Result of FASTA (omim) for pF1KB0009
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB0009, 1654 aa
  1>>>pF1KB0009 1654 - 1654 aa - 1654 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 10.1917+/-0.000649; mu= -2.1374+/- 0.040
 mean_var=242.8392+/-48.924, 0's: 0 Z-trim(110.6): 367  B-trim: 22 in 1/54
 Lambda= 0.082303
 statistics sampled from 18646 (19044) to 18646 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.543), E-opt: 0.2 (0.223), width:  16
 Scan time: 17.990

The best scores are:                                      opt bits E(85289)
NP_001309918 (OMIM: 604605,608901) kalirin isoform (1654) 10922 1312.5       0
XP_011511583 (OMIM: 604605,608901) PREDICTED: kali (2977) 10767 1294.3       0
XP_016862922 (OMIM: 604605,608901) PREDICTED: kali (1656) 10752 1292.3       0
XP_006713874 (OMIM: 604605,608901) PREDICTED: kali (2979) 10597 1274.1       0
NP_001309919 (OMIM: 604605,608901) kalirin isoform (1650) 9434 1135.8       0
XP_016862923 (OMIM: 604605,608901) PREDICTED: kali (1652) 9264 1115.7       0
XP_006713875 (OMIM: 604605,608901) PREDICTED: kali (2975) 9109 1097.4       0
NP_001309921 (OMIM: 604605,608901) kalirin isoform (1613) 6223 754.6 1.6e-216
NP_003938 (OMIM: 604605,608901) kalirin isoform 2  (1663) 6223 754.6 1.7e-216
NP_001309917 (OMIM: 604605,608901) kalirin isoform (2396) 6223 754.7 2.3e-216
NP_001019831 (OMIM: 604605,608901) kalirin isoform (2986) 6223 754.7 2.7e-216
NP_001309920 (OMIM: 604605,608901) kalirin isoform (1641) 6133 743.9 2.7e-213
XP_016862924 (OMIM: 604605,608901) PREDICTED: kali (1643) 6133 743.9 2.7e-213
XP_006713878 (OMIM: 604605,608901) PREDICTED: kali (1665) 6053 734.4  2e-210
XP_016862921 (OMIM: 604605,608901) PREDICTED: kali (2366) 6053 734.5 2.7e-210
XP_011511587 (OMIM: 604605,608901) PREDICTED: kali (2367) 6053 734.5 2.7e-210
XP_016862920 (OMIM: 604605,608901) PREDICTED: kali (2398) 6053 734.5 2.7e-210
XP_011511585 (OMIM: 604605,608901) PREDICTED: kali (2401) 6053 734.5 2.7e-210
XP_016862919 (OMIM: 604605,608901) PREDICTED: kali (2955) 6053 734.5 3.2e-210
XP_006713877 (OMIM: 604605,608901) PREDICTED: kali (2956) 6053 734.5 3.2e-210
XP_016862918 (OMIM: 604605,608901) PREDICTED: kali (2968) 6053 734.5 3.2e-210
XP_011511582 (OMIM: 604605,608901) PREDICTED: kali (2987) 6053 734.5 3.2e-210
XP_011511581 (OMIM: 604605,608901) PREDICTED: kali (2987) 6053 734.5 3.2e-210
XP_006713873 (OMIM: 604605,608901) PREDICTED: kali (2988) 6053 734.5 3.2e-210
XP_006713876 (OMIM: 604605,608901) PREDICTED: kali (2966) 5978 725.6 1.5e-207
XP_016865292 (OMIM: 601893,617061) PREDICTED: trip (2612) 4993 608.6 2.2e-172
XP_016865291 (OMIM: 601893,617061) PREDICTED: trip (2880) 3786 465.3 3.4e-129
XP_016865290 (OMIM: 601893,617061) PREDICTED: trip (3093) 3786 465.4 3.6e-129
NP_009049 (OMIM: 601893,617061) triple functional  (3097) 3786 465.4 3.6e-129
XP_011512411 (OMIM: 601893,617061) PREDICTED: trip (3048) 3782 464.9 4.9e-129
XP_011512410 (OMIM: 601893,617061) PREDICTED: trip (3058) 3781 464.8 5.4e-129
XP_011512409 (OMIM: 601893,617061) PREDICTED: trip (3076) 3779 464.5 6.4e-129
XP_011512412 (OMIM: 601893,617061) PREDICTED: trip (3038) 3764 462.7 2.2e-128
NP_001309930 (OMIM: 604605,608901) kalirin isoform ( 667)  744 103.8 5.3e-21
NP_001309929 (OMIM: 604605,608901) kalirin isoform ( 668)  744 103.8 5.4e-21
NP_001309928 (OMIM: 604605,608901) kalirin isoform ( 668)  744 103.8 5.4e-21
NP_001309927 (OMIM: 604605,608901) kalirin isoform ( 669)  744 103.8 5.4e-21
NP_001309926 (OMIM: 604605,608901) kalirin isoform ( 699)  744 103.8 5.6e-21
NP_001309925 (OMIM: 604605,608901) kalirin isoform ( 700)  744 103.8 5.6e-21
NP_001309924 (OMIM: 604605,608901) kalirin isoform ( 701)  744 103.8 5.6e-21
NP_001309922 (OMIM: 604605,608901) kalirin isoform (1288)  744 103.9 9.3e-21
NP_008995 (OMIM: 604605,608901) kalirin isoform 3  (1289)  744 103.9 9.3e-21
NP_891992 (OMIM: 610215) rho guanine nucleotide ex ( 580)  617 88.7 1.6e-16
NP_001104740 (OMIM: 610215) rho guanine nucleotide ( 619)  617 88.7 1.7e-16
NP_001123203 (OMIM: 609526) puratrophin-1 isoform  (1110)  608 87.8   6e-16
XP_011521287 (OMIM: 609526) PREDICTED: puratrophin (1191)  608 87.8 6.3e-16
XP_011521290 (OMIM: 609526) PREDICTED: puratrophin (1191)  608 87.8 6.3e-16
XP_011521288 (OMIM: 609526) PREDICTED: puratrophin (1191)  608 87.8 6.3e-16
XP_011521289 (OMIM: 609526) PREDICTED: puratrophin (1191)  608 87.8 6.3e-16
NP_001123200 (OMIM: 609526) puratrophin-1 isoform  (1191)  608 87.8 6.3e-16


>>NP_001309918 (OMIM: 604605,608901) kalirin isoform 5 [  (1654 aa)
 initn: 10922 init1: 10922 opt: 10922  Z-score: 7023.4  bits: 1312.5 E(85289):    0
Smith-Waterman score: 10922; 100.0% identity (100.0% similar) in 1654 aa overlap (1-1654:1-1654)

               10        20        30        40        50        60
pF1KB0 MTDRFWDQWYLWYLRLLRLLDRGSFRNDGLKASDVLPILKEKVAFVSGGRDKRGGPILTF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MTDRFWDQWYLWYLRLLRLLDRGSFRNDGLKASDVLPILKEKVAFVSGGRDKRGGPILTF
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB0 PARSNHDRIRQEDLRKLVTYLASVPSEDVCKRGFTVIIDMRGSKWDLIKPLLKTLQEAFP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PARSNHDRIRQEDLRKLVTYLASVPSEDVCKRGFTVIIDMRGSKWDLIKPLLKTLQEAFP
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB0 AEIHVALIIKPDNFWQKQKTNFGSSKFIFETSMVSVEGLTKLVDPSQLTEEFDGSLDYNH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AEIHVALIIKPDNFWQKQKTNFGSSKFIFETSMVSVEGLTKLVDPSQLTEEFDGSLDYNH
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB0 EEWIELRLSLEEFFNSAVHLLSRLEDLQEMLARKEFPVDVEGSRRLIDEHTQLKKKVLKA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EEWIELRLSLEEFFNSAVHLLSRLEDLQEMLARKEFPVDVEGSRRLIDEHTQLKKKVLKA
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB0 PVEELDREGQRLLQCIRCSDGFSGRNCIPGSADFQSLVPKITSLLDKLHSTRQHLHQMWH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PVEELDREGQRLLQCIRCSDGFSGRNCIPGSADFQSLVPKITSLLDKLHSTRQHLHQMWH
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB0 VRKLKLDQCFQLRLFEQDAEKMFDWISHNKELFLQSHTEIGVSYQYALDLQTQHNHFAMN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VRKLKLDQCFQLRLFEQDAEKMFDWISHNKELFLQSHTEIGVSYQYALDLQTQHNHFAMN
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB0 SMNAYVNINRIMSVASRLSEAGHYASQQIKQISTQLDQEWKSFAAALDERSTILAMSAVF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SMNAYVNINRIMSVASRLSEAGHYASQQIKQISTQLDQEWKSFAAALDERSTILAMSAVF
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KB0 HQKAEQFLSGVDAWCKMCSEGGLPSEMQDLELAIHHHQTLYEQVTQAYTEVSQDGKALLD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HQKAEQFLSGVDAWCKMCSEGGLPSEMQDLELAIHHHQTLYEQVTQAYTEVSQDGKALLD
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KB0 VLQRPLSPGNSESLTATANYSKAVHQVLDVVHEVLHHQRRLESIWQHRKVRLHQRLQLCV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VLQRPLSPGNSESLTATANYSKAVHQVLDVVHEVLHHQRRLESIWQHRKVRLHQRLQLCV
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KB0 FQQDVQQVLDWIENHGEAFLSKHTGVGKSLHRARALQKRHDDFEEVAQNTYTNADKLLEA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FQQDVQQVLDWIENHGEAFLSKHTGVGKSLHRARALQKRHDDFEEVAQNTYTNADKLLEA
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KB0 AEQLAQTGECDPEEIYKAARHLEVRIQDFVRRVEQRKLLLDMSVSFHTHTKELWTWMEDL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AEQLAQTGECDPEEIYKAARHLEVRIQDFVRRVEQRKLLLDMSVSFHTHTKELWTWMEDL
              610       620       630       640       650       660

              670       680       690       700       710       720
pF1KB0 QKEMLEDVCADSVDAVQELIKQFQQQQTATLDATLNVIKEGEDLIQQLRSAPPSLGEPSE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QKEMLEDVCADSVDAVQELIKQFQQQQTATLDATLNVIKEGEDLIQQLRSAPPSLGEPSE
              670       680       690       700       710       720

              730       740       750       760       770       780
pF1KB0 ARDSAVSNNKTPHSSSISHIESVLQQLDDAQVQMEELFHERKIKLDIFLQLRIFEQYTIE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ARDSAVSNNKTPHSSSISHIESVLQQLDDAQVQMEELFHERKIKLDIFLQLRIFEQYTIE
              730       740       750       760       770       780

              790       800       810       820       830       840
pF1KB0 VTAELDAWNEDLLRQMNDFNTEDLTLAEQRLQRHTERKLAMNNMTFEVIQQGQDLHQYIT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VTAELDAWNEDLLRQMNDFNTEDLTLAEQRLQRHTERKLAMNNMTFEVIQQGQDLHQYIT
              790       800       810       820       830       840

              850       860       870       880       890       900
pF1KB0 EVQASGIELICEKDIDLAAQVQELLEFLHEKQHELELNAEQTHKRLEQCLQLRHLQAEVK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EVQASGIELICEKDIDLAAQVQELLEFLHEKQHELELNAEQTHKRLEQCLQLRHLQAEVK
              850       860       870       880       890       900

              910       920       930       940       950       960
pF1KB0 QVLGWIRNGESMLNASLVNASSLSEAEQLQREHEQFQLAIEKTHQSALQVQQKAEVLLQA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QVLGWIRNGESMLNASLVNASSLSEAEQLQREHEQFQLAIEKTHQSALQVQQKAEVLLQA
              910       920       930       940       950       960

              970       980       990      1000      1010      1020
pF1KB0 GHYDADAIRECAEKVALHWQQLMLKMEDRLKLVNASVAFYKTSEQVCSVLESLEQEYRRD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GHYDADAIRECAEKVALHWQQLMLKMEDRLKLVNASVAFYKTSEQVCSVLESLEQEYRRD
              970       980       990      1000      1010      1020

             1030      1040      1050      1060      1070      1080
pF1KB0 EDWCGGRDKLGPAAEIDHVIPLISKHLEQKEAFLKACTLARRNAEVFLKYIHRNNVSMPS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EDWCGGRDKLGPAAEIDHVIPLISKHLEQKEAFLKACTLARRNAEVFLKYIHRNNVSMPS
             1030      1040      1050      1060      1070      1080

             1090      1100      1110      1120      1130      1140
pF1KB0 VASHTRGPEQQVKAILSELLQRENRVLHFWTLKKRRLDQCQQYVVFERSAKQALDWIQET
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VASHTRGPEQQVKAILSELLQRENRVLHFWTLKKRRLDQCQQYVVFERSAKQALDWIQET
             1090      1100      1110      1120      1130      1140

             1150      1160      1170      1180      1190      1200
pF1KB0 GEFYLSTHTSTGETTEETQELLKEYGEFRVPAKQTKEKVKLLIQLADSFVEKGHIHATEI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GEFYLSTHTSTGETTEETQELLKEYGEFRVPAKQTKEKVKLLIQLADSFVEKGHIHATEI
             1150      1160      1170      1180      1190      1200

             1210      1220      1230      1240      1250      1260
pF1KB0 RKWVTTVDKHYRDFSLRMGKYRYSLEKALGVNTEDNKDLELDIIPASLSDREVKLRDANH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RKWVTTVDKHYRDFSLRMGKYRYSLEKALGVNTEDNKDLELDIIPASLSDREVKLRDANH
             1210      1220      1230      1240      1250      1260

             1270      1280      1290      1300      1310      1320
pF1KB0 EVNEEKRKSARKKEFIMAELLQTEKAYVRDLHECLETYLWEMTSGVEEIPPGILNKEHII
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EVNEEKRKSARKKEFIMAELLQTEKAYVRDLHECLETYLWEMTSGVEEIPPGILNKEHII
             1270      1280      1290      1300      1310      1320

             1330      1340      1350      1360      1370      1380
pF1KB0 FGNIQEIYDFHNNIFLKELEKYEQLPEDVGHCFVTWADKFQMYVTYCKNKPDSNQLILEH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FGNIQEIYDFHNNIFLKELEKYEQLPEDVGHCFVTWADKFQMYVTYCKNKPDSNQLILEH
             1330      1340      1350      1360      1370      1380

             1390      1400      1410      1420      1430      1440
pF1KB0 AGTFFDEIQQRHGLANSISSYLIKPVQRITKYQLLLKELLTCCEEGKGELKDGLEVMLSV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AGTFFDEIQQRHGLANSISSYLIKPVQRITKYQLLLKELLTCCEEGKGELKDGLEVMLSV
             1390      1400      1410      1420      1430      1440

             1450      1460      1470      1480      1490      1500
pF1KB0 PKKANDAMHVSMLEGFDENLDVQGELILQDAFQVWDPKSLIRKGRERHLFLFEISLVFSK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PKKANDAMHVSMLEGFDENLDVQGELILQDAFQVWDPKSLIRKGRERHLFLFEISLVFSK
             1450      1460      1470      1480      1490      1500

             1510      1520      1530      1540      1550      1560
pF1KB0 EIKDSSGHTKYVYKNKLLTSELGVTEHVEGDPCKFALWSGRTPSSDNKTVLKASNIETKQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EIKDSSGHTKYVYKNKLLTSELGVTEHVEGDPCKFALWSGRTPSSDNKTVLKASNIETKQ
             1510      1520      1530      1540      1550      1560

             1570      1580      1590      1600      1610      1620
pF1KB0 EWIKNIREVIQERIIHLKGALKEPLQLPKTPAKQRNNSKRDGVEDIDSQGDGSSQPDTIS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EWIKNIREVIQERIIHLKGALKEPLQLPKTPAKQRNNSKRDGVEDIDSQGDGSSQPDTIS
             1570      1580      1590      1600      1610      1620

             1630      1640      1650    
pF1KB0 IASRTSQNTVDSDKDGNLVPRWHLGPGDPFSTYV
       ::::::::::::::::::::::::::::::::::
NP_001 IASRTSQNTVDSDKDGNLVPRWHLGPGDPFSTYV
             1630      1640      1650    

>>XP_011511583 (OMIM: 604605,608901) PREDICTED: kalirin   (2977 aa)
 initn: 10767 init1: 10767 opt: 10767  Z-score: 6920.1  bits: 1294.3 E(85289):    0
Smith-Waterman score: 10767; 100.0% identity (100.0% similar) in 1634 aa overlap (1-1634:1-1634)

               10        20        30        40        50        60
pF1KB0 MTDRFWDQWYLWYLRLLRLLDRGSFRNDGLKASDVLPILKEKVAFVSGGRDKRGGPILTF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MTDRFWDQWYLWYLRLLRLLDRGSFRNDGLKASDVLPILKEKVAFVSGGRDKRGGPILTF
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB0 PARSNHDRIRQEDLRKLVTYLASVPSEDVCKRGFTVIIDMRGSKWDLIKPLLKTLQEAFP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PARSNHDRIRQEDLRKLVTYLASVPSEDVCKRGFTVIIDMRGSKWDLIKPLLKTLQEAFP
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB0 AEIHVALIIKPDNFWQKQKTNFGSSKFIFETSMVSVEGLTKLVDPSQLTEEFDGSLDYNH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AEIHVALIIKPDNFWQKQKTNFGSSKFIFETSMVSVEGLTKLVDPSQLTEEFDGSLDYNH
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB0 EEWIELRLSLEEFFNSAVHLLSRLEDLQEMLARKEFPVDVEGSRRLIDEHTQLKKKVLKA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EEWIELRLSLEEFFNSAVHLLSRLEDLQEMLARKEFPVDVEGSRRLIDEHTQLKKKVLKA
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB0 PVEELDREGQRLLQCIRCSDGFSGRNCIPGSADFQSLVPKITSLLDKLHSTRQHLHQMWH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PVEELDREGQRLLQCIRCSDGFSGRNCIPGSADFQSLVPKITSLLDKLHSTRQHLHQMWH
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB0 VRKLKLDQCFQLRLFEQDAEKMFDWISHNKELFLQSHTEIGVSYQYALDLQTQHNHFAMN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VRKLKLDQCFQLRLFEQDAEKMFDWISHNKELFLQSHTEIGVSYQYALDLQTQHNHFAMN
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB0 SMNAYVNINRIMSVASRLSEAGHYASQQIKQISTQLDQEWKSFAAALDERSTILAMSAVF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SMNAYVNINRIMSVASRLSEAGHYASQQIKQISTQLDQEWKSFAAALDERSTILAMSAVF
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KB0 HQKAEQFLSGVDAWCKMCSEGGLPSEMQDLELAIHHHQTLYEQVTQAYTEVSQDGKALLD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HQKAEQFLSGVDAWCKMCSEGGLPSEMQDLELAIHHHQTLYEQVTQAYTEVSQDGKALLD
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KB0 VLQRPLSPGNSESLTATANYSKAVHQVLDVVHEVLHHQRRLESIWQHRKVRLHQRLQLCV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VLQRPLSPGNSESLTATANYSKAVHQVLDVVHEVLHHQRRLESIWQHRKVRLHQRLQLCV
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KB0 FQQDVQQVLDWIENHGEAFLSKHTGVGKSLHRARALQKRHDDFEEVAQNTYTNADKLLEA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FQQDVQQVLDWIENHGEAFLSKHTGVGKSLHRARALQKRHDDFEEVAQNTYTNADKLLEA
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KB0 AEQLAQTGECDPEEIYKAARHLEVRIQDFVRRVEQRKLLLDMSVSFHTHTKELWTWMEDL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AEQLAQTGECDPEEIYKAARHLEVRIQDFVRRVEQRKLLLDMSVSFHTHTKELWTWMEDL
              610       620       630       640       650       660

              670       680       690       700       710       720
pF1KB0 QKEMLEDVCADSVDAVQELIKQFQQQQTATLDATLNVIKEGEDLIQQLRSAPPSLGEPSE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QKEMLEDVCADSVDAVQELIKQFQQQQTATLDATLNVIKEGEDLIQQLRSAPPSLGEPSE
              670       680       690       700       710       720

              730       740       750       760       770       780
pF1KB0 ARDSAVSNNKTPHSSSISHIESVLQQLDDAQVQMEELFHERKIKLDIFLQLRIFEQYTIE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ARDSAVSNNKTPHSSSISHIESVLQQLDDAQVQMEELFHERKIKLDIFLQLRIFEQYTIE
              730       740       750       760       770       780

              790       800       810       820       830       840
pF1KB0 VTAELDAWNEDLLRQMNDFNTEDLTLAEQRLQRHTERKLAMNNMTFEVIQQGQDLHQYIT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VTAELDAWNEDLLRQMNDFNTEDLTLAEQRLQRHTERKLAMNNMTFEVIQQGQDLHQYIT
              790       800       810       820       830       840

              850       860       870       880       890       900
pF1KB0 EVQASGIELICEKDIDLAAQVQELLEFLHEKQHELELNAEQTHKRLEQCLQLRHLQAEVK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EVQASGIELICEKDIDLAAQVQELLEFLHEKQHELELNAEQTHKRLEQCLQLRHLQAEVK
              850       860       870       880       890       900

              910       920       930       940       950       960
pF1KB0 QVLGWIRNGESMLNASLVNASSLSEAEQLQREHEQFQLAIEKTHQSALQVQQKAEVLLQA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QVLGWIRNGESMLNASLVNASSLSEAEQLQREHEQFQLAIEKTHQSALQVQQKAEVLLQA
              910       920       930       940       950       960

              970       980       990      1000      1010      1020
pF1KB0 GHYDADAIRECAEKVALHWQQLMLKMEDRLKLVNASVAFYKTSEQVCSVLESLEQEYRRD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GHYDADAIRECAEKVALHWQQLMLKMEDRLKLVNASVAFYKTSEQVCSVLESLEQEYRRD
              970       980       990      1000      1010      1020

             1030      1040      1050      1060      1070      1080
pF1KB0 EDWCGGRDKLGPAAEIDHVIPLISKHLEQKEAFLKACTLARRNAEVFLKYIHRNNVSMPS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EDWCGGRDKLGPAAEIDHVIPLISKHLEQKEAFLKACTLARRNAEVFLKYIHRNNVSMPS
             1030      1040      1050      1060      1070      1080

             1090      1100      1110      1120      1130      1140
pF1KB0 VASHTRGPEQQVKAILSELLQRENRVLHFWTLKKRRLDQCQQYVVFERSAKQALDWIQET
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VASHTRGPEQQVKAILSELLQRENRVLHFWTLKKRRLDQCQQYVVFERSAKQALDWIQET
             1090      1100      1110      1120      1130      1140

             1150      1160      1170      1180      1190      1200
pF1KB0 GEFYLSTHTSTGETTEETQELLKEYGEFRVPAKQTKEKVKLLIQLADSFVEKGHIHATEI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GEFYLSTHTSTGETTEETQELLKEYGEFRVPAKQTKEKVKLLIQLADSFVEKGHIHATEI
             1150      1160      1170      1180      1190      1200

             1210      1220      1230      1240      1250      1260
pF1KB0 RKWVTTVDKHYRDFSLRMGKYRYSLEKALGVNTEDNKDLELDIIPASLSDREVKLRDANH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RKWVTTVDKHYRDFSLRMGKYRYSLEKALGVNTEDNKDLELDIIPASLSDREVKLRDANH
             1210      1220      1230      1240      1250      1260

             1270      1280      1290      1300      1310      1320
pF1KB0 EVNEEKRKSARKKEFIMAELLQTEKAYVRDLHECLETYLWEMTSGVEEIPPGILNKEHII
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EVNEEKRKSARKKEFIMAELLQTEKAYVRDLHECLETYLWEMTSGVEEIPPGILNKEHII
             1270      1280      1290      1300      1310      1320

             1330      1340      1350      1360      1370      1380
pF1KB0 FGNIQEIYDFHNNIFLKELEKYEQLPEDVGHCFVTWADKFQMYVTYCKNKPDSNQLILEH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FGNIQEIYDFHNNIFLKELEKYEQLPEDVGHCFVTWADKFQMYVTYCKNKPDSNQLILEH
             1330      1340      1350      1360      1370      1380

             1390      1400      1410      1420      1430      1440
pF1KB0 AGTFFDEIQQRHGLANSISSYLIKPVQRITKYQLLLKELLTCCEEGKGELKDGLEVMLSV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AGTFFDEIQQRHGLANSISSYLIKPVQRITKYQLLLKELLTCCEEGKGELKDGLEVMLSV
             1390      1400      1410      1420      1430      1440

             1450      1460      1470      1480      1490      1500
pF1KB0 PKKANDAMHVSMLEGFDENLDVQGELILQDAFQVWDPKSLIRKGRERHLFLFEISLVFSK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PKKANDAMHVSMLEGFDENLDVQGELILQDAFQVWDPKSLIRKGRERHLFLFEISLVFSK
             1450      1460      1470      1480      1490      1500

             1510      1520      1530      1540      1550      1560
pF1KB0 EIKDSSGHTKYVYKNKLLTSELGVTEHVEGDPCKFALWSGRTPSSDNKTVLKASNIETKQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EIKDSSGHTKYVYKNKLLTSELGVTEHVEGDPCKFALWSGRTPSSDNKTVLKASNIETKQ
             1510      1520      1530      1540      1550      1560

             1570      1580      1590      1600      1610      1620
pF1KB0 EWIKNIREVIQERIIHLKGALKEPLQLPKTPAKQRNNSKRDGVEDIDSQGDGSSQPDTIS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EWIKNIREVIQERIIHLKGALKEPLQLPKTPAKQRNNSKRDGVEDIDSQGDGSSQPDTIS
             1570      1580      1590      1600      1610      1620

             1630      1640      1650                              
pF1KB0 IASRTSQNTVDSDKDGNLVPRWHLGPGDPFSTYV                          
       ::::::::::::::                                              
XP_011 IASRTSQNTVDSDKLSGGCELTVVLQDFSAGHSSELTIQVGQTVELLERPSERPGWCLVR
             1630      1640      1650      1660      1670      1680

>--
 initn: 624 init1: 215 opt: 744  Z-score: 488.2  bits: 104.1 E(85289): 1.9e-20
Smith-Waterman score: 744; 34.6% identity (66.2% similar) in 399 aa overlap (1264-1650:1912-2300)

          1240      1250      1260      1270      1280      1290   
pF1KB0 EDNKDLELDIIPASLSDREVKLRDANHEVNEEKRKSARKKEFIMAELLQTEKAYVRDLHE
                                     :.: :. : . :.. ::.:::: ::.::  
XP_011 GSSYRGSLKDPAGCLNEGMAPPTPPKNPEEEQKAKALRGRMFVLNELVQTEKDYVKDLGI
            1890      1900      1910      1920      1930      1940 

          1300        1310      1320      1330      1340      1350 
pF1KB0 CLETYLWEMTSGVEE--IPPGILNKEHIIFGNIQEIYDFHNNIFLKELEKYEQLPEDVGH
        .: .. .    .::  .:  . .:..:.::::..:::.:...:: ::::  :  . ...
XP_011 VVEGFMKR----IEEKGVPEDMRGKDKIVFGNIHQIYDWHKDFFLAELEKCIQEQDRLAQ
                1950      1960      1970      1980      1990       

            1360      1370      1380      1390      1400      1410 
pF1KB0 CFVTWADKFQMYVTYCKNKPDSNQLILEHAGTFFDEIQQRHGLANSISSYLIKPVQRITK
        :.    :...:: ::.::: :. .. :.  ..:.:..:. .   ..:..::::.:::::
XP_011 LFIKHERKLHIYVWYCQNKPRSEYIVAEY-DAYFEEVKQEINQRLTLSDFLIKPIQRITK
      2000      2010      2020       2030      2040      2050      

            1420      1430         1440      1450      1460        
pF1KB0 YQLLLKELLTCCEEGKGELKD---GLEVMLSVPKKANDAMHVSMLEGFDENLDVQGELIL
       ::::::..:   :..  : .:   ..:.:  :::. :: :... :.::. .: .::.:. 
XP_011 YQLLLKDFLRYSEKAGLECSDIEKAVELMCLVPKRCNDMMNLGRLQGFEGTLTAQGKLLQ
       2060      2070      2080      2090      2100      2110      

     1470       1480      1490      1500      1510      1520       
pF1KB0 QDAFQVWD-PKSLIRKGRERHLFLFEISLVFSKEIKDSSGHTKYVYKNKLLTSELGVTEH
       ::.: : .   ..  . .::..::::  ..::. .. .:    :..: ..  . : . :.
XP_011 QDTFYVIELDAGMQSRTKERRVFLFEQIVIFSELLRKGSLTPGYMFKRSIKMNYLVLEEN
       2120      2130      2140      2150      2160      2170      

      1530      1540      1550      1560      1570      1580       
pF1KB0 VEGDPCKFALWSGRTPSSDNKTVLKASNIETKQEWIKNIREVIQERIIHLKGALKEPLQL
       :..::::::: . .:   ....::.:.: . .: :...: .:.. .   :. ::. :.. 
XP_011 VDNDPCKFALMNRET---SERVVLQAANADIQQAWVQDINQVLETQRDFLN-ALQSPIEY
       2180      2190         2200      2210      2220       2230  

         1590      1600         1610      1620      1630      1640 
pF1KB0 PK---TPAKQRNNSKR---DGVEDIDSQGDGSSQPDTISIASRTSQNTVDSDKDGNLVPR
        .   . : .:..  :    . .  .:   :: .:   :  .        : ..:.   .
XP_011 QRKERSTAVMRSQPARLPQASPRPYSSVPAGSEKPPKGSSYNPPLPPLKISTSNGSPGFE
           2240      2250      2260      2270      2280      2290  

            1650                                                   
pF1KB0 WHLGPGDPFSTYV                                               
       .:  ::: :                                                   
XP_011 YHQ-PGDKFEASKQNDLGGCNGTSSMAVIKDYYALKENEICVSQGEVVQVLAVNQQNMCL
            2300      2310      2320      2330      2340      2350 

>>XP_016862922 (OMIM: 604605,608901) PREDICTED: kalirin   (1656 aa)
 initn: 10752 init1: 10752 opt: 10752  Z-score: 6914.3  bits: 1292.3 E(85289):    0
Smith-Waterman score: 10752; 100.0% identity (100.0% similar) in 1632 aa overlap (23-1654:25-1656)

                 10        20        30        40        50        
pF1KB0   MTDRFWDQWYLWYLRLLRLLDRGSFRNDGLKASDVLPILKEKVAFVSGGRDKRGGPIL
                               ::::::::::::::::::::::::::::::::::::
XP_016 MNPPEGAAEEGGAADSDVDAFFRTGSFRNDGLKASDVLPILKEKVAFVSGGRDKRGGPIL
               10        20        30        40        50        60

       60        70        80        90       100       110        
pF1KB0 TFPARSNHDRIRQEDLRKLVTYLASVPSEDVCKRGFTVIIDMRGSKWDLIKPLLKTLQEA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TFPARSNHDRIRQEDLRKLVTYLASVPSEDVCKRGFTVIIDMRGSKWDLIKPLLKTLQEA
               70        80        90       100       110       120

      120       130       140       150       160       170        
pF1KB0 FPAEIHVALIIKPDNFWQKQKTNFGSSKFIFETSMVSVEGLTKLVDPSQLTEEFDGSLDY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FPAEIHVALIIKPDNFWQKQKTNFGSSKFIFETSMVSVEGLTKLVDPSQLTEEFDGSLDY
              130       140       150       160       170       180

      180       190       200       210       220       230        
pF1KB0 NHEEWIELRLSLEEFFNSAVHLLSRLEDLQEMLARKEFPVDVEGSRRLIDEHTQLKKKVL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NHEEWIELRLSLEEFFNSAVHLLSRLEDLQEMLARKEFPVDVEGSRRLIDEHTQLKKKVL
              190       200       210       220       230       240

      240       250       260       270       280       290        
pF1KB0 KAPVEELDREGQRLLQCIRCSDGFSGRNCIPGSADFQSLVPKITSLLDKLHSTRQHLHQM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KAPVEELDREGQRLLQCIRCSDGFSGRNCIPGSADFQSLVPKITSLLDKLHSTRQHLHQM
              250       260       270       280       290       300

      300       310       320       330       340       350        
pF1KB0 WHVRKLKLDQCFQLRLFEQDAEKMFDWISHNKELFLQSHTEIGVSYQYALDLQTQHNHFA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 WHVRKLKLDQCFQLRLFEQDAEKMFDWISHNKELFLQSHTEIGVSYQYALDLQTQHNHFA
              310       320       330       340       350       360

      360       370       380       390       400       410        
pF1KB0 MNSMNAYVNINRIMSVASRLSEAGHYASQQIKQISTQLDQEWKSFAAALDERSTILAMSA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MNSMNAYVNINRIMSVASRLSEAGHYASQQIKQISTQLDQEWKSFAAALDERSTILAMSA
              370       380       390       400       410       420

      420       430       440       450       460       470        
pF1KB0 VFHQKAEQFLSGVDAWCKMCSEGGLPSEMQDLELAIHHHQTLYEQVTQAYTEVSQDGKAL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VFHQKAEQFLSGVDAWCKMCSEGGLPSEMQDLELAIHHHQTLYEQVTQAYTEVSQDGKAL
              430       440       450       460       470       480

      480       490       500       510       520       530        
pF1KB0 LDVLQRPLSPGNSESLTATANYSKAVHQVLDVVHEVLHHQRRLESIWQHRKVRLHQRLQL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LDVLQRPLSPGNSESLTATANYSKAVHQVLDVVHEVLHHQRRLESIWQHRKVRLHQRLQL
              490       500       510       520       530       540

      540       550       560       570       580       590        
pF1KB0 CVFQQDVQQVLDWIENHGEAFLSKHTGVGKSLHRARALQKRHDDFEEVAQNTYTNADKLL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CVFQQDVQQVLDWIENHGEAFLSKHTGVGKSLHRARALQKRHDDFEEVAQNTYTNADKLL
              550       560       570       580       590       600

      600       610       620       630       640       650        
pF1KB0 EAAEQLAQTGECDPEEIYKAARHLEVRIQDFVRRVEQRKLLLDMSVSFHTHTKELWTWME
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EAAEQLAQTGECDPEEIYKAARHLEVRIQDFVRRVEQRKLLLDMSVSFHTHTKELWTWME
              610       620       630       640       650       660

      660       670       680       690       700       710        
pF1KB0 DLQKEMLEDVCADSVDAVQELIKQFQQQQTATLDATLNVIKEGEDLIQQLRSAPPSLGEP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DLQKEMLEDVCADSVDAVQELIKQFQQQQTATLDATLNVIKEGEDLIQQLRSAPPSLGEP
              670       680       690       700       710       720

      720       730       740       750       760       770        
pF1KB0 SEARDSAVSNNKTPHSSSISHIESVLQQLDDAQVQMEELFHERKIKLDIFLQLRIFEQYT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SEARDSAVSNNKTPHSSSISHIESVLQQLDDAQVQMEELFHERKIKLDIFLQLRIFEQYT
              730       740       750       760       770       780

      780       790       800       810       820       830        
pF1KB0 IEVTAELDAWNEDLLRQMNDFNTEDLTLAEQRLQRHTERKLAMNNMTFEVIQQGQDLHQY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IEVTAELDAWNEDLLRQMNDFNTEDLTLAEQRLQRHTERKLAMNNMTFEVIQQGQDLHQY
              790       800       810       820       830       840

      840       850       860       870       880       890        
pF1KB0 ITEVQASGIELICEKDIDLAAQVQELLEFLHEKQHELELNAEQTHKRLEQCLQLRHLQAE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ITEVQASGIELICEKDIDLAAQVQELLEFLHEKQHELELNAEQTHKRLEQCLQLRHLQAE
              850       860       870       880       890       900

      900       910       920       930       940       950        
pF1KB0 VKQVLGWIRNGESMLNASLVNASSLSEAEQLQREHEQFQLAIEKTHQSALQVQQKAEVLL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VKQVLGWIRNGESMLNASLVNASSLSEAEQLQREHEQFQLAIEKTHQSALQVQQKAEVLL
              910       920       930       940       950       960

      960       970       980       990      1000      1010        
pF1KB0 QAGHYDADAIRECAEKVALHWQQLMLKMEDRLKLVNASVAFYKTSEQVCSVLESLEQEYR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QAGHYDADAIRECAEKVALHWQQLMLKMEDRLKLVNASVAFYKTSEQVCSVLESLEQEYR
              970       980       990      1000      1010      1020

     1020      1030      1040      1050      1060      1070        
pF1KB0 RDEDWCGGRDKLGPAAEIDHVIPLISKHLEQKEAFLKACTLARRNAEVFLKYIHRNNVSM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RDEDWCGGRDKLGPAAEIDHVIPLISKHLEQKEAFLKACTLARRNAEVFLKYIHRNNVSM
             1030      1040      1050      1060      1070      1080

     1080      1090      1100      1110      1120      1130        
pF1KB0 PSVASHTRGPEQQVKAILSELLQRENRVLHFWTLKKRRLDQCQQYVVFERSAKQALDWIQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PSVASHTRGPEQQVKAILSELLQRENRVLHFWTLKKRRLDQCQQYVVFERSAKQALDWIQ
             1090      1100      1110      1120      1130      1140

     1140      1150      1160      1170      1180      1190        
pF1KB0 ETGEFYLSTHTSTGETTEETQELLKEYGEFRVPAKQTKEKVKLLIQLADSFVEKGHIHAT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ETGEFYLSTHTSTGETTEETQELLKEYGEFRVPAKQTKEKVKLLIQLADSFVEKGHIHAT
             1150      1160      1170      1180      1190      1200

     1200      1210      1220      1230      1240      1250        
pF1KB0 EIRKWVTTVDKHYRDFSLRMGKYRYSLEKALGVNTEDNKDLELDIIPASLSDREVKLRDA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EIRKWVTTVDKHYRDFSLRMGKYRYSLEKALGVNTEDNKDLELDIIPASLSDREVKLRDA
             1210      1220      1230      1240      1250      1260

     1260      1270      1280      1290      1300      1310        
pF1KB0 NHEVNEEKRKSARKKEFIMAELLQTEKAYVRDLHECLETYLWEMTSGVEEIPPGILNKEH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NHEVNEEKRKSARKKEFIMAELLQTEKAYVRDLHECLETYLWEMTSGVEEIPPGILNKEH
             1270      1280      1290      1300      1310      1320

     1320      1330      1340      1350      1360      1370        
pF1KB0 IIFGNIQEIYDFHNNIFLKELEKYEQLPEDVGHCFVTWADKFQMYVTYCKNKPDSNQLIL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IIFGNIQEIYDFHNNIFLKELEKYEQLPEDVGHCFVTWADKFQMYVTYCKNKPDSNQLIL
             1330      1340      1350      1360      1370      1380

     1380      1390      1400      1410      1420      1430        
pF1KB0 EHAGTFFDEIQQRHGLANSISSYLIKPVQRITKYQLLLKELLTCCEEGKGELKDGLEVML
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EHAGTFFDEIQQRHGLANSISSYLIKPVQRITKYQLLLKELLTCCEEGKGELKDGLEVML
             1390      1400      1410      1420      1430      1440

     1440      1450      1460      1470      1480      1490        
pF1KB0 SVPKKANDAMHVSMLEGFDENLDVQGELILQDAFQVWDPKSLIRKGRERHLFLFEISLVF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SVPKKANDAMHVSMLEGFDENLDVQGELILQDAFQVWDPKSLIRKGRERHLFLFEISLVF
             1450      1460      1470      1480      1490      1500

     1500      1510      1520      1530      1540      1550        
pF1KB0 SKEIKDSSGHTKYVYKNKLLTSELGVTEHVEGDPCKFALWSGRTPSSDNKTVLKASNIET
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SKEIKDSSGHTKYVYKNKLLTSELGVTEHVEGDPCKFALWSGRTPSSDNKTVLKASNIET
             1510      1520      1530      1540      1550      1560

     1560      1570      1580      1590      1600      1610        
pF1KB0 KQEWIKNIREVIQERIIHLKGALKEPLQLPKTPAKQRNNSKRDGVEDIDSQGDGSSQPDT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KQEWIKNIREVIQERIIHLKGALKEPLQLPKTPAKQRNNSKRDGVEDIDSQGDGSSQPDT
             1570      1580      1590      1600      1610      1620

     1620      1630      1640      1650    
pF1KB0 ISIASRTSQNTVDSDKDGNLVPRWHLGPGDPFSTYV
       ::::::::::::::::::::::::::::::::::::
XP_016 ISIASRTSQNTVDSDKDGNLVPRWHLGPGDPFSTYV
             1630      1640      1650      

>>XP_006713874 (OMIM: 604605,608901) PREDICTED: kalirin   (2979 aa)
 initn: 10597 init1: 10597 opt: 10597  Z-score: 6811.0  bits: 1274.1 E(85289):    0
Smith-Waterman score: 10597; 100.0% identity (100.0% similar) in 1612 aa overlap (23-1634:25-1636)

                 10        20        30        40        50        
pF1KB0   MTDRFWDQWYLWYLRLLRLLDRGSFRNDGLKASDVLPILKEKVAFVSGGRDKRGGPIL
                               ::::::::::::::::::::::::::::::::::::
XP_006 MNPPEGAAEEGGAADSDVDAFFRTGSFRNDGLKASDVLPILKEKVAFVSGGRDKRGGPIL
               10        20        30        40        50        60

       60        70        80        90       100       110        
pF1KB0 TFPARSNHDRIRQEDLRKLVTYLASVPSEDVCKRGFTVIIDMRGSKWDLIKPLLKTLQEA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 TFPARSNHDRIRQEDLRKLVTYLASVPSEDVCKRGFTVIIDMRGSKWDLIKPLLKTLQEA
               70        80        90       100       110       120

      120       130       140       150       160       170        
pF1KB0 FPAEIHVALIIKPDNFWQKQKTNFGSSKFIFETSMVSVEGLTKLVDPSQLTEEFDGSLDY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 FPAEIHVALIIKPDNFWQKQKTNFGSSKFIFETSMVSVEGLTKLVDPSQLTEEFDGSLDY
              130       140       150       160       170       180

      180       190       200       210       220       230        
pF1KB0 NHEEWIELRLSLEEFFNSAVHLLSRLEDLQEMLARKEFPVDVEGSRRLIDEHTQLKKKVL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 NHEEWIELRLSLEEFFNSAVHLLSRLEDLQEMLARKEFPVDVEGSRRLIDEHTQLKKKVL
              190       200       210       220       230       240

      240       250       260       270       280       290        
pF1KB0 KAPVEELDREGQRLLQCIRCSDGFSGRNCIPGSADFQSLVPKITSLLDKLHSTRQHLHQM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 KAPVEELDREGQRLLQCIRCSDGFSGRNCIPGSADFQSLVPKITSLLDKLHSTRQHLHQM
              250       260       270       280       290       300

      300       310       320       330       340       350        
pF1KB0 WHVRKLKLDQCFQLRLFEQDAEKMFDWISHNKELFLQSHTEIGVSYQYALDLQTQHNHFA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 WHVRKLKLDQCFQLRLFEQDAEKMFDWISHNKELFLQSHTEIGVSYQYALDLQTQHNHFA
              310       320       330       340       350       360

      360       370       380       390       400       410        
pF1KB0 MNSMNAYVNINRIMSVASRLSEAGHYASQQIKQISTQLDQEWKSFAAALDERSTILAMSA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 MNSMNAYVNINRIMSVASRLSEAGHYASQQIKQISTQLDQEWKSFAAALDERSTILAMSA
              370       380       390       400       410       420

      420       430       440       450       460       470        
pF1KB0 VFHQKAEQFLSGVDAWCKMCSEGGLPSEMQDLELAIHHHQTLYEQVTQAYTEVSQDGKAL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 VFHQKAEQFLSGVDAWCKMCSEGGLPSEMQDLELAIHHHQTLYEQVTQAYTEVSQDGKAL
              430       440       450       460       470       480

      480       490       500       510       520       530        
pF1KB0 LDVLQRPLSPGNSESLTATANYSKAVHQVLDVVHEVLHHQRRLESIWQHRKVRLHQRLQL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LDVLQRPLSPGNSESLTATANYSKAVHQVLDVVHEVLHHQRRLESIWQHRKVRLHQRLQL
              490       500       510       520       530       540

      540       550       560       570       580       590        
pF1KB0 CVFQQDVQQVLDWIENHGEAFLSKHTGVGKSLHRARALQKRHDDFEEVAQNTYTNADKLL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 CVFQQDVQQVLDWIENHGEAFLSKHTGVGKSLHRARALQKRHDDFEEVAQNTYTNADKLL
              550       560       570       580       590       600

      600       610       620       630       640       650        
pF1KB0 EAAEQLAQTGECDPEEIYKAARHLEVRIQDFVRRVEQRKLLLDMSVSFHTHTKELWTWME
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 EAAEQLAQTGECDPEEIYKAARHLEVRIQDFVRRVEQRKLLLDMSVSFHTHTKELWTWME
              610       620       630       640       650       660

      660       670       680       690       700       710        
pF1KB0 DLQKEMLEDVCADSVDAVQELIKQFQQQQTATLDATLNVIKEGEDLIQQLRSAPPSLGEP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 DLQKEMLEDVCADSVDAVQELIKQFQQQQTATLDATLNVIKEGEDLIQQLRSAPPSLGEP
              670       680       690       700       710       720

      720       730       740       750       760       770        
pF1KB0 SEARDSAVSNNKTPHSSSISHIESVLQQLDDAQVQMEELFHERKIKLDIFLQLRIFEQYT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 SEARDSAVSNNKTPHSSSISHIESVLQQLDDAQVQMEELFHERKIKLDIFLQLRIFEQYT
              730       740       750       760       770       780

      780       790       800       810       820       830        
pF1KB0 IEVTAELDAWNEDLLRQMNDFNTEDLTLAEQRLQRHTERKLAMNNMTFEVIQQGQDLHQY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 IEVTAELDAWNEDLLRQMNDFNTEDLTLAEQRLQRHTERKLAMNNMTFEVIQQGQDLHQY
              790       800       810       820       830       840

      840       850       860       870       880       890        
pF1KB0 ITEVQASGIELICEKDIDLAAQVQELLEFLHEKQHELELNAEQTHKRLEQCLQLRHLQAE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 ITEVQASGIELICEKDIDLAAQVQELLEFLHEKQHELELNAEQTHKRLEQCLQLRHLQAE
              850       860       870       880       890       900

      900       910       920       930       940       950        
pF1KB0 VKQVLGWIRNGESMLNASLVNASSLSEAEQLQREHEQFQLAIEKTHQSALQVQQKAEVLL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 VKQVLGWIRNGESMLNASLVNASSLSEAEQLQREHEQFQLAIEKTHQSALQVQQKAEVLL
              910       920       930       940       950       960

      960       970       980       990      1000      1010        
pF1KB0 QAGHYDADAIRECAEKVALHWQQLMLKMEDRLKLVNASVAFYKTSEQVCSVLESLEQEYR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 QAGHYDADAIRECAEKVALHWQQLMLKMEDRLKLVNASVAFYKTSEQVCSVLESLEQEYR
              970       980       990      1000      1010      1020

     1020      1030      1040      1050      1060      1070        
pF1KB0 RDEDWCGGRDKLGPAAEIDHVIPLISKHLEQKEAFLKACTLARRNAEVFLKYIHRNNVSM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 RDEDWCGGRDKLGPAAEIDHVIPLISKHLEQKEAFLKACTLARRNAEVFLKYIHRNNVSM
             1030      1040      1050      1060      1070      1080

     1080      1090      1100      1110      1120      1130        
pF1KB0 PSVASHTRGPEQQVKAILSELLQRENRVLHFWTLKKRRLDQCQQYVVFERSAKQALDWIQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 PSVASHTRGPEQQVKAILSELLQRENRVLHFWTLKKRRLDQCQQYVVFERSAKQALDWIQ
             1090      1100      1110      1120      1130      1140

     1140      1150      1160      1170      1180      1190        
pF1KB0 ETGEFYLSTHTSTGETTEETQELLKEYGEFRVPAKQTKEKVKLLIQLADSFVEKGHIHAT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 ETGEFYLSTHTSTGETTEETQELLKEYGEFRVPAKQTKEKVKLLIQLADSFVEKGHIHAT
             1150      1160      1170      1180      1190      1200

     1200      1210      1220      1230      1240      1250        
pF1KB0 EIRKWVTTVDKHYRDFSLRMGKYRYSLEKALGVNTEDNKDLELDIIPASLSDREVKLRDA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 EIRKWVTTVDKHYRDFSLRMGKYRYSLEKALGVNTEDNKDLELDIIPASLSDREVKLRDA
             1210      1220      1230      1240      1250      1260

     1260      1270      1280      1290      1300      1310        
pF1KB0 NHEVNEEKRKSARKKEFIMAELLQTEKAYVRDLHECLETYLWEMTSGVEEIPPGILNKEH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 NHEVNEEKRKSARKKEFIMAELLQTEKAYVRDLHECLETYLWEMTSGVEEIPPGILNKEH
             1270      1280      1290      1300      1310      1320

     1320      1330      1340      1350      1360      1370        
pF1KB0 IIFGNIQEIYDFHNNIFLKELEKYEQLPEDVGHCFVTWADKFQMYVTYCKNKPDSNQLIL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 IIFGNIQEIYDFHNNIFLKELEKYEQLPEDVGHCFVTWADKFQMYVTYCKNKPDSNQLIL
             1330      1340      1350      1360      1370      1380

     1380      1390      1400      1410      1420      1430        
pF1KB0 EHAGTFFDEIQQRHGLANSISSYLIKPVQRITKYQLLLKELLTCCEEGKGELKDGLEVML
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 EHAGTFFDEIQQRHGLANSISSYLIKPVQRITKYQLLLKELLTCCEEGKGELKDGLEVML
             1390      1400      1410      1420      1430      1440

     1440      1450      1460      1470      1480      1490        
pF1KB0 SVPKKANDAMHVSMLEGFDENLDVQGELILQDAFQVWDPKSLIRKGRERHLFLFEISLVF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 SVPKKANDAMHVSMLEGFDENLDVQGELILQDAFQVWDPKSLIRKGRERHLFLFEISLVF
             1450      1460      1470      1480      1490      1500

     1500      1510      1520      1530      1540      1550        
pF1KB0 SKEIKDSSGHTKYVYKNKLLTSELGVTEHVEGDPCKFALWSGRTPSSDNKTVLKASNIET
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 SKEIKDSSGHTKYVYKNKLLTSELGVTEHVEGDPCKFALWSGRTPSSDNKTVLKASNIET
             1510      1520      1530      1540      1550      1560

     1560      1570      1580      1590      1600      1610        
pF1KB0 KQEWIKNIREVIQERIIHLKGALKEPLQLPKTPAKQRNNSKRDGVEDIDSQGDGSSQPDT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 KQEWIKNIREVIQERIIHLKGALKEPLQLPKTPAKQRNNSKRDGVEDIDSQGDGSSQPDT
             1570      1580      1590      1600      1610      1620

     1620      1630      1640      1650                            
pF1KB0 ISIASRTSQNTVDSDKDGNLVPRWHLGPGDPFSTYV                        
       ::::::::::::::::                                            
XP_006 ISIASRTSQNTVDSDKLSGGCELTVVLQDFSAGHSSELTIQVGQTVELLERPSERPGWCL
             1630      1640      1650      1660      1670      1680

>--
 initn: 624 init1: 215 opt: 744  Z-score: 488.2  bits: 104.1 E(85289): 1.9e-20
Smith-Waterman score: 744; 34.6% identity (66.2% similar) in 399 aa overlap (1264-1650:1914-2302)

          1240      1250      1260      1270      1280      1290   
pF1KB0 EDNKDLELDIIPASLSDREVKLRDANHEVNEEKRKSARKKEFIMAELLQTEKAYVRDLHE
                                     :.: :. : . :.. ::.:::: ::.::  
XP_006 GSSYRGSLKDPAGCLNEGMAPPTPPKNPEEEQKAKALRGRMFVLNELVQTEKDYVKDLGI
          1890      1900      1910      1920      1930      1940   

          1300        1310      1320      1330      1340      1350 
pF1KB0 CLETYLWEMTSGVEE--IPPGILNKEHIIFGNIQEIYDFHNNIFLKELEKYEQLPEDVGH
        .: .. .    .::  .:  . .:..:.::::..:::.:...:: ::::  :  . ...
XP_006 VVEGFMKR----IEEKGVPEDMRGKDKIVFGNIHQIYDWHKDFFLAELEKCIQEQDRLAQ
          1950          1960      1970      1980      1990         

            1360      1370      1380      1390      1400      1410 
pF1KB0 CFVTWADKFQMYVTYCKNKPDSNQLILEHAGTFFDEIQQRHGLANSISSYLIKPVQRITK
        :.    :...:: ::.::: :. .. :.  ..:.:..:. .   ..:..::::.:::::
XP_006 LFIKHERKLHIYVWYCQNKPRSEYIVAEY-DAYFEEVKQEINQRLTLSDFLIKPIQRITK
    2000      2010      2020       2030      2040      2050        

            1420      1430         1440      1450      1460        
pF1KB0 YQLLLKELLTCCEEGKGELKD---GLEVMLSVPKKANDAMHVSMLEGFDENLDVQGELIL
       ::::::..:   :..  : .:   ..:.:  :::. :: :... :.::. .: .::.:. 
XP_006 YQLLLKDFLRYSEKAGLECSDIEKAVELMCLVPKRCNDMMNLGRLQGFEGTLTAQGKLLQ
     2060      2070      2080      2090      2100      2110        

     1470       1480      1490      1500      1510      1520       
pF1KB0 QDAFQVWD-PKSLIRKGRERHLFLFEISLVFSKEIKDSSGHTKYVYKNKLLTSELGVTEH
       ::.: : .   ..  . .::..::::  ..::. .. .:    :..: ..  . : . :.
XP_006 QDTFYVIELDAGMQSRTKERRVFLFEQIVIFSELLRKGSLTPGYMFKRSIKMNYLVLEEN
     2120      2130      2140      2150      2160      2170        

      1530      1540      1550      1560      1570      1580       
pF1KB0 VEGDPCKFALWSGRTPSSDNKTVLKASNIETKQEWIKNIREVIQERIIHLKGALKEPLQL
       :..::::::: . .:   ....::.:.: . .: :...: .:.. .   :. ::. :.. 
XP_006 VDNDPCKFALMNRET---SERVVLQAANADIQQAWVQDINQVLETQRDFLN-ALQSPIEY
     2180      2190         2200      2210      2220       2230    

         1590      1600         1610      1620      1630      1640 
pF1KB0 PK---TPAKQRNNSKR---DGVEDIDSQGDGSSQPDTISIASRTSQNTVDSDKDGNLVPR
        .   . : .:..  :    . .  .:   :: .:   :  .        : ..:.   .
XP_006 QRKERSTAVMRSQPARLPQASPRPYSSVPAGSEKPPKGSSYNPPLPPLKISTSNGSPGFE
         2240      2250      2260      2270      2280      2290    

            1650                                                   
pF1KB0 WHLGPGDPFSTYV                                               
       .:  ::: :                                                   
XP_006 YHQ-PGDKFEASKQNDLGGCNGTSSMAVIKDYYALKENEICVSQGEVVQVLAVNQQNMCL
          2300      2310      2320      2330      2340      2350   

>>NP_001309919 (OMIM: 604605,608901) kalirin isoform 6 [  (1650 aa)
 initn: 9433 init1: 4725 opt: 9434  Z-score: 6068.5  bits: 1135.8 E(85289):    0
Smith-Waterman score: 10771; 98.7% identity (98.7% similar) in 1663 aa overlap (1-1654:1-1650)

               10        20        30        40        50        60
pF1KB0 MTDRFWDQWYLWYLRLLRLLDRGSFRNDGLKASDVLPILKEKVAFVSGGRDKRGGPILTF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MTDRFWDQWYLWYLRLLRLLDRGSFRNDGLKASDVLPILKEKVAFVSGGRDKRGGPILTF
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB0 PARSNHDRIRQEDLRKLVTYLASVPSEDVCKRGFTVIIDMRGSKWDLIKPLLKTLQEAFP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PARSNHDRIRQEDLRKLVTYLASVPSEDVCKRGFTVIIDMRGSKWDLIKPLLKTLQEAFP
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB0 AEIHVALIIKPDNFWQKQKTNFGSSKFIFETSMVSVEGLTKLVDPSQLTEEFDGSLDYNH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AEIHVALIIKPDNFWQKQKTNFGSSKFIFETSMVSVEGLTKLVDPSQLTEEFDGSLDYNH
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB0 EEWIELRLSLEEFFNSAVHLLSRLEDLQEMLARKEFPVDVEGSRRLIDEHTQLKKKVLKA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EEWIELRLSLEEFFNSAVHLLSRLEDLQEMLARKEFPVDVEGSRRLIDEHTQLKKKVLKA
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB0 PVEELDREGQRLLQCIRCSDGFSGRNCIPGSADFQSLVPKITSLLDKLHSTRQHLHQMWH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PVEELDREGQRLLQCIRCSDGFSGRNCIPGSADFQSLVPKITSLLDKLHSTRQHLHQMWH
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB0 VRKLKLDQCFQLRLFEQDAEKMFDWISHNKELFLQSHTEIGVSYQYALDLQTQHNHFAMN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VRKLKLDQCFQLRLFEQDAEKMFDWISHNKELFLQSHTEIGVSYQYALDLQTQHNHFAMN
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB0 SMNAYVNINRIMSVASRLSEAGHYASQQIKQISTQLDQEWKSFAAALDERSTILAMSAVF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SMNAYVNINRIMSVASRLSEAGHYASQQIKQISTQLDQEWKSFAAALDERSTILAMSAVF
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KB0 HQKAEQFLSGVDAWCKMCSEGGLPSEMQDLELAIHHHQTLYEQVTQAYTEVSQDGKALLD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HQKAEQFLSGVDAWCKMCSEGGLPSEMQDLELAIHHHQTLYEQVTQAYTEVSQDGKALLD
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KB0 VLQRPLSPGNSESLTATANYSKAVHQVLDVVHEVLHHQRRLESIWQHRKVRLHQRLQLCV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VLQRPLSPGNSESLTATANYSKAVHQVLDVVHEVLHHQRRLESIWQHRKVRLHQRLQLCV
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KB0 FQQDVQQVLDWIENHGEAFLSKHTGVGKSLHRARALQKRHDDFEEVAQNTYTNADKLLEA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FQQDVQQVLDWIENHGEAFLSKHTGVGKSLHRARALQKRHDDFEEVAQNTYTNADKLLEA
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KB0 AEQLAQTGECDPEEIYKAARHLEVRIQDFVRRVEQRKLLLDMSVSFHTHTKELWTWMEDL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AEQLAQTGECDPEEIYKAARHLEVRIQDFVRRVEQRKLLLDMSVSFHTHTKELWTWMEDL
              610       620       630       640       650       660

              670       680       690       700       710       720
pF1KB0 QKEMLEDVCADSVDAVQELIKQFQQQQTATLDATLNVIKEGEDLIQQLRSAPPSLGEPSE
       :::::::::::::::::::::::::::::::::::::::::::::::::           
NP_001 QKEMLEDVCADSVDAVQELIKQFQQQQTATLDATLNVIKEGEDLIQQLR-----------
              670       680       690       700                    

              730       740       750       760       770       780
pF1KB0 ARDSAVSNNKTPHSSSISHIESVLQQLDDAQVQMEELFHERKIKLDIFLQLRIFEQYTIE
         ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 --DSAVSNNKTPHSSSISHIESVLQQLDDAQVQMEELFHERKIKLDIFLQLRIFEQYTIE
       710       720       730       740       750       760       

              790       800       810       820       830       840
pF1KB0 VTAELDAWNEDLLRQMNDFNTEDLTLAEQRLQRHTERKLAMNNMTFEVIQQGQDLHQYIT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VTAELDAWNEDLLRQMNDFNTEDLTLAEQRLQRHTERKLAMNNMTFEVIQQGQDLHQYIT
       770       780       790       800       810       820       

              850       860       870       880       890       900
pF1KB0 EVQASGIELICEKDIDLAAQVQELLEFLHEKQHELELNAEQTHKRLEQCLQLRHLQAEVK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EVQASGIELICEKDIDLAAQVQELLEFLHEKQHELELNAEQTHKRLEQCLQLRHLQAEVK
       830       840       850       860       870       880       

              910       920       930       940                950 
pF1KB0 QVLGWIRNGESMLNASLVNASSLSEAEQLQREHEQFQLAIE---------KTHQSALQVQ
       :::::::::::::::::::::::::::::::::::::::::         ::::::::::
NP_001 QVLGWIRNGESMLNASLVNASSLSEAEQLQREHEQFQLAIESLFHATSLQKTHQSALQVQ
       890       900       910       920       930       940       

             960       970       980       990      1000      1010 
pF1KB0 QKAEVLLQAGHYDADAIRECAEKVALHWQQLMLKMEDRLKLVNASVAFYKTSEQVCSVLE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QKAEVLLQAGHYDADAIRECAEKVALHWQQLMLKMEDRLKLVNASVAFYKTSEQVCSVLE
       950       960       970       980       990      1000       

            1020      1030      1040      1050      1060      1070 
pF1KB0 SLEQEYRRDEDWCGGRDKLGPAAEIDHVIPLISKHLEQKEAFLKACTLARRNAEVFLKYI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SLEQEYRRDEDWCGGRDKLGPAAEIDHVIPLISKHLEQKEAFLKACTLARRNAEVFLKYI
      1010      1020      1030      1040      1050      1060       

            1080      1090      1100      1110      1120      1130 
pF1KB0 HRNNVSMPSVASHTRGPEQQVKAILSELLQRENRVLHFWTLKKRRLDQCQQYVVFERSAK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HRNNVSMPSVASHTRGPEQQVKAILSELLQRENRVLHFWTLKKRRLDQCQQYVVFERSAK
      1070      1080      1090      1100      1110      1120       

            1140      1150      1160      1170      1180      1190 
pF1KB0 QALDWIQETGEFYLSTHTSTGETTEETQELLKEYGEFRVPAKQTKEKVKLLIQLADSFVE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QALDWIQETGEFYLSTHTSTGETTEETQELLKEYGEFRVPAKQTKEKVKLLIQLADSFVE
      1130      1140      1150      1160      1170      1180       

            1200      1210      1220      1230      1240      1250 
pF1KB0 KGHIHATEIRKWVTTVDKHYRDFSLRMGKYRYSLEKALGVNTEDNKDLELDIIPASLSDR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KGHIHATEIRKWVTTVDKHYRDFSLRMGKYRYSLEKALGVNTEDNKDLELDIIPASLSDR
      1190      1200      1210      1220      1230      1240       

            1260      1270      1280      1290      1300      1310 
pF1KB0 EVKLRDANHEVNEEKRKSARKKEFIMAELLQTEKAYVRDLHECLETYLWEMTSGVEEIPP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EVKLRDANHEVNEEKRKSARKKEFIMAELLQTEKAYVRDLHECLETYLWEMTSGVEEIPP
      1250      1260      1270      1280      1290      1300       

            1320      1330      1340      1350      1360      1370 
pF1KB0 GILNKEHIIFGNIQEIYDFHNNIFLKELEKYEQLPEDVGHCFVTWADKFQMYVTYCKNKP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GILNKEHIIFGNIQEIYDFHNNIFLKELEKYEQLPEDVGHCFVTWADKFQMYVTYCKNKP
      1310      1320      1330      1340      1350      1360       

            1380      1390      1400      1410      1420      1430 
pF1KB0 DSNQLILEHAGTFFDEIQQRHGLANSISSYLIKPVQRITKYQLLLKELLTCCEEGKGELK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DSNQLILEHAGTFFDEIQQRHGLANSISSYLIKPVQRITKYQLLLKELLTCCEEGKGELK
      1370      1380      1390      1400      1410      1420       

            1440      1450      1460      1470      1480      1490 
pF1KB0 DGLEVMLSVPKKANDAMHVSMLEGFDENLDVQGELILQDAFQVWDPKSLIRKGRERHLFL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DGLEVMLSVPKKANDAMHVSMLEGFDENLDVQGELILQDAFQVWDPKSLIRKGRERHLFL
      1430      1440      1450      1460      1470      1480       

            1500      1510      1520      1530      1540      1550 
pF1KB0 FEISLVFSKEIKDSSGHTKYVYKNKLLTSELGVTEHVEGDPCKFALWSGRTPSSDNKTVL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FEISLVFSKEIKDSSGHTKYVYKNKLLTSELGVTEHVEGDPCKFALWSGRTPSSDNKTVL
      1490      1500      1510      1520      1530      1540       

            1560      1570      1580      1590      1600      1610 
pF1KB0 KASNIETKQEWIKNIREVIQERIIHLKGALKEPLQLPKTPAKQRNNSKRDGVEDIDSQGD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KASNIETKQEWIKNIREVIQERIIHLKGALKEPLQLPKTPAKQRNNSKRDGVEDIDSQGD
      1550      1560      1570      1580      1590      1600       

            1620      1630      1640      1650    
pF1KB0 GSSQPDTISIASRTSQNTVDSDKDGNLVPRWHLGPGDPFSTYV
       :::::::::::::::::::::::::::::::::::::::::::
NP_001 GSSQPDTISIASRTSQNTVDSDKDGNLVPRWHLGPGDPFSTYV
      1610      1620      1630      1640      1650

>>XP_016862923 (OMIM: 604605,608901) PREDICTED: kalirin   (1652 aa)
 initn: 9263 init1: 4725 opt: 9264  Z-score: 5959.4  bits: 1115.7 E(85289):    0
Smith-Waterman score: 10601; 98.7% identity (98.7% similar) in 1641 aa overlap (23-1654:25-1652)

                 10        20        30        40        50        
pF1KB0   MTDRFWDQWYLWYLRLLRLLDRGSFRNDGLKASDVLPILKEKVAFVSGGRDKRGGPIL
                               ::::::::::::::::::::::::::::::::::::
XP_016 MNPPEGAAEEGGAADSDVDAFFRTGSFRNDGLKASDVLPILKEKVAFVSGGRDKRGGPIL
               10        20        30        40        50        60

       60        70        80        90       100       110        
pF1KB0 TFPARSNHDRIRQEDLRKLVTYLASVPSEDVCKRGFTVIIDMRGSKWDLIKPLLKTLQEA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TFPARSNHDRIRQEDLRKLVTYLASVPSEDVCKRGFTVIIDMRGSKWDLIKPLLKTLQEA
               70        80        90       100       110       120

      120       130       140       150       160       170        
pF1KB0 FPAEIHVALIIKPDNFWQKQKTNFGSSKFIFETSMVSVEGLTKLVDPSQLTEEFDGSLDY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FPAEIHVALIIKPDNFWQKQKTNFGSSKFIFETSMVSVEGLTKLVDPSQLTEEFDGSLDY
              130       140       150       160       170       180

      180       190       200       210       220       230        
pF1KB0 NHEEWIELRLSLEEFFNSAVHLLSRLEDLQEMLARKEFPVDVEGSRRLIDEHTQLKKKVL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NHEEWIELRLSLEEFFNSAVHLLSRLEDLQEMLARKEFPVDVEGSRRLIDEHTQLKKKVL
              190       200       210       220       230       240

      240       250       260       270       280       290        
pF1KB0 KAPVEELDREGQRLLQCIRCSDGFSGRNCIPGSADFQSLVPKITSLLDKLHSTRQHLHQM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KAPVEELDREGQRLLQCIRCSDGFSGRNCIPGSADFQSLVPKITSLLDKLHSTRQHLHQM
              250       260       270       280       290       300

      300       310       320       330       340       350        
pF1KB0 WHVRKLKLDQCFQLRLFEQDAEKMFDWISHNKELFLQSHTEIGVSYQYALDLQTQHNHFA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 WHVRKLKLDQCFQLRLFEQDAEKMFDWISHNKELFLQSHTEIGVSYQYALDLQTQHNHFA
              310       320       330       340       350       360

      360       370       380       390       400       410        
pF1KB0 MNSMNAYVNINRIMSVASRLSEAGHYASQQIKQISTQLDQEWKSFAAALDERSTILAMSA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MNSMNAYVNINRIMSVASRLSEAGHYASQQIKQISTQLDQEWKSFAAALDERSTILAMSA
              370       380       390       400       410       420

      420       430       440       450       460       470        
pF1KB0 VFHQKAEQFLSGVDAWCKMCSEGGLPSEMQDLELAIHHHQTLYEQVTQAYTEVSQDGKAL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VFHQKAEQFLSGVDAWCKMCSEGGLPSEMQDLELAIHHHQTLYEQVTQAYTEVSQDGKAL
              430       440       450       460       470       480

      480       490       500       510       520       530        
pF1KB0 LDVLQRPLSPGNSESLTATANYSKAVHQVLDVVHEVLHHQRRLESIWQHRKVRLHQRLQL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LDVLQRPLSPGNSESLTATANYSKAVHQVLDVVHEVLHHQRRLESIWQHRKVRLHQRLQL
              490       500       510       520       530       540

      540       550       560       570       580       590        
pF1KB0 CVFQQDVQQVLDWIENHGEAFLSKHTGVGKSLHRARALQKRHDDFEEVAQNTYTNADKLL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CVFQQDVQQVLDWIENHGEAFLSKHTGVGKSLHRARALQKRHDDFEEVAQNTYTNADKLL
              550       560       570       580       590       600

      600       610       620       630       640       650        
pF1KB0 EAAEQLAQTGECDPEEIYKAARHLEVRIQDFVRRVEQRKLLLDMSVSFHTHTKELWTWME
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EAAEQLAQTGECDPEEIYKAARHLEVRIQDFVRRVEQRKLLLDMSVSFHTHTKELWTWME
              610       620       630       640       650       660

      660       670       680       690       700       710        
pF1KB0 DLQKEMLEDVCADSVDAVQELIKQFQQQQTATLDATLNVIKEGEDLIQQLRSAPPSLGEP
       :::::::::::::::::::::::::::::::::::::::::::::::::::         
XP_016 DLQKEMLEDVCADSVDAVQELIKQFQQQQTATLDATLNVIKEGEDLIQQLR---------
              670       680       690       700       710          

      720       730       740       750       760       770        
pF1KB0 SEARDSAVSNNKTPHSSSISHIESVLQQLDDAQVQMEELFHERKIKLDIFLQLRIFEQYT
           ::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ----DSAVSNNKTPHSSSISHIESVLQQLDDAQVQMEELFHERKIKLDIFLQLRIFEQYT
                 720       730       740       750       760       

      780       790       800       810       820       830        
pF1KB0 IEVTAELDAWNEDLLRQMNDFNTEDLTLAEQRLQRHTERKLAMNNMTFEVIQQGQDLHQY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IEVTAELDAWNEDLLRQMNDFNTEDLTLAEQRLQRHTERKLAMNNMTFEVIQQGQDLHQY
       770       780       790       800       810       820       

      840       850       860       870       880       890        
pF1KB0 ITEVQASGIELICEKDIDLAAQVQELLEFLHEKQHELELNAEQTHKRLEQCLQLRHLQAE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ITEVQASGIELICEKDIDLAAQVQELLEFLHEKQHELELNAEQTHKRLEQCLQLRHLQAE
       830       840       850       860       870       880       

      900       910       920       930       940                  
pF1KB0 VKQVLGWIRNGESMLNASLVNASSLSEAEQLQREHEQFQLAIE---------KTHQSALQ
       :::::::::::::::::::::::::::::::::::::::::::         ::::::::
XP_016 VKQVLGWIRNGESMLNASLVNASSLSEAEQLQREHEQFQLAIESLFHATSLQKTHQSALQ
       890       900       910       920       930       940       

     950       960       970       980       990      1000         
pF1KB0 VQQKAEVLLQAGHYDADAIRECAEKVALHWQQLMLKMEDRLKLVNASVAFYKTSEQVCSV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VQQKAEVLLQAGHYDADAIRECAEKVALHWQQLMLKMEDRLKLVNASVAFYKTSEQVCSV
       950       960       970       980       990      1000       

    1010      1020      1030      1040      1050      1060         
pF1KB0 LESLEQEYRRDEDWCGGRDKLGPAAEIDHVIPLISKHLEQKEAFLKACTLARRNAEVFLK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LESLEQEYRRDEDWCGGRDKLGPAAEIDHVIPLISKHLEQKEAFLKACTLARRNAEVFLK
      1010      1020      1030      1040      1050      1060       

    1070      1080      1090      1100      1110      1120         
pF1KB0 YIHRNNVSMPSVASHTRGPEQQVKAILSELLQRENRVLHFWTLKKRRLDQCQQYVVFERS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YIHRNNVSMPSVASHTRGPEQQVKAILSELLQRENRVLHFWTLKKRRLDQCQQYVVFERS
      1070      1080      1090      1100      1110      1120       

    1130      1140      1150      1160      1170      1180         
pF1KB0 AKQALDWIQETGEFYLSTHTSTGETTEETQELLKEYGEFRVPAKQTKEKVKLLIQLADSF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AKQALDWIQETGEFYLSTHTSTGETTEETQELLKEYGEFRVPAKQTKEKVKLLIQLADSF
      1130      1140      1150      1160      1170      1180       

    1190      1200      1210      1220      1230      1240         
pF1KB0 VEKGHIHATEIRKWVTTVDKHYRDFSLRMGKYRYSLEKALGVNTEDNKDLELDIIPASLS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VEKGHIHATEIRKWVTTVDKHYRDFSLRMGKYRYSLEKALGVNTEDNKDLELDIIPASLS
      1190      1200      1210      1220      1230      1240       

    1250      1260      1270      1280      1290      1300         
pF1KB0 DREVKLRDANHEVNEEKRKSARKKEFIMAELLQTEKAYVRDLHECLETYLWEMTSGVEEI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DREVKLRDANHEVNEEKRKSARKKEFIMAELLQTEKAYVRDLHECLETYLWEMTSGVEEI
      1250      1260      1270      1280      1290      1300       

    1310      1320      1330      1340      1350      1360         
pF1KB0 PPGILNKEHIIFGNIQEIYDFHNNIFLKELEKYEQLPEDVGHCFVTWADKFQMYVTYCKN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PPGILNKEHIIFGNIQEIYDFHNNIFLKELEKYEQLPEDVGHCFVTWADKFQMYVTYCKN
      1310      1320      1330      1340      1350      1360       

    1370      1380      1390      1400      1410      1420         
pF1KB0 KPDSNQLILEHAGTFFDEIQQRHGLANSISSYLIKPVQRITKYQLLLKELLTCCEEGKGE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KPDSNQLILEHAGTFFDEIQQRHGLANSISSYLIKPVQRITKYQLLLKELLTCCEEGKGE
      1370      1380      1390      1400      1410      1420       

    1430      1440      1450      1460      1470      1480         
pF1KB0 LKDGLEVMLSVPKKANDAMHVSMLEGFDENLDVQGELILQDAFQVWDPKSLIRKGRERHL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LKDGLEVMLSVPKKANDAMHVSMLEGFDENLDVQGELILQDAFQVWDPKSLIRKGRERHL
      1430      1440      1450      1460      1470      1480       

    1490      1500      1510      1520      1530      1540         
pF1KB0 FLFEISLVFSKEIKDSSGHTKYVYKNKLLTSELGVTEHVEGDPCKFALWSGRTPSSDNKT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FLFEISLVFSKEIKDSSGHTKYVYKNKLLTSELGVTEHVEGDPCKFALWSGRTPSSDNKT
      1490      1500      1510      1520      1530      1540       

    1550      1560      1570      1580      1590      1600         
pF1KB0 VLKASNIETKQEWIKNIREVIQERIIHLKGALKEPLQLPKTPAKQRNNSKRDGVEDIDSQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VLKASNIETKQEWIKNIREVIQERIIHLKGALKEPLQLPKTPAKQRNNSKRDGVEDIDSQ
      1550      1560      1570      1580      1590      1600       

    1610      1620      1630      1640      1650    
pF1KB0 GDGSSQPDTISIASRTSQNTVDSDKDGNLVPRWHLGPGDPFSTYV
       :::::::::::::::::::::::::::::::::::::::::::::
XP_016 GDGSSQPDTISIASRTSQNTVDSDKDGNLVPRWHLGPGDPFSTYV
      1610      1620      1630      1640      1650  

>>XP_006713875 (OMIM: 604605,608901) PREDICTED: kalirin   (2975 aa)
 initn: 9108 init1: 4570 opt: 9109  Z-score: 5856.1  bits: 1097.4 E(85289):    0
Smith-Waterman score: 10446; 98.6% identity (98.6% similar) in 1621 aa overlap (23-1634:25-1632)

                 10        20        30        40        50        
pF1KB0   MTDRFWDQWYLWYLRLLRLLDRGSFRNDGLKASDVLPILKEKVAFVSGGRDKRGGPIL
                               ::::::::::::::::::::::::::::::::::::
XP_006 MNPPEGAAEEGGAADSDVDAFFRTGSFRNDGLKASDVLPILKEKVAFVSGGRDKRGGPIL
               10        20        30        40        50        60

       60        70        80        90       100       110        
pF1KB0 TFPARSNHDRIRQEDLRKLVTYLASVPSEDVCKRGFTVIIDMRGSKWDLIKPLLKTLQEA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 TFPARSNHDRIRQEDLRKLVTYLASVPSEDVCKRGFTVIIDMRGSKWDLIKPLLKTLQEA
               70        80        90       100       110       120

      120       130       140       150       160       170        
pF1KB0 FPAEIHVALIIKPDNFWQKQKTNFGSSKFIFETSMVSVEGLTKLVDPSQLTEEFDGSLDY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 FPAEIHVALIIKPDNFWQKQKTNFGSSKFIFETSMVSVEGLTKLVDPSQLTEEFDGSLDY
              130       140       150       160       170       180

      180       190       200       210       220       230        
pF1KB0 NHEEWIELRLSLEEFFNSAVHLLSRLEDLQEMLARKEFPVDVEGSRRLIDEHTQLKKKVL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 NHEEWIELRLSLEEFFNSAVHLLSRLEDLQEMLARKEFPVDVEGSRRLIDEHTQLKKKVL
              190       200       210       220       230       240

      240       250       260       270       280       290        
pF1KB0 KAPVEELDREGQRLLQCIRCSDGFSGRNCIPGSADFQSLVPKITSLLDKLHSTRQHLHQM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 KAPVEELDREGQRLLQCIRCSDGFSGRNCIPGSADFQSLVPKITSLLDKLHSTRQHLHQM
              250       260       270       280       290       300

      300       310       320       330       340       350        
pF1KB0 WHVRKLKLDQCFQLRLFEQDAEKMFDWISHNKELFLQSHTEIGVSYQYALDLQTQHNHFA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 WHVRKLKLDQCFQLRLFEQDAEKMFDWISHNKELFLQSHTEIGVSYQYALDLQTQHNHFA
              310       320       330       340       350       360

      360       370       380       390       400       410        
pF1KB0 MNSMNAYVNINRIMSVASRLSEAGHYASQQIKQISTQLDQEWKSFAAALDERSTILAMSA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 MNSMNAYVNINRIMSVASRLSEAGHYASQQIKQISTQLDQEWKSFAAALDERSTILAMSA
              370       380       390       400       410       420

      420       430       440       450       460       470        
pF1KB0 VFHQKAEQFLSGVDAWCKMCSEGGLPSEMQDLELAIHHHQTLYEQVTQAYTEVSQDGKAL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 VFHQKAEQFLSGVDAWCKMCSEGGLPSEMQDLELAIHHHQTLYEQVTQAYTEVSQDGKAL
              430       440       450       460       470       480

      480       490       500       510       520       530        
pF1KB0 LDVLQRPLSPGNSESLTATANYSKAVHQVLDVVHEVLHHQRRLESIWQHRKVRLHQRLQL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LDVLQRPLSPGNSESLTATANYSKAVHQVLDVVHEVLHHQRRLESIWQHRKVRLHQRLQL
              490       500       510       520       530       540

      540       550       560       570       580       590        
pF1KB0 CVFQQDVQQVLDWIENHGEAFLSKHTGVGKSLHRARALQKRHDDFEEVAQNTYTNADKLL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 CVFQQDVQQVLDWIENHGEAFLSKHTGVGKSLHRARALQKRHDDFEEVAQNTYTNADKLL
              550       560       570       580       590       600

      600       610       620       630       640       650        
pF1KB0 EAAEQLAQTGECDPEEIYKAARHLEVRIQDFVRRVEQRKLLLDMSVSFHTHTKELWTWME
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 EAAEQLAQTGECDPEEIYKAARHLEVRIQDFVRRVEQRKLLLDMSVSFHTHTKELWTWME
              610       620       630       640       650       660

      660       670       680       690       700       710        
pF1KB0 DLQKEMLEDVCADSVDAVQELIKQFQQQQTATLDATLNVIKEGEDLIQQLRSAPPSLGEP
       :::::::::::::::::::::::::::::::::::::::::::::::::::         
XP_006 DLQKEMLEDVCADSVDAVQELIKQFQQQQTATLDATLNVIKEGEDLIQQLR---------
              670       680       690       700       710          

      720       730       740       750       760       770        
pF1KB0 SEARDSAVSNNKTPHSSSISHIESVLQQLDDAQVQMEELFHERKIKLDIFLQLRIFEQYT
           ::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 ----DSAVSNNKTPHSSSISHIESVLQQLDDAQVQMEELFHERKIKLDIFLQLRIFEQYT
                 720       730       740       750       760       

      780       790       800       810       820       830        
pF1KB0 IEVTAELDAWNEDLLRQMNDFNTEDLTLAEQRLQRHTERKLAMNNMTFEVIQQGQDLHQY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 IEVTAELDAWNEDLLRQMNDFNTEDLTLAEQRLQRHTERKLAMNNMTFEVIQQGQDLHQY
       770       780       790       800       810       820       

      840       850       860       870       880       890        
pF1KB0 ITEVQASGIELICEKDIDLAAQVQELLEFLHEKQHELELNAEQTHKRLEQCLQLRHLQAE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 ITEVQASGIELICEKDIDLAAQVQELLEFLHEKQHELELNAEQTHKRLEQCLQLRHLQAE
       830       840       850       860       870       880       

      900       910       920       930       940                  
pF1KB0 VKQVLGWIRNGESMLNASLVNASSLSEAEQLQREHEQFQLAIE---------KTHQSALQ
       :::::::::::::::::::::::::::::::::::::::::::         ::::::::
XP_006 VKQVLGWIRNGESMLNASLVNASSLSEAEQLQREHEQFQLAIESLFHATSLQKTHQSALQ
       890       900       910       920       930       940       

     950       960       970       980       990      1000         
pF1KB0 VQQKAEVLLQAGHYDADAIRECAEKVALHWQQLMLKMEDRLKLVNASVAFYKTSEQVCSV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 VQQKAEVLLQAGHYDADAIRECAEKVALHWQQLMLKMEDRLKLVNASVAFYKTSEQVCSV
       950       960       970       980       990      1000       

    1010      1020      1030      1040      1050      1060         
pF1KB0 LESLEQEYRRDEDWCGGRDKLGPAAEIDHVIPLISKHLEQKEAFLKACTLARRNAEVFLK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LESLEQEYRRDEDWCGGRDKLGPAAEIDHVIPLISKHLEQKEAFLKACTLARRNAEVFLK
      1010      1020      1030      1040      1050      1060       

    1070      1080      1090      1100      1110      1120         
pF1KB0 YIHRNNVSMPSVASHTRGPEQQVKAILSELLQRENRVLHFWTLKKRRLDQCQQYVVFERS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 YIHRNNVSMPSVASHTRGPEQQVKAILSELLQRENRVLHFWTLKKRRLDQCQQYVVFERS
      1070      1080      1090      1100      1110      1120       

    1130      1140      1150      1160      1170      1180         
pF1KB0 AKQALDWIQETGEFYLSTHTSTGETTEETQELLKEYGEFRVPAKQTKEKVKLLIQLADSF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 AKQALDWIQETGEFYLSTHTSTGETTEETQELLKEYGEFRVPAKQTKEKVKLLIQLADSF
      1130      1140      1150      1160      1170      1180       

    1190      1200      1210      1220      1230      1240         
pF1KB0 VEKGHIHATEIRKWVTTVDKHYRDFSLRMGKYRYSLEKALGVNTEDNKDLELDIIPASLS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 VEKGHIHATEIRKWVTTVDKHYRDFSLRMGKYRYSLEKALGVNTEDNKDLELDIIPASLS
      1190      1200      1210      1220      1230      1240       

    1250      1260      1270      1280      1290      1300         
pF1KB0 DREVKLRDANHEVNEEKRKSARKKEFIMAELLQTEKAYVRDLHECLETYLWEMTSGVEEI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 DREVKLRDANHEVNEEKRKSARKKEFIMAELLQTEKAYVRDLHECLETYLWEMTSGVEEI
      1250      1260      1270      1280      1290      1300       

    1310      1320      1330      1340      1350      1360         
pF1KB0 PPGILNKEHIIFGNIQEIYDFHNNIFLKELEKYEQLPEDVGHCFVTWADKFQMYVTYCKN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 PPGILNKEHIIFGNIQEIYDFHNNIFLKELEKYEQLPEDVGHCFVTWADKFQMYVTYCKN
      1310      1320      1330      1340      1350      1360       

    1370      1380      1390      1400      1410      1420         
pF1KB0 KPDSNQLILEHAGTFFDEIQQRHGLANSISSYLIKPVQRITKYQLLLKELLTCCEEGKGE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 KPDSNQLILEHAGTFFDEIQQRHGLANSISSYLIKPVQRITKYQLLLKELLTCCEEGKGE
      1370      1380      1390      1400      1410      1420       

    1430      1440      1450      1460      1470      1480         
pF1KB0 LKDGLEVMLSVPKKANDAMHVSMLEGFDENLDVQGELILQDAFQVWDPKSLIRKGRERHL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LKDGLEVMLSVPKKANDAMHVSMLEGFDENLDVQGELILQDAFQVWDPKSLIRKGRERHL
      1430      1440      1450      1460      1470      1480       

    1490      1500      1510      1520      1530      1540         
pF1KB0 FLFEISLVFSKEIKDSSGHTKYVYKNKLLTSELGVTEHVEGDPCKFALWSGRTPSSDNKT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 FLFEISLVFSKEIKDSSGHTKYVYKNKLLTSELGVTEHVEGDPCKFALWSGRTPSSDNKT
      1490      1500      1510      1520      1530      1540       

    1550      1560      1570      1580      1590      1600         
pF1KB0 VLKASNIETKQEWIKNIREVIQERIIHLKGALKEPLQLPKTPAKQRNNSKRDGVEDIDSQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 VLKASNIETKQEWIKNIREVIQERIIHLKGALKEPLQLPKTPAKQRNNSKRDGVEDIDSQ
      1550      1560      1570      1580      1590      1600       

    1610      1620      1630      1640      1650                   
pF1KB0 GDGSSQPDTISIASRTSQNTVDSDKDGNLVPRWHLGPGDPFSTYV               
       :::::::::::::::::::::::::                                   
XP_006 GDGSSQPDTISIASRTSQNTVDSDKLSGGCELTVVLQDFSAGHSSELTIQVGQTVELLER
      1610      1620      1630      1640      1650      1660       

>--
 initn: 624 init1: 215 opt: 744  Z-score: 488.2  bits: 104.1 E(85289): 1.9e-20
Smith-Waterman score: 744; 34.6% identity (66.2% similar) in 399 aa overlap (1264-1650:1910-2298)

          1240      1250      1260      1270      1280      1290   
pF1KB0 EDNKDLELDIIPASLSDREVKLRDANHEVNEEKRKSARKKEFIMAELLQTEKAYVRDLHE
                                     :.: :. : . :.. ::.:::: ::.::  
XP_006 GSSYRGSLKDPAGCLNEGMAPPTPPKNPEEEQKAKALRGRMFVLNELVQTEKDYVKDLGI
    1880      1890      1900      1910      1920      1930         

          1300        1310      1320      1330      1340      1350 
pF1KB0 CLETYLWEMTSGVEE--IPPGILNKEHIIFGNIQEIYDFHNNIFLKELEKYEQLPEDVGH
        .: .. .    .::  .:  . .:..:.::::..:::.:...:: ::::  :  . ...
XP_006 VVEGFMKR----IEEKGVPEDMRGKDKIVFGNIHQIYDWHKDFFLAELEKCIQEQDRLAQ
    1940          1950      1960      1970      1980      1990     

            1360      1370      1380      1390      1400      1410 
pF1KB0 CFVTWADKFQMYVTYCKNKPDSNQLILEHAGTFFDEIQQRHGLANSISSYLIKPVQRITK
        :.    :...:: ::.::: :. .. :.  ..:.:..:. .   ..:..::::.:::::
XP_006 LFIKHERKLHIYVWYCQNKPRSEYIVAEY-DAYFEEVKQEINQRLTLSDFLIKPIQRITK
        2000      2010      2020       2030      2040      2050    

            1420      1430         1440      1450      1460        
pF1KB0 YQLLLKELLTCCEEGKGELKD---GLEVMLSVPKKANDAMHVSMLEGFDENLDVQGELIL
       ::::::..:   :..  : .:   ..:.:  :::. :: :... :.::. .: .::.:. 
XP_006 YQLLLKDFLRYSEKAGLECSDIEKAVELMCLVPKRCNDMMNLGRLQGFEGTLTAQGKLLQ
         2060      2070      2080      2090      2100      2110    

     1470       1480      1490      1500      1510      1520       
pF1KB0 QDAFQVWD-PKSLIRKGRERHLFLFEISLVFSKEIKDSSGHTKYVYKNKLLTSELGVTEH
       ::.: : .   ..  . .::..::::  ..::. .. .:    :..: ..  . : . :.
XP_006 QDTFYVIELDAGMQSRTKERRVFLFEQIVIFSELLRKGSLTPGYMFKRSIKMNYLVLEEN
         2120      2130      2140      2150      2160      2170    

      1530      1540      1550      1560      1570      1580       
pF1KB0 VEGDPCKFALWSGRTPSSDNKTVLKASNIETKQEWIKNIREVIQERIIHLKGALKEPLQL
       :..::::::: . .:   ....::.:.: . .: :...: .:.. .   :. ::. :.. 
XP_006 VDNDPCKFALMNRET---SERVVLQAANADIQQAWVQDINQVLETQRDFLN-ALQSPIEY
         2180         2190      2200      2210      2220       2230

         1590      1600         1610      1620      1630      1640 
pF1KB0 PK---TPAKQRNNSKR---DGVEDIDSQGDGSSQPDTISIASRTSQNTVDSDKDGNLVPR
        .   . : .:..  :    . .  .:   :: .:   :  .        : ..:.   .
XP_006 QRKERSTAVMRSQPARLPQASPRPYSSVPAGSEKPPKGSSYNPPLPPLKISTSNGSPGFE
             2240      2250      2260      2270      2280      2290

            1650                                                   
pF1KB0 WHLGPGDPFSTYV                                               
       .:  ::: :                                                   
XP_006 YHQ-PGDKFEASKQNDLGGCNGTSSMAVIKDYYALKENEICVSQGEVVQVLAVNQQNMCL
              2300      2310      2320      2330      2340         

>>NP_001309921 (OMIM: 604605,608901) kalirin isoform 8 [  (1613 aa)
 initn: 10155 init1: 6206 opt: 6223  Z-score: 4008.1  bits: 754.6 E(85289): 1.6e-216
Smith-Waterman score: 10440; 96.5% identity (96.5% similar) in 1663 aa overlap (1-1654:1-1613)

               10        20        30        40        50        60
pF1KB0 MTDRFWDQWYLWYLRLLRLLDRGSFRNDGLKASDVLPILKEKVAFVSGGRDKRGGPILTF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MTDRFWDQWYLWYLRLLRLLDRGSFRNDGLKASDVLPILKEKVAFVSGGRDKRGGPILTF
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB0 PARSNHDRIRQEDLRKLVTYLASVPSEDVCKRGFTVIIDMRGSKWDLIKPLLKTLQEAFP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PARSNHDRIRQEDLRKLVTYLASVPSEDVCKRGFTVIIDMRGSKWDLIKPLLKTLQEAFP
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB0 AEIHVALIIKPDNFWQKQKTNFGSSKFIFETSMVSVEGLTKLVDPSQLTEEFDGSLDYNH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AEIHVALIIKPDNFWQKQKTNFGSSKFIFETSMVSVEGLTKLVDPSQLTEEFDGSLDYNH
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB0 EEWIELRLSLEEFFNSAVHLLSRLEDLQEMLARKEFPVDVEGSRRLIDEHTQLKKKVLKA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EEWIELRLSLEEFFNSAVHLLSRLEDLQEMLARKEFPVDVEGSRRLIDEHTQLKKKVLKA
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB0 PVEELDREGQRLLQCIRCSDGFSGRNCIPGSADFQSLVPKITSLLDKLHSTRQHLHQMWH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PVEELDREGQRLLQCIRCSDGFSGRNCIPGSADFQSLVPKITSLLDKLHSTRQHLHQMWH
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB0 VRKLKLDQCFQLRLFEQDAEKMFDWISHNKELFLQSHTEIGVSYQYALDLQTQHNHFAMN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VRKLKLDQCFQLRLFEQDAEKMFDWISHNKELFLQSHTEIGVSYQYALDLQTQHNHFAMN
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB0 SMNAYVNINRIMSVASRLSEAGHYASQQIKQISTQLDQEWKSFAAALDERSTILAMSAVF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SMNAYVNINRIMSVASRLSEAGHYASQQIKQISTQLDQEWKSFAAALDERSTILAMSAVF
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KB0 HQKAEQFLSGVDAWCKMCSEGGLPSEMQDLELAIHHHQTLYEQVTQAYTEVSQDGKALLD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HQKAEQFLSGVDAWCKMCSEGGLPSEMQDLELAIHHHQTLYEQVTQAYTEVSQDGKALLD
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KB0 VLQRPLSPGNSESLTATANYSKAVHQVLDVVHEVLHHQRRLESIWQHRKVRLHQRLQLCV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VLQRPLSPGNSESLTATANYSKAVHQVLDVVHEVLHHQRRLESIWQHRKVRLHQRLQLCV
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KB0 FQQDVQQVLDWIENHGEAFLSKHTGVGKSLHRARALQKRHDDFEEVAQNTYTNADKLLEA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FQQDVQQVLDWIENHGEAFLSKHTGVGKSLHRARALQKRHDDFEEVAQNTYTNADKLLEA
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KB0 AEQLAQTGECDPEEIYKAARHLEVRIQDFVRRVEQRKLLLDMSVSFHTHTKELWTWMEDL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AEQLAQTGECDPEEIYKAARHLEVRIQDFVRRVEQRKLLLDMSVSFHTHTKELWTWMEDL
              610       620       630       640       650       660

              670       680       690       700       710       720
pF1KB0 QKEMLEDVCADSVDAVQELIKQFQQQQTATLDATLNVIKEGEDLIQQLRSAPPSLGEPSE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QKEMLEDVCADSVDAVQELIKQFQQQQTATLDATLNVIKEGEDLIQQLRSAPPSLGEPSE
              670       680       690       700       710       720

              730       740       750       760       770       780
pF1KB0 ARDSAVSNNKTPHSSSISHIESVLQQLDDAQVQMEELFHERKIKLDIFLQLRIFEQYTIE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ARDSAVSNNKTPHSSSISHIESVLQQLDDAQVQMEELFHERKIKLDIFLQLRIFEQYTIE
              730       740       750       760       770       780

              790       800       810       820       830       840
pF1KB0 VTAELDAWNEDLLRQMNDFNTEDLTLAEQRLQRHTERKLAMNNMTFEVIQQGQDLHQYIT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VTAELDAWNEDLLRQMNDFNTEDLTLAEQRLQRHTERKLAMNNMTFEVIQQGQDLHQYIT
              790       800       810       820       830       840

              850       860       870       880       890       900
pF1KB0 EVQASGIELICEKDIDLAAQVQELLEFLHEKQHELELNAEQTHKRLEQCLQLRHLQAEVK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EVQASGIELICEKDIDLAAQVQELLEFLHEKQHELELNAEQTHKRLEQCLQLRHLQAEVK
              850       860       870       880       890       900

              910       920       930       940                950 
pF1KB0 QVLGWIRNGESMLNASLVNASSLSEAEQLQREHEQFQLAIE---------KTHQSALQVQ
       :::::::::::::::::::::::::::::::::::::::::         ::::::::::
NP_001 QVLGWIRNGESMLNASLVNASSLSEAEQLQREHEQFQLAIESLFHATSLQKTHQSALQVQ
              910       920       930       940       950       960

             960       970       980       990      1000      1010 
pF1KB0 QKAEVLLQAGHYDADAIRECAEKVALHWQQLMLKMEDRLKLVNASVAFYKTSEQVCSVLE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::      
NP_001 QKAEVLLQAGHYDADAIRECAEKVALHWQQLMLKMEDRLKLVNASVAFYKTSEQ------
              970       980       990      1000      1010          

            1020      1030      1040      1050      1060      1070 
pF1KB0 SLEQEYRRDEDWCGGRDKLGPAAEIDHVIPLISKHLEQKEAFLKACTLARRNAEVFLKYI
                                                   ::::::::::::::::
NP_001 --------------------------------------------ACTLARRNAEVFLKYI
                                                     1020      1030

            1080      1090      1100      1110      1120      1130 
pF1KB0 HRNNVSMPSVASHTRGPEQQVKAILSELLQRENRVLHFWTLKKRRLDQCQQYVVFERSAK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HRNNVSMPSVASHTRGPEQQVKAILSELLQRENRVLHFWTLKKRRLDQCQQYVVFERSAK
             1040      1050      1060      1070      1080      1090

            1140      1150      1160      1170      1180      1190 
pF1KB0 QALDWIQETGEFYLSTHTSTGETTEETQELLKEYGEFRVPAKQTKEKVKLLIQLADSFVE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QALDWIQETGEFYLSTHTSTGETTEETQELLKEYGEFRVPAKQTKEKVKLLIQLADSFVE
             1100      1110      1120      1130      1140      1150

            1200      1210      1220      1230      1240      1250 
pF1KB0 KGHIHATEIRKWVTTVDKHYRDFSLRMGKYRYSLEKALGVNTEDNKDLELDIIPASLSDR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KGHIHATEIRKWVTTVDKHYRDFSLRMGKYRYSLEKALGVNTEDNKDLELDIIPASLSDR
             1160      1170      1180      1190      1200      1210

            1260      1270      1280      1290      1300      1310 
pF1KB0 EVKLRDANHEVNEEKRKSARKKEFIMAELLQTEKAYVRDLHECLETYLWEMTSGVEEIPP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EVKLRDANHEVNEEKRKSARKKEFIMAELLQTEKAYVRDLHECLETYLWEMTSGVEEIPP
             1220      1230      1240      1250      1260      1270

            1320      1330      1340      1350      1360      1370 
pF1KB0 GILNKEHIIFGNIQEIYDFHNNIFLKELEKYEQLPEDVGHCFVTWADKFQMYVTYCKNKP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GILNKEHIIFGNIQEIYDFHNNIFLKELEKYEQLPEDVGHCFVTWADKFQMYVTYCKNKP
             1280      1290      1300      1310      1320      1330

            1380      1390      1400      1410      1420      1430 
pF1KB0 DSNQLILEHAGTFFDEIQQRHGLANSISSYLIKPVQRITKYQLLLKELLTCCEEGKGELK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DSNQLILEHAGTFFDEIQQRHGLANSISSYLIKPVQRITKYQLLLKELLTCCEEGKGELK
             1340      1350      1360      1370      1380      1390

            1440      1450      1460      1470      1480      1490 
pF1KB0 DGLEVMLSVPKKANDAMHVSMLEGFDENLDVQGELILQDAFQVWDPKSLIRKGRERHLFL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DGLEVMLSVPKKANDAMHVSMLEGFDENLDVQGELILQDAFQVWDPKSLIRKGRERHLFL
             1400      1410      1420      1430      1440      1450

            1500      1510      1520      1530      1540      1550 
pF1KB0 FEISLVFSKEIKDSSGHTKYVYKNKLLTSELGVTEHVEGDPCKFALWSGRTPSSDNKTVL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FEISLVFSKEIKDSSGHTKYVYKNKLLTSELGVTEHVEGDPCKFALWSGRTPSSDNKTVL
             1460      1470      1480      1490      1500      1510

            1560      1570      1580      1590      1600      1610 
pF1KB0 KASNIETKQEWIKNIREVIQERIIHLKGALKEPLQLPKTPAKQRNNSKRDGVEDIDSQGD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KASNIETKQEWIKNIREVIQERIIHLKGALKEPLQLPKTPAKQRNNSKRDGVEDIDSQGD
             1520      1530      1540      1550      1560      1570

            1620      1630      1640      1650    
pF1KB0 GSSQPDTISIASRTSQNTVDSDKDGNLVPRWHLGPGDPFSTYV
       :::::::::::::::::::::::::::::::::::::::::::
NP_001 GSSQPDTISIASRTSQNTVDSDKDGNLVPRWHLGPGDPFSTYV
             1580      1590      1600      1610   

>>NP_003938 (OMIM: 604605,608901) kalirin isoform 2 [Hom  (1663 aa)
 initn: 6206 init1: 6206 opt: 6223  Z-score: 4007.9  bits: 754.6 E(85289): 1.7e-216
Smith-Waterman score: 10894; 99.5% identity (99.5% similar) in 1663 aa overlap (1-1654:1-1663)

               10        20        30        40        50        60
pF1KB0 MTDRFWDQWYLWYLRLLRLLDRGSFRNDGLKASDVLPILKEKVAFVSGGRDKRGGPILTF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 MTDRFWDQWYLWYLRLLRLLDRGSFRNDGLKASDVLPILKEKVAFVSGGRDKRGGPILTF
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB0 PARSNHDRIRQEDLRKLVTYLASVPSEDVCKRGFTVIIDMRGSKWDLIKPLLKTLQEAFP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 PARSNHDRIRQEDLRKLVTYLASVPSEDVCKRGFTVIIDMRGSKWDLIKPLLKTLQEAFP
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB0 AEIHVALIIKPDNFWQKQKTNFGSSKFIFETSMVSVEGLTKLVDPSQLTEEFDGSLDYNH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 AEIHVALIIKPDNFWQKQKTNFGSSKFIFETSMVSVEGLTKLVDPSQLTEEFDGSLDYNH
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB0 EEWIELRLSLEEFFNSAVHLLSRLEDLQEMLARKEFPVDVEGSRRLIDEHTQLKKKVLKA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 EEWIELRLSLEEFFNSAVHLLSRLEDLQEMLARKEFPVDVEGSRRLIDEHTQLKKKVLKA
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB0 PVEELDREGQRLLQCIRCSDGFSGRNCIPGSADFQSLVPKITSLLDKLHSTRQHLHQMWH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 PVEELDREGQRLLQCIRCSDGFSGRNCIPGSADFQSLVPKITSLLDKLHSTRQHLHQMWH
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB0 VRKLKLDQCFQLRLFEQDAEKMFDWISHNKELFLQSHTEIGVSYQYALDLQTQHNHFAMN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 VRKLKLDQCFQLRLFEQDAEKMFDWISHNKELFLQSHTEIGVSYQYALDLQTQHNHFAMN
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB0 SMNAYVNINRIMSVASRLSEAGHYASQQIKQISTQLDQEWKSFAAALDERSTILAMSAVF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 SMNAYVNINRIMSVASRLSEAGHYASQQIKQISTQLDQEWKSFAAALDERSTILAMSAVF
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KB0 HQKAEQFLSGVDAWCKMCSEGGLPSEMQDLELAIHHHQTLYEQVTQAYTEVSQDGKALLD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 HQKAEQFLSGVDAWCKMCSEGGLPSEMQDLELAIHHHQTLYEQVTQAYTEVSQDGKALLD
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KB0 VLQRPLSPGNSESLTATANYSKAVHQVLDVVHEVLHHQRRLESIWQHRKVRLHQRLQLCV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 VLQRPLSPGNSESLTATANYSKAVHQVLDVVHEVLHHQRRLESIWQHRKVRLHQRLQLCV
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KB0 FQQDVQQVLDWIENHGEAFLSKHTGVGKSLHRARALQKRHDDFEEVAQNTYTNADKLLEA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 FQQDVQQVLDWIENHGEAFLSKHTGVGKSLHRARALQKRHDDFEEVAQNTYTNADKLLEA
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KB0 AEQLAQTGECDPEEIYKAARHLEVRIQDFVRRVEQRKLLLDMSVSFHTHTKELWTWMEDL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 AEQLAQTGECDPEEIYKAARHLEVRIQDFVRRVEQRKLLLDMSVSFHTHTKELWTWMEDL
              610       620       630       640       650       660

              670       680       690       700       710       720
pF1KB0 QKEMLEDVCADSVDAVQELIKQFQQQQTATLDATLNVIKEGEDLIQQLRSAPPSLGEPSE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 QKEMLEDVCADSVDAVQELIKQFQQQQTATLDATLNVIKEGEDLIQQLRSAPPSLGEPSE
              670       680       690       700       710       720

              730       740       750       760       770       780
pF1KB0 ARDSAVSNNKTPHSSSISHIESVLQQLDDAQVQMEELFHERKIKLDIFLQLRIFEQYTIE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 ARDSAVSNNKTPHSSSISHIESVLQQLDDAQVQMEELFHERKIKLDIFLQLRIFEQYTIE
              730       740       750       760       770       780

              790       800       810       820       830       840
pF1KB0 VTAELDAWNEDLLRQMNDFNTEDLTLAEQRLQRHTERKLAMNNMTFEVIQQGQDLHQYIT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 VTAELDAWNEDLLRQMNDFNTEDLTLAEQRLQRHTERKLAMNNMTFEVIQQGQDLHQYIT
              790       800       810       820       830       840

              850       860       870       880       890       900
pF1KB0 EVQASGIELICEKDIDLAAQVQELLEFLHEKQHELELNAEQTHKRLEQCLQLRHLQAEVK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 EVQASGIELICEKDIDLAAQVQELLEFLHEKQHELELNAEQTHKRLEQCLQLRHLQAEVK
              850       860       870       880       890       900

              910       920       930       940                950 
pF1KB0 QVLGWIRNGESMLNASLVNASSLSEAEQLQREHEQFQLAIE---------KTHQSALQVQ
       :::::::::::::::::::::::::::::::::::::::::         ::::::::::
NP_003 QVLGWIRNGESMLNASLVNASSLSEAEQLQREHEQFQLAIESLFHATSLQKTHQSALQVQ
              910       920       930       940       950       960

             960       970       980       990      1000      1010 
pF1KB0 QKAEVLLQAGHYDADAIRECAEKVALHWQQLMLKMEDRLKLVNASVAFYKTSEQVCSVLE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 QKAEVLLQAGHYDADAIRECAEKVALHWQQLMLKMEDRLKLVNASVAFYKTSEQVCSVLE
              970       980       990      1000      1010      1020

            1020      1030      1040      1050      1060      1070 
pF1KB0 SLEQEYRRDEDWCGGRDKLGPAAEIDHVIPLISKHLEQKEAFLKACTLARRNAEVFLKYI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 SLEQEYRRDEDWCGGRDKLGPAAEIDHVIPLISKHLEQKEAFLKACTLARRNAEVFLKYI
             1030      1040      1050      1060      1070      1080

            1080      1090      1100      1110      1120      1130 
pF1KB0 HRNNVSMPSVASHTRGPEQQVKAILSELLQRENRVLHFWTLKKRRLDQCQQYVVFERSAK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 HRNNVSMPSVASHTRGPEQQVKAILSELLQRENRVLHFWTLKKRRLDQCQQYVVFERSAK
             1090      1100      1110      1120      1130      1140

            1140      1150      1160      1170      1180      1190 
pF1KB0 QALDWIQETGEFYLSTHTSTGETTEETQELLKEYGEFRVPAKQTKEKVKLLIQLADSFVE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 QALDWIQETGEFYLSTHTSTGETTEETQELLKEYGEFRVPAKQTKEKVKLLIQLADSFVE
             1150      1160      1170      1180      1190      1200

            1200      1210      1220      1230      1240      1250 
pF1KB0 KGHIHATEIRKWVTTVDKHYRDFSLRMGKYRYSLEKALGVNTEDNKDLELDIIPASLSDR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 KGHIHATEIRKWVTTVDKHYRDFSLRMGKYRYSLEKALGVNTEDNKDLELDIIPASLSDR
             1210      1220      1230      1240      1250      1260

            1260      1270      1280      1290      1300      1310 
pF1KB0 EVKLRDANHEVNEEKRKSARKKEFIMAELLQTEKAYVRDLHECLETYLWEMTSGVEEIPP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 EVKLRDANHEVNEEKRKSARKKEFIMAELLQTEKAYVRDLHECLETYLWEMTSGVEEIPP
             1270      1280      1290      1300      1310      1320

            1320      1330      1340      1350      1360      1370 
pF1KB0 GILNKEHIIFGNIQEIYDFHNNIFLKELEKYEQLPEDVGHCFVTWADKFQMYVTYCKNKP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 GILNKEHIIFGNIQEIYDFHNNIFLKELEKYEQLPEDVGHCFVTWADKFQMYVTYCKNKP
             1330      1340      1350      1360      1370      1380

            1380      1390      1400      1410      1420      1430 
pF1KB0 DSNQLILEHAGTFFDEIQQRHGLANSISSYLIKPVQRITKYQLLLKELLTCCEEGKGELK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 DSNQLILEHAGTFFDEIQQRHGLANSISSYLIKPVQRITKYQLLLKELLTCCEEGKGELK
             1390      1400      1410      1420      1430      1440

            1440      1450      1460      1470      1480      1490 
pF1KB0 DGLEVMLSVPKKANDAMHVSMLEGFDENLDVQGELILQDAFQVWDPKSLIRKGRERHLFL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 DGLEVMLSVPKKANDAMHVSMLEGFDENLDVQGELILQDAFQVWDPKSLIRKGRERHLFL
             1450      1460      1470      1480      1490      1500

            1500      1510      1520      1530      1540      1550 
pF1KB0 FEISLVFSKEIKDSSGHTKYVYKNKLLTSELGVTEHVEGDPCKFALWSGRTPSSDNKTVL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 FEISLVFSKEIKDSSGHTKYVYKNKLLTSELGVTEHVEGDPCKFALWSGRTPSSDNKTVL
             1510      1520      1530      1540      1550      1560

            1560      1570      1580      1590      1600      1610 
pF1KB0 KASNIETKQEWIKNIREVIQERIIHLKGALKEPLQLPKTPAKQRNNSKRDGVEDIDSQGD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 KASNIETKQEWIKNIREVIQERIIHLKGALKEPLQLPKTPAKQRNNSKRDGVEDIDSQGD
             1570      1580      1590      1600      1610      1620

            1620      1630      1640      1650    
pF1KB0 GSSQPDTISIASRTSQNTVDSDKDGNLVPRWHLGPGDPFSTYV
       :::::::::::::::::::::::::::::::::::::::::::
NP_003 GSSQPDTISIASRTSQNTVDSDKDGNLVPRWHLGPGDPFSTYV
             1630      1640      1650      1660   

>>NP_001309917 (OMIM: 604605,608901) kalirin isoform 4 [  (2396 aa)
 initn: 6621 init1: 6206 opt: 6223  Z-score: 4005.5  bits: 754.7 E(85289): 2.3e-216
Smith-Waterman score: 10739; 99.5% identity (99.5% similar) in 1643 aa overlap (1-1634:1-1643)

               10        20        30        40        50        60
pF1KB0 MTDRFWDQWYLWYLRLLRLLDRGSFRNDGLKASDVLPILKEKVAFVSGGRDKRGGPILTF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MTDRFWDQWYLWYLRLLRLLDRGSFRNDGLKASDVLPILKEKVAFVSGGRDKRGGPILTF
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB0 PARSNHDRIRQEDLRKLVTYLASVPSEDVCKRGFTVIIDMRGSKWDLIKPLLKTLQEAFP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PARSNHDRIRQEDLRKLVTYLASVPSEDVCKRGFTVIIDMRGSKWDLIKPLLKTLQEAFP
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB0 AEIHVALIIKPDNFWQKQKTNFGSSKFIFETSMVSVEGLTKLVDPSQLTEEFDGSLDYNH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AEIHVALIIKPDNFWQKQKTNFGSSKFIFETSMVSVEGLTKLVDPSQLTEEFDGSLDYNH
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB0 EEWIELRLSLEEFFNSAVHLLSRLEDLQEMLARKEFPVDVEGSRRLIDEHTQLKKKVLKA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EEWIELRLSLEEFFNSAVHLLSRLEDLQEMLARKEFPVDVEGSRRLIDEHTQLKKKVLKA
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB0 PVEELDREGQRLLQCIRCSDGFSGRNCIPGSADFQSLVPKITSLLDKLHSTRQHLHQMWH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PVEELDREGQRLLQCIRCSDGFSGRNCIPGSADFQSLVPKITSLLDKLHSTRQHLHQMWH
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB0 VRKLKLDQCFQLRLFEQDAEKMFDWISHNKELFLQSHTEIGVSYQYALDLQTQHNHFAMN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VRKLKLDQCFQLRLFEQDAEKMFDWISHNKELFLQSHTEIGVSYQYALDLQTQHNHFAMN
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB0 SMNAYVNINRIMSVASRLSEAGHYASQQIKQISTQLDQEWKSFAAALDERSTILAMSAVF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SMNAYVNINRIMSVASRLSEAGHYASQQIKQISTQLDQEWKSFAAALDERSTILAMSAVF
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KB0 HQKAEQFLSGVDAWCKMCSEGGLPSEMQDLELAIHHHQTLYEQVTQAYTEVSQDGKALLD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HQKAEQFLSGVDAWCKMCSEGGLPSEMQDLELAIHHHQTLYEQVTQAYTEVSQDGKALLD
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KB0 VLQRPLSPGNSESLTATANYSKAVHQVLDVVHEVLHHQRRLESIWQHRKVRLHQRLQLCV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VLQRPLSPGNSESLTATANYSKAVHQVLDVVHEVLHHQRRLESIWQHRKVRLHQRLQLCV
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KB0 FQQDVQQVLDWIENHGEAFLSKHTGVGKSLHRARALQKRHDDFEEVAQNTYTNADKLLEA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FQQDVQQVLDWIENHGEAFLSKHTGVGKSLHRARALQKRHDDFEEVAQNTYTNADKLLEA
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KB0 AEQLAQTGECDPEEIYKAARHLEVRIQDFVRRVEQRKLLLDMSVSFHTHTKELWTWMEDL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AEQLAQTGECDPEEIYKAARHLEVRIQDFVRRVEQRKLLLDMSVSFHTHTKELWTWMEDL
              610       620       630       640       650       660

              670       680       690       700       710       720
pF1KB0 QKEMLEDVCADSVDAVQELIKQFQQQQTATLDATLNVIKEGEDLIQQLRSAPPSLGEPSE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QKEMLEDVCADSVDAVQELIKQFQQQQTATLDATLNVIKEGEDLIQQLRSAPPSLGEPSE
              670       680       690       700       710       720

              730       740       750       760       770       780
pF1KB0 ARDSAVSNNKTPHSSSISHIESVLQQLDDAQVQMEELFHERKIKLDIFLQLRIFEQYTIE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ARDSAVSNNKTPHSSSISHIESVLQQLDDAQVQMEELFHERKIKLDIFLQLRIFEQYTIE
              730       740       750       760       770       780

              790       800       810       820       830       840
pF1KB0 VTAELDAWNEDLLRQMNDFNTEDLTLAEQRLQRHTERKLAMNNMTFEVIQQGQDLHQYIT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VTAELDAWNEDLLRQMNDFNTEDLTLAEQRLQRHTERKLAMNNMTFEVIQQGQDLHQYIT
              790       800       810       820       830       840

              850       860       870       880       890       900
pF1KB0 EVQASGIELICEKDIDLAAQVQELLEFLHEKQHELELNAEQTHKRLEQCLQLRHLQAEVK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EVQASGIELICEKDIDLAAQVQELLEFLHEKQHELELNAEQTHKRLEQCLQLRHLQAEVK
              850       860       870       880       890       900

              910       920       930       940                950 
pF1KB0 QVLGWIRNGESMLNASLVNASSLSEAEQLQREHEQFQLAIE---------KTHQSALQVQ
       :::::::::::::::::::::::::::::::::::::::::         ::::::::::
NP_001 QVLGWIRNGESMLNASLVNASSLSEAEQLQREHEQFQLAIESLFHATSLQKTHQSALQVQ
              910       920       930       940       950       960

             960       970       980       990      1000      1010 
pF1KB0 QKAEVLLQAGHYDADAIRECAEKVALHWQQLMLKMEDRLKLVNASVAFYKTSEQVCSVLE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QKAEVLLQAGHYDADAIRECAEKVALHWQQLMLKMEDRLKLVNASVAFYKTSEQVCSVLE
              970       980       990      1000      1010      1020

            1020      1030      1040      1050      1060      1070 
pF1KB0 SLEQEYRRDEDWCGGRDKLGPAAEIDHVIPLISKHLEQKEAFLKACTLARRNAEVFLKYI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SLEQEYRRDEDWCGGRDKLGPAAEIDHVIPLISKHLEQKEAFLKACTLARRNAEVFLKYI
             1030      1040      1050      1060      1070      1080

            1080      1090      1100      1110      1120      1130 
pF1KB0 HRNNVSMPSVASHTRGPEQQVKAILSELLQRENRVLHFWTLKKRRLDQCQQYVVFERSAK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HRNNVSMPSVASHTRGPEQQVKAILSELLQRENRVLHFWTLKKRRLDQCQQYVVFERSAK
             1090      1100      1110      1120      1130      1140

            1140      1150      1160      1170      1180      1190 
pF1KB0 QALDWIQETGEFYLSTHTSTGETTEETQELLKEYGEFRVPAKQTKEKVKLLIQLADSFVE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QALDWIQETGEFYLSTHTSTGETTEETQELLKEYGEFRVPAKQTKEKVKLLIQLADSFVE
             1150      1160      1170      1180      1190      1200

            1200      1210      1220      1230      1240      1250 
pF1KB0 KGHIHATEIRKWVTTVDKHYRDFSLRMGKYRYSLEKALGVNTEDNKDLELDIIPASLSDR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KGHIHATEIRKWVTTVDKHYRDFSLRMGKYRYSLEKALGVNTEDNKDLELDIIPASLSDR
             1210      1220      1230      1240      1250      1260

            1260      1270      1280      1290      1300      1310 
pF1KB0 EVKLRDANHEVNEEKRKSARKKEFIMAELLQTEKAYVRDLHECLETYLWEMTSGVEEIPP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EVKLRDANHEVNEEKRKSARKKEFIMAELLQTEKAYVRDLHECLETYLWEMTSGVEEIPP
             1270      1280      1290      1300      1310      1320

            1320      1330      1340      1350      1360      1370 
pF1KB0 GILNKEHIIFGNIQEIYDFHNNIFLKELEKYEQLPEDVGHCFVTWADKFQMYVTYCKNKP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GILNKEHIIFGNIQEIYDFHNNIFLKELEKYEQLPEDVGHCFVTWADKFQMYVTYCKNKP
             1330      1340      1350      1360      1370      1380

            1380      1390      1400      1410      1420      1430 
pF1KB0 DSNQLILEHAGTFFDEIQQRHGLANSISSYLIKPVQRITKYQLLLKELLTCCEEGKGELK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DSNQLILEHAGTFFDEIQQRHGLANSISSYLIKPVQRITKYQLLLKELLTCCEEGKGELK
             1390      1400      1410      1420      1430      1440

            1440      1450      1460      1470      1480      1490 
pF1KB0 DGLEVMLSVPKKANDAMHVSMLEGFDENLDVQGELILQDAFQVWDPKSLIRKGRERHLFL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DGLEVMLSVPKKANDAMHVSMLEGFDENLDVQGELILQDAFQVWDPKSLIRKGRERHLFL
             1450      1460      1470      1480      1490      1500

            1500      1510      1520      1530      1540      1550 
pF1KB0 FEISLVFSKEIKDSSGHTKYVYKNKLLTSELGVTEHVEGDPCKFALWSGRTPSSDNKTVL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FEISLVFSKEIKDSSGHTKYVYKNKLLTSELGVTEHVEGDPCKFALWSGRTPSSDNKTVL
             1510      1520      1530      1540      1550      1560

            1560      1570      1580      1590      1600      1610 
pF1KB0 KASNIETKQEWIKNIREVIQERIIHLKGALKEPLQLPKTPAKQRNNSKRDGVEDIDSQGD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KASNIETKQEWIKNIREVIQERIIHLKGALKEPLQLPKTPAKQRNNSKRDGVEDIDSQGD
             1570      1580      1590      1600      1610      1620

            1620      1630      1640      1650                     
pF1KB0 GSSQPDTISIASRTSQNTVDSDKDGNLVPRWHLGPGDPFSTYV                 
       :::::::::::::::::::::::                                     
NP_001 GSSQPDTISIASRTSQNTVDSDKLSGGCELTVVLQDFSAGHSSELTIQVGQTVELLERPS
             1630      1640      1650      1660      1670      1680

>--
 initn: 644 init1: 215 opt: 744  Z-score: 489.6  bits: 104.1 E(85289): 1.6e-20
Smith-Waterman score: 744; 34.6% identity (66.2% similar) in 399 aa overlap (1264-1650:1920-2308)

          1240      1250      1260      1270      1280      1290   
pF1KB0 EDNKDLELDIIPASLSDREVKLRDANHEVNEEKRKSARKKEFIMAELLQTEKAYVRDLHE
                                     :.: :. : . :.. ::.:::: ::.::  
NP_001 GSSYRGSLKDPAGCLNEGMAPPTPPKNPEEEQKAKALRGRMFVLNELVQTEKDYVKDLGI
    1890      1900      1910      1920      1930      1940         

          1300        1310      1320      1330      1340      1350 
pF1KB0 CLETYLWEMTSGVEE--IPPGILNKEHIIFGNIQEIYDFHNNIFLKELEKYEQLPEDVGH
        .: .. .    .::  .:  . .:..:.::::..:::.:...:: ::::  :  . ...
NP_001 VVEGFMKR----IEEKGVPEDMRGKDKIVFGNIHQIYDWHKDFFLAELEKCIQEQDRLAQ
    1950          1960      1970      1980      1990      2000     

            1360      1370      1380      1390      1400      1410 
pF1KB0 CFVTWADKFQMYVTYCKNKPDSNQLILEHAGTFFDEIQQRHGLANSISSYLIKPVQRITK
        :.    :...:: ::.::: :. .. :.  ..:.:..:. .   ..:..::::.:::::
NP_001 LFIKHERKLHIYVWYCQNKPRSEYIVAEY-DAYFEEVKQEINQRLTLSDFLIKPIQRITK
        2010      2020      2030       2040      2050      2060    

            1420      1430         1440      1450      1460        
pF1KB0 YQLLLKELLTCCEEGKGELKD---GLEVMLSVPKKANDAMHVSMLEGFDENLDVQGELIL
       ::::::..:   :..  : .:   ..:.:  :::. :: :... :.::. .: .::.:. 
NP_001 YQLLLKDFLRYSEKAGLECSDIEKAVELMCLVPKRCNDMMNLGRLQGFEGTLTAQGKLLQ
         2070      2080      2090      2100      2110      2120    

     1470       1480      1490      1500      1510      1520       
pF1KB0 QDAFQVWD-PKSLIRKGRERHLFLFEISLVFSKEIKDSSGHTKYVYKNKLLTSELGVTEH
       ::.: : .   ..  . .::..::::  ..::. .. .:    :..: ..  . : . :.
NP_001 QDTFYVIELDAGMQSRTKERRVFLFEQIVIFSELLRKGSLTPGYMFKRSIKMNYLVLEEN
         2130      2140      2150      2160      2170      2180    

      1530      1540      1550      1560      1570      1580       
pF1KB0 VEGDPCKFALWSGRTPSSDNKTVLKASNIETKQEWIKNIREVIQERIIHLKGALKEPLQL
       :..::::::: . .:   ....::.:.: . .: :...: .:.. .   :. ::. :.. 
NP_001 VDNDPCKFALMNRET---SERVVLQAANADIQQAWVQDINQVLETQRDFLN-ALQSPIEY
         2190         2200      2210      2220      2230       2240

         1590      1600         1610      1620      1630      1640 
pF1KB0 PK---TPAKQRNNSKR---DGVEDIDSQGDGSSQPDTISIASRTSQNTVDSDKDGNLVPR
        .   . : .:..  :    . .  .:   :: .:   :  .        : ..:.   .
NP_001 QRKERSTAVMRSQPARLPQASPRPYSSVPAGSEKPPKGSSYNPPLPPLKISTSNGSPGFE
             2250      2260      2270      2280      2290      2300

            1650                                                   
pF1KB0 WHLGPGDPFSTYV                                               
       .:  ::: :                                                   
NP_001 YHQ-PGDKFEASKNDLGGCNGTSSMAVIKDYYALKENEICVSQGEVVQVLAVNQQNMCLV
              2310      2320      2330      2340      2350         




1654 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Wed Nov  2 22:31:05 2016 done: Wed Nov  2 22:31:08 2016
 Total Scan time: 17.990 Total Display time:  1.300

Function used was FASTA [36.3.4 Apr, 2011]
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