Result of FASTA (omim) for pF1KSDA0043
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KSDA0043, 726 aa
  1>>>pF1KSDA0043 726 - 726 aa - 726 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 14.7601+/-0.000407; mu= -23.5663+/- 0.025
 mean_var=502.6431+/-103.954, 0's: 0 Z-trim(125.2): 80  B-trim: 477 in 2/60
 Lambda= 0.057206
 statistics sampled from 48183 (48339) to 48183 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.815), E-opt: 0.2 (0.567), width:  16
 Scan time: 11.200

The best scores are:                                      opt bits E(85289)
NP_031397 (OMIM: 601541) bromodomain-containing pr ( 726) 4780 409.1 3.2e-113
XP_006717354 (OMIM: 601541) PREDICTED: bromodomain ( 726) 4780 409.1 3.2e-113
XP_011517354 (OMIM: 601541) PREDICTED: bromodomain ( 726) 4780 409.1 3.2e-113
XP_016870654 (OMIM: 601541) PREDICTED: bromodomain ( 725) 4763 407.7 8.5e-113
XP_016870655 (OMIM: 601541) PREDICTED: bromodomain ( 405) 2604 229.4 2.3e-59
NP_001186385 (OMIM: 601540) bromodomain-containing ( 754) 1971 177.3   2e-43
NP_001106653 (OMIM: 601540) bromodomain-containing ( 801) 1971 177.3 2.1e-43
NP_005095 (OMIM: 601540) bromodomain-containing pr ( 801) 1971 177.3 2.1e-43
NP_001186384 (OMIM: 601540) bromodomain-containing ( 836) 1971 177.3 2.2e-43
NP_001317313 (OMIM: 608749) bromodomain-containing ( 794) 1742 158.4   1e-37
NP_055114 (OMIM: 608749) bromodomain-containing pr ( 722) 1739 158.1 1.1e-37
XP_011526158 (OMIM: 608749) PREDICTED: bromodomain ( 722) 1739 158.1 1.1e-37
NP_490597 (OMIM: 608749) bromodomain-containing pr (1362) 1747 158.9 1.2e-37
XP_011526156 (OMIM: 608749) PREDICTED: bromodomain (1362) 1747 158.9 1.2e-37
NP_001278915 (OMIM: 601540) bromodomain-containing ( 681) 1574 144.5 1.4e-33
NP_001229739 (OMIM: 602144) bromodomain testis-spe ( 874)  953 93.3 4.5e-18
NP_001229736 (OMIM: 602144) bromodomain testis-spe ( 901)  953 93.3 4.6e-18
NP_001229737 (OMIM: 602144) bromodomain testis-spe ( 901)  953 93.3 4.6e-18
NP_001229735 (OMIM: 602144) bromodomain testis-spe ( 951)  735 75.3 1.3e-12
XP_011540335 (OMIM: 602144) PREDICTED: bromodomain ( 947)  722 74.2 2.7e-12
XP_006710919 (OMIM: 602144) PREDICTED: bromodomain ( 947)  722 74.2 2.7e-12
XP_011540337 (OMIM: 602144) PREDICTED: bromodomain ( 947)  722 74.2 2.7e-12
XP_011540338 (OMIM: 602144) PREDICTED: bromodomain ( 947)  722 74.2 2.7e-12
NP_997072 (OMIM: 602144) bromodomain testis-specif ( 947)  722 74.2 2.7e-12
NP_001717 (OMIM: 602144) bromodomain testis-specif ( 947)  722 74.2 2.7e-12
XP_006710918 (OMIM: 602144) PREDICTED: bromodomain ( 947)  722 74.2 2.7e-12
XP_006710916 (OMIM: 602144) PREDICTED: bromodomain ( 947)  722 74.2 2.7e-12
XP_006710920 (OMIM: 602144) PREDICTED: bromodomain ( 947)  722 74.2 2.7e-12
NP_001229734 (OMIM: 602144) bromodomain testis-spe ( 947)  722 74.2 2.7e-12
XP_006710917 (OMIM: 602144) PREDICTED: bromodomain ( 947)  722 74.2 2.7e-12
XP_011540336 (OMIM: 602144) PREDICTED: bromodomain ( 947)  722 74.2 2.7e-12
XP_011540334 (OMIM: 602144) PREDICTED: bromodomain ( 947)  722 74.2 2.7e-12


>>NP_031397 (OMIM: 601541) bromodomain-containing protei  (726 aa)
 initn: 4780 init1: 4780 opt: 4780  Z-score: 2153.6  bits: 409.1 E(85289): 3.2e-113
Smith-Waterman score: 4780; 100.0% identity (100.0% similar) in 726 aa overlap (1-726:1-726)

               10        20        30        40        50        60
pF1KSD MSTATTVAPAGIPATPGPVNPPPPEVSNPSKPGRKTNQLQYMQNVVVKTLWKHQFAWPFY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_031 MSTATTVAPAGIPATPGPVNPPPPEVSNPSKPGRKTNQLQYMQNVVVKTLWKHQFAWPFY
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KSD QPVDAIKLNLPDYHKIIKNPMDMGTIKKRLENNYYWSASECMQDFNTMFTNCYIYNKPTD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_031 QPVDAIKLNLPDYHKIIKNPMDMGTIKKRLENNYYWSASECMQDFNTMFTNCYIYNKPTD
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KSD DIVLMAQALEKIFLQKVAQMPQEEVELLPPAPKGKGRKPAAGAQSAGTQQVAAVSSVSPA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_031 DIVLMAQALEKIFLQKVAQMPQEEVELLPPAPKGKGRKPAAGAQSAGTQQVAAVSSVSPA
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KSD TPFQSVPPTVSQTPVIAATPVPTITANVTSVPVPPAAAPPPPATPIVPVVPPTPPVVKKK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_031 TPFQSVPPTVSQTPVIAATPVPTITANVTSVPVPPAAAPPPPATPIVPVVPPTPPVVKKK
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KSD GVKRKADTTTPTTSAITASRSESPPPLSDPKQAKVVARRESGGRPIKPPKKDLEDGEVPQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_031 GVKRKADTTTPTTSAITASRSESPPPLSDPKQAKVVARRESGGRPIKPPKKDLEDGEVPQ
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KSD HAGKKGKLSEHLRYCDSILREMLSKKHAAYAWPFYKPVDAEALELHDYHDIIKHPMDLST
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_031 HAGKKGKLSEHLRYCDSILREMLSKKHAAYAWPFYKPVDAEALELHDYHDIIKHPMDLST
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KSD VKRKMDGREYPDAQGFAADVRLMFSNCYKYNPPDHEVVAMARKLQDVFEMRFAKMPDEPV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_031 VKRKMDGREYPDAQGFAADVRLMFSNCYKYNPPDHEVVAMARKLQDVFEMRFAKMPDEPV
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KSD EAPALPAPAAPMVSKGAESSRSSEESSSDSGSSDSEEERATRLAELQEQLKAVHEQLAAL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_031 EAPALPAPAAPMVSKGAESSRSSEESSSDSGSSDSEEERATRLAELQEQLKAVHEQLAAL
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KSD SQAPVNKPKKKKEKKEKEKKKKDKEKEKEKHKVKAEEEKKAKVAPPAKQAQQKKAPAKKA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_031 SQAPVNKPKKKKEKKEKEKKKKDKEKEKEKHKVKAEEEKKAKVAPPAKQAQQKKAPAKKA
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KSD NSTTTAGRQLKKGGKQASASYDSEEEEEGLPMSYDEKRQLSLDINRLPGEKLGRVVHIIQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_031 NSTTTAGRQLKKGGKQASASYDSEEEEEGLPMSYDEKRQLSLDINRLPGEKLGRVVHIIQ
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KSD SREPSLRDSNPDEIEIDFETLKPTTLRELERYVKSCLQKKQRKPFSASGKKQAAKSKEEL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_031 SREPSLRDSNPDEIEIDFETLKPTTLRELERYVKSCLQKKQRKPFSASGKKQAAKSKEEL
              610       620       630       640       650       660

              670       680       690       700       710       720
pF1KSD AQEKKKELEKRLQDVSGQLSSSKKPARKEKPGSAPSGGPSRLSSSSSSESGSSSSSGSSS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_031 AQEKKKELEKRLQDVSGQLSSSKKPARKEKPGSAPSGGPSRLSSSSSSESGSSSSSGSSS
              670       680       690       700       710       720

             
pF1KSD DSSDSE
       ::::::
NP_031 DSSDSE
             

>>XP_006717354 (OMIM: 601541) PREDICTED: bromodomain-con  (726 aa)
 initn: 4780 init1: 4780 opt: 4780  Z-score: 2153.6  bits: 409.1 E(85289): 3.2e-113
Smith-Waterman score: 4780; 100.0% identity (100.0% similar) in 726 aa overlap (1-726:1-726)

               10        20        30        40        50        60
pF1KSD MSTATTVAPAGIPATPGPVNPPPPEVSNPSKPGRKTNQLQYMQNVVVKTLWKHQFAWPFY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 MSTATTVAPAGIPATPGPVNPPPPEVSNPSKPGRKTNQLQYMQNVVVKTLWKHQFAWPFY
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KSD QPVDAIKLNLPDYHKIIKNPMDMGTIKKRLENNYYWSASECMQDFNTMFTNCYIYNKPTD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 QPVDAIKLNLPDYHKIIKNPMDMGTIKKRLENNYYWSASECMQDFNTMFTNCYIYNKPTD
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KSD DIVLMAQALEKIFLQKVAQMPQEEVELLPPAPKGKGRKPAAGAQSAGTQQVAAVSSVSPA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 DIVLMAQALEKIFLQKVAQMPQEEVELLPPAPKGKGRKPAAGAQSAGTQQVAAVSSVSPA
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KSD TPFQSVPPTVSQTPVIAATPVPTITANVTSVPVPPAAAPPPPATPIVPVVPPTPPVVKKK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 TPFQSVPPTVSQTPVIAATPVPTITANVTSVPVPPAAAPPPPATPIVPVVPPTPPVVKKK
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KSD GVKRKADTTTPTTSAITASRSESPPPLSDPKQAKVVARRESGGRPIKPPKKDLEDGEVPQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 GVKRKADTTTPTTSAITASRSESPPPLSDPKQAKVVARRESGGRPIKPPKKDLEDGEVPQ
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KSD HAGKKGKLSEHLRYCDSILREMLSKKHAAYAWPFYKPVDAEALELHDYHDIIKHPMDLST
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 HAGKKGKLSEHLRYCDSILREMLSKKHAAYAWPFYKPVDAEALELHDYHDIIKHPMDLST
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KSD VKRKMDGREYPDAQGFAADVRLMFSNCYKYNPPDHEVVAMARKLQDVFEMRFAKMPDEPV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 VKRKMDGREYPDAQGFAADVRLMFSNCYKYNPPDHEVVAMARKLQDVFEMRFAKMPDEPV
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KSD EAPALPAPAAPMVSKGAESSRSSEESSSDSGSSDSEEERATRLAELQEQLKAVHEQLAAL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 EAPALPAPAAPMVSKGAESSRSSEESSSDSGSSDSEEERATRLAELQEQLKAVHEQLAAL
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KSD SQAPVNKPKKKKEKKEKEKKKKDKEKEKEKHKVKAEEEKKAKVAPPAKQAQQKKAPAKKA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 SQAPVNKPKKKKEKKEKEKKKKDKEKEKEKHKVKAEEEKKAKVAPPAKQAQQKKAPAKKA
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KSD NSTTTAGRQLKKGGKQASASYDSEEEEEGLPMSYDEKRQLSLDINRLPGEKLGRVVHIIQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 NSTTTAGRQLKKGGKQASASYDSEEEEEGLPMSYDEKRQLSLDINRLPGEKLGRVVHIIQ
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KSD SREPSLRDSNPDEIEIDFETLKPTTLRELERYVKSCLQKKQRKPFSASGKKQAAKSKEEL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 SREPSLRDSNPDEIEIDFETLKPTTLRELERYVKSCLQKKQRKPFSASGKKQAAKSKEEL
              610       620       630       640       650       660

              670       680       690       700       710       720
pF1KSD AQEKKKELEKRLQDVSGQLSSSKKPARKEKPGSAPSGGPSRLSSSSSSESGSSSSSGSSS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 AQEKKKELEKRLQDVSGQLSSSKKPARKEKPGSAPSGGPSRLSSSSSSESGSSSSSGSSS
              670       680       690       700       710       720

             
pF1KSD DSSDSE
       ::::::
XP_006 DSSDSE
             

>>XP_011517354 (OMIM: 601541) PREDICTED: bromodomain-con  (726 aa)
 initn: 4780 init1: 4780 opt: 4780  Z-score: 2153.6  bits: 409.1 E(85289): 3.2e-113
Smith-Waterman score: 4780; 100.0% identity (100.0% similar) in 726 aa overlap (1-726:1-726)

               10        20        30        40        50        60
pF1KSD MSTATTVAPAGIPATPGPVNPPPPEVSNPSKPGRKTNQLQYMQNVVVKTLWKHQFAWPFY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MSTATTVAPAGIPATPGPVNPPPPEVSNPSKPGRKTNQLQYMQNVVVKTLWKHQFAWPFY
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KSD QPVDAIKLNLPDYHKIIKNPMDMGTIKKRLENNYYWSASECMQDFNTMFTNCYIYNKPTD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QPVDAIKLNLPDYHKIIKNPMDMGTIKKRLENNYYWSASECMQDFNTMFTNCYIYNKPTD
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KSD DIVLMAQALEKIFLQKVAQMPQEEVELLPPAPKGKGRKPAAGAQSAGTQQVAAVSSVSPA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DIVLMAQALEKIFLQKVAQMPQEEVELLPPAPKGKGRKPAAGAQSAGTQQVAAVSSVSPA
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KSD TPFQSVPPTVSQTPVIAATPVPTITANVTSVPVPPAAAPPPPATPIVPVVPPTPPVVKKK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TPFQSVPPTVSQTPVIAATPVPTITANVTSVPVPPAAAPPPPATPIVPVVPPTPPVVKKK
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KSD GVKRKADTTTPTTSAITASRSESPPPLSDPKQAKVVARRESGGRPIKPPKKDLEDGEVPQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GVKRKADTTTPTTSAITASRSESPPPLSDPKQAKVVARRESGGRPIKPPKKDLEDGEVPQ
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KSD HAGKKGKLSEHLRYCDSILREMLSKKHAAYAWPFYKPVDAEALELHDYHDIIKHPMDLST
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HAGKKGKLSEHLRYCDSILREMLSKKHAAYAWPFYKPVDAEALELHDYHDIIKHPMDLST
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KSD VKRKMDGREYPDAQGFAADVRLMFSNCYKYNPPDHEVVAMARKLQDVFEMRFAKMPDEPV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VKRKMDGREYPDAQGFAADVRLMFSNCYKYNPPDHEVVAMARKLQDVFEMRFAKMPDEPV
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KSD EAPALPAPAAPMVSKGAESSRSSEESSSDSGSSDSEEERATRLAELQEQLKAVHEQLAAL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EAPALPAPAAPMVSKGAESSRSSEESSSDSGSSDSEEERATRLAELQEQLKAVHEQLAAL
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KSD SQAPVNKPKKKKEKKEKEKKKKDKEKEKEKHKVKAEEEKKAKVAPPAKQAQQKKAPAKKA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SQAPVNKPKKKKEKKEKEKKKKDKEKEKEKHKVKAEEEKKAKVAPPAKQAQQKKAPAKKA
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KSD NSTTTAGRQLKKGGKQASASYDSEEEEEGLPMSYDEKRQLSLDINRLPGEKLGRVVHIIQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NSTTTAGRQLKKGGKQASASYDSEEEEEGLPMSYDEKRQLSLDINRLPGEKLGRVVHIIQ
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KSD SREPSLRDSNPDEIEIDFETLKPTTLRELERYVKSCLQKKQRKPFSASGKKQAAKSKEEL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SREPSLRDSNPDEIEIDFETLKPTTLRELERYVKSCLQKKQRKPFSASGKKQAAKSKEEL
              610       620       630       640       650       660

              670       680       690       700       710       720
pF1KSD AQEKKKELEKRLQDVSGQLSSSKKPARKEKPGSAPSGGPSRLSSSSSSESGSSSSSGSSS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AQEKKKELEKRLQDVSGQLSSSKKPARKEKPGSAPSGGPSRLSSSSSSESGSSSSSGSSS
              670       680       690       700       710       720

             
pF1KSD DSSDSE
       ::::::
XP_011 DSSDSE
             

>>XP_016870654 (OMIM: 601541) PREDICTED: bromodomain-con  (725 aa)
 initn: 4799 init1: 4372 opt: 4763  Z-score: 2146.0  bits: 407.7 E(85289): 8.5e-113
Smith-Waterman score: 4763; 99.9% identity (99.9% similar) in 726 aa overlap (1-726:1-725)

               10        20        30        40        50        60
pF1KSD MSTATTVAPAGIPATPGPVNPPPPEVSNPSKPGRKTNQLQYMQNVVVKTLWKHQFAWPFY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MSTATTVAPAGIPATPGPVNPPPPEVSNPSKPGRKTNQLQYMQNVVVKTLWKHQFAWPFY
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KSD QPVDAIKLNLPDYHKIIKNPMDMGTIKKRLENNYYWSASECMQDFNTMFTNCYIYNKPTD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QPVDAIKLNLPDYHKIIKNPMDMGTIKKRLENNYYWSASECMQDFNTMFTNCYIYNKPTD
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KSD DIVLMAQALEKIFLQKVAQMPQEEVELLPPAPKGKGRKPAAGAQSAGTQQVAAVSSVSPA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DIVLMAQALEKIFLQKVAQMPQEEVELLPPAPKGKGRKPAAGAQSAGTQQVAAVSSVSPA
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KSD TPFQSVPPTVSQTPVIAATPVPTITANVTSVPVPPAAAPPPPATPIVPVVPPTPPVVKKK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TPFQSVPPTVSQTPVIAATPVPTITANVTSVPVPPAAAPPPPATPIVPVVPPTPPVVKKK
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KSD GVKRKADTTTPTTSAITASRSESPPPLSDPKQAKVVARRESGGRPIKPPKKDLEDGEVPQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GVKRKADTTTPTTSAITASRSESPPPLSDPKQAKVVARRESGGRPIKPPKKDLEDGEVPQ
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KSD HAGKKGKLSEHLRYCDSILREMLSKKHAAYAWPFYKPVDAEALELHDYHDIIKHPMDLST
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HAGKKGKLSEHLRYCDSILREMLSKKHAAYAWPFYKPVDAEALELHDYHDIIKHPMDLST
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KSD VKRKMDGREYPDAQGFAADVRLMFSNCYKYNPPDHEVVAMARKLQDVFEMRFAKMPDEPV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VKRKMDGREYPDAQGFAADVRLMFSNCYKYNPPDHEVVAMARKLQDVFEMRFAKMPDEPV
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KSD EAPALPAPAAPMVSKGAESSRSSEESSSDSGSSDSEEERATRLAELQEQLKAVHEQLAAL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EAPALPAPAAPMVSKGAESSRSSEESSSDSGSSDSEEERATRLAELQEQLKAVHEQLAAL
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KSD SQAPVNKPKKKKEKKEKEKKKKDKEKEKEKHKVKAEEEKKAKVAPPAKQAQQKKAPAKKA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SQAPVNKPKKKKEKKEKEKKKKDKEKEKEKHKVKAEEEKKAKVAPPAKQAQQKKAPAKKA
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KSD NSTTTAGRQLKKGGKQASASYDSEEEEEGLPMSYDEKRQLSLDINRLPGEKLGRVVHIIQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NSTTTAGRQLKKGGKQASASYDSEEEEEGLPMSYDEKRQLSLDINRLPGEKLGRVVHIIQ
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KSD SREPSLRDSNPDEIEIDFETLKPTTLRELERYVKSCLQKKQRKPFSASGKKQAAKSKEEL
       :::::::::::::::::::::::::::::::::::::::::::::: :::::::::::::
XP_016 SREPSLRDSNPDEIEIDFETLKPTTLRELERYVKSCLQKKQRKPFS-SGKKQAAKSKEEL
              610       620       630       640        650         

              670       680       690       700       710       720
pF1KSD AQEKKKELEKRLQDVSGQLSSSKKPARKEKPGSAPSGGPSRLSSSSSSESGSSSSSGSSS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AQEKKKELEKRLQDVSGQLSSSKKPARKEKPGSAPSGGPSRLSSSSSSESGSSSSSGSSS
     660       670       680       690       700       710         

             
pF1KSD DSSDSE
       ::::::
XP_016 DSSDSE
     720     

>>XP_016870655 (OMIM: 601541) PREDICTED: bromodomain-con  (405 aa)
 initn: 2604 init1: 2604 opt: 2604  Z-score: 1186.9  bits: 229.4 E(85289): 2.3e-59
Smith-Waterman score: 2604; 100.0% identity (100.0% similar) in 405 aa overlap (322-726:1-405)

             300       310       320       330       340       350 
pF1KSD DLEDGEVPQHAGKKGKLSEHLRYCDSILREMLSKKHAAYAWPFYKPVDAEALELHDYHDI
                                     ::::::::::::::::::::::::::::::
XP_016                               MLSKKHAAYAWPFYKPVDAEALELHDYHDI
                                             10        20        30

             360       370       380       390       400       410 
pF1KSD IKHPMDLSTVKRKMDGREYPDAQGFAADVRLMFSNCYKYNPPDHEVVAMARKLQDVFEMR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IKHPMDLSTVKRKMDGREYPDAQGFAADVRLMFSNCYKYNPPDHEVVAMARKLQDVFEMR
               40        50        60        70        80        90

             420       430       440       450       460       470 
pF1KSD FAKMPDEPVEAPALPAPAAPMVSKGAESSRSSEESSSDSGSSDSEEERATRLAELQEQLK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FAKMPDEPVEAPALPAPAAPMVSKGAESSRSSEESSSDSGSSDSEEERATRLAELQEQLK
              100       110       120       130       140       150

             480       490       500       510       520       530 
pF1KSD AVHEQLAALSQAPVNKPKKKKEKKEKEKKKKDKEKEKEKHKVKAEEEKKAKVAPPAKQAQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AVHEQLAALSQAPVNKPKKKKEKKEKEKKKKDKEKEKEKHKVKAEEEKKAKVAPPAKQAQ
              160       170       180       190       200       210

             540       550       560       570       580       590 
pF1KSD QKKAPAKKANSTTTAGRQLKKGGKQASASYDSEEEEEGLPMSYDEKRQLSLDINRLPGEK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QKKAPAKKANSTTTAGRQLKKGGKQASASYDSEEEEEGLPMSYDEKRQLSLDINRLPGEK
              220       230       240       250       260       270

             600       610       620       630       640       650 
pF1KSD LGRVVHIIQSREPSLRDSNPDEIEIDFETLKPTTLRELERYVKSCLQKKQRKPFSASGKK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LGRVVHIIQSREPSLRDSNPDEIEIDFETLKPTTLRELERYVKSCLQKKQRKPFSASGKK
              280       290       300       310       320       330

             660       670       680       690       700       710 
pF1KSD QAAKSKEELAQEKKKELEKRLQDVSGQLSSSKKPARKEKPGSAPSGGPSRLSSSSSSESG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QAAKSKEELAQEKKKELEKRLQDVSGQLSSSKKPARKEKPGSAPSGGPSRLSSSSSSESG
              340       350       360       370       380       390

             720      
pF1KSD SSSSSGSSSDSSDSE
       :::::::::::::::
XP_016 SSSSSGSSSDSSDSE
              400     

>>NP_001186385 (OMIM: 601540) bromodomain-containing pro  (754 aa)
 initn: 2642 init1: 961 opt: 1971  Z-score: 900.5  bits: 177.3 E(85289): 2e-43
Smith-Waterman score: 2903; 63.5% identity (79.2% similar) in 761 aa overlap (10-723:2-749)

               10         20        30        40        50         
pF1KSD MSTATTVAPAGIPATP-GPVNPPPPEVSNPSKPGRKTNQLQYMQNVVVKTLWKHQFAWPF
                :..::    :.::::::::::.:::: ::::::...::.:.::::::::::
NP_001         MASVPALQLTPANPPPPEVSNPKKPGRVTNQLQYLHKVVMKALWKHQFAWPF
                       10        20        30        40        50  

      60        70        80        90       100       110         
pF1KSD YQPVDAIKLNLPDYHKIIKNPMDMGTIKKRLENNYYWSASECMQDFNTMFTNCYIYNKPT
        :::::.::.:::::::::.::::::::.::::::::.::::::::::::::::::::::
NP_001 RQPVDAVKLGLPDYHKIIKQPMDMGTIKRRLENNYYWAASECMQDFNTMFTNCYIYNKPT
             60        70        80        90       100       110  

     120       130       140       150       160           170     
pF1KSD DDIVLMAQALEKIFLQKVAQMPQEEVELLPPAPKGKGRKPAAGAQSAGT----QQVAAVS
       ::::::::.::::::::::.::::: ::.   ::.. .: :  :   :.    .:: :::
NP_001 DDIVLMAQTLEKIFLQKVASMPQEEQELVVTIPKNSHKKGAKLAALQGSVTSAHQVPAVS
            120       130       140       150       160       170  

         180       190       200       210       220       230     
pF1KSD SVSPATPFQSVPPTVSQTPVIAATPVPTITANVTSVPVPPAAAPPPPATPIVPVVPPTPP
       :::  : . . :: .  :  .   : :.    : : :.  .     :    : ..::. :
NP_001 SVSH-TALYTPPPEIPTT--VLNIPHPS----VISSPLLKSLHSAGPPLLAVTAAPPAQP
             180         190           200       210       220     

         240       250       260        270       280       290    
pF1KSD VVKKKGVKRKADTTTPTTSAITASRSESPPPLS-DPKQAKVVARRESGGRPIKPPKKDLE
       ..::::::::::::::: .:: :  : . :: : .:: :..   :. .:::::::.::: 
NP_001 LAKKKGVKRKADTTTPTPTAILAPGSPASPPGSLEPKAARLPPMRRESGRPIKPPRKDLP
         230       240       250       260       270       280     

          300       310       320       330       340       350    
pF1KSD DGEVPQHAGKKGKLSEHLRYCDSILREMLSKKHAAYAWPFYKPVDAEALELHDYHDIIKH
       :..  ....:::::::.:..:..::.:.:::::::::::::::::: :: ::::::::::
NP_001 DSQQQHQSSKKGKLSEQLKHCNGILKELLSKKHAAYAWPFYKPVDASALGLHDYHDIIKH
         290       300       310       320       330       340     

          360       370       380       390       400       410    
pF1KSD PMDLSTVKRKMDGREYPDAQGFAADVRLMFSNCYKYNPPDHEVVAMARKLQDVFEMRFAK
       :::::::::::..:.: ::: ::::::::::::::::::::.:::::::::::::.:.::
NP_001 PMDLSTVKRKMENRDYRDAQEFAADVRLMFSNCYKYNPPDHDVVAMARKLQDVFEFRYAK
         350       360       370       380       390       400     

          420       430         440       450                      
pF1KSD MPDEPVEAPALPAPAA--PMVSKGAESSRSSEESSSDSGS------------------SD
       :::::.:   ::. .:  : ..:..  : :::::::.:.:                  ::
NP_001 MPDEPLEPGPLPVSTAMPPGLAKSSSES-SSEESSSESSSEEEEEEDEEDEEEEESESSD
         410       420       430        440       450       460    

          460       470       480       490       500       510    
pF1KSD SEEERATRLAELQEQLKAVHEQLAALSQAPVNKPKKKKEKKEKEKKKKDKEKEKEKHKVK
       :::::: :::::::::.:::::::::::.:..:::.:.:::::.::.:    ::.. .. 
NP_001 SEEERAHRLAELQEQLRAVHEQLAALSQGPISKPKRKREKKEKKKKRK---AEKHRGRAG
          470       480       490       500       510          520 

          520        530       540                 550        560  
pF1KSD AEEEKKAKVAP-PAKQAQQKKAPAKKANSTTT----------AGRQL-KKGGKQASAS--
       :.:. :.  :: : .  ..::: .. ..:..           .: .: ::. : :  .  
NP_001 ADEDDKGPRAPRPPQPKKSKKASGSGGGSAALGPSGFGPSGGSGTKLPKKATKTAPPALP
             530       540       550       560       570       580 

                570       580       590       600       610        
pF1KSD --YDSEEEEEGLPMSYDEKRQLSLDINRLPGEKLGRVVHIIQSREPSLRDSNPDEIEIDF
         ::::::::. :::::::::::::::.::::::::::::::.::::::::::.::::::
NP_001 TGYDSEEEEESRPMSYDEKRQLSLDINKLPGEKLGRVVHIIQAREPSLRDSNPEEIEIDF
             590       600       610       620       630       640 

      620       630       640       650       660       670        
pF1KSD ETLKPTTLRELERYVKSCLQKKQRKPFSASGKKQAAKSKEELAQEKKKELEKRLQDVSGQ
       :::::.::::::::: :::.:: :::..   :: ..:.::::: :::.::::::::::::
NP_001 ETLKPSTLRELERYVLSCLRKKPRKPYTI--KKPVGKTKEELALEKKRELEKRLQDVSGQ
             650       660       670         680       690         

      680         690         700        710       720        
pF1KSD LSSSKKPARK--EKP--GSAPSGGPSRLS-SSSSSESGSSSSSGSSSDSSDSE  
       :.:.::: .:  ::   .:: . . :::: :::::.:.:::::.::::.:     
NP_001 LNSTKKPPKKANEKTESSSAQQVAVSRLSASSSSSDSSSSSSSSSSSDTSDSDSG
     700       710       720       730       740       750    

>>NP_001106653 (OMIM: 601540) bromodomain-containing pro  (801 aa)
 initn: 2642 init1: 961 opt: 1971  Z-score: 900.1  bits: 177.3 E(85289): 2.1e-43
Smith-Waterman score: 2903; 63.5% identity (79.2% similar) in 761 aa overlap (10-723:49-796)

                                    10         20        30        
pF1KSD                      MSTATTVAPAGIPATP-GPVNPPPPEVSNPSKPGRKTNQ
                                     :..::    :.::::::::::.:::: :::
NP_001 LLGLGPEAAAPGKRIRKPSLLYEGFESPTMASVPALQLTPANPPPPEVSNPKKPGRVTNQ
       20        30        40        50        60        70        

       40        50        60        70        80        90        
pF1KSD LQYMQNVVVKTLWKHQFAWPFYQPVDAIKLNLPDYHKIIKNPMDMGTIKKRLENNYYWSA
       :::...::.:.:::::::::: :::::.::.:::::::::.::::::::.::::::::.:
NP_001 LQYLHKVVMKALWKHQFAWPFRQPVDAVKLGLPDYHKIIKQPMDMGTIKRRLENNYYWAA
       80        90       100       110       120       130        

      100       110       120       130       140       150        
pF1KSD SECMQDFNTMFTNCYIYNKPTDDIVLMAQALEKIFLQKVAQMPQEEVELLPPAPKGKGRK
       :::::::::::::::::::::::::::::.::::::::::.::::: ::.   ::.. .:
NP_001 SECMQDFNTMFTNCYIYNKPTDDIVLMAQTLEKIFLQKVASMPQEEQELVVTIPKNSHKK
      140       150       160       170       180       190        

      160           170       180       190       200       210    
pF1KSD PAAGAQSAGT----QQVAAVSSVSPATPFQSVPPTVSQTPVIAATPVPTITANVTSVPVP
        :  :   :.    .:: ::::::  : . . :: .  :  .   : :.    : : :. 
NP_001 GAKLAALQGSVTSAHQVPAVSSVSH-TALYTPPPEIPTT--VLNIPHPS----VISSPLL
      200       210       220        230         240           250 

          220       230       240       250       260        270   
pF1KSD PAAAPPPPATPIVPVVPPTPPVVKKKGVKRKADTTTPTTSAITASRSESPPPLS-DPKQA
        .     :    : ..::. :..::::::::::::::: .:: :  : . :: : .:: :
NP_001 KSLHSAGPPLLAVTAAPPAQPLAKKKGVKRKADTTTPTPTAILAPGSPASPPGSLEPKAA
             260       270       280       290       300       310 

           280       290       300       310       320       330   
pF1KSD KVVARRESGGRPIKPPKKDLEDGEVPQHAGKKGKLSEHLRYCDSILREMLSKKHAAYAWP
       ..   :. .:::::::.::: :..  ....:::::::.:..:..::.:.:::::::::::
NP_001 RLPPMRRESGRPIKPPRKDLPDSQQQHQSSKKGKLSEQLKHCNGILKELLSKKHAAYAWP
             320       330       340       350       360       370 

           340       350       360       370       380       390   
pF1KSD FYKPVDAEALELHDYHDIIKHPMDLSTVKRKMDGREYPDAQGFAADVRLMFSNCYKYNPP
       ::::::: :: :::::::::::::::::::::..:.: ::: ::::::::::::::::::
NP_001 FYKPVDASALGLHDYHDIIKHPMDLSTVKRKMENRDYRDAQEFAADVRLMFSNCYKYNPP
             380       390       400       410       420       430 

           400       410       420       430         440       450 
pF1KSD DHEVVAMARKLQDVFEMRFAKMPDEPVEAPALPAPAA--PMVSKGAESSRSSEESSSDSG
       ::.:::::::::::::.:.:::::::.:   ::. .:  : ..:..  : :::::::.:.
NP_001 DHDVVAMARKLQDVFEFRYAKMPDEPLEPGPLPVSTAMPPGLAKSSSES-SSEESSSESS
             440       450       460       470       480        490

                               460       470       480       490   
pF1KSD S------------------SDSEEERATRLAELQEQLKAVHEQLAALSQAPVNKPKKKKE
       :                  :::::::: :::::::::.:::::::::::.:..:::.:.:
NP_001 SEEEEEEDEEDEEEEESESSDSEEERAHRLAELQEQLRAVHEQLAALSQGPISKPKRKRE
              500       510       520       530       540       550

           500       510       520        530       540            
pF1KSD KKEKEKKKKDKEKEKEKHKVKAEEEKKAKVAP-PAKQAQQKKAPAKKANSTTT-------
       ::::.::.:    ::.. .. :.:. :.  :: : .  ..::: .. ..:..        
NP_001 KKEKKKKRK---AEKHRGRAGADEDDKGPRAPRPPQPKKSKKASGSGGGSAALGPSGFGP
                 560       570       580       590       600       

            550        560           570       580       590       
pF1KSD ---AGRQL-KKGGKQASAS----YDSEEEEEGLPMSYDEKRQLSLDINRLPGEKLGRVVH
          .: .: ::. : :  .    ::::::::. :::::::::::::::.:::::::::::
NP_001 SGGSGTKLPKKATKTAPPALPTGYDSEEEEESRPMSYDEKRQLSLDINKLPGEKLGRVVH
       610       620       630       640       650       660       

       600       610       620       630       640       650       
pF1KSD IIQSREPSLRDSNPDEIEIDFETLKPTTLRELERYVKSCLQKKQRKPFSASGKKQAAKSK
       :::.::::::::::.:::::::::::.::::::::: :::.:: :::..   :: ..:.:
NP_001 IIQAREPSLRDSNPEEIEIDFETLKPSTLRELERYVLSCLRKKPRKPYTI--KKPVGKTK
       670       680       690       700       710         720     

       660       670       680         690         700        710  
pF1KSD EELAQEKKKELEKRLQDVSGQLSSSKKPARK--EKP--GSAPSGGPSRLS-SSSSSESGS
       :::: :::.:::::::::::::.:.::: .:  ::   .:: . . :::: :::::.:.:
NP_001 EELALEKKRELEKRLQDVSGQLNSTKKPPKKANEKTESSSAQQVAVSRLSASSSSSDSSS
         730       740       750       760       770       780     

            720        
pF1KSD SSSSGSSSDSSDSE  
       ::::.::::.:     
NP_001 SSSSSSSSDTSDSDSG
         790       800 

>>NP_005095 (OMIM: 601540) bromodomain-containing protei  (801 aa)
 initn: 2642 init1: 961 opt: 1971  Z-score: 900.1  bits: 177.3 E(85289): 2.1e-43
Smith-Waterman score: 2903; 63.5% identity (79.2% similar) in 761 aa overlap (10-723:49-796)

                                    10         20        30        
pF1KSD                      MSTATTVAPAGIPATP-GPVNPPPPEVSNPSKPGRKTNQ
                                     :..::    :.::::::::::.:::: :::
NP_005 LLGLGPEAAAPGKRIRKPSLLYEGFESPTMASVPALQLTPANPPPPEVSNPKKPGRVTNQ
       20        30        40        50        60        70        

       40        50        60        70        80        90        
pF1KSD LQYMQNVVVKTLWKHQFAWPFYQPVDAIKLNLPDYHKIIKNPMDMGTIKKRLENNYYWSA
       :::...::.:.:::::::::: :::::.::.:::::::::.::::::::.::::::::.:
NP_005 LQYLHKVVMKALWKHQFAWPFRQPVDAVKLGLPDYHKIIKQPMDMGTIKRRLENNYYWAA
       80        90       100       110       120       130        

      100       110       120       130       140       150        
pF1KSD SECMQDFNTMFTNCYIYNKPTDDIVLMAQALEKIFLQKVAQMPQEEVELLPPAPKGKGRK
       :::::::::::::::::::::::::::::.::::::::::.::::: ::.   ::.. .:
NP_005 SECMQDFNTMFTNCYIYNKPTDDIVLMAQTLEKIFLQKVASMPQEEQELVVTIPKNSHKK
      140       150       160       170       180       190        

      160           170       180       190       200       210    
pF1KSD PAAGAQSAGT----QQVAAVSSVSPATPFQSVPPTVSQTPVIAATPVPTITANVTSVPVP
        :  :   :.    .:: ::::::  : . . :: .  :  .   : :.    : : :. 
NP_005 GAKLAALQGSVTSAHQVPAVSSVSH-TALYTPPPEIPTT--VLNIPHPS----VISSPLL
      200       210       220        230         240           250 

          220       230       240       250       260        270   
pF1KSD PAAAPPPPATPIVPVVPPTPPVVKKKGVKRKADTTTPTTSAITASRSESPPPLS-DPKQA
        .     :    : ..::. :..::::::::::::::: .:: :  : . :: : .:: :
NP_005 KSLHSAGPPLLAVTAAPPAQPLAKKKGVKRKADTTTPTPTAILAPGSPASPPGSLEPKAA
             260       270       280       290       300       310 

           280       290       300       310       320       330   
pF1KSD KVVARRESGGRPIKPPKKDLEDGEVPQHAGKKGKLSEHLRYCDSILREMLSKKHAAYAWP
       ..   :. .:::::::.::: :..  ....:::::::.:..:..::.:.:::::::::::
NP_005 RLPPMRRESGRPIKPPRKDLPDSQQQHQSSKKGKLSEQLKHCNGILKELLSKKHAAYAWP
             320       330       340       350       360       370 

           340       350       360       370       380       390   
pF1KSD FYKPVDAEALELHDYHDIIKHPMDLSTVKRKMDGREYPDAQGFAADVRLMFSNCYKYNPP
       ::::::: :: :::::::::::::::::::::..:.: ::: ::::::::::::::::::
NP_005 FYKPVDASALGLHDYHDIIKHPMDLSTVKRKMENRDYRDAQEFAADVRLMFSNCYKYNPP
             380       390       400       410       420       430 

           400       410       420       430         440       450 
pF1KSD DHEVVAMARKLQDVFEMRFAKMPDEPVEAPALPAPAA--PMVSKGAESSRSSEESSSDSG
       ::.:::::::::::::.:.:::::::.:   ::. .:  : ..:..  : :::::::.:.
NP_005 DHDVVAMARKLQDVFEFRYAKMPDEPLEPGPLPVSTAMPPGLAKSSSES-SSEESSSESS
             440       450       460       470       480        490

                               460       470       480       490   
pF1KSD S------------------SDSEEERATRLAELQEQLKAVHEQLAALSQAPVNKPKKKKE
       :                  :::::::: :::::::::.:::::::::::.:..:::.:.:
NP_005 SEEEEEEDEEDEEEEESESSDSEEERAHRLAELQEQLRAVHEQLAALSQGPISKPKRKRE
              500       510       520       530       540       550

           500       510       520        530       540            
pF1KSD KKEKEKKKKDKEKEKEKHKVKAEEEKKAKVAP-PAKQAQQKKAPAKKANSTTT-------
       ::::.::.:    ::.. .. :.:. :.  :: : .  ..::: .. ..:..        
NP_005 KKEKKKKRK---AEKHRGRAGADEDDKGPRAPRPPQPKKSKKASGSGGGSAALGPSGFGP
                 560       570       580       590       600       

            550        560           570       580       590       
pF1KSD ---AGRQL-KKGGKQASAS----YDSEEEEEGLPMSYDEKRQLSLDINRLPGEKLGRVVH
          .: .: ::. : :  .    ::::::::. :::::::::::::::.:::::::::::
NP_005 SGGSGTKLPKKATKTAPPALPTGYDSEEEEESRPMSYDEKRQLSLDINKLPGEKLGRVVH
       610       620       630       640       650       660       

       600       610       620       630       640       650       
pF1KSD IIQSREPSLRDSNPDEIEIDFETLKPTTLRELERYVKSCLQKKQRKPFSASGKKQAAKSK
       :::.::::::::::.:::::::::::.::::::::: :::.:: :::..   :: ..:.:
NP_005 IIQAREPSLRDSNPEEIEIDFETLKPSTLRELERYVLSCLRKKPRKPYTI--KKPVGKTK
       670       680       690       700       710         720     

       660       670       680         690         700        710  
pF1KSD EELAQEKKKELEKRLQDVSGQLSSSKKPARK--EKP--GSAPSGGPSRLS-SSSSSESGS
       :::: :::.:::::::::::::.:.::: .:  ::   .:: . . :::: :::::.:.:
NP_005 EELALEKKRELEKRLQDVSGQLNSTKKPPKKANEKTESSSAQQVAVSRLSASSSSSDSSS
         730       740       750       760       770       780     

            720        
pF1KSD SSSSGSSSDSSDSE  
       ::::.::::.:     
NP_005 SSSSSSSSDTSDSDSG
         790       800 

>>NP_001186384 (OMIM: 601540) bromodomain-containing pro  (836 aa)
 initn: 2880 init1: 940 opt: 1971  Z-score: 899.8  bits: 177.3 E(85289): 2.2e-43
Smith-Waterman score: 2760; 60.7% identity (75.4% similar) in 756 aa overlap (10-688:49-791)

                                    10         20        30        
pF1KSD                      MSTATTVAPAGIPATP-GPVNPPPPEVSNPSKPGRKTNQ
                                     :..::    :.::::::::::.:::: :::
NP_001 LLGLGPEAAAPGKRIRKPSLLYEGFESPTMASVPALQLTPANPPPPEVSNPKKPGRVTNQ
       20        30        40        50        60        70        

       40        50        60        70        80        90        
pF1KSD LQYMQNVVVKTLWKHQFAWPFYQPVDAIKLNLPDYHKIIKNPMDMGTIKKRLENNYYWSA
       :::...::.:.:::::::::: :::::.::.:::::::::.::::::::.::::::::.:
NP_001 LQYLHKVVMKALWKHQFAWPFRQPVDAVKLGLPDYHKIIKQPMDMGTIKRRLENNYYWAA
       80        90       100       110       120       130        

      100       110       120       130       140       150        
pF1KSD SECMQDFNTMFTNCYIYNKPTDDIVLMAQALEKIFLQKVAQMPQEEVELLPPAPKGKGRK
       :::::::::::::::::::::::::::::.::::::::::.::::: ::.   ::.. .:
NP_001 SECMQDFNTMFTNCYIYNKPTDDIVLMAQTLEKIFLQKVASMPQEEQELVVTIPKNSHKK
      140       150       160       170       180       190        

      160           170       180       190       200       210    
pF1KSD PAAGAQSAGT----QQVAAVSSVSPATPFQSVPPTVSQTPVIAATPVPTITANVTSVPVP
        :  :   :.    .:: ::::::  : . . :: .  :  .   : :.    : : :. 
NP_001 GAKLAALQGSVTSAHQVPAVSSVSH-TALYTPPPEIPTT--VLNIPHPS----VISSPLL
      200       210       220        230         240           250 

          220       230       240       250       260        270   
pF1KSD PAAAPPPPATPIVPVVPPTPPVVKKKGVKRKADTTTPTTSAITASRSESPPPLS-DPKQA
        .     :    : ..::. :..::::::::::::::: .:: :  : . :: : .:: :
NP_001 KSLHSAGPPLLAVTAAPPAQPLAKKKGVKRKADTTTPTPTAILAPGSPASPPGSLEPKAA
             260       270       280       290       300       310 

           280       290       300       310       320       330   
pF1KSD KVVARRESGGRPIKPPKKDLEDGEVPQHAGKKGKLSEHLRYCDSILREMLSKKHAAYAWP
       ..   :. .:::::::.::: :..  ....:::::::.:..:..::.:.:::::::::::
NP_001 RLPPMRRESGRPIKPPRKDLPDSQQQHQSSKKGKLSEQLKHCNGILKELLSKKHAAYAWP
             320       330       340       350       360       370 

           340       350       360       370       380       390   
pF1KSD FYKPVDAEALELHDYHDIIKHPMDLSTVKRKMDGREYPDAQGFAADVRLMFSNCYKYNPP
       ::::::: :: :::::::::::::::::::::..:.: ::: ::::::::::::::::::
NP_001 FYKPVDASALGLHDYHDIIKHPMDLSTVKRKMENRDYRDAQEFAADVRLMFSNCYKYNPP
             380       390       400       410       420       430 

           400       410       420       430         440       450 
pF1KSD DHEVVAMARKLQDVFEMRFAKMPDEPVEAPALPAPAA--PMVSKGAESSRSSEESSSDSG
       ::.:::::::::::::.:.:::::::.:   ::. .:  : ..:.. :  :::::::.:.
NP_001 DHDVVAMARKLQDVFEFRYAKMPDEPLEPGPLPVSTAMPPGLAKSS-SESSSEESSSESS
             440       450       460       470        480       490

                               460       470       480       490   
pF1KSD S------------------SDSEEERATRLAELQEQLKAVHEQLAALSQAPVNKPKKKKE
       :                  :::::::: :::::::::.:::::::::::.:..:::.:.:
NP_001 SEEEEEEDEEDEEEEESESSDSEEERAHRLAELQEQLRAVHEQLAALSQGPISKPKRKRE
              500       510       520       530       540       550

           500       510       520        530                      
pF1KSD KKEKEKKKKDKEKEKEKHKVKAEEEKKAKVAP-PAKQAQQKKA----------------P
       ::::.::.:    ::.. .. :.:. :.  :: : .  ..:::                :
NP_001 KKEKKKKRK---AEKHRGRAGADEDDKGPRAPRPPQPKKSKKASGSGGGSAALGPSGFGP
                 560       570       580       590       600       

        540       550                                 560          
pF1KSD AKKANSTTTAGRQLKKGG--------------------------KQASAS--------YD
       .  ...   :: : .  :                          :.:. .        ::
NP_001 SGGSGTKLQAGVQWRDLGLLQPPLLGFKRFSCLSLPSSQDYRLPKKATKTAPPALPTGYD
       610       620       630       640       650       660       

            570       580       590       600       610       620  
pF1KSD SEEEEEGLPMSYDEKRQLSLDINRLPGEKLGRVVHIIQSREPSLRDSNPDEIEIDFETLK
       ::::::. :::::::::::::::.::::::::::::::.::::::::::.::::::::::
NP_001 SEEEEESRPMSYDEKRQLSLDINKLPGEKLGRVVHIIQAREPSLRDSNPEEIEIDFETLK
       670       680       690       700       710       720       

            630       640       650       660       670       680  
pF1KSD PTTLRELERYVKSCLQKKQRKPFSASGKKQAAKSKEELAQEKKKELEKRLQDVSGQLSSS
       :.::::::::: :::.:: :::..   :: ..:.::::: :::.:::::::::::::.:.
NP_001 PSTLRELERYVLSCLRKKPRKPYTI--KKPVGKTKEELALEKKRELEKRLQDVSGQLNST
       730       740       750         760       770       780     

            690       700       710       720             
pF1KSD KKPARKEKPGSAPSGGPSRLSSSSSSESGSSSSSGSSSDSSDSE       
       ::: .:                                             
NP_001 KKPPKKANEKTESSSAQQVAVSRLSASSSSSDSSSSSSSSSSSDTSDSDSG
         790       800       810       820       830      

>>NP_001317313 (OMIM: 608749) bromodomain-containing pro  (794 aa)
 initn: 2726 init1: 939 opt: 1742  Z-score: 798.0  bits: 158.4 E(85289): 1e-37
Smith-Waterman score: 2526; 58.0% identity (74.8% similar) in 734 aa overlap (1-700:26-733)

                                        10        20        30     
pF1KSD                          MSTATTVAPAGIPATPGPVNPPPPEVSNPSKPGRK
                                :::. . :    ::. . .::::::.:::.:: :.
NP_001 MSAESGPGTRLRNLPVMGDGLETSQMSTTQAQAQPQ-PANAASTNPPPPETSNPNKPKRQ
               10        20        30         40        50         

          40        50        60        70        80        90     
pF1KSD TNQLQYMQNVVVKTLWKHQFAWPFYQPVDAIKLNLPDYHKIIKNPMDMGTIKKRLENNYY
       ::::::.  ::.:::::::::::: :::::.:::::::.::::.::::::::::::::::
NP_001 TNQLQYLLRVVLKTLWKHQFAWPFQQPVDAVKLNLPDYYKIIKTPMDMGTIKKRLENNYY
      60        70        80        90       100       110         

         100       110       120       130       140       150     
pF1KSD WSASECMQDFNTMFTNCYIYNKPTDDIVLMAQALEKIFLQKVAQMPQEEVELLPPAPKGK
       :.:.::.:::::::::::::::: :::::::.::::.::::. ..: ::.:..    ::.
NP_001 WNAQECIQDFNTMFTNCYIYNKPGDDIVLMAEALEKLFLQKINELPTEETEIMIVQAKGR
     120       130       140       150       160       170         

          160       170         180        190                200  
pF1KSD GR-KPAAGAQSAGTQQVAAVSSVS--PATPF-QSVPPTVSQTP---------VIAATPVP
       :: .  .:. . :.. :  ....:  : :   :  :: :. ::         .:. ::: 
NP_001 GRGRKETGTAKPGVSTVPNTTQASTPPQTQTPQPNPPPVQATPHPFPAVTPDLIVQTPVM
     180       190       200       210       220       230         

               210       220            230        240       250   
pF1KSD TITANV---TSVPVPPAAAPPP-PATPIV----PVVPPTP-PVVKKKGVKRKADTTTPTT
       :..      :  ::::   ::: ::   :    :..  :: ::  :::::::::::::: 
NP_001 TVVPPQPLQTPPPVPPQPQPPPAPAPQPVQSHPPIIAATPQPVKTKKGVKRKADTTTPT-
     240       250       260       270       280       290         

           260        270       280       290       300         310
pF1KSD SAITASRSESPPPLS-DPKQAKVVARRESGGRPIKPPKKDLEDGEVPQHAG--KKGKLSE
          : .  . :: :  .:: .:.  ::::. ::.::::::. :..  :: .  :..:.::
NP_001 ---TIDPIHEPPSLPPEPKTTKLGQRRESS-RPVKPPKKDVPDSQ--QHPAPEKSSKVSE
         300       310       320        330         340       350  

              320       330       340       350       360       370
pF1KSD HLRYCDSILREMLSKKHAAYAWPFYKPVDAEALELHDYHDIIKHPMDLSTVKRKMDGREY
       .:. :..::.::..:::::::::::::::.::: :::: ::::::::.::.: :...:::
NP_001 QLKCCSGILKEMFAKKHAAYAWPFYKPVDVEALGLHDYCDIIKHPMDMSTIKSKLEAREY
            360       370       380       390       400       410  

              380       390       400       410             420    
pF1KSD PDAQGFAADVRLMFSNCYKYNPPDHEVVAMARKLQDVFEMRFAKMPDEP------VEAPA
        ::: :.::::::::::::::::::::::::::::::::::::::::::      : .::
NP_001 RDAQEFGADVRLMFSNCYKYNPPDHEVVAMARKLQDVFEMRFAKMPDEPEEPVVAVSSPA
            420       430       440       450       460       470  

          430       440       450       460       470       480    
pF1KSD LPAPAAPMVSKGAESSRSSEESSSDSGSSDSEEERATRLAELQEQLKAVHEQLAALSQAP
       .: :.  ..  .. .: :.  :.:::...::::::: :::::::::::::::::::::  
NP_001 VPPPTKVVAPPSSSDSSSDSSSDSDSSTDDSEEERAQRLAELQEQLKAVHEQLAALSQPQ
            480       490       500       510       520       530  

          490       500       510       520       530       540    
pF1KSD VNKPKKKKEKKEKEKKKKDKEKEKEKHKVKAEEEKKAKVAPPAKQAQQKKAPAKKANSTT
        ::::::    ::.::.: :::.:.:..:. ....:::  :: :    ::  ....: . 
NP_001 QNKPKKK----EKDKKEKKKEKHKRKEEVEENKKSKAKEPPPKKT---KKNNSSNSNVSK
                540       550       560       570          580     

          550       560       570       580       590       600    
pF1KSD TAGRQLKKGGKQASASYDSEEEEEGLPMSYDEKRQLSLDINRLPGEKLGRVVHIIQSREP
            .:   ..   .:.::::..  ::::.::::::::::.::::::::::::::::::
NP_001 KEPAPMK---SKPPPTYESEEEDKCKPMSYEEKRQLSLDINKLPGEKLGRVVHIIQSREP
         590          600       610       620       630       640  

          610       620       630       640       650       660    
pF1KSD SLRDSNPDEIEIDFETLKPTTLRELERYVKSCLQKKQRKPFSASGKKQAAKSKEELAQEK
       ::..:::::::::::::::.::::::::: :::.:: :::       :: :     .. :
NP_001 SLKNSNPDEIEIDFETLKPSTLRELERYVTSCLRKK-RKP-------QAEKVDVIAGSSK
            650       660       670        680              690    

          670       680       690          700       710       720 
pF1KSD KKELEKRLQDVSGQLSSSKKPARKEK---PGSAPSGGPSRLSSSSSSESGSSSSSGSSSD
        : . .  .. :.. ::: .   .      :.  : :::                     
NP_001 MKGFSSSESESSSESSSSDSEDSETAFCTSGDFVSPGPSPYHSHVQCGRFREMLRWFLVD
          700       710       720       730       740       750    

                                               
pF1KSD SSDSE                                   
                                               
NP_001 VEQTAAGQPHRQSAAGPAITWAPAIAYPSPECARCCVGCS
          760       770       780       790    




726 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Wed Nov  2 23:36:04 2016 done: Wed Nov  2 23:36:05 2016
 Total Scan time: 11.200 Total Display time:  0.180

Function used was FASTA [36.3.4 Apr, 2011]
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