Result of FASTA (omim) for pF1KSDA0057
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KSDA0057, 370 aa
  1>>>pF1KSDA0057 370 - 370 aa - 370 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 4.9431+/-0.000463; mu= 18.4045+/- 0.028
 mean_var=67.5170+/-13.680, 0's: 0 Z-trim(109.3): 36  B-trim: 0 in 0/51
 Lambda= 0.156087
 statistics sampled from 17452 (17488) to 17452 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.566), E-opt: 0.2 (0.205), width:  16
 Scan time:  6.580

The best scores are:                                      opt bits E(85289)
NP_036420 (OMIM: 608485) translocating chain-assoc ( 370) 2499 572.2 6.6e-163
XP_011513307 (OMIM: 608485) PREDICTED: translocati ( 333) 2095 481.2 1.5e-135
NP_055109 (OMIM: 605190) translocating chain-assoc ( 374) 1342 311.7 1.8e-84
NP_001304733 (OMIM: 605190) translocating chain-as ( 343) 1234 287.3 3.5e-77
NP_001304734 (OMIM: 605190) translocating chain-as ( 288) 1067 249.6 6.4e-66
XP_016868756 (OMIM: 605190) PREDICTED: translocati ( 278)  988 231.8 1.4e-60
XP_016868755 (OMIM: 605190) PREDICTED: translocati ( 278)  988 231.8 1.4e-60
NP_859530 (OMIM: 606920) ceramide synthase 2 [Homo ( 380)  211 57.0 8.4e-08
XP_011507754 (OMIM: 606920) PREDICTED: ceramide sy ( 380)  211 57.0 8.4e-08
NP_071358 (OMIM: 606920) ceramide synthase 2 [Homo ( 380)  211 57.0 8.4e-08
XP_011507753 (OMIM: 606920) PREDICTED: ceramide sy ( 400)  211 57.0 8.8e-08
XP_011526595 (OMIM: 615334) PREDICTED: ceramide sy ( 394)  208 56.3 1.4e-07
XP_016882793 (OMIM: 615334) PREDICTED: ceramide sy ( 394)  208 56.3 1.4e-07
XP_011526593 (OMIM: 615334) PREDICTED: ceramide sy ( 394)  208 56.3 1.4e-07
XP_011526592 (OMIM: 615334) PREDICTED: ceramide sy ( 394)  208 56.3 1.4e-07
XP_011526594 (OMIM: 615334) PREDICTED: ceramide sy ( 394)  208 56.3 1.4e-07
XP_011526596 (OMIM: 615334) PREDICTED: ceramide sy ( 394)  208 56.3 1.4e-07
XP_016882792 (OMIM: 615334) PREDICTED: ceramide sy ( 394)  208 56.3 1.4e-07
NP_078828 (OMIM: 615334) ceramide synthase 4 [Homo ( 394)  208 56.3 1.4e-07
XP_011526597 (OMIM: 615334) PREDICTED: ceramide sy ( 394)  208 56.3 1.4e-07
XP_016882794 (OMIM: 615334) PREDICTED: ceramide sy ( 394)  208 56.3 1.4e-07
NP_001317998 (OMIM: 615335) ceramide synthase 5 is ( 323)  180 49.9 9.4e-06
XP_016875691 (OMIM: 615335) PREDICTED: ceramide sy ( 334)  180 50.0 9.7e-06
NP_001268660 (OMIM: 615335) ceramide synthase 5 is ( 334)  180 50.0 9.7e-06
NP_001318000 (OMIM: 615335) ceramide synthase 5 is ( 381)  180 50.0 1.1e-05
NP_982288 (OMIM: 615336) ceramide synthase 6 isofo ( 384)  180 50.0 1.1e-05
NP_001317999 (OMIM: 615335) ceramide synthase 5 is ( 392)  180 50.0 1.1e-05
NP_001243055 (OMIM: 615336) ceramide synthase 6 is ( 392)  180 50.0 1.1e-05
NP_671723 (OMIM: 615335) ceramide synthase 5 isofo ( 392)  180 50.0 1.1e-05
XP_005269277 (OMIM: 615335) PREDICTED: ceramide sy ( 409)  180 50.0 1.1e-05
XP_016875693 (OMIM: 615335) PREDICTED: ceramide sy ( 290)  175 48.8 1.9e-05
XP_016859238 (OMIM: 615336) PREDICTED: ceramide sy ( 251)  174 48.5   2e-05
XP_016875694 (OMIM: 615335) PREDICTED: ceramide sy ( 237)  172 48.0 2.6e-05
NP_001318002 (OMIM: 615335) ceramide synthase 5 is ( 237)  172 48.0 2.6e-05
NP_001318001 (OMIM: 615335) ceramide synthase 5 is ( 248)  172 48.1 2.7e-05


>>NP_036420 (OMIM: 608485) translocating chain-associate  (370 aa)
 initn: 2499 init1: 2499 opt: 2499  Z-score: 3045.7  bits: 572.2 E(85289): 6.6e-163
Smith-Waterman score: 2499; 100.0% identity (100.0% similar) in 370 aa overlap (1-370:1-370)

               10        20        30        40        50        60
pF1KSD MAFRRRTKSYPLFSQEFVIHNHADIGFCLVLCVLIGLMFEVTAKTAFLFILPQYNISVPT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 MAFRRRTKSYPLFSQEFVIHNHADIGFCLVLCVLIGLMFEVTAKTAFLFILPQYNISVPT
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KSD ADSETVHYHYGPKDLVTILFYIFITIILHAVVQEYILDKISKRLHLSKVKHSKFNESGQL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 ADSETVHYHYGPKDLVTILFYIFITIILHAVVQEYILDKISKRLHLSKVKHSKFNESGQL
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KSD VVFHFTSVIWCFYVVVTEGYLTNPRSLWEDYPHVHLPFQVKFFYLCQLAYWLHALPELYF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 VVFHFTSVIWCFYVVVTEGYLTNPRSLWEDYPHVHLPFQVKFFYLCQLAYWLHALPELYF
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KSD QKVRKEEIPRQLQYICLYLVHIAGAYLLNLSRLGLILLLLQYSTEFLFHTARLFYFADEN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 QKVRKEEIPRQLQYICLYLVHIAGAYLLNLSRLGLILLLLQYSTEFLFHTARLFYFADEN
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KSD NEKLFSAWAAVFGVTRLFILTLAVLAIGFGLARMENQAFDPEKGNFNTLFCRLCVLLLVC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 NEKLFSAWAAVFGVTRLFILTLAVLAIGFGLARMENQAFDPEKGNFNTLFCRLCVLLLVC
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KSD AAQAWLMWRFIHSQLRHWREYWNEQSAKRRVPATPRLPARLIKRESGYHENGVVKAENGT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 AAQAWLMWRFIHSQLRHWREYWNEQSAKRRVPATPRLPARLIKRESGYHENGVVKAENGT
              310       320       330       340       350       360

              370
pF1KSD SPRTKKLKSP
       ::::::::::
NP_036 SPRTKKLKSP
              370

>>XP_011513307 (OMIM: 608485) PREDICTED: translocating c  (333 aa)
 initn: 2095 init1: 2095 opt: 2095  Z-score: 2554.6  bits: 481.2 E(85289): 1.5e-135
Smith-Waterman score: 2095; 100.0% identity (100.0% similar) in 309 aa overlap (62-370:25-333)

              40        50        60        70        80        90 
pF1KSD CVLIGLMFEVTAKTAFLFILPQYNISVPTADSETVHYHYGPKDLVTILFYIFITIILHAV
                                     ::::::::::::::::::::::::::::::
XP_011       MYKYFIEIWPSITPTLRSGITEICDSETVHYHYGPKDLVTILFYIFITIILHAV
                     10        20        30        40        50    

             100       110       120       130       140       150 
pF1KSD VQEYILDKISKRLHLSKVKHSKFNESGQLVVFHFTSVIWCFYVVVTEGYLTNPRSLWEDY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VQEYILDKISKRLHLSKVKHSKFNESGQLVVFHFTSVIWCFYVVVTEGYLTNPRSLWEDY
           60        70        80        90       100       110    

             160       170       180       190       200       210 
pF1KSD PHVHLPFQVKFFYLCQLAYWLHALPELYFQKVRKEEIPRQLQYICLYLVHIAGAYLLNLS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PHVHLPFQVKFFYLCQLAYWLHALPELYFQKVRKEEIPRQLQYICLYLVHIAGAYLLNLS
          120       130       140       150       160       170    

             220       230       240       250       260       270 
pF1KSD RLGLILLLLQYSTEFLFHTARLFYFADENNEKLFSAWAAVFGVTRLFILTLAVLAIGFGL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RLGLILLLLQYSTEFLFHTARLFYFADENNEKLFSAWAAVFGVTRLFILTLAVLAIGFGL
          180       190       200       210       220       230    

             280       290       300       310       320       330 
pF1KSD ARMENQAFDPEKGNFNTLFCRLCVLLLVCAAQAWLMWRFIHSQLRHWREYWNEQSAKRRV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ARMENQAFDPEKGNFNTLFCRLCVLLLVCAAQAWLMWRFIHSQLRHWREYWNEQSAKRRV
          240       250       260       270       280       290    

             340       350       360       370
pF1KSD PATPRLPARLIKRESGYHENGVVKAENGTSPRTKKLKSP
       :::::::::::::::::::::::::::::::::::::::
XP_011 PATPRLPARLIKRESGYHENGVVKAENGTSPRTKKLKSP
          300       310       320       330   

>>NP_055109 (OMIM: 605190) translocating chain-associate  (374 aa)
 initn: 1316 init1: 1081 opt: 1342  Z-score: 1637.5  bits: 311.7 E(85289): 1.8e-84
Smith-Waterman score: 1342; 52.5% identity (81.6% similar) in 375 aa overlap (1-369:1-373)

                10        20        30        40        50         
pF1KSD MAFRRR-TKSYPLFSQEFVIHNHADIGFCLVLCVLIGLMFEVTAKTAFLFILPQYNISVP
       ::.:.. ::: :..:.:::..:::::  :...  :.:::::.:::....:.  :::...:
NP_055 MAIRKKSTKSPPVLSHEFVLQNHADIVSCVAMVFLLGLMFEITAKASIIFVTLQYNVTLP
               10        20        30        40        50        60

      60            70        80        90       100       110     
pF1KSD TAD---SETVH-YHYGPKDLVTILFYIFITIILHAVVQEYILDKISKRLHLSKVKHSKFN
       ...   .:.:  :.:: :::.:..::....::.:::.:::.::::..:.:.::.::::::
NP_055 ATEEQATESVSLYYYGIKDLATVFFYMLVAIIIHAVIQEYMLDKINRRMHFSKTKHSKFN
               70        80        90       100       110       120

         120       130       140       150       160       170     
pF1KSD ESGQLVVFHFTSVIWCFYVVVTEGYLTNPRSLWEDYPHVHLPFQVKFFYLCQLAYWLHAL
       ::::: .:.. . .:  .....:.:...:  ::. :::  . ::.::::. ::::::::.
NP_055 ESGQLSAFYLFACVWGTFILISENYISDPTILWRAYPHNLMTFQMKFFYISQLAYWLHAF
              130       140       150       160       170       180

         180       190       200       210       220       230     
pF1KSD PELYFQKVRKEEIPRQLQYICLYLVHIAGAYLLNLSRLGLILLLLQYSTEFLFHTARLFY
       :::::::..::.::::: :: ::: ::::::::::..:::.::.:.: .::::: .::::
NP_055 PELYFQKTKKEDIPRQLVYIGLYLFHIAGAYLLNLNHLGLVLLVLHYFVEFLFHISRLFY
              190       200       210       220       230       240

         240       250       260       270       280       290     
pF1KSD FADENNEKLFSAWAAVFGVTRLFILTLAVLAIGFGLARMENQAFDPEKGNFNTLFCRLCV
       :..:. .: :: ::..: . ::. : :.::..:::::: ::: .:   ::::.:  :. :
NP_055 FSNEKYQKGFSLWAVLFVLGRLLTLILSVLTVGFGLARAENQKLDFSTGNFNVLAVRIAV
              250       260       270       280       290       300

         300       310       320        330       340       350    
pF1KSD LLLVCAAQAWLMWRFIHSQLRHWREYWNEQS-AKRRVPATPRLPARLIKRESGYHENGVV
       :  .:..::..::.::. :::.:::.   :. : .. :.. .  .:  :. .    ::..
NP_055 LASICVTQAFMMWKFINFQLRRWREHSAFQAPAVKKKPTVTK--GRSSKKGTENGVNGTL
              310       320       330       340         350        

          360       370
pF1KSD KAENGTSPRTKKLKSP
        .. . :::.:: :: 
NP_055 TSNVADSPRNKKEKSS
      360       370    

>>NP_001304733 (OMIM: 605190) translocating chain-associ  (343 aa)
 initn: 1213 init1: 1081 opt: 1234  Z-score: 1506.6  bits: 287.3 E(85289): 3.5e-77
Smith-Waterman score: 1234; 52.3% identity (81.1% similar) in 344 aa overlap (31-369:1-342)

               10        20        30        40        50        60
pF1KSD MAFRRRTKSYPLFSQEFVIHNHADIGFCLVLCVLIGLMFEVTAKTAFLFILPQYNISVPT
                                     .  :.:::::.:::....:.  :::...:.
NP_001                               MVFLLGLMFEITAKASIIFVTLQYNVTLPA
                                             10        20        30

                   70        80        90       100       110      
pF1KSD AD---SETVH-YHYGPKDLVTILFYIFITIILHAVVQEYILDKISKRLHLSKVKHSKFNE
       ..   .:.:  :.:: :::.:..::....::.:::.:::.::::..:.:.::.:::::::
NP_001 TEEQATESVSLYYYGIKDLATVFFYMLVAIIIHAVIQEYMLDKINRRMHFSKTKHSKFNE
               40        50        60        70        80        90

        120       130       140       150       160       170      
pF1KSD SGQLVVFHFTSVIWCFYVVVTEGYLTNPRSLWEDYPHVHLPFQVKFFYLCQLAYWLHALP
       :::: .:.. . .:  .....:.:...:  ::. :::  . ::.::::. ::::::::.:
NP_001 SGQLSAFYLFACVWGTFILISENYISDPTILWRAYPHNLMTFQMKFFYISQLAYWLHAFP
              100       110       120       130       140       150

        180       190       200       210       220       230      
pF1KSD ELYFQKVRKEEIPRQLQYICLYLVHIAGAYLLNLSRLGLILLLLQYSTEFLFHTARLFYF
       ::::::..::.::::: :: ::: ::::::::::..:::.::.:.: .::::: .:::::
NP_001 ELYFQKTKKEDIPRQLVYIGLYLFHIAGAYLLNLNHLGLVLLVLHYFVEFLFHISRLFYF
              160       170       180       190       200       210

        240       250       260       270       280       290      
pF1KSD ADENNEKLFSAWAAVFGVTRLFILTLAVLAIGFGLARMENQAFDPEKGNFNTLFCRLCVL
       ..:. .: :: ::..: . ::. : :.::..:::::: ::: .:   ::::.:  :. ::
NP_001 SNEKYQKGFSLWAVLFVLGRLLTLILSVLTVGFGLARAENQKLDFSTGNFNVLAVRIAVL
              220       230       240       250       260       270

        300       310       320        330       340       350     
pF1KSD LLVCAAQAWLMWRFIHSQLRHWREYWNEQS-AKRRVPATPRLPARLIKRESGYHENGVVK
         .:..::..::.::. :::.:::.   :. : .. :.. .  .:  :. .    ::.. 
NP_001 ASICVTQAFMMWKFINFQLRRWREHSAFQAPAVKKKPTVTK--GRSSKKGTENGVNGTLT
              280       290       300       310         320        

         360       370
pF1KSD AENGTSPRTKKLKSP
       .. . :::.:: :: 
NP_001 SNVADSPRNKKEKSS
      330       340   

>>NP_001304734 (OMIM: 605190) translocating chain-associ  (288 aa)
 initn: 1056 init1: 1016 opt: 1067  Z-score: 1304.4  bits: 249.6 E(85289): 6.4e-66
Smith-Waterman score: 1067; 53.6% identity (81.0% similar) in 289 aa overlap (82-369:1-287)

              60        70        80        90       100       110 
pF1KSD PQYNISVPTADSETVHYHYGPKDLVTILFYIFITIILHAVVQEYILDKISKRLHLSKVKH
                                     ....::.:::.:::.::::..:.:.::.::
NP_001                               MLVAIIIHAVIQEYMLDKINRRMHFSKTKH
                                             10        20        30

             120       130       140       150       160       170 
pF1KSD SKFNESGQLVVFHFTSVIWCFYVVVTEGYLTNPRSLWEDYPHVHLPFQVKFFYLCQLAYW
       ::::::::: .:.. . .:  .....:.:...:  ::. :::  . ::.::::. :::::
NP_001 SKFNESGQLSAFYLFACVWGTFILISENYISDPTILWRAYPHNLMTFQMKFFYISQLAYW
               40        50        60        70        80        90

             180       190       200       210       220       230 
pF1KSD LHALPELYFQKVRKEEIPRQLQYICLYLVHIAGAYLLNLSRLGLILLLLQYSTEFLFHTA
       :::.:::::::..::.::::: :: ::: ::::::::::..:::.::.:.: .::::: .
NP_001 LHAFPELYFQKTKKEDIPRQLVYIGLYLFHIAGAYLLNLNHLGLVLLVLHYFVEFLFHIS
              100       110       120       130       140       150

             240       250       260       270       280       290 
pF1KSD RLFYFADENNEKLFSAWAAVFGVTRLFILTLAVLAIGFGLARMENQAFDPEKGNFNTLFC
       :::::..:. .: :: ::..: . ::. : :.::..:::::: ::: .:   ::::.:  
NP_001 RLFYFSNEKYQKGFSLWAVLFVLGRLLTLILSVLTVGFGLARAENQKLDFSTGNFNVLAV
              160       170       180       190       200       210

             300       310       320        330       340       350
pF1KSD RLCVLLLVCAAQAWLMWRFIHSQLRHWREYWNEQS-AKRRVPATPRLPARLIKRESGYHE
       :. ::  .:..::..::.::. :::.:::.   :. : .. :.. .  .:  :. .    
NP_001 RIAVLASICVTQAFMMWKFINFQLRRWREHSAFQAPAVKKKPTVTK--GRSSKKGTENGV
              220       230       240       250         260        

              360       370
pF1KSD NGVVKAENGTSPRTKKLKSP
       ::.. .. . :::.:: :: 
NP_001 NGTLTSNVADSPRNKKEKSS
      270       280        

>>XP_016868756 (OMIM: 605190) PREDICTED: translocating c  (278 aa)
 initn: 984 init1: 944 opt: 988  Z-score: 1208.5  bits: 231.8 E(85289): 1.4e-60
Smith-Waterman score: 988; 53.3% identity (79.8% similar) in 272 aa overlap (99-369:8-277)

       70        80        90       100       110       120        
pF1KSD HYGPKDLVTILFYIFITIILHAVVQEYILDKISKRLHLSKVKHSKFNESGQLVVFHFTSV
                                     ::..:.:.::.::::::::::: .:.. . 
XP_016                        MSPSQQQKINRRMHFSKTKHSKFNESGQLSAFYLFAC
                                      10        20        30       

      130       140       150       160       170       180        
pF1KSD IWCFYVVVTEGYLTNPRSLWEDYPHVHLPFQVKFFYLCQLAYWLHALPELYFQKVRKEEI
       .:  .....:.:...:  ::. :::  . ::.::::. ::::::::.:::::::..::.:
XP_016 VWGTFILISENYISDPTILWRAYPHNLMTFQMKFFYISQLAYWLHAFPELYFQKTKKEDI
        40        50        60        70        80        90       

      190       200       210       220       230       240        
pF1KSD PRQLQYICLYLVHIAGAYLLNLSRLGLILLLLQYSTEFLFHTARLFYFADENNEKLFSAW
       :::: :: ::: ::::::::::..:::.::.:.: .::::: .:::::..:. .: :: :
XP_016 PRQLVYIGLYLFHIAGAYLLNLNHLGLVLLVLHYFVEFLFHISRLFYFSNEKYQKGFSLW
       100       110       120       130       140       150       

      250       260       270       280       290       300        
pF1KSD AAVFGVTRLFILTLAVLAIGFGLARMENQAFDPEKGNFNTLFCRLCVLLLVCAAQAWLMW
       :..: . ::. : :.::..:::::: ::: .:   ::::.:  :. ::  .:..::..::
XP_016 AVLFVLGRLLTLILSVLTVGFGLARAENQKLDFSTGNFNVLAVRIAVLASICVTQAFMMW
       160       170       180       190       200       210       

      310       320        330       340       350       360       
pF1KSD RFIHSQLRHWREYWNEQS-AKRRVPATPRLPARLIKRESGYHENGVVKAENGTSPRTKKL
       .::. :::.:::.   :. : .. :.. .  .:  :. .    ::.. .. . :::.:: 
XP_016 KFINFQLRRWREHSAFQAPAVKKKPTVTK--GRSSKKGTENGVNGTLTSNVADSPRNKKE
       220       230       240         250       260       270     

       370
pF1KSD KSP
       :: 
XP_016 KSS
          

>>XP_016868755 (OMIM: 605190) PREDICTED: translocating c  (278 aa)
 initn: 984 init1: 944 opt: 988  Z-score: 1208.5  bits: 231.8 E(85289): 1.4e-60
Smith-Waterman score: 988; 53.3% identity (79.8% similar) in 272 aa overlap (99-369:8-277)

       70        80        90       100       110       120        
pF1KSD HYGPKDLVTILFYIFITIILHAVVQEYILDKISKRLHLSKVKHSKFNESGQLVVFHFTSV
                                     ::..:.:.::.::::::::::: .:.. . 
XP_016                        MSPSQQQKINRRMHFSKTKHSKFNESGQLSAFYLFAC
                                      10        20        30       

      130       140       150       160       170       180        
pF1KSD IWCFYVVVTEGYLTNPRSLWEDYPHVHLPFQVKFFYLCQLAYWLHALPELYFQKVRKEEI
       .:  .....:.:...:  ::. :::  . ::.::::. ::::::::.:::::::..::.:
XP_016 VWGTFILISENYISDPTILWRAYPHNLMTFQMKFFYISQLAYWLHAFPELYFQKTKKEDI
        40        50        60        70        80        90       

      190       200       210       220       230       240        
pF1KSD PRQLQYICLYLVHIAGAYLLNLSRLGLILLLLQYSTEFLFHTARLFYFADENNEKLFSAW
       :::: :: ::: ::::::::::..:::.::.:.: .::::: .:::::..:. .: :: :
XP_016 PRQLVYIGLYLFHIAGAYLLNLNHLGLVLLVLHYFVEFLFHISRLFYFSNEKYQKGFSLW
       100       110       120       130       140       150       

      250       260       270       280       290       300        
pF1KSD AAVFGVTRLFILTLAVLAIGFGLARMENQAFDPEKGNFNTLFCRLCVLLLVCAAQAWLMW
       :..: . ::. : :.::..:::::: ::: .:   ::::.:  :. ::  .:..::..::
XP_016 AVLFVLGRLLTLILSVLTVGFGLARAENQKLDFSTGNFNVLAVRIAVLASICVTQAFMMW
       160       170       180       190       200       210       

      310       320        330       340       350       360       
pF1KSD RFIHSQLRHWREYWNEQS-AKRRVPATPRLPARLIKRESGYHENGVVKAENGTSPRTKKL
       .::. :::.:::.   :. : .. :.. .  .:  :. .    ::.. .. . :::.:: 
XP_016 KFINFQLRRWREHSAFQAPAVKKKPTVTK--GRSSKKGTENGVNGTLTSNVADSPRNKKE
       220       230       240         250       260       270     

       370
pF1KSD KSP
       :: 
XP_016 KSS
          

>>NP_859530 (OMIM: 606920) ceramide synthase 2 [Homo sap  (380 aa)
 initn: 105 init1:  62 opt: 211  Z-score: 261.0  bits: 57.0 E(85289): 8.4e-08
Smith-Waterman score: 211; 25.5% identity (58.8% similar) in 204 aa overlap (113-312:132-328)

             90       100       110       120       130       140  
pF1KSD FITIILHAVVQEYILDKISKRLHLSKVKHSKFNESGQLVVFHFTSVIWCFYVVVTEGYLT
                                     :: :..   .:.. . :  . :.: . .. 
NP_859 LLSRQSGLSGRQVERWFRRRRNQDRPSLLKKFREASWRFTFYLIAFIAGMAVIVDKPWFY
             110       120       130       140       150       160 

            150        160        170       180       190       200
pF1KSD NPRSLWEDYP-HVHLPFQVKFFYLCQLA-YWLHALPELYFQKVRKEEIPRQLQYICLYLV
       . ...:: :: .  .: :  ..:. .:. ::  .:     . :..... .:. .    ..
NP_859 DMKKVWEGYPIQSTIPSQY-WYYMIELSFYW--SLLFSIASDVKRKDFKEQIIHHVATII
             170       180        190         200       210        

              210       220       230       240         250        
pF1KSD HIAGAYLLNLSRLGLILLLLQYSTEFLFHTARLFYFADENN--EKLFSAWAAVFGVTRLF
        :. ... :  : : ... :. :...:...:..: .:  .:  ...: ..: :: .::: 
NP_859 LISFSWFANYIRAGTLIMALHDSSDYLLESAKMFNYAGWKNTCNNIFIVFAIVFIITRLV
      220       230       240       250       260       270        

      260       270       280       290       300       310        
pF1KSD ILTLAVLAIGFGLARMENQAFDPEKGNFNTLFCRLCVLLLVCAAQAWLMWRFIHSQLRHW
       :: . .:   .        ::      ::..   . :: :.    :.:. :. :      
NP_859 ILPFWILHCTLVYPLELYPAFFGYYF-FNSM---MGVLQLLHIFWAYLILRMAHKFITGK
      280       290       300           310       320       330    

      320       330       340       350       360       370
pF1KSD REYWNEQSAKRRVPATPRLPARLIKRESGYHENGVVKAENGTSPRTKKLKSP
                                                           
NP_859 LVEDERSDREETESSEGEEAAAGGGAKSRPLANGHPILNNNHRKND      
          340       350       360       370       380      

>>XP_011507754 (OMIM: 606920) PREDICTED: ceramide syntha  (380 aa)
 initn: 105 init1:  62 opt: 211  Z-score: 261.0  bits: 57.0 E(85289): 8.4e-08
Smith-Waterman score: 211; 25.5% identity (58.8% similar) in 204 aa overlap (113-312:132-328)

             90       100       110       120       130       140  
pF1KSD FITIILHAVVQEYILDKISKRLHLSKVKHSKFNESGQLVVFHFTSVIWCFYVVVTEGYLT
                                     :: :..   .:.. . :  . :.: . .. 
XP_011 LLSRQSGLSGRQVERWFRRRRNQDRPSLLKKFREASWRFTFYLIAFIAGMAVIVDKPWFY
             110       120       130       140       150       160 

            150        160        170       180       190       200
pF1KSD NPRSLWEDYP-HVHLPFQVKFFYLCQLA-YWLHALPELYFQKVRKEEIPRQLQYICLYLV
       . ...:: :: .  .: :  ..:. .:. ::  .:     . :..... .:. .    ..
XP_011 DMKKVWEGYPIQSTIPSQY-WYYMIELSFYW--SLLFSIASDVKRKDFKEQIIHHVATII
             170       180        190         200       210        

              210       220       230       240         250        
pF1KSD HIAGAYLLNLSRLGLILLLLQYSTEFLFHTARLFYFADENN--EKLFSAWAAVFGVTRLF
        :. ... :  : : ... :. :...:...:..: .:  .:  ...: ..: :: .::: 
XP_011 LISFSWFANYIRAGTLIMALHDSSDYLLESAKMFNYAGWKNTCNNIFIVFAIVFIITRLV
      220       230       240       250       260       270        

      260       270       280       290       300       310        
pF1KSD ILTLAVLAIGFGLARMENQAFDPEKGNFNTLFCRLCVLLLVCAAQAWLMWRFIHSQLRHW
       :: . .:   .        ::      ::..   . :: :.    :.:. :. :      
XP_011 ILPFWILHCTLVYPLELYPAFFGYYF-FNSM---MGVLQLLHIFWAYLILRMAHKFITGK
      280       290       300           310       320       330    

      320       330       340       350       360       370
pF1KSD REYWNEQSAKRRVPATPRLPARLIKRESGYHENGVVKAENGTSPRTKKLKSP
                                                           
XP_011 LVEDERSDREETESSEGEEAAAGGGAKSRPLANGHPILNNNHRKND      
          340       350       360       370       380      

>>NP_071358 (OMIM: 606920) ceramide synthase 2 [Homo sap  (380 aa)
 initn: 105 init1:  62 opt: 211  Z-score: 261.0  bits: 57.0 E(85289): 8.4e-08
Smith-Waterman score: 211; 25.5% identity (58.8% similar) in 204 aa overlap (113-312:132-328)

             90       100       110       120       130       140  
pF1KSD FITIILHAVVQEYILDKISKRLHLSKVKHSKFNESGQLVVFHFTSVIWCFYVVVTEGYLT
                                     :: :..   .:.. . :  . :.: . .. 
NP_071 LLSRQSGLSGRQVERWFRRRRNQDRPSLLKKFREASWRFTFYLIAFIAGMAVIVDKPWFY
             110       120       130       140       150       160 

            150        160        170       180       190       200
pF1KSD NPRSLWEDYP-HVHLPFQVKFFYLCQLA-YWLHALPELYFQKVRKEEIPRQLQYICLYLV
       . ...:: :: .  .: :  ..:. .:. ::  .:     . :..... .:. .    ..
NP_071 DMKKVWEGYPIQSTIPSQY-WYYMIELSFYW--SLLFSIASDVKRKDFKEQIIHHVATII
             170       180        190         200       210        

              210       220       230       240         250        
pF1KSD HIAGAYLLNLSRLGLILLLLQYSTEFLFHTARLFYFADENN--EKLFSAWAAVFGVTRLF
        :. ... :  : : ... :. :...:...:..: .:  .:  ...: ..: :: .::: 
NP_071 LISFSWFANYIRAGTLIMALHDSSDYLLESAKMFNYAGWKNTCNNIFIVFAIVFIITRLV
      220       230       240       250       260       270        

      260       270       280       290       300       310        
pF1KSD ILTLAVLAIGFGLARMENQAFDPEKGNFNTLFCRLCVLLLVCAAQAWLMWRFIHSQLRHW
       :: . .:   .        ::      ::..   . :: :.    :.:. :. :      
NP_071 ILPFWILHCTLVYPLELYPAFFGYYF-FNSM---MGVLQLLHIFWAYLILRMAHKFITGK
      280       290       300           310       320       330    

      320       330       340       350       360       370
pF1KSD REYWNEQSAKRRVPATPRLPARLIKRESGYHENGVVKAENGTSPRTKKLKSP
                                                           
NP_071 LVEDERSDREETESSEGEEAAAGGGAKSRPLANGHPILNNNHRKND      
          340       350       360       370       380      




370 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Wed Nov  2 23:40:02 2016 done: Wed Nov  2 23:40:03 2016
 Total Scan time:  6.580 Total Display time:  0.010

Function used was FASTA [36.3.4 Apr, 2011]
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