Result of FASTA (omim) for pF1KA0333
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KA0333, 1189 aa
  1>>>pF1KA0333 1189 - 1189 aa - 1189 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 11.1475+/-0.000419; mu= -4.3118+/- 0.026
 mean_var=330.4884+/-66.870, 0's: 0 Z-trim(121.1): 67  B-trim: 106 in 1/59
 Lambda= 0.070550
 statistics sampled from 37247 (37319) to 37247 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.746), E-opt: 0.2 (0.438), width:  16
 Scan time: 15.060

The best scores are:                                      opt bits E(85289)
NP_542987 (OMIM: 604140) death-inducer obliterator (1189) 7977 826.8       0
NP_001180299 (OMIM: 604140) death-inducer oblitera (1189) 7977 826.8       0
XP_011526811 (OMIM: 604140) PREDICTED: death-induc (2240) 7917 820.9       0
NP_001180298 (OMIM: 604140) death-inducer oblitera (2240) 7917 820.9       0
NP_149072 (OMIM: 604140) death-inducer obliterator (2240) 7917 820.9       0
XP_011526810 (OMIM: 604140) PREDICTED: death-induc (2276) 5276 552.1 1.5e-155
XP_011526807 (OMIM: 604140) PREDICTED: death-induc (2276) 5276 552.1 1.5e-155
XP_011526806 (OMIM: 604140) PREDICTED: death-induc (2276) 5276 552.1 1.5e-155
XP_011526809 (OMIM: 604140) PREDICTED: death-induc (2276) 5276 552.1 1.5e-155
XP_011526808 (OMIM: 604140) PREDICTED: death-induc (2276) 5276 552.1 1.5e-155
NP_071388 (OMIM: 604140) death-inducer obliterator ( 562) 3608 381.9 6.4e-105
NP_542986 (OMIM: 604140) death-inducer obliterator ( 562) 3608 381.9 6.4e-105
XP_005248760 (OMIM: 607789) PREDICTED: PHD finger  (1308)  644 80.4 8.1e-14
XP_016866115 (OMIM: 607789) PREDICTED: PHD finger  (1308)  644 80.4 8.1e-14
XP_005248759 (OMIM: 607789) PREDICTED: PHD finger  (1951)  644 80.6 1.1e-13
NP_001277188 (OMIM: 607789) PHD finger protein 3 i (1951)  644 80.6 1.1e-13
XP_006715489 (OMIM: 607789) PREDICTED: PHD finger  (2039)  644 80.6 1.1e-13
XP_005248758 (OMIM: 607789) PREDICTED: PHD finger  (2039)  644 80.6 1.1e-13
NP_055968 (OMIM: 607789) PHD finger protein 3 isof (2039)  644 80.6 1.1e-13
XP_011533950 (OMIM: 607789) PREDICTED: PHD finger  (2048)  644 80.6 1.2e-13


>>NP_542987 (OMIM: 604140) death-inducer obliterator 1 i  (1189 aa)
 initn: 7977 init1: 7977 opt: 7977  Z-score: 4403.3  bits: 826.8 E(85289):    0
Smith-Waterman score: 7977; 100.0% identity (100.0% similar) in 1189 aa overlap (1-1189:1-1189)

               10        20        30        40        50        60
pF1KA0 MDDKGDPSNEEAPKAIKPTSKEFRKTWGFRRTTIAKREGAGDAEADPLEPPPPQQQLGLS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_542 MDDKGDPSNEEAPKAIKPTSKEFRKTWGFRRTTIAKREGAGDAEADPLEPPPPQQQLGLS
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KA0 LRRSGRQPKRTERVEQFLTIARRRGRRSMPVSLEDSGEPTSCPATDAETASEGSVESASE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_542 LRRSGRQPKRTERVEQFLTIARRRGRRSMPVSLEDSGEPTSCPATDAETASEGSVESASE
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KA0 TRSGPQSASTAVKERPASSEKVKGGDDHDDTSDSDSDGLTLKELQNRLRRKREQEPTERP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_542 TRSGPQSASTAVKERPASSEKVKGGDDHDDTSDSDSDGLTLKELQNRLRRKREQEPTERP
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KA0 LKGIQSRLRKKRREEGPAETVGSEASDTVEGVLPSKQEPENDQGVVSQAGKDDRESKLEG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_542 LKGIQSRLRKKRREEGPAETVGSEASDTVEGVLPSKQEPENDQGVVSQAGKDDRESKLEG
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KA0 KAAQDIKDEEPGDLGRPKPECEGYDPNALYCICRQPHNNRFMICCDRCEEWFHGDCVGIS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_542 KAAQDIKDEEPGDLGRPKPECEGYDPNALYCICRQPHNNRFMICCDRCEEWFHGDCVGIS
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KA0 EARGRLLERNGEDYICPNCTILQVQDETHSETADQQEAKWRPGDADGTDCTSIGTIEQKS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_542 EARGRLLERNGEDYICPNCTILQVQDETHSETADQQEAKWRPGDADGTDCTSIGTIEQKS
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KA0 SEDQGIKGRIEKAANPSGKKKLKIFQPVIEAPGASKCIGPGCCHVAQPDSVYCSNDCILK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_542 SEDQGIKGRIEKAANPSGKKKLKIFQPVIEAPGASKCIGPGCCHVAQPDSVYCSNDCILK
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KA0 HAAATMKFLSSGKEQKPKPKEKMKMKPEKPSLPKCGAQAGIKISSVHKRPAPEKKETTVK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_542 HAAATMKFLSSGKEQKPKPKEKMKMKPEKPSLPKCGAQAGIKISSVHKRPAPEKKETTVK
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KA0 KAVVVPARSEALGKEAACESSTPSWASDHNYNAVKPEKTAAPSPSLLYKSTKEDRRSEEK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_542 KAVVVPARSEALGKEAACESSTPSWASDHNYNAVKPEKTAAPSPSLLYKSTKEDRRSEEK
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KA0 AAAMAASKKTAPPGSAVGKQPAPRNLVPKKSSFANVAAATPAIKKPPSGFKGTIPKRPWL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_542 AAAMAASKKTAPPGSAVGKQPAPRNLVPKKSSFANVAAATPAIKKPPSGFKGTIPKRPWL
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KA0 SATPSSGASAARQAGPAPAAATAASKKFPGSAALVGAVRKPVVPSVPMASPAPGRLGAMS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_542 SATPSSGASAARQAGPAPAAATAASKKFPGSAALVGAVRKPVVPSVPMASPAPGRLGAMS
              610       620       630       640       650       660

              670       680       690       700       710       720
pF1KA0 AAPSQPNSQIRQNIRRSLKEILWKRVNDSDDLIMTENEVGKIALHIEKEMFNLFQVTDNR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_542 AAPSQPNSQIRQNIRRSLKEILWKRVNDSDDLIMTENEVGKIALHIEKEMFNLFQVTDNR
              670       680       690       700       710       720

              730       740       750       760       770       780
pF1KA0 YKSKYRSIMFNLKDPKNQGLFHRVLREEISLAKLVRLKPEELVSKELSTWKERPARSVME
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_542 YKSKYRSIMFNLKDPKNQGLFHRVLREEISLAKLVRLKPEELVSKELSTWKERPARSVME
              730       740       750       760       770       780

              790       800       810       820       830       840
pF1KA0 SRTKLHNESKKTAPRQEAIPDLEDSPPVSDSEEQQESARAVPEKSTAPLLDVFSSMLKDT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_542 SRTKLHNESKKTAPRQEAIPDLEDSPPVSDSEEQQESARAVPEKSTAPLLDVFSSMLKDT
              790       800       810       820       830       840

              850       860       870       880       890       900
pF1KA0 TSQHRAHLFDLNCKICTGQVPSAEDEPAPKKQKLSASVKKEDLKSKHDSSAPDPAPDSAD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_542 TSQHRAHLFDLNCKICTGQVPSAEDEPAPKKQKLSASVKKEDLKSKHDSSAPDPAPDSAD
              850       860       870       880       890       900

              910       920       930       940       950       960
pF1KA0 EVMPEAVPEVASEPGLESASHPNVDRTYFPGPPGDGHPEPSPLEDLSPCPASCGSGVVTT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_542 EVMPEAVPEVASEPGLESASHPNVDRTYFPGPPGDGHPEPSPLEDLSPCPASCGSGVVTT
              910       920       930       940       950       960

              970       980       990      1000      1010      1020
pF1KA0 VTVSGRDPRTAPSSSCTAVASAASRPDSTHMVEARQDVPKPVLTSVMVPKSILAKPSSSP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_542 VTVSGRDPRTAPSSSCTAVASAASRPDSTHMVEARQDVPKPVLTSVMVPKSILAKPSSSP
              970       980       990      1000      1010      1020

             1030      1040      1050      1060      1070      1080
pF1KA0 DPRYLSVPPSPNISTSESRSPPEGDTTLFLSRLSTIWKGFINMQSVAKFVTKAYPVSGCF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_542 DPRYLSVPPSPNISTSESRSPPEGDTTLFLSRLSTIWKGFINMQSVAKFVTKAYPVSGCF
             1030      1040      1050      1060      1070      1080

             1090      1100      1110      1120      1130      1140
pF1KA0 DYLSEDLPDTIHIGGRIAPKTVWDYVGKLKSSVSKELCLIRFHPATEEEEVAYISLYSYF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_542 DYLSEDLPDTIHIGGRIAPKTVWDYVGKLKSSVSKELCLIRFHPATEEEEVAYISLYSYF
             1090      1100      1110      1120      1130      1140

             1150      1160      1170      1180         
pF1KA0 SSRGRFGVVANNNRHVKDLYLIPLSAQDPVPSKLLPFEGPGKRRLSGWR
       :::::::::::::::::::::::::::::::::::::::::::::::::
NP_542 SSRGRFGVVANNNRHVKDLYLIPLSAQDPVPSKLLPFEGPGKRRLSGWR
             1150      1160      1170      1180         

>>NP_001180299 (OMIM: 604140) death-inducer obliterator   (1189 aa)
 initn: 7977 init1: 7977 opt: 7977  Z-score: 4403.3  bits: 826.8 E(85289):    0
Smith-Waterman score: 7977; 100.0% identity (100.0% similar) in 1189 aa overlap (1-1189:1-1189)

               10        20        30        40        50        60
pF1KA0 MDDKGDPSNEEAPKAIKPTSKEFRKTWGFRRTTIAKREGAGDAEADPLEPPPPQQQLGLS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MDDKGDPSNEEAPKAIKPTSKEFRKTWGFRRTTIAKREGAGDAEADPLEPPPPQQQLGLS
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KA0 LRRSGRQPKRTERVEQFLTIARRRGRRSMPVSLEDSGEPTSCPATDAETASEGSVESASE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LRRSGRQPKRTERVEQFLTIARRRGRRSMPVSLEDSGEPTSCPATDAETASEGSVESASE
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KA0 TRSGPQSASTAVKERPASSEKVKGGDDHDDTSDSDSDGLTLKELQNRLRRKREQEPTERP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TRSGPQSASTAVKERPASSEKVKGGDDHDDTSDSDSDGLTLKELQNRLRRKREQEPTERP
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KA0 LKGIQSRLRKKRREEGPAETVGSEASDTVEGVLPSKQEPENDQGVVSQAGKDDRESKLEG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LKGIQSRLRKKRREEGPAETVGSEASDTVEGVLPSKQEPENDQGVVSQAGKDDRESKLEG
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KA0 KAAQDIKDEEPGDLGRPKPECEGYDPNALYCICRQPHNNRFMICCDRCEEWFHGDCVGIS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KAAQDIKDEEPGDLGRPKPECEGYDPNALYCICRQPHNNRFMICCDRCEEWFHGDCVGIS
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KA0 EARGRLLERNGEDYICPNCTILQVQDETHSETADQQEAKWRPGDADGTDCTSIGTIEQKS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EARGRLLERNGEDYICPNCTILQVQDETHSETADQQEAKWRPGDADGTDCTSIGTIEQKS
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KA0 SEDQGIKGRIEKAANPSGKKKLKIFQPVIEAPGASKCIGPGCCHVAQPDSVYCSNDCILK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SEDQGIKGRIEKAANPSGKKKLKIFQPVIEAPGASKCIGPGCCHVAQPDSVYCSNDCILK
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KA0 HAAATMKFLSSGKEQKPKPKEKMKMKPEKPSLPKCGAQAGIKISSVHKRPAPEKKETTVK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HAAATMKFLSSGKEQKPKPKEKMKMKPEKPSLPKCGAQAGIKISSVHKRPAPEKKETTVK
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KA0 KAVVVPARSEALGKEAACESSTPSWASDHNYNAVKPEKTAAPSPSLLYKSTKEDRRSEEK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KAVVVPARSEALGKEAACESSTPSWASDHNYNAVKPEKTAAPSPSLLYKSTKEDRRSEEK
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KA0 AAAMAASKKTAPPGSAVGKQPAPRNLVPKKSSFANVAAATPAIKKPPSGFKGTIPKRPWL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AAAMAASKKTAPPGSAVGKQPAPRNLVPKKSSFANVAAATPAIKKPPSGFKGTIPKRPWL
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KA0 SATPSSGASAARQAGPAPAAATAASKKFPGSAALVGAVRKPVVPSVPMASPAPGRLGAMS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SATPSSGASAARQAGPAPAAATAASKKFPGSAALVGAVRKPVVPSVPMASPAPGRLGAMS
              610       620       630       640       650       660

              670       680       690       700       710       720
pF1KA0 AAPSQPNSQIRQNIRRSLKEILWKRVNDSDDLIMTENEVGKIALHIEKEMFNLFQVTDNR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AAPSQPNSQIRQNIRRSLKEILWKRVNDSDDLIMTENEVGKIALHIEKEMFNLFQVTDNR
              670       680       690       700       710       720

              730       740       750       760       770       780
pF1KA0 YKSKYRSIMFNLKDPKNQGLFHRVLREEISLAKLVRLKPEELVSKELSTWKERPARSVME
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YKSKYRSIMFNLKDPKNQGLFHRVLREEISLAKLVRLKPEELVSKELSTWKERPARSVME
              730       740       750       760       770       780

              790       800       810       820       830       840
pF1KA0 SRTKLHNESKKTAPRQEAIPDLEDSPPVSDSEEQQESARAVPEKSTAPLLDVFSSMLKDT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SRTKLHNESKKTAPRQEAIPDLEDSPPVSDSEEQQESARAVPEKSTAPLLDVFSSMLKDT
              790       800       810       820       830       840

              850       860       870       880       890       900
pF1KA0 TSQHRAHLFDLNCKICTGQVPSAEDEPAPKKQKLSASVKKEDLKSKHDSSAPDPAPDSAD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TSQHRAHLFDLNCKICTGQVPSAEDEPAPKKQKLSASVKKEDLKSKHDSSAPDPAPDSAD
              850       860       870       880       890       900

              910       920       930       940       950       960
pF1KA0 EVMPEAVPEVASEPGLESASHPNVDRTYFPGPPGDGHPEPSPLEDLSPCPASCGSGVVTT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EVMPEAVPEVASEPGLESASHPNVDRTYFPGPPGDGHPEPSPLEDLSPCPASCGSGVVTT
              910       920       930       940       950       960

              970       980       990      1000      1010      1020
pF1KA0 VTVSGRDPRTAPSSSCTAVASAASRPDSTHMVEARQDVPKPVLTSVMVPKSILAKPSSSP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VTVSGRDPRTAPSSSCTAVASAASRPDSTHMVEARQDVPKPVLTSVMVPKSILAKPSSSP
              970       980       990      1000      1010      1020

             1030      1040      1050      1060      1070      1080
pF1KA0 DPRYLSVPPSPNISTSESRSPPEGDTTLFLSRLSTIWKGFINMQSVAKFVTKAYPVSGCF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DPRYLSVPPSPNISTSESRSPPEGDTTLFLSRLSTIWKGFINMQSVAKFVTKAYPVSGCF
             1030      1040      1050      1060      1070      1080

             1090      1100      1110      1120      1130      1140
pF1KA0 DYLSEDLPDTIHIGGRIAPKTVWDYVGKLKSSVSKELCLIRFHPATEEEEVAYISLYSYF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DYLSEDLPDTIHIGGRIAPKTVWDYVGKLKSSVSKELCLIRFHPATEEEEVAYISLYSYF
             1090      1100      1110      1120      1130      1140

             1150      1160      1170      1180         
pF1KA0 SSRGRFGVVANNNRHVKDLYLIPLSAQDPVPSKLLPFEGPGKRRLSGWR
       :::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SSRGRFGVVANNNRHVKDLYLIPLSAQDPVPSKLLPFEGPGKRRLSGWR
             1150      1160      1170      1180         

>>XP_011526811 (OMIM: 604140) PREDICTED: death-inducer o  (2240 aa)
 initn: 7917 init1: 7917 opt: 7917  Z-score: 4366.5  bits: 820.9 E(85289):    0
Smith-Waterman score: 7917; 100.0% identity (100.0% similar) in 1181 aa overlap (1-1181:1-1181)

               10        20        30        40        50        60
pF1KA0 MDDKGDPSNEEAPKAIKPTSKEFRKTWGFRRTTIAKREGAGDAEADPLEPPPPQQQLGLS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MDDKGDPSNEEAPKAIKPTSKEFRKTWGFRRTTIAKREGAGDAEADPLEPPPPQQQLGLS
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KA0 LRRSGRQPKRTERVEQFLTIARRRGRRSMPVSLEDSGEPTSCPATDAETASEGSVESASE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LRRSGRQPKRTERVEQFLTIARRRGRRSMPVSLEDSGEPTSCPATDAETASEGSVESASE
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KA0 TRSGPQSASTAVKERPASSEKVKGGDDHDDTSDSDSDGLTLKELQNRLRRKREQEPTERP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TRSGPQSASTAVKERPASSEKVKGGDDHDDTSDSDSDGLTLKELQNRLRRKREQEPTERP
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KA0 LKGIQSRLRKKRREEGPAETVGSEASDTVEGVLPSKQEPENDQGVVSQAGKDDRESKLEG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LKGIQSRLRKKRREEGPAETVGSEASDTVEGVLPSKQEPENDQGVVSQAGKDDRESKLEG
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KA0 KAAQDIKDEEPGDLGRPKPECEGYDPNALYCICRQPHNNRFMICCDRCEEWFHGDCVGIS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KAAQDIKDEEPGDLGRPKPECEGYDPNALYCICRQPHNNRFMICCDRCEEWFHGDCVGIS
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KA0 EARGRLLERNGEDYICPNCTILQVQDETHSETADQQEAKWRPGDADGTDCTSIGTIEQKS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EARGRLLERNGEDYICPNCTILQVQDETHSETADQQEAKWRPGDADGTDCTSIGTIEQKS
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KA0 SEDQGIKGRIEKAANPSGKKKLKIFQPVIEAPGASKCIGPGCCHVAQPDSVYCSNDCILK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SEDQGIKGRIEKAANPSGKKKLKIFQPVIEAPGASKCIGPGCCHVAQPDSVYCSNDCILK
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KA0 HAAATMKFLSSGKEQKPKPKEKMKMKPEKPSLPKCGAQAGIKISSVHKRPAPEKKETTVK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HAAATMKFLSSGKEQKPKPKEKMKMKPEKPSLPKCGAQAGIKISSVHKRPAPEKKETTVK
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KA0 KAVVVPARSEALGKEAACESSTPSWASDHNYNAVKPEKTAAPSPSLLYKSTKEDRRSEEK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KAVVVPARSEALGKEAACESSTPSWASDHNYNAVKPEKTAAPSPSLLYKSTKEDRRSEEK
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KA0 AAAMAASKKTAPPGSAVGKQPAPRNLVPKKSSFANVAAATPAIKKPPSGFKGTIPKRPWL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AAAMAASKKTAPPGSAVGKQPAPRNLVPKKSSFANVAAATPAIKKPPSGFKGTIPKRPWL
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KA0 SATPSSGASAARQAGPAPAAATAASKKFPGSAALVGAVRKPVVPSVPMASPAPGRLGAMS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SATPSSGASAARQAGPAPAAATAASKKFPGSAALVGAVRKPVVPSVPMASPAPGRLGAMS
              610       620       630       640       650       660

              670       680       690       700       710       720
pF1KA0 AAPSQPNSQIRQNIRRSLKEILWKRVNDSDDLIMTENEVGKIALHIEKEMFNLFQVTDNR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AAPSQPNSQIRQNIRRSLKEILWKRVNDSDDLIMTENEVGKIALHIEKEMFNLFQVTDNR
              670       680       690       700       710       720

              730       740       750       760       770       780
pF1KA0 YKSKYRSIMFNLKDPKNQGLFHRVLREEISLAKLVRLKPEELVSKELSTWKERPARSVME
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YKSKYRSIMFNLKDPKNQGLFHRVLREEISLAKLVRLKPEELVSKELSTWKERPARSVME
              730       740       750       760       770       780

              790       800       810       820       830       840
pF1KA0 SRTKLHNESKKTAPRQEAIPDLEDSPPVSDSEEQQESARAVPEKSTAPLLDVFSSMLKDT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SRTKLHNESKKTAPRQEAIPDLEDSPPVSDSEEQQESARAVPEKSTAPLLDVFSSMLKDT
              790       800       810       820       830       840

              850       860       870       880       890       900
pF1KA0 TSQHRAHLFDLNCKICTGQVPSAEDEPAPKKQKLSASVKKEDLKSKHDSSAPDPAPDSAD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TSQHRAHLFDLNCKICTGQVPSAEDEPAPKKQKLSASVKKEDLKSKHDSSAPDPAPDSAD
              850       860       870       880       890       900

              910       920       930       940       950       960
pF1KA0 EVMPEAVPEVASEPGLESASHPNVDRTYFPGPPGDGHPEPSPLEDLSPCPASCGSGVVTT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EVMPEAVPEVASEPGLESASHPNVDRTYFPGPPGDGHPEPSPLEDLSPCPASCGSGVVTT
              910       920       930       940       950       960

              970       980       990      1000      1010      1020
pF1KA0 VTVSGRDPRTAPSSSCTAVASAASRPDSTHMVEARQDVPKPVLTSVMVPKSILAKPSSSP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VTVSGRDPRTAPSSSCTAVASAASRPDSTHMVEARQDVPKPVLTSVMVPKSILAKPSSSP
              970       980       990      1000      1010      1020

             1030      1040      1050      1060      1070      1080
pF1KA0 DPRYLSVPPSPNISTSESRSPPEGDTTLFLSRLSTIWKGFINMQSVAKFVTKAYPVSGCF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DPRYLSVPPSPNISTSESRSPPEGDTTLFLSRLSTIWKGFINMQSVAKFVTKAYPVSGCF
             1030      1040      1050      1060      1070      1080

             1090      1100      1110      1120      1130      1140
pF1KA0 DYLSEDLPDTIHIGGRIAPKTVWDYVGKLKSSVSKELCLIRFHPATEEEEVAYISLYSYF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DYLSEDLPDTIHIGGRIAPKTVWDYVGKLKSSVSKELCLIRFHPATEEEEVAYISLYSYF
             1090      1100      1110      1120      1130      1140

             1150      1160      1170      1180                    
pF1KA0 SSRGRFGVVANNNRHVKDLYLIPLSAQDPVPSKLLPFEGPGKRRLSGWR           
       :::::::::::::::::::::::::::::::::::::::::                   
XP_011 SSRGRFGVVANNNRHVKDLYLIPLSAQDPVPSKLLPFEGPGLESPRPNIILGLVICQKIK
             1150      1160      1170      1180      1190      1200

XP_011 RPANSGELDKMDEKRTRLQPEEADVPAYPKVATVPQSEKKPSKYPLCSADAAVSTTPPGS
             1210      1220      1230      1240      1250      1260

>>NP_001180298 (OMIM: 604140) death-inducer obliterator   (2240 aa)
 initn: 7917 init1: 7917 opt: 7917  Z-score: 4366.5  bits: 820.9 E(85289):    0
Smith-Waterman score: 7917; 100.0% identity (100.0% similar) in 1181 aa overlap (1-1181:1-1181)

               10        20        30        40        50        60
pF1KA0 MDDKGDPSNEEAPKAIKPTSKEFRKTWGFRRTTIAKREGAGDAEADPLEPPPPQQQLGLS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MDDKGDPSNEEAPKAIKPTSKEFRKTWGFRRTTIAKREGAGDAEADPLEPPPPQQQLGLS
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KA0 LRRSGRQPKRTERVEQFLTIARRRGRRSMPVSLEDSGEPTSCPATDAETASEGSVESASE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LRRSGRQPKRTERVEQFLTIARRRGRRSMPVSLEDSGEPTSCPATDAETASEGSVESASE
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KA0 TRSGPQSASTAVKERPASSEKVKGGDDHDDTSDSDSDGLTLKELQNRLRRKREQEPTERP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TRSGPQSASTAVKERPASSEKVKGGDDHDDTSDSDSDGLTLKELQNRLRRKREQEPTERP
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KA0 LKGIQSRLRKKRREEGPAETVGSEASDTVEGVLPSKQEPENDQGVVSQAGKDDRESKLEG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LKGIQSRLRKKRREEGPAETVGSEASDTVEGVLPSKQEPENDQGVVSQAGKDDRESKLEG
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KA0 KAAQDIKDEEPGDLGRPKPECEGYDPNALYCICRQPHNNRFMICCDRCEEWFHGDCVGIS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KAAQDIKDEEPGDLGRPKPECEGYDPNALYCICRQPHNNRFMICCDRCEEWFHGDCVGIS
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KA0 EARGRLLERNGEDYICPNCTILQVQDETHSETADQQEAKWRPGDADGTDCTSIGTIEQKS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EARGRLLERNGEDYICPNCTILQVQDETHSETADQQEAKWRPGDADGTDCTSIGTIEQKS
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KA0 SEDQGIKGRIEKAANPSGKKKLKIFQPVIEAPGASKCIGPGCCHVAQPDSVYCSNDCILK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SEDQGIKGRIEKAANPSGKKKLKIFQPVIEAPGASKCIGPGCCHVAQPDSVYCSNDCILK
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KA0 HAAATMKFLSSGKEQKPKPKEKMKMKPEKPSLPKCGAQAGIKISSVHKRPAPEKKETTVK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HAAATMKFLSSGKEQKPKPKEKMKMKPEKPSLPKCGAQAGIKISSVHKRPAPEKKETTVK
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KA0 KAVVVPARSEALGKEAACESSTPSWASDHNYNAVKPEKTAAPSPSLLYKSTKEDRRSEEK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KAVVVPARSEALGKEAACESSTPSWASDHNYNAVKPEKTAAPSPSLLYKSTKEDRRSEEK
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KA0 AAAMAASKKTAPPGSAVGKQPAPRNLVPKKSSFANVAAATPAIKKPPSGFKGTIPKRPWL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AAAMAASKKTAPPGSAVGKQPAPRNLVPKKSSFANVAAATPAIKKPPSGFKGTIPKRPWL
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KA0 SATPSSGASAARQAGPAPAAATAASKKFPGSAALVGAVRKPVVPSVPMASPAPGRLGAMS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SATPSSGASAARQAGPAPAAATAASKKFPGSAALVGAVRKPVVPSVPMASPAPGRLGAMS
              610       620       630       640       650       660

              670       680       690       700       710       720
pF1KA0 AAPSQPNSQIRQNIRRSLKEILWKRVNDSDDLIMTENEVGKIALHIEKEMFNLFQVTDNR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AAPSQPNSQIRQNIRRSLKEILWKRVNDSDDLIMTENEVGKIALHIEKEMFNLFQVTDNR
              670       680       690       700       710       720

              730       740       750       760       770       780
pF1KA0 YKSKYRSIMFNLKDPKNQGLFHRVLREEISLAKLVRLKPEELVSKELSTWKERPARSVME
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YKSKYRSIMFNLKDPKNQGLFHRVLREEISLAKLVRLKPEELVSKELSTWKERPARSVME
              730       740       750       760       770       780

              790       800       810       820       830       840
pF1KA0 SRTKLHNESKKTAPRQEAIPDLEDSPPVSDSEEQQESARAVPEKSTAPLLDVFSSMLKDT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SRTKLHNESKKTAPRQEAIPDLEDSPPVSDSEEQQESARAVPEKSTAPLLDVFSSMLKDT
              790       800       810       820       830       840

              850       860       870       880       890       900
pF1KA0 TSQHRAHLFDLNCKICTGQVPSAEDEPAPKKQKLSASVKKEDLKSKHDSSAPDPAPDSAD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TSQHRAHLFDLNCKICTGQVPSAEDEPAPKKQKLSASVKKEDLKSKHDSSAPDPAPDSAD
              850       860       870       880       890       900

              910       920       930       940       950       960
pF1KA0 EVMPEAVPEVASEPGLESASHPNVDRTYFPGPPGDGHPEPSPLEDLSPCPASCGSGVVTT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EVMPEAVPEVASEPGLESASHPNVDRTYFPGPPGDGHPEPSPLEDLSPCPASCGSGVVTT
              910       920       930       940       950       960

              970       980       990      1000      1010      1020
pF1KA0 VTVSGRDPRTAPSSSCTAVASAASRPDSTHMVEARQDVPKPVLTSVMVPKSILAKPSSSP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VTVSGRDPRTAPSSSCTAVASAASRPDSTHMVEARQDVPKPVLTSVMVPKSILAKPSSSP
              970       980       990      1000      1010      1020

             1030      1040      1050      1060      1070      1080
pF1KA0 DPRYLSVPPSPNISTSESRSPPEGDTTLFLSRLSTIWKGFINMQSVAKFVTKAYPVSGCF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DPRYLSVPPSPNISTSESRSPPEGDTTLFLSRLSTIWKGFINMQSVAKFVTKAYPVSGCF
             1030      1040      1050      1060      1070      1080

             1090      1100      1110      1120      1130      1140
pF1KA0 DYLSEDLPDTIHIGGRIAPKTVWDYVGKLKSSVSKELCLIRFHPATEEEEVAYISLYSYF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DYLSEDLPDTIHIGGRIAPKTVWDYVGKLKSSVSKELCLIRFHPATEEEEVAYISLYSYF
             1090      1100      1110      1120      1130      1140

             1150      1160      1170      1180                    
pF1KA0 SSRGRFGVVANNNRHVKDLYLIPLSAQDPVPSKLLPFEGPGKRRLSGWR           
       :::::::::::::::::::::::::::::::::::::::::                   
NP_001 SSRGRFGVVANNNRHVKDLYLIPLSAQDPVPSKLLPFEGPGLESPRPNIILGLVICQKIK
             1150      1160      1170      1180      1190      1200

NP_001 RPANSGELDKMDEKRTRLQPEEADVPAYPKVATVPQSEKKPSKYPLCSADAAVSTTPPGS
             1210      1220      1230      1240      1250      1260

>>NP_149072 (OMIM: 604140) death-inducer obliterator 1 i  (2240 aa)
 initn: 7917 init1: 7917 opt: 7917  Z-score: 4366.5  bits: 820.9 E(85289):    0
Smith-Waterman score: 7917; 100.0% identity (100.0% similar) in 1181 aa overlap (1-1181:1-1181)

               10        20        30        40        50        60
pF1KA0 MDDKGDPSNEEAPKAIKPTSKEFRKTWGFRRTTIAKREGAGDAEADPLEPPPPQQQLGLS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_149 MDDKGDPSNEEAPKAIKPTSKEFRKTWGFRRTTIAKREGAGDAEADPLEPPPPQQQLGLS
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KA0 LRRSGRQPKRTERVEQFLTIARRRGRRSMPVSLEDSGEPTSCPATDAETASEGSVESASE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_149 LRRSGRQPKRTERVEQFLTIARRRGRRSMPVSLEDSGEPTSCPATDAETASEGSVESASE
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KA0 TRSGPQSASTAVKERPASSEKVKGGDDHDDTSDSDSDGLTLKELQNRLRRKREQEPTERP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_149 TRSGPQSASTAVKERPASSEKVKGGDDHDDTSDSDSDGLTLKELQNRLRRKREQEPTERP
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KA0 LKGIQSRLRKKRREEGPAETVGSEASDTVEGVLPSKQEPENDQGVVSQAGKDDRESKLEG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_149 LKGIQSRLRKKRREEGPAETVGSEASDTVEGVLPSKQEPENDQGVVSQAGKDDRESKLEG
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KA0 KAAQDIKDEEPGDLGRPKPECEGYDPNALYCICRQPHNNRFMICCDRCEEWFHGDCVGIS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_149 KAAQDIKDEEPGDLGRPKPECEGYDPNALYCICRQPHNNRFMICCDRCEEWFHGDCVGIS
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KA0 EARGRLLERNGEDYICPNCTILQVQDETHSETADQQEAKWRPGDADGTDCTSIGTIEQKS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_149 EARGRLLERNGEDYICPNCTILQVQDETHSETADQQEAKWRPGDADGTDCTSIGTIEQKS
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KA0 SEDQGIKGRIEKAANPSGKKKLKIFQPVIEAPGASKCIGPGCCHVAQPDSVYCSNDCILK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_149 SEDQGIKGRIEKAANPSGKKKLKIFQPVIEAPGASKCIGPGCCHVAQPDSVYCSNDCILK
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KA0 HAAATMKFLSSGKEQKPKPKEKMKMKPEKPSLPKCGAQAGIKISSVHKRPAPEKKETTVK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_149 HAAATMKFLSSGKEQKPKPKEKMKMKPEKPSLPKCGAQAGIKISSVHKRPAPEKKETTVK
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KA0 KAVVVPARSEALGKEAACESSTPSWASDHNYNAVKPEKTAAPSPSLLYKSTKEDRRSEEK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_149 KAVVVPARSEALGKEAACESSTPSWASDHNYNAVKPEKTAAPSPSLLYKSTKEDRRSEEK
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KA0 AAAMAASKKTAPPGSAVGKQPAPRNLVPKKSSFANVAAATPAIKKPPSGFKGTIPKRPWL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_149 AAAMAASKKTAPPGSAVGKQPAPRNLVPKKSSFANVAAATPAIKKPPSGFKGTIPKRPWL
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KA0 SATPSSGASAARQAGPAPAAATAASKKFPGSAALVGAVRKPVVPSVPMASPAPGRLGAMS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_149 SATPSSGASAARQAGPAPAAATAASKKFPGSAALVGAVRKPVVPSVPMASPAPGRLGAMS
              610       620       630       640       650       660

              670       680       690       700       710       720
pF1KA0 AAPSQPNSQIRQNIRRSLKEILWKRVNDSDDLIMTENEVGKIALHIEKEMFNLFQVTDNR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_149 AAPSQPNSQIRQNIRRSLKEILWKRVNDSDDLIMTENEVGKIALHIEKEMFNLFQVTDNR
              670       680       690       700       710       720

              730       740       750       760       770       780
pF1KA0 YKSKYRSIMFNLKDPKNQGLFHRVLREEISLAKLVRLKPEELVSKELSTWKERPARSVME
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_149 YKSKYRSIMFNLKDPKNQGLFHRVLREEISLAKLVRLKPEELVSKELSTWKERPARSVME
              730       740       750       760       770       780

              790       800       810       820       830       840
pF1KA0 SRTKLHNESKKTAPRQEAIPDLEDSPPVSDSEEQQESARAVPEKSTAPLLDVFSSMLKDT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_149 SRTKLHNESKKTAPRQEAIPDLEDSPPVSDSEEQQESARAVPEKSTAPLLDVFSSMLKDT
              790       800       810       820       830       840

              850       860       870       880       890       900
pF1KA0 TSQHRAHLFDLNCKICTGQVPSAEDEPAPKKQKLSASVKKEDLKSKHDSSAPDPAPDSAD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_149 TSQHRAHLFDLNCKICTGQVPSAEDEPAPKKQKLSASVKKEDLKSKHDSSAPDPAPDSAD
              850       860       870       880       890       900

              910       920       930       940       950       960
pF1KA0 EVMPEAVPEVASEPGLESASHPNVDRTYFPGPPGDGHPEPSPLEDLSPCPASCGSGVVTT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_149 EVMPEAVPEVASEPGLESASHPNVDRTYFPGPPGDGHPEPSPLEDLSPCPASCGSGVVTT
              910       920       930       940       950       960

              970       980       990      1000      1010      1020
pF1KA0 VTVSGRDPRTAPSSSCTAVASAASRPDSTHMVEARQDVPKPVLTSVMVPKSILAKPSSSP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_149 VTVSGRDPRTAPSSSCTAVASAASRPDSTHMVEARQDVPKPVLTSVMVPKSILAKPSSSP
              970       980       990      1000      1010      1020

             1030      1040      1050      1060      1070      1080
pF1KA0 DPRYLSVPPSPNISTSESRSPPEGDTTLFLSRLSTIWKGFINMQSVAKFVTKAYPVSGCF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_149 DPRYLSVPPSPNISTSESRSPPEGDTTLFLSRLSTIWKGFINMQSVAKFVTKAYPVSGCF
             1030      1040      1050      1060      1070      1080

             1090      1100      1110      1120      1130      1140
pF1KA0 DYLSEDLPDTIHIGGRIAPKTVWDYVGKLKSSVSKELCLIRFHPATEEEEVAYISLYSYF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_149 DYLSEDLPDTIHIGGRIAPKTVWDYVGKLKSSVSKELCLIRFHPATEEEEVAYISLYSYF
             1090      1100      1110      1120      1130      1140

             1150      1160      1170      1180                    
pF1KA0 SSRGRFGVVANNNRHVKDLYLIPLSAQDPVPSKLLPFEGPGKRRLSGWR           
       :::::::::::::::::::::::::::::::::::::::::                   
NP_149 SSRGRFGVVANNNRHVKDLYLIPLSAQDPVPSKLLPFEGPGLESPRPNIILGLVICQKIK
             1150      1160      1170      1180      1190      1200

NP_149 RPANSGELDKMDEKRTRLQPEEADVPAYPKVATVPQSEKKPSKYPLCSADAAVSTTPPGS
             1210      1220      1230      1240      1250      1260

>>XP_011526810 (OMIM: 604140) PREDICTED: death-inducer o  (2276 aa)
 initn: 7903 init1: 5276 opt: 5276  Z-score: 2913.6  bits: 552.1 E(85289): 1.5e-155
Smith-Waterman score: 7806; 97.0% identity (97.0% similar) in 1213 aa overlap (5-1181:5-1217)

               10        20        30        40        50        60
pF1KA0 MDDKGDPSNEEAPKAIKPTSKEFRKTWGFRRTTIAKREGAGDAEADPLEPPPPQQQLGLS
           ::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MDDKGDPSNEEAPKAIKPTSKEFRKTWGFRRTTIAKREGAGDAEADPLEPPPPQQQLGLS
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KA0 LRRSGRQPKRTERVEQFLTIARRRGRRSMPVSLEDSGEPTSCPATDAETASEGSVESASE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LRRSGRQPKRTERVEQFLTIARRRGRRSMPVSLEDSGEPTSCPATDAETASEGSVESASE
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KA0 TRSGPQSASTAVKERPASSEKVKGGDDHDDTSDSDSDGLTLKELQNRLRRKREQEPTERP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TRSGPQSASTAVKERPASSEKVKGGDDHDDTSDSDSDGLTLKELQNRLRRKREQEPTERP
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KA0 LKGIQSRLRKKRREEGPAETVGSEASDTVEGVLPSKQEPENDQGVVSQAGKDDRESKLEG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LKGIQSRLRKKRREEGPAETVGSEASDTVEGVLPSKQEPENDQGVVSQAGKDDRESKLEG
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KA0 KAAQDIKDEEPGDLGRPKPECEGYDPNALYCICRQPHNNRFMICCDRCEEWFHGDCVGIS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KAAQDIKDEEPGDLGRPKPECEGYDPNALYCICRQPHNNRFMICCDRCEEWFHGDCVGIS
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KA0 EARGRLLERNGEDYICPNCTILQVQDETHSETADQQEAKWRPGDADGTDCTSIGTIEQKS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EARGRLLERNGEDYICPNCTILQVQDETHSETADQQEAKWRPGDADGTDCTSIGTIEQKS
              310       320       330       340       350       360

              370       380                                        
pF1KA0 SEDQGIKGRIEKAANPSGKKKLKIFQP---------------------------------
       :::::::::::::::::::::::::::                                 
XP_011 SEDQGIKGRIEKAANPSGKKKLKIFQPGPGPVPTQLPVLWQVLEIAVSRSISAFTLLHCI
              370       380       390       400       410       420

          390       400       410       420       430       440    
pF1KA0 ---VIEAPGASKCIGPGCCHVAQPDSVYCSNDCILKHAAATMKFLSSGKEQKPKPKEKMK
          :::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SCKVIEAPGASKCIGPGCCHVAQPDSVYCSNDCILKHAAATMKFLSSGKEQKPKPKEKMK
              430       440       450       460       470       480

          450       460       470       480       490       500    
pF1KA0 MKPEKPSLPKCGAQAGIKISSVHKRPAPEKKETTVKKAVVVPARSEALGKEAACESSTPS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MKPEKPSLPKCGAQAGIKISSVHKRPAPEKKETTVKKAVVVPARSEALGKEAACESSTPS
              490       500       510       520       530       540

          510       520       530       540       550       560    
pF1KA0 WASDHNYNAVKPEKTAAPSPSLLYKSTKEDRRSEEKAAAMAASKKTAPPGSAVGKQPAPR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 WASDHNYNAVKPEKTAAPSPSLLYKSTKEDRRSEEKAAAMAASKKTAPPGSAVGKQPAPR
              550       560       570       580       590       600

          570       580       590       600       610       620    
pF1KA0 NLVPKKSSFANVAAATPAIKKPPSGFKGTIPKRPWLSATPSSGASAARQAGPAPAAATAA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NLVPKKSSFANVAAATPAIKKPPSGFKGTIPKRPWLSATPSSGASAARQAGPAPAAATAA
              610       620       630       640       650       660

          630       640       650       660       670       680    
pF1KA0 SKKFPGSAALVGAVRKPVVPSVPMASPAPGRLGAMSAAPSQPNSQIRQNIRRSLKEILWK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SKKFPGSAALVGAVRKPVVPSVPMASPAPGRLGAMSAAPSQPNSQIRQNIRRSLKEILWK
              670       680       690       700       710       720

          690       700       710       720       730       740    
pF1KA0 RVNDSDDLIMTENEVGKIALHIEKEMFNLFQVTDNRYKSKYRSIMFNLKDPKNQGLFHRV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RVNDSDDLIMTENEVGKIALHIEKEMFNLFQVTDNRYKSKYRSIMFNLKDPKNQGLFHRV
              730       740       750       760       770       780

          750       760       770       780       790       800    
pF1KA0 LREEISLAKLVRLKPEELVSKELSTWKERPARSVMESRTKLHNESKKTAPRQEAIPDLED
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LREEISLAKLVRLKPEELVSKELSTWKERPARSVMESRTKLHNESKKTAPRQEAIPDLED
              790       800       810       820       830       840

          810       820       830       840       850       860    
pF1KA0 SPPVSDSEEQQESARAVPEKSTAPLLDVFSSMLKDTTSQHRAHLFDLNCKICTGQVPSAE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SPPVSDSEEQQESARAVPEKSTAPLLDVFSSMLKDTTSQHRAHLFDLNCKICTGQVPSAE
              850       860       870       880       890       900

          870       880       890       900       910       920    
pF1KA0 DEPAPKKQKLSASVKKEDLKSKHDSSAPDPAPDSADEVMPEAVPEVASEPGLESASHPNV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DEPAPKKQKLSASVKKEDLKSKHDSSAPDPAPDSADEVMPEAVPEVASEPGLESASHPNV
              910       920       930       940       950       960

          930       940       950       960       970       980    
pF1KA0 DRTYFPGPPGDGHPEPSPLEDLSPCPASCGSGVVTTVTVSGRDPRTAPSSSCTAVASAAS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DRTYFPGPPGDGHPEPSPLEDLSPCPASCGSGVVTTVTVSGRDPRTAPSSSCTAVASAAS
              970       980       990      1000      1010      1020

          990      1000      1010      1020      1030      1040    
pF1KA0 RPDSTHMVEARQDVPKPVLTSVMVPKSILAKPSSSPDPRYLSVPPSPNISTSESRSPPEG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RPDSTHMVEARQDVPKPVLTSVMVPKSILAKPSSSPDPRYLSVPPSPNISTSESRSPPEG
             1030      1040      1050      1060      1070      1080

         1050      1060      1070      1080      1090      1100    
pF1KA0 DTTLFLSRLSTIWKGFINMQSVAKFVTKAYPVSGCFDYLSEDLPDTIHIGGRIAPKTVWD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DTTLFLSRLSTIWKGFINMQSVAKFVTKAYPVSGCFDYLSEDLPDTIHIGGRIAPKTVWD
             1090      1100      1110      1120      1130      1140

         1110      1120      1130      1140      1150      1160    
pF1KA0 YVGKLKSSVSKELCLIRFHPATEEEEVAYISLYSYFSSRGRFGVVANNNRHVKDLYLIPL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YVGKLKSSVSKELCLIRFHPATEEEEVAYISLYSYFSSRGRFGVVANNNRHVKDLYLIPL
             1150      1160      1170      1180      1190      1200

         1170      1180                                            
pF1KA0 SAQDPVPSKLLPFEGPGKRRLSGWR                                   
       :::::::::::::::::                                           
XP_011 SAQDPVPSKLLPFEGPGLESPRPNIILGLVICQKIKRPANSGELDKMDEKRTRLQPEEAD
             1210      1220      1230      1240      1250      1260

>>XP_011526807 (OMIM: 604140) PREDICTED: death-inducer o  (2276 aa)
 initn: 7903 init1: 5276 opt: 5276  Z-score: 2913.6  bits: 552.1 E(85289): 1.5e-155
Smith-Waterman score: 7806; 97.0% identity (97.0% similar) in 1213 aa overlap (5-1181:5-1217)

               10        20        30        40        50        60
pF1KA0 MDDKGDPSNEEAPKAIKPTSKEFRKTWGFRRTTIAKREGAGDAEADPLEPPPPQQQLGLS
           ::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MDDKGDPSNEEAPKAIKPTSKEFRKTWGFRRTTIAKREGAGDAEADPLEPPPPQQQLGLS
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KA0 LRRSGRQPKRTERVEQFLTIARRRGRRSMPVSLEDSGEPTSCPATDAETASEGSVESASE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LRRSGRQPKRTERVEQFLTIARRRGRRSMPVSLEDSGEPTSCPATDAETASEGSVESASE
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KA0 TRSGPQSASTAVKERPASSEKVKGGDDHDDTSDSDSDGLTLKELQNRLRRKREQEPTERP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TRSGPQSASTAVKERPASSEKVKGGDDHDDTSDSDSDGLTLKELQNRLRRKREQEPTERP
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KA0 LKGIQSRLRKKRREEGPAETVGSEASDTVEGVLPSKQEPENDQGVVSQAGKDDRESKLEG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LKGIQSRLRKKRREEGPAETVGSEASDTVEGVLPSKQEPENDQGVVSQAGKDDRESKLEG
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KA0 KAAQDIKDEEPGDLGRPKPECEGYDPNALYCICRQPHNNRFMICCDRCEEWFHGDCVGIS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KAAQDIKDEEPGDLGRPKPECEGYDPNALYCICRQPHNNRFMICCDRCEEWFHGDCVGIS
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KA0 EARGRLLERNGEDYICPNCTILQVQDETHSETADQQEAKWRPGDADGTDCTSIGTIEQKS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EARGRLLERNGEDYICPNCTILQVQDETHSETADQQEAKWRPGDADGTDCTSIGTIEQKS
              310       320       330       340       350       360

              370       380                                        
pF1KA0 SEDQGIKGRIEKAANPSGKKKLKIFQP---------------------------------
       :::::::::::::::::::::::::::                                 
XP_011 SEDQGIKGRIEKAANPSGKKKLKIFQPGPGPVPTQLPVLWQVLEIAVSRSISAFTLLHCI
              370       380       390       400       410       420

          390       400       410       420       430       440    
pF1KA0 ---VIEAPGASKCIGPGCCHVAQPDSVYCSNDCILKHAAATMKFLSSGKEQKPKPKEKMK
          :::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SCKVIEAPGASKCIGPGCCHVAQPDSVYCSNDCILKHAAATMKFLSSGKEQKPKPKEKMK
              430       440       450       460       470       480

          450       460       470       480       490       500    
pF1KA0 MKPEKPSLPKCGAQAGIKISSVHKRPAPEKKETTVKKAVVVPARSEALGKEAACESSTPS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MKPEKPSLPKCGAQAGIKISSVHKRPAPEKKETTVKKAVVVPARSEALGKEAACESSTPS
              490       500       510       520       530       540

          510       520       530       540       550       560    
pF1KA0 WASDHNYNAVKPEKTAAPSPSLLYKSTKEDRRSEEKAAAMAASKKTAPPGSAVGKQPAPR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 WASDHNYNAVKPEKTAAPSPSLLYKSTKEDRRSEEKAAAMAASKKTAPPGSAVGKQPAPR
              550       560       570       580       590       600

          570       580       590       600       610       620    
pF1KA0 NLVPKKSSFANVAAATPAIKKPPSGFKGTIPKRPWLSATPSSGASAARQAGPAPAAATAA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NLVPKKSSFANVAAATPAIKKPPSGFKGTIPKRPWLSATPSSGASAARQAGPAPAAATAA
              610       620       630       640       650       660

          630       640       650       660       670       680    
pF1KA0 SKKFPGSAALVGAVRKPVVPSVPMASPAPGRLGAMSAAPSQPNSQIRQNIRRSLKEILWK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SKKFPGSAALVGAVRKPVVPSVPMASPAPGRLGAMSAAPSQPNSQIRQNIRRSLKEILWK
              670       680       690       700       710       720

          690       700       710       720       730       740    
pF1KA0 RVNDSDDLIMTENEVGKIALHIEKEMFNLFQVTDNRYKSKYRSIMFNLKDPKNQGLFHRV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RVNDSDDLIMTENEVGKIALHIEKEMFNLFQVTDNRYKSKYRSIMFNLKDPKNQGLFHRV
              730       740       750       760       770       780

          750       760       770       780       790       800    
pF1KA0 LREEISLAKLVRLKPEELVSKELSTWKERPARSVMESRTKLHNESKKTAPRQEAIPDLED
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LREEISLAKLVRLKPEELVSKELSTWKERPARSVMESRTKLHNESKKTAPRQEAIPDLED
              790       800       810       820       830       840

          810       820       830       840       850       860    
pF1KA0 SPPVSDSEEQQESARAVPEKSTAPLLDVFSSMLKDTTSQHRAHLFDLNCKICTGQVPSAE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SPPVSDSEEQQESARAVPEKSTAPLLDVFSSMLKDTTSQHRAHLFDLNCKICTGQVPSAE
              850       860       870       880       890       900

          870       880       890       900       910       920    
pF1KA0 DEPAPKKQKLSASVKKEDLKSKHDSSAPDPAPDSADEVMPEAVPEVASEPGLESASHPNV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DEPAPKKQKLSASVKKEDLKSKHDSSAPDPAPDSADEVMPEAVPEVASEPGLESASHPNV
              910       920       930       940       950       960

          930       940       950       960       970       980    
pF1KA0 DRTYFPGPPGDGHPEPSPLEDLSPCPASCGSGVVTTVTVSGRDPRTAPSSSCTAVASAAS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DRTYFPGPPGDGHPEPSPLEDLSPCPASCGSGVVTTVTVSGRDPRTAPSSSCTAVASAAS
              970       980       990      1000      1010      1020

          990      1000      1010      1020      1030      1040    
pF1KA0 RPDSTHMVEARQDVPKPVLTSVMVPKSILAKPSSSPDPRYLSVPPSPNISTSESRSPPEG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RPDSTHMVEARQDVPKPVLTSVMVPKSILAKPSSSPDPRYLSVPPSPNISTSESRSPPEG
             1030      1040      1050      1060      1070      1080

         1050      1060      1070      1080      1090      1100    
pF1KA0 DTTLFLSRLSTIWKGFINMQSVAKFVTKAYPVSGCFDYLSEDLPDTIHIGGRIAPKTVWD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DTTLFLSRLSTIWKGFINMQSVAKFVTKAYPVSGCFDYLSEDLPDTIHIGGRIAPKTVWD
             1090      1100      1110      1120      1130      1140

         1110      1120      1130      1140      1150      1160    
pF1KA0 YVGKLKSSVSKELCLIRFHPATEEEEVAYISLYSYFSSRGRFGVVANNNRHVKDLYLIPL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YVGKLKSSVSKELCLIRFHPATEEEEVAYISLYSYFSSRGRFGVVANNNRHVKDLYLIPL
             1150      1160      1170      1180      1190      1200

         1170      1180                                            
pF1KA0 SAQDPVPSKLLPFEGPGKRRLSGWR                                   
       :::::::::::::::::                                           
XP_011 SAQDPVPSKLLPFEGPGLESPRPNIILGLVICQKIKRPANSGELDKMDEKRTRLQPEEAD
             1210      1220      1230      1240      1250      1260

>>XP_011526806 (OMIM: 604140) PREDICTED: death-inducer o  (2276 aa)
 initn: 7903 init1: 5276 opt: 5276  Z-score: 2913.6  bits: 552.1 E(85289): 1.5e-155
Smith-Waterman score: 7806; 97.0% identity (97.0% similar) in 1213 aa overlap (5-1181:5-1217)

               10        20        30        40        50        60
pF1KA0 MDDKGDPSNEEAPKAIKPTSKEFRKTWGFRRTTIAKREGAGDAEADPLEPPPPQQQLGLS
           ::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MDDKGDPSNEEAPKAIKPTSKEFRKTWGFRRTTIAKREGAGDAEADPLEPPPPQQQLGLS
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KA0 LRRSGRQPKRTERVEQFLTIARRRGRRSMPVSLEDSGEPTSCPATDAETASEGSVESASE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LRRSGRQPKRTERVEQFLTIARRRGRRSMPVSLEDSGEPTSCPATDAETASEGSVESASE
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KA0 TRSGPQSASTAVKERPASSEKVKGGDDHDDTSDSDSDGLTLKELQNRLRRKREQEPTERP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TRSGPQSASTAVKERPASSEKVKGGDDHDDTSDSDSDGLTLKELQNRLRRKREQEPTERP
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KA0 LKGIQSRLRKKRREEGPAETVGSEASDTVEGVLPSKQEPENDQGVVSQAGKDDRESKLEG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LKGIQSRLRKKRREEGPAETVGSEASDTVEGVLPSKQEPENDQGVVSQAGKDDRESKLEG
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KA0 KAAQDIKDEEPGDLGRPKPECEGYDPNALYCICRQPHNNRFMICCDRCEEWFHGDCVGIS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KAAQDIKDEEPGDLGRPKPECEGYDPNALYCICRQPHNNRFMICCDRCEEWFHGDCVGIS
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KA0 EARGRLLERNGEDYICPNCTILQVQDETHSETADQQEAKWRPGDADGTDCTSIGTIEQKS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EARGRLLERNGEDYICPNCTILQVQDETHSETADQQEAKWRPGDADGTDCTSIGTIEQKS
              310       320       330       340       350       360

              370       380                                        
pF1KA0 SEDQGIKGRIEKAANPSGKKKLKIFQP---------------------------------
       :::::::::::::::::::::::::::                                 
XP_011 SEDQGIKGRIEKAANPSGKKKLKIFQPGPGPVPTQLPVLWQVLEIAVSRSISAFTLLHCI
              370       380       390       400       410       420

          390       400       410       420       430       440    
pF1KA0 ---VIEAPGASKCIGPGCCHVAQPDSVYCSNDCILKHAAATMKFLSSGKEQKPKPKEKMK
          :::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SCKVIEAPGASKCIGPGCCHVAQPDSVYCSNDCILKHAAATMKFLSSGKEQKPKPKEKMK
              430       440       450       460       470       480

          450       460       470       480       490       500    
pF1KA0 MKPEKPSLPKCGAQAGIKISSVHKRPAPEKKETTVKKAVVVPARSEALGKEAACESSTPS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MKPEKPSLPKCGAQAGIKISSVHKRPAPEKKETTVKKAVVVPARSEALGKEAACESSTPS
              490       500       510       520       530       540

          510       520       530       540       550       560    
pF1KA0 WASDHNYNAVKPEKTAAPSPSLLYKSTKEDRRSEEKAAAMAASKKTAPPGSAVGKQPAPR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 WASDHNYNAVKPEKTAAPSPSLLYKSTKEDRRSEEKAAAMAASKKTAPPGSAVGKQPAPR
              550       560       570       580       590       600

          570       580       590       600       610       620    
pF1KA0 NLVPKKSSFANVAAATPAIKKPPSGFKGTIPKRPWLSATPSSGASAARQAGPAPAAATAA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NLVPKKSSFANVAAATPAIKKPPSGFKGTIPKRPWLSATPSSGASAARQAGPAPAAATAA
              610       620       630       640       650       660

          630       640       650       660       670       680    
pF1KA0 SKKFPGSAALVGAVRKPVVPSVPMASPAPGRLGAMSAAPSQPNSQIRQNIRRSLKEILWK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SKKFPGSAALVGAVRKPVVPSVPMASPAPGRLGAMSAAPSQPNSQIRQNIRRSLKEILWK
              670       680       690       700       710       720

          690       700       710       720       730       740    
pF1KA0 RVNDSDDLIMTENEVGKIALHIEKEMFNLFQVTDNRYKSKYRSIMFNLKDPKNQGLFHRV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RVNDSDDLIMTENEVGKIALHIEKEMFNLFQVTDNRYKSKYRSIMFNLKDPKNQGLFHRV
              730       740       750       760       770       780

          750       760       770       780       790       800    
pF1KA0 LREEISLAKLVRLKPEELVSKELSTWKERPARSVMESRTKLHNESKKTAPRQEAIPDLED
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LREEISLAKLVRLKPEELVSKELSTWKERPARSVMESRTKLHNESKKTAPRQEAIPDLED
              790       800       810       820       830       840

          810       820       830       840       850       860    
pF1KA0 SPPVSDSEEQQESARAVPEKSTAPLLDVFSSMLKDTTSQHRAHLFDLNCKICTGQVPSAE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SPPVSDSEEQQESARAVPEKSTAPLLDVFSSMLKDTTSQHRAHLFDLNCKICTGQVPSAE
              850       860       870       880       890       900

          870       880       890       900       910       920    
pF1KA0 DEPAPKKQKLSASVKKEDLKSKHDSSAPDPAPDSADEVMPEAVPEVASEPGLESASHPNV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DEPAPKKQKLSASVKKEDLKSKHDSSAPDPAPDSADEVMPEAVPEVASEPGLESASHPNV
              910       920       930       940       950       960

          930       940       950       960       970       980    
pF1KA0 DRTYFPGPPGDGHPEPSPLEDLSPCPASCGSGVVTTVTVSGRDPRTAPSSSCTAVASAAS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DRTYFPGPPGDGHPEPSPLEDLSPCPASCGSGVVTTVTVSGRDPRTAPSSSCTAVASAAS
              970       980       990      1000      1010      1020

          990      1000      1010      1020      1030      1040    
pF1KA0 RPDSTHMVEARQDVPKPVLTSVMVPKSILAKPSSSPDPRYLSVPPSPNISTSESRSPPEG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RPDSTHMVEARQDVPKPVLTSVMVPKSILAKPSSSPDPRYLSVPPSPNISTSESRSPPEG
             1030      1040      1050      1060      1070      1080

         1050      1060      1070      1080      1090      1100    
pF1KA0 DTTLFLSRLSTIWKGFINMQSVAKFVTKAYPVSGCFDYLSEDLPDTIHIGGRIAPKTVWD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DTTLFLSRLSTIWKGFINMQSVAKFVTKAYPVSGCFDYLSEDLPDTIHIGGRIAPKTVWD
             1090      1100      1110      1120      1130      1140

         1110      1120      1130      1140      1150      1160    
pF1KA0 YVGKLKSSVSKELCLIRFHPATEEEEVAYISLYSYFSSRGRFGVVANNNRHVKDLYLIPL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YVGKLKSSVSKELCLIRFHPATEEEEVAYISLYSYFSSRGRFGVVANNNRHVKDLYLIPL
             1150      1160      1170      1180      1190      1200

         1170      1180                                            
pF1KA0 SAQDPVPSKLLPFEGPGKRRLSGWR                                   
       :::::::::::::::::                                           
XP_011 SAQDPVPSKLLPFEGPGLESPRPNIILGLVICQKIKRPANSGELDKMDEKRTRLQPEEAD
             1210      1220      1230      1240      1250      1260

>>XP_011526809 (OMIM: 604140) PREDICTED: death-inducer o  (2276 aa)
 initn: 7903 init1: 5276 opt: 5276  Z-score: 2913.6  bits: 552.1 E(85289): 1.5e-155
Smith-Waterman score: 7806; 97.0% identity (97.0% similar) in 1213 aa overlap (5-1181:5-1217)

               10        20        30        40        50        60
pF1KA0 MDDKGDPSNEEAPKAIKPTSKEFRKTWGFRRTTIAKREGAGDAEADPLEPPPPQQQLGLS
           ::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MDDKGDPSNEEAPKAIKPTSKEFRKTWGFRRTTIAKREGAGDAEADPLEPPPPQQQLGLS
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KA0 LRRSGRQPKRTERVEQFLTIARRRGRRSMPVSLEDSGEPTSCPATDAETASEGSVESASE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LRRSGRQPKRTERVEQFLTIARRRGRRSMPVSLEDSGEPTSCPATDAETASEGSVESASE
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KA0 TRSGPQSASTAVKERPASSEKVKGGDDHDDTSDSDSDGLTLKELQNRLRRKREQEPTERP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TRSGPQSASTAVKERPASSEKVKGGDDHDDTSDSDSDGLTLKELQNRLRRKREQEPTERP
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KA0 LKGIQSRLRKKRREEGPAETVGSEASDTVEGVLPSKQEPENDQGVVSQAGKDDRESKLEG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LKGIQSRLRKKRREEGPAETVGSEASDTVEGVLPSKQEPENDQGVVSQAGKDDRESKLEG
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KA0 KAAQDIKDEEPGDLGRPKPECEGYDPNALYCICRQPHNNRFMICCDRCEEWFHGDCVGIS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KAAQDIKDEEPGDLGRPKPECEGYDPNALYCICRQPHNNRFMICCDRCEEWFHGDCVGIS
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KA0 EARGRLLERNGEDYICPNCTILQVQDETHSETADQQEAKWRPGDADGTDCTSIGTIEQKS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EARGRLLERNGEDYICPNCTILQVQDETHSETADQQEAKWRPGDADGTDCTSIGTIEQKS
              310       320       330       340       350       360

              370       380                                        
pF1KA0 SEDQGIKGRIEKAANPSGKKKLKIFQP---------------------------------
       :::::::::::::::::::::::::::                                 
XP_011 SEDQGIKGRIEKAANPSGKKKLKIFQPGPGPVPTQLPVLWQVLEIAVSRSISAFTLLHCI
              370       380       390       400       410       420

          390       400       410       420       430       440    
pF1KA0 ---VIEAPGASKCIGPGCCHVAQPDSVYCSNDCILKHAAATMKFLSSGKEQKPKPKEKMK
          :::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SCKVIEAPGASKCIGPGCCHVAQPDSVYCSNDCILKHAAATMKFLSSGKEQKPKPKEKMK
              430       440       450       460       470       480

          450       460       470       480       490       500    
pF1KA0 MKPEKPSLPKCGAQAGIKISSVHKRPAPEKKETTVKKAVVVPARSEALGKEAACESSTPS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MKPEKPSLPKCGAQAGIKISSVHKRPAPEKKETTVKKAVVVPARSEALGKEAACESSTPS
              490       500       510       520       530       540

          510       520       530       540       550       560    
pF1KA0 WASDHNYNAVKPEKTAAPSPSLLYKSTKEDRRSEEKAAAMAASKKTAPPGSAVGKQPAPR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 WASDHNYNAVKPEKTAAPSPSLLYKSTKEDRRSEEKAAAMAASKKTAPPGSAVGKQPAPR
              550       560       570       580       590       600

          570       580       590       600       610       620    
pF1KA0 NLVPKKSSFANVAAATPAIKKPPSGFKGTIPKRPWLSATPSSGASAARQAGPAPAAATAA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NLVPKKSSFANVAAATPAIKKPPSGFKGTIPKRPWLSATPSSGASAARQAGPAPAAATAA
              610       620       630       640       650       660

          630       640       650       660       670       680    
pF1KA0 SKKFPGSAALVGAVRKPVVPSVPMASPAPGRLGAMSAAPSQPNSQIRQNIRRSLKEILWK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SKKFPGSAALVGAVRKPVVPSVPMASPAPGRLGAMSAAPSQPNSQIRQNIRRSLKEILWK
              670       680       690       700       710       720

          690       700       710       720       730       740    
pF1KA0 RVNDSDDLIMTENEVGKIALHIEKEMFNLFQVTDNRYKSKYRSIMFNLKDPKNQGLFHRV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RVNDSDDLIMTENEVGKIALHIEKEMFNLFQVTDNRYKSKYRSIMFNLKDPKNQGLFHRV
              730       740       750       760       770       780

          750       760       770       780       790       800    
pF1KA0 LREEISLAKLVRLKPEELVSKELSTWKERPARSVMESRTKLHNESKKTAPRQEAIPDLED
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LREEISLAKLVRLKPEELVSKELSTWKERPARSVMESRTKLHNESKKTAPRQEAIPDLED
              790       800       810       820       830       840

          810       820       830       840       850       860    
pF1KA0 SPPVSDSEEQQESARAVPEKSTAPLLDVFSSMLKDTTSQHRAHLFDLNCKICTGQVPSAE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SPPVSDSEEQQESARAVPEKSTAPLLDVFSSMLKDTTSQHRAHLFDLNCKICTGQVPSAE
              850       860       870       880       890       900

          870       880       890       900       910       920    
pF1KA0 DEPAPKKQKLSASVKKEDLKSKHDSSAPDPAPDSADEVMPEAVPEVASEPGLESASHPNV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DEPAPKKQKLSASVKKEDLKSKHDSSAPDPAPDSADEVMPEAVPEVASEPGLESASHPNV
              910       920       930       940       950       960

          930       940       950       960       970       980    
pF1KA0 DRTYFPGPPGDGHPEPSPLEDLSPCPASCGSGVVTTVTVSGRDPRTAPSSSCTAVASAAS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DRTYFPGPPGDGHPEPSPLEDLSPCPASCGSGVVTTVTVSGRDPRTAPSSSCTAVASAAS
              970       980       990      1000      1010      1020

          990      1000      1010      1020      1030      1040    
pF1KA0 RPDSTHMVEARQDVPKPVLTSVMVPKSILAKPSSSPDPRYLSVPPSPNISTSESRSPPEG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RPDSTHMVEARQDVPKPVLTSVMVPKSILAKPSSSPDPRYLSVPPSPNISTSESRSPPEG
             1030      1040      1050      1060      1070      1080

         1050      1060      1070      1080      1090      1100    
pF1KA0 DTTLFLSRLSTIWKGFINMQSVAKFVTKAYPVSGCFDYLSEDLPDTIHIGGRIAPKTVWD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DTTLFLSRLSTIWKGFINMQSVAKFVTKAYPVSGCFDYLSEDLPDTIHIGGRIAPKTVWD
             1090      1100      1110      1120      1130      1140

         1110      1120      1130      1140      1150      1160    
pF1KA0 YVGKLKSSVSKELCLIRFHPATEEEEVAYISLYSYFSSRGRFGVVANNNRHVKDLYLIPL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YVGKLKSSVSKELCLIRFHPATEEEEVAYISLYSYFSSRGRFGVVANNNRHVKDLYLIPL
             1150      1160      1170      1180      1190      1200

         1170      1180                                            
pF1KA0 SAQDPVPSKLLPFEGPGKRRLSGWR                                   
       :::::::::::::::::                                           
XP_011 SAQDPVPSKLLPFEGPGLESPRPNIILGLVICQKIKRPANSGELDKMDEKRTRLQPEEAD
             1210      1220      1230      1240      1250      1260

>>XP_011526808 (OMIM: 604140) PREDICTED: death-inducer o  (2276 aa)
 initn: 7903 init1: 5276 opt: 5276  Z-score: 2913.6  bits: 552.1 E(85289): 1.5e-155
Smith-Waterman score: 7806; 97.0% identity (97.0% similar) in 1213 aa overlap (5-1181:5-1217)

               10        20        30        40        50        60
pF1KA0 MDDKGDPSNEEAPKAIKPTSKEFRKTWGFRRTTIAKREGAGDAEADPLEPPPPQQQLGLS
           ::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MDDKGDPSNEEAPKAIKPTSKEFRKTWGFRRTTIAKREGAGDAEADPLEPPPPQQQLGLS
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KA0 LRRSGRQPKRTERVEQFLTIARRRGRRSMPVSLEDSGEPTSCPATDAETASEGSVESASE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LRRSGRQPKRTERVEQFLTIARRRGRRSMPVSLEDSGEPTSCPATDAETASEGSVESASE
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KA0 TRSGPQSASTAVKERPASSEKVKGGDDHDDTSDSDSDGLTLKELQNRLRRKREQEPTERP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TRSGPQSASTAVKERPASSEKVKGGDDHDDTSDSDSDGLTLKELQNRLRRKREQEPTERP
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KA0 LKGIQSRLRKKRREEGPAETVGSEASDTVEGVLPSKQEPENDQGVVSQAGKDDRESKLEG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LKGIQSRLRKKRREEGPAETVGSEASDTVEGVLPSKQEPENDQGVVSQAGKDDRESKLEG
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KA0 KAAQDIKDEEPGDLGRPKPECEGYDPNALYCICRQPHNNRFMICCDRCEEWFHGDCVGIS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KAAQDIKDEEPGDLGRPKPECEGYDPNALYCICRQPHNNRFMICCDRCEEWFHGDCVGIS
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KA0 EARGRLLERNGEDYICPNCTILQVQDETHSETADQQEAKWRPGDADGTDCTSIGTIEQKS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EARGRLLERNGEDYICPNCTILQVQDETHSETADQQEAKWRPGDADGTDCTSIGTIEQKS
              310       320       330       340       350       360

              370       380                                        
pF1KA0 SEDQGIKGRIEKAANPSGKKKLKIFQP---------------------------------
       :::::::::::::::::::::::::::                                 
XP_011 SEDQGIKGRIEKAANPSGKKKLKIFQPGPGPVPTQLPVLWQVLEIAVSRSISAFTLLHCI
              370       380       390       400       410       420

          390       400       410       420       430       440    
pF1KA0 ---VIEAPGASKCIGPGCCHVAQPDSVYCSNDCILKHAAATMKFLSSGKEQKPKPKEKMK
          :::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SCKVIEAPGASKCIGPGCCHVAQPDSVYCSNDCILKHAAATMKFLSSGKEQKPKPKEKMK
              430       440       450       460       470       480

          450       460       470       480       490       500    
pF1KA0 MKPEKPSLPKCGAQAGIKISSVHKRPAPEKKETTVKKAVVVPARSEALGKEAACESSTPS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MKPEKPSLPKCGAQAGIKISSVHKRPAPEKKETTVKKAVVVPARSEALGKEAACESSTPS
              490       500       510       520       530       540

          510       520       530       540       550       560    
pF1KA0 WASDHNYNAVKPEKTAAPSPSLLYKSTKEDRRSEEKAAAMAASKKTAPPGSAVGKQPAPR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 WASDHNYNAVKPEKTAAPSPSLLYKSTKEDRRSEEKAAAMAASKKTAPPGSAVGKQPAPR
              550       560       570       580       590       600

          570       580       590       600       610       620    
pF1KA0 NLVPKKSSFANVAAATPAIKKPPSGFKGTIPKRPWLSATPSSGASAARQAGPAPAAATAA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NLVPKKSSFANVAAATPAIKKPPSGFKGTIPKRPWLSATPSSGASAARQAGPAPAAATAA
              610       620       630       640       650       660

          630       640       650       660       670       680    
pF1KA0 SKKFPGSAALVGAVRKPVVPSVPMASPAPGRLGAMSAAPSQPNSQIRQNIRRSLKEILWK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SKKFPGSAALVGAVRKPVVPSVPMASPAPGRLGAMSAAPSQPNSQIRQNIRRSLKEILWK
              670       680       690       700       710       720

          690       700       710       720       730       740    
pF1KA0 RVNDSDDLIMTENEVGKIALHIEKEMFNLFQVTDNRYKSKYRSIMFNLKDPKNQGLFHRV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RVNDSDDLIMTENEVGKIALHIEKEMFNLFQVTDNRYKSKYRSIMFNLKDPKNQGLFHRV
              730       740       750       760       770       780

          750       760       770       780       790       800    
pF1KA0 LREEISLAKLVRLKPEELVSKELSTWKERPARSVMESRTKLHNESKKTAPRQEAIPDLED
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LREEISLAKLVRLKPEELVSKELSTWKERPARSVMESRTKLHNESKKTAPRQEAIPDLED
              790       800       810       820       830       840

          810       820       830       840       850       860    
pF1KA0 SPPVSDSEEQQESARAVPEKSTAPLLDVFSSMLKDTTSQHRAHLFDLNCKICTGQVPSAE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SPPVSDSEEQQESARAVPEKSTAPLLDVFSSMLKDTTSQHRAHLFDLNCKICTGQVPSAE
              850       860       870       880       890       900

          870       880       890       900       910       920    
pF1KA0 DEPAPKKQKLSASVKKEDLKSKHDSSAPDPAPDSADEVMPEAVPEVASEPGLESASHPNV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DEPAPKKQKLSASVKKEDLKSKHDSSAPDPAPDSADEVMPEAVPEVASEPGLESASHPNV
              910       920       930       940       950       960

          930       940       950       960       970       980    
pF1KA0 DRTYFPGPPGDGHPEPSPLEDLSPCPASCGSGVVTTVTVSGRDPRTAPSSSCTAVASAAS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DRTYFPGPPGDGHPEPSPLEDLSPCPASCGSGVVTTVTVSGRDPRTAPSSSCTAVASAAS
              970       980       990      1000      1010      1020

          990      1000      1010      1020      1030      1040    
pF1KA0 RPDSTHMVEARQDVPKPVLTSVMVPKSILAKPSSSPDPRYLSVPPSPNISTSESRSPPEG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RPDSTHMVEARQDVPKPVLTSVMVPKSILAKPSSSPDPRYLSVPPSPNISTSESRSPPEG
             1030      1040      1050      1060      1070      1080

         1050      1060      1070      1080      1090      1100    
pF1KA0 DTTLFLSRLSTIWKGFINMQSVAKFVTKAYPVSGCFDYLSEDLPDTIHIGGRIAPKTVWD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DTTLFLSRLSTIWKGFINMQSVAKFVTKAYPVSGCFDYLSEDLPDTIHIGGRIAPKTVWD
             1090      1100      1110      1120      1130      1140

         1110      1120      1130      1140      1150      1160    
pF1KA0 YVGKLKSSVSKELCLIRFHPATEEEEVAYISLYSYFSSRGRFGVVANNNRHVKDLYLIPL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YVGKLKSSVSKELCLIRFHPATEEEEVAYISLYSYFSSRGRFGVVANNNRHVKDLYLIPL
             1150      1160      1170      1180      1190      1200

         1170      1180                                            
pF1KA0 SAQDPVPSKLLPFEGPGKRRLSGWR                                   
       :::::::::::::::::                                           
XP_011 SAQDPVPSKLLPFEGPGLESPRPNIILGLVICQKIKRPANSGELDKMDEKRTRLQPEEAD
             1210      1220      1230      1240      1250      1260




1189 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Thu Nov  3 09:21:52 2016 done: Thu Nov  3 09:21:54 2016
 Total Scan time: 15.060 Total Display time:  0.550

Function used was FASTA [36.3.4 Apr, 2011]
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