLMIRETSGEKKRSGHSDSNGFAGHINLPDLVQQSHSPAGTPTEGLGRVSTHSQEMDSG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS46 GTLMIRETSGEKKRSGHSDSNGFAGHINLPDLVQQSHSPAGTPTEGLGRVSTHSQEMDSG
              910       920       930       940       950       960

              970       980       990      1000      1010      1020
pF1KA0 TEYGMGSSTKASFTPFVDPRVYQTSPTDEDEEDEESSAAALFTSELLRQEQAKLNEARKI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS46 TEYGMGSSTKASFTPFVDPRVYQTSPTDEDEEDEESSAAALFTSELLRQEQAKLNEARKI
              970       980       990      1000      1010      1020

             1030      1040      1050      1060      1070      1080
pF1KA0 SVVNVNPTNIRPHSDTPEIRKYKKRFNSEILCAALWGVNLLVGTENGLMLLDRSGQGKVY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS46 SVVNVNPTNIRPHSDTPEIRKYKKRFNSEILCAALWGVNLLVGTENGLMLLDRSGQGKVY
             1030      1040      1050      1060      1070      1080

             1090      1100      1110      1120      1130      1140
pF1KA0 NLINRRRFQQMDVLEGLNVLVTISGKKNKLRVYYLSWLRNRILHNDPEVEKKQGWITVGD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS46 NLINRRRFQQMDVLEGLNVLVTISGKKNKLRVYYLSWLRNRILHNDPEVEKKQGWITVGD
             1090      1100      1110      1120      1130      1140

             1150      1160      1170      1180      1190      1200
pF1KA0 LEGCIHYKVVKYERIKFLVIALKNAVEIYAWAPKPYHKFMAFKSFADLQHKPLLVDLTVE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS46 LEGCIHYKVVKYERIKFLVIALKNAVEIYAWAPKPYHKFMAFKSFADLQHKPLLVDLTVE
             1150      1160      1170      1180      1190      1200

             1210      1220      1230      1240      1250      1260
pF1KA0 EGQRLKVIFGSHTGFHVIDVDSGNSYDIYIPSHIQGNITPHAIVILPKTDGMEMLVCYED
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS46 EGQRLKVIFGSHTGFHVIDVDSGNSYDIYIPSHIQGNITPHAIVILPKTDGMEMLVCYED
             1210      1220      1230      1240      1250      1260

             1270      1280      1290      1300      1310      1320
pF1KA0 EGVYVNTYGRITKDVVLQWGEMPTSVAYIHSNQIMGWGEKAIEIRSVETGHLDGVFMHKR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS46 EGVYVNTYGRITKDVVLQWGEMPTSVAYIHSNQIMGWGEKAIEIRSVETGHLDGVFMHKR
             1270      1280      1290      1300      1310      1320

             1330      1340      1350      1360
pF1KA0 AQRLKFLCERNDKVFFASVRSGGSSQVFFMTLNRNSMMNW
       ::::::::::::::::::::::::::::::::::::::::
CCDS46 AQRLKFLCERNDKVFFASVRSGGSSQVFFMTLNRNSMMNW
             1330      1340      1350      1360

>>CCDS54679.1 TNIK gene_id:23043|Hs108|chr3               (1352 aa)
 initn: 5289 init1: 5289 opt: 8943  Z-score: 3392.3  bits: 640.1 E(32554): 1.2e-182
Smith-Waterman score: 8943; 99.4% identity (99.4% similar) in 1360 aa overlap (1-1360:1-1352)

               10        20        30        40        50        60
pF1KA0 MASDSPARSLDEIDLSALRDPAGIFELVELVGNGTYGQVYKGRHVKTGQLAAIKVMDVTG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 MASDSPARSLDEIDLSALRDPAGIFELVELVGNGTYGQVYKGRHVKTGQLAAIKVMDVTG
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KA0 DEEEEIKQEINMLKKYSHHRNIATYYGAFIKKNPPGMDDQLWLVMEFCGAGSVTDLIKNT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 DEEEEIKQEINMLKKYSHHRNIATYYGAFIKKNPPGMDDQLWLVMEFCGAGSVTDLIKNT
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KA0 KGNTLKEEWIAYICREILRGLSHLHQHKVIHRDIKGQNVLLTENAEVKLVDFGVSAQLDR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 KGNTLKEEWIAYICREILRGLSHLHQHKVIHRDIKGQNVLLTENAEVKLVDFGVSAQLDR
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KA0 TVGRRNTFIGTPYWMAPEVIACDENPDATYDFKSDLWSLGITAIEMAEGAPPLCDMHPMR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 TVGRRNTFIGTPYWMAPEVIACDENPDATYDFKSDLWSLGITAIEMAEGAPPLCDMHPMR
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KA0 ALFLIPRNPAPRLKSKKWSKKFQSFIESCLVKNHSQRPATEQLMKHPFIRDQPNERQVRI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 ALFLIPRNPAPRLKSKKWSKKFQSFIESCLVKNHSQRPATEQLMKHPFIRDQPNERQVRI
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KA0 QLKDHIDRTKKKRGEKDETEYEYSGSEEEEEENDSGEPSSILNLPGESTLRRDFLRLQLA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 QLKDHIDRTKKKRGEKDETEYEYSGSEEEEEENDSGEPSSILNLPGESTLRRDFLRLQLA
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KA0 NKERSEALRRQQLEQQQRENEEHKRQLLAERQKRIEEQKEQRRRLEEQQRREKELRKQQE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 NKERSEALRRQQLEQQQRENEEHKRQLLAERQKRIEEQKEQRRRLEEQQRREKELRKQQE
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KA0 REQRRHYEEQMRREEERRRAEHEQEYIRRQLEEEQRQLEILQQQLLHEQALLLEYKRKQL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 REQRRHYEEQMRREEERRRAEHEQEYIRRQLEEEQRQLEILQQQLLHEQALLLEYKRKQL
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KA0 EEQRQAERLQRQLKQERDYLVSLQHQRQEQRPVEKKPLYHYKEGMSPSEKPAWAKEVEER
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 EEQRQAERLQRQLKQERDYLVSLQHQRQEQRPVEKKPLYHYKEGMSPSEKPAWAKEVEER
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KA0 SRLNRQSSPAMPHKVANRISDPNLPPRSESFSISGVQPARTPPMLRPVDPQIPHLVAVKS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 SRLNRQSSPAMPHKVANRISDPNLPPRSESFSISGVQPARTPPMLRPVDPQIPHLVAVKS
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KA0 QGPALTASQSVHEQPTKGLSGFQEALNVTSHRVEMPRQNSDPTSENPPLPTRIEKFDRSS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 QGPALTASQSVHEQPTKGLSGFQEALNVTSHRVEMPRQNSDPTSENPPLPTRIEKFDRSS
              610       620       630       640       650       660

              670       680       690       700       710       720
pF1KA0 WLRQEEDIPPKVPQRTTSISPALARKNSPGNGSALGPRLGSQPIRASNPDLRRTEPILES
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 WLRQEEDIPPKVPQRTTSISPALARKNSPGNGSALGPRLGSQPIRASNPDLRRTEPILES
              670       680       690       700       710       720

              730       740       750       760       770       780
pF1KA0 PLQRTSSGSSSSSSTPSSQPSSQGGSQPGSQAGSSERTRVRANSKSEGSPVLPHEPAKVK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 PLQRTSSGSSSSSSTPSSQPSSQGGSQPGSQAGSSERTRVRANSKSEGSPVLPHEPAKVK
              730       740       750       760       770       780

              790       800       810       820       830       840
pF1KA0 PEESRDITRPSRPASYKKAIDEDLTALAKELRELRIEETNRPMKKVTDYSSSSEESESSE
       ::::::::::::::        ::::::::::::::::::::::::::::::::::::::
CCDS54 PEESRDITRPSRPA--------DLTALAKELRELRIEETNRPMKKVTDYSSSSEESESSE
              790               800       810       820       830  

              850       860       870       880       890       900
pF1KA0 EEEEDGESETHDGTVAVSDIPRLIPTGAPGSNEQYNVGMVGTHGLETSHADSFSGSISRE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 EEEEDGESETHDGTVAVSDIPRLIPTGAPGSNEQYNVGMVGTHGLETSHADSFSGSISRE
            840       850       860       870       880       890  

              910       920       930       940       950       960
pF1KA0 GTLMIRETSGEKKRSGHSDSNGFAGHINLPDLVQQSHSPAGTPTEGLGRVSTHSQEMDSG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 GTLMIRETSGEKKRSGHSDSNGFAGHINLPDLVQQSHSPAGTPTEGLGRVSTHSQEMDSG
            900       910       920       930       940       950  

              970       980       990      1000      1010      1020
pF1KA0 TEYGMGSSTKASFTPFVDPRVYQTSPTDEDEEDEESSAAALFTSELLRQEQAKLNEARKI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 TEYGMGSSTKASFTPFVDPRVYQTSPTDEDEEDEESSAAALFTSELLRQEQAKLNEARKI
            960       970       980       990      1000      1010  

             1030      1040      1050      1060      1070      1080
pF1KA0 SVVNVNPTNIRPHSDTPEIRKYKKRFNSEILCAALWGVNLLVGTENGLMLLDRSGQGKVY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 SVVNVNPTNIRPHSDTPEIRKYKKRFNSEILCAALWGVNLLVGTENGLMLLDRSGQGKVY
           1020      1030      1040      1050      1060      1070  

             1090      1100      1110      1120      1130      1140
pF1KA0 NLINRRRFQQMDVLEGLNVLVTISGKKNKLRVYYLSWLRNRILHNDPEVEKKQGWITVGD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 NLINRRRFQQMDVLEGLNVLVTISGKKNKLRVYYLSWLRNRILHNDPEVEKKQGWITVGD
           1080      1090      1100      1110      1120      1130  

             1150      1160      1170      1180      1190      1200
pF1KA0 LEGCIHYKVVKYERIKFLVIALKNAVEIYAWAPKPYHKFMAFKSFADLQHKPLLVDLTVE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 LEGCIHYKVVKYERIKFLVIALKNAVEIYAWAPKPYHKFMAFKSFADLQHKPLLVDLTVE
           1140      1150      1160      1170      1180      1190  

             1210      1220      1230      1240      1250      1260
pF1KA0 EGQRLKVIFGSHTGFHVIDVDSGNSYDIYIPSHIQGNITPHAIVILPKTDGMEMLVCYED
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 EGQRLKVIFGSHTGFHVIDVDSGNSYDIYIPSHIQGNITPHAIVILPKTDGMEMLVCYED
           1200      1210      1220      1230      1240      1250  

             1270      1280      1290      1300      1310      1320
pF1KA0 EGVYVNTYGRITKDVVLQWGEMPTSVAYIHSNQIMGWGEKAIEIRSVETGHLDGVFMHKR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 EGVYVNTYGRITKDVVLQWGEMPTSVAYIHSNQIMGWGEKAIEIRSVETGHLDGVFMHKR
           1260      1270      1280      1290      1300      1310  

             1330      1340      1350      1360
pF1KA0 AQRLKFLCERNDKVFFASVRSGGSSQVFFMTLNRNSMMNW
       ::::::::::::::::::::::::::::::::::::::::
CCDS54 AQRLKFLCERNDKVFFASVRSGGSSQVFFMTLNRNSMMNW
           1320      1330      1340      1350  

>>CCDS54676.1 TNIK gene_id:23043|Hs108|chr3               (1331 aa)
 initn: 5911 init1: 5911 opt: 6028  Z-score: 2293.8  bits: 436.8 E(32554): 1.9e-121
Smith-Waterman score: 8771; 97.9% identity (97.9% similar) in 1360 aa overlap (1-1360:1-1331)

               10        20        30        40        50        60
pF1KA0 MASDSPARSLDEIDLSALRDPAGIFELVELVGNGTYGQVYKGRHVKTGQLAAIKVMDVTG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 MASDSPARSLDEIDLSALRDPAGIFELVELVGNGTYGQVYKGRHVKTGQLAAIKVMDVTG
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KA0 DEEEEIKQEINMLKKYSHHRNIATYYGAFIKKNPPGMDDQLWLVMEFCGAGSVTDLIKNT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 DEEEEIKQEINMLKKYSHHRNIATYYGAFIKKNPPGMDDQLWLVMEFCGAGSVTDLIKNT
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KA0 KGNTLKEEWIAYICREILRGLSHLHQHKVIHRDIKGQNVLLTENAEVKLVDFGVSAQLDR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 KGNTLKEEWIAYICREILRGLSHLHQHKVIHRDIKGQNVLLTENAEVKLVDFGVSAQLDR
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KA0 TVGRRNTFIGTPYWMAPEVIACDENPDATYDFKSDLWSLGITAIEMAEGAPPLCDMHPMR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 TVGRRNTFIGTPYWMAPEVIACDENPDATYDFKSDLWSLGITAIEMAEGAPPLCDMHPMR
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KA0 ALFLIPRNPAPRLKSKKWSKKFQSFIESCLVKNHSQRPATEQLMKHPFIRDQPNERQVRI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 ALFLIPRNPAPRLKSKKWSKKFQSFIESCLVKNHSQRPATEQLMKHPFIRDQPNERQVRI
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KA0 QLKDHIDRTKKKRGEKDETEYEYSGSEEEEEENDSGEPSSILNLPGESTLRRDFLRLQLA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 QLKDHIDRTKKKRGEKDETEYEYSGSEEEEEENDSGEPSSILNLPGESTLRRDFLRLQLA
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KA0 NKERSEALRRQQLEQQQRENEEHKRQLLAERQKRIEEQKEQRRRLEEQQRREKELRKQQE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 NKERSEALRRQQLEQQQRENEEHKRQLLAERQKRIEEQKEQRRRLEEQQRREKELRKQQE
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KA0 REQRRHYEEQMRREEERRRAEHEQEYIRRQLEEEQRQLEILQQQLLHEQALLLEYKRKQL
       ::::::::::::::::::::::::::                             :::::
CCDS54 REQRRHYEEQMRREEERRRAEHEQEY-----------------------------KRKQL
              430       440                                    450 

              490       500       510       520       530       540
pF1KA0 EEQRQAERLQRQLKQERDYLVSLQHQRQEQRPVEKKPLYHYKEGMSPSEKPAWAKEVEER
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 EEQRQAERLQRQLKQERDYLVSLQHQRQEQRPVEKKPLYHYKEGMSPSEKPAWAKEVEER
             460       470       480       490       500       510 

              550       560       570       580       590       600
pF1KA0 SRLNRQSSPAMPHKVANRISDPNLPPRSESFSISGVQPARTPPMLRPVDPQIPHLVAVKS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 SRLNRQSSPAMPHKVANRISDPNLPPRSESFSISGVQPARTPPMLRPVDPQIPHLVAVKS
             520       530       540       550       560       570 

              610       620       630       640       650       660
pF1KA0 QGPALTASQSVHEQPTKGLSGFQEALNVTSHRVEMPRQNSDPTSENPPLPTRIEKFDRSS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 QGPALTASQSVHEQPTKGLSGFQEALNVTSHRVEMPRQNSDPTSENPPLPTRIEKFDRSS
             580       590       600       610       620       630 

              670       680       690       700       710       720
pF1KA0 WLRQEEDIPPKVPQRTTSISPALARKNSPGNGSALGPRLGSQPIRASNPDLRRTEPILES
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 WLRQEEDIPPKVPQRTTSISPALARKNSPGNGSALGPRLGSQPIRASNPDLRRTEPILES
             640       650       660       670       680       690 

              730       740       750       760       770       780
pF1KA0 PLQRTSSGSSSSSSTPSSQPSSQGGSQPGSQAGSSERTRVRANSKSEGSPVLPHEPAKVK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 PLQRTSSGSSSSSSTPSSQPSSQGGSQPGSQAGSSERTRVRANSKSEGSPVLPHEPAKVK
             700       710       720       730       740       750 

              790       800       810       820       830       840
pF1KA0 PEESRDITRPSRPASYKKAIDEDLTALAKELRELRIEETNRPMKKVTDYSSSSEESESSE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 PEESRDITRPSRPASYKKAIDEDLTALAKELRELRIEETNRPMKKVTDYSSSSEESESSE
             760       770       780       790       800       810 

              850       860       870       880       890       900
pF1KA0 EEEEDGESETHDGTVAVSDIPRLIPTGAPGSNEQYNVGMVGTHGLETSHADSFSGSISRE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 EEEEDGESETHDGTVAVSDIPRLIPTGAPGSNEQYNVGMVGTHGLETSHADSFSGSISRE
             820       830       840       850       860       870 

              910       920       930       940       950       960
pF1KA0 GTLMIRETSGEKKRSGHSDSNGFAGHINLPDLVQQSHSPAGTPTEGLGRVSTHSQEMDSG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 GTLMIRETSGEKKRSGHSDSNGFAGHINLPDLVQQSHSPAGTPTEGLGRVSTHSQEMDSG
             880       890       900       910       920       930 

              970       980       990      1000      1010      1020
pF1KA0 TEYGMGSSTKASFTPFVDPRVYQTSPTDEDEEDEESSAAALFTSELLRQEQAKLNEARKI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 TEYGMGSSTKASFTPFVDPRVYQTSPTDEDEEDEESSAAALFTSELLRQEQAKLNEARKI
             940       950       960       970       980       990 

             1030      1040      1050      1060      1070      1080
pF1KA0 SVVNVNPTNIRPHSDTPEIRKYKKRFNSEILCAALWGVNLLVGTENGLMLLDRSGQGKVY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 SVVNVNPTNIRPHSDTPEIRKYKKRFNSEILCAALWGVNLLVGTENGLMLLDRSGQGKVY
            1000      1010      1020      1030      1040      1050 

             1090      1100      1110      1120      1130      1140
pF1KA0 NLINRRRFQQMDVLEGLNVLVTISGKKNKLRVYYLSWLRNRILHNDPEVEKKQGWITVGD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 NLINRRRFQQMDVLEGLNVLVTISGKKNKLRVYYLSWLRNRILHNDPEVEKKQGWITVGD
            1060      1070      1080      1090      1100      1110 

             1150      1160      1170      1180      1190      1200
pF1KA0 LEGCIHYKVVKYERIKFLVIALKNAVEIYAWAPKPYHKFMAFKSFADLQHKPLLVDLTVE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 LEGCIHYKVVKYERIKFLVIALKNAVEIYAWAPKPYHKFMAFKSFADLQHKPLLVDLTVE
            1120      1130      1140      1150      1160      1170 

             1210      1220      1230      1240      1250      1260
pF1KA0 EGQRLKVIFGSHTGFHVIDVDSGNSYDIYIPSHIQGNITPHAIVILPKTDGMEMLVCYED
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 EGQRLKVIFGSHTGFHVIDVDSGNSYDIYIPSHIQGNITPHAIVILPKTDGMEMLVCYED
            1180      1190      1200      1210      1220      1230 

             1270      1280      1290      1300      1310      1320
pF1KA0 EGVYVNTYGRITKDVVLQWGEMPTSVAYIHSNQIMGWGEKAIEIRSVETGHLDGVFMHKR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 EGVYVNTYGRITKDVVLQWGEMPTSVAYIHSNQIMGWGEKAIEIRSVETGHLDGVFMHKR
            1240      1250      1260      1270      1280      1290 

             1330      1340      1350      1360
pF1KA0 AQRLKFLCERNDKVFFASVRSGGSSQVFFMTLNRNSMMNW
       ::::::::::::::::::::::::::::::::::::::::
CCDS54 AQRLKFLCERNDKVFFASVRSGGSSQVFFMTLNRNSMMNW
            1300      1310      1320      1330 

>>CCDS54675.1 TNIK gene_id:23043|Hs108|chr3               (1323 aa)
 initn: 6747 init1: 3742 opt: 5919  Z-score: 2252.8  bits: 429.2 E(32554): 3.7e-119
Smith-Waterman score: 8696; 97.3% identity (97.3% similar) in 1360 aa overlap (1-1360:1-1323)

               10        20        30        40        50        60
pF1KA0 MASDSPARSLDEIDLSALRDPAGIFELVELVGNGTYGQVYKGRHVKTGQLAAIKVMDVTG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 MASDSPARSLDEIDLSALRDPAGIFELVELVGNGTYGQVYKGRHVKTGQLAAIKVMDVTG
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KA0 DEEEEIKQEINMLKKYSHHRNIATYYGAFIKKNPPGMDDQLWLVMEFCGAGSVTDLIKNT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 DEEEEIKQEINMLKKYSHHRNIATYYGAFIKKNPPGMDDQLWLVMEFCGAGSVTDLIKNT
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KA0 KGNTLKEEWIAYICREILRGLSHLHQHKVIHRDIKGQNVLLTENAEVKLVDFGVSAQLDR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 KGNTLKEEWIAYICREILRGLSHLHQHKVIHRDIKGQNVLLTENAEVKLVDFGVSAQLDR
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KA0 TVGRRNTFIGTPYWMAPEVIACDENPDATYDFKSDLWSLGITAIEMAEGAPPLCDMHPMR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 TVGRRNTFIGTPYWMAPEVIACDENPDATYDFKSDLWSLGITAIEMAEGAPPLCDMHPMR
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KA0 ALFLIPRNPAPRLKSKKWSKKFQSFIESCLVKNHSQRPATEQLMKHPFIRDQPNERQVRI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 ALFLIPRNPAPRLKSKKWSKKFQSFIESCLVKNHSQRPATEQLMKHPFIRDQPNERQVRI
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KA0 QLKDHIDRTKKKRGEKDETEYEYSGSEEEEEENDSGEPSSILNLPGESTLRRDFLRLQLA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 QLKDHIDRTKKKRGEKDETEYEYSGSEEEEEENDSGEPSSILNLPGESTLRRDFLRLQLA
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KA0 NKERSEALRRQQLEQQQRENEEHKRQLLAERQKRIEEQKEQRRRLEEQQRREKELRKQQE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 NKERSEALRRQQLEQQQRENEEHKRQLLAERQKRIEEQKEQRRRLEEQQRREKELRKQQE
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KA0 REQRRHYEEQMRREEERRRAEHEQEYIRRQLEEEQRQLEILQQQLLHEQALLLEYKRKQL
       ::::::::::::::::::::::::::                             :::::
CCDS54 REQRRHYEEQMRREEERRRAEHEQEY-----------------------------KRKQL
              430       440                                    450 

              490       500       510       520       530       540
pF1KA0 EEQRQAERLQRQLKQERDYLVSLQHQRQEQRPVEKKPLYHYKEGMSPSEKPAWAKEVEER
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 EEQRQAERLQRQLKQERDYLVSLQHQRQEQRPVEKKPLYHYKEGMSPSEKPAWAKEVEER
             460       470       480       490       500       510 

              550       560       570       580       590       600
pF1KA0 SRLNRQSSPAMPHKVANRISDPNLPPRSESFSISGVQPARTPPMLRPVDPQIPHLVAVKS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 SRLNRQSSPAMPHKVANRISDPNLPPRSESFSISGVQPARTPPMLRPVDPQIPHLVAVKS
             520       530       540       550       560       570 

              610       620       630       640       650       660
pF1KA0 QGPALTASQSVHEQPTKGLSGFQEALNVTSHRVEMPRQNSDPTSENPPLPTRIEKFDRSS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 QGPALTASQSVHEQPTKGLSGFQEALNVTSHRVEMPRQNSDPTSENPPLPTRIEKFDRSS
             580       590       600       610       620       630 

              670       680       690       700       710       720
pF1KA0 WLRQEEDIPPKVPQRTTSISPALARKNSPGNGSALGPRLGSQPIRASNPDLRRTEPILES
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 WLRQEEDIPPKVPQRTTSISPALARKNSPGNGSALGPRLGSQPIRASNPDLRRTEPILES
             640       650       660       670       680       690 

              730       740       750       760       770       780
pF1KA0 PLQRTSSGSSSSSSTPSSQPSSQGGSQPGSQAGSSERTRVRANSKSEGSPVLPHEPAKVK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 PLQRTSSGSSSSSSTPSSQPSSQGGSQPGSQAGSSERTRVRANSKSEGSPVLPHEPAKVK
             700       710       720       730       740       750 

              790       800       810       820       830       840
pF1KA0 PEESRDITRPSRPASYKKAIDEDLTALAKELRELRIEETNRPMKKVTDYSSSSEESESSE
       ::::::::::::::        ::::::::::::::::::::::::::::::::::::::
CCDS54 PEESRDITRPSRPA--------DLTALAKELRELRIEETNRPMKKVTDYSSSSEESESSE
             760               770       780       790       800   

              850       860       870       880       890       900
pF1KA0 EEEEDGESETHDGTVAVSDIPRLIPTGAPGSNEQYNVGMVGTHGLETSHADSFSGSISRE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 EEEEDGESETHDGTVAVSDIPRLIPTGAPGSNEQYNVGMVGTHGLETSHADSFSGSISRE
           810       820       830       840       850       860   

              910       920       930       940       950       960
pF1KA0 GTLMIRETSGEKKRSGHSDSNGFAGHINLPDLVQQSHSPAGTPTEGLGRVSTHSQEMDSG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 GTLMIRETSGEKKRSGHSDSNGFAGHINLPDLVQQSHSPAGTPTEGLGRVSTHSQEMDSG
           870       880       890       900       910       920   

              970       980       990      1000      1010      1020
pF1KA0 TEYGMGSSTKASFTPFVDPRVYQTSPTDEDEEDEESSAAALFTSELLRQEQAKLNEARKI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 TEYGMGSSTKASFTPFVDPRVYQTSPTDEDEEDEESSAAALFTSELLRQEQAKLNEARKI
           930       940       950       960       970       980   

             1030      1040      1050      1060      1070      1080
pF1KA0 SVVNVNPTNIRPHSDTPEIRKYKKRFNSEILCAALWGVNLLVGTENGLMLLDRSGQGKVY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 SVVNVNPTNIRPHSDTPEIRKYKKRFNSEILCAALWGVNLLVGTENGLMLLDRSGQGKVY
           990      1000      1010      1020      1030      1040   

             1090      1100      1110      1120      1130      1140
pF1KA0 NLINRRRFQQMDVLEGLNVLVTISGKKNKLRVYYLSWLRNRILHNDPEVEKKQGWITVGD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 NLINRRRFQQMDVLEGLNVLVTISGKKNKLRVYYLSWLRNRILHNDPEVEKKQGWITVGD
          1050      1060      1070      1080      1090      1100   

             1150      1160      1170      1180      1190      1200
pF1KA0 LEGCIHYKVVKYERIKFLVIALKNAVEIYAWAPKPYHKFMAFKSFADLQHKPLLVDLTVE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 LEGCIHYKVVKYERIKFLVIALKNAVEIYAWAPKPYHKFMAFKSFADLQHKPLLVDLTVE
          1110      1120      1130      1140      1150      1160   

             1210      1220      1230      1240      1250      1260
pF1KA0 EGQRLKVIFGSHTGFHVIDVDSGNSYDIYIPSHIQGNITPHAIVILPKTDGMEMLVCYED
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 EGQRLKVIFGSHTGFHVIDVDSGNSYDIYIPSHIQGNITPHAIVILPKTDGMEMLVCYED
          1170      1180      1190      1200      1210      1220   

             1270      1280      1290      1300      1310      1320
pF1KA0 EGVYVNTYGRITKDVVLQWGEMPTSVAYIHSNQIMGWGEKAIEIRSVETGHLDGVFMHKR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 EGVYVNTYGRITKDVVLQWGEMPTSVAYIHSNQIMGWGEKAIEIRSVETGHLDGVFMHKR
          1230      1240      1250      1260      1270      1280   

             1330      1340      1350      1360
pF1KA0 AQRLKFLCERNDKVFFASVRSGGSSQVFFMTLNRNSMMNW
       ::::::::::::::::::::::::::::::::::::::::
CCDS54 AQRLKFLCERNDKVFFASVRSGGSSQVFFMTLNRNSMMNW
          1290      1300      1310      1320   

>>CCDS54678.1 TNIK gene_id:23043|Hs108|chr3               (1305 aa)
 initn: 5073 init1: 5073 opt: 5232  Z-score: 1994.0  bits: 381.3 E(32554): 9.6e-105
Smith-Waterman score: 8522; 96.0% identity (96.0% similar) in 1360 aa overlap (1-1360:1-1305)

               10        20        30        40        50        60
pF1KA0 MASDSPARSLDEIDLSALRDPAGIFELVELVGNGTYGQVYKGRHVKTGQLAAIKVMDVTG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 MASDSPARSLDEIDLSALRDPAGIFELVELVGNGTYGQVYKGRHVKTGQLAAIKVMDVTG
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KA0 DEEEEIKQEINMLKKYSHHRNIATYYGAFIKKNPPGMDDQLWLVMEFCGAGSVTDLIKNT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 DEEEEIKQEINMLKKYSHHRNIATYYGAFIKKNPPGMDDQLWLVMEFCGAGSVTDLIKNT
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KA0 KGNTLKEEWIAYICREILRGLSHLHQHKVIHRDIKGQNVLLTENAEVKLVDFGVSAQLDR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 KGNTLKEEWIAYICREILRGLSHLHQHKVIHRDIKGQNVLLTENAEVKLVDFGVSAQLDR
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KA0 TVGRRNTFIGTPYWMAPEVIACDENPDATYDFKSDLWSLGITAIEMAEGAPPLCDMHPMR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 TVGRRNTFIGTPYWMAPEVIACDENPDATYDFKSDLWSLGITAIEMAEGAPPLCDMHPMR
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KA0 ALFLIPRNPAPRLKSKKWSKKFQSFIESCLVKNHSQRPATEQLMKHPFIRDQPNERQVRI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 ALFLIPRNPAPRLKSKKWSKKFQSFIESCLVKNHSQRPATEQLMKHPFIRDQPNERQVRI
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KA0 QLKDHIDRTKKKRGEKDETEYEYSGSEEEEEENDSGEPSSILNLPGESTLRRDFLRLQLA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 QLKDHIDRTKKKRGEKDETEYEYSGSEEEEEENDSGEPSSILNLPGESTLRRDFLRLQLA
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KA0 NKERSEALRRQQLEQQQRENEEHKRQLLAERQKRIEEQKEQRRRLEEQQRREKELRKQQE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 NKERSEALRRQQLEQQQRENEEHKRQLLAERQKRIEEQKEQRRRLEEQQRREKELRKQQE
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KA0 REQRRHYEEQMRREEERRRAEHEQEYIRRQLEEEQRQLEILQQQLLHEQALLLEYKRKQL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 REQRRHYEEQMRREEERRRAEHEQEYIRRQLEEEQRQLEILQQQLLHEQALLLEYKRKQL
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KA0 EEQRQAERLQRQLKQERDYLVSLQHQRQEQRPVEKKPLYHYKEGMSPSEKPAWAKEVEER
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::    
CCDS54 EEQRQAERLQRQLKQERDYLVSLQHQRQEQRPVEKKPLYHYKEGMSPSEKPAWAKE----
              490       500       510       520       530          

              550       560       570       580       590       600
pF1KA0 SRLNRQSSPAMPHKVANRISDPNLPPRSESFSISGVQPARTPPMLRPVDPQIPHLVAVKS
                                                          :::::::::
CCDS54 ---------------------------------------------------IPHLVAVKS
                                                           540     

              610       620       630       640       650       660
pF1KA0 QGPALTASQSVHEQPTKGLSGFQEALNVTSHRVEMPRQNSDPTSENPPLPTRIEKFDRSS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 QGPALTASQSVHEQPTKGLSGFQEALNVTSHRVEMPRQNSDPTSENPPLPTRIEKFDRSS
         550       560       570       580       590       600     

              670       680       690       700       710       720
pF1KA0 WLRQEEDIPPKVPQRTTSISPALARKNSPGNGSALGPRLGSQPIRASNPDLRRTEPILES
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 WLRQEEDIPPKVPQRTTSISPALARKNSPGNGSALGPRLGSQPIRASNPDLRRTEPILES
         610       620       630       640       650       660     

              730       740       750       760       770       780
pF1KA0 PLQRTSSGSSSSSSTPSSQPSSQGGSQPGSQAGSSERTRVRANSKSEGSPVLPHEPAKVK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 PLQRTSSGSSSSSSTPSSQPSSQGGSQPGSQAGSSERTRVRANSKSEGSPVLPHEPAKVK
         670       680       690       700       710       720     

              790       800       810       820       830       840
pF1KA0 PEESRDITRPSRPASYKKAIDEDLTALAKELRELRIEETNRPMKKVTDYSSSSEESESSE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 PEESRDITRPSRPASYKKAIDEDLTALAKELRELRIEETNRPMKKVTDYSSSSEESESSE
         730       740       750       760       770       780     

              850       860       870       880       890       900
pF1KA0 EEEEDGESETHDGTVAVSDIPRLIPTGAPGSNEQYNVGMVGTHGLETSHADSFSGSISRE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 EEEEDGESETHDGTVAVSDIPRLIPTGAPGSNEQYNVGMVGTHGLETSHADSFSGSISRE
         790       800       810       820       830       840     

              910       920       930       940       950       960
pF1KA0 GTLMIRETSGEKKRSGHSDSNGFAGHINLPDLVQQSHSPAGTPTEGLGRVSTHSQEMDSG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 GTLMIRETSGEKKRSGHSDSNGFAGHINLPDLVQQSHSPAGTPTEGLGRVSTHSQEMDSG
         850       860       870       880       890       900     

              970       980       990      1000      1010      1020
pF1KA0 TEYGMGSSTKASFTPFVDPRVYQTSPTDEDEEDEESSAAALFTSELLRQEQAKLNEARKI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 TEYGMGSSTKASFTPFVDPRVYQTSPTDEDEEDEESSAAALFTSELLRQEQAKLNEARKI
         910       920       930       940       950       960     

             1030      1040      1050      1060      1070      1080
pF1KA0 SVVNVNPTNIRPHSDTPEIRKYKKRFNSEILCAALWGVNLLVGTENGLMLLDRSGQGKVY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 SVVNVNPTNIRPHSDTPEIRKYKKRFNSEILCAALWGVNLLVGTENGLMLLDRSGQGKVY
         970       980       990      1000      1010      1020     

             1090      1100      1110      1120      1130      1140
pF1KA0 NLINRRRFQQMDVLEGLNVLVTISGKKNKLRVYYLSWLRNRILHNDPEVEKKQGWITVGD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 NLINRRRFQQMDVLEGLNVLVTISGKKNKLRVYYLSWLRNRILHNDPEVEKKQGWITVGD
        1030      1040      1050      1060      1070      1080     

             1150      1160      1170      1180      1190      1200
pF1KA0 LEGCIHYKVVKYERIKFLVIALKNAVEIYAWAPKPYHKFMAFKSFADLQHKPLLVDLTVE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 LEGCIHYKVVKYERIKFLVIALKNAVEIYAWAPKPYHKFMAFKSFADLQHKPLLVDLTVE
        1090      1100      1110      1120      1130      1140     

             1210      1220      1230      1240      1250      1260
pF1KA0 EGQRLKVIFGSHTGFHVIDVDSGNSYDIYIPSHIQGNITPHAIVILPKTDGMEMLVCYED
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 EGQRLKVIFGSHTGFHVIDVDSGNSYDIYIPSHIQGNITPHAIVILPKTDGMEMLVCYED
        1150      1160      1170      1180      1190      1200     

             1270      1280      1290      1300      1310      1320
pF1KA0 EGVYVNTYGRITKDVVLQWGEMPTSVAYIHSNQIMGWGEKAIEIRSVETGHLDGVFMHKR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 EGVYVNTYGRITKDVVLQWGEMPTSVAYIHSNQIMGWGEKAIEIRSVETGHLDGVFMHKR
        1210      1220      1230      1240      1250      1260     

             1330      1340      1350      1360
pF1KA0 AQRLKFLCERNDKVFFASVRSGGSSQVFFMTLNRNSMMNW
       ::::::::::::::::::::::::::::::::::::::::
CCDS54 AQRLKFLCERNDKVFFASVRSGGSSQVFFMTLNRNSMMNW
        1270      1280      1290      1300     

>>CCDS54674.1 TNIK gene_id:23043|Hs108|chr3               (1276 aa)
 initn: 8078 init1: 5073 opt: 5217  Z-score: 1988.4  bits: 380.2 E(32554): 1.9e-104
Smith-Waterman score: 8275; 93.8% identity (93.8% similar) in 1360 aa overlap (1-1360:1-1276)

               10        20        30        40        50        60
pF1KA0 MASDSPARSLDEIDLSALRDPAGIFELVELVGNGTYGQVYKGRHVKTGQLAAIKVMDVTG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 MASDSPARSLDEIDLSALRDPAGIFELVELVGNGTYGQVYKGRHVKTGQLAAIKVMDVTG
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KA0 DEEEEIKQEINMLKKYSHHRNIATYYGAFIKKNPPGMDDQLWLVMEFCGAGSVTDLIKNT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 DEEEEIKQEINMLKKYSHHRNIATYYGAFIKKNPPGMDDQLWLVMEFCGAGSVTDLIKNT
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KA0 KGNTLKEEWIAYICREILRGLSHLHQHKVIHRDIKGQNVLLTENAEVKLVDFGVSAQLDR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 KGNTLKEEWIAYICREILRGLSHLHQHKVIHRDIKGQNVLLTENAEVKLVDFGVSAQLDR
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KA0 TVGRRNTFIGTPYWMAPEVIACDENPDATYDFKSDLWSLGITAIEMAEGAPPLCDMHPMR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 TVGRRNTFIGTPYWMAPEVIACDENPDATYDFKSDLWSLGITAIEMAEGAPPLCDMHPMR
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KA0 ALFLIPRNPAPRLKSKKWSKKFQSFIESCLVKNHSQRPATEQLMKHPFIRDQPNERQVRI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 ALFLIPRNPAPRLKSKKWSKKFQSFIESCLVKNHSQRPATEQLMKHPFIRDQPNERQVRI
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KA0 QLKDHIDRTKKKRGEKDETEYEYSGSEEEEEENDSGEPSSILNLPGESTLRRDFLRLQLA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 QLKDHIDRTKKKRGEKDETEYEYSGSEEEEEENDSGEPSSILNLPGESTLRRDFLRLQLA
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KA0 NKERSEALRRQQLEQQQRENEEHKRQLLAERQKRIEEQKEQRRRLEEQQRREKELRKQQE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 NKERSEALRRQQLEQQQRENEEHKRQLLAERQKRIEEQKEQRRRLEEQQRREKELRKQQE
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KA0 REQRRHYEEQMRREEERRRAEHEQEYIRRQLEEEQRQLEILQQQLLHEQALLLEYKRKQL
       ::::::::::::::::::::::::::                             :::::
CCDS54 REQRRHYEEQMRREEERRRAEHEQEY-----------------------------KRKQL
              430       440                                    450 

              490       500       510       520       530       540
pF1KA0 EEQRQAERLQRQLKQERDYLVSLQHQRQEQRPVEKKPLYHYKEGMSPSEKPAWAKEVEER
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::    
CCDS54 EEQRQAERLQRQLKQERDYLVSLQHQRQEQRPVEKKPLYHYKEGMSPSEKPAWAKE----
             460       470       480       490       500           

              550       560       570       580       590       600
pF1KA0 SRLNRQSSPAMPHKVANRISDPNLPPRSESFSISGVQPARTPPMLRPVDPQIPHLVAVKS
                                                          :::::::::
CCDS54 ---------------------------------------------------IPHLVAVKS
                                                          510      

              610       620       630       640       650       660
pF1KA0 QGPALTASQSVHEQPTKGLSGFQEALNVTSHRVEMPRQNSDPTSENPPLPTRIEKFDRSS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 QGPALTASQSVHEQPTKGLSGFQEALNVTSHRVEMPRQNSDPTSENPPLPTRIEKFDRSS
        520       530       540       550       560       570      

              670       680       690       700       710       720
pF1KA0 WLRQEEDIPPKVPQRTTSISPALARKNSPGNGSALGPRLGSQPIRASNPDLRRTEPILES
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 WLRQEEDIPPKVPQRTTSISPALARKNSPGNGSALGPRLGSQPIRASNPDLRRTEPILES
        580       590       600       610       620       630      

              730       740       750       760       770       780
pF1KA0 PLQRTSSGSSSSSSTPSSQPSSQGGSQPGSQAGSSERTRVRANSKSEGSPVLPHEPAKVK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 PLQRTSSGSSSSSSTPSSQPSSQGGSQPGSQAGSSERTRVRANSKSEGSPVLPHEPAKVK
        640       650       660       670       680       690      

              790       800       810       820       830       840
pF1KA0 PEESRDITRPSRPASYKKAIDEDLTALAKELRELRIEETNRPMKKVTDYSSSSEESESSE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 PEESRDITRPSRPASYKKAIDEDLTALAKELRELRIEETNRPMKKVTDYSSSSEESESSE
        700       710       720       730       740       750      

              850       860       870       880       890       900
pF1KA0 EEEEDGESETHDGTVAVSDIPRLIPTGAPGSNEQYNVGMVGTHGLETSHADSFSGSISRE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 EEEEDGESETHDGTVAVSDIPRLIPTGAPGSNEQYNVGMVGTHGLETSHADSFSGSISRE
        760       770       780       790       800       810      

              910       920       930       940       950       960
pF1KA0 GTLMIRETSGEKKRSGHSDSNGFAGHINLPDLVQQSHSPAGTPTEGLGRVSTHSQEMDSG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 GTLMIRETSGEKKRSGHSDSNGFAGHINLPDLVQQSHSPAGTPTEGLGRVSTHSQEMDSG
        820       830       840       850       860       870      

              970       980       990      1000      1010      1020
pF1KA0 TEYGMGSSTKASFTPFVDPRVYQTSPTDEDEEDEESSAAALFTSELLRQEQAKLNEARKI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 TEYGMGSSTKASFTPFVDPRVYQTSPTDEDEEDEESSAAALFTSELLRQEQAKLNEARKI
        880       890       900       910       920       930      

             1030      1040      1050      1060      1070      1080
pF1KA0 SVVNVNPTNIRPHSDTPEIRKYKKRFNSEILCAALWGVNLLVGTENGLMLLDRSGQGKVY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 SVVNVNPTNIRPHSDTPEIRKYKKRFNSEILCAALWGVNLLVGTENGLMLLDRSGQGKVY
        940       950       960       970       980       990      

             1090      1100      1110      1120      1130      1140
pF1KA0 NLINRRRFQQMDVLEGLNVLVTISGKKNKLRVYYLSWLRNRILHNDPEVEKKQGWITVGD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 NLINRRRFQQMDVLEGLNVLVTISGKKNKLRVYYLSWLRNRILHNDPEVEKKQGWITVGD
       1000      1010      1020      1030      1040      1050      

             1150      1160      1170      1180      1190      1200
pF1KA0 LEGCIHYKVVKYERIKFLVIALKNAVEIYAWAPKPYHKFMAFKSFADLQHKPLLVDLTVE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 LEGCIHYKVVKYERIKFLVIALKNAVEIYAWAPKPYHKFMAFKSFADLQHKPLLVDLTVE
       1060      1070      1080      1090      1100      1110      

             1210      1220      1230      1240      1250      1260
pF1KA0 EGQRLKVIFGSHTGFHVIDVDSGNSYDIYIPSHIQGNITPHAIVILPKTDGMEMLVCYED
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 EGQRLKVIFGSHTGFHVIDVDSGNSYDIYIPSHIQGNITPHAIVILPKTDGMEMLVCYED
       1120      1130      1140      1150      1160      1170      

             1270      1280      1290      1300      1310      1320
pF1KA0 EGVYVNTYGRITKDVVLQWGEMPTSVAYIHSNQIMGWGEKAIEIRSVETGHLDGVFMHKR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 EGVYVNTYGRITKDVVLQWGEMPTSVAYIHSNQIMGWGEKAIEIRSVETGHLDGVFMHKR
       1180      1190      1200      1210      1220      1230      

             1330      1340      1350      1360
pF1KA0 AQRLKFLCERNDKVFFASVRSGGSSQVFFMTLNRNSMMNW
       ::::::::::::::::::::::::::::::::::::::::
CCDS54 AQRLKFLCERNDKVFFASVRSGGSSQVFFMTLNRNSMMNW
       1240      1250      1260      1270      

>>CCDS54673.1 TNIK gene_id:23043|Hs108|chr3               (1268 aa)
 initn: 6747 init1: 3742 opt: 5122  Z-score: 1952.7  bits: 373.6 E(32554): 1.9e-102
Smith-Waterman score: 8200; 93.2% identity (93.2% similar) in 1360 aa overlap (1-1360:1-1268)

               10        20        30        40        50        60
pF1KA0 MASDSPARSLDEIDLSALRDPAGIFELVELVGNGTYGQVYKGRHVKTGQLAAIKVMDVTG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 MASDSPARSLDEIDLSALRDPAGIFELVELVGNGTYGQVYKGRHVKTGQLAAIKVMDVTG
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KA0 DEEEEIKQEINMLKKYSHHRNIATYYGAFIKKNPPGMDDQLWLVMEFCGAGSVTDLIKNT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 DEEEEIKQEINMLKKYSHHRNIATYYGAFIKKNPPGMDDQLWLVMEFCGAGSVTDLIKNT
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KA0 KGNTLKEEWIAYICREILRGLSHLHQHKVIHRDIKGQNVLLTENAEVKLVDFGVSAQLDR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 KGNTLKEEWIAYICREILRGLSHLHQHKVIHRDIKGQNVLLTENAEVKLVDFGVSAQLDR
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KA0 TVGRRNTFIGTPYWMAPEVIACDENPDATYDFKSDLWSLGITAIEMAEGAPPLCDMHPMR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 TVGRRNTFIGTPYWMAPEVIACDENPDATYDFKSDLWSLGITAIEMAEGAPPLCDMHPMR
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KA0 ALFLIPRNPAPRLKSKKWSKKFQSFIESCLVKNHSQRPATEQLMKHPFIRDQPNERQVRI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 ALFLIPRNPAPRLKSKKWSKKFQSFIESCLVKNHSQRPATEQLMKHPFIRDQPNERQVRI
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KA0 QLKDHIDRTKKKRGEKDETEYEYSGSEEEEEENDSGEPSSILNLPGESTLRRDFLRLQLA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 QLKDHIDRTKKKRGEKDETEYEYSGSEEEEEENDSGEPSSILNLPGESTLRRDFLRLQLA
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KA0 NKERSEALRRQQLEQQQRENEEHKRQLLAERQKRIEEQKEQRRRLEEQQRREKELRKQQE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 NKERSEALRRQQLEQQQRENEEHKRQLLAERQKRIEEQKEQRRRLEEQQRREKELRKQQE
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KA0 REQRRHYEEQMRREEERRRAEHEQEYIRRQLEEEQRQLEILQQQLLHEQALLLEYKRKQL
       ::::::::::::::::::::::::::                             :::::
CCDS54 REQRRHYEEQMRREEERRRAEHEQEY-----------------------------KRKQL
              430       440                                    450 

              490       500       510       520       530       540
pF1KA0 EEQRQAERLQRQLKQERDYLVSLQHQRQEQRPVEKKPLYHYKEGMSPSEKPAWAKEVEER
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::    
CCDS54 EEQRQAERLQRQLKQERDYLVSLQHQRQEQRPVEKKPLYHYKEGMSPSEKPAWAKE----
             460       470       480       490       500           

              550       560       570       580       590       600
pF1KA0 SRLNRQSSPAMPHKVANRISDPNLPPRSESFSISGVQPARTPPMLRPVDPQIPHLVAVKS
                                                          :::::::::
CCDS54 ---------------------------------------------------IPHLVAVKS
                                                          510      

              610       620       630       640       650       660
pF1KA0 QGPALTASQSVHEQPTKGLSGFQEALNVTSHRVEMPRQNSDPTSENPPLPTRIEKFDRSS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 QGPALTASQSVHEQPTKGLSGFQEALNVTSHRVEMPRQNSDPTSENPPLPTRIEKFDRSS
        520       530       540       550       560       570      

              670       680       690       700       710       720
pF1KA0 WLRQEEDIPPKVPQRTTSISPALARKNSPGNGSALGPRLGSQPIRASNPDLRRTEPILES
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 WLRQEEDIPPKVPQRTTSISPALARKNSPGNGSALGPRLGSQPIRASNPDLRRTEPILES
        580       590       600       610       620       630      

              730       740       750       760       770       780
pF1KA0 PLQRTSSGSSSSSSTPSSQPSSQGGSQPGSQAGSSERTRVRANSKSEGSPVLPHEPAKVK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 PLQRTSSGSSSSSSTPSSQPSSQGGSQPGSQAGSSERTRVRANSKSEGSPVLPHEPAKVK
        640       650       660       670       680       690      

              790       800       810       820       830       840
pF1KA0 PEESRDITRPSRPASYKKAIDEDLTALAKELRELRIEETNRPMKKVTDYSSSSEESESSE
       ::::::::::::::        ::::::::::::::::::::::::::::::::::::::
CCDS54 PEESRDITRPSRPA--------DLTALAKELRELRIEETNRPMKKVTDYSSSSEESESSE
        700       710               720       730       740        

              850       860       870       880       890       900
pF1KA0 EEEEDGESETHDGTVAVSDIPRLIPTGAPGSNEQYNVGMVGTHGLETSHADSFSGSISRE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 EEEEDGESETHDGTVAVSDIPRLIPTGAPGSNEQYNVGMVGTHGLETSHADSFSGSISRE
      750       760       770       780       790       800        

              910       920       930       940       950       960
pF1KA0 GTLMIRETSGEKKRSGHSDSNGFAGHINLPDLVQQSHSPAGTPTEGLGRVSTHSQEMDSG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 GTLMIRETSGEKKRSGHSDSNGFAGHINLPDLVQQSHSPAGTPTEGLGRVSTHSQEMDSG
      810       820       830       840       850       860        

              970       980       990      1000      1010      1020
pF1KA0 TEYGMGSSTKASFTPFVDPRVYQTSPTDEDEEDEESSAAALFTSELLRQEQAKLNEARKI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 TEYGMGSSTKASFTPFVDPRVYQTSPTDEDEEDEESSAAALFTSELLRQEQAKLNEARKI
      870       880       890       900       910       920        

             1030      1040      1050      1060      1070      1080
pF1KA0 SVVNVNPTNIRPHSDTPEIRKYKKRFNSEILCAALWGVNLLVGTENGLMLLDRSGQGKVY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 SVVNVNPTNIRPHSDTPEIRKYKKRFNSEILCAALWGVNLLVGTENGLMLLDRSGQGKVY
      930       940       950       960       970       980        

             1090      1100      1110      1120      1130      1140
pF1KA0 NLINRRRFQQMDVLEGLNVLVTISGKKNKLRVYYLSWLRNRILHNDPEVEKKQGWITVGD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 NLINRRRFQQMDVLEGLNVLVTISGKKNKLRVYYLSWLRNRILHNDPEVEKKQGWITVGD
      990      1000      1010      1020      1030      1040        

             1150      1160      1170      1180      1190      1200
pF1KA0 LEGCIHYKVVKYERIKFLVIALKNAVEIYAWAPKPYHKFMAFKSFADLQHKPLLVDLTVE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 LEGCIHYKVVKYERIKFLVIALKNAVEIYAWAPKPYHKFMAFKSFADLQHKPLLVDLTVE
     1050      1060      1070      1080      1090      1100        

             1210      1220      1230      1240      1250      1260
pF1KA0 EGQRLKVIFGSHTGFHVIDVDSGNSYDIYIPSHIQGNITPHAIVILPKTDGMEMLVCYED
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 EGQRLKVIFGSHTGFHVIDVDSGNSYDIYIPSHIQGNITPHAIVILPKTDGMEMLVCYED
     1110      1120      1130      1140      1150      1160        

             1270      1280      1290      1300      1310      1320
pF1KA0 EGVYVNTYGRITKDVVLQWGEMPTSVAYIHSNQIMGWGEKAIEIRSVETGHLDGVFMHKR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 EGVYVNTYGRITKDVVLQWGEMPTSVAYIHSNQIMGWGEKAIEIRSVETGHLDGVFMHKR
     1170      1180      1190      1200      1210      1220        

             1330      1340      1350      1360
pF1KA0 AQRLKFLCERNDKVFFASVRSGGSSQVFFMTLNRNSMMNW
       ::::::::::::::::::::::::::::::::::::::::
CCDS54 AQRLKFLCERNDKVFFASVRSGGSSQVFFMTLNRNSMMNW
     1230      1240      1250      1260        

>>CCDS54677.1 TNIK gene_id:23043|Hs108|chr3               (1297 aa)
 initn: 7304 init1: 3742 opt: 5092  Z-score: 1941.2  bits: 371.5 E(32554): 8.3e-102
Smith-Waterman score: 8447; 95.4% identity (95.4% similar) in 1360 aa overlap (1-1360:1-1297)

               10        20        30        40        50        60
pF1KA0 MASDSPARSLDEIDLSALRDPAGIFELVELVGNGTYGQVYKGRHVKTGQLAAIKVMDVTG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 MASDSPARSLDEIDLSALRDPAGIFELVELVGNGTYGQVYKGRHVKTGQLAAIKVMDVTG
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KA0 DEEEEIKQEINMLKKYSHHRNIATYYGAFIKKNPPGMDDQLWLVMEFCGAGSVTDLIKNT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 DEEEEIKQEINMLKKYSHHRNIATYYGAFIKKNPPGMDDQLWLVMEFCGAGSVTDLIKNT
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KA0 KGNTLKEEWIAYICREILRGLSHLHQHKVIHRDIKGQNVLLTENAEVKLVDFGVSAQLDR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 KGNTLKEEWIAYICREILRGLSHLHQHKVIHRDIKGQNVLLTENAEVKLVDFGVSAQLDR
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KA0 TVGRRNTFIGTPYWMAPEVIACDENPDATYDFKSDLWSLGITAIEMAEGAPPLCDMHPMR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 TVGRRNTFIGTPYWMAPEVIACDENPDATYDFKSDLWSLGITAIEMAEGAPPLCDMHPMR
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KA0 ALFLIPRNPAPRLKSKKWSKKFQSFIESCLVKNHSQRPATEQLMKHPFIRDQPNERQVRI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 ALFLIPRNPAPRLKSKKWSKKFQSFIESCLVKNHSQRPATEQLMKHPFIRDQPNERQVRI
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KA0 QLKDHIDRTKKKRGEKDETEYEYSGSEEEEEENDSGEPSSILNLPGESTLRRDFLRLQLA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 QLKDHIDRTKKKRGEKDETEYEYSGSEEEEEENDSGEPSSILNLPGESTLRRDFLRLQLA
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KA0 NKERSEALRRQQLEQQQRENEEHKRQLLAERQKRIEEQKEQRRRLEEQQRREKELRKQQE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 NKERSEALRRQQLEQQQRENEEHKRQLLAERQKRIEEQKEQRRRLEEQQRREKELRKQQE
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KA0 REQRRHYEEQMRREEERRRAEHEQEYIRRQLEEEQRQLEILQQQLLHEQALLLEYKRKQL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 REQRRHYEEQMRREEERRRAEHEQEYIRRQLEEEQRQLEILQQQLLHEQALLLEYKRKQL
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KA0 EEQRQAERLQRQLKQERDYLVSLQHQRQEQRPVEKKPLYHYKEGMSPSEKPAWAKEVEER
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::    
CCDS54 EEQRQAERLQRQLKQERDYLVSLQHQRQEQRPVEKKPLYHYKEGMSPSEKPAWAKE----
              490       500       510       520       530          

              550       560       570       580       590       600
pF1KA0 SRLNRQSSPAMPHKVANRISDPNLPPRSESFSISGVQPARTPPMLRPVDPQIPHLVAVKS
                                                          :::::::::
CCDS54 ---------------------------------------------------IPHLVAVKS
                                                           540     

              610       620       630       640       650       660
pF1KA0 QGPALTASQSVHEQPTKGLSGFQEALNVTSHRVEMPRQNSDPTSENPPLPTRIEKFDRSS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 QGPALTASQSVHEQPTKGLSGFQEALNVTSHRVEMPRQNSDPTSENPPLPTRIEKFDRSS
         550       560       570       580       590       600     

              670       680       690       700       710       720
pF1KA0 WLRQEEDIPPKVPQRTTSISPALARKNSPGNGSALGPRLGSQPIRASNPDLRRTEPILES
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 WLRQEEDIPPKVPQRTTSISPALARKNSPGNGSALGPRLGSQPIRASNPDLRRTEPILES
         610       620       630       640       650       660     

              730       740       750       760       770       780
pF1KA0 PLQRTSSGSSSSSSTPSSQPSSQGGSQPGSQAGSSERTRVRANSKSEGSPVLPHEPAKVK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 PLQRTSSGSSSSSSTPSSQPSSQGGSQPGSQAGSSERTRVRANSKSEGSPVLPHEPAKVK
         670       680       690       700       710       720     

              790       800       810       820       830       840
pF1KA0 PEESRDITRPSRPASYKKAIDEDLTALAKELRELRIEETNRPMKKVTDYSSSSEESESSE
       ::::::::::::::        ::::::::::::::::::::::::::::::::::::::
CCDS54 PEESRDITRPSRPA--------DLTALAKELRELRIEETNRPMKKVTDYSSSSEESESSE
         730               740       750       760       770       

              850       860       870       880       890       900
pF1KA0 EEEEDGESETHDGTVAVSDIPRLIPTGAPGSNEQYNVGMVGTHGLETSHADSFSGSISRE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 EEEEDGESETHDGTVAVSDIPRLIPTGAPGSNEQYNVGMVGTHGLETSHADSFSGSISRE
       780       790       800       810       820       830       

              910       920       930       940       950       960
pF1KA0 GTLMIRETSGEKKRSGHSDSNGFAGHINLPDLVQQSHSPAGTPTEGLGRVSTHSQEMDSG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 GTLMIRETSGEKKRSGHSDSNGFAGHINLPDLVQQSHSPAGTPTEGLGRVSTHSQEMDSG
       840       850       860       870       880       890       

              970       980       990      1000      1010      1020
pF1KA0 TEYGMGSSTKASFTPFVDPRVYQTSPTDEDEEDEESSAAALFTSELLRQEQAKLNEARKI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 TEYGMGSSTKASFTPFVDPRVYQTSPTDEDEEDEESSAAALFTSELLRQEQAKLNEARKI
       900       910       920       930       940       950       

             1030      1040      1050      1060      1070      1080
pF1KA0 SVVNVNPTNIRPHSDTPEIRKYKKRFNSEILCAALWGVNLLVGTENGLMLLDRSGQGKVY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 SVVNVNPTNIRPHSDTPEIRKYKKRFNSEILCAALWGVNLLVGTENGLMLLDRSGQGKVY
       960       970       980       990      1000      1010       

             1090      1100      1110      1120      1130      1140
pF1KA0 NLINRRRFQQMDVLEGLNVLVTISGKKNKLRVYYLSWLRNRILHNDPEVEKKQGWITVGD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 NLINRRRFQQMDVLEGLNVLVTISGKKNKLRVYYLSWLRNRILHNDPEVEKKQGWITVGD
      1020      1030      1040      1050      1060      1070       

             1150      1160      1170      1180      1190      1200
pF1KA0 LEGCIHYKVVKYERIKFLVIALKNAVEIYAWAPKPYHKFMAFKSFADLQHKPLLVDLTVE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 LEGCIHYKVVKYERIKFLVIALKNAVEIYAWAPKPYHKFMAFKSFADLQHKPLLVDLTVE
      1080      1090      1100      1110      1120      1130       

             1210      1220      1230      1240      1250      1260
pF1KA0 EGQRLKVIFGSHTGFHVIDVDSGNSYDIYIPSHIQGNITPHAIVILPKTDGMEMLVCYED
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 EGQRLKVIFGSHTGFHVIDVDSGNSYDIYIPSHIQGNITPHAIVILPKTDGMEMLVCYED
      1140      1150      1160      1170      1180      1190       

             1270      1280      1290      1300      1310      1320
pF1KA0 EGVYVNTYGRITKDVVLQWGEMPTSVAYIHSNQIMGWGEKAIEIRSVETGHLDGVFMHKR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 EGVYVNTYGRITKDVVLQWGEMPTSVAYIHSNQIMGWGEKAIEIRSVETGHLDGVFMHKR
      1200      1210      1220      1230      1240      1250       

             1330      1340      1350      1360
pF1KA0 AQRLKFLCERNDKVFFASVRSGGSSQVFFMTLNRNSMMNW
       ::::::::::::::::::::::::::::::::::::::::
CCDS54 AQRLKFLCERNDKVFFASVRSGGSSQVFFMTLNRNSMMNW
      1260      1270      1280      1290       

>>CCDS74546.1 MAP4K4 gene_id:9448|Hs108|chr2              (1273 aa)
 initn: 4503 init1: 2092 opt: 2908  Z-score: 1118.2  bits: 219.2 E(32554): 5.8e-56
Smith-Waterman score: 5478; 64.7% identity (77.3% similar) in 1399 aa overlap (1-1360:1-1273)

               10        20        30        40        50        60
pF1KA0 MASDSPARSLDEIDLSALRDPAGIFELVELVGNGTYGQVYKGRHVKTGQLAAIKVMDVTG
       ::.::::.:: .::::.::::::::::::.::::::::::::::::::::::::::::: 
CCDS74 MANDSPAKSLVDIDLSSLRDPAGIFELVEVVGNGTYGQVYKGRHVKTGQLAAIKVMDVTE
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KA0 DEEEEIKQEINMLKKYSHHRNIATYYGAFIKKNPPGMDDQLWLVMEFCGAGSVTDLIKNT
       ::::::: ::::::::::::::::::::::::.::: :::::::::::::::.:::.:::
CCDS74 DEEEEIKLEINMLKKYSHHRNIATYYGAFIKKSPPGHDDQLWLVMEFCGAGSITDLVKNT
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KA0 KGNTLKEEWIAYICREILRGLSHLHQHKVIHRDIKGQNVLLTENAEVKLVDFGVSAQLDR
       :::::::.::::: :::::::.::: :.::::::::::::::::::::::::::::::::
CCDS74 KGNTLKEDWIAYISREILRGLAHLHIHHVIHRDIKGQNVLLTENAEVKLVDFGVSAQLDR
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KA0 TVGRRNTFIGTPYWMAPEVIACDENPDATYDFKSDLWSLGITAIEMAEGAPPLCDMHPMR
       :::::::::::::::::::::::::::::::..::::: :::::::::::::::::::::
CCDS74 TVGRRNTFIGTPYWMAPEVIACDENPDATYDYRSDLWSCGITAIEMAEGAPPLCDMHPMR
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KA0 ALFLIPRNPAPRLKSKKWSKKFQSFIESCLVKNHSQRPATEQLMKHPFIRDQPNERQVRI
       ::::::::: :::::::::::: ::::.:::::. :::.::::.::::::::::::::::
CCDS74 ALFLIPRNPPPRLKSKKWSKKFFSFIEGCLVKNYMQRPSTEQLLKHPFIRDQPNERQVRI
              250       260       270       280       290       300

              310       320       330         340       350        
pF1KA0 QLKDHIDRTKKKRGEKDETEYEYSGSEEEEEE--NDSGEPSSILNLPGESTLRRDFLRLQ
       :::::::::.::::::::::::::::::::::  .. ::::::.:.::::::::::::::
CCDS74 QLKDHIDRTRKKRGEKDETEYEYSGSEEEEEEVPEQEGEPSSIVNVPGESTLRRDFLRLQ
              310       320       330       340       350       360

      360       370         380       390       400       410      
pF1KA0 LANKERSEALRRQQL--EQQQRENEEHKRQLLAERQKRIEEQKEQRRRLEEQQRREKELR
         :::::::::::::  ::: ::.::.:::::::::::::.:::::::::::::::.: :
CCDS74 QENKERSEALRRQQLLQEQQLREQEEYKRQLLAERQKRIEQQKEQRRRLEEQQRREREAR
              370       380       390       400       410       420

        420       430                        440       450         
pF1KA0 KQQEREQRRHYEEQMRR-----------------EEERRRAEHEQEYIRRQLEEEQRQLE
       .::::::::. .:. ::                 :::.::.:.::::::::::::::.::
CCDS74 RQQEREQRRREQEEKRRLEELERRRKEEEERRRAEEEKRRVEREQEYIRRQLEEEQRHLE
              430       440       450       460       470       480

     460       470       480       490       500       510         
pF1KA0 ILQQQLLHEQALLLEYKRKQLEEQRQAERLQRQLKQERDYLVSLQHQRQEQRPVEK--KP
       .::::::.:::.::. .:.                         ::..:   : ..  ::
CCDS74 VLQQQLLQEQAMLLHDHRRPHP----------------------QHSQQPPPPQQERSKP
              490       500                             510        

       520       530       540       550       560       570       
pF1KA0 LYHYKEGMSPSEKPAWAKEVEERSRLNRQSSPAMPHKVANRISDPNLPPRSESFSISGVQ
        .:  :  .  :    :.:::.: : . .:::    : ..:. .: .: :::::: .: .
CCDS74 SFHAPEPKAHYEPADRAREVEDRFRKTNHSSPEAQSKQTGRVLEPPVPSRSESFS-NGNS
      520       530       540       550       560       570        

       580       590       600       610       620       630       
pF1KA0 PARTPPMLRPVDPQIPHLVAVKSQGPALTASQSVHEQPTKGLSGFQEALNVTSHRVEMPR
        .  : . ::..::.:  : . :..:.:.  .:    : .: ::               .
CCDS74 ESVHPALQRPAEPQVP--VRTTSRSPVLSRRDS----PLQG-SG---------------Q
       580       590         600           610                     

       640       650       660       670       680       690       
pF1KA0 QNSDPTSENPPLPTRIEKFDRSSWLRQEEDIPPKVPQRTTSISPALARKNSPGNGSALGP
       :::.  ..:    . ::   :  : : :. .:                   ::.::    
CCDS74 QNSQAGQRNS--TSSIEP--RLLWERVEKLVP------------------RPGSGS----
         620         630         640                               

       700       710       720       730       740       750       
pF1KA0 RLGSQPIRASNPDLRRTEPILESPLQRTSSGSSSSSSTPSSQPSSQGGSQPGSQAGSSER
                                   :::::.:.: :        ::.::::.::.::
CCDS74 ----------------------------SSGSSNSGSQP--------GSHPGSQSGSGER
                                 650       660               670   

       760       770       780       790       800       810       
pF1KA0 TRVRANSKSEGSPVLPHEPAKVKPEESRDITRPSRPASYKKAIDEDLTALAKELRELRIE
        :::..:::::::    : :  :::..... :: .::        :::::::::: .   
CCDS74 FRVRSSSKSEGSPSQRLENAVKKPEDKKEVFRPLKPA--------DLTALAKELRAV---
           680       690       700       710               720     

       820       830       840       850       860       870       
pF1KA0 ETNRPMKKVTDYSSSSEESESSEEEEEDGESETHDGTVAVSDIPRLIPTGAPGSNEQYNV
       :  :: .:::::::::::: ...::..: :.:  : ...  .  :   .   ...:  .:
CCDS74 EDVRPPHKVTDYSSSSEESGTTDEEDDDVEQEGADESTSGPEDTRAASSLNLSNGETESV
            730       740       750       760       770       780  

       880        890       900       910       920        930     
pF1KA0 GMVGTHG-LETSHADSFSGSISREGTLMIRETSGEKKRSGHSDSNGFAGHINL-PDLVQQ
         . .:  .:.  :     . :.::::..:... ..::..: .::::::.:.: :::.::
CCDS74 KTMIVHDDVESEPA----MTPSKEGTLIVRQSTVDQKRASHHESNGFAGRIHLLPDLLQQ
            790           800       810       820       830        

         940       950       960                     970       980 
pF1KA0 SHSPAGTPTEGLGRVSTHSQEMDSGT--------EYGMGSST------KASFTPFVDPRV
       ::: . . : .    :  .  :.  :        :   .:::      ..:::::.:::.
CCDS74 SHSSSTSSTSSSPSSSQPTPTMSPQTPQDKLTANETQSASSTLQKHKSSSSFTPFIDPRL
      840       850       860       870       880       890        

             990      1000      1010      1020      1030      1040 
pF1KA0 YQTSPTDEDEEDEESSAAALFTSELLRQEQAKLNEARKISVVNVNPTNIRPHSDTPEIRK
        : ::..        .... :. . .: :  . . .:: ::::::::: ::.::::::::
CCDS74 LQISPSS----GTTVTSVVGFSCDGMRPEAIRQDPTRKGSVVNVNPTNTRPQSDTPEIRK
      900           910       920       930       940       950    

            1050      1060      1070      1080      1090      1100 
pF1KA0 YKKRFNSEILCAALWGVNLLVGTENGLMLLDRSGQGKVYNLINRRRFQQMDVLEGLNVLV
       ::::::::::::::::::::::::.:::::::::::::: ::::::::::::::::::::
CCDS74 YKKRFNSEILCAALWGVNLLVGTESGLMLLDRSGQGKVYPLINRRRFQQMDVLEGLNVLV
          960       970       980       990      1000      1010    

            1110      1120      1130      1140      1150      1160 
pF1KA0 TISGKKNKLRVYYLSWLRNRILHNDPEVEKKQGWITVGDLEGCIHYKVVKYERIKFLVIA
       ::::::.::::::::::::.:::::::::::::: ::::::::.::::::::::::::::
CCDS74 TISGKKDKLRVYYLSWLRNKILHNDPEVEKKQGWTTVGDLEGCVHYKVVKYERIKFLVIA
         1020      1030      1040      1050      1060      1070    

            1170      1180      1190      1200      1210      1220 
pF1KA0 LKNAVEIYAWAPKPYHKFMAFKSFADLQHKPLLVDLTVEEGQRLKVIFGSHTGFHVIDVD
       ::..::.:::::::::::::::::..: :::::::::::::::::::.:: .:::..:::
CCDS74 LKSSVEVYAWAPKPYHKFMAFKSFGELVHKPLLVDLTVEEGQRLKVIYGSCAGFHAVDVD
         1080      1090      1100      1110      1120      1130    

            1230      1240      1250      1260      1270      1280 
pF1KA0 SGNSYDIYIPSHIQGNITPHAIVILPKTDGMEMLVCYEDEGVYVNTYGRITKDVVLQWGE
       ::. ::::.:.::: .: ::::.:::.:::::.:::::::::::::::::::::::::::
CCDS74 SGSVYDIYLPTHIQCSIKPHAIIILPNTDGMELLVCYEDEGVYVNTYGRITKDVVLQWGE
         1140      1150      1160      1170      1180      1190    

            1290      1300      1310      1320      1330      1340 
pF1KA0 MPTSVAYIHSNQIMGWGEKAIEIRSVETGHLDGVFMHKRAQRLKFLCERNDKVFFASVRS
       ::::::::.::: :::::::::::::::::::::::::::::::::::::::::::::::
CCDS74 MPTSVAYIRSNQTMGWGEKAIEIRSVETGHLDGVFMHKRAQRLKFLCERNDKVFFASVRS
         1200      1210      1220      1230      1240      1250    

            1350      1360
pF1KA0 GGSSQVFFMTLNRNSMMNW
       ::::::.::::.:.:...:
CCDS74 GGSSQVYFMTLGRTSLLSW
         1260      1270   

>>CCDS82487.1 MAP4K4 gene_id:9448|Hs108|chr2              (1165 aa)
 initn: 4514 init1: 2088 opt: 2791  Z-score: 1074.7  bits: 211.0 E(32554): 1.5e-53
Smith-Waterman score: 5041; 63.1% identity (74.2% similar) in 1380 aa overlap (1-1360:1-1165)

               10        20        30        40        50        60
pF1KA0 MASDSPARSLDEIDLSALRDPAGIFELVELVGNGTYGQVYKGRHVKTGQLAAIKVMDVTG
       ::.::::.:: .::::.::::::::::::.::::::::::::::::::::::::::::: 
CCDS82 MANDSPAKSLVDIDLSSLRDPAGIFELVEVVGNGTYGQVYKGRHVKTGQLAAIKVMDVTE
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KA0 DEEEEIKQEINMLKKYSHHRNIATYYGAFIKKNPPGMDDQLWLVMEFCGAGSVTDLIKNT
       ::::::: ::::::::::::::::::::::::.::: :::::::::::::::.:::.:::
CCDS82 DEEEEIKLEINMLKKYSHHRNIATYYGAFIKKSPPGHDDQLWLVMEFCGAGSITDLVKNT
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KA0 KGNTLKEEWIAYICREILRGLSHLHQHKVIHRDIKGQNVLLTENAEVKLVDFGVSAQLDR
       :::::::.::::: :::::::.::: :.::::::::::::::::::::::::::::::::
CCDS82 KGNTLKEDWIAYISREILRGLAHLHIHHVIHRDIKGQNVLLTENAEVKLVDFGVSAQLDR
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KA0 TVGRRNTFIGTPYWMAPEVIACDENPDATYDFKSDLWSLGITAIEMAEGAPPLCDMHPMR
       :::::::::::::::::::::::::::::::..::::: :::::::::::::::::::::
CCDS82 TVGRRNTFIGTPYWMAPEVIACDENPDATYDYRSDLWSCGITAIEMAEGAPPLCDMHPMR
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KA0 ALFLIPRNPAPRLKSKKWSKKFQSFIESCLVKNHSQRPATEQLMKHPFIRDQPNERQVRI
       ::::::::: :::::::::::: ::::.:::::. :::.::::.::::::::::::::::
CCDS82 ALFLIPRNPPPRLKSKKWSKKFFSFIEGCLVKNYMQRPSTEQLLKHPFIRDQPNERQVRI
              250       260       270       280       290       300

              310       320       330         340       350        
pF1KA0 QLKDHIDRTKKKRGEKDETEYEYSGSEEEEEE--NDSGEPSSILNLPGESTLRRDFLRLQ
       :::::::::.::::::::::::::::::::::  .. ::::::.:.::::::::::::::
CCDS82 QLKDHIDRTRKKRGEKDETEYEYSGSEEEEEEVPEQEGEPSSIVNVPGESTLRRDFLRLQ
              310       320       330       340       350       360

      360       370         380       390       400       410      
pF1KA0 LANKERSEALRRQQL--EQQQRENEEHKRQLLAERQKRIEEQKEQRRRLEEQQRREKELR
         :::::::::::::  ::: ::.::.:::::::::::::.:::::::::::::::.: :
CCDS82 QENKERSEALRRQQLLQEQQLREQEEYKRQLLAERQKRIEQQKEQRRRLEEQQRREREAR
              370       380       390       400       410       420

        420       430         440       450       460       470    
pF1KA0 KQQEREQRRHYEEQMRREEE--RRRAEHEQEYIRRQLEEEQRQLEILQQQLLHEQALLLE
       .::::::::. .:. :: ::  ::: :.:.   ::. :::.:..:       .::    :
CCDS82 RQQEREQRRREQEEKRRLEELERRRKEEEE---RRRAEEEKRRVE-------REQ----E
              430       440       450          460                 

          480        490       500       510       520       530   
pF1KA0 YKRKQLEE-QRQAERLQRQLKQERDYLVSLQHQRQEQRPVEKKPLYHYKEGMSPSEKPAW
       : :.:::: ::. : ::.:: ::. .:.  .:.:                          
CCDS82 YIRRQLEEEQRHLEVLQQQLLQEQAMLLH-DHRR--------------------------
        470       480       490                                    

           540       550       560       570       580       590   
pF1KA0 AKEVEERSRLNRQSSPAMPHKVANRISDPNLPPRSESFSISGVQPARTPPMLRPVDPQIP
                         ::           : .:.       ::   ::      ::  
CCDS82 ------------------PH-----------PQHSQ-------QP---PP------PQ--
                       500                            510          

           600       610       620       630       640       650   
pF1KA0 HLVAVKSQGPALTASQSVHEQPTKGLSGFQEALNVTSHRVEMPRQNSDPTSENPPLPTRI
                                    ::               : :. . :   .. 
CCDS82 -----------------------------QE--------------RSKPSFHAPEPKAHY
                                                       520         

           660       670       680       690       700       710   
pF1KA0 EKFDRSSWLRQEEDIPPKVPQRTTSISPALARKNSPGNGSALGPRLGSQPIRASNPDLRR
       :  ::.           .:: :::: ::.:.:..:: .::      :.:  .:.. .   
CCDS82 EPADRAR----------EVPVRTTSRSPVLSRRDSPLQGS------GQQNSQAGQRNSTS
     530                 540       550             560       570   

                720       730       740       750       760        
pF1KA0 TEPIL-----ESPLQRTSSGSSSSSSTPSSQPSSQGGSQPGSQAGSSERTRVRANSKSEG
        :: :     :. . : .:::::.::. .:::    ::.::::.::.:: :::..:::::
CCDS82 IEPRLLWERVEKLVPRPGSGSSSGSSNSGSQP----GSHPGSQSGSGERFRVRSSSKSEG
           580       590       600           610       620         

      770       780       790       800       810       820        
pF1KA0 SPVLPHEPAKVKPEESRDITRPSRPASYKKAIDEDLTALAKELRELRIEETNRPMKKVTD
       ::    : :  :::..... :: .::.     . :::::::::: .   :  :: .::::
CCDS82 SPSQRLENAVKKPEDKKEVFRPLKPAG-----EVDLTALAKELRAV---EDVRPPHKVTD
     630       640       650            660       670          680 

      830       840       850       860       870       880        
pF1KA0 YSSSSEESESSEEEEEDGESETHDGTVAVSDIPRLIPTGAPGSNEQYNVGMVGTHGLETS
       :::::::: ...::..: :.:                    :..:.       : : : .
CCDS82 YSSSSEESGTTDEEDDDVEQE--------------------GADES-------TSGPEDT
             690       700                                  710    

      890       900       910       920       930       940        
pF1KA0 HADSFSGSISREGTLMIRETSGEKKRSGHSDSNGFAGHINLPDLVQQSHSPAGTPTEGLG
       .: : : ..: .:     :: . :    :.: ..                :: ::..   
CCDS82 RAAS-SLNLS-NG-----ETESVKTMIVHDDVES---------------EPAMTPSKEGT
           720             730       740                      750  

      950       960       970       980       990      1000        
pF1KA0 RVSTHSQEMDSGTEYGMGSSTKASFTPFVDPRVYQTSPTDEDEEDEESSAAALFTSELLR
        .  ..:  .:  .   .::   :::::.:::. : ::..        .... :. . .:
CCDS82 LIVRQTQSASSTLQKHKSSS---SFTPFIDPRLLQISPSS----GTTVTSVVGFSCDGMR
            760       770          780           790       800     

     1010      1020      1030      1040      1050      1060        
pF1KA0 QEQAKLNEARKISVVNVNPTNIRPHSDTPEIRKYKKRFNSEILCAALWGVNLLVGTENGL
        :  . . .:: ::::::::: ::.::::::::::::::::::::::::::::::::.::
CCDS82 PEAIRQDPTRKGSVVNVNPTNTRPQSDTPEIRKYKKRFNSEILCAALWGVNLLVGTESGL
         810       820       830       840       850       860     

     1070      1080      1090      1100      1110      1120        
pF1KA0 MLLDRSGQGKVYNLINRRRFQQMDVLEGLNVLVTISGKKNKLRVYYLSWLRNRILHNDPE
       :::::::::::: ::::::::::::::::::::::::::.::::::::::::.:::::::
CCDS82 MLLDRSGQGKVYPLINRRRFQQMDVLEGLNVLVTISGKKDKLRVYYLSWLRNKILHNDPE
         870       880       890       900       910       920     

     1130      1140      1150      1160      1170      1180        
pF1KA0 VEKKQGWITVGDLEGCIHYKVVKYERIKFLVIALKNAVEIYAWAPKPYHKFMAFKSFADL
       ::::::: ::::::::.::::::::::::::::::..::.:::::::::::::::::..:
CCDS82 VEKKQGWTTVGDLEGCVHYKVVKYERIKFLVIALKSSVEVYAWAPKPYHKFMAFKSFGEL
         930       940       950       960       970       980     

     1190      1200      1210      1220      1230              1240
pF1KA0 QHKPLLVDLTVEEGQRLKVIFGSHTGFHVIDVDSGNSYDIYIPSHIQGN--------ITP
        :::::::::::::::::::.:: .:::..:::::. ::::.:.:.. :        : :
CCDS82 VHKPLLVDLTVEEGQRLKVIYGSCAGFHAVDVDSGSVYDIYLPTHVRKNPHSMIQCSIKP
         990      1000      1010      1020      1030      1040     

             1250      1260      1270      1280      1290      1300
pF1KA0 HAIVILPKTDGMEMLVCYEDEGVYVNTYGRITKDVVLQWGEMPTSVAYIHSNQIMGWGEK
       :::.:::.:::::.:::::::::::::::::::::::::::::::::::.::: ::::::
CCDS82 HAIIILPNTDGMELLVCYEDEGVYVNTYGRITKDVVLQWGEMPTSVAYIRSNQTMGWGEK
        1050      1060      1070      1080      1090      1100     

             1310      1320      1330      1340      1350      1360
pF1KA0 AIEIRSVETGHLDGVFMHKRAQRLKFLCERNDKVFFASVRSGGSSQVFFMTLNRNSMMNW
       :::::::::::::::::::::::::::::::::::::::::::::::.::::.:.:...:
CCDS82 AIEIRSVETGHLDGVFMHKRAQRLKFLCERNDKVFFASVRSGGSSQVYFMTLGRTSLLSW
        1110      1120      1130      1140      1150      1160     




1360 residues in 1 query   sequences
18511270 residues in 32554 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Thu Nov  3 09:41:26 2016 done: Thu Nov  3 09:41:27 2016
 Total Scan time:  6.530 Total Display time:  0.730

Function used was FASTA [36.3.4 Apr, 2011]
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