Result of FASTA (omim) for pF1KSDA0846
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KSDA0846, 689 aa
  1>>>pF1KSDA0846 689 - 689 aa - 689 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 6.3167+/-0.000436; mu= 15.7893+/- 0.027
 mean_var=122.6067+/-24.685, 0's: 0 Z-trim(115.5): 363  B-trim: 372 in 2/52
 Lambda= 0.115829
 statistics sampled from 25561 (26017) to 25561 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.656), E-opt: 0.2 (0.305), width:  16
 Scan time: 10.050

The best scores are:                                      opt bits E(85289)
XP_016859252 (OMIM: 609531) PREDICTED: ras guanyl- ( 689) 4677 793.4       0
XP_016859251 (OMIM: 609531) PREDICTED: ras guanyl- ( 689) 4677 793.4       0
XP_005264303 (OMIM: 609531) PREDICTED: ras guanyl- ( 689) 4677 793.4       0
NP_056191 (OMIM: 609531) ras guanyl-releasing prot ( 689) 4677 793.4       0
XP_011531048 (OMIM: 609531) PREDICTED: ras guanyl- ( 690) 4665 791.4       0
XP_016859248 (OMIM: 609531) PREDICTED: ras guanyl- ( 690) 4665 791.4       0
XP_011531049 (OMIM: 609531) PREDICTED: ras guanyl- ( 690) 4665 791.4       0
XP_011531050 (OMIM: 609531) PREDICTED: ras guanyl- ( 690) 4665 791.4       0
XP_016859250 (OMIM: 609531) PREDICTED: ras guanyl- ( 690) 4665 791.4       0
NP_001132960 (OMIM: 609531) ras guanyl-releasing p ( 690) 4665 791.4       0
XP_016859249 (OMIM: 609531) PREDICTED: ras guanyl- ( 690) 4665 791.4       0
NP_733772 (OMIM: 609531) ras guanyl-releasing prot ( 690) 4665 791.4       0
XP_016877349 (OMIM: 603962) PREDICTED: RAS guanyl- ( 749) 2315 398.7 4.1e-110
NP_005730 (OMIM: 603962) RAS guanyl-releasing prot ( 797) 2315 398.8 4.2e-110
XP_011519453 (OMIM: 603962) PREDICTED: RAS guanyl- ( 632) 2235 385.3 3.8e-106
XP_005254171 (OMIM: 603962) PREDICTED: RAS guanyl- ( 746) 2093 361.6   6e-99
NP_722541 (OMIM: 605577,615888) RAS guanyl-releasi ( 609) 2056 355.4 3.7e-97
NP_001092140 (OMIM: 605577,615888) RAS guanyl-rele ( 609) 2056 355.4 3.7e-97
NP_001092141 (OMIM: 605577,615888) RAS guanyl-rele ( 609) 2056 355.4 3.7e-97
XP_011543022 (OMIM: 605577,615888) PREDICTED: RAS  ( 610) 2056 355.4 3.7e-97
XP_011543024 (OMIM: 605577,615888) PREDICTED: RAS  ( 610) 2056 355.4 3.7e-97
XP_016872573 (OMIM: 605577,615888) PREDICTED: RAS  ( 610) 2056 355.4 3.7e-97
XP_011543023 (OMIM: 605577,615888) PREDICTED: RAS  ( 610) 2056 355.4 3.7e-97
XP_011543025 (OMIM: 605577,615888) PREDICTED: RAS  ( 610) 2056 355.4 3.7e-97
XP_005273764 (OMIM: 605577,615888) PREDICTED: RAS  ( 714) 1905 330.2 1.7e-89
XP_011543020 (OMIM: 605577,615888) PREDICTED: RAS  ( 715) 1905 330.2 1.7e-89
XP_016872572 (OMIM: 605577,615888) PREDICTED: RAS  ( 897) 1905 330.3   2e-89
XP_016872571 (OMIM: 605577,615888) PREDICTED: RAS  ( 898) 1905 330.3   2e-89
XP_016872574 (OMIM: 605577,615888) PREDICTED: RAS  ( 551) 1851 321.1 7.1e-87
NP_733749 (OMIM: 607320) RAS guanyl-releasing prot ( 673) 1648 287.2 1.3e-76
NP_001305327 (OMIM: 605577,615888) RAS guanyl-rele ( 464) 1629 283.9 9.2e-76
XP_011543027 (OMIM: 605577,615888) PREDICTED: RAS  ( 465) 1629 283.9 9.2e-76
XP_016872575 (OMIM: 605577,615888) PREDICTED: RAS  ( 465) 1629 283.9 9.2e-76
NP_001139674 (OMIM: 607320) RAS guanyl-releasing p ( 659) 1436 251.8 6.1e-66
NP_001293015 (OMIM: 603962) RAS guanyl-releasing p ( 597) 1421 249.3 3.2e-65
NP_001122074 (OMIM: 603962) RAS guanyl-releasing p ( 762) 1421 249.4 3.9e-65
NP_001139677 (OMIM: 607320) RAS guanyl-releasing p ( 639) 1203 212.9 3.1e-54
NP_001139679 (OMIM: 607320) RAS guanyl-releasing p ( 576)  929 167.0 1.8e-40
NP_001139676 (OMIM: 607320) RAS guanyl-releasing p ( 604)  728 133.5 2.4e-30
NP_001139675 (OMIM: 607320) RAS guanyl-releasing p ( 581)  726 133.1 2.9e-30
NP_001139678 (OMIM: 607320) RAS guanyl-releasing p ( 484)  678 125.0 6.6e-28
XP_016865171 (OMIM: 606614) PREDICTED: ras-specifi (1142)  436 84.9 1.8e-15
NP_008840 (OMIM: 606614) ras-specific guanine nucl (1237)  436 85.0 1.9e-15
NP_722522 (OMIM: 606600) ras-specific guanine nucl ( 489)  397 78.1   9e-14
NP_001139120 (OMIM: 606600) ras-specific guanine n (1257)  397 78.4 1.8e-13
XP_016877945 (OMIM: 606600) PREDICTED: ras-specifi (1260)  397 78.4 1.8e-13
XP_016877944 (OMIM: 606600) PREDICTED: ras-specifi (1270)  397 78.4 1.8e-13
NP_002882 (OMIM: 606600) ras-specific guanine nucl (1273)  397 78.4 1.8e-13
NP_005303 (OMIM: 600303) rap guanine nucleotide ex (1077)  385 76.4 6.5e-13
NP_001291204 (OMIM: 600303) rap guanine nucleotide (1094)  385 76.4 6.5e-13


>>XP_016859252 (OMIM: 609531) PREDICTED: ras guanyl-rele  (689 aa)
 initn: 4677 init1: 4677 opt: 4677  Z-score: 4231.6  bits: 793.4 E(85289):    0
Smith-Waterman score: 4677; 100.0% identity (100.0% similar) in 689 aa overlap (1-689:1-689)

               10        20        30        40        50        60
pF1KSD MGSSGLGKAATLDELLCTCIEMFDDNGELDNSYLPRIVLLMHRWYLSSTELAEKLLCMYR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MGSSGLGKAATLDELLCTCIEMFDDNGELDNSYLPRIVLLMHRWYLSSTELAEKLLCMYR
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KSD NATGESCNEFRLKICYFMRYWILKFPAEFNLDLGLIRMTEEFREVASQLGYEKHVSLIDI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NATGESCNEFRLKICYFMRYWILKFPAEFNLDLGLIRMTEEFREVASQLGYEKHVSLIDI
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KSD SSIPSYDWMRRVTQRKKVSKKGKACLLFDHLEPIELAEHLTFLEHKSFRRISFTDYQSYV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SSIPSYDWMRRVTQRKKVSKKGKACLLFDHLEPIELAEHLTFLEHKSFRRISFTDYQSYV
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KSD IHGCLENNPTLERSIALFNGISKWVQLMVLSKPTPQQRAEVITKFINVAKKLLQLKNFNT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IHGCLENNPTLERSIALFNGISKWVQLMVLSKPTPQQRAEVITKFINVAKKLLQLKNFNT
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KSD LMAVVGGLSHSSISRLKETHSHLSSEVTKNWNEMTELVSSNGNYCNYRKAFADCDGFKIP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LMAVVGGLSHSSISRLKETHSHLSSEVTKNWNEMTELVSSNGNYCNYRKAFADCDGFKIP
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KSD ILGVHLKDLIAVHVIFPDWTEENKVNIVKMHQLSVTLSELVSLQNASHHLEPNMDLINLL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ILGVHLKDLIAVHVIFPDWTEENKVNIVKMHQLSVTLSELVSLQNASHHLEPNMDLINLL
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KSD TLSLDLYHTEDDIYKLSLVLEPRNSKSPTSPTTPNKPVVPLEWALGVMPKPDPTVINKHI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TLSLDLYHTEDDIYKLSLVLEPRNSKSPTSPTTPNKPVVPLEWALGVMPKPDPTVINKHI
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KSD RKLVESVFRNYDHDHDGYISQEDFESIAANFPFLDSFCVLDKDQDGLISKDEMMAYFLRA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RKLVESVFRNYDHDHDGYISQEDFESIAANFPFLDSFCVLDKDQDGLISKDEMMAYFLRA
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KSD KSQLHCKMGPGFIHNFQEMTYLKPTFCEHCAGFLWGIIKQGYKCKDCGANCHKQCKDLLV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KSQLHCKMGPGFIHNFQEMTYLKPTFCEHCAGFLWGIIKQGYKCKDCGANCHKQCKDLLV
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KSD LACRRFARAPSLSSGHGSLPGSPSLPPAQDEVFEFPGVTAGHRDLDSRAITLVTGSSRKI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LACRRFARAPSLSSGHGSLPGSPSLPPAQDEVFEFPGVTAGHRDLDSRAITLVTGSSRKI
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KSD SVRLQRATTSQATQTEPVWSEAGWGDSGSHTFPKMKSKFHDKAAKDKGFAKWENEKPRVH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SVRLQRATTSQATQTEPVWSEAGWGDSGSHTFPKMKSKFHDKAAKDKGFAKWENEKPRVH
              610       620       630       640       650       660

              670       680         
pF1KSD AGVDVVDRGTEFELDQDEGEETRQDGEDG
       :::::::::::::::::::::::::::::
XP_016 AGVDVVDRGTEFELDQDEGEETRQDGEDG
              670       680         

>>XP_016859251 (OMIM: 609531) PREDICTED: ras guanyl-rele  (689 aa)
 initn: 4677 init1: 4677 opt: 4677  Z-score: 4231.6  bits: 793.4 E(85289):    0
Smith-Waterman score: 4677; 100.0% identity (100.0% similar) in 689 aa overlap (1-689:1-689)

               10        20        30        40        50        60
pF1KSD MGSSGLGKAATLDELLCTCIEMFDDNGELDNSYLPRIVLLMHRWYLSSTELAEKLLCMYR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MGSSGLGKAATLDELLCTCIEMFDDNGELDNSYLPRIVLLMHRWYLSSTELAEKLLCMYR
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KSD NATGESCNEFRLKICYFMRYWILKFPAEFNLDLGLIRMTEEFREVASQLGYEKHVSLIDI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NATGESCNEFRLKICYFMRYWILKFPAEFNLDLGLIRMTEEFREVASQLGYEKHVSLIDI
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KSD SSIPSYDWMRRVTQRKKVSKKGKACLLFDHLEPIELAEHLTFLEHKSFRRISFTDYQSYV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SSIPSYDWMRRVTQRKKVSKKGKACLLFDHLEPIELAEHLTFLEHKSFRRISFTDYQSYV
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KSD IHGCLENNPTLERSIALFNGISKWVQLMVLSKPTPQQRAEVITKFINVAKKLLQLKNFNT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IHGCLENNPTLERSIALFNGISKWVQLMVLSKPTPQQRAEVITKFINVAKKLLQLKNFNT
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KSD LMAVVGGLSHSSISRLKETHSHLSSEVTKNWNEMTELVSSNGNYCNYRKAFADCDGFKIP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LMAVVGGLSHSSISRLKETHSHLSSEVTKNWNEMTELVSSNGNYCNYRKAFADCDGFKIP
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KSD ILGVHLKDLIAVHVIFPDWTEENKVNIVKMHQLSVTLSELVSLQNASHHLEPNMDLINLL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ILGVHLKDLIAVHVIFPDWTEENKVNIVKMHQLSVTLSELVSLQNASHHLEPNMDLINLL
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KSD TLSLDLYHTEDDIYKLSLVLEPRNSKSPTSPTTPNKPVVPLEWALGVMPKPDPTVINKHI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TLSLDLYHTEDDIYKLSLVLEPRNSKSPTSPTTPNKPVVPLEWALGVMPKPDPTVINKHI
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KSD RKLVESVFRNYDHDHDGYISQEDFESIAANFPFLDSFCVLDKDQDGLISKDEMMAYFLRA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RKLVESVFRNYDHDHDGYISQEDFESIAANFPFLDSFCVLDKDQDGLISKDEMMAYFLRA
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KSD KSQLHCKMGPGFIHNFQEMTYLKPTFCEHCAGFLWGIIKQGYKCKDCGANCHKQCKDLLV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KSQLHCKMGPGFIHNFQEMTYLKPTFCEHCAGFLWGIIKQGYKCKDCGANCHKQCKDLLV
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KSD LACRRFARAPSLSSGHGSLPGSPSLPPAQDEVFEFPGVTAGHRDLDSRAITLVTGSSRKI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LACRRFARAPSLSSGHGSLPGSPSLPPAQDEVFEFPGVTAGHRDLDSRAITLVTGSSRKI
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KSD SVRLQRATTSQATQTEPVWSEAGWGDSGSHTFPKMKSKFHDKAAKDKGFAKWENEKPRVH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SVRLQRATTSQATQTEPVWSEAGWGDSGSHTFPKMKSKFHDKAAKDKGFAKWENEKPRVH
              610       620       630       640       650       660

              670       680         
pF1KSD AGVDVVDRGTEFELDQDEGEETRQDGEDG
       :::::::::::::::::::::::::::::
XP_016 AGVDVVDRGTEFELDQDEGEETRQDGEDG
              670       680         

>>XP_005264303 (OMIM: 609531) PREDICTED: ras guanyl-rele  (689 aa)
 initn: 4677 init1: 4677 opt: 4677  Z-score: 4231.6  bits: 793.4 E(85289):    0
Smith-Waterman score: 4677; 100.0% identity (100.0% similar) in 689 aa overlap (1-689:1-689)

               10        20        30        40        50        60
pF1KSD MGSSGLGKAATLDELLCTCIEMFDDNGELDNSYLPRIVLLMHRWYLSSTELAEKLLCMYR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MGSSGLGKAATLDELLCTCIEMFDDNGELDNSYLPRIVLLMHRWYLSSTELAEKLLCMYR
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KSD NATGESCNEFRLKICYFMRYWILKFPAEFNLDLGLIRMTEEFREVASQLGYEKHVSLIDI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 NATGESCNEFRLKICYFMRYWILKFPAEFNLDLGLIRMTEEFREVASQLGYEKHVSLIDI
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KSD SSIPSYDWMRRVTQRKKVSKKGKACLLFDHLEPIELAEHLTFLEHKSFRRISFTDYQSYV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SSIPSYDWMRRVTQRKKVSKKGKACLLFDHLEPIELAEHLTFLEHKSFRRISFTDYQSYV
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KSD IHGCLENNPTLERSIALFNGISKWVQLMVLSKPTPQQRAEVITKFINVAKKLLQLKNFNT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 IHGCLENNPTLERSIALFNGISKWVQLMVLSKPTPQQRAEVITKFINVAKKLLQLKNFNT
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KSD LMAVVGGLSHSSISRLKETHSHLSSEVTKNWNEMTELVSSNGNYCNYRKAFADCDGFKIP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LMAVVGGLSHSSISRLKETHSHLSSEVTKNWNEMTELVSSNGNYCNYRKAFADCDGFKIP
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KSD ILGVHLKDLIAVHVIFPDWTEENKVNIVKMHQLSVTLSELVSLQNASHHLEPNMDLINLL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ILGVHLKDLIAVHVIFPDWTEENKVNIVKMHQLSVTLSELVSLQNASHHLEPNMDLINLL
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KSD TLSLDLYHTEDDIYKLSLVLEPRNSKSPTSPTTPNKPVVPLEWALGVMPKPDPTVINKHI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TLSLDLYHTEDDIYKLSLVLEPRNSKSPTSPTTPNKPVVPLEWALGVMPKPDPTVINKHI
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KSD RKLVESVFRNYDHDHDGYISQEDFESIAANFPFLDSFCVLDKDQDGLISKDEMMAYFLRA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RKLVESVFRNYDHDHDGYISQEDFESIAANFPFLDSFCVLDKDQDGLISKDEMMAYFLRA
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KSD KSQLHCKMGPGFIHNFQEMTYLKPTFCEHCAGFLWGIIKQGYKCKDCGANCHKQCKDLLV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KSQLHCKMGPGFIHNFQEMTYLKPTFCEHCAGFLWGIIKQGYKCKDCGANCHKQCKDLLV
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KSD LACRRFARAPSLSSGHGSLPGSPSLPPAQDEVFEFPGVTAGHRDLDSRAITLVTGSSRKI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LACRRFARAPSLSSGHGSLPGSPSLPPAQDEVFEFPGVTAGHRDLDSRAITLVTGSSRKI
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KSD SVRLQRATTSQATQTEPVWSEAGWGDSGSHTFPKMKSKFHDKAAKDKGFAKWENEKPRVH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SVRLQRATTSQATQTEPVWSEAGWGDSGSHTFPKMKSKFHDKAAKDKGFAKWENEKPRVH
              610       620       630       640       650       660

              670       680         
pF1KSD AGVDVVDRGTEFELDQDEGEETRQDGEDG
       :::::::::::::::::::::::::::::
XP_005 AGVDVVDRGTEFELDQDEGEETRQDGEDG
              670       680         

>>NP_056191 (OMIM: 609531) ras guanyl-releasing protein   (689 aa)
 initn: 4677 init1: 4677 opt: 4677  Z-score: 4231.6  bits: 793.4 E(85289):    0
Smith-Waterman score: 4677; 100.0% identity (100.0% similar) in 689 aa overlap (1-689:1-689)

               10        20        30        40        50        60
pF1KSD MGSSGLGKAATLDELLCTCIEMFDDNGELDNSYLPRIVLLMHRWYLSSTELAEKLLCMYR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 MGSSGLGKAATLDELLCTCIEMFDDNGELDNSYLPRIVLLMHRWYLSSTELAEKLLCMYR
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KSD NATGESCNEFRLKICYFMRYWILKFPAEFNLDLGLIRMTEEFREVASQLGYEKHVSLIDI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 NATGESCNEFRLKICYFMRYWILKFPAEFNLDLGLIRMTEEFREVASQLGYEKHVSLIDI
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KSD SSIPSYDWMRRVTQRKKVSKKGKACLLFDHLEPIELAEHLTFLEHKSFRRISFTDYQSYV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 SSIPSYDWMRRVTQRKKVSKKGKACLLFDHLEPIELAEHLTFLEHKSFRRISFTDYQSYV
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KSD IHGCLENNPTLERSIALFNGISKWVQLMVLSKPTPQQRAEVITKFINVAKKLLQLKNFNT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 IHGCLENNPTLERSIALFNGISKWVQLMVLSKPTPQQRAEVITKFINVAKKLLQLKNFNT
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KSD LMAVVGGLSHSSISRLKETHSHLSSEVTKNWNEMTELVSSNGNYCNYRKAFADCDGFKIP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 LMAVVGGLSHSSISRLKETHSHLSSEVTKNWNEMTELVSSNGNYCNYRKAFADCDGFKIP
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KSD ILGVHLKDLIAVHVIFPDWTEENKVNIVKMHQLSVTLSELVSLQNASHHLEPNMDLINLL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 ILGVHLKDLIAVHVIFPDWTEENKVNIVKMHQLSVTLSELVSLQNASHHLEPNMDLINLL
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KSD TLSLDLYHTEDDIYKLSLVLEPRNSKSPTSPTTPNKPVVPLEWALGVMPKPDPTVINKHI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 TLSLDLYHTEDDIYKLSLVLEPRNSKSPTSPTTPNKPVVPLEWALGVMPKPDPTVINKHI
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KSD RKLVESVFRNYDHDHDGYISQEDFESIAANFPFLDSFCVLDKDQDGLISKDEMMAYFLRA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 RKLVESVFRNYDHDHDGYISQEDFESIAANFPFLDSFCVLDKDQDGLISKDEMMAYFLRA
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KSD KSQLHCKMGPGFIHNFQEMTYLKPTFCEHCAGFLWGIIKQGYKCKDCGANCHKQCKDLLV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 KSQLHCKMGPGFIHNFQEMTYLKPTFCEHCAGFLWGIIKQGYKCKDCGANCHKQCKDLLV
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KSD LACRRFARAPSLSSGHGSLPGSPSLPPAQDEVFEFPGVTAGHRDLDSRAITLVTGSSRKI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 LACRRFARAPSLSSGHGSLPGSPSLPPAQDEVFEFPGVTAGHRDLDSRAITLVTGSSRKI
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KSD SVRLQRATTSQATQTEPVWSEAGWGDSGSHTFPKMKSKFHDKAAKDKGFAKWENEKPRVH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 SVRLQRATTSQATQTEPVWSEAGWGDSGSHTFPKMKSKFHDKAAKDKGFAKWENEKPRVH
              610       620       630       640       650       660

              670       680         
pF1KSD AGVDVVDRGTEFELDQDEGEETRQDGEDG
       :::::::::::::::::::::::::::::
NP_056 AGVDVVDRGTEFELDQDEGEETRQDGEDG
              670       680         

>>XP_011531048 (OMIM: 609531) PREDICTED: ras guanyl-rele  (690 aa)
 initn: 2558 init1: 2558 opt: 4665  Z-score: 4220.7  bits: 791.4 E(85289):    0
Smith-Waterman score: 4665; 99.9% identity (99.9% similar) in 690 aa overlap (1-689:1-690)

               10        20        30        40        50        60
pF1KSD MGSSGLGKAATLDELLCTCIEMFDDNGELDNSYLPRIVLLMHRWYLSSTELAEKLLCMYR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MGSSGLGKAATLDELLCTCIEMFDDNGELDNSYLPRIVLLMHRWYLSSTELAEKLLCMYR
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KSD NATGESCNEFRLKICYFMRYWILKFPAEFNLDLGLIRMTEEFREVASQLGYEKHVSLIDI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NATGESCNEFRLKICYFMRYWILKFPAEFNLDLGLIRMTEEFREVASQLGYEKHVSLIDI
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KSD SSIPSYDWMRRVTQRKKVSKKGKACLLFDHLEPIELAEHLTFLEHKSFRRISFTDYQSYV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SSIPSYDWMRRVTQRKKVSKKGKACLLFDHLEPIELAEHLTFLEHKSFRRISFTDYQSYV
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KSD IHGCLENNPTLERSIALFNGISKWVQLMVLSKPTPQQRAEVITKFINVAKKLLQLKNFNT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IHGCLENNPTLERSIALFNGISKWVQLMVLSKPTPQQRAEVITKFINVAKKLLQLKNFNT
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KSD LMAVVGGLSHSSISRLKETHSHLSSEVTKNWNEMTELVSSNGNYCNYRKAFADCDGFKIP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LMAVVGGLSHSSISRLKETHSHLSSEVTKNWNEMTELVSSNGNYCNYRKAFADCDGFKIP
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KSD ILGVHLKDLIAVHVIFPDWTEENKVNIVKMHQLSVTLSELVSLQNASHHLEPNMDLINLL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ILGVHLKDLIAVHVIFPDWTEENKVNIVKMHQLSVTLSELVSLQNASHHLEPNMDLINLL
              310       320       330       340       350       360

              370       380        390       400       410         
pF1KSD TLSLDLYHTEDDIYKLSLVLEPRNSKS-PTSPTTPNKPVVPLEWALGVMPKPDPTVINKH
       ::::::::::::::::::::::::::: ::::::::::::::::::::::::::::::::
XP_011 TLSLDLYHTEDDIYKLSLVLEPRNSKSQPTSPTTPNKPVVPLEWALGVMPKPDPTVINKH
              370       380       390       400       410       420

     420       430       440       450       460       470         
pF1KSD IRKLVESVFRNYDHDHDGYISQEDFESIAANFPFLDSFCVLDKDQDGLISKDEMMAYFLR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IRKLVESVFRNYDHDHDGYISQEDFESIAANFPFLDSFCVLDKDQDGLISKDEMMAYFLR
              430       440       450       460       470       480

     480       490       500       510       520       530         
pF1KSD AKSQLHCKMGPGFIHNFQEMTYLKPTFCEHCAGFLWGIIKQGYKCKDCGANCHKQCKDLL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AKSQLHCKMGPGFIHNFQEMTYLKPTFCEHCAGFLWGIIKQGYKCKDCGANCHKQCKDLL
              490       500       510       520       530       540

     540       550       560       570       580       590         
pF1KSD VLACRRFARAPSLSSGHGSLPGSPSLPPAQDEVFEFPGVTAGHRDLDSRAITLVTGSSRK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VLACRRFARAPSLSSGHGSLPGSPSLPPAQDEVFEFPGVTAGHRDLDSRAITLVTGSSRK
              550       560       570       580       590       600

     600       610       620       630       640       650         
pF1KSD ISVRLQRATTSQATQTEPVWSEAGWGDSGSHTFPKMKSKFHDKAAKDKGFAKWENEKPRV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ISVRLQRATTSQATQTEPVWSEAGWGDSGSHTFPKMKSKFHDKAAKDKGFAKWENEKPRV
              610       620       630       640       650       660

     660       670       680         
pF1KSD HAGVDVVDRGTEFELDQDEGEETRQDGEDG
       ::::::::::::::::::::::::::::::
XP_011 HAGVDVVDRGTEFELDQDEGEETRQDGEDG
              670       680       690

>>XP_016859248 (OMIM: 609531) PREDICTED: ras guanyl-rele  (690 aa)
 initn: 2558 init1: 2558 opt: 4665  Z-score: 4220.7  bits: 791.4 E(85289):    0
Smith-Waterman score: 4665; 99.9% identity (99.9% similar) in 690 aa overlap (1-689:1-690)

               10        20        30        40        50        60
pF1KSD MGSSGLGKAATLDELLCTCIEMFDDNGELDNSYLPRIVLLMHRWYLSSTELAEKLLCMYR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MGSSGLGKAATLDELLCTCIEMFDDNGELDNSYLPRIVLLMHRWYLSSTELAEKLLCMYR
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KSD NATGESCNEFRLKICYFMRYWILKFPAEFNLDLGLIRMTEEFREVASQLGYEKHVSLIDI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NATGESCNEFRLKICYFMRYWILKFPAEFNLDLGLIRMTEEFREVASQLGYEKHVSLIDI
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KSD SSIPSYDWMRRVTQRKKVSKKGKACLLFDHLEPIELAEHLTFLEHKSFRRISFTDYQSYV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SSIPSYDWMRRVTQRKKVSKKGKACLLFDHLEPIELAEHLTFLEHKSFRRISFTDYQSYV
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KSD IHGCLENNPTLERSIALFNGISKWVQLMVLSKPTPQQRAEVITKFINVAKKLLQLKNFNT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IHGCLENNPTLERSIALFNGISKWVQLMVLSKPTPQQRAEVITKFINVAKKLLQLKNFNT
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KSD LMAVVGGLSHSSISRLKETHSHLSSEVTKNWNEMTELVSSNGNYCNYRKAFADCDGFKIP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LMAVVGGLSHSSISRLKETHSHLSSEVTKNWNEMTELVSSNGNYCNYRKAFADCDGFKIP
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KSD ILGVHLKDLIAVHVIFPDWTEENKVNIVKMHQLSVTLSELVSLQNASHHLEPNMDLINLL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ILGVHLKDLIAVHVIFPDWTEENKVNIVKMHQLSVTLSELVSLQNASHHLEPNMDLINLL
              310       320       330       340       350       360

              370       380        390       400       410         
pF1KSD TLSLDLYHTEDDIYKLSLVLEPRNSKS-PTSPTTPNKPVVPLEWALGVMPKPDPTVINKH
       ::::::::::::::::::::::::::: ::::::::::::::::::::::::::::::::
XP_016 TLSLDLYHTEDDIYKLSLVLEPRNSKSQPTSPTTPNKPVVPLEWALGVMPKPDPTVINKH
              370       380       390       400       410       420

     420       430       440       450       460       470         
pF1KSD IRKLVESVFRNYDHDHDGYISQEDFESIAANFPFLDSFCVLDKDQDGLISKDEMMAYFLR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IRKLVESVFRNYDHDHDGYISQEDFESIAANFPFLDSFCVLDKDQDGLISKDEMMAYFLR
              430       440       450       460       470       480

     480       490       500       510       520       530         
pF1KSD AKSQLHCKMGPGFIHNFQEMTYLKPTFCEHCAGFLWGIIKQGYKCKDCGANCHKQCKDLL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AKSQLHCKMGPGFIHNFQEMTYLKPTFCEHCAGFLWGIIKQGYKCKDCGANCHKQCKDLL
              490       500       510       520       530       540

     540       550       560       570       580       590         
pF1KSD VLACRRFARAPSLSSGHGSLPGSPSLPPAQDEVFEFPGVTAGHRDLDSRAITLVTGSSRK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VLACRRFARAPSLSSGHGSLPGSPSLPPAQDEVFEFPGVTAGHRDLDSRAITLVTGSSRK
              550       560       570       580       590       600

     600       610       620       630       640       650         
pF1KSD ISVRLQRATTSQATQTEPVWSEAGWGDSGSHTFPKMKSKFHDKAAKDKGFAKWENEKPRV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ISVRLQRATTSQATQTEPVWSEAGWGDSGSHTFPKMKSKFHDKAAKDKGFAKWENEKPRV
              610       620       630       640       650       660

     660       670       680         
pF1KSD HAGVDVVDRGTEFELDQDEGEETRQDGEDG
       ::::::::::::::::::::::::::::::
XP_016 HAGVDVVDRGTEFELDQDEGEETRQDGEDG
              670       680       690

>>XP_011531049 (OMIM: 609531) PREDICTED: ras guanyl-rele  (690 aa)
 initn: 2558 init1: 2558 opt: 4665  Z-score: 4220.7  bits: 791.4 E(85289):    0
Smith-Waterman score: 4665; 99.9% identity (99.9% similar) in 690 aa overlap (1-689:1-690)

               10        20        30        40        50        60
pF1KSD MGSSGLGKAATLDELLCTCIEMFDDNGELDNSYLPRIVLLMHRWYLSSTELAEKLLCMYR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MGSSGLGKAATLDELLCTCIEMFDDNGELDNSYLPRIVLLMHRWYLSSTELAEKLLCMYR
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KSD NATGESCNEFRLKICYFMRYWILKFPAEFNLDLGLIRMTEEFREVASQLGYEKHVSLIDI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NATGESCNEFRLKICYFMRYWILKFPAEFNLDLGLIRMTEEFREVASQLGYEKHVSLIDI
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KSD SSIPSYDWMRRVTQRKKVSKKGKACLLFDHLEPIELAEHLTFLEHKSFRRISFTDYQSYV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SSIPSYDWMRRVTQRKKVSKKGKACLLFDHLEPIELAEHLTFLEHKSFRRISFTDYQSYV
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KSD IHGCLENNPTLERSIALFNGISKWVQLMVLSKPTPQQRAEVITKFINVAKKLLQLKNFNT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IHGCLENNPTLERSIALFNGISKWVQLMVLSKPTPQQRAEVITKFINVAKKLLQLKNFNT
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KSD LMAVVGGLSHSSISRLKETHSHLSSEVTKNWNEMTELVSSNGNYCNYRKAFADCDGFKIP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LMAVVGGLSHSSISRLKETHSHLSSEVTKNWNEMTELVSSNGNYCNYRKAFADCDGFKIP
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KSD ILGVHLKDLIAVHVIFPDWTEENKVNIVKMHQLSVTLSELVSLQNASHHLEPNMDLINLL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ILGVHLKDLIAVHVIFPDWTEENKVNIVKMHQLSVTLSELVSLQNASHHLEPNMDLINLL
              310       320       330       340       350       360

              370       380        390       400       410         
pF1KSD TLSLDLYHTEDDIYKLSLVLEPRNSKS-PTSPTTPNKPVVPLEWALGVMPKPDPTVINKH
       ::::::::::::::::::::::::::: ::::::::::::::::::::::::::::::::
XP_011 TLSLDLYHTEDDIYKLSLVLEPRNSKSQPTSPTTPNKPVVPLEWALGVMPKPDPTVINKH
              370       380       390       400       410       420

     420       430       440       450       460       470         
pF1KSD IRKLVESVFRNYDHDHDGYISQEDFESIAANFPFLDSFCVLDKDQDGLISKDEMMAYFLR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IRKLVESVFRNYDHDHDGYISQEDFESIAANFPFLDSFCVLDKDQDGLISKDEMMAYFLR
              430       440       450       460       470       480

     480       490       500       510       520       530         
pF1KSD AKSQLHCKMGPGFIHNFQEMTYLKPTFCEHCAGFLWGIIKQGYKCKDCGANCHKQCKDLL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AKSQLHCKMGPGFIHNFQEMTYLKPTFCEHCAGFLWGIIKQGYKCKDCGANCHKQCKDLL
              490       500       510       520       530       540

     540       550       560       570       580       590         
pF1KSD VLACRRFARAPSLSSGHGSLPGSPSLPPAQDEVFEFPGVTAGHRDLDSRAITLVTGSSRK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VLACRRFARAPSLSSGHGSLPGSPSLPPAQDEVFEFPGVTAGHRDLDSRAITLVTGSSRK
              550       560       570       580       590       600

     600       610       620       630       640       650         
pF1KSD ISVRLQRATTSQATQTEPVWSEAGWGDSGSHTFPKMKSKFHDKAAKDKGFAKWENEKPRV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ISVRLQRATTSQATQTEPVWSEAGWGDSGSHTFPKMKSKFHDKAAKDKGFAKWENEKPRV
              610       620       630       640       650       660

     660       670       680         
pF1KSD HAGVDVVDRGTEFELDQDEGEETRQDGEDG
       ::::::::::::::::::::::::::::::
XP_011 HAGVDVVDRGTEFELDQDEGEETRQDGEDG
              670       680       690

>>XP_011531050 (OMIM: 609531) PREDICTED: ras guanyl-rele  (690 aa)
 initn: 2558 init1: 2558 opt: 4665  Z-score: 4220.7  bits: 791.4 E(85289):    0
Smith-Waterman score: 4665; 99.9% identity (99.9% similar) in 690 aa overlap (1-689:1-690)

               10        20        30        40        50        60
pF1KSD MGSSGLGKAATLDELLCTCIEMFDDNGELDNSYLPRIVLLMHRWYLSSTELAEKLLCMYR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MGSSGLGKAATLDELLCTCIEMFDDNGELDNSYLPRIVLLMHRWYLSSTELAEKLLCMYR
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KSD NATGESCNEFRLKICYFMRYWILKFPAEFNLDLGLIRMTEEFREVASQLGYEKHVSLIDI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NATGESCNEFRLKICYFMRYWILKFPAEFNLDLGLIRMTEEFREVASQLGYEKHVSLIDI
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KSD SSIPSYDWMRRVTQRKKVSKKGKACLLFDHLEPIELAEHLTFLEHKSFRRISFTDYQSYV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SSIPSYDWMRRVTQRKKVSKKGKACLLFDHLEPIELAEHLTFLEHKSFRRISFTDYQSYV
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KSD IHGCLENNPTLERSIALFNGISKWVQLMVLSKPTPQQRAEVITKFINVAKKLLQLKNFNT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IHGCLENNPTLERSIALFNGISKWVQLMVLSKPTPQQRAEVITKFINVAKKLLQLKNFNT
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KSD LMAVVGGLSHSSISRLKETHSHLSSEVTKNWNEMTELVSSNGNYCNYRKAFADCDGFKIP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LMAVVGGLSHSSISRLKETHSHLSSEVTKNWNEMTELVSSNGNYCNYRKAFADCDGFKIP
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KSD ILGVHLKDLIAVHVIFPDWTEENKVNIVKMHQLSVTLSELVSLQNASHHLEPNMDLINLL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ILGVHLKDLIAVHVIFPDWTEENKVNIVKMHQLSVTLSELVSLQNASHHLEPNMDLINLL
              310       320       330       340       350       360

              370       380        390       400       410         
pF1KSD TLSLDLYHTEDDIYKLSLVLEPRNSKS-PTSPTTPNKPVVPLEWALGVMPKPDPTVINKH
       ::::::::::::::::::::::::::: ::::::::::::::::::::::::::::::::
XP_011 TLSLDLYHTEDDIYKLSLVLEPRNSKSQPTSPTTPNKPVVPLEWALGVMPKPDPTVINKH
              370       380       390       400       410       420

     420       430       440       450       460       470         
pF1KSD IRKLVESVFRNYDHDHDGYISQEDFESIAANFPFLDSFCVLDKDQDGLISKDEMMAYFLR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IRKLVESVFRNYDHDHDGYISQEDFESIAANFPFLDSFCVLDKDQDGLISKDEMMAYFLR
              430       440       450       460       470       480

     480       490       500       510       520       530         
pF1KSD AKSQLHCKMGPGFIHNFQEMTYLKPTFCEHCAGFLWGIIKQGYKCKDCGANCHKQCKDLL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AKSQLHCKMGPGFIHNFQEMTYLKPTFCEHCAGFLWGIIKQGYKCKDCGANCHKQCKDLL
              490       500       510       520       530       540

     540       550       560       570       580       590         
pF1KSD VLACRRFARAPSLSSGHGSLPGSPSLPPAQDEVFEFPGVTAGHRDLDSRAITLVTGSSRK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VLACRRFARAPSLSSGHGSLPGSPSLPPAQDEVFEFPGVTAGHRDLDSRAITLVTGSSRK
              550       560       570       580       590       600

     600       610       620       630       640       650         
pF1KSD ISVRLQRATTSQATQTEPVWSEAGWGDSGSHTFPKMKSKFHDKAAKDKGFAKWENEKPRV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ISVRLQRATTSQATQTEPVWSEAGWGDSGSHTFPKMKSKFHDKAAKDKGFAKWENEKPRV
              610       620       630       640       650       660

     660       670       680         
pF1KSD HAGVDVVDRGTEFELDQDEGEETRQDGEDG
       ::::::::::::::::::::::::::::::
XP_011 HAGVDVVDRGTEFELDQDEGEETRQDGEDG
              670       680       690

>>XP_016859250 (OMIM: 609531) PREDICTED: ras guanyl-rele  (690 aa)
 initn: 2558 init1: 2558 opt: 4665  Z-score: 4220.7  bits: 791.4 E(85289):    0
Smith-Waterman score: 4665; 99.9% identity (99.9% similar) in 690 aa overlap (1-689:1-690)

               10        20        30        40        50        60
pF1KSD MGSSGLGKAATLDELLCTCIEMFDDNGELDNSYLPRIVLLMHRWYLSSTELAEKLLCMYR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MGSSGLGKAATLDELLCTCIEMFDDNGELDNSYLPRIVLLMHRWYLSSTELAEKLLCMYR
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KSD NATGESCNEFRLKICYFMRYWILKFPAEFNLDLGLIRMTEEFREVASQLGYEKHVSLIDI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NATGESCNEFRLKICYFMRYWILKFPAEFNLDLGLIRMTEEFREVASQLGYEKHVSLIDI
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KSD SSIPSYDWMRRVTQRKKVSKKGKACLLFDHLEPIELAEHLTFLEHKSFRRISFTDYQSYV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SSIPSYDWMRRVTQRKKVSKKGKACLLFDHLEPIELAEHLTFLEHKSFRRISFTDYQSYV
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KSD IHGCLENNPTLERSIALFNGISKWVQLMVLSKPTPQQRAEVITKFINVAKKLLQLKNFNT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IHGCLENNPTLERSIALFNGISKWVQLMVLSKPTPQQRAEVITKFINVAKKLLQLKNFNT
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KSD LMAVVGGLSHSSISRLKETHSHLSSEVTKNWNEMTELVSSNGNYCNYRKAFADCDGFKIP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LMAVVGGLSHSSISRLKETHSHLSSEVTKNWNEMTELVSSNGNYCNYRKAFADCDGFKIP
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KSD ILGVHLKDLIAVHVIFPDWTEENKVNIVKMHQLSVTLSELVSLQNASHHLEPNMDLINLL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ILGVHLKDLIAVHVIFPDWTEENKVNIVKMHQLSVTLSELVSLQNASHHLEPNMDLINLL
              310       320       330       340       350       360

              370       380        390       400       410         
pF1KSD TLSLDLYHTEDDIYKLSLVLEPRNSKS-PTSPTTPNKPVVPLEWALGVMPKPDPTVINKH
       ::::::::::::::::::::::::::: ::::::::::::::::::::::::::::::::
XP_016 TLSLDLYHTEDDIYKLSLVLEPRNSKSQPTSPTTPNKPVVPLEWALGVMPKPDPTVINKH
              370       380       390       400       410       420

     420       430       440       450       460       470         
pF1KSD IRKLVESVFRNYDHDHDGYISQEDFESIAANFPFLDSFCVLDKDQDGLISKDEMMAYFLR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IRKLVESVFRNYDHDHDGYISQEDFESIAANFPFLDSFCVLDKDQDGLISKDEMMAYFLR
              430       440       450       460       470       480

     480       490       500       510       520       530         
pF1KSD AKSQLHCKMGPGFIHNFQEMTYLKPTFCEHCAGFLWGIIKQGYKCKDCGANCHKQCKDLL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AKSQLHCKMGPGFIHNFQEMTYLKPTFCEHCAGFLWGIIKQGYKCKDCGANCHKQCKDLL
              490       500       510       520       530       540

     540       550       560       570       580       590         
pF1KSD VLACRRFARAPSLSSGHGSLPGSPSLPPAQDEVFEFPGVTAGHRDLDSRAITLVTGSSRK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VLACRRFARAPSLSSGHGSLPGSPSLPPAQDEVFEFPGVTAGHRDLDSRAITLVTGSSRK
              550       560       570       580       590       600

     600       610       620       630       640       650         
pF1KSD ISVRLQRATTSQATQTEPVWSEAGWGDSGSHTFPKMKSKFHDKAAKDKGFAKWENEKPRV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ISVRLQRATTSQATQTEPVWSEAGWGDSGSHTFPKMKSKFHDKAAKDKGFAKWENEKPRV
              610       620       630       640       650       660

     660       670       680         
pF1KSD HAGVDVVDRGTEFELDQDEGEETRQDGEDG
       ::::::::::::::::::::::::::::::
XP_016 HAGVDVVDRGTEFELDQDEGEETRQDGEDG
              670       680       690

>>NP_001132960 (OMIM: 609531) ras guanyl-releasing prote  (690 aa)
 initn: 2558 init1: 2558 opt: 4665  Z-score: 4220.7  bits: 791.4 E(85289):    0
Smith-Waterman score: 4665; 99.9% identity (99.9% similar) in 690 aa overlap (1-689:1-690)

               10        20        30        40        50        60
pF1KSD MGSSGLGKAATLDELLCTCIEMFDDNGELDNSYLPRIVLLMHRWYLSSTELAEKLLCMYR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MGSSGLGKAATLDELLCTCIEMFDDNGELDNSYLPRIVLLMHRWYLSSTELAEKLLCMYR
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KSD NATGESCNEFRLKICYFMRYWILKFPAEFNLDLGLIRMTEEFREVASQLGYEKHVSLIDI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NATGESCNEFRLKICYFMRYWILKFPAEFNLDLGLIRMTEEFREVASQLGYEKHVSLIDI
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KSD SSIPSYDWMRRVTQRKKVSKKGKACLLFDHLEPIELAEHLTFLEHKSFRRISFTDYQSYV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SSIPSYDWMRRVTQRKKVSKKGKACLLFDHLEPIELAEHLTFLEHKSFRRISFTDYQSYV
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KSD IHGCLENNPTLERSIALFNGISKWVQLMVLSKPTPQQRAEVITKFINVAKKLLQLKNFNT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IHGCLENNPTLERSIALFNGISKWVQLMVLSKPTPQQRAEVITKFINVAKKLLQLKNFNT
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KSD LMAVVGGLSHSSISRLKETHSHLSSEVTKNWNEMTELVSSNGNYCNYRKAFADCDGFKIP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LMAVVGGLSHSSISRLKETHSHLSSEVTKNWNEMTELVSSNGNYCNYRKAFADCDGFKIP
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KSD ILGVHLKDLIAVHVIFPDWTEENKVNIVKMHQLSVTLSELVSLQNASHHLEPNMDLINLL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ILGVHLKDLIAVHVIFPDWTEENKVNIVKMHQLSVTLSELVSLQNASHHLEPNMDLINLL
              310       320       330       340       350       360

              370       380        390       400       410         
pF1KSD TLSLDLYHTEDDIYKLSLVLEPRNSKS-PTSPTTPNKPVVPLEWALGVMPKPDPTVINKH
       ::::::::::::::::::::::::::: ::::::::::::::::::::::::::::::::
NP_001 TLSLDLYHTEDDIYKLSLVLEPRNSKSQPTSPTTPNKPVVPLEWALGVMPKPDPTVINKH
              370       380       390       400       410       420

     420       430       440       450       460       470         
pF1KSD IRKLVESVFRNYDHDHDGYISQEDFESIAANFPFLDSFCVLDKDQDGLISKDEMMAYFLR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IRKLVESVFRNYDHDHDGYISQEDFESIAANFPFLDSFCVLDKDQDGLISKDEMMAYFLR
              430       440       450       460       470       480

     480       490       500       510       520       530         
pF1KSD AKSQLHCKMGPGFIHNFQEMTYLKPTFCEHCAGFLWGIIKQGYKCKDCGANCHKQCKDLL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AKSQLHCKMGPGFIHNFQEMTYLKPTFCEHCAGFLWGIIKQGYKCKDCGANCHKQCKDLL
              490       500       510       520       530       540

     540       550       560       570       580       590         
pF1KSD VLACRRFARAPSLSSGHGSLPGSPSLPPAQDEVFEFPGVTAGHRDLDSRAITLVTGSSRK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VLACRRFARAPSLSSGHGSLPGSPSLPPAQDEVFEFPGVTAGHRDLDSRAITLVTGSSRK
              550       560       570       580       590       600

     600       610       620       630       640       650         
pF1KSD ISVRLQRATTSQATQTEPVWSEAGWGDSGSHTFPKMKSKFHDKAAKDKGFAKWENEKPRV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ISVRLQRATTSQATQTEPVWSEAGWGDSGSHTFPKMKSKFHDKAAKDKGFAKWENEKPRV
              610       620       630       640       650       660

     660       670       680         
pF1KSD HAGVDVVDRGTEFELDQDEGEETRQDGEDG
       ::::::::::::::::::::::::::::::
NP_001 HAGVDVVDRGTEFELDQDEGEETRQDGEDG
              670       680       690




689 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Thu Nov  3 03:43:57 2016 done: Thu Nov  3 03:43:59 2016
 Total Scan time: 10.050 Total Display time:  0.230

Function used was FASTA [36.3.4 Apr, 2011]
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