Result of FASTA (omim) for pF1KB0065
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB0065, 2041 aa
  1>>>pF1KB0065 2041 - 2041 aa - 2041 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 8.0218+/-0.000577; mu= 12.6256+/- 0.036
 mean_var=215.8247+/-47.105, 0's: 0 Z-trim(113.8): 379  B-trim: 1031 in 2/49
 Lambda= 0.087302
 statistics sampled from 22858 (23338) to 22858 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.598), E-opt: 0.2 (0.274), width:  16
 Scan time: 21.150

The best scores are:                                      opt bits E(85289)
XP_006716951 (OMIM: 603785,615219) PREDICTED: mult (2041) 13162 1673.2       0
NP_003820 (OMIM: 603785,615219) multiple PDZ domai (2041) 13162 1673.2       0
XP_016870741 (OMIM: 603785,615219) PREDICTED: mult (2042) 12155 1546.3       0
XP_006716950 (OMIM: 603785,615219) PREDICTED: mult (2070) 11606 1477.2       0
XP_006716948 (OMIM: 603785,615219) PREDICTED: mult (2070) 11606 1477.2       0
XP_006716949 (OMIM: 603785,615219) PREDICTED: mult (2070) 11606 1477.2       0
NP_001317566 (OMIM: 603785,615219) multiple PDZ do (2070) 11606 1477.2       0
XP_016870747 (OMIM: 603785,615219) PREDICTED: mult (1461) 9478 1209.0       0
NP_001248335 (OMIM: 603785,615219) multiple PDZ do (2037) 9434 1203.6       0
XP_006716952 (OMIM: 603785,615219) PREDICTED: mult (2037) 9434 1203.6       0
XP_016870742 (OMIM: 603785,615219) PREDICTED: mult (2008) 8061 1030.7       0
XP_006716954 (OMIM: 603785,615219) PREDICTED: mult (2008) 8061 1030.7       0
NP_001248336 (OMIM: 603785,615219) multiple PDZ do (2008) 8061 1030.7       0
XP_016870745 (OMIM: 603785,615219) PREDICTED: mult (1971) 7812 999.3       0
XP_016870746 (OMIM: 603785,615219) PREDICTED: mult (1971) 7812 999.3       0
XP_016870744 (OMIM: 603785,615219) PREDICTED: mult (2000) 7812 999.3       0
XP_005251680 (OMIM: 603785,615219) PREDICTED: mult (2000) 7812 999.3       0
XP_016870743 (OMIM: 603785,615219) PREDICTED: mult (2000) 7812 999.3       0
XP_016870748 (OMIM: 603785,615219) PREDICTED: mult (1167) 7205 922.6       0
XP_011538772 (OMIM: 603199) PREDICTED: inaD-like p ( 954) 1538 208.8 2.3e-52
XP_011538768 (OMIM: 603199) PREDICTED: inaD-like p (1907)  937 133.4 2.3e-29
NP_795352 (OMIM: 603199) inaD-like protein [Homo s (1801)  926 132.0 5.8e-29
XP_005270398 (OMIM: 603199) PREDICTED: inaD-like p (1882)  926 132.0   6e-29
XP_016855490 (OMIM: 603199) PREDICTED: inaD-like p ( 992)  746 109.0 2.6e-22
XP_016855489 (OMIM: 603199) PREDICTED: inaD-like p (1634)  746 109.3 3.6e-22
XP_011538769 (OMIM: 603199) PREDICTED: inaD-like p (1856)  746 109.3   4e-22
XP_011538764 (OMIM: 603199) PREDICTED: inaD-like p (1937)  746 109.3 4.1e-22
XP_011538765 (OMIM: 603199) PREDICTED: inaD-like p (1937)  746 109.3 4.1e-22
XP_011538766 (OMIM: 603199) PREDICTED: inaD-like p (1921)  726 106.8 2.3e-21
XP_011538767 (OMIM: 603199) PREDICTED: inaD-like p (1912)  721 106.2 3.6e-21
XP_011538770 (OMIM: 603199) PREDICTED: inaD-like p (1515)  606 91.6   7e-17
XP_016855488 (OMIM: 603199) PREDICTED: inaD-like p (1854)  606 91.7 8.1e-17
XP_016855487 (OMIM: 603199) PREDICTED: inaD-like p (1879)  606 91.7 8.2e-17
XP_006710341 (OMIM: 603199) PREDICTED: inaD-like p (1296)  551 84.6 7.7e-15
XP_005270404 (OMIM: 603199) PREDICTED: inaD-like p (1300)  551 84.6 7.7e-15
XP_011538771 (OMIM: 603199) PREDICTED: inaD-like p (1344)  551 84.6 7.9e-15
XP_011533297 (OMIM: 609733) PREDICTED: ligand of N ( 567)  421 67.9 3.7e-10
NP_699202 (OMIM: 609733) ligand of Numb protein X  ( 690)  421 68.0 4.2e-10
XP_016875923 (OMIM: 609733) PREDICTED: ligand of N ( 690)  421 68.0 4.2e-10
XP_016872774 (OMIM: 603583) PREDICTED: disks large ( 796)  364 60.8 6.7e-08
XP_016872770 (OMIM: 603583) PREDICTED: disks large ( 820)  364 60.9 6.9e-08
XP_016872769 (OMIM: 603583) PREDICTED: disks large ( 820)  364 60.9 6.9e-08
XP_016872768 (OMIM: 603583) PREDICTED: disks large ( 821)  364 60.9 6.9e-08
XP_016872765 (OMIM: 603583) PREDICTED: disks large ( 848)  364 60.9   7e-08
NP_001287912 (OMIM: 603583) disks large homolog 2  ( 852)  364 60.9   7e-08
XP_016872763 (OMIM: 603583) PREDICTED: disks large ( 866)  364 60.9 7.1e-08
NP_001355 (OMIM: 603583) disks large homolog 2 iso ( 870)  364 60.9 7.1e-08
XP_016872761 (OMIM: 603583) PREDICTED: disks large ( 871)  364 60.9 7.1e-08
XP_016872760 (OMIM: 603583) PREDICTED: disks large ( 872)  364 60.9 7.2e-08
XP_016872759 (OMIM: 603583) PREDICTED: disks large ( 873)  364 60.9 7.2e-08


>>XP_006716951 (OMIM: 603785,615219) PREDICTED: multiple  (2041 aa)
 initn: 13162 init1: 13162 opt: 13162  Z-score: 8969.1  bits: 1673.2 E(85289):    0
Smith-Waterman score: 13162; 100.0% identity (100.0% similar) in 2041 aa overlap (1-2041:1-2041)

               10        20        30        40        50        60
pF1KB0 MLEAIDKNRALHAAERLQTKLRERGDVANEDKLSLLKSVLQSPLFSQILSLQTSVQQLKD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 MLEAIDKNRALHAAERLQTKLRERGDVANEDKLSLLKSVLQSPLFSQILSLQTSVQQLKD
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB0 QVNIATSATSNIEYAHVPHLSPAVIPTLQNESFLLSPNNGNLEALTGPGIPHINGKPACD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 QVNIATSATSNIEYAHVPHLSPAVIPTLQNESFLLSPNNGNLEALTGPGIPHINGKPACD
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB0 EFDQLIKNMAQGRHVEVFELLKPPSGGLGFSVVGLRSENRGELGIFVQEIQEGSVAHRDG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 EFDQLIKNMAQGRHVEVFELLKPPSGGLGFSVVGLRSENRGELGIFVQEIQEGSVAHRDG
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB0 RLKETDQILAINGQALDQTITHQQAISILQKAKDTVQLVIARGSLPQLVSPIVSRSPSAA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 RLKETDQILAINGQALDQTITHQQAISILQKAKDTVQLVIARGSLPQLVSPIVSRSPSAA
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB0 STISAHSNPVHWQHMETIELVNDGSGLGFGIIGGKATGVIVKTILPGGVADQHGRLCSGD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 STISAHSNPVHWQHMETIELVNDGSGLGFGIIGGKATGVIVKTILPGGVADQHGRLCSGD
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB0 HILKIGDTDLAGMSSEQVAQVLRQCGNRVKLMIARGAIEERTAPTALGITLSSSPTSTPE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 HILKIGDTDLAGMSSEQVAQVLRQCGNRVKLMIARGAIEERTAPTALGITLSSSPTSTPE
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB0 LRVDASTQKGEESETFDVELTKNVQGLGITIAGYIGDKKLEPSGIFVKSITKSSAVEHDG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LRVDASTQKGEESETFDVELTKNVQGLGITIAGYIGDKKLEPSGIFVKSITKSSAVEHDG
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KB0 RIQIGDQIIAVDGTNLQGFTNQQAVEVLRHTGQTVLLTLMRRGMKQEAELMSREDVTKDA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 RIQIGDQIIAVDGTNLQGFTNQQAVEVLRHTGQTVLLTLMRRGMKQEAELMSREDVTKDA
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KB0 DLSPVNASIIKENYEKDEDFLSSTRNTNILPTEEEGYPLLSAEIEEIEDAQKQEAALLTK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 DLSPVNASIIKENYEKDEDFLSSTRNTNILPTEEEGYPLLSAEIEEIEDAQKQEAALLTK
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KB0 WQRIMGINYEIVVAHVSKFSENSGLGISLEATVGHHFIRSVLPEGPVGHSGKLFSGDELL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 WQRIMGINYEIVVAHVSKFSENSGLGISLEATVGHHFIRSVLPEGPVGHSGKLFSGDELL
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KB0 EVNGITLLGENHQDVVNILKELPIEVTMVCCRRTVPPTTQSELDSLDLCDIELTEKPHVD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 EVNGITLLGENHQDVVNILKELPIEVTMVCCRRTVPPTTQSELDSLDLCDIELTEKPHVD
              610       620       630       640       650       660

              670       680       690       700       710       720
pF1KB0 LGEFIGSSETEDPVLAMTDAGQSTEEVQAPLAMWEAGIQHIELEKGSKGLGFSILDYQDP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LGEFIGSSETEDPVLAMTDAGQSTEEVQAPLAMWEAGIQHIELEKGSKGLGFSILDYQDP
              670       680       690       700       710       720

              730       740       750       760       770       780
pF1KB0 IDPASTVIIIRSLVPGGIAEKDGRLLPGDRLMFVNDVNLENSSLEEAVEALKGAPSGTVR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 IDPASTVIIIRSLVPGGIAEKDGRLLPGDRLMFVNDVNLENSSLEEAVEALKGAPSGTVR
              730       740       750       760       770       780

              790       800       810       820       830       840
pF1KB0 IGVAKPLPLSPEEGYVSAKEDSFLYPPHSCEEAGLADKPLFRADLALVGTNDADLVDEST
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 IGVAKPLPLSPEEGYVSAKEDSFLYPPHSCEEAGLADKPLFRADLALVGTNDADLVDEST
              790       800       810       820       830       840

              850       860       870       880       890       900
pF1KB0 FESPYSPENDSIYSTQASILSLHGSSCGDGLNYGSSLPSSPPKDVIENSCDPVLDLHMSL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 FESPYSPENDSIYSTQASILSLHGSSCGDGLNYGSSLPSSPPKDVIENSCDPVLDLHMSL
              850       860       870       880       890       900

              910       920       930       940       950       960
pF1KB0 EELYTQNLLQRQDENTPSVDISMGPASGFTINDYTPANAIEQQYECENTIVWTESHLPSE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 EELYTQNLLQRQDENTPSVDISMGPASGFTINDYTPANAIEQQYECENTIVWTESHLPSE
              910       920       930       940       950       960

              970       980       990      1000      1010      1020
pF1KB0 VISSAELPSVLPDSAGKGSEYLLEQSSLACNAECVMLQNVSKESFERTINIAKGNSSLGM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 VISSAELPSVLPDSAGKGSEYLLEQSSLACNAECVMLQNVSKESFERTINIAKGNSSLGM
              970       980       990      1000      1010      1020

             1030      1040      1050      1060      1070      1080
pF1KB0 TVSANKDGLGMIVRSIIHGGAISRDGRIAIGDCILSINEESTISVTNAQARAMLRRHSLI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 TVSANKDGLGMIVRSIIHGGAISRDGRIAIGDCILSINEESTISVTNAQARAMLRRHSLI
             1030      1040      1050      1060      1070      1080

             1090      1100      1110      1120      1130      1140
pF1KB0 GPDIKITYVPAEHLEEFKISLGQQSGRVMALDIFSSYTGRDIPELPEREEGEGEESELQN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 GPDIKITYVPAEHLEEFKISLGQQSGRVMALDIFSSYTGRDIPELPEREEGEGEESELQN
             1090      1100      1110      1120      1130      1140

             1150      1160      1170      1180      1190      1200
pF1KB0 TAYSNWNQPRRVELWREPSKSLGISIVGGRGMGSRLSNGEVMRGIFIKHVLEDSPAGKNG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 TAYSNWNQPRRVELWREPSKSLGISIVGGRGMGSRLSNGEVMRGIFIKHVLEDSPAGKNG
             1150      1160      1170      1180      1190      1200

             1210      1220      1230      1240      1250      1260
pF1KB0 TLKPGDRIVEVDGMDLRDASHEQAVEAIRKAGNPVVFMVQSIINRPRKSPLPSLLHNLYP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 TLKPGDRIVEVDGMDLRDASHEQAVEAIRKAGNPVVFMVQSIINRPRKSPLPSLLHNLYP
             1210      1220      1230      1240      1250      1260

             1270      1280      1290      1300      1310      1320
pF1KB0 KYNFSSTNPFADSLQINADKAPSQSESEPEKAPLCSVPPPPPSAFAEMGSDHTQSSASKI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 KYNFSSTNPFADSLQINADKAPSQSESEPEKAPLCSVPPPPPSAFAEMGSDHTQSSASKI
             1270      1280      1290      1300      1310      1320

             1330      1340      1350      1360      1370      1380
pF1KB0 SQDVDKEDEFGYSWKNIRERYGTLTGELHMIELEKGHSGLGLSLAGNKDRSRMSVFIVGI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 SQDVDKEDEFGYSWKNIRERYGTLTGELHMIELEKGHSGLGLSLAGNKDRSRMSVFIVGI
             1330      1340      1350      1360      1370      1380

             1390      1400      1410      1420      1430      1440
pF1KB0 DPNGAAGKDGRLQIADELLEINGQILYGRSHQNASSIIKCAPSKVKIIFIRNKDAVNQMA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 DPNGAAGKDGRLQIADELLEINGQILYGRSHQNASSIIKCAPSKVKIIFIRNKDAVNQMA
             1390      1400      1410      1420      1430      1440

             1450      1460      1470      1480      1490      1500
pF1KB0 VCPGNAVEPLPSNSENLQNKETEPTVTTSDAAVDLSSFKNVQHLELPKDQGGLGIAISEE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 VCPGNAVEPLPSNSENLQNKETEPTVTTSDAAVDLSSFKNVQHLELPKDQGGLGIAISEE
             1450      1460      1470      1480      1490      1500

             1510      1520      1530      1540      1550      1560
pF1KB0 DTLSGVIIKSLTEHGVAATDGRLKVGDQILAVDDEIVVGYPIEKFISLLKTAKMTVKLTI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 DTLSGVIIKSLTEHGVAATDGRLKVGDQILAVDDEIVVGYPIEKFISLLKTAKMTVKLTI
             1510      1520      1530      1540      1550      1560

             1570      1580      1590      1600      1610      1620
pF1KB0 HAENPDSQAVPSAAGAASGEKKNSSQSLMVPQSGSPEPESIRNTSRSSTPAIFASDPATC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 HAENPDSQAVPSAAGAASGEKKNSSQSLMVPQSGSPEPESIRNTSRSSTPAIFASDPATC
             1570      1580      1590      1600      1610      1620

             1630      1640      1650      1660      1670      1680
pF1KB0 PIIPGCETTIEISKGRTGLGLSIVGGSDTLLGAIIIHEVYEEGAACKDGRLWAGDQILEV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 PIIPGCETTIEISKGRTGLGLSIVGGSDTLLGAIIIHEVYEEGAACKDGRLWAGDQILEV
             1630      1640      1650      1660      1670      1680

             1690      1700      1710      1720      1730      1740
pF1KB0 NGIDLRKATHDEAINVLRQTPQRVRLTLYRDEAPYKEEEVCDTLTIELQKKPGKGLGLSI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 NGIDLRKATHDEAINVLRQTPQRVRLTLYRDEAPYKEEEVCDTLTIELQKKPGKGLGLSI
             1690      1700      1710      1720      1730      1740

             1750      1760      1770      1780      1790      1800
pF1KB0 VGKRNDTGVFVSDIVKGGIADADGRLMQGDQILMVNGEDVRNATQEAVAALLKVSEGSLS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 VGKRNDTGVFVSDIVKGGIADADGRLMQGDQILMVNGEDVRNATQEAVAALLKVSEGSLS
             1750      1760      1770      1780      1790      1800

             1810      1820      1830      1840      1850      1860
pF1KB0 SFTFPLSGSSTSESLESSSKKNALASEIQGLRTVEMKKGPTDSLGISIAGGVGSPLGDVP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 SFTFPLSGSSTSESLESSSKKNALASEIQGLRTVEMKKGPTDSLGISIAGGVGSPLGDVP
             1810      1820      1830      1840      1850      1860

             1870      1880      1890      1900      1910      1920
pF1KB0 IFIAMMHPTGVAAQTQKLRVGDRIVTICGTSTEGMTHTQAVNLLKNASGSIEMQVVAGGD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 IFIAMMHPTGVAAQTQKLRVGDRIVTICGTSTEGMTHTQAVNLLKNASGSIEMQVVAGGD
             1870      1880      1890      1900      1910      1920

             1930      1940      1950      1960      1970      1980
pF1KB0 VSVVTGHQQEPASSSLSFTGLTSSSIFQDDLGPPQCKSITLERGPDGLGFSIVGGYGSPH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 VSVVTGHQQEPASSSLSFTGLTSSSIFQDDLGPPQCKSITLERGPDGLGFSIVGGYGSPH
             1930      1940      1950      1960      1970      1980

             1990      2000      2010      2020      2030      2040
pF1KB0 GDLPIYVKTVFAKGAASEDGRLKRGDQIIAVNGQSLEGVTHEEAVAILKRTKGTVTLMVL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 GDLPIYVKTVFAKGAASEDGRLKRGDQIIAVNGQSLEGVTHEEAVAILKRTKGTVTLMVL
             1990      2000      2010      2020      2030      2040

        
pF1KB0 S
       :
XP_006 S
        

>>NP_003820 (OMIM: 603785,615219) multiple PDZ domain pr  (2041 aa)
 initn: 13162 init1: 13162 opt: 13162  Z-score: 8969.1  bits: 1673.2 E(85289):    0
Smith-Waterman score: 13162; 100.0% identity (100.0% similar) in 2041 aa overlap (1-2041:1-2041)

               10        20        30        40        50        60
pF1KB0 MLEAIDKNRALHAAERLQTKLRERGDVANEDKLSLLKSVLQSPLFSQILSLQTSVQQLKD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 MLEAIDKNRALHAAERLQTKLRERGDVANEDKLSLLKSVLQSPLFSQILSLQTSVQQLKD
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB0 QVNIATSATSNIEYAHVPHLSPAVIPTLQNESFLLSPNNGNLEALTGPGIPHINGKPACD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 QVNIATSATSNIEYAHVPHLSPAVIPTLQNESFLLSPNNGNLEALTGPGIPHINGKPACD
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB0 EFDQLIKNMAQGRHVEVFELLKPPSGGLGFSVVGLRSENRGELGIFVQEIQEGSVAHRDG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 EFDQLIKNMAQGRHVEVFELLKPPSGGLGFSVVGLRSENRGELGIFVQEIQEGSVAHRDG
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB0 RLKETDQILAINGQALDQTITHQQAISILQKAKDTVQLVIARGSLPQLVSPIVSRSPSAA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 RLKETDQILAINGQALDQTITHQQAISILQKAKDTVQLVIARGSLPQLVSPIVSRSPSAA
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB0 STISAHSNPVHWQHMETIELVNDGSGLGFGIIGGKATGVIVKTILPGGVADQHGRLCSGD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 STISAHSNPVHWQHMETIELVNDGSGLGFGIIGGKATGVIVKTILPGGVADQHGRLCSGD
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB0 HILKIGDTDLAGMSSEQVAQVLRQCGNRVKLMIARGAIEERTAPTALGITLSSSPTSTPE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 HILKIGDTDLAGMSSEQVAQVLRQCGNRVKLMIARGAIEERTAPTALGITLSSSPTSTPE
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB0 LRVDASTQKGEESETFDVELTKNVQGLGITIAGYIGDKKLEPSGIFVKSITKSSAVEHDG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 LRVDASTQKGEESETFDVELTKNVQGLGITIAGYIGDKKLEPSGIFVKSITKSSAVEHDG
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KB0 RIQIGDQIIAVDGTNLQGFTNQQAVEVLRHTGQTVLLTLMRRGMKQEAELMSREDVTKDA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 RIQIGDQIIAVDGTNLQGFTNQQAVEVLRHTGQTVLLTLMRRGMKQEAELMSREDVTKDA
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KB0 DLSPVNASIIKENYEKDEDFLSSTRNTNILPTEEEGYPLLSAEIEEIEDAQKQEAALLTK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 DLSPVNASIIKENYEKDEDFLSSTRNTNILPTEEEGYPLLSAEIEEIEDAQKQEAALLTK
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KB0 WQRIMGINYEIVVAHVSKFSENSGLGISLEATVGHHFIRSVLPEGPVGHSGKLFSGDELL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 WQRIMGINYEIVVAHVSKFSENSGLGISLEATVGHHFIRSVLPEGPVGHSGKLFSGDELL
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KB0 EVNGITLLGENHQDVVNILKELPIEVTMVCCRRTVPPTTQSELDSLDLCDIELTEKPHVD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 EVNGITLLGENHQDVVNILKELPIEVTMVCCRRTVPPTTQSELDSLDLCDIELTEKPHVD
              610       620       630       640       650       660

              670       680       690       700       710       720
pF1KB0 LGEFIGSSETEDPVLAMTDAGQSTEEVQAPLAMWEAGIQHIELEKGSKGLGFSILDYQDP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 LGEFIGSSETEDPVLAMTDAGQSTEEVQAPLAMWEAGIQHIELEKGSKGLGFSILDYQDP
              670       680       690       700       710       720

              730       740       750       760       770       780
pF1KB0 IDPASTVIIIRSLVPGGIAEKDGRLLPGDRLMFVNDVNLENSSLEEAVEALKGAPSGTVR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 IDPASTVIIIRSLVPGGIAEKDGRLLPGDRLMFVNDVNLENSSLEEAVEALKGAPSGTVR
              730       740       750       760       770       780

              790       800       810       820       830       840
pF1KB0 IGVAKPLPLSPEEGYVSAKEDSFLYPPHSCEEAGLADKPLFRADLALVGTNDADLVDEST
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 IGVAKPLPLSPEEGYVSAKEDSFLYPPHSCEEAGLADKPLFRADLALVGTNDADLVDEST
              790       800       810       820       830       840

              850       860       870       880       890       900
pF1KB0 FESPYSPENDSIYSTQASILSLHGSSCGDGLNYGSSLPSSPPKDVIENSCDPVLDLHMSL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 FESPYSPENDSIYSTQASILSLHGSSCGDGLNYGSSLPSSPPKDVIENSCDPVLDLHMSL
              850       860       870       880       890       900

              910       920       930       940       950       960
pF1KB0 EELYTQNLLQRQDENTPSVDISMGPASGFTINDYTPANAIEQQYECENTIVWTESHLPSE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 EELYTQNLLQRQDENTPSVDISMGPASGFTINDYTPANAIEQQYECENTIVWTESHLPSE
              910       920       930       940       950       960

              970       980       990      1000      1010      1020
pF1KB0 VISSAELPSVLPDSAGKGSEYLLEQSSLACNAECVMLQNVSKESFERTINIAKGNSSLGM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 VISSAELPSVLPDSAGKGSEYLLEQSSLACNAECVMLQNVSKESFERTINIAKGNSSLGM
              970       980       990      1000      1010      1020

             1030      1040      1050      1060      1070      1080
pF1KB0 TVSANKDGLGMIVRSIIHGGAISRDGRIAIGDCILSINEESTISVTNAQARAMLRRHSLI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 TVSANKDGLGMIVRSIIHGGAISRDGRIAIGDCILSINEESTISVTNAQARAMLRRHSLI
             1030      1040      1050      1060      1070      1080

             1090      1100      1110      1120      1130      1140
pF1KB0 GPDIKITYVPAEHLEEFKISLGQQSGRVMALDIFSSYTGRDIPELPEREEGEGEESELQN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 GPDIKITYVPAEHLEEFKISLGQQSGRVMALDIFSSYTGRDIPELPEREEGEGEESELQN
             1090      1100      1110      1120      1130      1140

             1150      1160      1170      1180      1190      1200
pF1KB0 TAYSNWNQPRRVELWREPSKSLGISIVGGRGMGSRLSNGEVMRGIFIKHVLEDSPAGKNG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 TAYSNWNQPRRVELWREPSKSLGISIVGGRGMGSRLSNGEVMRGIFIKHVLEDSPAGKNG
             1150      1160      1170      1180      1190      1200

             1210      1220      1230      1240      1250      1260
pF1KB0 TLKPGDRIVEVDGMDLRDASHEQAVEAIRKAGNPVVFMVQSIINRPRKSPLPSLLHNLYP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 TLKPGDRIVEVDGMDLRDASHEQAVEAIRKAGNPVVFMVQSIINRPRKSPLPSLLHNLYP
             1210      1220      1230      1240      1250      1260

             1270      1280      1290      1300      1310      1320
pF1KB0 KYNFSSTNPFADSLQINADKAPSQSESEPEKAPLCSVPPPPPSAFAEMGSDHTQSSASKI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 KYNFSSTNPFADSLQINADKAPSQSESEPEKAPLCSVPPPPPSAFAEMGSDHTQSSASKI
             1270      1280      1290      1300      1310      1320

             1330      1340      1350      1360      1370      1380
pF1KB0 SQDVDKEDEFGYSWKNIRERYGTLTGELHMIELEKGHSGLGLSLAGNKDRSRMSVFIVGI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 SQDVDKEDEFGYSWKNIRERYGTLTGELHMIELEKGHSGLGLSLAGNKDRSRMSVFIVGI
             1330      1340      1350      1360      1370      1380

             1390      1400      1410      1420      1430      1440
pF1KB0 DPNGAAGKDGRLQIADELLEINGQILYGRSHQNASSIIKCAPSKVKIIFIRNKDAVNQMA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 DPNGAAGKDGRLQIADELLEINGQILYGRSHQNASSIIKCAPSKVKIIFIRNKDAVNQMA
             1390      1400      1410      1420      1430      1440

             1450      1460      1470      1480      1490      1500
pF1KB0 VCPGNAVEPLPSNSENLQNKETEPTVTTSDAAVDLSSFKNVQHLELPKDQGGLGIAISEE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 VCPGNAVEPLPSNSENLQNKETEPTVTTSDAAVDLSSFKNVQHLELPKDQGGLGIAISEE
             1450      1460      1470      1480      1490      1500

             1510      1520      1530      1540      1550      1560
pF1KB0 DTLSGVIIKSLTEHGVAATDGRLKVGDQILAVDDEIVVGYPIEKFISLLKTAKMTVKLTI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 DTLSGVIIKSLTEHGVAATDGRLKVGDQILAVDDEIVVGYPIEKFISLLKTAKMTVKLTI
             1510      1520      1530      1540      1550      1560

             1570      1580      1590      1600      1610      1620
pF1KB0 HAENPDSQAVPSAAGAASGEKKNSSQSLMVPQSGSPEPESIRNTSRSSTPAIFASDPATC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 HAENPDSQAVPSAAGAASGEKKNSSQSLMVPQSGSPEPESIRNTSRSSTPAIFASDPATC
             1570      1580      1590      1600      1610      1620

             1630      1640      1650      1660      1670      1680
pF1KB0 PIIPGCETTIEISKGRTGLGLSIVGGSDTLLGAIIIHEVYEEGAACKDGRLWAGDQILEV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 PIIPGCETTIEISKGRTGLGLSIVGGSDTLLGAIIIHEVYEEGAACKDGRLWAGDQILEV
             1630      1640      1650      1660      1670      1680

             1690      1700      1710      1720      1730      1740
pF1KB0 NGIDLRKATHDEAINVLRQTPQRVRLTLYRDEAPYKEEEVCDTLTIELQKKPGKGLGLSI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 NGIDLRKATHDEAINVLRQTPQRVRLTLYRDEAPYKEEEVCDTLTIELQKKPGKGLGLSI
             1690      1700      1710      1720      1730      1740

             1750      1760      1770      1780      1790      1800
pF1KB0 VGKRNDTGVFVSDIVKGGIADADGRLMQGDQILMVNGEDVRNATQEAVAALLKVSEGSLS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 VGKRNDTGVFVSDIVKGGIADADGRLMQGDQILMVNGEDVRNATQEAVAALLKVSEGSLS
             1750      1760      1770      1780      1790      1800

             1810      1820      1830      1840      1850      1860
pF1KB0 SFTFPLSGSSTSESLESSSKKNALASEIQGLRTVEMKKGPTDSLGISIAGGVGSPLGDVP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 SFTFPLSGSSTSESLESSSKKNALASEIQGLRTVEMKKGPTDSLGISIAGGVGSPLGDVP
             1810      1820      1830      1840      1850      1860

             1870      1880      1890      1900      1910      1920
pF1KB0 IFIAMMHPTGVAAQTQKLRVGDRIVTICGTSTEGMTHTQAVNLLKNASGSIEMQVVAGGD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 IFIAMMHPTGVAAQTQKLRVGDRIVTICGTSTEGMTHTQAVNLLKNASGSIEMQVVAGGD
             1870      1880      1890      1900      1910      1920

             1930      1940      1950      1960      1970      1980
pF1KB0 VSVVTGHQQEPASSSLSFTGLTSSSIFQDDLGPPQCKSITLERGPDGLGFSIVGGYGSPH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 VSVVTGHQQEPASSSLSFTGLTSSSIFQDDLGPPQCKSITLERGPDGLGFSIVGGYGSPH
             1930      1940      1950      1960      1970      1980

             1990      2000      2010      2020      2030      2040
pF1KB0 GDLPIYVKTVFAKGAASEDGRLKRGDQIIAVNGQSLEGVTHEEAVAILKRTKGTVTLMVL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 GDLPIYVKTVFAKGAASEDGRLKRGDQIIAVNGQSLEGVTHEEAVAILKRTKGTVTLMVL
             1990      2000      2010      2020      2030      2040

        
pF1KB0 S
       :
NP_003 S
        

>>XP_016870741 (OMIM: 603785,615219) PREDICTED: multiple  (2042 aa)
 initn: 12229 init1: 10671 opt: 12155  Z-score: 8283.7  bits: 1546.3 E(85289):    0
Smith-Waterman score: 12835; 97.2% identity (97.2% similar) in 2070 aa overlap (1-2041:1-2042)

               10        20        30        40        50        60
pF1KB0 MLEAIDKNRALHAAERLQTKLRERGDVANEDKLSLLKSVLQSPLFSQILSLQTSVQQLKD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MLEAIDKNRALHAAERLQTKLRERGDVANEDKLSLLKSVLQSPLFSQILSLQTSVQQLKD
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB0 QVNIATSATSNIEYAHVPHLSPAVIPTLQNESFLLSPNNGNLEALTGPGIPHINGKPACD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QVNIATSATSNIEYAHVPHLSPAVIPTLQNESFLLSPNNGNLEALTGPGIPHINGKPACD
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB0 EFDQLIKNMAQGRHVEVFELLKPPSGGLGFSVVGLRSENRGELGIFVQEIQEGSVAHRDG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EFDQLIKNMAQGRHVEVFELLKPPSGGLGFSVVGLRSENRGELGIFVQEIQEGSVAHRDG
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB0 RLKETDQILAINGQALDQTITHQQAISILQKAKDTVQLVIARGSLPQLVSPIVSRSPSAA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RLKETDQILAINGQALDQTITHQQAISILQKAKDTVQLVIARGSLPQLVSPIVSRSPSAA
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB0 STISAHSNPVHWQHMETIELVNDGSGLGFGIIGGKATGVIVKTILPGGVADQHGRLCSGD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 STISAHSNPVHWQHMETIELVNDGSGLGFGIIGGKATGVIVKTILPGGVADQHGRLCSGD
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB0 HILKIGDTDLAGMSSEQVAQVLRQCGNRVKLMIARGAIEERTAPTALGITLSSSPTSTPE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HILKIGDTDLAGMSSEQVAQVLRQCGNRVKLMIARGAIEERTAPTALGITLSSSPTSTPE
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB0 LRVDASTQKGEESETFDVELTKNVQGLGITIAGYIGDKKLEPSGIFVKSITKSSAVEHDG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LRVDASTQKGEESETFDVELTKNVQGLGITIAGYIGDKKLEPSGIFVKSITKSSAVEHDG
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KB0 RIQIGDQIIAVDGTNLQGFTNQQAVEVLRHTGQTVLLTLMRRGMKQEAELMSREDVTKDA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RIQIGDQIIAVDGTNLQGFTNQQAVEVLRHTGQTVLLTLMRRGMKQEAELMSREDVTKDA
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KB0 DLSPVNASIIKENYEKDEDFLSSTRNTNILPTEEEGYPLLSAEIEEIEDAQKQEAALLTK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DLSPVNASIIKENYEKDEDFLSSTRNTNILPTEEEGYPLLSAEIEEIEDAQKQEAALLTK
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KB0 WQRIMGINYEIVVAHVSKFSENSGLGISLEATVGHHFIRSVLPEGPVGHSGKLFSGDELL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 WQRIMGINYEIVVAHVSKFSENSGLGISLEATVGHHFIRSVLPEGPVGHSGKLFSGDELL
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KB0 EVNGITLLGENHQDVVNILKELPIEVTMVCCRRTVPPTTQSELDSLDLCDIELTEKPHVD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EVNGITLLGENHQDVVNILKELPIEVTMVCCRRTVPPTTQSELDSLDLCDIELTEKPHVD
              610       620       630       640       650       660

              670       680       690       700       710       720
pF1KB0 LGEFIGSSETEDPVLAMTDAGQSTEEVQAPLAMWEAGIQHIELEKGSKGLGFSILDYQDP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LGEFIGSSETEDPVLAMTDAGQSTEEVQAPLAMWEAGIQHIELEKGSKGLGFSILDYQDP
              670       680       690       700       710       720

              730       740       750       760       770       780
pF1KB0 IDPASTVIIIRSLVPGGIAEKDGRLLPGDRLMFVNDVNLENSSLEEAVEALKGAPSGTVR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IDPASTVIIIRSLVPGGIAEKDGRLLPGDRLMFVNDVNLENSSLEEAVEALKGAPSGTVR
              730       740       750       760       770       780

              790       800       810       820       830       840
pF1KB0 IGVAKPLPLSPEEGYVSAKEDSFLYPPHSCEEAGLADKPLFRADLALVGTNDADLVDEST
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IGVAKPLPLSPEEGYVSAKEDSFLYPPHSCEEAGLADKPLFRADLALVGTNDADLVDEST
              790       800       810       820       830       840

              850       860       870       880       890       900
pF1KB0 FESPYSPENDSIYSTQASILSLHGSSCGDGLNYGSSLPSSPPKDVIENSCDPVLDLHMSL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FESPYSPENDSIYSTQASILSLHGSSCGDGLNYGSSLPSSPPKDVIENSCDPVLDLHMSL
              850       860       870       880       890       900

              910       920       930       940       950       960
pF1KB0 EELYTQNLLQRQDENTPSVDISMGPASGFTINDYTPANAIEQQYECENTIVWTESHLPSE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EELYTQNLLQRQDENTPSVDISMGPASGFTINDYTPANAIEQQYECENTIVWTESHLPSE
              910       920       930       940       950       960

              970       980       990      1000      1010      1020
pF1KB0 VISSAELPSVLPDSAGKGSEYLLEQSSLACNAECVMLQNVSKESFERTINIAKGNSSLGM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VISSAELPSVLPDSAGKGSEYLLEQSSLACNAECVMLQNVSKESFERTINIAKGNSSLGM
              970       980       990      1000      1010      1020

             1030      1040      1050      1060      1070      1080
pF1KB0 TVSANKDGLGMIVRSIIHGGAISRDGRIAIGDCILSINEESTISVTNAQARAMLRRHSLI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TVSANKDGLGMIVRSIIHGGAISRDGRIAIGDCILSINEESTISVTNAQARAMLRRHSLI
             1030      1040      1050      1060      1070      1080

             1090      1100      1110      1120      1130      1140
pF1KB0 GPDIKITYVPAEHLEEFKISLGQQSGRVMALDIFSSYTGRDIPELPEREEGEGEESELQN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GPDIKITYVPAEHLEEFKISLGQQSGRVMALDIFSSYTGRDIPELPEREEGEGEESELQN
             1090      1100      1110      1120      1130      1140

             1150      1160      1170      1180      1190      1200
pF1KB0 TAYSNWNQPRRVELWREPSKSLGISIVGGRGMGSRLSNGEVMRGIFIKHVLEDSPAGKNG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TAYSNWNQPRRVELWREPSKSLGISIVGGRGMGSRLSNGEVMRGIFIKHVLEDSPAGKNG
             1150      1160      1170      1180      1190      1200

             1210      1220      1230      1240      1250      1260
pF1KB0 TLKPGDRIVEVDGMDLRDASHEQAVEAIRKAGNPVVFMVQSIINRPRKSPLPSLLHNLYP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TLKPGDRIVEVDGMDLRDASHEQAVEAIRKAGNPVVFMVQSIINRPRKSPLPSLLHNLYP
             1210      1220      1230      1240      1250      1260

             1270      1280      1290      1300      1310      1320
pF1KB0 KYNFSSTNPFADSLQINADKAPSQSESEPEKAPLCSVPPPPPSAFAEMGSDHTQSSASKI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KYNFSSTNPFADSLQINADKAPSQSESEPEKAPLCSVPPPPPSAFAEMGSDHTQSSASKI
             1270      1280      1290      1300      1310      1320

             1330      1340      1350      1360      1370      1380
pF1KB0 SQDVDKEDEFGYSWKNIRERYGTLTGELHMIELEKGHSGLGLSLAGNKDRSRMSVFIVGI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SQDVDKEDEFGYSWKNIRERYGTLTGELHMIELEKGHSGLGLSLAGNKDRSRMSVFIVGI
             1330      1340      1350      1360      1370      1380

             1390      1400      1410      1420      1430      1440
pF1KB0 DPNGAAGKDGRLQIADELLEINGQILYGRSHQNASSIIKCAPSKVKIIFIRNKDAVNQMA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DPNGAAGKDGRLQIADELLEINGQILYGRSHQNASSIIKCAPSKVKIIFIRNKDAVNQMA
             1390      1400      1410      1420      1430      1440

             1450      1460      1470      1480      1490      1500
pF1KB0 VCPGNAVEPLPSNSENLQNKETEPTVTTSDAAVDLSSFKNVQHLELPKDQGGLGIAISEE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VCPGNAVEPLPSNSENLQNKETEPTVTTSDAAVDLSSFKNVQHLELPKDQGGLGIAISEE
             1450      1460      1470      1480      1490      1500

             1510      1520      1530      1540      1550      1560
pF1KB0 DTLSGVIIKSLTEHGVAATDGRLKVGDQILAVDDEIVVGYPIEKFISLLKTAKMTVKLTI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DTLSGVIIKSLTEHGVAATDGRLKVGDQILAVDDEIVVGYPIEKFISLLKTAKMTVKLTI
             1510      1520      1530      1540      1550      1560

             1570      1580      1590      1600      1610      1620
pF1KB0 HAENPDSQAVPSAAGAASGEKKNSSQSLMVPQSGSPEPESIRNTSRSSTPAIFASDPATC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HAENPDSQAVPSAAGAASGEKKNSSQSLMVPQSGSPEPESIRNTSRSSTPAIFASDPATC
             1570      1580      1590      1600      1610      1620

             1630      1640      1650      1660      1670      1680
pF1KB0 PIIPGCETTIEISKGRTGLGLSIVGGSDTLLGAIIIHEVYEEGAACKDGRLWAGDQILEV
       :::::::::::::::::::::::::::::::                            :
XP_016 PIIPGCETTIEISKGRTGLGLSIVGGSDTLL----------------------------V
             1630      1640      1650                              

             1690      1700      1710      1720      1730      1740
pF1KB0 NGIDLRKATHDEAINVLRQTPQRVRLTLYRDEAPYKEEEVCDTLTIELQKKPGKGLGLSI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NGIDLRKATHDEAINVLRQTPQRVRLTLYRDEAPYKEEEVCDTLTIELQKKPGKGLGLSI
           1660      1670      1680      1690      1700      1710  

             1750      1760      1770      1780      1790          
pF1KB0 VGKRNDTGVFVSDIVKGGIADADGRLMQGDQILMVNGEDVRNATQEAVAALLK-------
       :::::::::::::::::::::::::::::::::::::::::::::::::::::       
XP_016 VGKRNDTGVFVSDIVKGGIADADGRLMQGDQILMVNGEDVRNATQEAVAALLKCSLGTVT
           1720      1730      1740      1750      1760      1770  

                                1800      1810      1820      1830 
pF1KB0 ----------------------VSEGSLSSFTFPLSGSSTSESLESSSKKNALASEIQGL
                             ::::::::::::::::::::::::::::::::::::::
XP_016 LEVGRIKAGPFHSERRPSQSSQVSEGSLSSFTFPLSGSSTSESLESSSKKNALASEIQGL
           1780      1790      1800      1810      1820      1830  

            1840      1850      1860      1870      1880      1890 
pF1KB0 RTVEMKKGPTDSLGISIAGGVGSPLGDVPIFIAMMHPTGVAAQTQKLRVGDRIVTICGTS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RTVEMKKGPTDSLGISIAGGVGSPLGDVPIFIAMMHPTGVAAQTQKLRVGDRIVTICGTS
           1840      1850      1860      1870      1880      1890  

            1900      1910      1920      1930      1940      1950 
pF1KB0 TEGMTHTQAVNLLKNASGSIEMQVVAGGDVSVVTGHQQEPASSSLSFTGLTSSSIFQDDL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TEGMTHTQAVNLLKNASGSIEMQVVAGGDVSVVTGHQQEPASSSLSFTGLTSSSIFQDDL
           1900      1910      1920      1930      1940      1950  

            1960      1970      1980      1990      2000      2010 
pF1KB0 GPPQCKSITLERGPDGLGFSIVGGYGSPHGDLPIYVKTVFAKGAASEDGRLKRGDQIIAV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GPPQCKSITLERGPDGLGFSIVGGYGSPHGDLPIYVKTVFAKGAASEDGRLKRGDQIIAV
           1960      1970      1980      1990      2000      2010  

            2020      2030      2040 
pF1KB0 NGQSLEGVTHEEAVAILKRTKGTVTLMVLS
       ::::::::::::::::::::::::::::::
XP_016 NGQSLEGVTHEEAVAILKRTKGTVTLMVLS
           2020      2030      2040  

>>XP_006716950 (OMIM: 603785,615219) PREDICTED: multiple  (2070 aa)
 initn: 11829 init1: 11606 opt: 11606  Z-score: 7909.9  bits: 1477.2 E(85289):    0
Smith-Waterman score: 13094; 98.6% identity (98.6% similar) in 2070 aa overlap (1-2041:1-2070)

               10        20        30        40        50        60
pF1KB0 MLEAIDKNRALHAAERLQTKLRERGDVANEDKLSLLKSVLQSPLFSQILSLQTSVQQLKD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 MLEAIDKNRALHAAERLQTKLRERGDVANEDKLSLLKSVLQSPLFSQILSLQTSVQQLKD
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB0 QVNIATSATSNIEYAHVPHLSPAVIPTLQNESFLLSPNNGNLEALTGPGIPHINGKPACD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 QVNIATSATSNIEYAHVPHLSPAVIPTLQNESFLLSPNNGNLEALTGPGIPHINGKPACD
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB0 EFDQLIKNMAQGRHVEVFELLKPPSGGLGFSVVGLRSENRGELGIFVQEIQEGSVAHRDG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 EFDQLIKNMAQGRHVEVFELLKPPSGGLGFSVVGLRSENRGELGIFVQEIQEGSVAHRDG
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB0 RLKETDQILAINGQALDQTITHQQAISILQKAKDTVQLVIARGSLPQLVSPIVSRSPSAA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 RLKETDQILAINGQALDQTITHQQAISILQKAKDTVQLVIARGSLPQLVSPIVSRSPSAA
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB0 STISAHSNPVHWQHMETIELVNDGSGLGFGIIGGKATGVIVKTILPGGVADQHGRLCSGD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 STISAHSNPVHWQHMETIELVNDGSGLGFGIIGGKATGVIVKTILPGGVADQHGRLCSGD
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB0 HILKIGDTDLAGMSSEQVAQVLRQCGNRVKLMIARGAIEERTAPTALGITLSSSPTSTPE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 HILKIGDTDLAGMSSEQVAQVLRQCGNRVKLMIARGAIEERTAPTALGITLSSSPTSTPE
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB0 LRVDASTQKGEESETFDVELTKNVQGLGITIAGYIGDKKLEPSGIFVKSITKSSAVEHDG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LRVDASTQKGEESETFDVELTKNVQGLGITIAGYIGDKKLEPSGIFVKSITKSSAVEHDG
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KB0 RIQIGDQIIAVDGTNLQGFTNQQAVEVLRHTGQTVLLTLMRRGMKQEAELMSREDVTKDA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 RIQIGDQIIAVDGTNLQGFTNQQAVEVLRHTGQTVLLTLMRRGMKQEAELMSREDVTKDA
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KB0 DLSPVNASIIKENYEKDEDFLSSTRNTNILPTEEEGYPLLSAEIEEIEDAQKQEAALLTK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 DLSPVNASIIKENYEKDEDFLSSTRNTNILPTEEEGYPLLSAEIEEIEDAQKQEAALLTK
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KB0 WQRIMGINYEIVVAHVSKFSENSGLGISLEATVGHHFIRSVLPEGPVGHSGKLFSGDELL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 WQRIMGINYEIVVAHVSKFSENSGLGISLEATVGHHFIRSVLPEGPVGHSGKLFSGDELL
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KB0 EVNGITLLGENHQDVVNILKELPIEVTMVCCRRTVPPTTQSELDSLDLCDIELTEKPHVD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 EVNGITLLGENHQDVVNILKELPIEVTMVCCRRTVPPTTQSELDSLDLCDIELTEKPHVD
              610       620       630       640       650       660

              670       680       690       700       710       720
pF1KB0 LGEFIGSSETEDPVLAMTDAGQSTEEVQAPLAMWEAGIQHIELEKGSKGLGFSILDYQDP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LGEFIGSSETEDPVLAMTDAGQSTEEVQAPLAMWEAGIQHIELEKGSKGLGFSILDYQDP
              670       680       690       700       710       720

              730       740       750       760       770       780
pF1KB0 IDPASTVIIIRSLVPGGIAEKDGRLLPGDRLMFVNDVNLENSSLEEAVEALKGAPSGTVR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 IDPASTVIIIRSLVPGGIAEKDGRLLPGDRLMFVNDVNLENSSLEEAVEALKGAPSGTVR
              730       740       750       760       770       780

              790       800       810       820       830       840
pF1KB0 IGVAKPLPLSPEEGYVSAKEDSFLYPPHSCEEAGLADKPLFRADLALVGTNDADLVDEST
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 IGVAKPLPLSPEEGYVSAKEDSFLYPPHSCEEAGLADKPLFRADLALVGTNDADLVDEST
              790       800       810       820       830       840

              850       860       870       880       890       900
pF1KB0 FESPYSPENDSIYSTQASILSLHGSSCGDGLNYGSSLPSSPPKDVIENSCDPVLDLHMSL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 FESPYSPENDSIYSTQASILSLHGSSCGDGLNYGSSLPSSPPKDVIENSCDPVLDLHMSL
              850       860       870       880       890       900

              910       920       930       940       950       960
pF1KB0 EELYTQNLLQRQDENTPSVDISMGPASGFTINDYTPANAIEQQYECENTIVWTESHLPSE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 EELYTQNLLQRQDENTPSVDISMGPASGFTINDYTPANAIEQQYECENTIVWTESHLPSE
              910       920       930       940       950       960

              970       980       990      1000      1010      1020
pF1KB0 VISSAELPSVLPDSAGKGSEYLLEQSSLACNAECVMLQNVSKESFERTINIAKGNSSLGM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 VISSAELPSVLPDSAGKGSEYLLEQSSLACNAECVMLQNVSKESFERTINIAKGNSSLGM
              970       980       990      1000      1010      1020

             1030      1040      1050      1060      1070      1080
pF1KB0 TVSANKDGLGMIVRSIIHGGAISRDGRIAIGDCILSINEESTISVTNAQARAMLRRHSLI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 TVSANKDGLGMIVRSIIHGGAISRDGRIAIGDCILSINEESTISVTNAQARAMLRRHSLI
             1030      1040      1050      1060      1070      1080

             1090      1100      1110      1120      1130      1140
pF1KB0 GPDIKITYVPAEHLEEFKISLGQQSGRVMALDIFSSYTGRDIPELPEREEGEGEESELQN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 GPDIKITYVPAEHLEEFKISLGQQSGRVMALDIFSSYTGRDIPELPEREEGEGEESELQN
             1090      1100      1110      1120      1130      1140

             1150      1160      1170      1180      1190      1200
pF1KB0 TAYSNWNQPRRVELWREPSKSLGISIVGGRGMGSRLSNGEVMRGIFIKHVLEDSPAGKNG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 TAYSNWNQPRRVELWREPSKSLGISIVGGRGMGSRLSNGEVMRGIFIKHVLEDSPAGKNG
             1150      1160      1170      1180      1190      1200

             1210      1220      1230      1240      1250      1260
pF1KB0 TLKPGDRIVEVDGMDLRDASHEQAVEAIRKAGNPVVFMVQSIINRPRKSPLPSLLHNLYP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 TLKPGDRIVEVDGMDLRDASHEQAVEAIRKAGNPVVFMVQSIINRPRKSPLPSLLHNLYP
             1210      1220      1230      1240      1250      1260

             1270      1280      1290      1300      1310      1320
pF1KB0 KYNFSSTNPFADSLQINADKAPSQSESEPEKAPLCSVPPPPPSAFAEMGSDHTQSSASKI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 KYNFSSTNPFADSLQINADKAPSQSESEPEKAPLCSVPPPPPSAFAEMGSDHTQSSASKI
             1270      1280      1290      1300      1310      1320

             1330      1340      1350      1360      1370      1380
pF1KB0 SQDVDKEDEFGYSWKNIRERYGTLTGELHMIELEKGHSGLGLSLAGNKDRSRMSVFIVGI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 SQDVDKEDEFGYSWKNIRERYGTLTGELHMIELEKGHSGLGLSLAGNKDRSRMSVFIVGI
             1330      1340      1350      1360      1370      1380

             1390      1400      1410      1420      1430      1440
pF1KB0 DPNGAAGKDGRLQIADELLEINGQILYGRSHQNASSIIKCAPSKVKIIFIRNKDAVNQMA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 DPNGAAGKDGRLQIADELLEINGQILYGRSHQNASSIIKCAPSKVKIIFIRNKDAVNQMA
             1390      1400      1410      1420      1430      1440

             1450      1460      1470      1480      1490      1500
pF1KB0 VCPGNAVEPLPSNSENLQNKETEPTVTTSDAAVDLSSFKNVQHLELPKDQGGLGIAISEE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 VCPGNAVEPLPSNSENLQNKETEPTVTTSDAAVDLSSFKNVQHLELPKDQGGLGIAISEE
             1450      1460      1470      1480      1490      1500

             1510      1520      1530      1540      1550      1560
pF1KB0 DTLSGVIIKSLTEHGVAATDGRLKVGDQILAVDDEIVVGYPIEKFISLLKTAKMTVKLTI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 DTLSGVIIKSLTEHGVAATDGRLKVGDQILAVDDEIVVGYPIEKFISLLKTAKMTVKLTI
             1510      1520      1530      1540      1550      1560

             1570      1580      1590      1600      1610      1620
pF1KB0 HAENPDSQAVPSAAGAASGEKKNSSQSLMVPQSGSPEPESIRNTSRSSTPAIFASDPATC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 HAENPDSQAVPSAAGAASGEKKNSSQSLMVPQSGSPEPESIRNTSRSSTPAIFASDPATC
             1570      1580      1590      1600      1610      1620

             1630      1640      1650      1660      1670      1680
pF1KB0 PIIPGCETTIEISKGRTGLGLSIVGGSDTLLGAIIIHEVYEEGAACKDGRLWAGDQILEV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 PIIPGCETTIEISKGRTGLGLSIVGGSDTLLGAIIIHEVYEEGAACKDGRLWAGDQILEV
             1630      1640      1650      1660      1670      1680

             1690      1700      1710      1720      1730      1740
pF1KB0 NGIDLRKATHDEAINVLRQTPQRVRLTLYRDEAPYKEEEVCDTLTIELQKKPGKGLGLSI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 NGIDLRKATHDEAINVLRQTPQRVRLTLYRDEAPYKEEEVCDTLTIELQKKPGKGLGLSI
             1690      1700      1710      1720      1730      1740

             1750      1760      1770      1780      1790          
pF1KB0 VGKRNDTGVFVSDIVKGGIADADGRLMQGDQILMVNGEDVRNATQEAVAALLK-------
       :::::::::::::::::::::::::::::::::::::::::::::::::::::       
XP_006 VGKRNDTGVFVSDIVKGGIADADGRLMQGDQILMVNGEDVRNATQEAVAALLKCSLGTVT
             1750      1760      1770      1780      1790      1800

                                1800      1810      1820      1830 
pF1KB0 ----------------------VSEGSLSSFTFPLSGSSTSESLESSSKKNALASEIQGL
                             ::::::::::::::::::::::::::::::::::::::
XP_006 LEVGRIKAGPFHSERRPSQSSQVSEGSLSSFTFPLSGSSTSESLESSSKKNALASEIQGL
             1810      1820      1830      1840      1850      1860

            1840      1850      1860      1870      1880      1890 
pF1KB0 RTVEMKKGPTDSLGISIAGGVGSPLGDVPIFIAMMHPTGVAAQTQKLRVGDRIVTICGTS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 RTVEMKKGPTDSLGISIAGGVGSPLGDVPIFIAMMHPTGVAAQTQKLRVGDRIVTICGTS
             1870      1880      1890      1900      1910      1920

            1900      1910      1920      1930      1940      1950 
pF1KB0 TEGMTHTQAVNLLKNASGSIEMQVVAGGDVSVVTGHQQEPASSSLSFTGLTSSSIFQDDL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 TEGMTHTQAVNLLKNASGSIEMQVVAGGDVSVVTGHQQEPASSSLSFTGLTSSSIFQDDL
             1930      1940      1950      1960      1970      1980

            1960      1970      1980      1990      2000      2010 
pF1KB0 GPPQCKSITLERGPDGLGFSIVGGYGSPHGDLPIYVKTVFAKGAASEDGRLKRGDQIIAV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 GPPQCKSITLERGPDGLGFSIVGGYGSPHGDLPIYVKTVFAKGAASEDGRLKRGDQIIAV
             1990      2000      2010      2020      2030      2040

            2020      2030      2040 
pF1KB0 NGQSLEGVTHEEAVAILKRTKGTVTLMVLS
       ::::::::::::::::::::::::::::::
XP_006 NGQSLEGVTHEEAVAILKRTKGTVTLMVLS
             2050      2060      2070

>>XP_006716948 (OMIM: 603785,615219) PREDICTED: multiple  (2070 aa)
 initn: 11829 init1: 11606 opt: 11606  Z-score: 7909.9  bits: 1477.2 E(85289):    0
Smith-Waterman score: 13094; 98.6% identity (98.6% similar) in 2070 aa overlap (1-2041:1-2070)

               10        20        30        40        50        60
pF1KB0 MLEAIDKNRALHAAERLQTKLRERGDVANEDKLSLLKSVLQSPLFSQILSLQTSVQQLKD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 MLEAIDKNRALHAAERLQTKLRERGDVANEDKLSLLKSVLQSPLFSQILSLQTSVQQLKD
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB0 QVNIATSATSNIEYAHVPHLSPAVIPTLQNESFLLSPNNGNLEALTGPGIPHINGKPACD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 QVNIATSATSNIEYAHVPHLSPAVIPTLQNESFLLSPNNGNLEALTGPGIPHINGKPACD
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB0 EFDQLIKNMAQGRHVEVFELLKPPSGGLGFSVVGLRSENRGELGIFVQEIQEGSVAHRDG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 EFDQLIKNMAQGRHVEVFELLKPPSGGLGFSVVGLRSENRGELGIFVQEIQEGSVAHRDG
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB0 RLKETDQILAINGQALDQTITHQQAISILQKAKDTVQLVIARGSLPQLVSPIVSRSPSAA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 RLKETDQILAINGQALDQTITHQQAISILQKAKDTVQLVIARGSLPQLVSPIVSRSPSAA
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB0 STISAHSNPVHWQHMETIELVNDGSGLGFGIIGGKATGVIVKTILPGGVADQHGRLCSGD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 STISAHSNPVHWQHMETIELVNDGSGLGFGIIGGKATGVIVKTILPGGVADQHGRLCSGD
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB0 HILKIGDTDLAGMSSEQVAQVLRQCGNRVKLMIARGAIEERTAPTALGITLSSSPTSTPE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 HILKIGDTDLAGMSSEQVAQVLRQCGNRVKLMIARGAIEERTAPTALGITLSSSPTSTPE
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB0 LRVDASTQKGEESETFDVELTKNVQGLGITIAGYIGDKKLEPSGIFVKSITKSSAVEHDG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LRVDASTQKGEESETFDVELTKNVQGLGITIAGYIGDKKLEPSGIFVKSITKSSAVEHDG
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KB0 RIQIGDQIIAVDGTNLQGFTNQQAVEVLRHTGQTVLLTLMRRGMKQEAELMSREDVTKDA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 RIQIGDQIIAVDGTNLQGFTNQQAVEVLRHTGQTVLLTLMRRGMKQEAELMSREDVTKDA
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KB0 DLSPVNASIIKENYEKDEDFLSSTRNTNILPTEEEGYPLLSAEIEEIEDAQKQEAALLTK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 DLSPVNASIIKENYEKDEDFLSSTRNTNILPTEEEGYPLLSAEIEEIEDAQKQEAALLTK
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KB0 WQRIMGINYEIVVAHVSKFSENSGLGISLEATVGHHFIRSVLPEGPVGHSGKLFSGDELL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 WQRIMGINYEIVVAHVSKFSENSGLGISLEATVGHHFIRSVLPEGPVGHSGKLFSGDELL
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KB0 EVNGITLLGENHQDVVNILKELPIEVTMVCCRRTVPPTTQSELDSLDLCDIELTEKPHVD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 EVNGITLLGENHQDVVNILKELPIEVTMVCCRRTVPPTTQSELDSLDLCDIELTEKPHVD
              610       620       630       640       650       660

              670       680       690       700       710       720
pF1KB0 LGEFIGSSETEDPVLAMTDAGQSTEEVQAPLAMWEAGIQHIELEKGSKGLGFSILDYQDP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LGEFIGSSETEDPVLAMTDAGQSTEEVQAPLAMWEAGIQHIELEKGSKGLGFSILDYQDP
              670       680       690       700       710       720

              730       740       750       760       770       780
pF1KB0 IDPASTVIIIRSLVPGGIAEKDGRLLPGDRLMFVNDVNLENSSLEEAVEALKGAPSGTVR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 IDPASTVIIIRSLVPGGIAEKDGRLLPGDRLMFVNDVNLENSSLEEAVEALKGAPSGTVR
              730       740       750       760       770       780

              790       800       810       820       830       840
pF1KB0 IGVAKPLPLSPEEGYVSAKEDSFLYPPHSCEEAGLADKPLFRADLALVGTNDADLVDEST
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 IGVAKPLPLSPEEGYVSAKEDSFLYPPHSCEEAGLADKPLFRADLALVGTNDADLVDEST
              790       800       810       820       830       840

              850       860       870       880       890       900
pF1KB0 FESPYSPENDSIYSTQASILSLHGSSCGDGLNYGSSLPSSPPKDVIENSCDPVLDLHMSL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 FESPYSPENDSIYSTQASILSLHGSSCGDGLNYGSSLPSSPPKDVIENSCDPVLDLHMSL
              850       860       870       880       890       900

              910       920       930       940       950       960
pF1KB0 EELYTQNLLQRQDENTPSVDISMGPASGFTINDYTPANAIEQQYECENTIVWTESHLPSE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 EELYTQNLLQRQDENTPSVDISMGPASGFTINDYTPANAIEQQYECENTIVWTESHLPSE
              910       920       930       940       950       960

              970       980       990      1000      1010      1020
pF1KB0 VISSAELPSVLPDSAGKGSEYLLEQSSLACNAECVMLQNVSKESFERTINIAKGNSSLGM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 VISSAELPSVLPDSAGKGSEYLLEQSSLACNAECVMLQNVSKESFERTINIAKGNSSLGM
              970       980       990      1000      1010      1020

             1030      1040      1050      1060      1070      1080
pF1KB0 TVSANKDGLGMIVRSIIHGGAISRDGRIAIGDCILSINEESTISVTNAQARAMLRRHSLI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 TVSANKDGLGMIVRSIIHGGAISRDGRIAIGDCILSINEESTISVTNAQARAMLRRHSLI
             1030      1040      1050      1060      1070      1080

             1090      1100      1110      1120      1130      1140
pF1KB0 GPDIKITYVPAEHLEEFKISLGQQSGRVMALDIFSSYTGRDIPELPEREEGEGEESELQN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 GPDIKITYVPAEHLEEFKISLGQQSGRVMALDIFSSYTGRDIPELPEREEGEGEESELQN
             1090      1100      1110      1120      1130      1140

             1150      1160      1170      1180      1190      1200
pF1KB0 TAYSNWNQPRRVELWREPSKSLGISIVGGRGMGSRLSNGEVMRGIFIKHVLEDSPAGKNG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 TAYSNWNQPRRVELWREPSKSLGISIVGGRGMGSRLSNGEVMRGIFIKHVLEDSPAGKNG
             1150      1160      1170      1180      1190      1200

             1210      1220      1230      1240      1250      1260
pF1KB0 TLKPGDRIVEVDGMDLRDASHEQAVEAIRKAGNPVVFMVQSIINRPRKSPLPSLLHNLYP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 TLKPGDRIVEVDGMDLRDASHEQAVEAIRKAGNPVVFMVQSIINRPRKSPLPSLLHNLYP
             1210      1220      1230      1240      1250      1260

             1270      1280      1290      1300      1310      1320
pF1KB0 KYNFSSTNPFADSLQINADKAPSQSESEPEKAPLCSVPPPPPSAFAEMGSDHTQSSASKI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 KYNFSSTNPFADSLQINADKAPSQSESEPEKAPLCSVPPPPPSAFAEMGSDHTQSSASKI
             1270      1280      1290      1300      1310      1320

             1330      1340      1350      1360      1370      1380
pF1KB0 SQDVDKEDEFGYSWKNIRERYGTLTGELHMIELEKGHSGLGLSLAGNKDRSRMSVFIVGI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 SQDVDKEDEFGYSWKNIRERYGTLTGELHMIELEKGHSGLGLSLAGNKDRSRMSVFIVGI
             1330      1340      1350      1360      1370      1380

             1390      1400      1410      1420      1430      1440
pF1KB0 DPNGAAGKDGRLQIADELLEINGQILYGRSHQNASSIIKCAPSKVKIIFIRNKDAVNQMA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 DPNGAAGKDGRLQIADELLEINGQILYGRSHQNASSIIKCAPSKVKIIFIRNKDAVNQMA
             1390      1400      1410      1420      1430      1440

             1450      1460      1470      1480      1490      1500
pF1KB0 VCPGNAVEPLPSNSENLQNKETEPTVTTSDAAVDLSSFKNVQHLELPKDQGGLGIAISEE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 VCPGNAVEPLPSNSENLQNKETEPTVTTSDAAVDLSSFKNVQHLELPKDQGGLGIAISEE
             1450      1460      1470      1480      1490      1500

             1510      1520      1530      1540      1550      1560
pF1KB0 DTLSGVIIKSLTEHGVAATDGRLKVGDQILAVDDEIVVGYPIEKFISLLKTAKMTVKLTI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 DTLSGVIIKSLTEHGVAATDGRLKVGDQILAVDDEIVVGYPIEKFISLLKTAKMTVKLTI
             1510      1520      1530      1540      1550      1560

             1570      1580      1590      1600      1610      1620
pF1KB0 HAENPDSQAVPSAAGAASGEKKNSSQSLMVPQSGSPEPESIRNTSRSSTPAIFASDPATC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 HAENPDSQAVPSAAGAASGEKKNSSQSLMVPQSGSPEPESIRNTSRSSTPAIFASDPATC
             1570      1580      1590      1600      1610      1620

             1630      1640      1650      1660      1670      1680
pF1KB0 PIIPGCETTIEISKGRTGLGLSIVGGSDTLLGAIIIHEVYEEGAACKDGRLWAGDQILEV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 PIIPGCETTIEISKGRTGLGLSIVGGSDTLLGAIIIHEVYEEGAACKDGRLWAGDQILEV
             1630      1640      1650      1660      1670      1680

             1690      1700      1710      1720      1730      1740
pF1KB0 NGIDLRKATHDEAINVLRQTPQRVRLTLYRDEAPYKEEEVCDTLTIELQKKPGKGLGLSI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 NGIDLRKATHDEAINVLRQTPQRVRLTLYRDEAPYKEEEVCDTLTIELQKKPGKGLGLSI
             1690      1700      1710      1720      1730      1740

             1750      1760      1770      1780      1790          
pF1KB0 VGKRNDTGVFVSDIVKGGIADADGRLMQGDQILMVNGEDVRNATQEAVAALLK-------
       :::::::::::::::::::::::::::::::::::::::::::::::::::::       
XP_006 VGKRNDTGVFVSDIVKGGIADADGRLMQGDQILMVNGEDVRNATQEAVAALLKCSLGTVT
             1750      1760      1770      1780      1790      1800

                                1800      1810      1820      1830 
pF1KB0 ----------------------VSEGSLSSFTFPLSGSSTSESLESSSKKNALASEIQGL
                             ::::::::::::::::::::::::::::::::::::::
XP_006 LEVGRIKAGPFHSERRPSQSSQVSEGSLSSFTFPLSGSSTSESLESSSKKNALASEIQGL
             1810      1820      1830      1840      1850      1860

            1840      1850      1860      1870      1880      1890 
pF1KB0 RTVEMKKGPTDSLGISIAGGVGSPLGDVPIFIAMMHPTGVAAQTQKLRVGDRIVTICGTS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 RTVEMKKGPTDSLGISIAGGVGSPLGDVPIFIAMMHPTGVAAQTQKLRVGDRIVTICGTS
             1870      1880      1890      1900      1910      1920

            1900      1910      1920      1930      1940      1950 
pF1KB0 TEGMTHTQAVNLLKNASGSIEMQVVAGGDVSVVTGHQQEPASSSLSFTGLTSSSIFQDDL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 TEGMTHTQAVNLLKNASGSIEMQVVAGGDVSVVTGHQQEPASSSLSFTGLTSSSIFQDDL
             1930      1940      1950      1960      1970      1980

            1960      1970      1980      1990      2000      2010 
pF1KB0 GPPQCKSITLERGPDGLGFSIVGGYGSPHGDLPIYVKTVFAKGAASEDGRLKRGDQIIAV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 GPPQCKSITLERGPDGLGFSIVGGYGSPHGDLPIYVKTVFAKGAASEDGRLKRGDQIIAV
             1990      2000      2010      2020      2030      2040

            2020      2030      2040 
pF1KB0 NGQSLEGVTHEEAVAILKRTKGTVTLMVLS
       ::::::::::::::::::::::::::::::
XP_006 NGQSLEGVTHEEAVAILKRTKGTVTLMVLS
             2050      2060      2070

>>XP_006716949 (OMIM: 603785,615219) PREDICTED: multiple  (2070 aa)
 initn: 11829 init1: 11606 opt: 11606  Z-score: 7909.9  bits: 1477.2 E(85289):    0
Smith-Waterman score: 13094; 98.6% identity (98.6% similar) in 2070 aa overlap (1-2041:1-2070)

               10        20        30        40        50        60
pF1KB0 MLEAIDKNRALHAAERLQTKLRERGDVANEDKLSLLKSVLQSPLFSQILSLQTSVQQLKD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 MLEAIDKNRALHAAERLQTKLRERGDVANEDKLSLLKSVLQSPLFSQILSLQTSVQQLKD
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB0 QVNIATSATSNIEYAHVPHLSPAVIPTLQNESFLLSPNNGNLEALTGPGIPHINGKPACD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 QVNIATSATSNIEYAHVPHLSPAVIPTLQNESFLLSPNNGNLEALTGPGIPHINGKPACD
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB0 EFDQLIKNMAQGRHVEVFELLKPPSGGLGFSVVGLRSENRGELGIFVQEIQEGSVAHRDG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 EFDQLIKNMAQGRHVEVFELLKPPSGGLGFSVVGLRSENRGELGIFVQEIQEGSVAHRDG
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB0 RLKETDQILAINGQALDQTITHQQAISILQKAKDTVQLVIARGSLPQLVSPIVSRSPSAA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 RLKETDQILAINGQALDQTITHQQAISILQKAKDTVQLVIARGSLPQLVSPIVSRSPSAA
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB0 STISAHSNPVHWQHMETIELVNDGSGLGFGIIGGKATGVIVKTILPGGVADQHGRLCSGD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 STISAHSNPVHWQHMETIELVNDGSGLGFGIIGGKATGVIVKTILPGGVADQHGRLCSGD
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB0 HILKIGDTDLAGMSSEQVAQVLRQCGNRVKLMIARGAIEERTAPTALGITLSSSPTSTPE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 HILKIGDTDLAGMSSEQVAQVLRQCGNRVKLMIARGAIEERTAPTALGITLSSSPTSTPE
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB0 LRVDASTQKGEESETFDVELTKNVQGLGITIAGYIGDKKLEPSGIFVKSITKSSAVEHDG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LRVDASTQKGEESETFDVELTKNVQGLGITIAGYIGDKKLEPSGIFVKSITKSSAVEHDG
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KB0 RIQIGDQIIAVDGTNLQGFTNQQAVEVLRHTGQTVLLTLMRRGMKQEAELMSREDVTKDA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 RIQIGDQIIAVDGTNLQGFTNQQAVEVLRHTGQTVLLTLMRRGMKQEAELMSREDVTKDA
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KB0 DLSPVNASIIKENYEKDEDFLSSTRNTNILPTEEEGYPLLSAEIEEIEDAQKQEAALLTK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 DLSPVNASIIKENYEKDEDFLSSTRNTNILPTEEEGYPLLSAEIEEIEDAQKQEAALLTK
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KB0 WQRIMGINYEIVVAHVSKFSENSGLGISLEATVGHHFIRSVLPEGPVGHSGKLFSGDELL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 WQRIMGINYEIVVAHVSKFSENSGLGISLEATVGHHFIRSVLPEGPVGHSGKLFSGDELL
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KB0 EVNGITLLGENHQDVVNILKELPIEVTMVCCRRTVPPTTQSELDSLDLCDIELTEKPHVD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 EVNGITLLGENHQDVVNILKELPIEVTMVCCRRTVPPTTQSELDSLDLCDIELTEKPHVD
              610       620       630       640       650       660

              670       680       690       700       710       720
pF1KB0 LGEFIGSSETEDPVLAMTDAGQSTEEVQAPLAMWEAGIQHIELEKGSKGLGFSILDYQDP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LGEFIGSSETEDPVLAMTDAGQSTEEVQAPLAMWEAGIQHIELEKGSKGLGFSILDYQDP
              670       680       690       700       710       720

              730       740       750       760       770       780
pF1KB0 IDPASTVIIIRSLVPGGIAEKDGRLLPGDRLMFVNDVNLENSSLEEAVEALKGAPSGTVR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 IDPASTVIIIRSLVPGGIAEKDGRLLPGDRLMFVNDVNLENSSLEEAVEALKGAPSGTVR
              730       740       750       760       770       780

              790       800       810       820       830       840
pF1KB0 IGVAKPLPLSPEEGYVSAKEDSFLYPPHSCEEAGLADKPLFRADLALVGTNDADLVDEST
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 IGVAKPLPLSPEEGYVSAKEDSFLYPPHSCEEAGLADKPLFRADLALVGTNDADLVDEST
              790       800       810       820       830       840

              850       860       870       880       890       900
pF1KB0 FESPYSPENDSIYSTQASILSLHGSSCGDGLNYGSSLPSSPPKDVIENSCDPVLDLHMSL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 FESPYSPENDSIYSTQASILSLHGSSCGDGLNYGSSLPSSPPKDVIENSCDPVLDLHMSL
              850       860       870       880       890       900

              910       920       930       940       950       960
pF1KB0 EELYTQNLLQRQDENTPSVDISMGPASGFTINDYTPANAIEQQYECENTIVWTESHLPSE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 EELYTQNLLQRQDENTPSVDISMGPASGFTINDYTPANAIEQQYECENTIVWTESHLPSE
              910       920       930       940       950       960

              970       980       990      1000      1010      1020
pF1KB0 VISSAELPSVLPDSAGKGSEYLLEQSSLACNAECVMLQNVSKESFERTINIAKGNSSLGM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 VISSAELPSVLPDSAGKGSEYLLEQSSLACNAECVMLQNVSKESFERTINIAKGNSSLGM
              970       980       990      1000      1010      1020

             1030      1040      1050      1060      1070      1080
pF1KB0 TVSANKDGLGMIVRSIIHGGAISRDGRIAIGDCILSINEESTISVTNAQARAMLRRHSLI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 TVSANKDGLGMIVRSIIHGGAISRDGRIAIGDCILSINEESTISVTNAQARAMLRRHSLI
             1030      1040      1050      1060      1070      1080

             1090      1100      1110      1120      1130      1140
pF1KB0 GPDIKITYVPAEHLEEFKISLGQQSGRVMALDIFSSYTGRDIPELPEREEGEGEESELQN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 GPDIKITYVPAEHLEEFKISLGQQSGRVMALDIFSSYTGRDIPELPEREEGEGEESELQN
             1090      1100      1110      1120      1130      1140

             1150      1160      1170      1180      1190      1200
pF1KB0 TAYSNWNQPRRVELWREPSKSLGISIVGGRGMGSRLSNGEVMRGIFIKHVLEDSPAGKNG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 TAYSNWNQPRRVELWREPSKSLGISIVGGRGMGSRLSNGEVMRGIFIKHVLEDSPAGKNG
             1150      1160      1170      1180      1190      1200

             1210      1220      1230      1240      1250      1260
pF1KB0 TLKPGDRIVEVDGMDLRDASHEQAVEAIRKAGNPVVFMVQSIINRPRKSPLPSLLHNLYP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 TLKPGDRIVEVDGMDLRDASHEQAVEAIRKAGNPVVFMVQSIINRPRKSPLPSLLHNLYP
             1210      1220      1230      1240      1250      1260

             1270      1280      1290      1300      1310      1320
pF1KB0 KYNFSSTNPFADSLQINADKAPSQSESEPEKAPLCSVPPPPPSAFAEMGSDHTQSSASKI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 KYNFSSTNPFADSLQINADKAPSQSESEPEKAPLCSVPPPPPSAFAEMGSDHTQSSASKI
             1270      1280      1290      1300      1310      1320

             1330      1340      1350      1360      1370      1380
pF1KB0 SQDVDKEDEFGYSWKNIRERYGTLTGELHMIELEKGHSGLGLSLAGNKDRSRMSVFIVGI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 SQDVDKEDEFGYSWKNIRERYGTLTGELHMIELEKGHSGLGLSLAGNKDRSRMSVFIVGI
             1330      1340      1350      1360      1370      1380

             1390      1400      1410      1420      1430      1440
pF1KB0 DPNGAAGKDGRLQIADELLEINGQILYGRSHQNASSIIKCAPSKVKIIFIRNKDAVNQMA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 DPNGAAGKDGRLQIADELLEINGQILYGRSHQNASSIIKCAPSKVKIIFIRNKDAVNQMA
             1390      1400      1410      1420      1430      1440

             1450      1460      1470      1480      1490      1500
pF1KB0 VCPGNAVEPLPSNSENLQNKETEPTVTTSDAAVDLSSFKNVQHLELPKDQGGLGIAISEE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 VCPGNAVEPLPSNSENLQNKETEPTVTTSDAAVDLSSFKNVQHLELPKDQGGLGIAISEE
             1450      1460      1470      1480      1490      1500

             1510      1520      1530      1540      1550      1560
pF1KB0 DTLSGVIIKSLTEHGVAATDGRLKVGDQILAVDDEIVVGYPIEKFISLLKTAKMTVKLTI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 DTLSGVIIKSLTEHGVAATDGRLKVGDQILAVDDEIVVGYPIEKFISLLKTAKMTVKLTI
             1510      1520      1530      1540      1550      1560

             1570      1580      1590      1600      1610      1620
pF1KB0 HAENPDSQAVPSAAGAASGEKKNSSQSLMVPQSGSPEPESIRNTSRSSTPAIFASDPATC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 HAENPDSQAVPSAAGAASGEKKNSSQSLMVPQSGSPEPESIRNTSRSSTPAIFASDPATC
             1570      1580      1590      1600      1610      1620

             1630      1640      1650      1660      1670      1680
pF1KB0 PIIPGCETTIEISKGRTGLGLSIVGGSDTLLGAIIIHEVYEEGAACKDGRLWAGDQILEV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 PIIPGCETTIEISKGRTGLGLSIVGGSDTLLGAIIIHEVYEEGAACKDGRLWAGDQILEV
             1630      1640      1650      1660      1670      1680

             1690      1700      1710      1720      1730      1740
pF1KB0 NGIDLRKATHDEAINVLRQTPQRVRLTLYRDEAPYKEEEVCDTLTIELQKKPGKGLGLSI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 NGIDLRKATHDEAINVLRQTPQRVRLTLYRDEAPYKEEEVCDTLTIELQKKPGKGLGLSI
             1690      1700      1710      1720      1730      1740

             1750      1760      1770      1780      1790          
pF1KB0 VGKRNDTGVFVSDIVKGGIADADGRLMQGDQILMVNGEDVRNATQEAVAALLK-------
       :::::::::::::::::::::::::::::::::::::::::::::::::::::       
XP_006 VGKRNDTGVFVSDIVKGGIADADGRLMQGDQILMVNGEDVRNATQEAVAALLKCSLGTVT
             1750      1760      1770      1780      1790      1800

                                1800      1810      1820      1830 
pF1KB0 ----------------------VSEGSLSSFTFPLSGSSTSESLESSSKKNALASEIQGL
                             ::::::::::::::::::::::::::::::::::::::
XP_006 LEVGRIKAGPFHSERRPSQSSQVSEGSLSSFTFPLSGSSTSESLESSSKKNALASEIQGL
             1810      1820      1830      1840      1850      1860

            1840      1850      1860      1870      1880      1890 
pF1KB0 RTVEMKKGPTDSLGISIAGGVGSPLGDVPIFIAMMHPTGVAAQTQKLRVGDRIVTICGTS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 RTVEMKKGPTDSLGISIAGGVGSPLGDVPIFIAMMHPTGVAAQTQKLRVGDRIVTICGTS
             1870      1880      1890      1900      1910      1920

            1900      1910      1920      1930      1940      1950 
pF1KB0 TEGMTHTQAVNLLKNASGSIEMQVVAGGDVSVVTGHQQEPASSSLSFTGLTSSSIFQDDL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 TEGMTHTQAVNLLKNASGSIEMQVVAGGDVSVVTGHQQEPASSSLSFTGLTSSSIFQDDL
             1930      1940      1950      1960      1970      1980

            1960      1970      1980      1990      2000      2010 
pF1KB0 GPPQCKSITLERGPDGLGFSIVGGYGSPHGDLPIYVKTVFAKGAASEDGRLKRGDQIIAV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 GPPQCKSITLERGPDGLGFSIVGGYGSPHGDLPIYVKTVFAKGAASEDGRLKRGDQIIAV
             1990      2000      2010      2020      2030      2040

            2020      2030      2040 
pF1KB0 NGQSLEGVTHEEAVAILKRTKGTVTLMVLS
       ::::::::::::::::::::::::::::::
XP_006 NGQSLEGVTHEEAVAILKRTKGTVTLMVLS
             2050      2060      2070

>>NP_001317566 (OMIM: 603785,615219) multiple PDZ domain  (2070 aa)
 initn: 11829 init1: 11606 opt: 11606  Z-score: 7909.9  bits: 1477.2 E(85289):    0
Smith-Waterman score: 13094; 98.6% identity (98.6% similar) in 2070 aa overlap (1-2041:1-2070)

               10        20        30        40        50        60
pF1KB0 MLEAIDKNRALHAAERLQTKLRERGDVANEDKLSLLKSVLQSPLFSQILSLQTSVQQLKD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MLEAIDKNRALHAAERLQTKLRERGDVANEDKLSLLKSVLQSPLFSQILSLQTSVQQLKD
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB0 QVNIATSATSNIEYAHVPHLSPAVIPTLQNESFLLSPNNGNLEALTGPGIPHINGKPACD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QVNIATSATSNIEYAHVPHLSPAVIPTLQNESFLLSPNNGNLEALTGPGIPHINGKPACD
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB0 EFDQLIKNMAQGRHVEVFELLKPPSGGLGFSVVGLRSENRGELGIFVQEIQEGSVAHRDG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EFDQLIKNMAQGRHVEVFELLKPPSGGLGFSVVGLRSENRGELGIFVQEIQEGSVAHRDG
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB0 RLKETDQILAINGQALDQTITHQQAISILQKAKDTVQLVIARGSLPQLVSPIVSRSPSAA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RLKETDQILAINGQALDQTITHQQAISILQKAKDTVQLVIARGSLPQLVSPIVSRSPSAA
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB0 STISAHSNPVHWQHMETIELVNDGSGLGFGIIGGKATGVIVKTILPGGVADQHGRLCSGD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 STISAHSNPVHWQHMETIELVNDGSGLGFGIIGGKATGVIVKTILPGGVADQHGRLCSGD
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB0 HILKIGDTDLAGMSSEQVAQVLRQCGNRVKLMIARGAIEERTAPTALGITLSSSPTSTPE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HILKIGDTDLAGMSSEQVAQVLRQCGNRVKLMIARGAIEERTAPTALGITLSSSPTSTPE
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB0 LRVDASTQKGEESETFDVELTKNVQGLGITIAGYIGDKKLEPSGIFVKSITKSSAVEHDG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LRVDASTQKGEESETFDVELTKNVQGLGITIAGYIGDKKLEPSGIFVKSITKSSAVEHDG
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KB0 RIQIGDQIIAVDGTNLQGFTNQQAVEVLRHTGQTVLLTLMRRGMKQEAELMSREDVTKDA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RIQIGDQIIAVDGTNLQGFTNQQAVEVLRHTGQTVLLTLMRRGMKQEAELMSREDVTKDA
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KB0 DLSPVNASIIKENYEKDEDFLSSTRNTNILPTEEEGYPLLSAEIEEIEDAQKQEAALLTK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DLSPVNASIIKENYEKDEDFLSSTRNTNILPTEEEGYPLLSAEIEEIEDAQKQEAALLTK
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KB0 WQRIMGINYEIVVAHVSKFSENSGLGISLEATVGHHFIRSVLPEGPVGHSGKLFSGDELL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 WQRIMGINYEIVVAHVSKFSENSGLGISLEATVGHHFIRSVLPEGPVGHSGKLFSGDELL
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KB0 EVNGITLLGENHQDVVNILKELPIEVTMVCCRRTVPPTTQSELDSLDLCDIELTEKPHVD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EVNGITLLGENHQDVVNILKELPIEVTMVCCRRTVPPTTQSELDSLDLCDIELTEKPHVD
              610       620       630       640       650       660

              670       680       690       700       710       720
pF1KB0 LGEFIGSSETEDPVLAMTDAGQSTEEVQAPLAMWEAGIQHIELEKGSKGLGFSILDYQDP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LGEFIGSSETEDPVLAMTDAGQSTEEVQAPLAMWEAGIQHIELEKGSKGLGFSILDYQDP
              670       680       690       700       710       720

              730       740       750       760       770       780
pF1KB0 IDPASTVIIIRSLVPGGIAEKDGRLLPGDRLMFVNDVNLENSSLEEAVEALKGAPSGTVR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IDPASTVIIIRSLVPGGIAEKDGRLLPGDRLMFVNDVNLENSSLEEAVEALKGAPSGTVR
              730       740       750       760       770       780

              790       800       810       820       830       840
pF1KB0 IGVAKPLPLSPEEGYVSAKEDSFLYPPHSCEEAGLADKPLFRADLALVGTNDADLVDEST
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IGVAKPLPLSPEEGYVSAKEDSFLYPPHSCEEAGLADKPLFRADLALVGTNDADLVDEST
              790       800       810       820       830       840

              850       860       870       880       890       900
pF1KB0 FESPYSPENDSIYSTQASILSLHGSSCGDGLNYGSSLPSSPPKDVIENSCDPVLDLHMSL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FESPYSPENDSIYSTQASILSLHGSSCGDGLNYGSSLPSSPPKDVIENSCDPVLDLHMSL
              850       860       870       880       890       900

              910       920       930       940       950       960
pF1KB0 EELYTQNLLQRQDENTPSVDISMGPASGFTINDYTPANAIEQQYECENTIVWTESHLPSE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EELYTQNLLQRQDENTPSVDISMGPASGFTINDYTPANAIEQQYECENTIVWTESHLPSE
              910       920       930       940       950       960

              970       980       990      1000      1010      1020
pF1KB0 VISSAELPSVLPDSAGKGSEYLLEQSSLACNAECVMLQNVSKESFERTINIAKGNSSLGM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VISSAELPSVLPDSAGKGSEYLLEQSSLACNAECVMLQNVSKESFERTINIAKGNSSLGM
              970       980       990      1000      1010      1020

             1030      1040      1050      1060      1070      1080
pF1KB0 TVSANKDGLGMIVRSIIHGGAISRDGRIAIGDCILSINEESTISVTNAQARAMLRRHSLI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TVSANKDGLGMIVRSIIHGGAISRDGRIAIGDCILSINEESTISVTNAQARAMLRRHSLI
             1030      1040      1050      1060      1070      1080

             1090      1100      1110      1120      1130      1140
pF1KB0 GPDIKITYVPAEHLEEFKISLGQQSGRVMALDIFSSYTGRDIPELPEREEGEGEESELQN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GPDIKITYVPAEHLEEFKISLGQQSGRVMALDIFSSYTGRDIPELPEREEGEGEESELQN
             1090      1100      1110      1120      1130      1140

             1150      1160      1170      1180      1190      1200
pF1KB0 TAYSNWNQPRRVELWREPSKSLGISIVGGRGMGSRLSNGEVMRGIFIKHVLEDSPAGKNG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TAYSNWNQPRRVELWREPSKSLGISIVGGRGMGSRLSNGEVMRGIFIKHVLEDSPAGKNG
             1150      1160      1170      1180      1190      1200

             1210      1220      1230      1240      1250      1260
pF1KB0 TLKPGDRIVEVDGMDLRDASHEQAVEAIRKAGNPVVFMVQSIINRPRKSPLPSLLHNLYP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TLKPGDRIVEVDGMDLRDASHEQAVEAIRKAGNPVVFMVQSIINRPRKSPLPSLLHNLYP
             1210      1220      1230      1240      1250      1260

             1270      1280      1290      1300      1310      1320
pF1KB0 KYNFSSTNPFADSLQINADKAPSQSESEPEKAPLCSVPPPPPSAFAEMGSDHTQSSASKI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KYNFSSTNPFADSLQINADKAPSQSESEPEKAPLCSVPPPPPSAFAEMGSDHTQSSASKI
             1270      1280      1290      1300      1310      1320

             1330      1340      1350      1360      1370      1380
pF1KB0 SQDVDKEDEFGYSWKNIRERYGTLTGELHMIELEKGHSGLGLSLAGNKDRSRMSVFIVGI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SQDVDKEDEFGYSWKNIRERYGTLTGELHMIELEKGHSGLGLSLAGNKDRSRMSVFIVGI
             1330      1340      1350      1360      1370      1380

             1390      1400      1410      1420      1430      1440
pF1KB0 DPNGAAGKDGRLQIADELLEINGQILYGRSHQNASSIIKCAPSKVKIIFIRNKDAVNQMA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DPNGAAGKDGRLQIADELLEINGQILYGRSHQNASSIIKCAPSKVKIIFIRNKDAVNQMA
             1390      1400      1410      1420      1430      1440

             1450      1460      1470      1480      1490      1500
pF1KB0 VCPGNAVEPLPSNSENLQNKETEPTVTTSDAAVDLSSFKNVQHLELPKDQGGLGIAISEE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VCPGNAVEPLPSNSENLQNKETEPTVTTSDAAVDLSSFKNVQHLELPKDQGGLGIAISEE
             1450      1460      1470      1480      1490      1500

             1510      1520      1530      1540      1550      1560
pF1KB0 DTLSGVIIKSLTEHGVAATDGRLKVGDQILAVDDEIVVGYPIEKFISLLKTAKMTVKLTI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DTLSGVIIKSLTEHGVAATDGRLKVGDQILAVDDEIVVGYPIEKFISLLKTAKMTVKLTI
             1510      1520      1530      1540      1550      1560

             1570      1580      1590      1600      1610      1620
pF1KB0 HAENPDSQAVPSAAGAASGEKKNSSQSLMVPQSGSPEPESIRNTSRSSTPAIFASDPATC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HAENPDSQAVPSAAGAASGEKKNSSQSLMVPQSGSPEPESIRNTSRSSTPAIFASDPATC
             1570      1580      1590      1600      1610      1620

             1630      1640      1650      1660      1670      1680
pF1KB0 PIIPGCETTIEISKGRTGLGLSIVGGSDTLLGAIIIHEVYEEGAACKDGRLWAGDQILEV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PIIPGCETTIEISKGRTGLGLSIVGGSDTLLGAIIIHEVYEEGAACKDGRLWAGDQILEV
             1630      1640      1650      1660      1670      1680

             1690      1700      1710      1720      1730      1740
pF1KB0 NGIDLRKATHDEAINVLRQTPQRVRLTLYRDEAPYKEEEVCDTLTIELQKKPGKGLGLSI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NGIDLRKATHDEAINVLRQTPQRVRLTLYRDEAPYKEEEVCDTLTIELQKKPGKGLGLSI
             1690      1700      1710      1720      1730      1740

             1750      1760      1770      1780      1790          
pF1KB0 VGKRNDTGVFVSDIVKGGIADADGRLMQGDQILMVNGEDVRNATQEAVAALLK-------
       :::::::::::::::::::::::::::::::::::::::::::::::::::::       
NP_001 VGKRNDTGVFVSDIVKGGIADADGRLMQGDQILMVNGEDVRNATQEAVAALLKCSLGTVT
             1750      1760      1770      1780      1790      1800

                                1800      1810      1820      1830 
pF1KB0 ----------------------VSEGSLSSFTFPLSGSSTSESLESSSKKNALASEIQGL
                             ::::::::::::::::::::::::::::::::::::::
NP_001 LEVGRIKAGPFHSERRPSQSSQVSEGSLSSFTFPLSGSSTSESLESSSKKNALASEIQGL
             1810      1820      1830      1840      1850      1860

            1840      1850      1860      1870      1880      1890 
pF1KB0 RTVEMKKGPTDSLGISIAGGVGSPLGDVPIFIAMMHPTGVAAQTQKLRVGDRIVTICGTS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RTVEMKKGPTDSLGISIAGGVGSPLGDVPIFIAMMHPTGVAAQTQKLRVGDRIVTICGTS
             1870      1880      1890      1900      1910      1920

            1900      1910      1920      1930      1940      1950 
pF1KB0 TEGMTHTQAVNLLKNASGSIEMQVVAGGDVSVVTGHQQEPASSSLSFTGLTSSSIFQDDL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TEGMTHTQAVNLLKNASGSIEMQVVAGGDVSVVTGHQQEPASSSLSFTGLTSSSIFQDDL
             1930      1940      1950      1960      1970      1980

            1960      1970      1980      1990      2000      2010 
pF1KB0 GPPQCKSITLERGPDGLGFSIVGGYGSPHGDLPIYVKTVFAKGAASEDGRLKRGDQIIAV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GPPQCKSITLERGPDGLGFSIVGGYGSPHGDLPIYVKTVFAKGAASEDGRLKRGDQIIAV
             1990      2000      2010      2020      2030      2040

            2020      2030      2040 
pF1KB0 NGQSLEGVTHEEAVAILKRTKGTVTLMVLS
       ::::::::::::::::::::::::::::::
NP_001 NGQSLEGVTHEEAVAILKRTKGTVTLMVLS
             2050      2060      2070

>>XP_016870747 (OMIM: 603785,615219) PREDICTED: multiple  (1461 aa)
 initn: 9478 init1: 9478 opt: 9478  Z-score: 6463.3  bits: 1209.0 E(85289):    0
Smith-Waterman score: 9478; 100.0% identity (100.0% similar) in 1461 aa overlap (1-1461:1-1461)

               10        20        30        40        50        60
pF1KB0 MLEAIDKNRALHAAERLQTKLRERGDVANEDKLSLLKSVLQSPLFSQILSLQTSVQQLKD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MLEAIDKNRALHAAERLQTKLRERGDVANEDKLSLLKSVLQSPLFSQILSLQTSVQQLKD
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB0 QVNIATSATSNIEYAHVPHLSPAVIPTLQNESFLLSPNNGNLEALTGPGIPHINGKPACD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QVNIATSATSNIEYAHVPHLSPAVIPTLQNESFLLSPNNGNLEALTGPGIPHINGKPACD
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB0 EFDQLIKNMAQGRHVEVFELLKPPSGGLGFSVVGLRSENRGELGIFVQEIQEGSVAHRDG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EFDQLIKNMAQGRHVEVFELLKPPSGGLGFSVVGLRSENRGELGIFVQEIQEGSVAHRDG
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB0 RLKETDQILAINGQALDQTITHQQAISILQKAKDTVQLVIARGSLPQLVSPIVSRSPSAA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RLKETDQILAINGQALDQTITHQQAISILQKAKDTVQLVIARGSLPQLVSPIVSRSPSAA
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB0 STISAHSNPVHWQHMETIELVNDGSGLGFGIIGGKATGVIVKTILPGGVADQHGRLCSGD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 STISAHSNPVHWQHMETIELVNDGSGLGFGIIGGKATGVIVKTILPGGVADQHGRLCSGD
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB0 HILKIGDTDLAGMSSEQVAQVLRQCGNRVKLMIARGAIEERTAPTALGITLSSSPTSTPE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HILKIGDTDLAGMSSEQVAQVLRQCGNRVKLMIARGAIEERTAPTALGITLSSSPTSTPE
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB0 LRVDASTQKGEESETFDVELTKNVQGLGITIAGYIGDKKLEPSGIFVKSITKSSAVEHDG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LRVDASTQKGEESETFDVELTKNVQGLGITIAGYIGDKKLEPSGIFVKSITKSSAVEHDG
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KB0 RIQIGDQIIAVDGTNLQGFTNQQAVEVLRHTGQTVLLTLMRRGMKQEAELMSREDVTKDA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RIQIGDQIIAVDGTNLQGFTNQQAVEVLRHTGQTVLLTLMRRGMKQEAELMSREDVTKDA
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KB0 DLSPVNASIIKENYEKDEDFLSSTRNTNILPTEEEGYPLLSAEIEEIEDAQKQEAALLTK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DLSPVNASIIKENYEKDEDFLSSTRNTNILPTEEEGYPLLSAEIEEIEDAQKQEAALLTK
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KB0 WQRIMGINYEIVVAHVSKFSENSGLGISLEATVGHHFIRSVLPEGPVGHSGKLFSGDELL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 WQRIMGINYEIVVAHVSKFSENSGLGISLEATVGHHFIRSVLPEGPVGHSGKLFSGDELL
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KB0 EVNGITLLGENHQDVVNILKELPIEVTMVCCRRTVPPTTQSELDSLDLCDIELTEKPHVD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EVNGITLLGENHQDVVNILKELPIEVTMVCCRRTVPPTTQSELDSLDLCDIELTEKPHVD
              610       620       630       640       650       660

              670       680       690       700       710       720
pF1KB0 LGEFIGSSETEDPVLAMTDAGQSTEEVQAPLAMWEAGIQHIELEKGSKGLGFSILDYQDP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LGEFIGSSETEDPVLAMTDAGQSTEEVQAPLAMWEAGIQHIELEKGSKGLGFSILDYQDP
              670       680       690       700       710       720

              730       740       750       760       770       780
pF1KB0 IDPASTVIIIRSLVPGGIAEKDGRLLPGDRLMFVNDVNLENSSLEEAVEALKGAPSGTVR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IDPASTVIIIRSLVPGGIAEKDGRLLPGDRLMFVNDVNLENSSLEEAVEALKGAPSGTVR
              730       740       750       760       770       780

              790       800       810       820       830       840
pF1KB0 IGVAKPLPLSPEEGYVSAKEDSFLYPPHSCEEAGLADKPLFRADLALVGTNDADLVDEST
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IGVAKPLPLSPEEGYVSAKEDSFLYPPHSCEEAGLADKPLFRADLALVGTNDADLVDEST
              790       800       810       820       830       840

              850       860       870       880       890       900
pF1KB0 FESPYSPENDSIYSTQASILSLHGSSCGDGLNYGSSLPSSPPKDVIENSCDPVLDLHMSL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FESPYSPENDSIYSTQASILSLHGSSCGDGLNYGSSLPSSPPKDVIENSCDPVLDLHMSL
              850       860       870       880       890       900

              910       920       930       940       950       960
pF1KB0 EELYTQNLLQRQDENTPSVDISMGPASGFTINDYTPANAIEQQYECENTIVWTESHLPSE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EELYTQNLLQRQDENTPSVDISMGPASGFTINDYTPANAIEQQYECENTIVWTESHLPSE
              910       920       930       940       950       960

              970       980       990      1000      1010      1020
pF1KB0 VISSAELPSVLPDSAGKGSEYLLEQSSLACNAECVMLQNVSKESFERTINIAKGNSSLGM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VISSAELPSVLPDSAGKGSEYLLEQSSLACNAECVMLQNVSKESFERTINIAKGNSSLGM
              970       980       990      1000      1010      1020

             1030      1040      1050      1060      1070      1080
pF1KB0 TVSANKDGLGMIVRSIIHGGAISRDGRIAIGDCILSINEESTISVTNAQARAMLRRHSLI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TVSANKDGLGMIVRSIIHGGAISRDGRIAIGDCILSINEESTISVTNAQARAMLRRHSLI
             1030      1040      1050      1060      1070      1080

             1090      1100      1110      1120      1130      1140
pF1KB0 GPDIKITYVPAEHLEEFKISLGQQSGRVMALDIFSSYTGRDIPELPEREEGEGEESELQN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GPDIKITYVPAEHLEEFKISLGQQSGRVMALDIFSSYTGRDIPELPEREEGEGEESELQN
             1090      1100      1110      1120      1130      1140

             1150      1160      1170      1180      1190      1200
pF1KB0 TAYSNWNQPRRVELWREPSKSLGISIVGGRGMGSRLSNGEVMRGIFIKHVLEDSPAGKNG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TAYSNWNQPRRVELWREPSKSLGISIVGGRGMGSRLSNGEVMRGIFIKHVLEDSPAGKNG
             1150      1160      1170      1180      1190      1200

             1210      1220      1230      1240      1250      1260
pF1KB0 TLKPGDRIVEVDGMDLRDASHEQAVEAIRKAGNPVVFMVQSIINRPRKSPLPSLLHNLYP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TLKPGDRIVEVDGMDLRDASHEQAVEAIRKAGNPVVFMVQSIINRPRKSPLPSLLHNLYP
             1210      1220      1230      1240      1250      1260

             1270      1280      1290      1300      1310      1320
pF1KB0 KYNFSSTNPFADSLQINADKAPSQSESEPEKAPLCSVPPPPPSAFAEMGSDHTQSSASKI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KYNFSSTNPFADSLQINADKAPSQSESEPEKAPLCSVPPPPPSAFAEMGSDHTQSSASKI
             1270      1280      1290      1300      1310      1320

             1330      1340      1350      1360      1370      1380
pF1KB0 SQDVDKEDEFGYSWKNIRERYGTLTGELHMIELEKGHSGLGLSLAGNKDRSRMSVFIVGI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SQDVDKEDEFGYSWKNIRERYGTLTGELHMIELEKGHSGLGLSLAGNKDRSRMSVFIVGI
             1330      1340      1350      1360      1370      1380

             1390      1400      1410      1420      1430      1440
pF1KB0 DPNGAAGKDGRLQIADELLEINGQILYGRSHQNASSIIKCAPSKVKIIFIRNKDAVNQMA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DPNGAAGKDGRLQIADELLEINGQILYGRSHQNASSIIKCAPSKVKIIFIRNKDAVNQMA
             1390      1400      1410      1420      1430      1440

             1450      1460      1470      1480      1490      1500
pF1KB0 VCPGNAVEPLPSNSENLQNKETEPTVTTSDAAVDLSSFKNVQHLELPKDQGGLGIAISEE
       :::::::::::::::::::::                                       
XP_016 VCPGNAVEPLPSNSENLQNKE                                       
             1450      1460                                        

>>NP_001248335 (OMIM: 603785,615219) multiple PDZ domain  (2037 aa)
 initn: 9815 init1: 8053 opt: 9434  Z-score: 6431.5  bits: 1203.6 E(85289):    0
Smith-Waterman score: 12797; 97.0% identity (97.0% similar) in 2070 aa overlap (1-2041:1-2037)

               10        20        30        40        50        60
pF1KB0 MLEAIDKNRALHAAERLQTKLRERGDVANEDKLSLLKSVLQSPLFSQILSLQTSVQQLKD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MLEAIDKNRALHAAERLQTKLRERGDVANEDKLSLLKSVLQSPLFSQILSLQTSVQQLKD
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB0 QVNIATSATSNIEYAHVPHLSPAVIPTLQNESFLLSPNNGNLEALTGPGIPHINGKPACD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QVNIATSATSNIEYAHVPHLSPAVIPTLQNESFLLSPNNGNLEALTGPGIPHINGKPACD
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB0 EFDQLIKNMAQGRHVEVFELLKPPSGGLGFSVVGLRSENRGELGIFVQEIQEGSVAHRDG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EFDQLIKNMAQGRHVEVFELLKPPSGGLGFSVVGLRSENRGELGIFVQEIQEGSVAHRDG
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB0 RLKETDQILAINGQALDQTITHQQAISILQKAKDTVQLVIARGSLPQLVSPIVSRSPSAA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RLKETDQILAINGQALDQTITHQQAISILQKAKDTVQLVIARGSLPQLVSPIVSRSPSAA
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB0 STISAHSNPVHWQHMETIELVNDGSGLGFGIIGGKATGVIVKTILPGGVADQHGRLCSGD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 STISAHSNPVHWQHMETIELVNDGSGLGFGIIGGKATGVIVKTILPGGVADQHGRLCSGD
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB0 HILKIGDTDLAGMSSEQVAQVLRQCGNRVKLMIARGAIEERTAPTALGITLSSSPTSTPE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HILKIGDTDLAGMSSEQVAQVLRQCGNRVKLMIARGAIEERTAPTALGITLSSSPTSTPE
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB0 LRVDASTQKGEESETFDVELTKNVQGLGITIAGYIGDKKLEPSGIFVKSITKSSAVEHDG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LRVDASTQKGEESETFDVELTKNVQGLGITIAGYIGDKKLEPSGIFVKSITKSSAVEHDG
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KB0 RIQIGDQIIAVDGTNLQGFTNQQAVEVLRHTGQTVLLTLMRRGMKQEAELMSREDVTKDA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RIQIGDQIIAVDGTNLQGFTNQQAVEVLRHTGQTVLLTLMRRGMKQEAELMSREDVTKDA
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KB0 DLSPVNASIIKENYEKDEDFLSSTRNTNILPTEEEGYPLLSAEIEEIEDAQKQEAALLTK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DLSPVNASIIKENYEKDEDFLSSTRNTNILPTEEEGYPLLSAEIEEIEDAQKQEAALLTK
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KB0 WQRIMGINYEIVVAHVSKFSENSGLGISLEATVGHHFIRSVLPEGPVGHSGKLFSGDELL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 WQRIMGINYEIVVAHVSKFSENSGLGISLEATVGHHFIRSVLPEGPVGHSGKLFSGDELL
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KB0 EVNGITLLGENHQDVVNILKELPIEVTMVCCRRTVPPTTQSELDSLDLCDIELTEKPHVD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EVNGITLLGENHQDVVNILKELPIEVTMVCCRRTVPPTTQSELDSLDLCDIELTEKPHVD
              610       620       630       640       650       660

              670       680       690       700       710       720
pF1KB0 LGEFIGSSETEDPVLAMTDAGQSTEEVQAPLAMWEAGIQHIELEKGSKGLGFSILDYQDP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LGEFIGSSETEDPVLAMTDAGQSTEEVQAPLAMWEAGIQHIELEKGSKGLGFSILDYQDP
              670       680       690       700       710       720

              730       740       750       760       770       780
pF1KB0 IDPASTVIIIRSLVPGGIAEKDGRLLPGDRLMFVNDVNLENSSLEEAVEALKGAPSGTVR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IDPASTVIIIRSLVPGGIAEKDGRLLPGDRLMFVNDVNLENSSLEEAVEALKGAPSGTVR
              730       740       750       760       770       780

              790       800       810       820       830       840
pF1KB0 IGVAKPLPLSPEEGYVSAKEDSFLYPPHSCEEAGLADKPLFRADLALVGTNDADLVDEST
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IGVAKPLPLSPEEGYVSAKEDSFLYPPHSCEEAGLADKPLFRADLALVGTNDADLVDEST
              790       800       810       820       830       840

              850       860       870       880       890       900
pF1KB0 FESPYSPENDSIYSTQASILSLHGSSCGDGLNYGSSLPSSPPKDVIENSCDPVLDLHMSL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FESPYSPENDSIYSTQASILSLHGSSCGDGLNYGSSLPSSPPKDVIENSCDPVLDLHMSL
              850       860       870       880       890       900

              910       920       930       940       950       960
pF1KB0 EELYTQNLLQRQDENTPSVDISMGPASGFTINDYTPANAIEQQYECENTIVWTESHLPSE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EELYTQNLLQRQDENTPSVDISMGPASGFTINDYTPANAIEQQYECENTIVWTESHLPSE
              910       920       930       940       950       960

              970       980       990      1000      1010      1020
pF1KB0 VISSAELPSVLPDSAGKGSEYLLEQSSLACNAECVMLQNVSKESFERTINIAKGNSSLGM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VISSAELPSVLPDSAGKGSEYLLEQSSLACNAECVMLQNVSKESFERTINIAKGNSSLGM
              970       980       990      1000      1010      1020

             1030      1040      1050      1060      1070      1080
pF1KB0 TVSANKDGLGMIVRSIIHGGAISRDGRIAIGDCILSINEESTISVTNAQARAMLRRHSLI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TVSANKDGLGMIVRSIIHGGAISRDGRIAIGDCILSINEESTISVTNAQARAMLRRHSLI
             1030      1040      1050      1060      1070      1080

             1090      1100      1110      1120      1130      1140
pF1KB0 GPDIKITYVPAEHLEEFKISLGQQSGRVMALDIFSSYTGRDIPELPEREEGEGEESELQN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GPDIKITYVPAEHLEEFKISLGQQSGRVMALDIFSSYTGRDIPELPEREEGEGEESELQN
             1090      1100      1110      1120      1130      1140

             1150      1160      1170      1180      1190      1200
pF1KB0 TAYSNWNQPRRVELWREPSKSLGISIVGGRGMGSRLSNGEVMRGIFIKHVLEDSPAGKNG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TAYSNWNQPRRVELWREPSKSLGISIVGGRGMGSRLSNGEVMRGIFIKHVLEDSPAGKNG
             1150      1160      1170      1180      1190      1200

             1210      1220      1230      1240      1250      1260
pF1KB0 TLKPGDRIVEVDGMDLRDASHEQAVEAIRKAGNPVVFMVQSIINRPRKSPLPSLLHNLYP
       :::::::::::::::::::::::::::::::::::::::::::::::             
NP_001 TLKPGDRIVEVDGMDLRDASHEQAVEAIRKAGNPVVFMVQSIINRPR-------------
             1210      1220      1230      1240                    

             1270      1280      1290      1300      1310      1320
pF1KB0 KYNFSSTNPFADSLQINADKAPSQSESEPEKAPLCSVPPPPPSAFAEMGSDHTQSSASKI
                           ::::::::::::::::::::::::::::::::::::::::
NP_001 --------------------APSQSESEPEKAPLCSVPPPPPSAFAEMGSDHTQSSASKI
                          1250      1260      1270      1280       

             1330      1340      1350      1360      1370      1380
pF1KB0 SQDVDKEDEFGYSWKNIRERYGTLTGELHMIELEKGHSGLGLSLAGNKDRSRMSVFIVGI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SQDVDKEDEFGYSWKNIRERYGTLTGELHMIELEKGHSGLGLSLAGNKDRSRMSVFIVGI
      1290      1300      1310      1320      1330      1340       

             1390      1400      1410      1420      1430      1440
pF1KB0 DPNGAAGKDGRLQIADELLEINGQILYGRSHQNASSIIKCAPSKVKIIFIRNKDAVNQMA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DPNGAAGKDGRLQIADELLEINGQILYGRSHQNASSIIKCAPSKVKIIFIRNKDAVNQMA
      1350      1360      1370      1380      1390      1400       

             1450      1460      1470      1480      1490      1500
pF1KB0 VCPGNAVEPLPSNSENLQNKETEPTVTTSDAAVDLSSFKNVQHLELPKDQGGLGIAISEE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VCPGNAVEPLPSNSENLQNKETEPTVTTSDAAVDLSSFKNVQHLELPKDQGGLGIAISEE
      1410      1420      1430      1440      1450      1460       

             1510      1520      1530      1540      1550      1560
pF1KB0 DTLSGVIIKSLTEHGVAATDGRLKVGDQILAVDDEIVVGYPIEKFISLLKTAKMTVKLTI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DTLSGVIIKSLTEHGVAATDGRLKVGDQILAVDDEIVVGYPIEKFISLLKTAKMTVKLTI
      1470      1480      1490      1500      1510      1520       

             1570      1580      1590      1600      1610      1620
pF1KB0 HAENPDSQAVPSAAGAASGEKKNSSQSLMVPQSGSPEPESIRNTSRSSTPAIFASDPATC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HAENPDSQAVPSAAGAASGEKKNSSQSLMVPQSGSPEPESIRNTSRSSTPAIFASDPATC
      1530      1540      1550      1560      1570      1580       

             1630      1640      1650      1660      1670      1680
pF1KB0 PIIPGCETTIEISKGRTGLGLSIVGGSDTLLGAIIIHEVYEEGAACKDGRLWAGDQILEV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PIIPGCETTIEISKGRTGLGLSIVGGSDTLLGAIIIHEVYEEGAACKDGRLWAGDQILEV
      1590      1600      1610      1620      1630      1640       

             1690      1700      1710      1720      1730      1740
pF1KB0 NGIDLRKATHDEAINVLRQTPQRVRLTLYRDEAPYKEEEVCDTLTIELQKKPGKGLGLSI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NGIDLRKATHDEAINVLRQTPQRVRLTLYRDEAPYKEEEVCDTLTIELQKKPGKGLGLSI
      1650      1660      1670      1680      1690      1700       

             1750      1760      1770      1780      1790          
pF1KB0 VGKRNDTGVFVSDIVKGGIADADGRLMQGDQILMVNGEDVRNATQEAVAALLK-------
       :::::::::::::::::::::::::::::::::::::::::::::::::::::       
NP_001 VGKRNDTGVFVSDIVKGGIADADGRLMQGDQILMVNGEDVRNATQEAVAALLKCSLGTVT
      1710      1720      1730      1740      1750      1760       

                                1800      1810      1820      1830 
pF1KB0 ----------------------VSEGSLSSFTFPLSGSSTSESLESSSKKNALASEIQGL
                             ::::::::::::::::::::::::::::::::::::::
NP_001 LEVGRIKAGPFHSERRPSQSSQVSEGSLSSFTFPLSGSSTSESLESSSKKNALASEIQGL
      1770      1780      1790      1800      1810      1820       

            1840      1850      1860      1870      1880      1890 
pF1KB0 RTVEMKKGPTDSLGISIAGGVGSPLGDVPIFIAMMHPTGVAAQTQKLRVGDRIVTICGTS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RTVEMKKGPTDSLGISIAGGVGSPLGDVPIFIAMMHPTGVAAQTQKLRVGDRIVTICGTS
      1830      1840      1850      1860      1870      1880       

            1900      1910      1920      1930      1940      1950 
pF1KB0 TEGMTHTQAVNLLKNASGSIEMQVVAGGDVSVVTGHQQEPASSSLSFTGLTSSSIFQDDL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TEGMTHTQAVNLLKNASGSIEMQVVAGGDVSVVTGHQQEPASSSLSFTGLTSSSIFQDDL
      1890      1900      1910      1920      1930      1940       

            1960      1970      1980      1990      2000      2010 
pF1KB0 GPPQCKSITLERGPDGLGFSIVGGYGSPHGDLPIYVKTVFAKGAASEDGRLKRGDQIIAV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GPPQCKSITLERGPDGLGFSIVGGYGSPHGDLPIYVKTVFAKGAASEDGRLKRGDQIIAV
      1950      1960      1970      1980      1990      2000       

            2020      2030      2040 
pF1KB0 NGQSLEGVTHEEAVAILKRTKGTVTLMVLS
       ::::::::::::::::::::::::::::::
NP_001 NGQSLEGVTHEEAVAILKRTKGTVTLMVLS
      2010      2020      2030       

>>XP_006716952 (OMIM: 603785,615219) PREDICTED: multiple  (2037 aa)
 initn: 9815 init1: 8053 opt: 9434  Z-score: 6431.5  bits: 1203.6 E(85289):    0
Smith-Waterman score: 12797; 97.0% identity (97.0% similar) in 2070 aa overlap (1-2041:1-2037)

               10        20        30        40        50        60
pF1KB0 MLEAIDKNRALHAAERLQTKLRERGDVANEDKLSLLKSVLQSPLFSQILSLQTSVQQLKD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 MLEAIDKNRALHAAERLQTKLRERGDVANEDKLSLLKSVLQSPLFSQILSLQTSVQQLKD
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB0 QVNIATSATSNIEYAHVPHLSPAVIPTLQNESFLLSPNNGNLEALTGPGIPHINGKPACD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 QVNIATSATSNIEYAHVPHLSPAVIPTLQNESFLLSPNNGNLEALTGPGIPHINGKPACD
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB0 EFDQLIKNMAQGRHVEVFELLKPPSGGLGFSVVGLRSENRGELGIFVQEIQEGSVAHRDG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 EFDQLIKNMAQGRHVEVFELLKPPSGGLGFSVVGLRSENRGELGIFVQEIQEGSVAHRDG
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB0 RLKETDQILAINGQALDQTITHQQAISILQKAKDTVQLVIARGSLPQLVSPIVSRSPSAA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 RLKETDQILAINGQALDQTITHQQAISILQKAKDTVQLVIARGSLPQLVSPIVSRSPSAA
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB0 STISAHSNPVHWQHMETIELVNDGSGLGFGIIGGKATGVIVKTILPGGVADQHGRLCSGD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 STISAHSNPVHWQHMETIELVNDGSGLGFGIIGGKATGVIVKTILPGGVADQHGRLCSGD
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB0 HILKIGDTDLAGMSSEQVAQVLRQCGNRVKLMIARGAIEERTAPTALGITLSSSPTSTPE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 HILKIGDTDLAGMSSEQVAQVLRQCGNRVKLMIARGAIEERTAPTALGITLSSSPTSTPE
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB0 LRVDASTQKGEESETFDVELTKNVQGLGITIAGYIGDKKLEPSGIFVKSITKSSAVEHDG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LRVDASTQKGEESETFDVELTKNVQGLGITIAGYIGDKKLEPSGIFVKSITKSSAVEHDG
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KB0 RIQIGDQIIAVDGTNLQGFTNQQAVEVLRHTGQTVLLTLMRRGMKQEAELMSREDVTKDA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 RIQIGDQIIAVDGTNLQGFTNQQAVEVLRHTGQTVLLTLMRRGMKQEAELMSREDVTKDA
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KB0 DLSPVNASIIKENYEKDEDFLSSTRNTNILPTEEEGYPLLSAEIEEIEDAQKQEAALLTK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 DLSPVNASIIKENYEKDEDFLSSTRNTNILPTEEEGYPLLSAEIEEIEDAQKQEAALLTK
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KB0 WQRIMGINYEIVVAHVSKFSENSGLGISLEATVGHHFIRSVLPEGPVGHSGKLFSGDELL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 WQRIMGINYEIVVAHVSKFSENSGLGISLEATVGHHFIRSVLPEGPVGHSGKLFSGDELL
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KB0 EVNGITLLGENHQDVVNILKELPIEVTMVCCRRTVPPTTQSELDSLDLCDIELTEKPHVD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 EVNGITLLGENHQDVVNILKELPIEVTMVCCRRTVPPTTQSELDSLDLCDIELTEKPHVD
              610       620       630       640       650       660

              670       680       690       700       710       720
pF1KB0 LGEFIGSSETEDPVLAMTDAGQSTEEVQAPLAMWEAGIQHIELEKGSKGLGFSILDYQDP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LGEFIGSSETEDPVLAMTDAGQSTEEVQAPLAMWEAGIQHIELEKGSKGLGFSILDYQDP
              670       680       690       700       710       720

              730       740       750       760       770       780
pF1KB0 IDPASTVIIIRSLVPGGIAEKDGRLLPGDRLMFVNDVNLENSSLEEAVEALKGAPSGTVR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 IDPASTVIIIRSLVPGGIAEKDGRLLPGDRLMFVNDVNLENSSLEEAVEALKGAPSGTVR
              730       740       750       760       770       780

              790       800       810       820       830       840
pF1KB0 IGVAKPLPLSPEEGYVSAKEDSFLYPPHSCEEAGLADKPLFRADLALVGTNDADLVDEST
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 IGVAKPLPLSPEEGYVSAKEDSFLYPPHSCEEAGLADKPLFRADLALVGTNDADLVDEST
              790       800       810       820       830       840

              850       860       870       880       890       900
pF1KB0 FESPYSPENDSIYSTQASILSLHGSSCGDGLNYGSSLPSSPPKDVIENSCDPVLDLHMSL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 FESPYSPENDSIYSTQASILSLHGSSCGDGLNYGSSLPSSPPKDVIENSCDPVLDLHMSL
              850       860       870       880       890       900

              910       920       930       940       950       960
pF1KB0 EELYTQNLLQRQDENTPSVDISMGPASGFTINDYTPANAIEQQYECENTIVWTESHLPSE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 EELYTQNLLQRQDENTPSVDISMGPASGFTINDYTPANAIEQQYECENTIVWTESHLPSE
              910       920       930       940       950       960

              970       980       990      1000      1010      1020
pF1KB0 VISSAELPSVLPDSAGKGSEYLLEQSSLACNAECVMLQNVSKESFERTINIAKGNSSLGM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 VISSAELPSVLPDSAGKGSEYLLEQSSLACNAECVMLQNVSKESFERTINIAKGNSSLGM
              970       980       990      1000      1010      1020

             1030      1040      1050      1060      1070      1080
pF1KB0 TVSANKDGLGMIVRSIIHGGAISRDGRIAIGDCILSINEESTISVTNAQARAMLRRHSLI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 TVSANKDGLGMIVRSIIHGGAISRDGRIAIGDCILSINEESTISVTNAQARAMLRRHSLI
             1030      1040      1050      1060      1070      1080

             1090      1100      1110      1120      1130      1140
pF1KB0 GPDIKITYVPAEHLEEFKISLGQQSGRVMALDIFSSYTGRDIPELPEREEGEGEESELQN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 GPDIKITYVPAEHLEEFKISLGQQSGRVMALDIFSSYTGRDIPELPEREEGEGEESELQN
             1090      1100      1110      1120      1130      1140

             1150      1160      1170      1180      1190      1200
pF1KB0 TAYSNWNQPRRVELWREPSKSLGISIVGGRGMGSRLSNGEVMRGIFIKHVLEDSPAGKNG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 TAYSNWNQPRRVELWREPSKSLGISIVGGRGMGSRLSNGEVMRGIFIKHVLEDSPAGKNG
             1150      1160      1170      1180      1190      1200

             1210      1220      1230      1240      1250      1260
pF1KB0 TLKPGDRIVEVDGMDLRDASHEQAVEAIRKAGNPVVFMVQSIINRPRKSPLPSLLHNLYP
       :::::::::::::::::::::::::::::::::::::::::::::::             
XP_006 TLKPGDRIVEVDGMDLRDASHEQAVEAIRKAGNPVVFMVQSIINRPR-------------
             1210      1220      1230      1240                    

             1270      1280      1290      1300      1310      1320
pF1KB0 KYNFSSTNPFADSLQINADKAPSQSESEPEKAPLCSVPPPPPSAFAEMGSDHTQSSASKI
                           ::::::::::::::::::::::::::::::::::::::::
XP_006 --------------------APSQSESEPEKAPLCSVPPPPPSAFAEMGSDHTQSSASKI
                          1250      1260      1270      1280       

             1330      1340      1350      1360      1370      1380
pF1KB0 SQDVDKEDEFGYSWKNIRERYGTLTGELHMIELEKGHSGLGLSLAGNKDRSRMSVFIVGI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 SQDVDKEDEFGYSWKNIRERYGTLTGELHMIELEKGHSGLGLSLAGNKDRSRMSVFIVGI
      1290      1300      1310      1320      1330      1340       

             1390      1400      1410      1420      1430      1440
pF1KB0 DPNGAAGKDGRLQIADELLEINGQILYGRSHQNASSIIKCAPSKVKIIFIRNKDAVNQMA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 DPNGAAGKDGRLQIADELLEINGQILYGRSHQNASSIIKCAPSKVKIIFIRNKDAVNQMA
      1350      1360      1370      1380      1390      1400       

             1450      1460      1470      1480      1490      1500
pF1KB0 VCPGNAVEPLPSNSENLQNKETEPTVTTSDAAVDLSSFKNVQHLELPKDQGGLGIAISEE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 VCPGNAVEPLPSNSENLQNKETEPTVTTSDAAVDLSSFKNVQHLELPKDQGGLGIAISEE
      1410      1420      1430      1440      1450      1460       

             1510      1520      1530      1540      1550      1560
pF1KB0 DTLSGVIIKSLTEHGVAATDGRLKVGDQILAVDDEIVVGYPIEKFISLLKTAKMTVKLTI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 DTLSGVIIKSLTEHGVAATDGRLKVGDQILAVDDEIVVGYPIEKFISLLKTAKMTVKLTI
      1470      1480      1490      1500      1510      1520       

             1570      1580      1590      1600      1610      1620
pF1KB0 HAENPDSQAVPSAAGAASGEKKNSSQSLMVPQSGSPEPESIRNTSRSSTPAIFASDPATC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 HAENPDSQAVPSAAGAASGEKKNSSQSLMVPQSGSPEPESIRNTSRSSTPAIFASDPATC
      1530      1540      1550      1560      1570      1580       

             1630      1640      1650      1660      1670      1680
pF1KB0 PIIPGCETTIEISKGRTGLGLSIVGGSDTLLGAIIIHEVYEEGAACKDGRLWAGDQILEV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 PIIPGCETTIEISKGRTGLGLSIVGGSDTLLGAIIIHEVYEEGAACKDGRLWAGDQILEV
      1590      1600      1610      1620      1630      1640       

             1690      1700      1710      1720      1730      1740
pF1KB0 NGIDLRKATHDEAINVLRQTPQRVRLTLYRDEAPYKEEEVCDTLTIELQKKPGKGLGLSI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 NGIDLRKATHDEAINVLRQTPQRVRLTLYRDEAPYKEEEVCDTLTIELQKKPGKGLGLSI
      1650      1660      1670      1680      1690      1700       

             1750      1760      1770      1780      1790          
pF1KB0 VGKRNDTGVFVSDIVKGGIADADGRLMQGDQILMVNGEDVRNATQEAVAALLK-------
       :::::::::::::::::::::::::::::::::::::::::::::::::::::       
XP_006 VGKRNDTGVFVSDIVKGGIADADGRLMQGDQILMVNGEDVRNATQEAVAALLKCSLGTVT
      1710      1720      1730      1740      1750      1760       

                                1800      1810      1820      1830 
pF1KB0 ----------------------VSEGSLSSFTFPLSGSSTSESLESSSKKNALASEIQGL
                             ::::::::::::::::::::::::::::::::::::::
XP_006 LEVGRIKAGPFHSERRPSQSSQVSEGSLSSFTFPLSGSSTSESLESSSKKNALASEIQGL
      1770      1780      1790      1800      1810      1820       

            1840      1850      1860      1870      1880      1890 
pF1KB0 RTVEMKKGPTDSLGISIAGGVGSPLGDVPIFIAMMHPTGVAAQTQKLRVGDRIVTICGTS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 RTVEMKKGPTDSLGISIAGGVGSPLGDVPIFIAMMHPTGVAAQTQKLRVGDRIVTICGTS
      1830      1840      1850      1860      1870      1880       

            1900      1910      1920      1930      1940      1950 
pF1KB0 TEGMTHTQAVNLLKNASGSIEMQVVAGGDVSVVTGHQQEPASSSLSFTGLTSSSIFQDDL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 TEGMTHTQAVNLLKNASGSIEMQVVAGGDVSVVTGHQQEPASSSLSFTGLTSSSIFQDDL
      1890      1900      1910      1920      1930      1940       

            1960      1970      1980      1990      2000      2010 
pF1KB0 GPPQCKSITLERGPDGLGFSIVGGYGSPHGDLPIYVKTVFAKGAASEDGRLKRGDQIIAV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 GPPQCKSITLERGPDGLGFSIVGGYGSPHGDLPIYVKTVFAKGAASEDGRLKRGDQIIAV
      1950      1960      1970      1980      1990      2000       

            2020      2030      2040 
pF1KB0 NGQSLEGVTHEEAVAILKRTKGTVTLMVLS
       ::::::::::::::::::::::::::::::
XP_006 NGQSLEGVTHEEAVAILKRTKGTVTLMVLS
      2010      2020      2030       




2041 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Wed Nov  2 22:37:02 2016 done: Wed Nov  2 22:37:06 2016
 Total Scan time: 21.150 Total Display time:  1.510

Function used was FASTA [36.3.4 Apr, 2011]
Inquiries or Suggestions ?
Send a message to flexiclone AT kazusagt.com