Result of FASTA (omim) for pF1KSDA0083
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KSDA0083, 1060 aa
  1>>>pF1KSDA0083 1060 - 1060 aa - 1060 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 5.7793+/-0.000568; mu= 19.4674+/- 0.035
 mean_var=77.0506+/-15.440, 0's: 0 Z-trim(107.1): 57  B-trim: 0 in 0/49
 Lambda= 0.146112
 statistics sampled from 15075 (15129) to 15075 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.502), E-opt: 0.2 (0.177), width:  16
 Scan time: 14.170

The best scores are:                                      opt bits E(85289)
NP_001073918 (OMIM: 601810,615156,615807) DNA repl (1060) 6979 1482.0       0
XP_006717743 (OMIM: 601810,615156,615807) PREDICTE (1090) 6979 1482.0       0
XP_016871288 (OMIM: 601810,615156,615807) PREDICTE ( 836) 5498 1169.7       0
XP_011537719 (OMIM: 601810,615156,615807) PREDICTE ( 700) 4604 981.2       0
XP_005261980 (OMIM: 605794) PREDICTED: RNA helicas (1191)  380 91.0 4.5e-17
NP_061868 (OMIM: 605794) RNA helicase Mov10l1 isof (1211)  380 91.0 4.5e-17
NP_001157577 (OMIM: 605794) RNA helicase Mov10l1 i (1165)  372 89.3 1.4e-16
NP_001157578 (OMIM: 605794) RNA helicase Mov10l1 i ( 338)  310 75.9 4.3e-13
NP_002902 (OMIM: 601430) regulator of nonsense tra (1118)  299 73.9 5.8e-12
XP_016882595 (OMIM: 601430) PREDICTED: regulator o (1126)  299 73.9 5.9e-12
NP_001284478 (OMIM: 601430) regulator of nonsense  (1129)  299 73.9 5.9e-12
XP_016882594 (OMIM: 601430) PREDICTED: regulator o (1137)  299 73.9 5.9e-12
NP_001157576 (OMIM: 605794) RNA helicase Mov10l1 i (1165)  296 73.3 9.4e-12
XP_011543296 (OMIM: 600502,604320,616155) PREDICTE ( 582)  262 65.9 7.5e-10
XP_005274032 (OMIM: 600502,604320,616155) PREDICTE ( 617)  262 65.9 7.9e-10
XP_005274031 (OMIM: 600502,604320,616155) PREDICTE ( 656)  262 66.0 8.3e-10
XP_016873158 (OMIM: 600502,604320,616155) PREDICTE ( 656)  262 66.0 8.3e-10
XP_016873159 (OMIM: 600502,604320,616155) PREDICTE ( 656)  262 66.0 8.3e-10
XP_016873160 (OMIM: 600502,604320,616155) PREDICTE ( 546)  259 65.3 1.1e-09
NP_002171 (OMIM: 600502,604320,616155) DNA-binding ( 993)  262 66.1 1.2e-09
XP_016884324 (OMIM: 605794) PREDICTED: RNA helicas ( 730)  242 61.8 1.7e-08
XP_011529005 (OMIM: 605794) PREDICTED: RNA helicas ( 730)  242 61.8 1.7e-08
XP_016884325 (OMIM: 605794) PREDICTED: RNA helicas ( 730)  242 61.8 1.7e-08
XP_011529004 (OMIM: 605794) PREDICTED: RNA helicas (1015)  242 61.8 2.2e-08
XP_011529003 (OMIM: 605794) PREDICTED: RNA helicas (1074)  242 61.9 2.3e-08
XP_011529002 (OMIM: 605794) PREDICTED: RNA helicas (1204)  242 61.9 2.6e-08
XP_011529001 (OMIM: 605794) PREDICTED: RNA helicas (1204)  242 61.9 2.6e-08
XP_011529000 (OMIM: 605794) PREDICTED: RNA helicas (1209)  242 61.9 2.6e-08
XP_016884322 (OMIM: 605794) PREDICTED: RNA helicas (1210)  242 61.9 2.6e-08
XP_011528999 (OMIM: 605794) PREDICTED: RNA helicas (1236)  242 61.9 2.6e-08
XP_011528998 (OMIM: 605794) PREDICTED: RNA helicas (1256)  242 61.9 2.7e-08
XP_016869985 (OMIM: 602433,606002,608465) PREDICTE ( 857)  235 60.3 5.4e-08
XP_005272228 (OMIM: 602433,606002,608465) PREDICTE (2706)  235 60.6 1.4e-07
XP_005272230 (OMIM: 602433,606002,608465) PREDICTE (2706)  235 60.6 1.4e-07
XP_011516706 (OMIM: 602433,606002,608465) PREDICTE (2706)  235 60.6 1.4e-07
XP_005272229 (OMIM: 602433,606002,608465) PREDICTE (2706)  235 60.6 1.4e-07
XP_011516707 (OMIM: 602433,606002,608465) PREDICTE (2706)  235 60.6 1.4e-07
XP_016869986 (OMIM: 602433,606002,608465) PREDICTE ( 828)  223 57.8   3e-07
XP_016869984 (OMIM: 602433,606002,608465) PREDICTE (2677)  223 58.1 8.1e-07
NP_055861 (OMIM: 602433,606002,608465) probable he (2677)  223 58.1 8.1e-07
XP_016880967 (OMIM: 606699) PREDICTED: probable he (1551)  207 54.6 5.3e-06
XP_006722279 (OMIM: 606699) PREDICTED: probable he (1578)  207 54.6 5.4e-06
XP_016880966 (OMIM: 606699) PREDICTED: probable he (1707)  207 54.6 5.7e-06
XP_006722278 (OMIM: 606699) PREDICTED: probable he (1735)  207 54.6 5.8e-06
NP_055692 (OMIM: 606699) probable helicase with zi (1942)  207 54.6 6.4e-06
NP_001317376 (OMIM: 606699) probable helicase with (1943)  207 54.6 6.4e-06
XP_005257945 (OMIM: 606699) PREDICTED: probable he (1969)  207 54.6 6.5e-06
XP_006722277 (OMIM: 606699) PREDICTED: probable he (1970)  207 54.6 6.5e-06
XP_011523846 (OMIM: 606699) PREDICTED: probable he (1970)  207 54.6 6.5e-06
NP_208384 (OMIM: 611265) helicase with zinc finger (2080)  198 52.7 2.5e-05


>>NP_001073918 (OMIM: 601810,615156,615807) DNA replicat  (1060 aa)
 initn: 6979 init1: 6979 opt: 6979  Z-score: 7946.1  bits: 1482.0 E(85289):    0
Smith-Waterman score: 6979; 100.0% identity (100.0% similar) in 1060 aa overlap (1-1060:1-1060)

               10        20        30        40        50        60
pF1KSD MEQLNELELLMEKSFWEEAELPAELFQKKVVASFPRTVLSTGMDNRYLVLAVNTVQNKEG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MEQLNELELLMEKSFWEEAELPAELFQKKVVASFPRTVLSTGMDNRYLVLAVNTVQNKEG
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KSD NCEKRLVITASQSLENKELCILRNDWCSVPVEPGDIIHLEGDCTSDTWIIDKDFGYLILY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NCEKRLVITASQSLENKELCILRNDWCSVPVEPGDIIHLEGDCTSDTWIIDKDFGYLILY
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KSD PDMLISGTSIASSIRCMRRAVLSETFRSSDPATRQMLIGTVLHEVFQKAINNSFAPEKLQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PDMLISGTSIASSIRCMRRAVLSETFRSSDPATRQMLIGTVLHEVFQKAINNSFAPEKLQ
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KSD ELAFQTIQEIRHLKEMYRLNLSQDEIKQEVEDYLPSFCKWAGDFMHKNTSTDFPQMQLSL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ELAFQTIQEIRHLKEMYRLNLSQDEIKQEVEDYLPSFCKWAGDFMHKNTSTDFPQMQLSL
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KSD PSDNSKDNSTCNIEVVKPMDIEESIWSPRFGLKGKIDVTVGVKIHRGYKTKYKIMPLELK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PSDNSKDNSTCNIEVVKPMDIEESIWSPRFGLKGKIDVTVGVKIHRGYKTKYKIMPLELK
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KSD TGKESNSIEHRSQVVLYTLLSQERRADPEAGLLLYLKTGQMYPVPANHLDKRELLKLRNQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TGKESNSIEHRSQVVLYTLLSQERRADPEAGLLLYLKTGQMYPVPANHLDKRELLKLRNQ
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KSD MAFSLFHRISKSATRQKTQLASLPQIIEEEKTCKYCSQIGNCALYSRAVEQQMDCSSVPI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MAFSLFHRISKSATRQKTQLASLPQIIEEEKTCKYCSQIGNCALYSRAVEQQMDCSSVPI
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KSD VMLPKIEEETQHLKQTHLEYFSLWCLMLTLESQSKDNKKNHQNIWLMPASEMEKSGSCIG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VMLPKIEEETQHLKQTHLEYFSLWCLMLTLESQSKDNKKNHQNIWLMPASEMEKSGSCIG
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KSD NLIRMEHVKIVCDGQYLHNFQCKHGAIPVTNLMAGDRVIVSGEERSLFALSRGYVKEINM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NLIRMEHVKIVCDGQYLHNFQCKHGAIPVTNLMAGDRVIVSGEERSLFALSRGYVKEINM
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KSD TTVTCLLDRNLSVLPESTLFRLDQEEKNCDIDTPLGNLSKLMENTFVSKKLRDLIIDFRE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TTVTCLLDRNLSVLPESTLFRLDQEEKNCDIDTPLGNLSKLMENTFVSKKLRDLIIDFRE
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KSD PQFISYLSSVLPHDAKDTVACILKGLNKPQRQAMKKVLLSKDYTLIVGMPGTGKTTTICT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PQFISYLSSVLPHDAKDTVACILKGLNKPQRQAMKKVLLSKDYTLIVGMPGTGKTTTICT
              610       620       630       640       650       660

              670       680       690       700       710       720
pF1KSD LVRILYACGFSVLLTSYTHSAVDNILLKLAKFKIGFLRLGQIQKVHPAIQQFTEQEICRS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LVRILYACGFSVLLTSYTHSAVDNILLKLAKFKIGFLRLGQIQKVHPAIQQFTEQEICRS
              670       680       690       700       710       720

              730       740       750       760       770       780
pF1KSD KSIKSLALLEELYNSQLIVATTCMGINHPIFSRKIFDFCIVDEASQISQPICLGPLFFSR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KSIKSLALLEELYNSQLIVATTCMGINHPIFSRKIFDFCIVDEASQISQPICLGPLFFSR
              730       740       750       760       770       780

              790       800       810       820       830       840
pF1KSD RFVLVGDHQQLPPLVLNREARALGMSESLFKRLEQNKSAVVQLTVQYRMNSKIMSLSNKL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RFVLVGDHQQLPPLVLNREARALGMSESLFKRLEQNKSAVVQLTVQYRMNSKIMSLSNKL
              790       800       810       820       830       840

              850       860       870       880       890       900
pF1KSD TYEGKLECGSDKVANAVINLRHFKDVKLELEFYADYSDNPWLMGVFEPNNPVCFLNTDKV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TYEGKLECGSDKVANAVINLRHFKDVKLELEFYADYSDNPWLMGVFEPNNPVCFLNTDKV
              850       860       870       880       890       900

              910       920       930       940       950       960
pF1KSD PAPEQVEKGGVSNVTEAKLIVFLTSIFVKAGCSPSDIGIIAPYRQQLKIINDLLARSIGM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PAPEQVEKGGVSNVTEAKLIVFLTSIFVKAGCSPSDIGIIAPYRQQLKIINDLLARSIGM
              910       920       930       940       950       960

              970       980       990      1000      1010      1020
pF1KSD VEVNTVDKYQGRDKSIVLVSFVRSNKDGTVGELLKDWRRLNVAITRAKHKLILLGCVPSL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VEVNTVDKYQGRDKSIVLVSFVRSNKDGTVGELLKDWRRLNVAITRAKHKLILLGCVPSL
              970       980       990      1000      1010      1020

             1030      1040      1050      1060
pF1KSD NCYPPLEKLLNHLNSEKLIIDLPSREHESLCHILGDFQRE
       ::::::::::::::::::::::::::::::::::::::::
NP_001 NCYPPLEKLLNHLNSEKLIIDLPSREHESLCHILGDFQRE
             1030      1040      1050      1060

>>XP_006717743 (OMIM: 601810,615156,615807) PREDICTED: D  (1090 aa)
 initn: 6979 init1: 6979 opt: 6979  Z-score: 7946.0  bits: 1482.0 E(85289):    0
Smith-Waterman score: 6979; 100.0% identity (100.0% similar) in 1060 aa overlap (1-1060:31-1090)

                                             10        20        30
pF1KSD                               MEQLNELELLMEKSFWEEAELPAELFQKKV
                                     ::::::::::::::::::::::::::::::
XP_006 MKTPCIPSPKQGSKGRGQSPAAQFAIPASRMEQLNELELLMEKSFWEEAELPAELFQKKV
               10        20        30        40        50        60

               40        50        60        70        80        90
pF1KSD VASFPRTVLSTGMDNRYLVLAVNTVQNKEGNCEKRLVITASQSLENKELCILRNDWCSVP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 VASFPRTVLSTGMDNRYLVLAVNTVQNKEGNCEKRLVITASQSLENKELCILRNDWCSVP
               70        80        90       100       110       120

              100       110       120       130       140       150
pF1KSD VEPGDIIHLEGDCTSDTWIIDKDFGYLILYPDMLISGTSIASSIRCMRRAVLSETFRSSD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 VEPGDIIHLEGDCTSDTWIIDKDFGYLILYPDMLISGTSIASSIRCMRRAVLSETFRSSD
              130       140       150       160       170       180

              160       170       180       190       200       210
pF1KSD PATRQMLIGTVLHEVFQKAINNSFAPEKLQELAFQTIQEIRHLKEMYRLNLSQDEIKQEV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 PATRQMLIGTVLHEVFQKAINNSFAPEKLQELAFQTIQEIRHLKEMYRLNLSQDEIKQEV
              190       200       210       220       230       240

              220       230       240       250       260       270
pF1KSD EDYLPSFCKWAGDFMHKNTSTDFPQMQLSLPSDNSKDNSTCNIEVVKPMDIEESIWSPRF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 EDYLPSFCKWAGDFMHKNTSTDFPQMQLSLPSDNSKDNSTCNIEVVKPMDIEESIWSPRF
              250       260       270       280       290       300

              280       290       300       310       320       330
pF1KSD GLKGKIDVTVGVKIHRGYKTKYKIMPLELKTGKESNSIEHRSQVVLYTLLSQERRADPEA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 GLKGKIDVTVGVKIHRGYKTKYKIMPLELKTGKESNSIEHRSQVVLYTLLSQERRADPEA
              310       320       330       340       350       360

              340       350       360       370       380       390
pF1KSD GLLLYLKTGQMYPVPANHLDKRELLKLRNQMAFSLFHRISKSATRQKTQLASLPQIIEEE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 GLLLYLKTGQMYPVPANHLDKRELLKLRNQMAFSLFHRISKSATRQKTQLASLPQIIEEE
              370       380       390       400       410       420

              400       410       420       430       440       450
pF1KSD KTCKYCSQIGNCALYSRAVEQQMDCSSVPIVMLPKIEEETQHLKQTHLEYFSLWCLMLTL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 KTCKYCSQIGNCALYSRAVEQQMDCSSVPIVMLPKIEEETQHLKQTHLEYFSLWCLMLTL
              430       440       450       460       470       480

              460       470       480       490       500       510
pF1KSD ESQSKDNKKNHQNIWLMPASEMEKSGSCIGNLIRMEHVKIVCDGQYLHNFQCKHGAIPVT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 ESQSKDNKKNHQNIWLMPASEMEKSGSCIGNLIRMEHVKIVCDGQYLHNFQCKHGAIPVT
              490       500       510       520       530       540

              520       530       540       550       560       570
pF1KSD NLMAGDRVIVSGEERSLFALSRGYVKEINMTTVTCLLDRNLSVLPESTLFRLDQEEKNCD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 NLMAGDRVIVSGEERSLFALSRGYVKEINMTTVTCLLDRNLSVLPESTLFRLDQEEKNCD
              550       560       570       580       590       600

              580       590       600       610       620       630
pF1KSD IDTPLGNLSKLMENTFVSKKLRDLIIDFREPQFISYLSSVLPHDAKDTVACILKGLNKPQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 IDTPLGNLSKLMENTFVSKKLRDLIIDFREPQFISYLSSVLPHDAKDTVACILKGLNKPQ
              610       620       630       640       650       660

              640       650       660       670       680       690
pF1KSD RQAMKKVLLSKDYTLIVGMPGTGKTTTICTLVRILYACGFSVLLTSYTHSAVDNILLKLA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 RQAMKKVLLSKDYTLIVGMPGTGKTTTICTLVRILYACGFSVLLTSYTHSAVDNILLKLA
              670       680       690       700       710       720

              700       710       720       730       740       750
pF1KSD KFKIGFLRLGQIQKVHPAIQQFTEQEICRSKSIKSLALLEELYNSQLIVATTCMGINHPI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 KFKIGFLRLGQIQKVHPAIQQFTEQEICRSKSIKSLALLEELYNSQLIVATTCMGINHPI
              730       740       750       760       770       780

              760       770       780       790       800       810
pF1KSD FSRKIFDFCIVDEASQISQPICLGPLFFSRRFVLVGDHQQLPPLVLNREARALGMSESLF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 FSRKIFDFCIVDEASQISQPICLGPLFFSRRFVLVGDHQQLPPLVLNREARALGMSESLF
              790       800       810       820       830       840

              820       830       840       850       860       870
pF1KSD KRLEQNKSAVVQLTVQYRMNSKIMSLSNKLTYEGKLECGSDKVANAVINLRHFKDVKLEL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 KRLEQNKSAVVQLTVQYRMNSKIMSLSNKLTYEGKLECGSDKVANAVINLRHFKDVKLEL
              850       860       870       880       890       900

              880       890       900       910       920       930
pF1KSD EFYADYSDNPWLMGVFEPNNPVCFLNTDKVPAPEQVEKGGVSNVTEAKLIVFLTSIFVKA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 EFYADYSDNPWLMGVFEPNNPVCFLNTDKVPAPEQVEKGGVSNVTEAKLIVFLTSIFVKA
              910       920       930       940       950       960

              940       950       960       970       980       990
pF1KSD GCSPSDIGIIAPYRQQLKIINDLLARSIGMVEVNTVDKYQGRDKSIVLVSFVRSNKDGTV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 GCSPSDIGIIAPYRQQLKIINDLLARSIGMVEVNTVDKYQGRDKSIVLVSFVRSNKDGTV
              970       980       990      1000      1010      1020

             1000      1010      1020      1030      1040      1050
pF1KSD GELLKDWRRLNVAITRAKHKLILLGCVPSLNCYPPLEKLLNHLNSEKLIIDLPSREHESL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 GELLKDWRRLNVAITRAKHKLILLGCVPSLNCYPPLEKLLNHLNSEKLIIDLPSREHESL
             1030      1040      1050      1060      1070      1080

             1060
pF1KSD CHILGDFQRE
       ::::::::::
XP_006 CHILGDFQRE
             1090

>>XP_016871288 (OMIM: 601810,615156,615807) PREDICTED: D  (836 aa)
 initn: 5498 init1: 5498 opt: 5498  Z-score: 6260.5  bits: 1169.7 E(85289):    0
Smith-Waterman score: 5498; 100.0% identity (100.0% similar) in 836 aa overlap (225-1060:1-836)

          200       210       220       230       240       250    
pF1KSD EMYRLNLSQDEIKQEVEDYLPSFCKWAGDFMHKNTSTDFPQMQLSLPSDNSKDNSTCNIE
                                     ::::::::::::::::::::::::::::::
XP_016                               MHKNTSTDFPQMQLSLPSDNSKDNSTCNIE
                                             10        20        30

          260       270       280       290       300       310    
pF1KSD VVKPMDIEESIWSPRFGLKGKIDVTVGVKIHRGYKTKYKIMPLELKTGKESNSIEHRSQV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VVKPMDIEESIWSPRFGLKGKIDVTVGVKIHRGYKTKYKIMPLELKTGKESNSIEHRSQV
               40        50        60        70        80        90

          320       330       340       350       360       370    
pF1KSD VLYTLLSQERRADPEAGLLLYLKTGQMYPVPANHLDKRELLKLRNQMAFSLFHRISKSAT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VLYTLLSQERRADPEAGLLLYLKTGQMYPVPANHLDKRELLKLRNQMAFSLFHRISKSAT
              100       110       120       130       140       150

          380       390       400       410       420       430    
pF1KSD RQKTQLASLPQIIEEEKTCKYCSQIGNCALYSRAVEQQMDCSSVPIVMLPKIEEETQHLK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RQKTQLASLPQIIEEEKTCKYCSQIGNCALYSRAVEQQMDCSSVPIVMLPKIEEETQHLK
              160       170       180       190       200       210

          440       450       460       470       480       490    
pF1KSD QTHLEYFSLWCLMLTLESQSKDNKKNHQNIWLMPASEMEKSGSCIGNLIRMEHVKIVCDG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QTHLEYFSLWCLMLTLESQSKDNKKNHQNIWLMPASEMEKSGSCIGNLIRMEHVKIVCDG
              220       230       240       250       260       270

          500       510       520       530       540       550    
pF1KSD QYLHNFQCKHGAIPVTNLMAGDRVIVSGEERSLFALSRGYVKEINMTTVTCLLDRNLSVL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QYLHNFQCKHGAIPVTNLMAGDRVIVSGEERSLFALSRGYVKEINMTTVTCLLDRNLSVL
              280       290       300       310       320       330

          560       570       580       590       600       610    
pF1KSD PESTLFRLDQEEKNCDIDTPLGNLSKLMENTFVSKKLRDLIIDFREPQFISYLSSVLPHD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PESTLFRLDQEEKNCDIDTPLGNLSKLMENTFVSKKLRDLIIDFREPQFISYLSSVLPHD
              340       350       360       370       380       390

          620       630       640       650       660       670    
pF1KSD AKDTVACILKGLNKPQRQAMKKVLLSKDYTLIVGMPGTGKTTTICTLVRILYACGFSVLL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AKDTVACILKGLNKPQRQAMKKVLLSKDYTLIVGMPGTGKTTTICTLVRILYACGFSVLL
              400       410       420       430       440       450

          680       690       700       710       720       730    
pF1KSD TSYTHSAVDNILLKLAKFKIGFLRLGQIQKVHPAIQQFTEQEICRSKSIKSLALLEELYN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TSYTHSAVDNILLKLAKFKIGFLRLGQIQKVHPAIQQFTEQEICRSKSIKSLALLEELYN
              460       470       480       490       500       510

          740       750       760       770       780       790    
pF1KSD SQLIVATTCMGINHPIFSRKIFDFCIVDEASQISQPICLGPLFFSRRFVLVGDHQQLPPL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SQLIVATTCMGINHPIFSRKIFDFCIVDEASQISQPICLGPLFFSRRFVLVGDHQQLPPL
              520       530       540       550       560       570

          800       810       820       830       840       850    
pF1KSD VLNREARALGMSESLFKRLEQNKSAVVQLTVQYRMNSKIMSLSNKLTYEGKLECGSDKVA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VLNREARALGMSESLFKRLEQNKSAVVQLTVQYRMNSKIMSLSNKLTYEGKLECGSDKVA
              580       590       600       610       620       630

          860       870       880       890       900       910    
pF1KSD NAVINLRHFKDVKLELEFYADYSDNPWLMGVFEPNNPVCFLNTDKVPAPEQVEKGGVSNV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NAVINLRHFKDVKLELEFYADYSDNPWLMGVFEPNNPVCFLNTDKVPAPEQVEKGGVSNV
              640       650       660       670       680       690

          920       930       940       950       960       970    
pF1KSD TEAKLIVFLTSIFVKAGCSPSDIGIIAPYRQQLKIINDLLARSIGMVEVNTVDKYQGRDK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TEAKLIVFLTSIFVKAGCSPSDIGIIAPYRQQLKIINDLLARSIGMVEVNTVDKYQGRDK
              700       710       720       730       740       750

          980       990      1000      1010      1020      1030    
pF1KSD SIVLVSFVRSNKDGTVGELLKDWRRLNVAITRAKHKLILLGCVPSLNCYPPLEKLLNHLN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SIVLVSFVRSNKDGTVGELLKDWRRLNVAITRAKHKLILLGCVPSLNCYPPLEKLLNHLN
              760       770       780       790       800       810

         1040      1050      1060
pF1KSD SEKLIIDLPSREHESLCHILGDFQRE
       ::::::::::::::::::::::::::
XP_016 SEKLIIDLPSREHESLCHILGDFQRE
              820       830      

>>XP_011537719 (OMIM: 601810,615156,615807) PREDICTED: D  (700 aa)
 initn: 4604 init1: 4604 opt: 4604  Z-score: 5243.2  bits: 981.2 E(85289):    0
Smith-Waterman score: 4604; 100.0% identity (100.0% similar) in 700 aa overlap (361-1060:1-700)

              340       350       360       370       380       390
pF1KSD GLLLYLKTGQMYPVPANHLDKRELLKLRNQMAFSLFHRISKSATRQKTQLASLPQIIEEE
                                     ::::::::::::::::::::::::::::::
XP_011                               MAFSLFHRISKSATRQKTQLASLPQIIEEE
                                             10        20        30

              400       410       420       430       440       450
pF1KSD KTCKYCSQIGNCALYSRAVEQQMDCSSVPIVMLPKIEEETQHLKQTHLEYFSLWCLMLTL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KTCKYCSQIGNCALYSRAVEQQMDCSSVPIVMLPKIEEETQHLKQTHLEYFSLWCLMLTL
               40        50        60        70        80        90

              460       470       480       490       500       510
pF1KSD ESQSKDNKKNHQNIWLMPASEMEKSGSCIGNLIRMEHVKIVCDGQYLHNFQCKHGAIPVT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ESQSKDNKKNHQNIWLMPASEMEKSGSCIGNLIRMEHVKIVCDGQYLHNFQCKHGAIPVT
              100       110       120       130       140       150

              520       530       540       550       560       570
pF1KSD NLMAGDRVIVSGEERSLFALSRGYVKEINMTTVTCLLDRNLSVLPESTLFRLDQEEKNCD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NLMAGDRVIVSGEERSLFALSRGYVKEINMTTVTCLLDRNLSVLPESTLFRLDQEEKNCD
              160       170       180       190       200       210

              580       590       600       610       620       630
pF1KSD IDTPLGNLSKLMENTFVSKKLRDLIIDFREPQFISYLSSVLPHDAKDTVACILKGLNKPQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IDTPLGNLSKLMENTFVSKKLRDLIIDFREPQFISYLSSVLPHDAKDTVACILKGLNKPQ
              220       230       240       250       260       270

              640       650       660       670       680       690
pF1KSD RQAMKKVLLSKDYTLIVGMPGTGKTTTICTLVRILYACGFSVLLTSYTHSAVDNILLKLA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RQAMKKVLLSKDYTLIVGMPGTGKTTTICTLVRILYACGFSVLLTSYTHSAVDNILLKLA
              280       290       300       310       320       330

              700       710       720       730       740       750
pF1KSD KFKIGFLRLGQIQKVHPAIQQFTEQEICRSKSIKSLALLEELYNSQLIVATTCMGINHPI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KFKIGFLRLGQIQKVHPAIQQFTEQEICRSKSIKSLALLEELYNSQLIVATTCMGINHPI
              340       350       360       370       380       390

              760       770       780       790       800       810
pF1KSD FSRKIFDFCIVDEASQISQPICLGPLFFSRRFVLVGDHQQLPPLVLNREARALGMSESLF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FSRKIFDFCIVDEASQISQPICLGPLFFSRRFVLVGDHQQLPPLVLNREARALGMSESLF
              400       410       420       430       440       450

              820       830       840       850       860       870
pF1KSD KRLEQNKSAVVQLTVQYRMNSKIMSLSNKLTYEGKLECGSDKVANAVINLRHFKDVKLEL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KRLEQNKSAVVQLTVQYRMNSKIMSLSNKLTYEGKLECGSDKVANAVINLRHFKDVKLEL
              460       470       480       490       500       510

              880       890       900       910       920       930
pF1KSD EFYADYSDNPWLMGVFEPNNPVCFLNTDKVPAPEQVEKGGVSNVTEAKLIVFLTSIFVKA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EFYADYSDNPWLMGVFEPNNPVCFLNTDKVPAPEQVEKGGVSNVTEAKLIVFLTSIFVKA
              520       530       540       550       560       570

              940       950       960       970       980       990
pF1KSD GCSPSDIGIIAPYRQQLKIINDLLARSIGMVEVNTVDKYQGRDKSIVLVSFVRSNKDGTV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GCSPSDIGIIAPYRQQLKIINDLLARSIGMVEVNTVDKYQGRDKSIVLVSFVRSNKDGTV
              580       590       600       610       620       630

             1000      1010      1020      1030      1040      1050
pF1KSD GELLKDWRRLNVAITRAKHKLILLGCVPSLNCYPPLEKLLNHLNSEKLIIDLPSREHESL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GELLKDWRRLNVAITRAKHKLILLGCVPSLNCYPPLEKLLNHLNSEKLIIDLPSREHESL
              640       650       660       670       680       690

             1060
pF1KSD CHILGDFQRE
       ::::::::::
XP_011 CHILGDFQRE
              700

>>XP_005261980 (OMIM: 605794) PREDICTED: RNA helicase Mo  (1191 aa)
 initn: 269 init1:  90 opt: 380  Z-score: 427.6  bits: 91.0 E(85289): 4.5e-17
Smith-Waterman score: 409; 29.3% identity (57.6% similar) in 460 aa overlap (626-1043:725-1157)

         600       610       620       630       640           650 
pF1KSD IDFREPQFISYLSSVLPHDAKDTVACILKGLNKPQRQAMKKVLLSKDYT----LIVGMPG
                                     ::. :. :.:..: : :      .. : ::
XP_005 VLAPFTAEMSDWVDEIQTPKARKMEFFNPVLNENQKLAVKRIL-SGDCRPLPYILFGPPG
          700       710       720       730        740       750   

             660        670        680       690       700         
pF1KSD TGKTTTICTLV-RILYACGFS-VLLTSYTHSAVDNILLKLAKFKIGFLRLGQIQKVHPAI
       ::::.::   : .. .:   : .:. . ..::.: . :.: . :.  :. . . .:. : 
XP_005 TGKTVTIIEAVLQVHFALPDSRILVCAPSNSAADLVCLRLHESKV--LQPATMVRVN-AT
           760       770       780       790         800        810

     710       720       730         740         750        760    
pF1KSD QQFTEQEICRSKSIKSLALLEELYNSQL--IVATTCM--GINHPIFSR-KIFDFCIVDEA
        .: :  :   :     .  :......   :. :::   :. . :  :   :   .::::
XP_005 CRFEEIVIDAVKPYCRDG--EDIWKASRFRIIITTCSSSGLFYQIGVRVGHFTHVFVDEA
              820         830       840       850       860        

          770           780       790       800       810          
pF1KSD SQISQPICLGPLFF----SRRFVLVGDHQQLPPLVLNREARALGMSESLFKRL------E
       .: :.: :: :: .    : ..::.:: .:: :.. .: : : :.. :...::      .
XP_005 GQASEPECLIPLGLMSDISGQIVLAGDPMQLGPVIKSRLAMAYGLNVSFLERLMSRPAYQ
      870       880       890       900       910       920        

                     820       830       840        850       860  
pF1KSD QNKSA-----------VVQLTVQYRMNSKIMSLSNKLTYEGKLE-CGSDKVANAVINLRH
       ....:           :..:. .:: .  .. : ..: :. .:: :..  :...... ..
XP_005 RDENAFGACGAHNPLLVTKLVKNYRSHEALLMLPSRLFYHRELEVCADPTVVTSLLGWEK
      930       940       950       960       970       980        

            870       880       890       900       910       920  
pF1KSD FKDVKLELEFYADYSDNPWLMGVFEPNNPVCFLNTDKVPAPEQVEKGGVSNVTEAKLIVF
       .    . : :..  ...     . : ..:  :  .. :    :: .              
XP_005 LPKKGFPLIFHGVRGSE-----AREGKSPSWFNPAEAV----QVLR-----------YCC
      990      1000           1010      1020                       

            930       940       950       960         970       980
pF1KSD LTSIFVKAGCSPSDIGIIAPYRQQLKIINDLLARSIGM--VEVNTVDKYQGRDKSIVLVS
       : .  ...  : ::::.:.:::.:.. :  :: :.. .  ..:..:...::..  ....:
XP_005 LLAHSISSQVSASDIGVITPYRKQVEKIRILL-RNVDLMDIKVGSVEEFQGQEYLVIIIS
     1030      1040      1050      1060       1070      1080       

              990           1000      1010      1020      1030     
pF1KSD FVRSNKDGTVGE-----LLKDWRRLNVAITRAKHKLILLGCVPSLNCYPPLEKLLNH--L
        ::::.:    .     .:.. .:.:::::: :  ::.::    :   : .  ::..   
XP_005 TVRSNEDRFEDDRYFLGFLSNSKRFNVAITRPKALLIVLGNPHVLVRDPCFGALLEYSIT
      1090      1100      1110      1120      1130      1140       

          1040      1050      1060                 
pF1KSD NSEKLIIDLPSREHESLCHILGDFQRE                 
       :.  .  :::                                  
XP_005 NGVYMGCDLPPALQSLQNCGEGVADPSYPVVPESTGPEKHQEPS
      1150      1160      1170      1180      1190 

>>NP_061868 (OMIM: 605794) RNA helicase Mov10l1 isoform   (1211 aa)
 initn: 269 init1:  90 opt: 380  Z-score: 427.5  bits: 91.0 E(85289): 4.5e-17
Smith-Waterman score: 409; 29.3% identity (57.6% similar) in 460 aa overlap (626-1043:745-1177)

         600       610       620       630       640           650 
pF1KSD IDFREPQFISYLSSVLPHDAKDTVACILKGLNKPQRQAMKKVLLSKDYT----LIVGMPG
                                     ::. :. :.:..: : :      .. : ::
NP_061 VLAPFTAEMSDWVDEIQTPKARKMEFFNPVLNENQKLAVKRIL-SGDCRPLPYILFGPPG
          720       730       740       750        760       770   

             660        670        680       690       700         
pF1KSD TGKTTTICTLV-RILYACGFS-VLLTSYTHSAVDNILLKLAKFKIGFLRLGQIQKVHPAI
       ::::.::   : .. .:   : .:. . ..::.: . :.: . :.  :. . . .:. : 
NP_061 TGKTVTIIEAVLQVHFALPDSRILVCAPSNSAADLVCLRLHESKV--LQPATMVRVN-AT
           780       790       800       810         820        830

     710       720       730         740         750        760    
pF1KSD QQFTEQEICRSKSIKSLALLEELYNSQL--IVATTCM--GINHPIFSR-KIFDFCIVDEA
        .: :  :   :     .  :......   :. :::   :. . :  :   :   .::::
NP_061 CRFEEIVIDAVKPYCRDG--EDIWKASRFRIIITTCSSSGLFYQIGVRVGHFTHVFVDEA
              840         850       860       870       880        

          770           780       790       800       810          
pF1KSD SQISQPICLGPLFF----SRRFVLVGDHQQLPPLVLNREARALGMSESLFKRL------E
       .: :.: :: :: .    : ..::.:: .:: :.. .: : : :.. :...::      .
NP_061 GQASEPECLIPLGLMSDISGQIVLAGDPMQLGPVIKSRLAMAYGLNVSFLERLMSRPAYQ
      890       900       910       920       930       940        

                     820       830       840        850       860  
pF1KSD QNKSA-----------VVQLTVQYRMNSKIMSLSNKLTYEGKLE-CGSDKVANAVINLRH
       ....:           :..:. .:: .  .. : ..: :. .:: :..  :...... ..
NP_061 RDENAFGACGAHNPLLVTKLVKNYRSHEALLMLPSRLFYHRELEVCADPTVVTSLLGWEK
      950       960       970       980       990      1000        

            870       880       890       900       910       920  
pF1KSD FKDVKLELEFYADYSDNPWLMGVFEPNNPVCFLNTDKVPAPEQVEKGGVSNVTEAKLIVF
       .    . : :..  ...     . : ..:  :  .. :    :: .              
NP_061 LPKKGFPLIFHGVRGSE-----AREGKSPSWFNPAEAV----QVLR-----------YCC
     1010      1020           1030      1040                       

            930       940       950       960         970       980
pF1KSD LTSIFVKAGCSPSDIGIIAPYRQQLKIINDLLARSIGM--VEVNTVDKYQGRDKSIVLVS
       : .  ...  : ::::.:.:::.:.. :  :: :.. .  ..:..:...::..  ....:
NP_061 LLAHSISSQVSASDIGVITPYRKQVEKIRILL-RNVDLMDIKVGSVEEFQGQEYLVIIIS
     1050      1060      1070      1080       1090      1100       

              990           1000      1010      1020      1030     
pF1KSD FVRSNKDGTVGE-----LLKDWRRLNVAITRAKHKLILLGCVPSLNCYPPLEKLLNH--L
        ::::.:    .     .:.. .:.:::::: :  ::.::    :   : .  ::..   
NP_061 TVRSNEDRFEDDRYFLGFLSNSKRFNVAITRPKALLIVLGNPHVLVRDPCFGALLEYSIT
      1110      1120      1130      1140      1150      1160       

          1040      1050      1060                 
pF1KSD NSEKLIIDLPSREHESLCHILGDFQRE                 
       :.  .  :::                                  
NP_061 NGVYMGCDLPPALQSLQNCGEGVADPSYPVVPESTGPEKHQEPS
      1170      1180      1190      1200      1210 

>>NP_001157577 (OMIM: 605794) RNA helicase Mov10l1 isofo  (1165 aa)
 initn: 269 init1:  90 opt: 372  Z-score: 418.6  bits: 89.3 E(85289): 1.4e-16
Smith-Waterman score: 401; 29.5% identity (58.6% similar) in 430 aa overlap (626-1015:725-1127)

         600       610       620       630       640           650 
pF1KSD IDFREPQFISYLSSVLPHDAKDTVACILKGLNKPQRQAMKKVLLSKDYT----LIVGMPG
                                     ::. :. :.:..: : :      .. : ::
NP_001 VLAPFTAEMSDWVDEIQTPKARKMEFFNPVLNENQKLAVKRIL-SGDCRPLPYILFGPPG
          700       710       720       730        740       750   

             660        670        680       690       700         
pF1KSD TGKTTTICTLV-RILYACGFS-VLLTSYTHSAVDNILLKLAKFKIGFLRLGQIQKVHPAI
       ::::.::   : .. .:   : .:. . ..::.: . :.: . :.  :. . . .:. : 
NP_001 TGKTVTIIEAVLQVHFALPDSRILVCAPSNSAADLVCLRLHESKV--LQPATMVRVN-AT
           760       770       780       790         800        810

     710       720       730         740         750        760    
pF1KSD QQFTEQEICRSKSIKSLALLEELYNSQL--IVATTCM--GINHPIFSR-KIFDFCIVDEA
        .: :  :   :     .  :......   :. :::   :. . :  :   :   .::::
NP_001 CRFEEIVIDAVKPYCRDG--EDIWKASRFRIIITTCSSSGLFYQIGVRVGHFTHVFVDEA
              820         830       840       850       860        

          770           780       790       800       810          
pF1KSD SQISQPICLGPLFF----SRRFVLVGDHQQLPPLVLNREARALGMSESLFKRL------E
       .: :.: :: :: .    : ..::.:: .:: :.. .: : : :.. :...::      .
NP_001 GQASEPECLIPLGLMSDISGQIVLAGDPMQLGPVIKSRLAMAYGLNVSFLERLMSRPAYQ
      870       880       890       900       910       920        

                     820       830       840        850       860  
pF1KSD QNKSA-----------VVQLTVQYRMNSKIMSLSNKLTYEGKLE-CGSDKVANAVINLRH
       ....:           :..:. .:: .  .. : ..: :. .:: :..  :...... ..
NP_001 RDENAFGACGAHNPLLVTKLVKNYRSHEALLMLPSRLFYHRELEVCADPTVVTSLLGWEK
      930       940       950       960       970       980        

            870       880       890       900       910       920  
pF1KSD FKDVKLELEFYADYSDNPWLMGVFEPNNPVCFLNTDKVPAPEQVEKGGVSNVTEAKLIVF
       .    . : :..  ...     . : ..:  :  .. :    :: .              
NP_001 LPKKGFPLIFHGVRGSE-----AREGKSPSWFNPAEAV----QVLR-----------YCC
      990      1000           1010      1020                       

            930       940       950       960         970       980
pF1KSD LTSIFVKAGCSPSDIGIIAPYRQQLKIINDLLARSIGM--VEVNTVDKYQGRDKSIVLVS
       : .  ...  : ::::.:.:::.:.. :  :: :.. .  ..:..:...::..  ....:
NP_001 LLAHSISSQVSASDIGVITPYRKQVEKIRILL-RNVDLMDIKVGSVEEFQGQEYLVIIIS
     1030      1040      1050      1060       1070      1080       

              990           1000      1010      1020      1030     
pF1KSD FVRSNKDGTVGE-----LLKDWRRLNVAITRAKHKLILLGCVPSLNCYPPLEKLLNHLNS
        ::::.:    .     .:.. .:.:::::: :  ::.::                    
NP_001 TVRSNEDRFEDDRYFLGFLSNSKRFNVAITRPKALLIVLGNPHVLVRLWRGGGRPLLPSG
      1090      1100      1110      1120      1130      1140       

        1040      1050      1060
pF1KSD EKLIIDLPSREHESLCHILGDFQRE
                                
NP_001 ARIHRTREASGAQLICSG       
      1150      1160            

>>NP_001157578 (OMIM: 605794) RNA helicase Mov10l1 isofo  (338 aa)
 initn: 296 init1:  90 opt: 310  Z-score: 356.1  bits: 75.9 E(85289): 4.3e-13
Smith-Waterman score: 324; 29.2% identity (58.3% similar) in 319 aa overlap (756-1043:7-304)

         730       740       750       760       770           780 
pF1KSD LALLEELYNSQLIVATTCMGINHPIFSRKIFDFCIVDEASQISQPICLGPLFF----SRR
                                     :   .::::.: :.: :: :: .    : .
NP_001                         MFRVGHFTHVFVDEAGQASEPECLIPLGLMSDISGQ
                                       10        20        30      

             790       800       810                        820    
pF1KSD FVLVGDHQQLPPLVLNREARALGMSESLFKRL------EQNKSA-----------VVQLT
       .::.:: .:: :.. .: : : :.. :...::      .....:           :..:.
NP_001 IVLAGDPMQLGPVIKSRLAMAYGLNVSFLERLMSRPAYQRDENAFGACGAHNPLLVTKLV
         40        50        60        70        80        90      

          830       840        850       860       870       880   
pF1KSD VQYRMNSKIMSLSNKLTYEGKLE-CGSDKVANAVINLRHFKDVKLELEFYADYSDNPWLM
        .:: .  .. : ..: :. .:: :..  :...... ...    . : :..  ...    
NP_001 KNYRSHEALLMLPSRLFYHRELEVCADPTVVTSLLGWEKLPKKGFPLIFHGVRGSE----
        100       110       120       130       140       150      

           890       900       910       920       930       940   
pF1KSD GVFEPNNPVCFLNTDKVPAPEQVEKGGVSNVTEAKLIVFLTSIFVKAGCSPSDIGIIAPY
        . : ..:  :  .. :    :: .              : .  ...  : ::::.:.::
NP_001 -AREGKSPSWFNPAEAV----QVLR-----------YCCLLAHSISSQVSASDIGVITPY
             160           170                  180       190      

           950       960         970       980       990           
pF1KSD RQQLKIINDLLARSIGM--VEVNTVDKYQGRDKSIVLVSFVRSNKDGTVGE-----LLKD
       :.:.. :  :: :.. .  ..:..:...::..  ....: ::::.:    .     .:..
NP_001 RKQVEKIRILL-RNVDLMDIKVGSVEEFQGQEYLVIIISTVRSNEDRFEDDRYFLGFLSN
        200        210       220       230       240       250     

       1000      1010      1020      1030        1040      1050    
pF1KSD WRRLNVAITRAKHKLILLGCVPSLNCYPPLEKLLNH--LNSEKLIIDLPSREHESLCHIL
        .:.:::::: :  ::.::    :   : .  ::..   :.  .  :::           
NP_001 SKRFNVAITRPKALLIVLGNPHVLVRDPCFGALLEYSITNGVYMGCDLPPALQSLQNCGE
         260       270       280       290       300       310     

         1060                 
pF1KSD GDFQRE                 
                              
NP_001 GVADPSYPVVPESTGPEKHQEPS
         320       330        

>>NP_002902 (OMIM: 601430) regulator of nonsense transcr  (1118 aa)
 initn: 505 init1: 182 opt: 299  Z-score: 335.7  bits: 73.9 E(85289): 5.8e-12
Smith-Waterman score: 616; 29.9% identity (59.5% similar) in 538 aa overlap (556-1050:416-910)

         530       540       550       560        570       580    
pF1KSD SLFALSRGYVKEINMTTVTCLLDRNLSVLPESTLF-RLDQEEKNCDIDTPLGNLSKLMEN
                                     .:: : :...  :.  .:    ..:  . .
NP_002 NYGDEIAIELRSSVGAPVEVTHNFQVDFVWKSTSFDRMQSALKTFAVDET--SVSGYIYH
         390       400       410       420       430         440   

          590       600       610       620       630       640    
pF1KSD TFVSKKLRDLIIDFREPQFISYLSSVLPHDAKDTVACILKGLNKPQRQAMKKVLLSKDYT
        .......:.::  . :.   . .. ::             ::. :  :.: :: ..  .
NP_002 KLLGHEVEDVIIKCQLPK--RFTAQGLPD------------LNHSQVYAVKTVL-QRPLS
           450       460         470                   480         

          650       660       670        680                  690  
pF1KSD LIVGMPGTGKTTTICTLVRILYACGFS-VLLTSYTHSAVDNILLKL-----------AKF
       :: : ::::::.:  :.:  :   : . ::. . .. :::..  :.           :: 
NP_002 LIQGPPGTGKTVTSATIVYHLARQGNGPVLVCAPSNIAVDQLTEKIHQTGLKVVRLCAKS
      490       500       510       520       530       540        

                   700         710                 720       730   
pF1KSD K------IGFLRL-GQIQKVH--PAIQQFTEQ-----EIC-----RSKSIKSLALLEELY
       .      ..:: : .::...   : .:.. .      :.      : ...:  :  : :.
NP_002 REAIDSPVSFLALHNQIRNMDSMPELQKLQQLKDETGELSSADEKRYRALKRTAERELLM
      550       560       570       580       590       600        

           740       750       760       770        780       790  
pF1KSD NSQLIVATTCMGINHPIFSRKIFDFCIVDEASQISQPICLGPLFF-SRRFVLVGDHQQLP
       :.. ..  ::.: . : ...  :   ..::..: ..: :. :. . .....::::: :: 
NP_002 NAD-VICCTCVGAGDPRLAKMQFRSILIDESTQATEPECMVPVVLGAKQLILVGDHCQLG
      610        620       630       640       650       660       

            800       810       820       830       840       850  
pF1KSD PLVLNREARALGMSESLFKRLEQNKSAVVQLTVQYRMNSKIMSLSNKLTYEGKLECGSDK
       :.:. ..:   :.:.:::.::       ..: :::::.  . .. ... :::.:. :   
NP_002 PVVMCKKAAKAGLSQSLFERLVVLGIRPIRLQVQYRMHPALSAFPSNIFYEGSLQNG---
       670       680       690       700       710       720       

            860       870       880       890       900       910  
pF1KSD VANAVINLRHFKDVKLELEFYADYSDNPWLMGVFEPNNPVCFLNTDKVPAPEQVEKGGVS
       :. :         ::  ..:        :     .:..:. :  :.   . :.. ..:.:
NP_002 VTAA-------DRVKKGFDF-------QWP----QPDKPMFFYVTQ---GQEEIASSGTS
                 730              740           750          760   

              920       930       940              950       960   
pF1KSD --NVTEAKLIVFLTSIFVKAGCSPSDIGIIAPYR-------QQLKIINDLLARSIGMVEV
         : :::  .  .:. ..::: .:..::::.::.       : ... ..: ..    ::.
NP_002 YLNRTEAANVEKITTKLLKAGAKPDQIGIITPYEGQRSYLVQYMQFSGSLHTKLYQEVEI
           770       780       790       800       810       820   

           970       980       990      1000      1010      1020   
pF1KSD NTVDKYQGRDKSIVLVSFVRSNKDGTVGELLKDWRRLNVAITRAKHKLILLGCVPSLNCY
        .:: .:::.:.....: ::.:.   .: .:.: ::::::.:::.. .:..:   .:.  
NP_002 ASVDAFQGREKDFIILSCVRANEHQGIG-FLNDPRRLNVALTRARYGVIIVGNPKALSKQ
           830       840       850        860       870       880  

          1030      1040       1050      1060                      
pF1KSD PPLEKLLNHLNSEKLIIDLP-SREHESLCHILGDFQRE                      
       :  ..:::. . .:.... : .  .:::                                
NP_002 PLWNHLLNYYKEQKVLVEGPLNNLRESLMQFSKPRKLVNTINPGARFMTTAMYDAREAII
            890       900       910       920       930       940  

>>XP_016882595 (OMIM: 601430) PREDICTED: regulator of no  (1126 aa)
 initn: 505 init1: 182 opt: 299  Z-score: 335.7  bits: 73.9 E(85289): 5.9e-12
Smith-Waterman score: 616; 29.9% identity (59.5% similar) in 538 aa overlap (556-1050:424-918)

         530       540       550       560        570       580    
pF1KSD SLFALSRGYVKEINMTTVTCLLDRNLSVLPESTLF-RLDQEEKNCDIDTPLGNLSKLMEN
                                     .:: : :...  :.  .:    ..:  . .
XP_016 DYGDEIAIELRSSVGAPVEVTHNFQVDFVWKSTSFDRMQSALKTFAVDET--SVSGYIYH
           400       410       420       430       440         450 

          590       600       610       620       630       640    
pF1KSD TFVSKKLRDLIIDFREPQFISYLSSVLPHDAKDTVACILKGLNKPQRQAMKKVLLSKDYT
        .......:.::  . :.   . .. ::             ::. :  :.: :: ..  .
XP_016 KLLGHEVEDVIIKCQLPK--RFTAQGLPD------------LNHSQVYAVKTVL-QRPLS
             460         470                   480       490       

          650       660       670        680                  690  
pF1KSD LIVGMPGTGKTTTICTLVRILYACGFS-VLLTSYTHSAVDNILLKL-----------AKF
       :: : ::::::.:  :.:  :   : . ::. . .. :::..  :.           :: 
XP_016 LIQGPPGTGKTVTSATIVYHLARQGNGPVLVCAPSNIAVDQLTEKIHQTGLKVVRLCAKS
        500       510       520       530       540       550      

                   700         710                 720       730   
pF1KSD K------IGFLRL-GQIQKVH--PAIQQFTEQ-----EIC-----RSKSIKSLALLEELY
       .      ..:: : .::...   : .:.. .      :.      : ...:  :  : :.
XP_016 REAIDSPVSFLALHNQIRNMDSMPELQKLQQLKDETGELSSADEKRYRALKRTAERELLM
        560       570       580       590       600       610      

           740       750       760       770        780       790  
pF1KSD NSQLIVATTCMGINHPIFSRKIFDFCIVDEASQISQPICLGPLFF-SRRFVLVGDHQQLP
       :.. ..  ::.: . : ...  :   ..::..: ..: :. :. . .....::::: :: 
XP_016 NAD-VICCTCVGAGDPRLAKMQFRSILIDESTQATEPECMVPVVLGAKQLILVGDHCQLG
         620       630       640       650       660       670     

            800       810       820       830       840       850  
pF1KSD PLVLNREARALGMSESLFKRLEQNKSAVVQLTVQYRMNSKIMSLSNKLTYEGKLECGSDK
       :.:. ..:   :.:.:::.::       ..: :::::.  . .. ... :::.:. :   
XP_016 PVVMCKKAAKAGLSQSLFERLVVLGIRPIRLQVQYRMHPALSAFPSNIFYEGSLQNG---
         680       690       700       710       720       730     

            860       870       880       890       900       910  
pF1KSD VANAVINLRHFKDVKLELEFYADYSDNPWLMGVFEPNNPVCFLNTDKVPAPEQVEKGGVS
       :. :         ::  ..:        :     .:..:. :  :.   . :.. ..:.:
XP_016 VTAA-------DRVKKGFDF-------QWP----QPDKPMFFYVTQ---GQEEIASSGTS
                   740                  750       760          770 

              920       930       940              950       960   
pF1KSD --NVTEAKLIVFLTSIFVKAGCSPSDIGIIAPYR-------QQLKIINDLLARSIGMVEV
         : :::  .  .:. ..::: .:..::::.::.       : ... ..: ..    ::.
XP_016 YLNRTEAANVEKITTKLLKAGAKPDQIGIITPYEGQRSYLVQYMQFSGSLHTKLYQEVEI
             780       790       800       810       820       830 

           970       980       990      1000      1010      1020   
pF1KSD NTVDKYQGRDKSIVLVSFVRSNKDGTVGELLKDWRRLNVAITRAKHKLILLGCVPSLNCY
        .:: .:::.:.....: ::.:.   .: .:.: ::::::.:::.. .:..:   .:.  
XP_016 ASVDAFQGREKDFIILSCVRANEHQGIG-FLNDPRRLNVALTRARYGVIIVGNPKALSKQ
             840       850        860       870       880       890

          1030      1040       1050      1060                      
pF1KSD PPLEKLLNHLNSEKLIIDLP-SREHESLCHILGDFQRE                      
       :  ..:::. . .:.... : .  .:::                                
XP_016 PLWNHLLNYYKEQKVLVEGPLNNLRESLMQFSKPRKLVNTINPGARFMTTAMYDAREAII
              900       910       920       930       940       950




1060 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Wed Nov  2 23:51:33 2016 done: Wed Nov  2 23:51:35 2016
 Total Scan time: 14.170 Total Display time:  0.290

Function used was FASTA [36.3.4 Apr, 2011]
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