Result of FASTA (omim) for pF1KSDA0023
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KSDA0023, 2093 aa
  1>>>pF1KSDA0023 2093 - 2093 aa - 2093 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 17.0276+/-0.000505; mu= -30.8714+/- 0.031
 mean_var=716.5798+/-151.098, 0's: 0 Z-trim(121.5): 127  B-trim: 0 in 0/59
 Lambda= 0.047912
 statistics sampled from 38157 (38299) to 38157 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.726), E-opt: 0.2 (0.449), width:  16
 Scan time: 19.780

The best scores are:                                      opt bits E(85289)
XP_006717355 (OMIM: 114350,613065) PREDICTED: nucl (2120) 8046 573.3 9.6e-162
XP_011517355 (OMIM: 114350,613065) PREDICTED: nucl (2120) 8017 571.3 3.9e-161
XP_005272273 (OMIM: 114350,613065) PREDICTED: nucl (2132) 5919 426.3 1.8e-117
NP_005076 (OMIM: 114350,613065) nuclear pore compl (2090) 5917 426.2 1.9e-117
NP_001305253 (OMIM: 114350,613065) nuclear pore co (2080) 5887 424.1  8e-117
XP_016870656 (OMIM: 114350,613065) PREDICTED: nucl (2119) 5878 423.5 1.2e-116
XP_005272276 (OMIM: 114350,613065) PREDICTED: nucl (2036) 5853 421.7  4e-116
NP_001305254 (OMIM: 114350,613065) nuclear pore co ( 916) 5306 383.7  5e-105
XP_005272275 (OMIM: 114350,613065) PREDICTED: nucl (2083) 5189 375.9 2.7e-102
XP_011517357 (OMIM: 114350,613065) PREDICTED: nucl (1908) 4833 351.2 6.3e-95
NP_002448 (OMIM: 158370) mucin-2 precursor [Homo s (5289)  547 55.2 2.2e-05
XP_016868343 (OMIM: 615753) PREDICTED: nuclear env ( 984)  513 52.4 2.9e-05
XP_006716259 (OMIM: 615753) PREDICTED: nuclear env ( 984)  513 52.4 2.9e-05
NP_742017 (OMIM: 615753) nuclear envelope pore mem ( 984)  513 52.4 2.9e-05
XP_016868342 (OMIM: 615753) PREDICTED: nuclear env ( 984)  513 52.4 2.9e-05
XP_005250783 (OMIM: 615753) PREDICTED: nuclear env (1249)  513 52.5 3.5e-05
NP_001244119 (OMIM: 615753) nuclear envelope pore  ( 999)  504 51.8 4.5e-05
NP_001291288 (OMIM: 158373) mucin-5AC precursor [H (5654)  526 53.8 6.4e-05
XP_011515032 (OMIM: 615753) PREDICTED: nuclear env (1153)  473 49.7 0.00022
NP_001157934 (OMIM: 604609) mucin-12 precursor [Ho (5335)  489 51.2 0.00036
NP_001014364 (OMIM: 616284) filaggrin-2 [Homo sapi (2391)  474 50.0 0.00038
NP_001035194 (OMIM: 608424) mucin-17 precursor [Ho (4493)  467 49.7  0.0009
XP_005250784 (OMIM: 615753) PREDICTED: nuclear env (1190)  409 45.3  0.0049
NP_060876 (OMIM: 158372) mucin-4 isoform a precurs (5412)  434 47.4  0.0051
NP_005952 (OMIM: 158374) mucin-6 precursor [Homo s (2439)  409 45.5  0.0088
XP_011514552 (OMIM: 158371) PREDICTED: mucin-3A is (3076)  412 45.8  0.0092
XP_016867720 (OMIM: 158371) PREDICTED: mucin-3A is (3143)  412 45.8  0.0093
XP_011514551 (OMIM: 158371) PREDICTED: mucin-3A is (3245)  412 45.8  0.0096
XP_011514549 (OMIM: 158371) PREDICTED: mucin-3A is (3296)  412 45.8  0.0097
XP_011514548 (OMIM: 158371) PREDICTED: mucin-3A is (3313)  412 45.8  0.0098
NP_005951 (OMIM: 158371) mucin-3A precursor [Homo  (3323)  412 45.8  0.0098


>>XP_006717355 (OMIM: 114350,613065) PREDICTED: nuclear   (2120 aa)
 initn: 7624 init1: 7362 opt: 8046  Z-score: 3024.8  bits: 573.3 E(85289): 9.6e-162
Smith-Waterman score: 12917; 98.1% identity (98.5% similar) in 2051 aa overlap (1-2041:42-2091)

                                             10        20        30
pF1KSD                               MGDEMDAMIPEREMKDFQFRALKKVRIFDS
                                     ::::::::::::::::::::::::::::::
XP_006 GRKFAVERPGFRGQGRGRQRWLLRHTEGGAMGDEMDAMIPEREMKDFQFRALKKVRIFDS
              20        30        40        50        60        70 

               40        50        60        70        80        90
pF1KSD PEELPKERSSLLAVSNKYGLVFAGGASGLQIFPTKNLLIQNKPGDDPNKIVDKVQGLLVP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 PEELPKERSSLLAVSNKYGLVFAGGASGLQIFPTKNLLIQNKPGDDPNKIVDKVQGLLVP
              80        90       100       110       120       130 

              100       110       120       130       140       150
pF1KSD MKFPIHHLALSCDNLTLSACMMSSEYGSIIAFFDVRTFSNEAKQQKRPFAYHKLLKDAGG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 MKFPIHHLALSCDNLTLSACMMSSEYGSIIAFFDVRTFSNEAKQQKRPFAYHKLLKDAGG
             140       150       160       170       180       190 

              160       170       180       190       200       210
pF1KSD MVIDMKWNPTVPSMVAVCLADGSIAVLQVTETVKVCATLPSTVAVTSVCWSPKGKQLAVG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 MVIDMKWNPTVPSMVAVCLADGSIAVLQVTETVKVCATLPSTVAVTSVCWSPKGKQLAVG
             200       210       220       230       240       250 

              220       230       240       250       260       270
pF1KSD KQNGTVVQYLPTLQEKKVIPCPPFYESDHPVRVLDVLWIGTYVFAIVYAAADGTLETSPD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 KQNGTVVQYLPTLQEKKVIPCPPFYESDHPVRVLDVLWIGTYVFAIVYAAADGTLETSPD
             260       270       280       290       300       310 

              280       290       300       310       320       330
pF1KSD VVMALLPKKEEKHPEIFVNFMEPCYGSCTERQHHYYLSYIEEWDLVLAASAASTEVSILA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 VVMALLPKKEEKHPEIFVNFMEPCYGSCTERQHHYYLSYIEEWDLVLAASAASTEVSILA
             320       330       340       350       360       370 

              340       350       360       370       380       390
pF1KSD RQSDQINWESWLLEDSSRAELPVTDKSDDSLPMGVVVDYTNQVEITISDEKTLPPAPVLM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 RQSDQINWESWLLEDSSRAELPVTDKSDDSLPMGVVVDYTNQVEITISDEKTLPPAPVLM
             380       390       400       410       420       430 

              400       410       420       430       440       450
pF1KSD LLSTDGVLCPFYMINQNPGVKSLIKTPERLSLEGERQPKSPGSTPTTPTSSQAPQKLDAS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LLSTDGVLCPFYMINQNPGVKSLIKTPERLSLEGERQPKSPGSTPTTPTSSQAPQKLDAS
             440       450       460       470       480       490 

              460       470       480       490       500       510
pF1KSD AAAAPASLPPSSPAAPIATFSLLPAGGAPTVFSFGSSSLKSSATVTGEPPSYSSGSDSSK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 AAAAPASLPPSSPAAPIATFSLLPAGGAPTVFSFGSSSLKSSATVTGEPPSYSSGSDSSK
             500       510       520       530       540       550 

              520       530       540       550       560       570
pF1KSD AAPGPGPSTFSFVPPSKASLAPTPAASPVAPSAASFSFGSSGFKPTLESTPVPSVSAPNI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 AAPGPGPSTFSFVPPSKASLAPTPAASPVAPSAASFSFGSSGFKPTLESTPVPSVSAPNI
             560       570       580       590       600       610 

              580       590       600       610       620       630
pF1KSD AMKPSFPPSTSAVKVNLSENSSQSAPPMSPFSSASKPAASGPLSHPTPLSAPPSSVPLKS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 AMKPSFPPSTSAVKVNLSENSSQSAPPMSPFSSASKPAASGPLSHPTPLSAPPSSVPLKS
             620       630       640       650       660       670 

              640       650       660       670       680       690
pF1KSD SVLPSPSGRSAQGSSSPVPSMVQKSPRITPPAAKPGSPQAKSLQPAVAEKQGHQWKDSDP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 SVLPSPSGRSAQGSSSPVPSMVQKSPRITPPAAKPGSPQAKSLQPAVAEKQGHQWKDSDP
             680       690       700       710       720       730 

              700       710       720       730       740       750
pF1KSD VMAGIGEEIAHFQKELEELKARTSKACFQVGTSEEMKMLRTESDDLHTFLLEIKETTESL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 VMAGIGEEIAHFQKELEELKARTSKACFQVGTSEEMKMLRTESDDLHTFLLEIKETTESL
             740       750       760       770       780       790 

              760       770       780       790       800       810
pF1KSD HGDISSLKTTLLEGFAGVEEAREQNERNRDSGYLHLLYKRPLDPKSEAQLQEIRRLHQYV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 HGDISSLKTTLLEGFAGVEEAREQNERNRDSGYLHLLYKRPLDPKSEAQLQEIRRLHQYV
             800       810       820       830       840       850 

              820       830       840       850       860       870
pF1KSD KFAVQDVNDVLDLEWDQHLEQKKKQRHLLVPERETLFNTLANNREIINQQRKRLNHLVDS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 KFAVQDVNDVLDLEWDQHLEQKKKQRHLLVPERETLFNTLANNREIINQQRKRLNHLVDS
             860       870       880       890       900       910 

              880       890       900       910       920       930
pF1KSD LQQLRLYKQTSLWSLSSAVPSQSSIHSFDSDLESLCNALLKTTIESHTKSLPKVPAKLSP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LQQLRLYKQTSLWSLSSAVPSQSSIHSFDSDLESLCNALLKTTIESHTKSLPKVPAKLSP
             920       930       940       950       960       970 

              940       950       960       970       980       990
pF1KSD MKQAQLRNFLAKRKTPPVRSTAPASLSRSAFLSQRYYEDLDEVSSTSSVSQSLESEDART
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 MKQAQLRNFLAKRKTPPVRSTAPASLSRSAFLSQRYYEDLDEVSSTSSVSQSLESEDART
             980       990      1000      1010      1020      1030 

             1000      1010      1020      1030      1040      1050
pF1KSD SCKDDEAVVQAPRHAPVVRTPSIQPSLLPHAAPFAKSHLVHGSSPGVMGTSVATSASKII
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 SCKDDEAVVQAPRHAPVVRTPSIQPSLLPHAAPFAKSHLVHGSSPGVMGTSVATSASKII
            1040      1050      1060      1070      1080      1090 

             1060      1070      1080      1090      1100      1110
pF1KSD PQGADSTMLATKTVKHGAPSPSHPISAPQAAAAAALRRQMASQAPAVNTLTESTLKNVPQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 PQGADSTMLATKTVKHGAPSPSHPISAPQAAAAAALRRQMASQAPAVNTLTESTLKNVPQ
            1100      1110      1120      1130      1140      1150 

             1120                1130      1140      1150      1160
pF1KSD VVNVQELKNNPATPSTA----------KTPHPVLTPVAANQAKQGSLINSLKPSGPTPAS
       :::::::::::::::::          :::::::::::::::::::::::::::::::::
XP_006 VVNVQELKNNPATPSTAMGSSVPYSTAKTPHPVLTPVAANQAKQGSLINSLKPSGPTPAS
            1160      1170      1180      1190      1200      1210 

             1170      1180      1190      1200      1210      1220
pF1KSD GQLSSGDKASGTAKIETAVTSTPSASGQFSKPFSFSPSGTGFNFGIITPTPSSNFTAAQG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 GQLSSGDKASGTAKIETAVTSTPSASGQFSKPFSFSPSGTGFNFGIITPTPSSNFTAAQG
            1220      1230      1240      1250      1260      1270 

             1230      1240      1250      1260      1270      1280
pF1KSD ATPSTKESSQPDAFSSGGGSKPSYEAIPESSPPSGITSASNTTPGEPAASSSRPVAPSGT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 ATPSTKESSQPDAFSSGGGSKPSYEAIPESSPPSGITSASNTTPGEPAASSSRPVAPSGT
            1280      1290      1300      1310      1320      1330 

             1290      1300      1310      1320      1330      1340
pF1KSD ALSTTSSKLETPPSKLGELLFPSSLAGETLGSFSGLRVGQADDSTKPTNKASSTSLTSTQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 ALSTTSSKLETPPSKLGELLFPSSLAGETLGSFSGLRVGQADDSTKPTNKASSTSLTSTQ
            1340      1350      1360      1370      1380      1390 

             1350      1360      1370      1380      1390      1400
pF1KSD PTKTSGVPSGFNFTAPPVLGKHTEPPVTSSATTTSVAPPAATSTSSTAVFGSLPVTSAGS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 PTKTSGVPSGFNFTAPPVLGKHTEPPVTSSATTTSVAPPAATSTSSTAVFGSLPVTSAGS
            1400      1410      1420      1430      1440      1450 

             1410      1420      1430      1440      1450      1460
pF1KSD SGVISFGGTSLSAGKTSFSFGSQQTNSTVPPSAPPPTTAATPLPTSFPTLSFGSLLSSAT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 SGVISFGGTSLSAGKTSFSFGSQQTNSTVPPSAPPPTTAATPLPTSFPTLSFGSLLSSAT
            1460      1470      1480      1490      1500      1510 

             1470      1480      1490      1500      1510      1520
pF1KSD TPSLPMSAGRSTEEATSSALPEKPGDSEVSASAASLLEEQQSAQLPQAPPQTSDSVKKEP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 TPSLPMSAGRSTEEATSSALPEKPGDSEVSASAASLLEEQQSAQLPQAPPQTSDSVKKEP
            1520      1530      1540      1550      1560      1570 

             1530      1540      1550      1560      1570      1580
pF1KSD VLAQPAVSNSGTAASSTSLVALSAEATPATTGVPDARTEAVPPASSFSVPGQTAVTAAAI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 VLAQPAVSNSGTAASSTSLVALSAEATPATTGVPDARTEAVPPASSFSVPGQTAVTAAAI
            1580      1590      1600      1610      1620      1630 

             1590      1600      1610      1620      1630      1640
pF1KSD SSAGPVAVETSSTPIASSTTSIVAPGPSAEAAAFGTVTSGSSVFAQPPAASSSSAFNQLT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 SSAGPVAVETSSTPIASSTTSIVAPGPSAEAAAFGTVTSGSSVFAQPPAASSSSAFNQLT
            1640      1650      1660      1670      1680      1690 

             1650      1660      1670      1680      1690      1700
pF1KSD NNTATAPSATPVFGQVAASTAPSLFGQQTGSTASTAAATPQVSSSGFSSPAFGTTAPGVF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 NNTATAPSATPVFGQVAASTAPSLFGQQTGSTASTAAATPQVSSSGFSSPAFGTTAPGVF
            1700      1710      1720      1730      1740      1750 

             1710      1720      1730      1740      1750      1760
pF1KSD GQTTFGQASVFGQSASSAASVFSFSQPGFSSVPAFGQPASSTPTSTSGSVFGAASSTSSS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 GQTTFGQASVFGQSASSAASVFSFSQPGFSSVPAFGQPASSTPTSTSGSVFGAASSTSSS
            1760      1770      1780      1790      1800      1810 

             1770      1780      1790      1800      1810      1820
pF1KSD SSFSFGQSSPNTGGGLFGQSNAPAFGQSPGFGQGGSVFGGTSAATTTAATSGFSFCQASG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 SSFSFGQSSPNTGGGLFGQSNAPAFGQSPGFGQGGSVFGGTSAATTTAATSGFSFCQASG
            1820      1830      1840      1850      1860      1870 

             1830      1840      1850      1860      1870      1880
pF1KSD FGSSNTGSVFGQAASTGGIVFGQQSSSSSGSVFGSGNTGRGGGFFSGLGGKPSQDAANKN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 FGSSNTGSVFGQAASTGGIVFGQQSSSSSGSVFGSGNTGRGGGFFSGLGGKPSQDAANKN
            1880      1890      1900      1910      1920      1930 

             1890      1900      1910      1920      1930      1940
pF1KSD PFSSASGGFGSTATSNTSNLFGNSGAKTFGGFASSSFGEQKPTGTFSSGGGSVASQGFGF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 PFSSASGGFGSTATSNTSNLFGNSGAKTFGGFASSSFGEQKPTGTFSSGGGSVASQGFGF
            1940      1950      1960      1970      1980      1990 

             1950      1960      1970      1980      1990      2000
pF1KSD SSPNKTGGFGAAPVFGSPPTFGGSPGFGGVPAFGSAPAFTSPLGSTGGKVFGEGTAAASA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 SSPNKTGGFGAAPVFGSPPTFGGSPGFGGVPAFGSAPAFTSPLGSTGGKVFGEGTAAASA
            2000      2010      2020      2030      2040      2050 

             2010      2020      2030      2040      2050      2060
pF1KSD GGFGSLAMSLSPTLKGRLLLMRPKAGGGREQAAPGRKSNESRSLGHLCMERALTSPLKVW
       :::: .. : . :  : :  .   . :.  : . :  .. :                   
XP_006 GGFG-FGSSSNTTSFGTLASQNAPTFGSLSQQTSGFGTQSSGFSGFGSGTGGFSFGSNNS
             2060      2070      2080      2090      2100      2110

             2070      2080      2090   
pF1KSD EQQQHHILRHARESECPHFRITVPTDFWFWDPE
                                        
XP_006 SVQGFGGWRS                       
             2120                       

>>XP_011517355 (OMIM: 114350,613065) PREDICTED: nuclear   (2120 aa)
 initn: 7304 init1: 7042 opt: 8017  Z-score: 3013.9  bits: 571.3 E(85289): 3.9e-161
Smith-Waterman score: 12888; 98.0% identity (98.4% similar) in 2052 aa overlap (1-2041:42-2091)

                                             10        20        30
pF1KSD                               MGDEMDAMIPEREMKDFQFRALKKVRIFDS
                                     ::::::::::::::::::::::::::::::
XP_011 GRKFAVERPGFRGQGRGRQRWLLRHTEGGAMGDEMDAMIPEREMKDFQFRALKKVRIFDS
              20        30        40        50        60        70 

               40        50        60        70        80        90
pF1KSD PEELPKERSSLLAVSNKYGLVFAGGASGLQIFPTKNLLIQNKPGDDPNKIVDKVQGLLVP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PEELPKERSSLLAVSNKYGLVFAGGASGLQIFPTKNLLIQNKPGDDPNKIVDKVQGLLVP
              80        90       100       110       120       130 

              100       110       120       130       140       150
pF1KSD MKFPIHHLALSCDNLTLSACMMSSEYGSIIAFFDVRTFSNEAKQQKRPFAYHKLLKDAGG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MKFPIHHLALSCDNLTLSACMMSSEYGSIIAFFDVRTFSNEAKQQKRPFAYHKLLKDAGG
             140       150       160       170       180       190 

              160       170       180       190       200       210
pF1KSD MVIDMKWNPTVPSMVAVCLADGSIAVLQVTETVKVCATLPSTVAVTSVCWSPKGKQLAVG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MVIDMKWNPTVPSMVAVCLADGSIAVLQVTETVKVCATLPSTVAVTSVCWSPKGKQLAVG
             200       210       220       230       240       250 

              220       230       240       250       260       270
pF1KSD KQNGTVVQYLPTLQEKKVIPCPPFYESDHPVRVLDVLWIGTYVFAIVYAAADGTLETSPD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KQNGTVVQYLPTLQEKKVIPCPPFYESDHPVRVLDVLWIGTYVFAIVYAAADGTLETSPD
             260       270       280       290       300       310 

              280       290       300       310       320       330
pF1KSD VVMALLPKKEEKHPEIFVNFMEPCYGSCTERQHHYYLSYIEEWDLVLAASAASTEVSILA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VVMALLPKKEEKHPEIFVNFMEPCYGSCTERQHHYYLSYIEEWDLVLAASAASTEVSILA
             320       330       340       350       360       370 

              340       350       360       370       380       390
pF1KSD RQSDQINWESWLLEDSSRAELPVTDKSDDSLPMGVVVDYTNQVEITISDEKTLPPAPVLM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RQSDQINWESWLLEDSSRAELPVTDKSDDSLPMGVVVDYTNQVEITISDEKTLPPAPVLM
             380       390       400       410       420       430 

              400       410       420       430       440       450
pF1KSD LLSTDGVLCPFYMINQNPGVKSLIKTPERLSLEGERQPKSPGSTPTTPTSSQAPQKLDAS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LLSTDGVLCPFYMINQNPGVKSLIKTPERLSLEGERQPKSPGSTPTTPTSSQAPQKLDAS
             440       450       460       470       480       490 

              460       470       480       490       500       510
pF1KSD AAAAPASLPPSSPAAPIATFSLLPAGGAPTVFSFGSSSLKSSATVTGEPPSYSSGSDSSK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AAAAPASLPPSSPAAPIATFSLLPAGGAPTVFSFGSSSLKSSATVTGEPPSYSSGSDSSK
             500       510       520       530       540       550 

              520       530       540       550       560       570
pF1KSD AAPGPGPSTFSFVPPSKASLAPTPAASPVAPSAASFSFGSSGFKPTLESTPVPSVSAPNI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AAPGPGPSTFSFVPPSKASLAPTPAASPVAPSAASFSFGSSGFKPTLESTPVPSVSAPNI
             560       570       580       590       600       610 

              580       590       600       610       620       630
pF1KSD AMKPSFPPSTSAVKVNLSENSSQSAPPMSPFSSASKPAASGPLSHPTPLSAPPSSVPLKS
       ::::::::::::::::::::: ::::::::::::::::::::::::::::::::::::::
XP_011 AMKPSFPPSTSAVKVNLSENS-QSAPPMSPFSSASKPAASGPLSHPTPLSAPPSSVPLKS
             620       630        640       650       660       670

               640       650       660       670       680         
pF1KSD SVLPSPS-GRSAQGSSSPVPSMVQKSPRITPPAAKPGSPQAKSLQPAVAEKQGHQWKDSD
       ::::::: ::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SVLPSPSAGRSAQGSSSPVPSMVQKSPRITPPAAKPGSPQAKSLQPAVAEKQGHQWKDSD
              680       690       700       710       720       730

     690       700       710       720       730       740         
pF1KSD PVMAGIGEEIAHFQKELEELKARTSKACFQVGTSEEMKMLRTESDDLHTFLLEIKETTES
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PVMAGIGEEIAHFQKELEELKARTSKACFQVGTSEEMKMLRTESDDLHTFLLEIKETTES
              740       750       760       770       780       790

     750       760       770       780       790       800         
pF1KSD LHGDISSLKTTLLEGFAGVEEAREQNERNRDSGYLHLLYKRPLDPKSEAQLQEIRRLHQY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LHGDISSLKTTLLEGFAGVEEAREQNERNRDSGYLHLLYKRPLDPKSEAQLQEIRRLHQY
              800       810       820       830       840       850

     810       820       830       840       850       860         
pF1KSD VKFAVQDVNDVLDLEWDQHLEQKKKQRHLLVPERETLFNTLANNREIINQQRKRLNHLVD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VKFAVQDVNDVLDLEWDQHLEQKKKQRHLLVPERETLFNTLANNREIINQQRKRLNHLVD
              860       870       880       890       900       910

     870       880       890       900       910       920         
pF1KSD SLQQLRLYKQTSLWSLSSAVPSQSSIHSFDSDLESLCNALLKTTIESHTKSLPKVPAKLS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SLQQLRLYKQTSLWSLSSAVPSQSSIHSFDSDLESLCNALLKTTIESHTKSLPKVPAKLS
              920       930       940       950       960       970

     930       940       950       960       970       980         
pF1KSD PMKQAQLRNFLAKRKTPPVRSTAPASLSRSAFLSQRYYEDLDEVSSTSSVSQSLESEDAR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PMKQAQLRNFLAKRKTPPVRSTAPASLSRSAFLSQRYYEDLDEVSSTSSVSQSLESEDAR
              980       990      1000      1010      1020      1030

     990      1000      1010      1020      1030      1040         
pF1KSD TSCKDDEAVVQAPRHAPVVRTPSIQPSLLPHAAPFAKSHLVHGSSPGVMGTSVATSASKI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TSCKDDEAVVQAPRHAPVVRTPSIQPSLLPHAAPFAKSHLVHGSSPGVMGTSVATSASKI
             1040      1050      1060      1070      1080      1090

    1050      1060      1070      1080      1090      1100         
pF1KSD IPQGADSTMLATKTVKHGAPSPSHPISAPQAAAAAALRRQMASQAPAVNTLTESTLKNVP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IPQGADSTMLATKTVKHGAPSPSHPISAPQAAAAAALRRQMASQAPAVNTLTESTLKNVP
             1100      1110      1120      1130      1140      1150

    1110      1120                1130      1140      1150         
pF1KSD QVVNVQELKNNPATPSTA----------KTPHPVLTPVAANQAKQGSLINSLKPSGPTPA
       ::::::::::::::::::          ::::::::::::::::::::::::::::::::
XP_011 QVVNVQELKNNPATPSTAMGSSVPYSTAKTPHPVLTPVAANQAKQGSLINSLKPSGPTPA
             1160      1170      1180      1190      1200      1210

    1160      1170      1180      1190      1200      1210         
pF1KSD SGQLSSGDKASGTAKIETAVTSTPSASGQFSKPFSFSPSGTGFNFGIITPTPSSNFTAAQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SGQLSSGDKASGTAKIETAVTSTPSASGQFSKPFSFSPSGTGFNFGIITPTPSSNFTAAQ
             1220      1230      1240      1250      1260      1270

    1220      1230      1240      1250      1260      1270         
pF1KSD GATPSTKESSQPDAFSSGGGSKPSYEAIPESSPPSGITSASNTTPGEPAASSSRPVAPSG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GATPSTKESSQPDAFSSGGGSKPSYEAIPESSPPSGITSASNTTPGEPAASSSRPVAPSG
             1280      1290      1300      1310      1320      1330

    1280      1290      1300      1310      1320      1330         
pF1KSD TALSTTSSKLETPPSKLGELLFPSSLAGETLGSFSGLRVGQADDSTKPTNKASSTSLTST
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TALSTTSSKLETPPSKLGELLFPSSLAGETLGSFSGLRVGQADDSTKPTNKASSTSLTST
             1340      1350      1360      1370      1380      1390

    1340      1350      1360      1370      1380      1390         
pF1KSD QPTKTSGVPSGFNFTAPPVLGKHTEPPVTSSATTTSVAPPAATSTSSTAVFGSLPVTSAG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QPTKTSGVPSGFNFTAPPVLGKHTEPPVTSSATTTSVAPPAATSTSSTAVFGSLPVTSAG
             1400      1410      1420      1430      1440      1450

    1400      1410      1420      1430      1440      1450         
pF1KSD SSGVISFGGTSLSAGKTSFSFGSQQTNSTVPPSAPPPTTAATPLPTSFPTLSFGSLLSSA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SSGVISFGGTSLSAGKTSFSFGSQQTNSTVPPSAPPPTTAATPLPTSFPTLSFGSLLSSA
             1460      1470      1480      1490      1500      1510

    1460      1470      1480      1490      1500      1510         
pF1KSD TTPSLPMSAGRSTEEATSSALPEKPGDSEVSASAASLLEEQQSAQLPQAPPQTSDSVKKE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TTPSLPMSAGRSTEEATSSALPEKPGDSEVSASAASLLEEQQSAQLPQAPPQTSDSVKKE
             1520      1530      1540      1550      1560      1570

    1520      1530      1540      1550      1560      1570         
pF1KSD PVLAQPAVSNSGTAASSTSLVALSAEATPATTGVPDARTEAVPPASSFSVPGQTAVTAAA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PVLAQPAVSNSGTAASSTSLVALSAEATPATTGVPDARTEAVPPASSFSVPGQTAVTAAA
             1580      1590      1600      1610      1620      1630

    1580      1590      1600      1610      1620      1630         
pF1KSD ISSAGPVAVETSSTPIASSTTSIVAPGPSAEAAAFGTVTSGSSVFAQPPAASSSSAFNQL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ISSAGPVAVETSSTPIASSTTSIVAPGPSAEAAAFGTVTSGSSVFAQPPAASSSSAFNQL
             1640      1650      1660      1670      1680      1690

    1640      1650      1660      1670      1680      1690         
pF1KSD TNNTATAPSATPVFGQVAASTAPSLFGQQTGSTASTAAATPQVSSSGFSSPAFGTTAPGV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TNNTATAPSATPVFGQVAASTAPSLFGQQTGSTASTAAATPQVSSSGFSSPAFGTTAPGV
             1700      1710      1720      1730      1740      1750

    1700      1710      1720      1730      1740      1750         
pF1KSD FGQTTFGQASVFGQSASSAASVFSFSQPGFSSVPAFGQPASSTPTSTSGSVFGAASSTSS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FGQTTFGQASVFGQSASSAASVFSFSQPGFSSVPAFGQPASSTPTSTSGSVFGAASSTSS
             1760      1770      1780      1790      1800      1810

    1760      1770      1780      1790      1800      1810         
pF1KSD SSSFSFGQSSPNTGGGLFGQSNAPAFGQSPGFGQGGSVFGGTSAATTTAATSGFSFCQAS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SSSFSFGQSSPNTGGGLFGQSNAPAFGQSPGFGQGGSVFGGTSAATTTAATSGFSFCQAS
             1820      1830      1840      1850      1860      1870

    1820      1830      1840      1850      1860      1870         
pF1KSD GFGSSNTGSVFGQAASTGGIVFGQQSSSSSGSVFGSGNTGRGGGFFSGLGGKPSQDAANK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GFGSSNTGSVFGQAASTGGIVFGQQSSSSSGSVFGSGNTGRGGGFFSGLGGKPSQDAANK
             1880      1890      1900      1910      1920      1930

    1880      1890      1900      1910      1920      1930         
pF1KSD NPFSSASGGFGSTATSNTSNLFGNSGAKTFGGFASSSFGEQKPTGTFSSGGGSVASQGFG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NPFSSASGGFGSTATSNTSNLFGNSGAKTFGGFASSSFGEQKPTGTFSSGGGSVASQGFG
             1940      1950      1960      1970      1980      1990

    1940      1950      1960      1970      1980      1990         
pF1KSD FSSPNKTGGFGAAPVFGSPPTFGGSPGFGGVPAFGSAPAFTSPLGSTGGKVFGEGTAAAS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FSSPNKTGGFGAAPVFGSPPTFGGSPGFGGVPAFGSAPAFTSPLGSTGGKVFGEGTAAAS
             2000      2010      2020      2030      2040      2050

    2000      2010      2020      2030      2040      2050         
pF1KSD AGGFGSLAMSLSPTLKGRLLLMRPKAGGGREQAAPGRKSNESRSLGHLCMERALTSPLKV
       ::::: .. : . :  : :  .   . :.  : . :  .. :                  
XP_011 AGGFG-FGSSSNTTSFGTLASQNAPTFGSLSQQTSGFGTQSSGFSGFGSGTGGFSFGSNN
              2060      2070      2080      2090      2100         

    2060      2070      2080      2090   
pF1KSD WEQQQHHILRHARESECPHFRITVPTDFWFWDPE
                                         
XP_011 SSVQGFGGWRS                       
    2110      2120                       

>>XP_005272273 (OMIM: 114350,613065) PREDICTED: nuclear   (2132 aa)
 initn: 9589 init1: 5595 opt: 5919  Z-score: 2230.2  bits: 426.3 E(85289): 1.8e-117
Smith-Waterman score: 12867; 97.5% identity (98.0% similar) in 2063 aa overlap (1-2041:42-2103)

                                             10        20        30
pF1KSD                               MGDEMDAMIPEREMKDFQFRALKKVRIFDS
                                     ::::::::::::::::::::::::::::::
XP_005 GRKFAVERPGFRGQGRGRQRWLLRHTEGGAMGDEMDAMIPEREMKDFQFRALKKVRIFDS
              20        30        40        50        60        70 

               40        50        60        70        80        90
pF1KSD PEELPKERSSLLAVSNKYGLVFAGGASGLQIFPTKNLLIQNKPGDDPNKIVDKVQGLLVP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PEELPKERSSLLAVSNKYGLVFAGGASGLQIFPTKNLLIQNKPGDDPNKIVDKVQGLLVP
              80        90       100       110       120       130 

              100       110       120       130       140       150
pF1KSD MKFPIHHLALSCDNLTLSACMMSSEYGSIIAFFDVRTFSNEAKQQKRPFAYHKLLKDAGG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MKFPIHHLALSCDNLTLSACMMSSEYGSIIAFFDVRTFSNEAKQQKRPFAYHKLLKDAGG
             140       150       160       170       180       190 

              160       170       180       190       200       210
pF1KSD MVIDMKWNPTVPSMVAVCLADGSIAVLQVTETVKVCATLPSTVAVTSVCWSPKGKQLAVG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MVIDMKWNPTVPSMVAVCLADGSIAVLQVTETVKVCATLPSTVAVTSVCWSPKGKQLAVG
             200       210       220       230       240       250 

              220       230       240       250       260       270
pF1KSD KQNGTVVQYLPTLQEKKVIPCPPFYESDHPVRVLDVLWIGTYVFAIVYAAADGTLETSPD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KQNGTVVQYLPTLQEKKVIPCPPFYESDHPVRVLDVLWIGTYVFAIVYAAADGTLETSPD
             260       270       280       290       300       310 

              280       290       300       310       320       330
pF1KSD VVMALLPKKEEKHPEIFVNFMEPCYGSCTERQHHYYLSYIEEWDLVLAASAASTEVSILA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VVMALLPKKEEKHPEIFVNFMEPCYGSCTERQHHYYLSYIEEWDLVLAASAASTEVSILA
             320       330       340       350       360       370 

              340       350       360       370       380       390
pF1KSD RQSDQINWESWLLEDSSRAELPVTDKSDDSLPMGVVVDYTNQVEITISDEKTLPPAPVLM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RQSDQINWESWLLEDSSRAELPVTDKSDDSLPMGVVVDYTNQVEITISDEKTLPPAPVLM
             380       390       400       410       420       430 

              400       410       420       430       440       450
pF1KSD LLSTDGVLCPFYMINQNPGVKSLIKTPERLSLEGERQPKSPGSTPTTPTSSQAPQKLDAS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LLSTDGVLCPFYMINQNPGVKSLIKTPERLSLEGERQPKSPGSTPTTPTSSQAPQKLDAS
             440       450       460       470       480       490 

              460       470       480       490       500       510
pF1KSD AAAAPASLPPSSPAAPIATFSLLPAGGAPTVFSFGSSSLKSSATVTGEPPSYSSGSDSSK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 AAAAPASLPPSSPAAPIATFSLLPAGGAPTVFSFGSSSLKSSATVTGEPPSYSSGSDSSK
             500       510       520       530       540       550 

              520       530       540       550       560       570
pF1KSD AAPGPGPSTFSFVPPSKASLAPTPAASPVAPSAASFSFGSSGFKPTLESTPVPSVSAPNI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 AAPGPGPSTFSFVPPSKASLAPTPAASPVAPSAASFSFGSSGFKPTLESTPVPSVSAPNI
             560       570       580       590       600       610 

              580                  590       600       610         
pF1KSD AMKPSFPPSTSAVKVNLSE-----------NSSQSAPPMSPFSSASKPAASGPLSHPTPL
       :::::::::::::::::::           .:::::::::::::::::::::::::::::
XP_005 AMKPSFPPSTSAVKVNLSEKFTAAATSTPVSSSQSAPPMSPFSSASKPAASGPLSHPTPL
             620       630       640       650       660       670 

     620       630        640       650       660       670        
pF1KSD SAPPSSVPLKSSVLPSPS-GRSAQGSSSPVPSMVQKSPRITPPAAKPGSPQAKSLQPAVA
       :::::::::::::::::: :::::::::::::::::::::::::::::::::::::::::
XP_005 SAPPSSVPLKSSVLPSPSAGRSAQGSSSPVPSMVQKSPRITPPAAKPGSPQAKSLQPAVA
             680       690       700       710       720       730 

      680       690       700       710       720       730        
pF1KSD EKQGHQWKDSDPVMAGIGEEIAHFQKELEELKARTSKACFQVGTSEEMKMLRTESDDLHT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EKQGHQWKDSDPVMAGIGEEIAHFQKELEELKARTSKACFQVGTSEEMKMLRTESDDLHT
             740       750       760       770       780       790 

      740       750       760       770       780       790        
pF1KSD FLLEIKETTESLHGDISSLKTTLLEGFAGVEEAREQNERNRDSGYLHLLYKRPLDPKSEA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 FLLEIKETTESLHGDISSLKTTLLEGFAGVEEAREQNERNRDSGYLHLLYKRPLDPKSEA
             800       810       820       830       840       850 

      800       810       820       830       840       850        
pF1KSD QLQEIRRLHQYVKFAVQDVNDVLDLEWDQHLEQKKKQRHLLVPERETLFNTLANNREIIN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QLQEIRRLHQYVKFAVQDVNDVLDLEWDQHLEQKKKQRHLLVPERETLFNTLANNREIIN
             860       870       880       890       900       910 

      860       870       880       890       900       910        
pF1KSD QQRKRLNHLVDSLQQLRLYKQTSLWSLSSAVPSQSSIHSFDSDLESLCNALLKTTIESHT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QQRKRLNHLVDSLQQLRLYKQTSLWSLSSAVPSQSSIHSFDSDLESLCNALLKTTIESHT
             920       930       940       950       960       970 

      920       930       940       950       960       970        
pF1KSD KSLPKVPAKLSPMKQAQLRNFLAKRKTPPVRSTAPASLSRSAFLSQRYYEDLDEVSSTSS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KSLPKVPAKLSPMKQAQLRNFLAKRKTPPVRSTAPASLSRSAFLSQRYYEDLDEVSSTSS
             980       990      1000      1010      1020      1030 

      980       990      1000      1010      1020      1030        
pF1KSD VSQSLESEDARTSCKDDEAVVQAPRHAPVVRTPSIQPSLLPHAAPFAKSHLVHGSSPGVM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VSQSLESEDARTSCKDDEAVVQAPRHAPVVRTPSIQPSLLPHAAPFAKSHLVHGSSPGVM
            1040      1050      1060      1070      1080      1090 

     1040      1050      1060      1070      1080      1090        
pF1KSD GTSVATSASKIIPQGADSTMLATKTVKHGAPSPSHPISAPQAAAAAALRRQMASQAPAVN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GTSVATSASKIIPQGADSTMLATKTVKHGAPSPSHPISAPQAAAAAALRRQMASQAPAVN
            1100      1110      1120      1130      1140      1150 

     1100      1110      1120                1130      1140        
pF1KSD TLTESTLKNVPQVVNVQELKNNPATPSTA----------KTPHPVLTPVAANQAKQGSLI
       :::::::::::::::::::::::::::::          :::::::::::::::::::::
XP_005 TLTESTLKNVPQVVNVQELKNNPATPSTAMGSSVPYSTAKTPHPVLTPVAANQAKQGSLI
            1160      1170      1180      1190      1200      1210 

     1150      1160      1170      1180      1190      1200        
pF1KSD NSLKPSGPTPASGQLSSGDKASGTAKIETAVTSTPSASGQFSKPFSFSPSGTGFNFGIIT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 NSLKPSGPTPASGQLSSGDKASGTAKIETAVTSTPSASGQFSKPFSFSPSGTGFNFGIIT
            1220      1230      1240      1250      1260      1270 

     1210      1220      1230      1240      1250      1260        
pF1KSD PTPSSNFTAAQGATPSTKESSQPDAFSSGGGSKPSYEAIPESSPPSGITSASNTTPGEPA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PTPSSNFTAAQGATPSTKESSQPDAFSSGGGSKPSYEAIPESSPPSGITSASNTTPGEPA
            1280      1290      1300      1310      1320      1330 

     1270      1280      1290      1300      1310      1320        
pF1KSD ASSSRPVAPSGTALSTTSSKLETPPSKLGELLFPSSLAGETLGSFSGLRVGQADDSTKPT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ASSSRPVAPSGTALSTTSSKLETPPSKLGELLFPSSLAGETLGSFSGLRVGQADDSTKPT
            1340      1350      1360      1370      1380      1390 

     1330      1340      1350      1360      1370      1380        
pF1KSD NKASSTSLTSTQPTKTSGVPSGFNFTAPPVLGKHTEPPVTSSATTTSVAPPAATSTSSTA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 NKASSTSLTSTQPTKTSGVPSGFNFTAPPVLGKHTEPPVTSSATTTSVAPPAATSTSSTA
            1400      1410      1420      1430      1440      1450 

     1390      1400      1410      1420      1430      1440        
pF1KSD VFGSLPVTSAGSSGVISFGGTSLSAGKTSFSFGSQQTNSTVPPSAPPPTTAATPLPTSFP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VFGSLPVTSAGSSGVISFGGTSLSAGKTSFSFGSQQTNSTVPPSAPPPTTAATPLPTSFP
            1460      1470      1480      1490      1500      1510 

     1450      1460      1470      1480      1490      1500        
pF1KSD TLSFGSLLSSATTPSLPMSAGRSTEEATSSALPEKPGDSEVSASAASLLEEQQSAQLPQA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TLSFGSLLSSATTPSLPMSAGRSTEEATSSALPEKPGDSEVSASAASLLEEQQSAQLPQA
            1520      1530      1540      1550      1560      1570 

     1510      1520      1530      1540      1550      1560        
pF1KSD PPQTSDSVKKEPVLAQPAVSNSGTAASSTSLVALSAEATPATTGVPDARTEAVPPASSFS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PPQTSDSVKKEPVLAQPAVSNSGTAASSTSLVALSAEATPATTGVPDARTEAVPPASSFS
            1580      1590      1600      1610      1620      1630 

     1570      1580      1590      1600      1610      1620        
pF1KSD VPGQTAVTAAAISSAGPVAVETSSTPIASSTTSIVAPGPSAEAAAFGTVTSGSSVFAQPP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VPGQTAVTAAAISSAGPVAVETSSTPIASSTTSIVAPGPSAEAAAFGTVTSGSSVFAQPP
            1640      1650      1660      1670      1680      1690 

     1630      1640      1650      1660      1670      1680        
pF1KSD AASSSSAFNQLTNNTATAPSATPVFGQVAASTAPSLFGQQTGSTASTAAATPQVSSSGFS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 AASSSSAFNQLTNNTATAPSATPVFGQVAASTAPSLFGQQTGSTASTAAATPQVSSSGFS
            1700      1710      1720      1730      1740      1750 

     1690      1700      1710      1720      1730      1740        
pF1KSD SPAFGTTAPGVFGQTTFGQASVFGQSASSAASVFSFSQPGFSSVPAFGQPASSTPTSTSG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SPAFGTTAPGVFGQTTFGQASVFGQSASSAASVFSFSQPGFSSVPAFGQPASSTPTSTSG
            1760      1770      1780      1790      1800      1810 

     1750      1760      1770      1780      1790      1800        
pF1KSD SVFGAASSTSSSSSFSFGQSSPNTGGGLFGQSNAPAFGQSPGFGQGGSVFGGTSAATTTA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SVFGAASSTSSSSSFSFGQSSPNTGGGLFGQSNAPAFGQSPGFGQGGSVFGGTSAATTTA
            1820      1830      1840      1850      1860      1870 

     1810      1820      1830      1840      1850      1860        
pF1KSD ATSGFSFCQASGFGSSNTGSVFGQAASTGGIVFGQQSSSSSGSVFGSGNTGRGGGFFSGL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ATSGFSFCQASGFGSSNTGSVFGQAASTGGIVFGQQSSSSSGSVFGSGNTGRGGGFFSGL
            1880      1890      1900      1910      1920      1930 

     1870      1880      1890      1900      1910      1920        
pF1KSD GGKPSQDAANKNPFSSASGGFGSTATSNTSNLFGNSGAKTFGGFASSSFGEQKPTGTFSS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GGKPSQDAANKNPFSSASGGFGSTATSNTSNLFGNSGAKTFGGFASSSFGEQKPTGTFSS
            1940      1950      1960      1970      1980      1990 

     1930      1940      1950      1960      1970      1980        
pF1KSD GGGSVASQGFGFSSPNKTGGFGAAPVFGSPPTFGGSPGFGGVPAFGSAPAFTSPLGSTGG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GGGSVASQGFGFSSPNKTGGFGAAPVFGSPPTFGGSPGFGGVPAFGSAPAFTSPLGSTGG
            2000      2010      2020      2030      2040      2050 

     1990      2000      2010      2020      2030      2040        
pF1KSD KVFGEGTAAASAGGFGSLAMSLSPTLKGRLLLMRPKAGGGREQAAPGRKSNESRSLGHLC
       :::::::::::::::: .. : . :  : :  .   . :.  : . :  .. :       
XP_005 KVFGEGTAAASAGGFG-FGSSSNTTSFGTLASQNAPTFGSLSQQTSGFGTQSSGFSGFGS
            2060       2070      2080      2090      2100      2110

     2050      2060      2070      2080      2090   
pF1KSD MERALTSPLKVWEQQQHHILRHARESECPHFRITVPTDFWFWDPE
                                                    
XP_005 GTGGFSFGSNNSSVQGFGGWRS                       
             2120      2130                         

>>NP_005076 (OMIM: 114350,613065) nuclear pore complex p  (2090 aa)
 initn: 9592 init1: 5595 opt: 5917  Z-score: 2229.5  bits: 426.2 E(85289): 1.9e-117
Smith-Waterman score: 12879; 97.5% identity (98.0% similar) in 2062 aa overlap (1-2041:1-2061)

               10        20        30        40        50        60
pF1KSD MGDEMDAMIPEREMKDFQFRALKKVRIFDSPEELPKERSSLLAVSNKYGLVFAGGASGLQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 MGDEMDAMIPEREMKDFQFRALKKVRIFDSPEELPKERSSLLAVSNKYGLVFAGGASGLQ
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KSD IFPTKNLLIQNKPGDDPNKIVDKVQGLLVPMKFPIHHLALSCDNLTLSACMMSSEYGSII
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 IFPTKNLLIQNKPGDDPNKIVDKVQGLLVPMKFPIHHLALSCDNLTLSACMMSSEYGSII
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KSD AFFDVRTFSNEAKQQKRPFAYHKLLKDAGGMVIDMKWNPTVPSMVAVCLADGSIAVLQVT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 AFFDVRTFSNEAKQQKRPFAYHKLLKDAGGMVIDMKWNPTVPSMVAVCLADGSIAVLQVT
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KSD ETVKVCATLPSTVAVTSVCWSPKGKQLAVGKQNGTVVQYLPTLQEKKVIPCPPFYESDHP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 ETVKVCATLPSTVAVTSVCWSPKGKQLAVGKQNGTVVQYLPTLQEKKVIPCPPFYESDHP
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KSD VRVLDVLWIGTYVFAIVYAAADGTLETSPDVVMALLPKKEEKHPEIFVNFMEPCYGSCTE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 VRVLDVLWIGTYVFAIVYAAADGTLETSPDVVMALLPKKEEKHPEIFVNFMEPCYGSCTE
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KSD RQHHYYLSYIEEWDLVLAASAASTEVSILARQSDQINWESWLLEDSSRAELPVTDKSDDS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 RQHHYYLSYIEEWDLVLAASAASTEVSILARQSDQINWESWLLEDSSRAELPVTDKSDDS
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KSD LPMGVVVDYTNQVEITISDEKTLPPAPVLMLLSTDGVLCPFYMINQNPGVKSLIKTPERL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 LPMGVVVDYTNQVEITISDEKTLPPAPVLMLLSTDGVLCPFYMINQNPGVKSLIKTPERL
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KSD SLEGERQPKSPGSTPTTPTSSQAPQKLDASAAAAPASLPPSSPAAPIATFSLLPAGGAPT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 SLEGERQPKSPGSTPTTPTSSQAPQKLDASAAAAPASLPPSSPAAPIATFSLLPAGGAPT
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KSD VFSFGSSSLKSSATVTGEPPSYSSGSDSSKAAPGPGPSTFSFVPPSKASLAPTPAASPVA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 VFSFGSSSLKSSATVTGEPPSYSSGSDSSKAAPGPGPSTFSFVPPSKASLAPTPAASPVA
              490       500       510       520       530       540

              550       560       570       580                    
pF1KSD PSAASFSFGSSGFKPTLESTPVPSVSAPNIAMKPSFPPSTSAVKVNLSE-----------
       :::::::::::::::::::::::::::::::::::::::::::::::::           
NP_005 PSAASFSFGSSGFKPTLESTPVPSVSAPNIAMKPSFPPSTSAVKVNLSEKFTAAATSTPV
              550       560       570       580       590       600

     590       600       610       620       630       640         
pF1KSD NSSQSAPPMSPFSSASKPAASGPLSHPTPLSAPPSSVPLKSSVLPSPSGRSAQGSSSPVP
       .:::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 SSSQSAPPMSPFSSASKPAASGPLSHPTPLSAPPSSVPLKSSVLPSPSGRSAQGSSSPVP
              610       620       630       640       650       660

     650       660       670       680       690       700         
pF1KSD SMVQKSPRITPPAAKPGSPQAKSLQPAVAEKQGHQWKDSDPVMAGIGEEIAHFQKELEEL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 SMVQKSPRITPPAAKPGSPQAKSLQPAVAEKQGHQWKDSDPVMAGIGEEIAHFQKELEEL
              670       680       690       700       710       720

     710       720       730       740       750       760         
pF1KSD KARTSKACFQVGTSEEMKMLRTESDDLHTFLLEIKETTESLHGDISSLKTTLLEGFAGVE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 KARTSKACFQVGTSEEMKMLRTESDDLHTFLLEIKETTESLHGDISSLKTTLLEGFAGVE
              730       740       750       760       770       780

     770       780       790       800       810       820         
pF1KSD EAREQNERNRDSGYLHLLYKRPLDPKSEAQLQEIRRLHQYVKFAVQDVNDVLDLEWDQHL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 EAREQNERNRDSGYLHLLYKRPLDPKSEAQLQEIRRLHQYVKFAVQDVNDVLDLEWDQHL
              790       800       810       820       830       840

     830       840       850       860       870       880         
pF1KSD EQKKKQRHLLVPERETLFNTLANNREIINQQRKRLNHLVDSLQQLRLYKQTSLWSLSSAV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 EQKKKQRHLLVPERETLFNTLANNREIINQQRKRLNHLVDSLQQLRLYKQTSLWSLSSAV
              850       860       870       880       890       900

     890       900       910       920       930       940         
pF1KSD PSQSSIHSFDSDLESLCNALLKTTIESHTKSLPKVPAKLSPMKQAQLRNFLAKRKTPPVR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 PSQSSIHSFDSDLESLCNALLKTTIESHTKSLPKVPAKLSPMKQAQLRNFLAKRKTPPVR
              910       920       930       940       950       960

     950       960       970       980       990      1000         
pF1KSD STAPASLSRSAFLSQRYYEDLDEVSSTSSVSQSLESEDARTSCKDDEAVVQAPRHAPVVR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 STAPASLSRSAFLSQRYYEDLDEVSSTSSVSQSLESEDARTSCKDDEAVVQAPRHAPVVR
              970       980       990      1000      1010      1020

    1010      1020      1030      1040      1050      1060         
pF1KSD TPSIQPSLLPHAAPFAKSHLVHGSSPGVMGTSVATSASKIIPQGADSTMLATKTVKHGAP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 TPSIQPSLLPHAAPFAKSHLVHGSSPGVMGTSVATSASKIIPQGADSTMLATKTVKHGAP
             1030      1040      1050      1060      1070      1080

    1070      1080      1090      1100      1110      1120         
pF1KSD SPSHPISAPQAAAAAALRRQMASQAPAVNTLTESTLKNVPQVVNVQELKNNPATPSTA--
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::  
NP_005 SPSHPISAPQAAAAAALRRQMASQAPAVNTLTESTLKNVPQVVNVQELKNNPATPSTAMG
             1090      1100      1110      1120      1130      1140

              1130      1140      1150      1160      1170         
pF1KSD --------KTPHPVLTPVAANQAKQGSLINSLKPSGPTPASGQLSSGDKASGTAKIETAV
               ::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 SSVPYSTAKTPHPVLTPVAANQAKQGSLINSLKPSGPTPASGQLSSGDKASGTAKIETAV
             1150      1160      1170      1180      1190      1200

    1180      1190      1200      1210      1220      1230         
pF1KSD TSTPSASGQFSKPFSFSPSGTGFNFGIITPTPSSNFTAAQGATPSTKESSQPDAFSSGGG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 TSTPSASGQFSKPFSFSPSGTGFNFGIITPTPSSNFTAAQGATPSTKESSQPDAFSSGGG
             1210      1220      1230      1240      1250      1260

    1240      1250      1260      1270      1280      1290         
pF1KSD SKPSYEAIPESSPPSGITSASNTTPGEPAASSSRPVAPSGTALSTTSSKLETPPSKLGEL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 SKPSYEAIPESSPPSGITSASNTTPGEPAASSSRPVAPSGTALSTTSSKLETPPSKLGEL
             1270      1280      1290      1300      1310      1320

    1300      1310      1320      1330      1340      1350         
pF1KSD LFPSSLAGETLGSFSGLRVGQADDSTKPTNKASSTSLTSTQPTKTSGVPSGFNFTAPPVL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 LFPSSLAGETLGSFSGLRVGQADDSTKPTNKASSTSLTSTQPTKTSGVPSGFNFTAPPVL
             1330      1340      1350      1360      1370      1380

    1360      1370      1380      1390      1400      1410         
pF1KSD GKHTEPPVTSSATTTSVAPPAATSTSSTAVFGSLPVTSAGSSGVISFGGTSLSAGKTSFS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 GKHTEPPVTSSATTTSVAPPAATSTSSTAVFGSLPVTSAGSSGVISFGGTSLSAGKTSFS
             1390      1400      1410      1420      1430      1440

    1420      1430      1440      1450      1460      1470         
pF1KSD FGSQQTNSTVPPSAPPPTTAATPLPTSFPTLSFGSLLSSATTPSLPMSAGRSTEEATSSA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 FGSQQTNSTVPPSAPPPTTAATPLPTSFPTLSFGSLLSSATTPSLPMSAGRSTEEATSSA
             1450      1460      1470      1480      1490      1500

    1480      1490      1500      1510      1520      1530         
pF1KSD LPEKPGDSEVSASAASLLEEQQSAQLPQAPPQTSDSVKKEPVLAQPAVSNSGTAASSTSL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 LPEKPGDSEVSASAASLLEEQQSAQLPQAPPQTSDSVKKEPVLAQPAVSNSGTAASSTSL
             1510      1520      1530      1540      1550      1560

    1540      1550      1560      1570      1580      1590         
pF1KSD VALSAEATPATTGVPDARTEAVPPASSFSVPGQTAVTAAAISSAGPVAVETSSTPIASST
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 VALSAEATPATTGVPDARTEAVPPASSFSVPGQTAVTAAAISSAGPVAVETSSTPIASST
             1570      1580      1590      1600      1610      1620

    1600      1610      1620      1630      1640      1650         
pF1KSD TSIVAPGPSAEAAAFGTVTSGSSVFAQPPAASSSSAFNQLTNNTATAPSATPVFGQVAAS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 TSIVAPGPSAEAAAFGTVTSGSSVFAQPPAASSSSAFNQLTNNTATAPSATPVFGQVAAS
             1630      1640      1650      1660      1670      1680

    1660      1670      1680      1690      1700      1710         
pF1KSD TAPSLFGQQTGSTASTAAATPQVSSSGFSSPAFGTTAPGVFGQTTFGQASVFGQSASSAA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 TAPSLFGQQTGSTASTAAATPQVSSSGFSSPAFGTTAPGVFGQTTFGQASVFGQSASSAA
             1690      1700      1710      1720      1730      1740

    1720      1730      1740      1750      1760      1770         
pF1KSD SVFSFSQPGFSSVPAFGQPASSTPTSTSGSVFGAASSTSSSSSFSFGQSSPNTGGGLFGQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 SVFSFSQPGFSSVPAFGQPASSTPTSTSGSVFGAASSTSSSSSFSFGQSSPNTGGGLFGQ
             1750      1760      1770      1780      1790      1800

    1780      1790      1800      1810      1820      1830         
pF1KSD SNAPAFGQSPGFGQGGSVFGGTSAATTTAATSGFSFCQASGFGSSNTGSVFGQAASTGGI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 SNAPAFGQSPGFGQGGSVFGGTSAATTTAATSGFSFCQASGFGSSNTGSVFGQAASTGGI
             1810      1820      1830      1840      1850      1860

    1840      1850      1860      1870      1880      1890         
pF1KSD VFGQQSSSSSGSVFGSGNTGRGGGFFSGLGGKPSQDAANKNPFSSASGGFGSTATSNTSN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 VFGQQSSSSSGSVFGSGNTGRGGGFFSGLGGKPSQDAANKNPFSSASGGFGSTATSNTSN
             1870      1880      1890      1900      1910      1920

    1900      1910      1920      1930      1940      1950         
pF1KSD LFGNSGAKTFGGFASSSFGEQKPTGTFSSGGGSVASQGFGFSSPNKTGGFGAAPVFGSPP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 LFGNSGAKTFGGFASSSFGEQKPTGTFSSGGGSVASQGFGFSSPNKTGGFGAAPVFGSPP
             1930      1940      1950      1960      1970      1980

    1960      1970      1980      1990      2000      2010         
pF1KSD TFGGSPGFGGVPAFGSAPAFTSPLGSTGGKVFGEGTAAASAGGFGSLAMSLSPTLKGRLL
       ::::::::::::::::::::::::::::::::::::::::::::: .. : . :  : : 
NP_005 TFGGSPGFGGVPAFGSAPAFTSPLGSTGGKVFGEGTAAASAGGFG-FGSSSNTTSFGTLA
             1990      2000      2010      2020       2030         

    2020      2030      2040      2050      2060      2070         
pF1KSD LMRPKAGGGREQAAPGRKSNESRSLGHLCMERALTSPLKVWEQQQHHILRHARESECPHF
        .   . :.  : . :  .. :                                      
NP_005 SQNAPTFGSLSQQTSGFGTQSSGFSGFGSGTGGFSFGSNNSSVQGFGGWRS         
    2040      2050      2060      2070      2080      2090         

>>NP_001305253 (OMIM: 114350,613065) nuclear pore comple  (2080 aa)
 initn: 9858 init1: 5595 opt: 5887  Z-score: 2218.4  bits: 424.1 E(85289): 8e-117
Smith-Waterman score: 12905; 98.1% identity (98.5% similar) in 2052 aa overlap (1-2041:1-2051)

               10        20        30        40        50        60
pF1KSD MGDEMDAMIPEREMKDFQFRALKKVRIFDSPEELPKERSSLLAVSNKYGLVFAGGASGLQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MGDEMDAMIPEREMKDFQFRALKKVRIFDSPEELPKERSSLLAVSNKYGLVFAGGASGLQ
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KSD IFPTKNLLIQNKPGDDPNKIVDKVQGLLVPMKFPIHHLALSCDNLTLSACMMSSEYGSII
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IFPTKNLLIQNKPGDDPNKIVDKVQGLLVPMKFPIHHLALSCDNLTLSACMMSSEYGSII
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KSD AFFDVRTFSNEAKQQKRPFAYHKLLKDAGGMVIDMKWNPTVPSMVAVCLADGSIAVLQVT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AFFDVRTFSNEAKQQKRPFAYHKLLKDAGGMVIDMKWNPTVPSMVAVCLADGSIAVLQVT
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KSD ETVKVCATLPSTVAVTSVCWSPKGKQLAVGKQNGTVVQYLPTLQEKKVIPCPPFYESDHP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ETVKVCATLPSTVAVTSVCWSPKGKQLAVGKQNGTVVQYLPTLQEKKVIPCPPFYESDHP
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KSD VRVLDVLWIGTYVFAIVYAAADGTLETSPDVVMALLPKKEEKHPEIFVNFMEPCYGSCTE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VRVLDVLWIGTYVFAIVYAAADGTLETSPDVVMALLPKKEEKHPEIFVNFMEPCYGSCTE
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KSD RQHHYYLSYIEEWDLVLAASAASTEVSILARQSDQINWESWLLEDSSRAELPVTDKSDDS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RQHHYYLSYIEEWDLVLAASAASTEVSILARQSDQINWESWLLEDSSRAELPVTDKSDDS
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KSD LPMGVVVDYTNQVEITISDEKTLPPAPVLMLLSTDGVLCPFYMINQNPGVKSLIKTPERL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LPMGVVVDYTNQVEITISDEKTLPPAPVLMLLSTDGVLCPFYMINQNPGVKSLIKTPERL
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KSD SLEGERQPKSPGSTPTTPTSSQAPQKLDASAAAAPASLPPSSPAAPIATFSLLPAGGAPT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SLEGERQPKSPGSTPTTPTSSQAPQKLDASAAAAPASLPPSSPAAPIATFSLLPAGGAPT
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KSD VFSFGSSSLKSSATVTGEPPSYSSGSDSSKAAPGPGPSTFSFVPPSKASLAPTPAASPVA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VFSFGSSSLKSSATVTGEPPSYSSGSDSSKAAPGPGPSTFSFVPPSKASLAPTPAASPVA
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KSD PSAASFSFGSSGFKPTLESTPVPSVSAPNIAMKPSFPPSTSAVKVNLSENSSQSAPPMSP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PSAASFSFGSSGFKPTLESTPVPSVSAPNIAMKPSFPPSTSAVKVNLSENSSQSAPPMSP
              550       560       570       580       590       600

              610       620       630        640       650         
pF1KSD FSSASKPAASGPLSHPTPLSAPPSSVPLKSSVLPSPS-GRSAQGSSSPVPSMVQKSPRIT
       ::::::::::::::::::::::::::::::::::::: ::::::::::::::::::::::
NP_001 FSSASKPAASGPLSHPTPLSAPPSSVPLKSSVLPSPSAGRSAQGSSSPVPSMVQKSPRIT
              610       620       630       640       650       660

     660       670       680       690       700       710         
pF1KSD PPAAKPGSPQAKSLQPAVAEKQGHQWKDSDPVMAGIGEEIAHFQKELEELKARTSKACFQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PPAAKPGSPQAKSLQPAVAEKQGHQWKDSDPVMAGIGEEIAHFQKELEELKARTSKACFQ
              670       680       690       700       710       720

     720       730       740       750       760       770         
pF1KSD VGTSEEMKMLRTESDDLHTFLLEIKETTESLHGDISSLKTTLLEGFAGVEEAREQNERNR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VGTSEEMKMLRTESDDLHTFLLEIKETTESLHGDISSLKTTLLEGFAGVEEAREQNERNR
              730       740       750       760       770       780

     780       790       800       810       820       830         
pF1KSD DSGYLHLLYKRPLDPKSEAQLQEIRRLHQYVKFAVQDVNDVLDLEWDQHLEQKKKQRHLL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DSGYLHLLYKRPLDPKSEAQLQEIRRLHQYVKFAVQDVNDVLDLEWDQHLEQKKKQRHLL
              790       800       810       820       830       840

     840       850       860       870       880       890         
pF1KSD VPERETLFNTLANNREIINQQRKRLNHLVDSLQQLRLYKQTSLWSLSSAVPSQSSIHSFD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VPERETLFNTLANNREIINQQRKRLNHLVDSLQQLRLYKQTSLWSLSSAVPSQSSIHSFD
              850       860       870       880       890       900

     900       910       920       930       940       950         
pF1KSD SDLESLCNALLKTTIESHTKSLPKVPAKLSPMKQAQLRNFLAKRKTPPVRSTAPASLSRS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SDLESLCNALLKTTIESHTKSLPKVPAKLSPMKQAQLRNFLAKRKTPPVRSTAPASLSRS
              910       920       930       940       950       960

     960       970       980       990      1000      1010         
pF1KSD AFLSQRYYEDLDEVSSTSSVSQSLESEDARTSCKDDEAVVQAPRHAPVVRTPSIQPSLLP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AFLSQRYYEDLDEVSSTSSVSQSLESEDARTSCKDDEAVVQAPRHAPVVRTPSIQPSLLP
              970       980       990      1000      1010      1020

    1020      1030      1040      1050      1060      1070         
pF1KSD HAAPFAKSHLVHGSSPGVMGTSVATSASKIIPQGADSTMLATKTVKHGAPSPSHPISAPQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HAAPFAKSHLVHGSSPGVMGTSVATSASKIIPQGADSTMLATKTVKHGAPSPSHPISAPQ
             1030      1040      1050      1060      1070      1080

    1080      1090      1100      1110      1120                   
pF1KSD AAAAAALRRQMASQAPAVNTLTESTLKNVPQVVNVQELKNNPATPSTA----------KT
       ::::::::::::::::::::::::::::::::::::::::::::::::          ::
NP_001 AAAAAALRRQMASQAPAVNTLTESTLKNVPQVVNVQELKNNPATPSTAMGSSVPYSTAKT
             1090      1100      1110      1120      1130      1140

    1130      1140      1150      1160      1170      1180         
pF1KSD PHPVLTPVAANQAKQGSLINSLKPSGPTPASGQLSSGDKASGTAKIETAVTSTPSASGQF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PHPVLTPVAANQAKQGSLINSLKPSGPTPASGQLSSGDKASGTAKIETAVTSTPSASGQF
             1150      1160      1170      1180      1190      1200

    1190      1200      1210      1220      1230      1240         
pF1KSD SKPFSFSPSGTGFNFGIITPTPSSNFTAAQGATPSTKESSQPDAFSSGGGSKPSYEAIPE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SKPFSFSPSGTGFNFGIITPTPSSNFTAAQGATPSTKESSQPDAFSSGGGSKPSYEAIPE
             1210      1220      1230      1240      1250      1260

    1250      1260      1270      1280      1290      1300         
pF1KSD SSPPSGITSASNTTPGEPAASSSRPVAPSGTALSTTSSKLETPPSKLGELLFPSSLAGET
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SSPPSGITSASNTTPGEPAASSSRPVAPSGTALSTTSSKLETPPSKLGELLFPSSLAGET
             1270      1280      1290      1300      1310      1320

    1310      1320      1330      1340      1350      1360         
pF1KSD LGSFSGLRVGQADDSTKPTNKASSTSLTSTQPTKTSGVPSGFNFTAPPVLGKHTEPPVTS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LGSFSGLRVGQADDSTKPTNKASSTSLTSTQPTKTSGVPSGFNFTAPPVLGKHTEPPVTS
             1330      1340      1350      1360      1370      1380

    1370      1380      1390      1400      1410      1420         
pF1KSD SATTTSVAPPAATSTSSTAVFGSLPVTSAGSSGVISFGGTSLSAGKTSFSFGSQQTNSTV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SATTTSVAPPAATSTSSTAVFGSLPVTSAGSSGVISFGGTSLSAGKTSFSFGSQQTNSTV
             1390      1400      1410      1420      1430      1440

    1430      1440      1450      1460      1470      1480         
pF1KSD PPSAPPPTTAATPLPTSFPTLSFGSLLSSATTPSLPMSAGRSTEEATSSALPEKPGDSEV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PPSAPPPTTAATPLPTSFPTLSFGSLLSSATTPSLPMSAGRSTEEATSSALPEKPGDSEV
             1450      1460      1470      1480      1490      1500

    1490      1500      1510      1520      1530      1540         
pF1KSD SASAASLLEEQQSAQLPQAPPQTSDSVKKEPVLAQPAVSNSGTAASSTSLVALSAEATPA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SASAASLLEEQQSAQLPQAPPQTSDSVKKEPVLAQPAVSNSGTAASSTSLVALSAEATPA
             1510      1520      1530      1540      1550      1560

    1550      1560      1570      1580      1590      1600         
pF1KSD TTGVPDARTEAVPPASSFSVPGQTAVTAAAISSAGPVAVETSSTPIASSTTSIVAPGPSA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TTGVPDARTEAVPPASSFSVPGQTAVTAAAISSAGPVAVETSSTPIASSTTSIVAPGPSA
             1570      1580      1590      1600      1610      1620

    1610      1620      1630      1640      1650      1660         
pF1KSD EAAAFGTVTSGSSVFAQPPAASSSSAFNQLTNNTATAPSATPVFGQVAASTAPSLFGQQT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EAAAFGTVTSGSSVFAQPPAASSSSAFNQLTNNTATAPSATPVFGQVAASTAPSLFGQQT
             1630      1640      1650      1660      1670      1680

    1670      1680      1690      1700      1710      1720         
pF1KSD GSTASTAAATPQVSSSGFSSPAFGTTAPGVFGQTTFGQASVFGQSASSAASVFSFSQPGF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GSTASTAAATPQVSSSGFSSPAFGTTAPGVFGQTTFGQASVFGQSASSAASVFSFSQPGF
             1690      1700      1710      1720      1730      1740

    1730      1740      1750      1760      1770      1780         
pF1KSD SSVPAFGQPASSTPTSTSGSVFGAASSTSSSSSFSFGQSSPNTGGGLFGQSNAPAFGQSP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SSVPAFGQPASSTPTSTSGSVFGAASSTSSSSSFSFGQSSPNTGGGLFGQSNAPAFGQSP
             1750      1760      1770      1780      1790      1800

    1790      1800      1810      1820      1830      1840         
pF1KSD GFGQGGSVFGGTSAATTTAATSGFSFCQASGFGSSNTGSVFGQAASTGGIVFGQQSSSSS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GFGQGGSVFGGTSAATTTAATSGFSFCQASGFGSSNTGSVFGQAASTGGIVFGQQSSSSS
             1810      1820      1830      1840      1850      1860

    1850      1860      1870      1880      1890      1900         
pF1KSD GSVFGSGNTGRGGGFFSGLGGKPSQDAANKNPFSSASGGFGSTATSNTSNLFGNSGAKTF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GSVFGSGNTGRGGGFFSGLGGKPSQDAANKNPFSSASGGFGSTATSNTSNLFGNSGAKTF
             1870      1880      1890      1900      1910      1920

    1910      1920      1930      1940      1950      1960         
pF1KSD GGFASSSFGEQKPTGTFSSGGGSVASQGFGFSSPNKTGGFGAAPVFGSPPTFGGSPGFGG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GGFASSSFGEQKPTGTFSSGGGSVASQGFGFSSPNKTGGFGAAPVFGSPPTFGGSPGFGG
             1930      1940      1950      1960      1970      1980

    1970      1980      1990      2000      2010      2020         
pF1KSD VPAFGSAPAFTSPLGSTGGKVFGEGTAAASAGGFGSLAMSLSPTLKGRLLLMRPKAGGGR
       ::::::::::::::::::::::::::::::::::: .. : . :  : :  .   . :. 
NP_001 VPAFGSAPAFTSPLGSTGGKVFGEGTAAASAGGFG-FGSSSNTTSFGTLASQNAPTFGSL
             1990      2000      2010       2020      2030         

    2030      2040      2050      2060      2070      2080         
pF1KSD EQAAPGRKSNESRSLGHLCMERALTSPLKVWEQQQHHILRHARESECPHFRITVPTDFWF
        : . :  .. :                                                
NP_001 SQQTSGFGTQSSGFSGFGSGTGGFSFGSNNSSVQGFGGWRS                   
    2040      2050      2060      2070      2080                   

>>XP_016870656 (OMIM: 114350,613065) PREDICTED: nuclear   (2119 aa)
 initn: 9557 init1: 5595 opt: 5878  Z-score: 2214.9  bits: 423.5 E(85289): 1.2e-116
Smith-Waterman score: 12900; 98.0% identity (98.5% similar) in 2051 aa overlap (1-2041:42-2090)

                                             10        20        30
pF1KSD                               MGDEMDAMIPEREMKDFQFRALKKVRIFDS
                                     ::::::::::::::::::::::::::::::
XP_016 GRKFAVERPGFRGQGRGRQRWLLRHTEGGAMGDEMDAMIPEREMKDFQFRALKKVRIFDS
              20        30        40        50        60        70 

               40        50        60        70        80        90
pF1KSD PEELPKERSSLLAVSNKYGLVFAGGASGLQIFPTKNLLIQNKPGDDPNKIVDKVQGLLVP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PEELPKERSSLLAVSNKYGLVFAGGASGLQIFPTKNLLIQNKPGDDPNKIVDKVQGLLVP
              80        90       100       110       120       130 

              100       110       120       130       140       150
pF1KSD MKFPIHHLALSCDNLTLSACMMSSEYGSIIAFFDVRTFSNEAKQQKRPFAYHKLLKDAGG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MKFPIHHLALSCDNLTLSACMMSSEYGSIIAFFDVRTFSNEAKQQKRPFAYHKLLKDAGG
             140       150       160       170       180       190 

              160       170       180       190       200       210
pF1KSD MVIDMKWNPTVPSMVAVCLADGSIAVLQVTETVKVCATLPSTVAVTSVCWSPKGKQLAVG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MVIDMKWNPTVPSMVAVCLADGSIAVLQVTETVKVCATLPSTVAVTSVCWSPKGKQLAVG
             200       210       220       230       240       250 

              220       230       240       250       260       270
pF1KSD KQNGTVVQYLPTLQEKKVIPCPPFYESDHPVRVLDVLWIGTYVFAIVYAAADGTLETSPD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KQNGTVVQYLPTLQEKKVIPCPPFYESDHPVRVLDVLWIGTYVFAIVYAAADGTLETSPD
             260       270       280       290       300       310 

              280       290       300       310       320       330
pF1KSD VVMALLPKKEEKHPEIFVNFMEPCYGSCTERQHHYYLSYIEEWDLVLAASAASTEVSILA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VVMALLPKKEEKHPEIFVNFMEPCYGSCTERQHHYYLSYIEEWDLVLAASAASTEVSILA
             320       330       340       350       360       370 

              340       350       360       370       380       390
pF1KSD RQSDQINWESWLLEDSSRAELPVTDKSDDSLPMGVVVDYTNQVEITISDEKTLPPAPVLM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RQSDQINWESWLLEDSSRAELPVTDKSDDSLPMGVVVDYTNQVEITISDEKTLPPAPVLM
             380       390       400       410       420       430 

              400       410       420       430       440       450
pF1KSD LLSTDGVLCPFYMINQNPGVKSLIKTPERLSLEGERQPKSPGSTPTTPTSSQAPQKLDAS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LLSTDGVLCPFYMINQNPGVKSLIKTPERLSLEGERQPKSPGSTPTTPTSSQAPQKLDAS
             440       450       460       470       480       490 

              460       470       480       490       500       510
pF1KSD AAAAPASLPPSSPAAPIATFSLLPAGGAPTVFSFGSSSLKSSATVTGEPPSYSSGSDSSK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AAAAPASLPPSSPAAPIATFSLLPAGGAPTVFSFGSSSLKSSATVTGEPPSYSSGSDSSK
             500       510       520       530       540       550 

              520       530       540       550       560       570
pF1KSD AAPGPGPSTFSFVPPSKASLAPTPAASPVAPSAASFSFGSSGFKPTLESTPVPSVSAPNI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AAPGPGPSTFSFVPPSKASLAPTPAASPVAPSAASFSFGSSGFKPTLESTPVPSVSAPNI
             560       570       580       590       600       610 

              580       590       600       610       620       630
pF1KSD AMKPSFPPSTSAVKVNLSENSSQSAPPMSPFSSASKPAASGPLSHPTPLSAPPSSVPLKS
       ::::::::::::::::::::: ::::::::::::::::::::::::::::::::::::::
XP_016 AMKPSFPPSTSAVKVNLSENS-QSAPPMSPFSSASKPAASGPLSHPTPLSAPPSSVPLKS
             620       630        640       650       660       670

              640       650       660       670       680       690
pF1KSD SVLPSPSGRSAQGSSSPVPSMVQKSPRITPPAAKPGSPQAKSLQPAVAEKQGHQWKDSDP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SVLPSPSGRSAQGSSSPVPSMVQKSPRITPPAAKPGSPQAKSLQPAVAEKQGHQWKDSDP
              680       690       700       710       720       730

              700       710       720       730       740       750
pF1KSD VMAGIGEEIAHFQKELEELKARTSKACFQVGTSEEMKMLRTESDDLHTFLLEIKETTESL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VMAGIGEEIAHFQKELEELKARTSKACFQVGTSEEMKMLRTESDDLHTFLLEIKETTESL
              740       750       760       770       780       790

              760       770       780       790       800       810
pF1KSD HGDISSLKTTLLEGFAGVEEAREQNERNRDSGYLHLLYKRPLDPKSEAQLQEIRRLHQYV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HGDISSLKTTLLEGFAGVEEAREQNERNRDSGYLHLLYKRPLDPKSEAQLQEIRRLHQYV
              800       810       820       830       840       850

              820       830       840       850       860       870
pF1KSD KFAVQDVNDVLDLEWDQHLEQKKKQRHLLVPERETLFNTLANNREIINQQRKRLNHLVDS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KFAVQDVNDVLDLEWDQHLEQKKKQRHLLVPERETLFNTLANNREIINQQRKRLNHLVDS
              860       870       880       890       900       910

              880       890       900       910       920       930
pF1KSD LQQLRLYKQTSLWSLSSAVPSQSSIHSFDSDLESLCNALLKTTIESHTKSLPKVPAKLSP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LQQLRLYKQTSLWSLSSAVPSQSSIHSFDSDLESLCNALLKTTIESHTKSLPKVPAKLSP
              920       930       940       950       960       970

              940       950       960       970       980       990
pF1KSD MKQAQLRNFLAKRKTPPVRSTAPASLSRSAFLSQRYYEDLDEVSSTSSVSQSLESEDART
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MKQAQLRNFLAKRKTPPVRSTAPASLSRSAFLSQRYYEDLDEVSSTSSVSQSLESEDART
              980       990      1000      1010      1020      1030

             1000      1010      1020      1030      1040      1050
pF1KSD SCKDDEAVVQAPRHAPVVRTPSIQPSLLPHAAPFAKSHLVHGSSPGVMGTSVATSASKII
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SCKDDEAVVQAPRHAPVVRTPSIQPSLLPHAAPFAKSHLVHGSSPGVMGTSVATSASKII
             1040      1050      1060      1070      1080      1090

             1060      1070      1080      1090      1100      1110
pF1KSD PQGADSTMLATKTVKHGAPSPSHPISAPQAAAAAALRRQMASQAPAVNTLTESTLKNVPQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PQGADSTMLATKTVKHGAPSPSHPISAPQAAAAAALRRQMASQAPAVNTLTESTLKNVPQ
             1100      1110      1120      1130      1140      1150

             1120                1130      1140      1150      1160
pF1KSD VVNVQELKNNPATPSTA----------KTPHPVLTPVAANQAKQGSLINSLKPSGPTPAS
       :::::::::::::::::          :::::::::::::::::::::::::::::::::
XP_016 VVNVQELKNNPATPSTAMGSSVPYSTAKTPHPVLTPVAANQAKQGSLINSLKPSGPTPAS
             1160      1170      1180      1190      1200      1210

             1170      1180      1190      1200      1210      1220
pF1KSD GQLSSGDKASGTAKIETAVTSTPSASGQFSKPFSFSPSGTGFNFGIITPTPSSNFTAAQG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GQLSSGDKASGTAKIETAVTSTPSASGQFSKPFSFSPSGTGFNFGIITPTPSSNFTAAQG
             1220      1230      1240      1250      1260      1270

             1230      1240      1250      1260      1270      1280
pF1KSD ATPSTKESSQPDAFSSGGGSKPSYEAIPESSPPSGITSASNTTPGEPAASSSRPVAPSGT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ATPSTKESSQPDAFSSGGGSKPSYEAIPESSPPSGITSASNTTPGEPAASSSRPVAPSGT
             1280      1290      1300      1310      1320      1330

             1290      1300      1310      1320      1330      1340
pF1KSD ALSTTSSKLETPPSKLGELLFPSSLAGETLGSFSGLRVGQADDSTKPTNKASSTSLTSTQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ALSTTSSKLETPPSKLGELLFPSSLAGETLGSFSGLRVGQADDSTKPTNKASSTSLTSTQ
             1340      1350      1360      1370      1380      1390

             1350      1360      1370      1380      1390      1400
pF1KSD PTKTSGVPSGFNFTAPPVLGKHTEPPVTSSATTTSVAPPAATSTSSTAVFGSLPVTSAGS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PTKTSGVPSGFNFTAPPVLGKHTEPPVTSSATTTSVAPPAATSTSSTAVFGSLPVTSAGS
             1400      1410      1420      1430      1440      1450

             1410      1420      1430      1440      1450      1460
pF1KSD SGVISFGGTSLSAGKTSFSFGSQQTNSTVPPSAPPPTTAATPLPTSFPTLSFGSLLSSAT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SGVISFGGTSLSAGKTSFSFGSQQTNSTVPPSAPPPTTAATPLPTSFPTLSFGSLLSSAT
             1460      1470      1480      1490      1500      1510

             1470      1480      1490      1500      1510      1520
pF1KSD TPSLPMSAGRSTEEATSSALPEKPGDSEVSASAASLLEEQQSAQLPQAPPQTSDSVKKEP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TPSLPMSAGRSTEEATSSALPEKPGDSEVSASAASLLEEQQSAQLPQAPPQTSDSVKKEP
             1520      1530      1540      1550      1560      1570

             1530      1540      1550      1560      1570      1580
pF1KSD VLAQPAVSNSGTAASSTSLVALSAEATPATTGVPDARTEAVPPASSFSVPGQTAVTAAAI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VLAQPAVSNSGTAASSTSLVALSAEATPATTGVPDARTEAVPPASSFSVPGQTAVTAAAI
             1580      1590      1600      1610      1620      1630

             1590      1600      1610      1620      1630      1640
pF1KSD SSAGPVAVETSSTPIASSTTSIVAPGPSAEAAAFGTVTSGSSVFAQPPAASSSSAFNQLT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SSAGPVAVETSSTPIASSTTSIVAPGPSAEAAAFGTVTSGSSVFAQPPAASSSSAFNQLT
             1640      1650      1660      1670      1680      1690

             1650      1660      1670      1680      1690      1700
pF1KSD NNTATAPSATPVFGQVAASTAPSLFGQQTGSTASTAAATPQVSSSGFSSPAFGTTAPGVF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NNTATAPSATPVFGQVAASTAPSLFGQQTGSTASTAAATPQVSSSGFSSPAFGTTAPGVF
             1700      1710      1720      1730      1740      1750

             1710      1720      1730      1740      1750      1760
pF1KSD GQTTFGQASVFGQSASSAASVFSFSQPGFSSVPAFGQPASSTPTSTSGSVFGAASSTSSS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GQTTFGQASVFGQSASSAASVFSFSQPGFSSVPAFGQPASSTPTSTSGSVFGAASSTSSS
             1760      1770      1780      1790      1800      1810

             1770      1780      1790      1800      1810      1820
pF1KSD SSFSFGQSSPNTGGGLFGQSNAPAFGQSPGFGQGGSVFGGTSAATTTAATSGFSFCQASG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SSFSFGQSSPNTGGGLFGQSNAPAFGQSPGFGQGGSVFGGTSAATTTAATSGFSFCQASG
             1820      1830      1840      1850      1860      1870

             1830      1840      1850      1860      1870      1880
pF1KSD FGSSNTGSVFGQAASTGGIVFGQQSSSSSGSVFGSGNTGRGGGFFSGLGGKPSQDAANKN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FGSSNTGSVFGQAASTGGIVFGQQSSSSSGSVFGSGNTGRGGGFFSGLGGKPSQDAANKN
             1880      1890      1900      1910      1920      1930

             1890      1900      1910      1920      1930      1940
pF1KSD PFSSASGGFGSTATSNTSNLFGNSGAKTFGGFASSSFGEQKPTGTFSSGGGSVASQGFGF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PFSSASGGFGSTATSNTSNLFGNSGAKTFGGFASSSFGEQKPTGTFSSGGGSVASQGFGF
             1940      1950      1960      1970      1980      1990

             1950      1960      1970      1980      1990      2000
pF1KSD SSPNKTGGFGAAPVFGSPPTFGGSPGFGGVPAFGSAPAFTSPLGSTGGKVFGEGTAAASA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SSPNKTGGFGAAPVFGSPPTFGGSPGFGGVPAFGSAPAFTSPLGSTGGKVFGEGTAAASA
             2000      2010      2020      2030      2040      2050

             2010      2020      2030      2040      2050      2060
pF1KSD GGFGSLAMSLSPTLKGRLLLMRPKAGGGREQAAPGRKSNESRSLGHLCMERALTSPLKVW
       :::: .. : . :  : :  .   . :.  : . :  .. :                   
XP_016 GGFG-FGSSSNTTSFGTLASQNAPTFGSLSQQTSGFGTQSSGFSGFGSGTGGFSFGSNNS
              2060      2070      2080      2090      2100         

             2070      2080      2090   
pF1KSD EQQQHHILRHARESECPHFRITVPTDFWFWDPE
                                        
XP_016 SVQGFGGWRS                       
    2110                                

>>XP_005272276 (OMIM: 114350,613065) PREDICTED: nuclear   (2036 aa)
 initn: 8862 init1: 5595 opt: 5853  Z-score: 2205.8  bits: 421.7 E(85289): 4e-116
Smith-Waterman score: 12043; 92.8% identity (93.3% similar) in 2063 aa overlap (1-2041:42-2007)

                                             10        20        30
pF1KSD                               MGDEMDAMIPEREMKDFQFRALKKVRIFDS
                                     ::::::::::::::::::::::::::::::
XP_005 GRKFAVERPGFRGQGRGRQRWLLRHTEGGAMGDEMDAMIPEREMKDFQFRALKKVRIFDS
              20        30        40        50        60        70 

               40        50        60        70        80        90
pF1KSD PEELPKERSSLLAVSNKYGLVFAGGASGLQIFPTKNLLIQNKPGDDPNKIVDKVQGLLVP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PEELPKERSSLLAVSNKYGLVFAGGASGLQIFPTKNLLIQNKPGDDPNKIVDKVQGLLVP
              80        90       100       110       120       130 

              100       110       120       130       140       150
pF1KSD MKFPIHHLALSCDNLTLSACMMSSEYGSIIAFFDVRTFSNEAKQQKRPFAYHKLLKDAGG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MKFPIHHLALSCDNLTLSACMMSSEYGSIIAFFDVRTFSNEAKQQKRPFAYHKLLKDAGG
             140       150       160       170       180       190 

              160       170       180       190       200       210
pF1KSD MVIDMKWNPTVPSMVAVCLADGSIAVLQVTETVKVCATLPSTVAVTSVCWSPKGKQLAVG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MVIDMKWNPTVPSMVAVCLADGSIAVLQVTETVKVCATLPSTVAVTSVCWSPKGKQLAVG
             200       210       220       230       240       250 

              220       230       240       250       260       270
pF1KSD KQNGTVVQYLPTLQEKKVIPCPPFYESDHPVRVLDVLWIGTYVFAIVYAAADGTLETSPD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KQNGTVVQYLPTLQEKKVIPCPPFYESDHPVRVLDVLWIGTYVFAIVYAAADGTLETSPD
             260       270       280       290       300       310 

              280       290       300       310       320       330
pF1KSD VVMALLPKKEEKHPEIFVNFMEPCYGSCTERQHHYYLSYIEEWDLVLAASAASTEVSILA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VVMALLPKKEEKHPEIFVNFMEPCYGSCTERQHHYYLSYIEEWDLVLAASAASTEVSILA
             320       330       340       350       360       370 

              340       350       360       370       380       390
pF1KSD RQSDQINWESWLLEDSSRAELPVTDKSDDSLPMGVVVDYTNQVEITISDEKTLPPAPVLM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RQSDQINWESWLLEDSSRAELPVTDKSDDSLPMGVVVDYTNQVEITISDEKTLPPAPVLM
             380       390       400       410       420       430 

              400       410       420       430       440       450
pF1KSD LLSTDGVLCPFYMINQNPGVKSLIKTPERLSLEGERQPKSPGSTPTTPTSSQAPQKLDAS
       :::::::::::::::::::::::::::::::::::::::::                   
XP_005 LLSTDGVLCPFYMINQNPGVKSLIKTPERLSLEGERQPKSP-------------------
             440       450       460       470                     

              460       470       480       490       500       510
pF1KSD AAAAPASLPPSSPAAPIATFSLLPAGGAPTVFSFGSSSLKSSATVTGEPPSYSSGSDSSK
                                                                   
XP_005 ------------------------------------------------------------
                                                                   

              520       530       540       550       560       570
pF1KSD AAPGPGPSTFSFVPPSKASLAPTPAASPVAPSAASFSFGSSGFKPTLESTPVPSVSAPNI
                        :::::::::::::::::::::::::::::::::::::::::::
XP_005 -----------------ASLAPTPAASPVAPSAASFSFGSSGFKPTLESTPVPSVSAPNI
                             480       490       500       510     

              580                  590       600       610         
pF1KSD AMKPSFPPSTSAVKVNLSE-----------NSSQSAPPMSPFSSASKPAASGPLSHPTPL
       :::::::::::::::::::           .:::::::::::::::::::::::::::::
XP_005 AMKPSFPPSTSAVKVNLSEKFTAAATSTPVSSSQSAPPMSPFSSASKPAASGPLSHPTPL
         520       530       540       550       560       570     

     620       630        640       650       660       670        
pF1KSD SAPPSSVPLKSSVLPSPS-GRSAQGSSSPVPSMVQKSPRITPPAAKPGSPQAKSLQPAVA
       :::::::::::::::::: :::::::::::::::::::::::::::::::::::::::::
XP_005 SAPPSSVPLKSSVLPSPSAGRSAQGSSSPVPSMVQKSPRITPPAAKPGSPQAKSLQPAVA
         580       590       600       610       620       630     

      680       690       700       710       720       730        
pF1KSD EKQGHQWKDSDPVMAGIGEEIAHFQKELEELKARTSKACFQVGTSEEMKMLRTESDDLHT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EKQGHQWKDSDPVMAGIGEEIAHFQKELEELKARTSKACFQVGTSEEMKMLRTESDDLHT
         640       650       660       670       680       690     

      740       750       760       770       780       790        
pF1KSD FLLEIKETTESLHGDISSLKTTLLEGFAGVEEAREQNERNRDSGYLHLLYKRPLDPKSEA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 FLLEIKETTESLHGDISSLKTTLLEGFAGVEEAREQNERNRDSGYLHLLYKRPLDPKSEA
         700       710       720       730       740       750     

      800       810       820       830       840       850        
pF1KSD QLQEIRRLHQYVKFAVQDVNDVLDLEWDQHLEQKKKQRHLLVPERETLFNTLANNREIIN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QLQEIRRLHQYVKFAVQDVNDVLDLEWDQHLEQKKKQRHLLVPERETLFNTLANNREIIN
         760       770       780       790       800       810     

      860       870       880       890       900       910        
pF1KSD QQRKRLNHLVDSLQQLRLYKQTSLWSLSSAVPSQSSIHSFDSDLESLCNALLKTTIESHT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QQRKRLNHLVDSLQQLRLYKQTSLWSLSSAVPSQSSIHSFDSDLESLCNALLKTTIESHT
         820       830       840       850       860       870     

      920       930       940       950       960       970        
pF1KSD KSLPKVPAKLSPMKQAQLRNFLAKRKTPPVRSTAPASLSRSAFLSQRYYEDLDEVSSTSS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KSLPKVPAKLSPMKQAQLRNFLAKRKTPPVRSTAPASLSRSAFLSQRYYEDLDEVSSTSS
         880       890       900       910       920       930     

      980       990      1000      1010      1020      1030        
pF1KSD VSQSLESEDARTSCKDDEAVVQAPRHAPVVRTPSIQPSLLPHAAPFAKSHLVHGSSPGVM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VSQSLESEDARTSCKDDEAVVQAPRHAPVVRTPSIQPSLLPHAAPFAKSHLVHGSSPGVM
         940       950       960       970       980       990     

     1040      1050      1060      1070      1080      1090        
pF1KSD GTSVATSASKIIPQGADSTMLATKTVKHGAPSPSHPISAPQAAAAAALRRQMASQAPAVN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GTSVATSASKIIPQGADSTMLATKTVKHGAPSPSHPISAPQAAAAAALRRQMASQAPAVN
        1000      1010      1020      1030      1040      1050     

     1100      1110      1120                1130      1140        
pF1KSD TLTESTLKNVPQVVNVQELKNNPATPSTA----------KTPHPVLTPVAANQAKQGSLI
       :::::::::::::::::::::::::::::          :::::::::::::::::::::
XP_005 TLTESTLKNVPQVVNVQELKNNPATPSTAMGSSVPYSTAKTPHPVLTPVAANQAKQGSLI
        1060      1070      1080      1090      1100      1110     

     1150      1160      1170      1180      1190      1200        
pF1KSD NSLKPSGPTPASGQLSSGDKASGTAKIETAVTSTPSASGQFSKPFSFSPSGTGFNFGIIT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 NSLKPSGPTPASGQLSSGDKASGTAKIETAVTSTPSASGQFSKPFSFSPSGTGFNFGIIT
        1120      1130      1140      1150      1160      1170     

     1210      1220      1230      1240      1250      1260        
pF1KSD PTPSSNFTAAQGATPSTKESSQPDAFSSGGGSKPSYEAIPESSPPSGITSASNTTPGEPA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PTPSSNFTAAQGATPSTKESSQPDAFSSGGGSKPSYEAIPESSPPSGITSASNTTPGEPA
        1180      1190      1200      1210      1220      1230     

     1270      1280      1290      1300      1310      1320        
pF1KSD ASSSRPVAPSGTALSTTSSKLETPPSKLGELLFPSSLAGETLGSFSGLRVGQADDSTKPT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ASSSRPVAPSGTALSTTSSKLETPPSKLGELLFPSSLAGETLGSFSGLRVGQADDSTKPT
        1240      1250      1260      1270      1280      1290     

     1330      1340      1350      1360      1370      1380        
pF1KSD NKASSTSLTSTQPTKTSGVPSGFNFTAPPVLGKHTEPPVTSSATTTSVAPPAATSTSSTA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 NKASSTSLTSTQPTKTSGVPSGFNFTAPPVLGKHTEPPVTSSATTTSVAPPAATSTSSTA
        1300      1310      1320      1330      1340      1350     

     1390      1400      1410      1420      1430      1440        
pF1KSD VFGSLPVTSAGSSGVISFGGTSLSAGKTSFSFGSQQTNSTVPPSAPPPTTAATPLPTSFP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VFGSLPVTSAGSSGVISFGGTSLSAGKTSFSFGSQQTNSTVPPSAPPPTTAATPLPTSFP
        1360      1370      1380      1390      1400      1410     

     1450      1460      1470      1480      1490      1500        
pF1KSD TLSFGSLLSSATTPSLPMSAGRSTEEATSSALPEKPGDSEVSASAASLLEEQQSAQLPQA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TLSFGSLLSSATTPSLPMSAGRSTEEATSSALPEKPGDSEVSASAASLLEEQQSAQLPQA
        1420      1430      1440      1450      1460      1470     

     1510      1520      1530      1540      1550      1560        
pF1KSD PPQTSDSVKKEPVLAQPAVSNSGTAASSTSLVALSAEATPATTGVPDARTEAVPPASSFS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PPQTSDSVKKEPVLAQPAVSNSGTAASSTSLVALSAEATPATTGVPDARTEAVPPASSFS
        1480      1490      1500      1510      1520      1530     

     1570      1580      1590      1600      1610      1620        
pF1KSD VPGQTAVTAAAISSAGPVAVETSSTPIASSTTSIVAPGPSAEAAAFGTVTSGSSVFAQPP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VPGQTAVTAAAISSAGPVAVETSSTPIASSTTSIVAPGPSAEAAAFGTVTSGSSVFAQPP
        1540      1550      1560      1570      1580      1590     

     1630      1640      1650      1660      1670      1680        
pF1KSD AASSSSAFNQLTNNTATAPSATPVFGQVAASTAPSLFGQQTGSTASTAAATPQVSSSGFS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 AASSSSAFNQLTNNTATAPSATPVFGQVAASTAPSLFGQQTGSTASTAAATPQVSSSGFS
        1600      1610      1620      1630      1640      1650     

     1690      1700      1710      1720      1730      1740        
pF1KSD SPAFGTTAPGVFGQTTFGQASVFGQSASSAASVFSFSQPGFSSVPAFGQPASSTPTSTSG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SPAFGTTAPGVFGQTTFGQASVFGQSASSAASVFSFSQPGFSSVPAFGQPASSTPTSTSG
        1660      1670      1680      1690      1700      1710     

     1750      1760      1770      1780      1790      1800        
pF1KSD SVFGAASSTSSSSSFSFGQSSPNTGGGLFGQSNAPAFGQSPGFGQGGSVFGGTSAATTTA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SVFGAASSTSSSSSFSFGQSSPNTGGGLFGQSNAPAFGQSPGFGQGGSVFGGTSAATTTA
        1720      1730      1740      1750      1760      1770     

     1810      1820      1830      1840      1850      1860        
pF1KSD ATSGFSFCQASGFGSSNTGSVFGQAASTGGIVFGQQSSSSSGSVFGSGNTGRGGGFFSGL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ATSGFSFCQASGFGSSNTGSVFGQAASTGGIVFGQQSSSSSGSVFGSGNTGRGGGFFSGL
        1780      1790      1800      1810      1820      1830     

     1870      1880      1890      1900      1910      1920        
pF1KSD GGKPSQDAANKNPFSSASGGFGSTATSNTSNLFGNSGAKTFGGFASSSFGEQKPTGTFSS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GGKPSQDAANKNPFSSASGGFGSTATSNTSNLFGNSGAKTFGGFASSSFGEQKPTGTFSS
        1840      1850      1860      1870      1880      1890     

     1930      1940      1950      1960      1970      1980        
pF1KSD GGGSVASQGFGFSSPNKTGGFGAAPVFGSPPTFGGSPGFGGVPAFGSAPAFTSPLGSTGG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GGGSVASQGFGFSSPNKTGGFGAAPVFGSPPTFGGSPGFGGVPAFGSAPAFTSPLGSTGG
        1900      1910      1920      1930      1940      1950     

     1990      2000      2010      2020      2030      2040        
pF1KSD KVFGEGTAAASAGGFGSLAMSLSPTLKGRLLLMRPKAGGGREQAAPGRKSNESRSLGHLC
       :::::::::::::::: .. : . :  : :  .   . :.  : . :  .. :       
XP_005 KVFGEGTAAASAGGFG-FGSSSNTTSFGTLASQNAPTFGSLSQQTSGFGTQSSGFSGFGS
        1960      1970       1980      1990      2000      2010    

     2050      2060      2070      2080      2090   
pF1KSD MERALTSPLKVWEQQQHHILRHARESECPHFRITVPTDFWFWDPE
                                                    
XP_005 GTGGFSFGSNNSSVQGFGGWRS                       
         2020      2030                             

>>NP_001305254 (OMIM: 114350,613065) nuclear pore comple  (916 aa)
 initn: 5364 init1: 5301 opt: 5306  Z-score: 2006.5  bits: 383.7 E(85289): 5e-105
Smith-Waterman score: 5306; 96.7% identity (97.7% similar) in 871 aa overlap (1171-2041:18-887)

             1150      1160      1170      1180      1190      1200
pF1KSD QAKQGSLINSLKPSGPTPASGQLSSGDKASGTAKIETAVTSTPSASGQFSKPFSFSPSGT
                                     ::::::::::::::::::::::::::::::
NP_001              MKSSLLLRGVHFCFHLPGTAKIETAVTSTPSASGQFSKPFSFSPSGT
                            10        20        30        40       

             1210      1220      1230      1240      1250      1260
pF1KSD GFNFGIITPTPSSNFTAAQGATPSTKESSQPDAFSSGGGSKPSYEAIPESSPPSGITSAS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GFNFGIITPTPSSNFTAAQGATPSTKESSQPDAFSSGGGSKPSYEAIPESSPPSGITSAS
        50        60        70        80        90       100       

             1270      1280      1290      1300      1310      1320
pF1KSD NTTPGEPAASSSRPVAPSGTALSTTSSKLETPPSKLGELLFPSSLAGETLGSFSGLRVGQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NTTPGEPAASSSRPVAPSGTALSTTSSKLETPPSKLGELLFPSSLAGETLGSFSGLRVGQ
       110       120       130       140       150       160       

             1330      1340      1350      1360      1370      1380
pF1KSD ADDSTKPTNKASSTSLTSTQPTKTSGVPSGFNFTAPPVLGKHTEPPVTSSATTTSVAPPA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ADDSTKPTNKASSTSLTSTQPTKTSGVPSGFNFTAPPVLGKHTEPPVTSSATTTSVAPPA
       170       180       190       200       210       220       

             1390      1400      1410      1420      1430      1440
pF1KSD ATSTSSTAVFGSLPVTSAGSSGVISFGGTSLSAGKTSFSFGSQQTNSTVPPSAPPPTTAA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ATSTSSTAVFGSLPVTSAGSSGVISFGGTSLSAGKTSFSFGSQQTNSTVPPSAPPPTTAA
       230       240       250       260       270       280       

             1450      1460      1470      1480      1490      1500
pF1KSD TPLPTSFPTLSFGSLLSSATTPSLPMSAGRSTEEATSSALPEKPGDSEVSASAASLLEEQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TPLPTSFPTLSFGSLLSSATTPSLPMSAGRSTEEATSSALPEKPGDSEVSASAASLLEEQ
       290       300       310       320       330       340       

             1510      1520      1530      1540      1550      1560
pF1KSD QSAQLPQAPPQTSDSVKKEPVLAQPAVSNSGTAASSTSLVALSAEATPATTGVPDARTEA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QSAQLPQAPPQTSDSVKKEPVLAQPAVSNSGTAASSTSLVALSAEATPATTGVPDARTEA
       350       360       370       380       390       400       

             1570      1580      1590      1600      1610      1620
pF1KSD VPPASSFSVPGQTAVTAAAISSAGPVAVETSSTPIASSTTSIVAPGPSAEAAAFGTVTSG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VPPASSFSVPGQTAVTAAAISSAGPVAVETSSTPIASSTTSIVAPGPSAEAAAFGTVTSG
       410       420       430       440       450       460       

             1630      1640      1650      1660      1670      1680
pF1KSD SSVFAQPPAASSSSAFNQLTNNTATAPSATPVFGQVAASTAPSLFGQQTGSTASTAAATP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SSVFAQPPAASSSSAFNQLTNNTATAPSATPVFGQVAASTAPSLFGQQTGSTASTAAATP
       470       480       490       500       510       520       

             1690      1700      1710      1720      1730      1740
pF1KSD QVSSSGFSSPAFGTTAPGVFGQTTFGQASVFGQSASSAASVFSFSQPGFSSVPAFGQPAS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QVSSSGFSSPAFGTTAPGVFGQTTFGQASVFGQSASSAASVFSFSQPGFSSVPAFGQPAS
       530       540       550       560       570       580       

             1750      1760      1770      1780      1790      1800
pF1KSD STPTSTSGSVFGAASSTSSSSSFSFGQSSPNTGGGLFGQSNAPAFGQSPGFGQGGSVFGG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 STPTSTSGSVFGAASSTSSSSSFSFGQSSPNTGGGLFGQSNAPAFGQSPGFGQGGSVFGG
       590       600       610       620       630       640       

             1810      1820      1830      1840      1850      1860
pF1KSD TSAATTTAATSGFSFCQASGFGSSNTGSVFGQAASTGGIVFGQQSSSSSGSVFGSGNTGR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TSAATTTAATSGFSFCQASGFGSSNTGSVFGQAASTGGIVFGQQSSSSSGSVFGSGNTGR
       650       660       670       680       690       700       

             1870      1880      1890      1900      1910      1920
pF1KSD GGGFFSGLGGKPSQDAANKNPFSSASGGFGSTATSNTSNLFGNSGAKTFGGFASSSFGEQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GGGFFSGLGGKPSQDAANKNPFSSASGGFGSTATSNTSNLFGNSGAKTFGGFASSSFGEQ
       710       720       730       740       750       760       

             1930      1940      1950      1960      1970      1980
pF1KSD KPTGTFSSGGGSVASQGFGFSSPNKTGGFGAAPVFGSPPTFGGSPGFGGVPAFGSAPAFT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KPTGTFSSGGGSVASQGFGFSSPNKTGGFGAAPVFGSPPTFGGSPGFGGVPAFGSAPAFT
       770       780       790       800       810       820       

             1990      2000      2010      2020      2030      2040
pF1KSD SPLGSTGGKVFGEGTAAASAGGFGSLAMSLSPTLKGRLLLMRPKAGGGREQAAPGRKSNE
       :::::::::::::::::::::::: .. : . :  : :  .   . :.  : . :  .. 
NP_001 SPLGSTGGKVFGEGTAAASAGGFG-FGSSSNTTSFGTLASQNAPTFGSLSQQTSGFGTQS
       830       840       850        860       870       880      

             2050      2060      2070      2080      2090   
pF1KSD SRSLGHLCMERALTSPLKVWEQQQHHILRHARESECPHFRITVPTDFWFWDPE
       :                                                    
NP_001 SGFSGFGSGTGGFSFGSNNSSVQGFGGWRS                       
        890       900       910                             

>>XP_005272275 (OMIM: 114350,613065) PREDICTED: nuclear   (2083 aa)
 initn: 8986 init1: 4992 opt: 5189  Z-score: 1957.6  bits: 375.9 E(85289): 2.7e-102
Smith-Waterman score: 12445; 95.1% identity (95.6% similar) in 2063 aa overlap (1-2041:42-2054)

                                             10        20        30
pF1KSD                               MGDEMDAMIPEREMKDFQFRALKKVRIFDS
                                     ::::::::::::::::::::::::::::::
XP_005 GRKFAVERPGFRGQGRGRQRWLLRHTEGGAMGDEMDAMIPEREMKDFQFRALKKVRIFDS
              20        30        40        50        60        70 

               40        50        60        70        80        90
pF1KSD PEELPKERSSLLAVSNKYGLVFAGGASGLQIFPTKNLLIQNKPGDDPNKIVDKVQGLLVP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PEELPKERSSLLAVSNKYGLVFAGGASGLQIFPTKNLLIQNKPGDDPNKIVDKVQGLLVP
              80        90       100       110       120       130 

              100       110       120       130       140       150
pF1KSD MKFPIHHLALSCDNLTLSACMMSSEYGSIIAFFDVRTFSNEAKQQKRPFAYHKLLKDAGG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MKFPIHHLALSCDNLTLSACMMSSEYGSIIAFFDVRTFSNEAKQQKRPFAYHKLLKDAGG
             140       150       160       170       180       190 

              160       170       180       190       200       210
pF1KSD MVIDMKWNPTVPSMVAVCLADGSIAVLQVTETVKVCATLPSTVAVTSVCWSPKGKQLAVG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MVIDMKWNPTVPSMVAVCLADGSIAVLQVTETVKVCATLPSTVAVTSVCWSPKGKQLAVG
             200       210       220       230       240       250 

              220       230       240       250       260       270
pF1KSD KQNGTVVQYLPTLQEKKVIPCPPFYESDHPVRVLDVLWIGTYVFAIVYAAADGTLETSPD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KQNGTVVQYLPTLQEKKVIPCPPFYESDHPVRVLDVLWIGTYVFAIVYAAADGTLETSPD
             260       270       280       290       300       310 

              280       290       300       310       320       330
pF1KSD VVMALLPKKEEKHPEIFVNFMEPCYGSCTERQHHYYLSYIEEWDLVLAASAASTEVSILA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VVMALLPKKEEKHPEIFVNFMEPCYGSCTERQHHYYLSYIEEWDLVLAASAASTEVSILA
             320       330       340       350       360       370 

              340       350       360       370       380       390
pF1KSD RQSDQINWESWLLEDSSRAELPVTDKSDDSLPMGVVVDYTNQVEITISDEKTLPPAPVLM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RQSDQINWESWLLEDSSRAELPVTDKSDDSLPMGVVVDYTNQVEITISDEKTLPPAPVLM
             380       390       400       410       420       430 

              400       410       420       430       440       450
pF1KSD LLSTDGVLCPFYMINQNPGVKSLIKTPERLSLEGERQPKSPGSTPTTPTSSQAPQKLDAS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LLSTDGVLCPFYMINQNPGVKSLIKTPERLSLEGERQPKSPGSTPTTPTSSQAPQKLDAS
             440       450       460       470       480       490 

              460       470       480       490       500       510
pF1KSD AAAAPASLPPSSPAAPIATFSLLPAGGAPTVFSFGSSSLKSSATVTGEPPSYSSGSDSSK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 AAAAPASLPPSSPAAPIATFSLLPAGGAPTVFSFGSSSLKSSATVTGEPPSYSSGSDSSK
             500       510       520       530       540       550 

              520       530       540       550       560       570
pF1KSD AAPGPGPSTFSFVPPSKASLAPTPAASPVAPSAASFSFGSSGFKPTLESTPVPSVSAPNI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 AAPGPGPSTFSFVPPSKASLAPTPAASPVAPSAASFSFGSSGFKPTLESTPVPSVSAPNI
             560       570       580       590       600       610 

              580                  590       600       610         
pF1KSD AMKPSFPPSTSAVKVNLSE-----------NSSQSAPPMSPFSSASKPAASGPLSHPTPL
       :::::::::::::::::::           .:::::::::::::::::::::::::::::
XP_005 AMKPSFPPSTSAVKVNLSEKFTAAATSTPVSSSQSAPPMSPFSSASKPAASGPLSHPTPL
             620       630       640       650       660       670 

     620       630        640       650       660       670        
pF1KSD SAPPSSVPLKSSVLPSPS-GRSAQGSSSPVPSMVQKSPRITPPAAKPGSPQAKSLQPAVA
       :::::::::::::::::: :::::::::::::::::::::::::::::::::::::::::
XP_005 SAPPSSVPLKSSVLPSPSAGRSAQGSSSPVPSMVQKSPRITPPAAKPGSPQAKSLQPAVA
             680       690       700       710       720       730 

      680       690       700       710       720       730        
pF1KSD EKQGHQWKDSDPVMAGIGEEIAHFQKELEELKARTSKACFQVGTSEEMKMLRTESDDLHT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EKQGHQWKDSDPVMAGIGEEIAHFQKELEELKARTSKACFQVGTSEEMKMLRTESDDLHT
             740       750       760       770       780       790 

      740       750       760       770       780       790        
pF1KSD FLLEIKETTESLHGDISSLKTTLLEGFAGVEEAREQNERNRDSGYLHLLYKRPLDPKSEA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 FLLEIKETTESLHGDISSLKTTLLEGFAGVEEAREQNERNRDSGYLHLLYKRPLDPKSEA
             800       810       820       830       840       850 

      800       810       820       830       840       850        
pF1KSD QLQEIRRLHQYVKFAVQDVNDVLDLEWDQHLEQKKKQRHLLVPERETLFNTLANNREIIN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QLQEIRRLHQYVKFAVQDVNDVLDLEWDQHLEQKKKQRHLLVPERETLFNTLANNREIIN
             860       870       880       890       900       910 

      860       870       880       890       900       910        
pF1KSD QQRKRLNHLVDSLQQLRLYKQTSLWSLSSAVPSQSSIHSFDSDLESLCNALLKTTIESHT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QQRKRLNHLVDSLQQLRLYKQTSLWSLSSAVPSQSSIHSFDSDLESLCNALLKTTIESHT
             920       930       940       950       960       970 

      920       930       940       950       960       970        
pF1KSD KSLPKVPAKLSPMKQAQLRNFLAKRKTPPVRSTAPASLSRSAFLSQRYYEDLDEVSSTSS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KSLPKVPAKLSPMKQAQLRNFLAKRKTPPVRSTAPASLSRSAFLSQRYYEDLDEVSSTSS
             980       990      1000      1010      1020      1030 

      980       990      1000      1010      1020      1030        
pF1KSD VSQSLESEDARTSCKDDEAVVQAPRHAPVVRTPSIQPSLLPHAAPFAKSHLVHGSSPGVM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VSQSLESEDARTSCKDDEAVVQAPRHAPVVRTPSIQPSLLPHAAPFAKSHLVHGSSPGVM
            1040      1050      1060      1070      1080      1090 

     1040      1050      1060      1070      1080      1090        
pF1KSD GTSVATSASKIIPQGADSTMLATKTVKHGAPSPSHPISAPQAAAAAALRRQMASQAPAVN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GTSVATSASKIIPQGADSTMLATKTVKHGAPSPSHPISAPQAAAAAALRRQMASQAPAVN
            1100      1110      1120      1130      1140      1150 

     1100      1110      1120                1130      1140        
pF1KSD TLTESTLKNVPQVVNVQELKNNPATPSTA----------KTPHPVLTPVAANQAKQGSLI
       :::::::::::::::::::::::::::::          :::::::::::::::::::::
XP_005 TLTESTLKNVPQVVNVQELKNNPATPSTAMGSSVPYSTAKTPHPVLTPVAANQAKQGSLI
            1160      1170      1180      1190      1200      1210 

     1150      1160      1170      1180      1190      1200        
pF1KSD NSLKPSGPTPASGQLSSGDKASGTAKIETAVTSTPSASGQFSKPFSFSPSGTGFNFGIIT
       :::::::::::::::::::::::                                     
XP_005 NSLKPSGPTPASGQLSSGDKASG-------------------------------------
            1220      1230                                         

     1210      1220      1230      1240      1250      1260        
pF1KSD PTPSSNFTAAQGATPSTKESSQPDAFSSGGGSKPSYEAIPESSPPSGITSASNTTPGEPA
                   ::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ------------ATPSTKESSQPDAFSSGGGSKPSYEAIPESSPPSGITSASNTTPGEPA
                     1240      1250      1260      1270      1280  

     1270      1280      1290      1300      1310      1320        
pF1KSD ASSSRPVAPSGTALSTTSSKLETPPSKLGELLFPSSLAGETLGSFSGLRVGQADDSTKPT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ASSSRPVAPSGTALSTTSSKLETPPSKLGELLFPSSLAGETLGSFSGLRVGQADDSTKPT
           1290      1300      1310      1320      1330      1340  

     1330      1340      1350      1360      1370      1380        
pF1KSD NKASSTSLTSTQPTKTSGVPSGFNFTAPPVLGKHTEPPVTSSATTTSVAPPAATSTSSTA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 NKASSTSLTSTQPTKTSGVPSGFNFTAPPVLGKHTEPPVTSSATTTSVAPPAATSTSSTA
           1350      1360      1370      1380      1390      1400  

     1390      1400      1410      1420      1430      1440        
pF1KSD VFGSLPVTSAGSSGVISFGGTSLSAGKTSFSFGSQQTNSTVPPSAPPPTTAATPLPTSFP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VFGSLPVTSAGSSGVISFGGTSLSAGKTSFSFGSQQTNSTVPPSAPPPTTAATPLPTSFP
           1410      1420      1430      1440      1450      1460  

     1450      1460      1470      1480      1490      1500        
pF1KSD TLSFGSLLSSATTPSLPMSAGRSTEEATSSALPEKPGDSEVSASAASLLEEQQSAQLPQA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TLSFGSLLSSATTPSLPMSAGRSTEEATSSALPEKPGDSEVSASAASLLEEQQSAQLPQA
           1470      1480      1490      1500      1510      1520  

     1510      1520      1530      1540      1550      1560        
pF1KSD PPQTSDSVKKEPVLAQPAVSNSGTAASSTSLVALSAEATPATTGVPDARTEAVPPASSFS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PPQTSDSVKKEPVLAQPAVSNSGTAASSTSLVALSAEATPATTGVPDARTEAVPPASSFS
           1530      1540      1550      1560      1570      1580  

     1570      1580      1590      1600      1610      1620        
pF1KSD VPGQTAVTAAAISSAGPVAVETSSTPIASSTTSIVAPGPSAEAAAFGTVTSGSSVFAQPP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VPGQTAVTAAAISSAGPVAVETSSTPIASSTTSIVAPGPSAEAAAFGTVTSGSSVFAQPP
           1590      1600      1610      1620      1630      1640  

     1630      1640      1650      1660      1670      1680        
pF1KSD AASSSSAFNQLTNNTATAPSATPVFGQVAASTAPSLFGQQTGSTASTAAATPQVSSSGFS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 AASSSSAFNQLTNNTATAPSATPVFGQVAASTAPSLFGQQTGSTASTAAATPQVSSSGFS
           1650      1660      1670      1680      1690      1700  

     1690      1700      1710      1720      1730      1740        
pF1KSD SPAFGTTAPGVFGQTTFGQASVFGQSASSAASVFSFSQPGFSSVPAFGQPASSTPTSTSG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SPAFGTTAPGVFGQTTFGQASVFGQSASSAASVFSFSQPGFSSVPAFGQPASSTPTSTSG
           1710      1720      1730      1740      1750      1760  

     1750      1760      1770      1780      1790      1800        
pF1KSD SVFGAASSTSSSSSFSFGQSSPNTGGGLFGQSNAPAFGQSPGFGQGGSVFGGTSAATTTA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SVFGAASSTSSSSSFSFGQSSPNTGGGLFGQSNAPAFGQSPGFGQGGSVFGGTSAATTTA
           1770      1780      1790      1800      1810      1820  

     1810      1820      1830      1840      1850      1860        
pF1KSD ATSGFSFCQASGFGSSNTGSVFGQAASTGGIVFGQQSSSSSGSVFGSGNTGRGGGFFSGL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ATSGFSFCQASGFGSSNTGSVFGQAASTGGIVFGQQSSSSSGSVFGSGNTGRGGGFFSGL
           1830      1840      1850      1860      1870      1880  

     1870      1880      1890      1900      1910      1920        
pF1KSD GGKPSQDAANKNPFSSASGGFGSTATSNTSNLFGNSGAKTFGGFASSSFGEQKPTGTFSS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GGKPSQDAANKNPFSSASGGFGSTATSNTSNLFGNSGAKTFGGFASSSFGEQKPTGTFSS
           1890      1900      1910      1920      1930      1940  

     1930      1940      1950      1960      1970      1980        
pF1KSD GGGSVASQGFGFSSPNKTGGFGAAPVFGSPPTFGGSPGFGGVPAFGSAPAFTSPLGSTGG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GGGSVASQGFGFSSPNKTGGFGAAPVFGSPPTFGGSPGFGGVPAFGSAPAFTSPLGSTGG
           1950      1960      1970      1980      1990      2000  

     1990      2000      2010      2020      2030      2040        
pF1KSD KVFGEGTAAASAGGFGSLAMSLSPTLKGRLLLMRPKAGGGREQAAPGRKSNESRSLGHLC
       :::::::::::::::: .. : . :  : :  .   . :.  : . :  .. :       
XP_005 KVFGEGTAAASAGGFG-FGSSSNTTSFGTLASQNAPTFGSLSQQTSGFGTQSSGFSGFGS
           2010       2020      2030      2040      2050      2060 

     2050      2060      2070      2080      2090   
pF1KSD MERALTSPLKVWEQQQHHILRHARESECPHFRITVPTDFWFWDPE
                                                    
XP_005 GTGGFSFGSNNSSVQGFGGWRS                       
            2070      2080                          

>>XP_011517357 (OMIM: 114350,613065) PREDICTED: nuclear   (1908 aa)
 initn: 8445 init1: 4514 opt: 4833  Z-score: 1825.2  bits: 351.2 E(85289): 6.3e-95
Smith-Waterman score: 11781; 98.8% identity (98.8% similar) in 1865 aa overlap (1-1843:42-1906)

                                             10        20        30
pF1KSD                               MGDEMDAMIPEREMKDFQFRALKKVRIFDS
                                     ::::::::::::::::::::::::::::::
XP_011 GRKFAVERPGFRGQGRGRQRWLLRHTEGGAMGDEMDAMIPEREMKDFQFRALKKVRIFDS
              20        30        40        50        60        70 

               40        50        60        70        80        90
pF1KSD PEELPKERSSLLAVSNKYGLVFAGGASGLQIFPTKNLLIQNKPGDDPNKIVDKVQGLLVP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PEELPKERSSLLAVSNKYGLVFAGGASGLQIFPTKNLLIQNKPGDDPNKIVDKVQGLLVP
              80        90       100       110       120       130 

              100       110       120       130       140       150
pF1KSD MKFPIHHLALSCDNLTLSACMMSSEYGSIIAFFDVRTFSNEAKQQKRPFAYHKLLKDAGG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MKFPIHHLALSCDNLTLSACMMSSEYGSIIAFFDVRTFSNEAKQQKRPFAYHKLLKDAGG
             140       150       160       170       180       190 

              160       170       180       190       200       210
pF1KSD MVIDMKWNPTVPSMVAVCLADGSIAVLQVTETVKVCATLPSTVAVTSVCWSPKGKQLAVG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MVIDMKWNPTVPSMVAVCLADGSIAVLQVTETVKVCATLPSTVAVTSVCWSPKGKQLAVG
             200       210       220       230       240       250 

              220       230       240       250       260       270
pF1KSD KQNGTVVQYLPTLQEKKVIPCPPFYESDHPVRVLDVLWIGTYVFAIVYAAADGTLETSPD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KQNGTVVQYLPTLQEKKVIPCPPFYESDHPVRVLDVLWIGTYVFAIVYAAADGTLETSPD
             260       270       280       290       300       310 

              280       290       300       310       320       330
pF1KSD VVMALLPKKEEKHPEIFVNFMEPCYGSCTERQHHYYLSYIEEWDLVLAASAASTEVSILA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VVMALLPKKEEKHPEIFVNFMEPCYGSCTERQHHYYLSYIEEWDLVLAASAASTEVSILA
             320       330       340       350       360       370 

              340       350       360       370       380       390
pF1KSD RQSDQINWESWLLEDSSRAELPVTDKSDDSLPMGVVVDYTNQVEITISDEKTLPPAPVLM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RQSDQINWESWLLEDSSRAELPVTDKSDDSLPMGVVVDYTNQVEITISDEKTLPPAPVLM
             380       390       400       410       420       430 

              400       410       420       430       440       450
pF1KSD LLSTDGVLCPFYMINQNPGVKSLIKTPERLSLEGERQPKSPGSTPTTPTSSQAPQKLDAS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LLSTDGVLCPFYMINQNPGVKSLIKTPERLSLEGERQPKSPGSTPTTPTSSQAPQKLDAS
             440       450       460       470       480       490 

              460       470       480       490       500       510
pF1KSD AAAAPASLPPSSPAAPIATFSLLPAGGAPTVFSFGSSSLKSSATVTGEPPSYSSGSDSSK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AAAAPASLPPSSPAAPIATFSLLPAGGAPTVFSFGSSSLKSSATVTGEPPSYSSGSDSSK
             500       510       520       530       540       550 

              520       530       540       550       560       570
pF1KSD AAPGPGPSTFSFVPPSKASLAPTPAASPVAPSAASFSFGSSGFKPTLESTPVPSVSAPNI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AAPGPGPSTFSFVPPSKASLAPTPAASPVAPSAASFSFGSSGFKPTLESTPVPSVSAPNI
             560       570       580       590       600       610 

              580                  590       600       610         
pF1KSD AMKPSFPPSTSAVKVNLSE-----------NSSQSAPPMSPFSSASKPAASGPLSHPTPL
       :::::::::::::::::::           .:::::::::::::::::::::::::::::
XP_011 AMKPSFPPSTSAVKVNLSEKFTAAATSTPVSSSQSAPPMSPFSSASKPAASGPLSHPTPL
             620       630       640       650       660       670 

     620       630        640       650       660       670        
pF1KSD SAPPSSVPLKSSVLPSPS-GRSAQGSSSPVPSMVQKSPRITPPAAKPGSPQAKSLQPAVA
       :::::::::::::::::: :::::::::::::::::::::::::::::::::::::::::
XP_011 SAPPSSVPLKSSVLPSPSAGRSAQGSSSPVPSMVQKSPRITPPAAKPGSPQAKSLQPAVA
             680       690       700       710       720       730 

      680       690       700       710       720       730        
pF1KSD EKQGHQWKDSDPVMAGIGEEIAHFQKELEELKARTSKACFQVGTSEEMKMLRTESDDLHT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EKQGHQWKDSDPVMAGIGEEIAHFQKELEELKARTSKACFQVGTSEEMKMLRTESDDLHT
             740       750       760       770       780       790 

      740       750       760       770       780       790        
pF1KSD FLLEIKETTESLHGDISSLKTTLLEGFAGVEEAREQNERNRDSGYLHLLYKRPLDPKSEA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FLLEIKETTESLHGDISSLKTTLLEGFAGVEEAREQNERNRDSGYLHLLYKRPLDPKSEA
             800       810       820       830       840       850 

      800       810       820       830       840       850        
pF1KSD QLQEIRRLHQYVKFAVQDVNDVLDLEWDQHLEQKKKQRHLLVPERETLFNTLANNREIIN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QLQEIRRLHQYVKFAVQDVNDVLDLEWDQHLEQKKKQRHLLVPERETLFNTLANNREIIN
             860       870       880       890       900       910 

      860       870       880       890       900       910        
pF1KSD QQRKRLNHLVDSLQQLRLYKQTSLWSLSSAVPSQSSIHSFDSDLESLCNALLKTTIESHT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QQRKRLNHLVDSLQQLRLYKQTSLWSLSSAVPSQSSIHSFDSDLESLCNALLKTTIESHT
             920       930       940       950       960       970 

      920       930       940       950       960       970        
pF1KSD KSLPKVPAKLSPMKQAQLRNFLAKRKTPPVRSTAPASLSRSAFLSQRYYEDLDEVSSTSS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KSLPKVPAKLSPMKQAQLRNFLAKRKTPPVRSTAPASLSRSAFLSQRYYEDLDEVSSTSS
             980       990      1000      1010      1020      1030 

      980       990      1000      1010      1020      1030        
pF1KSD VSQSLESEDARTSCKDDEAVVQAPRHAPVVRTPSIQPSLLPHAAPFAKSHLVHGSSPGVM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VSQSLESEDARTSCKDDEAVVQAPRHAPVVRTPSIQPSLLPHAAPFAKSHLVHGSSPGVM
            1040      1050      1060      1070      1080      1090 

     1040      1050      1060      1070      1080      1090        
pF1KSD GTSVATSASKIIPQGADSTMLATKTVKHGAPSPSHPISAPQAAAAAALRRQMASQAPAVN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GTSVATSASKIIPQGADSTMLATKTVKHGAPSPSHPISAPQAAAAAALRRQMASQAPAVN
            1100      1110      1120      1130      1140      1150 

     1100      1110      1120                1130      1140        
pF1KSD TLTESTLKNVPQVVNVQELKNNPATPSTA----------KTPHPVLTPVAANQAKQGSLI
       :::::::::::::::::::::::::::::          :::::::::::::::::::::
XP_011 TLTESTLKNVPQVVNVQELKNNPATPSTAMGSSVPYSTAKTPHPVLTPVAANQAKQGSLI
            1160      1170      1180      1190      1200      1210 

     1150      1160      1170      1180      1190      1200        
pF1KSD NSLKPSGPTPASGQLSSGDKASGTAKIETAVTSTPSASGQFSKPFSFSPSGTGFNFGIIT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NSLKPSGPTPASGQLSSGDKASGTAKIETAVTSTPSASGQFSKPFSFSPSGTGFNFGIIT
            1220      1230      1240      1250      1260      1270 

     1210      1220      1230      1240      1250      1260        
pF1KSD PTPSSNFTAAQGATPSTKESSQPDAFSSGGGSKPSYEAIPESSPPSGITSASNTTPGEPA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PTPSSNFTAAQGATPSTKESSQPDAFSSGGGSKPSYEAIPESSPPSGITSASNTTPGEPA
            1280      1290      1300      1310      1320      1330 

     1270      1280      1290      1300      1310      1320        
pF1KSD ASSSRPVAPSGTALSTTSSKLETPPSKLGELLFPSSLAGETLGSFSGLRVGQADDSTKPT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ASSSRPVAPSGTALSTTSSKLETPPSKLGELLFPSSLAGETLGSFSGLRVGQADDSTKPT
            1340      1350      1360      1370      1380      1390 

     1330      1340      1350      1360      1370      1380        
pF1KSD NKASSTSLTSTQPTKTSGVPSGFNFTAPPVLGKHTEPPVTSSATTTSVAPPAATSTSSTA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NKASSTSLTSTQPTKTSGVPSGFNFTAPPVLGKHTEPPVTSSATTTSVAPPAATSTSSTA
            1400      1410      1420      1430      1440      1450 

     1390      1400      1410      1420      1430      1440        
pF1KSD VFGSLPVTSAGSSGVISFGGTSLSAGKTSFSFGSQQTNSTVPPSAPPPTTAATPLPTSFP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VFGSLPVTSAGSSGVISFGGTSLSAGKTSFSFGSQQTNSTVPPSAPPPTTAATPLPTSFP
            1460      1470      1480      1490      1500      1510 

     1450      1460      1470      1480      1490      1500        
pF1KSD TLSFGSLLSSATTPSLPMSAGRSTEEATSSALPEKPGDSEVSASAASLLEEQQSAQLPQA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TLSFGSLLSSATTPSLPMSAGRSTEEATSSALPEKPGDSEVSASAASLLEEQQSAQLPQA
            1520      1530      1540      1550      1560      1570 

     1510      1520      1530      1540      1550      1560        
pF1KSD PPQTSDSVKKEPVLAQPAVSNSGTAASSTSLVALSAEATPATTGVPDARTEAVPPASSFS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PPQTSDSVKKEPVLAQPAVSNSGTAASSTSLVALSAEATPATTGVPDARTEAVPPASSFS
            1580      1590      1600      1610      1620      1630 

     1570      1580      1590      1600      1610      1620        
pF1KSD VPGQTAVTAAAISSAGPVAVETSSTPIASSTTSIVAPGPSAEAAAFGTVTSGSSVFAQPP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VPGQTAVTAAAISSAGPVAVETSSTPIASSTTSIVAPGPSAEAAAFGTVTSGSSVFAQPP
            1640      1650      1660      1670      1680      1690 

     1630      1640      1650      1660      1670      1680        
pF1KSD AASSSSAFNQLTNNTATAPSATPVFGQVAASTAPSLFGQQTGSTASTAAATPQVSSSGFS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AASSSSAFNQLTNNTATAPSATPVFGQVAASTAPSLFGQQTGSTASTAAATPQVSSSGFS
            1700      1710      1720      1730      1740      1750 

     1690      1700      1710      1720      1730      1740        
pF1KSD SPAFGTTAPGVFGQTTFGQASVFGQSASSAASVFSFSQPGFSSVPAFGQPASSTPTSTSG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SPAFGTTAPGVFGQTTFGQASVFGQSASSAASVFSFSQPGFSSVPAFGQPASSTPTSTSG
            1760      1770      1780      1790      1800      1810 

     1750      1760      1770      1780      1790      1800        
pF1KSD SVFGAASSTSSSSSFSFGQSSPNTGGGLFGQSNAPAFGQSPGFGQGGSVFGGTSAATTTA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SVFGAASSTSSSSSFSFGQSSPNTGGGLFGQSNAPAFGQSPGFGQGGSVFGGTSAATTTA
            1820      1830      1840      1850      1860      1870 

     1810      1820      1830      1840      1850      1860        
pF1KSD ATSGFSFCQASGFGSSNTGSVFGQAASTGGIVFGQQSSSSSGSVFGSGNTGRGGGFFSGL
       :::::::::::::::::::::::::::::::::::                         
XP_011 ATSGFSFCQASGFGSSNTGSVFGQAASTGGIVFGQYL                       
            1880      1890      1900                               

     1870      1880      1890      1900      1910      1920        
pF1KSD GGKPSQDAANKNPFSSASGGFGSTATSNTSNLFGNSGAKTFGGFASSSFGEQKPTGTFSS




2093 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Wed Nov  2 23:24:28 2016 done: Wed Nov  2 23:24:31 2016
 Total Scan time: 19.780 Total Display time:  1.500

Function used was FASTA [36.3.4 Apr, 2011]
Inquiries or Suggestions ?
Send a message to flexiclone AT kazusagt.com