Result of FASTA (omim) for pF1KA1478
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KA1478, 632 aa
  1>>>pF1KA1478 632 - 632 aa - 632 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 7.0548+/-0.000404; mu= 11.7595+/- 0.025
 mean_var=134.0953+/-27.446, 0's: 0 Z-trim(116.0): 404  B-trim: 298 in 1/53
 Lambda= 0.110756
 statistics sampled from 26396 (26832) to 26396 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.663), E-opt: 0.2 (0.315), width:  16
 Scan time: 11.280

The best scores are:                                      opt bits E(85289)
NP_001119576 (OMIM: 604980) rac GTPase-activating  ( 632) 4147 674.6 2.9e-193
NP_001306932 (OMIM: 604980) rac GTPase-activating  ( 632) 4147 674.6 2.9e-193
XP_011536540 (OMIM: 604980) PREDICTED: rac GTPase- ( 632) 4147 674.6 2.9e-193
XP_006719422 (OMIM: 604980) PREDICTED: rac GTPase- ( 632) 4147 674.6 2.9e-193
NP_001306930 (OMIM: 604980) rac GTPase-activating  ( 632) 4147 674.6 2.9e-193
NP_037409 (OMIM: 604980) rac GTPase-activating pro ( 632) 4147 674.6 2.9e-193
NP_001119575 (OMIM: 604980) rac GTPase-activating  ( 632) 4147 674.6 2.9e-193
NP_001306928 (OMIM: 604980) rac GTPase-activating  ( 632) 4147 674.6 2.9e-193
XP_016874709 (OMIM: 604980) PREDICTED: rac GTPase- ( 632) 4147 674.6 2.9e-193
NP_001306931 (OMIM: 604980) rac GTPase-activating  ( 632) 4147 674.6 2.9e-193
NP_001306929 (OMIM: 604980) rac GTPase-activating  ( 632) 4147 674.6 2.9e-193
NP_001306933 (OMIM: 604980) rac GTPase-activating  ( 632) 4147 674.6 2.9e-193
NP_001306935 (OMIM: 604980) rac GTPase-activating  ( 644) 4147 674.6 2.9e-193
NP_001306934 (OMIM: 604980) rac GTPase-activating  ( 574) 3765 613.5 6.3e-175
NP_001306936 (OMIM: 604980) rac GTPase-activating  ( 558) 3528 575.7 1.5e-163
XP_011536545 (OMIM: 604980) PREDICTED: rac GTPase- ( 558) 3528 575.7 1.5e-163
XP_016874710 (OMIM: 604980) PREDICTED: rac GTPase- ( 558) 3528 575.7 1.5e-163
XP_016874713 (OMIM: 604980) PREDICTED: rac GTPase- ( 558) 3528 575.7 1.5e-163
XP_016874712 (OMIM: 604980) PREDICTED: rac GTPase- ( 558) 3528 575.7 1.5e-163
XP_016874715 (OMIM: 604980) PREDICTED: rac GTPase- ( 558) 3528 575.7 1.5e-163
XP_016874716 (OMIM: 604980) PREDICTED: rac GTPase- ( 558) 3528 575.7 1.5e-163
XP_016874711 (OMIM: 604980) PREDICTED: rac GTPase- ( 558) 3528 575.7 1.5e-163
XP_016874714 (OMIM: 604980) PREDICTED: rac GTPase- ( 558) 3528 575.7 1.5e-163
NP_001193531 (OMIM: 118423,604356) N-chimaerin iso ( 334)  444 82.7 2.3e-15
NP_001813 (OMIM: 118423,604356) N-chimaerin isofor ( 459)  444 82.8 2.9e-15
NP_001020372 (OMIM: 118423,604356) N-chimaerin iso ( 433)  437 81.7 6.1e-15
NP_001035025 (OMIM: 602857) beta-chimaerin isoform ( 332)  421 79.0 2.9e-14
NP_001280000 (OMIM: 602857) beta-chimaerin isoform ( 433)  421 79.1 3.6e-14
NP_001280001 (OMIM: 602857) beta-chimaerin isoform ( 453)  421 79.1 3.7e-14
NP_004058 (OMIM: 602857) beta-chimaerin isoform 2  ( 468)  421 79.1 3.8e-14
NP_001279999 (OMIM: 602857) beta-chimaerin isoform ( 481)  421 79.1 3.9e-14
XP_011513409 (OMIM: 602857) PREDICTED: beta-chimae ( 494)  421 79.2   4e-14
XP_016867211 (OMIM: 602857) PREDICTED: beta-chimae ( 500)  421 79.2   4e-14
NP_001279998 (OMIM: 602857) beta-chimaerin isoform ( 543)  421 79.2 4.3e-14
XP_011513408 (OMIM: 602857) PREDICTED: beta-chimae ( 556)  421 79.2 4.3e-14
XP_011513407 (OMIM: 602857) PREDICTED: beta-chimae ( 569)  421 79.2 4.4e-14
XP_016867210 (OMIM: 602857) PREDICTED: beta-chimae ( 575)  421 79.2 4.5e-14
NP_001280002 (OMIM: 602857) beta-chimaerin isoform ( 287)  414 77.9 5.6e-14
NP_001123537 (OMIM: 602129,609753) unconventional  (2022)  423 79.9 9.5e-14
NP_004136 (OMIM: 602129,609753) unconventional myo (2157)  423 79.9   1e-13
NP_001280010 (OMIM: 602857) beta-chimaerin isoform ( 261)  406 76.6 1.3e-13
NP_001243776 (OMIM: 600365) active breakpoint clus ( 310)  357 68.8 3.3e-11
NP_001269078 (OMIM: 600365) active breakpoint clus ( 641)  357 69.0 5.8e-11
NP_001309769 (OMIM: 600365) active breakpoint clus ( 813)  357 69.1   7e-11
NP_001153218 (OMIM: 600365) active breakpoint clus ( 813)  357 69.1   7e-11
NP_001083 (OMIM: 600365) active breakpoint cluster ( 822)  357 69.1 7.1e-11
NP_068781 (OMIM: 600365) active breakpoint cluster ( 859)  357 69.1 7.3e-11
XP_011538307 (OMIM: 610585) PREDICTED: rho GTPase- ( 624)  353 68.4 8.9e-11
XP_005270071 (OMIM: 610585) PREDICTED: rho GTPase- ( 624)  353 68.4 8.9e-11
XP_005268459 (OMIM: 605370,607785) PREDICTED: rho  ( 722)  354 68.6 8.9e-11


>>NP_001119576 (OMIM: 604980) rac GTPase-activating prot  (632 aa)
 initn: 4147 init1: 4147 opt: 4147  Z-score: 3590.8  bits: 674.6 E(85289): 2.9e-193
Smith-Waterman score: 4147; 100.0% identity (100.0% similar) in 632 aa overlap (1-632:1-632)

               10        20        30        40        50        60
pF1KA1 MDTMMLNVRNLFEQLVRRVEILSEGNEVQFIQLAKDFEDFRKKWQRTDHELGKYKDLLMK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MDTMMLNVRNLFEQLVRRVEILSEGNEVQFIQLAKDFEDFRKKWQRTDHELGKYKDLLMK
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KA1 AETERSALDVKLKHARNQVDVEIKRRQRAEADCEKLERQIQLIREMLMCDTSGSIQLSEE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AETERSALDVKLKHARNQVDVEIKRRQRAEADCEKLERQIQLIREMLMCDTSGSIQLSEE
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KA1 QKSALAFLNRGQPSSSNAGNKRLSTIDESGSILSDISFDKTDESLDWDSSLVKTFKLKKR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QKSALAFLNRGQPSSSNAGNKRLSTIDESGSILSDISFDKTDESLDWDSSLVKTFKLKKR
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KA1 EKRRSTSRQFVDGPPGPVKKTRSIGSAVDQGNESIVAKTTVTVPNDGGPIEAVSTIETVP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EKRRSTSRQFVDGPPGPVKKTRSIGSAVDQGNESIVAKTTVTVPNDGGPIEAVSTIETVP
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KA1 YWTRSRRKTGTLQPWNSDSTLNSRQLEPRTETDSVGTPQSNGGMRLHDFVSKTVIKPESC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YWTRSRRKTGTLQPWNSDSTLNSRQLEPRTETDSVGTPQSNGGMRLHDFVSKTVIKPESC
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KA1 VPCGKRIKFGKLSLKCRDCRVVSHPECRDRCPLPCIPTLIGTPVKIGEGMLADFVSQTSP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VPCGKRIKFGKLSLKCRDCRVVSHPECRDRCPLPCIPTLIGTPVKIGEGMLADFVSQTSP
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KA1 MIPSIVVHCVNEIEQRGLTETGLYRISGCDRTVKELKEKFLRVKTVPLLSKVDDIHAICS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MIPSIVVHCVNEIEQRGLTETGLYRISGCDRTVKELKEKFLRVKTVPLLSKVDDIHAICS
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KA1 LLKDFLRNLKEPLLTFRLNRAFMEAAEITDEDNSIAAMYQAVGELPQANRDTLAFLMIHL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LLKDFLRNLKEPLLTFRLNRAFMEAAEITDEDNSIAAMYQAVGELPQANRDTLAFLMIHL
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KA1 QRVAQSPHTKMDVANLAKVFGPTIVAHAVPNPDPVTMLQDIKRQPKVVERLLSLPLEYWS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QRVAQSPHTKMDVANLAKVFGPTIVAHAVPNPDPVTMLQDIKRQPKVVERLLSLPLEYWS
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KA1 QFMMVEQENIDPLHVIENSNAFSTPQTPDIKVSLLGPVTTPEHQLLKTPSSSSLSQRVRS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QFMMVEQENIDPLHVIENSNAFSTPQTPDIKVSLLGPVTTPEHQLLKTPSSSSLSQRVRS
              550       560       570       580       590       600

              610       620       630  
pF1KA1 TLTKNTPRFGSKSKSATNLGRQGNFFASPMLK
       ::::::::::::::::::::::::::::::::
NP_001 TLTKNTPRFGSKSKSATNLGRQGNFFASPMLK
              610       620       630  

>>NP_001306932 (OMIM: 604980) rac GTPase-activating prot  (632 aa)
 initn: 4147 init1: 4147 opt: 4147  Z-score: 3590.8  bits: 674.6 E(85289): 2.9e-193
Smith-Waterman score: 4147; 100.0% identity (100.0% similar) in 632 aa overlap (1-632:1-632)

               10        20        30        40        50        60
pF1KA1 MDTMMLNVRNLFEQLVRRVEILSEGNEVQFIQLAKDFEDFRKKWQRTDHELGKYKDLLMK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MDTMMLNVRNLFEQLVRRVEILSEGNEVQFIQLAKDFEDFRKKWQRTDHELGKYKDLLMK
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KA1 AETERSALDVKLKHARNQVDVEIKRRQRAEADCEKLERQIQLIREMLMCDTSGSIQLSEE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AETERSALDVKLKHARNQVDVEIKRRQRAEADCEKLERQIQLIREMLMCDTSGSIQLSEE
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KA1 QKSALAFLNRGQPSSSNAGNKRLSTIDESGSILSDISFDKTDESLDWDSSLVKTFKLKKR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QKSALAFLNRGQPSSSNAGNKRLSTIDESGSILSDISFDKTDESLDWDSSLVKTFKLKKR
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KA1 EKRRSTSRQFVDGPPGPVKKTRSIGSAVDQGNESIVAKTTVTVPNDGGPIEAVSTIETVP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EKRRSTSRQFVDGPPGPVKKTRSIGSAVDQGNESIVAKTTVTVPNDGGPIEAVSTIETVP
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KA1 YWTRSRRKTGTLQPWNSDSTLNSRQLEPRTETDSVGTPQSNGGMRLHDFVSKTVIKPESC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YWTRSRRKTGTLQPWNSDSTLNSRQLEPRTETDSVGTPQSNGGMRLHDFVSKTVIKPESC
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KA1 VPCGKRIKFGKLSLKCRDCRVVSHPECRDRCPLPCIPTLIGTPVKIGEGMLADFVSQTSP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VPCGKRIKFGKLSLKCRDCRVVSHPECRDRCPLPCIPTLIGTPVKIGEGMLADFVSQTSP
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KA1 MIPSIVVHCVNEIEQRGLTETGLYRISGCDRTVKELKEKFLRVKTVPLLSKVDDIHAICS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MIPSIVVHCVNEIEQRGLTETGLYRISGCDRTVKELKEKFLRVKTVPLLSKVDDIHAICS
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KA1 LLKDFLRNLKEPLLTFRLNRAFMEAAEITDEDNSIAAMYQAVGELPQANRDTLAFLMIHL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LLKDFLRNLKEPLLTFRLNRAFMEAAEITDEDNSIAAMYQAVGELPQANRDTLAFLMIHL
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KA1 QRVAQSPHTKMDVANLAKVFGPTIVAHAVPNPDPVTMLQDIKRQPKVVERLLSLPLEYWS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QRVAQSPHTKMDVANLAKVFGPTIVAHAVPNPDPVTMLQDIKRQPKVVERLLSLPLEYWS
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KA1 QFMMVEQENIDPLHVIENSNAFSTPQTPDIKVSLLGPVTTPEHQLLKTPSSSSLSQRVRS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QFMMVEQENIDPLHVIENSNAFSTPQTPDIKVSLLGPVTTPEHQLLKTPSSSSLSQRVRS
              550       560       570       580       590       600

              610       620       630  
pF1KA1 TLTKNTPRFGSKSKSATNLGRQGNFFASPMLK
       ::::::::::::::::::::::::::::::::
NP_001 TLTKNTPRFGSKSKSATNLGRQGNFFASPMLK
              610       620       630  

>>XP_011536540 (OMIM: 604980) PREDICTED: rac GTPase-acti  (632 aa)
 initn: 4147 init1: 4147 opt: 4147  Z-score: 3590.8  bits: 674.6 E(85289): 2.9e-193
Smith-Waterman score: 4147; 100.0% identity (100.0% similar) in 632 aa overlap (1-632:1-632)

               10        20        30        40        50        60
pF1KA1 MDTMMLNVRNLFEQLVRRVEILSEGNEVQFIQLAKDFEDFRKKWQRTDHELGKYKDLLMK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MDTMMLNVRNLFEQLVRRVEILSEGNEVQFIQLAKDFEDFRKKWQRTDHELGKYKDLLMK
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KA1 AETERSALDVKLKHARNQVDVEIKRRQRAEADCEKLERQIQLIREMLMCDTSGSIQLSEE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AETERSALDVKLKHARNQVDVEIKRRQRAEADCEKLERQIQLIREMLMCDTSGSIQLSEE
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KA1 QKSALAFLNRGQPSSSNAGNKRLSTIDESGSILSDISFDKTDESLDWDSSLVKTFKLKKR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QKSALAFLNRGQPSSSNAGNKRLSTIDESGSILSDISFDKTDESLDWDSSLVKTFKLKKR
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KA1 EKRRSTSRQFVDGPPGPVKKTRSIGSAVDQGNESIVAKTTVTVPNDGGPIEAVSTIETVP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EKRRSTSRQFVDGPPGPVKKTRSIGSAVDQGNESIVAKTTVTVPNDGGPIEAVSTIETVP
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KA1 YWTRSRRKTGTLQPWNSDSTLNSRQLEPRTETDSVGTPQSNGGMRLHDFVSKTVIKPESC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YWTRSRRKTGTLQPWNSDSTLNSRQLEPRTETDSVGTPQSNGGMRLHDFVSKTVIKPESC
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KA1 VPCGKRIKFGKLSLKCRDCRVVSHPECRDRCPLPCIPTLIGTPVKIGEGMLADFVSQTSP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VPCGKRIKFGKLSLKCRDCRVVSHPECRDRCPLPCIPTLIGTPVKIGEGMLADFVSQTSP
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KA1 MIPSIVVHCVNEIEQRGLTETGLYRISGCDRTVKELKEKFLRVKTVPLLSKVDDIHAICS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MIPSIVVHCVNEIEQRGLTETGLYRISGCDRTVKELKEKFLRVKTVPLLSKVDDIHAICS
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KA1 LLKDFLRNLKEPLLTFRLNRAFMEAAEITDEDNSIAAMYQAVGELPQANRDTLAFLMIHL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LLKDFLRNLKEPLLTFRLNRAFMEAAEITDEDNSIAAMYQAVGELPQANRDTLAFLMIHL
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KA1 QRVAQSPHTKMDVANLAKVFGPTIVAHAVPNPDPVTMLQDIKRQPKVVERLLSLPLEYWS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QRVAQSPHTKMDVANLAKVFGPTIVAHAVPNPDPVTMLQDIKRQPKVVERLLSLPLEYWS
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KA1 QFMMVEQENIDPLHVIENSNAFSTPQTPDIKVSLLGPVTTPEHQLLKTPSSSSLSQRVRS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QFMMVEQENIDPLHVIENSNAFSTPQTPDIKVSLLGPVTTPEHQLLKTPSSSSLSQRVRS
              550       560       570       580       590       600

              610       620       630  
pF1KA1 TLTKNTPRFGSKSKSATNLGRQGNFFASPMLK
       ::::::::::::::::::::::::::::::::
XP_011 TLTKNTPRFGSKSKSATNLGRQGNFFASPMLK
              610       620       630  

>>XP_006719422 (OMIM: 604980) PREDICTED: rac GTPase-acti  (632 aa)
 initn: 4147 init1: 4147 opt: 4147  Z-score: 3590.8  bits: 674.6 E(85289): 2.9e-193
Smith-Waterman score: 4147; 100.0% identity (100.0% similar) in 632 aa overlap (1-632:1-632)

               10        20        30        40        50        60
pF1KA1 MDTMMLNVRNLFEQLVRRVEILSEGNEVQFIQLAKDFEDFRKKWQRTDHELGKYKDLLMK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 MDTMMLNVRNLFEQLVRRVEILSEGNEVQFIQLAKDFEDFRKKWQRTDHELGKYKDLLMK
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KA1 AETERSALDVKLKHARNQVDVEIKRRQRAEADCEKLERQIQLIREMLMCDTSGSIQLSEE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 AETERSALDVKLKHARNQVDVEIKRRQRAEADCEKLERQIQLIREMLMCDTSGSIQLSEE
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KA1 QKSALAFLNRGQPSSSNAGNKRLSTIDESGSILSDISFDKTDESLDWDSSLVKTFKLKKR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 QKSALAFLNRGQPSSSNAGNKRLSTIDESGSILSDISFDKTDESLDWDSSLVKTFKLKKR
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KA1 EKRRSTSRQFVDGPPGPVKKTRSIGSAVDQGNESIVAKTTVTVPNDGGPIEAVSTIETVP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 EKRRSTSRQFVDGPPGPVKKTRSIGSAVDQGNESIVAKTTVTVPNDGGPIEAVSTIETVP
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KA1 YWTRSRRKTGTLQPWNSDSTLNSRQLEPRTETDSVGTPQSNGGMRLHDFVSKTVIKPESC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 YWTRSRRKTGTLQPWNSDSTLNSRQLEPRTETDSVGTPQSNGGMRLHDFVSKTVIKPESC
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KA1 VPCGKRIKFGKLSLKCRDCRVVSHPECRDRCPLPCIPTLIGTPVKIGEGMLADFVSQTSP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 VPCGKRIKFGKLSLKCRDCRVVSHPECRDRCPLPCIPTLIGTPVKIGEGMLADFVSQTSP
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KA1 MIPSIVVHCVNEIEQRGLTETGLYRISGCDRTVKELKEKFLRVKTVPLLSKVDDIHAICS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 MIPSIVVHCVNEIEQRGLTETGLYRISGCDRTVKELKEKFLRVKTVPLLSKVDDIHAICS
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KA1 LLKDFLRNLKEPLLTFRLNRAFMEAAEITDEDNSIAAMYQAVGELPQANRDTLAFLMIHL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LLKDFLRNLKEPLLTFRLNRAFMEAAEITDEDNSIAAMYQAVGELPQANRDTLAFLMIHL
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KA1 QRVAQSPHTKMDVANLAKVFGPTIVAHAVPNPDPVTMLQDIKRQPKVVERLLSLPLEYWS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 QRVAQSPHTKMDVANLAKVFGPTIVAHAVPNPDPVTMLQDIKRQPKVVERLLSLPLEYWS
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KA1 QFMMVEQENIDPLHVIENSNAFSTPQTPDIKVSLLGPVTTPEHQLLKTPSSSSLSQRVRS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 QFMMVEQENIDPLHVIENSNAFSTPQTPDIKVSLLGPVTTPEHQLLKTPSSSSLSQRVRS
              550       560       570       580       590       600

              610       620       630  
pF1KA1 TLTKNTPRFGSKSKSATNLGRQGNFFASPMLK
       ::::::::::::::::::::::::::::::::
XP_006 TLTKNTPRFGSKSKSATNLGRQGNFFASPMLK
              610       620       630  

>>NP_001306930 (OMIM: 604980) rac GTPase-activating prot  (632 aa)
 initn: 4147 init1: 4147 opt: 4147  Z-score: 3590.8  bits: 674.6 E(85289): 2.9e-193
Smith-Waterman score: 4147; 100.0% identity (100.0% similar) in 632 aa overlap (1-632:1-632)

               10        20        30        40        50        60
pF1KA1 MDTMMLNVRNLFEQLVRRVEILSEGNEVQFIQLAKDFEDFRKKWQRTDHELGKYKDLLMK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MDTMMLNVRNLFEQLVRRVEILSEGNEVQFIQLAKDFEDFRKKWQRTDHELGKYKDLLMK
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KA1 AETERSALDVKLKHARNQVDVEIKRRQRAEADCEKLERQIQLIREMLMCDTSGSIQLSEE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AETERSALDVKLKHARNQVDVEIKRRQRAEADCEKLERQIQLIREMLMCDTSGSIQLSEE
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KA1 QKSALAFLNRGQPSSSNAGNKRLSTIDESGSILSDISFDKTDESLDWDSSLVKTFKLKKR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QKSALAFLNRGQPSSSNAGNKRLSTIDESGSILSDISFDKTDESLDWDSSLVKTFKLKKR
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KA1 EKRRSTSRQFVDGPPGPVKKTRSIGSAVDQGNESIVAKTTVTVPNDGGPIEAVSTIETVP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EKRRSTSRQFVDGPPGPVKKTRSIGSAVDQGNESIVAKTTVTVPNDGGPIEAVSTIETVP
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KA1 YWTRSRRKTGTLQPWNSDSTLNSRQLEPRTETDSVGTPQSNGGMRLHDFVSKTVIKPESC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YWTRSRRKTGTLQPWNSDSTLNSRQLEPRTETDSVGTPQSNGGMRLHDFVSKTVIKPESC
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KA1 VPCGKRIKFGKLSLKCRDCRVVSHPECRDRCPLPCIPTLIGTPVKIGEGMLADFVSQTSP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VPCGKRIKFGKLSLKCRDCRVVSHPECRDRCPLPCIPTLIGTPVKIGEGMLADFVSQTSP
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KA1 MIPSIVVHCVNEIEQRGLTETGLYRISGCDRTVKELKEKFLRVKTVPLLSKVDDIHAICS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MIPSIVVHCVNEIEQRGLTETGLYRISGCDRTVKELKEKFLRVKTVPLLSKVDDIHAICS
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KA1 LLKDFLRNLKEPLLTFRLNRAFMEAAEITDEDNSIAAMYQAVGELPQANRDTLAFLMIHL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LLKDFLRNLKEPLLTFRLNRAFMEAAEITDEDNSIAAMYQAVGELPQANRDTLAFLMIHL
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KA1 QRVAQSPHTKMDVANLAKVFGPTIVAHAVPNPDPVTMLQDIKRQPKVVERLLSLPLEYWS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QRVAQSPHTKMDVANLAKVFGPTIVAHAVPNPDPVTMLQDIKRQPKVVERLLSLPLEYWS
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KA1 QFMMVEQENIDPLHVIENSNAFSTPQTPDIKVSLLGPVTTPEHQLLKTPSSSSLSQRVRS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QFMMVEQENIDPLHVIENSNAFSTPQTPDIKVSLLGPVTTPEHQLLKTPSSSSLSQRVRS
              550       560       570       580       590       600

              610       620       630  
pF1KA1 TLTKNTPRFGSKSKSATNLGRQGNFFASPMLK
       ::::::::::::::::::::::::::::::::
NP_001 TLTKNTPRFGSKSKSATNLGRQGNFFASPMLK
              610       620       630  

>>NP_037409 (OMIM: 604980) rac GTPase-activating protein  (632 aa)
 initn: 4147 init1: 4147 opt: 4147  Z-score: 3590.8  bits: 674.6 E(85289): 2.9e-193
Smith-Waterman score: 4147; 100.0% identity (100.0% similar) in 632 aa overlap (1-632:1-632)

               10        20        30        40        50        60
pF1KA1 MDTMMLNVRNLFEQLVRRVEILSEGNEVQFIQLAKDFEDFRKKWQRTDHELGKYKDLLMK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_037 MDTMMLNVRNLFEQLVRRVEILSEGNEVQFIQLAKDFEDFRKKWQRTDHELGKYKDLLMK
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KA1 AETERSALDVKLKHARNQVDVEIKRRQRAEADCEKLERQIQLIREMLMCDTSGSIQLSEE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_037 AETERSALDVKLKHARNQVDVEIKRRQRAEADCEKLERQIQLIREMLMCDTSGSIQLSEE
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KA1 QKSALAFLNRGQPSSSNAGNKRLSTIDESGSILSDISFDKTDESLDWDSSLVKTFKLKKR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_037 QKSALAFLNRGQPSSSNAGNKRLSTIDESGSILSDISFDKTDESLDWDSSLVKTFKLKKR
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KA1 EKRRSTSRQFVDGPPGPVKKTRSIGSAVDQGNESIVAKTTVTVPNDGGPIEAVSTIETVP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_037 EKRRSTSRQFVDGPPGPVKKTRSIGSAVDQGNESIVAKTTVTVPNDGGPIEAVSTIETVP
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KA1 YWTRSRRKTGTLQPWNSDSTLNSRQLEPRTETDSVGTPQSNGGMRLHDFVSKTVIKPESC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_037 YWTRSRRKTGTLQPWNSDSTLNSRQLEPRTETDSVGTPQSNGGMRLHDFVSKTVIKPESC
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KA1 VPCGKRIKFGKLSLKCRDCRVVSHPECRDRCPLPCIPTLIGTPVKIGEGMLADFVSQTSP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_037 VPCGKRIKFGKLSLKCRDCRVVSHPECRDRCPLPCIPTLIGTPVKIGEGMLADFVSQTSP
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KA1 MIPSIVVHCVNEIEQRGLTETGLYRISGCDRTVKELKEKFLRVKTVPLLSKVDDIHAICS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_037 MIPSIVVHCVNEIEQRGLTETGLYRISGCDRTVKELKEKFLRVKTVPLLSKVDDIHAICS
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KA1 LLKDFLRNLKEPLLTFRLNRAFMEAAEITDEDNSIAAMYQAVGELPQANRDTLAFLMIHL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_037 LLKDFLRNLKEPLLTFRLNRAFMEAAEITDEDNSIAAMYQAVGELPQANRDTLAFLMIHL
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KA1 QRVAQSPHTKMDVANLAKVFGPTIVAHAVPNPDPVTMLQDIKRQPKVVERLLSLPLEYWS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_037 QRVAQSPHTKMDVANLAKVFGPTIVAHAVPNPDPVTMLQDIKRQPKVVERLLSLPLEYWS
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KA1 QFMMVEQENIDPLHVIENSNAFSTPQTPDIKVSLLGPVTTPEHQLLKTPSSSSLSQRVRS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_037 QFMMVEQENIDPLHVIENSNAFSTPQTPDIKVSLLGPVTTPEHQLLKTPSSSSLSQRVRS
              550       560       570       580       590       600

              610       620       630  
pF1KA1 TLTKNTPRFGSKSKSATNLGRQGNFFASPMLK
       ::::::::::::::::::::::::::::::::
NP_037 TLTKNTPRFGSKSKSATNLGRQGNFFASPMLK
              610       620       630  

>>NP_001119575 (OMIM: 604980) rac GTPase-activating prot  (632 aa)
 initn: 4147 init1: 4147 opt: 4147  Z-score: 3590.8  bits: 674.6 E(85289): 2.9e-193
Smith-Waterman score: 4147; 100.0% identity (100.0% similar) in 632 aa overlap (1-632:1-632)

               10        20        30        40        50        60
pF1KA1 MDTMMLNVRNLFEQLVRRVEILSEGNEVQFIQLAKDFEDFRKKWQRTDHELGKYKDLLMK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MDTMMLNVRNLFEQLVRRVEILSEGNEVQFIQLAKDFEDFRKKWQRTDHELGKYKDLLMK
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KA1 AETERSALDVKLKHARNQVDVEIKRRQRAEADCEKLERQIQLIREMLMCDTSGSIQLSEE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AETERSALDVKLKHARNQVDVEIKRRQRAEADCEKLERQIQLIREMLMCDTSGSIQLSEE
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KA1 QKSALAFLNRGQPSSSNAGNKRLSTIDESGSILSDISFDKTDESLDWDSSLVKTFKLKKR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QKSALAFLNRGQPSSSNAGNKRLSTIDESGSILSDISFDKTDESLDWDSSLVKTFKLKKR
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KA1 EKRRSTSRQFVDGPPGPVKKTRSIGSAVDQGNESIVAKTTVTVPNDGGPIEAVSTIETVP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EKRRSTSRQFVDGPPGPVKKTRSIGSAVDQGNESIVAKTTVTVPNDGGPIEAVSTIETVP
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KA1 YWTRSRRKTGTLQPWNSDSTLNSRQLEPRTETDSVGTPQSNGGMRLHDFVSKTVIKPESC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YWTRSRRKTGTLQPWNSDSTLNSRQLEPRTETDSVGTPQSNGGMRLHDFVSKTVIKPESC
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KA1 VPCGKRIKFGKLSLKCRDCRVVSHPECRDRCPLPCIPTLIGTPVKIGEGMLADFVSQTSP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VPCGKRIKFGKLSLKCRDCRVVSHPECRDRCPLPCIPTLIGTPVKIGEGMLADFVSQTSP
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KA1 MIPSIVVHCVNEIEQRGLTETGLYRISGCDRTVKELKEKFLRVKTVPLLSKVDDIHAICS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MIPSIVVHCVNEIEQRGLTETGLYRISGCDRTVKELKEKFLRVKTVPLLSKVDDIHAICS
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KA1 LLKDFLRNLKEPLLTFRLNRAFMEAAEITDEDNSIAAMYQAVGELPQANRDTLAFLMIHL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LLKDFLRNLKEPLLTFRLNRAFMEAAEITDEDNSIAAMYQAVGELPQANRDTLAFLMIHL
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KA1 QRVAQSPHTKMDVANLAKVFGPTIVAHAVPNPDPVTMLQDIKRQPKVVERLLSLPLEYWS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QRVAQSPHTKMDVANLAKVFGPTIVAHAVPNPDPVTMLQDIKRQPKVVERLLSLPLEYWS
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KA1 QFMMVEQENIDPLHVIENSNAFSTPQTPDIKVSLLGPVTTPEHQLLKTPSSSSLSQRVRS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QFMMVEQENIDPLHVIENSNAFSTPQTPDIKVSLLGPVTTPEHQLLKTPSSSSLSQRVRS
              550       560       570       580       590       600

              610       620       630  
pF1KA1 TLTKNTPRFGSKSKSATNLGRQGNFFASPMLK
       ::::::::::::::::::::::::::::::::
NP_001 TLTKNTPRFGSKSKSATNLGRQGNFFASPMLK
              610       620       630  

>>NP_001306928 (OMIM: 604980) rac GTPase-activating prot  (632 aa)
 initn: 4147 init1: 4147 opt: 4147  Z-score: 3590.8  bits: 674.6 E(85289): 2.9e-193
Smith-Waterman score: 4147; 100.0% identity (100.0% similar) in 632 aa overlap (1-632:1-632)

               10        20        30        40        50        60
pF1KA1 MDTMMLNVRNLFEQLVRRVEILSEGNEVQFIQLAKDFEDFRKKWQRTDHELGKYKDLLMK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MDTMMLNVRNLFEQLVRRVEILSEGNEVQFIQLAKDFEDFRKKWQRTDHELGKYKDLLMK
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KA1 AETERSALDVKLKHARNQVDVEIKRRQRAEADCEKLERQIQLIREMLMCDTSGSIQLSEE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AETERSALDVKLKHARNQVDVEIKRRQRAEADCEKLERQIQLIREMLMCDTSGSIQLSEE
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KA1 QKSALAFLNRGQPSSSNAGNKRLSTIDESGSILSDISFDKTDESLDWDSSLVKTFKLKKR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QKSALAFLNRGQPSSSNAGNKRLSTIDESGSILSDISFDKTDESLDWDSSLVKTFKLKKR
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KA1 EKRRSTSRQFVDGPPGPVKKTRSIGSAVDQGNESIVAKTTVTVPNDGGPIEAVSTIETVP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EKRRSTSRQFVDGPPGPVKKTRSIGSAVDQGNESIVAKTTVTVPNDGGPIEAVSTIETVP
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KA1 YWTRSRRKTGTLQPWNSDSTLNSRQLEPRTETDSVGTPQSNGGMRLHDFVSKTVIKPESC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YWTRSRRKTGTLQPWNSDSTLNSRQLEPRTETDSVGTPQSNGGMRLHDFVSKTVIKPESC
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KA1 VPCGKRIKFGKLSLKCRDCRVVSHPECRDRCPLPCIPTLIGTPVKIGEGMLADFVSQTSP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VPCGKRIKFGKLSLKCRDCRVVSHPECRDRCPLPCIPTLIGTPVKIGEGMLADFVSQTSP
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KA1 MIPSIVVHCVNEIEQRGLTETGLYRISGCDRTVKELKEKFLRVKTVPLLSKVDDIHAICS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MIPSIVVHCVNEIEQRGLTETGLYRISGCDRTVKELKEKFLRVKTVPLLSKVDDIHAICS
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KA1 LLKDFLRNLKEPLLTFRLNRAFMEAAEITDEDNSIAAMYQAVGELPQANRDTLAFLMIHL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LLKDFLRNLKEPLLTFRLNRAFMEAAEITDEDNSIAAMYQAVGELPQANRDTLAFLMIHL
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KA1 QRVAQSPHTKMDVANLAKVFGPTIVAHAVPNPDPVTMLQDIKRQPKVVERLLSLPLEYWS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QRVAQSPHTKMDVANLAKVFGPTIVAHAVPNPDPVTMLQDIKRQPKVVERLLSLPLEYWS
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KA1 QFMMVEQENIDPLHVIENSNAFSTPQTPDIKVSLLGPVTTPEHQLLKTPSSSSLSQRVRS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QFMMVEQENIDPLHVIENSNAFSTPQTPDIKVSLLGPVTTPEHQLLKTPSSSSLSQRVRS
              550       560       570       580       590       600

              610       620       630  
pF1KA1 TLTKNTPRFGSKSKSATNLGRQGNFFASPMLK
       ::::::::::::::::::::::::::::::::
NP_001 TLTKNTPRFGSKSKSATNLGRQGNFFASPMLK
              610       620       630  

>>XP_016874709 (OMIM: 604980) PREDICTED: rac GTPase-acti  (632 aa)
 initn: 4147 init1: 4147 opt: 4147  Z-score: 3590.8  bits: 674.6 E(85289): 2.9e-193
Smith-Waterman score: 4147; 100.0% identity (100.0% similar) in 632 aa overlap (1-632:1-632)

               10        20        30        40        50        60
pF1KA1 MDTMMLNVRNLFEQLVRRVEILSEGNEVQFIQLAKDFEDFRKKWQRTDHELGKYKDLLMK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MDTMMLNVRNLFEQLVRRVEILSEGNEVQFIQLAKDFEDFRKKWQRTDHELGKYKDLLMK
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KA1 AETERSALDVKLKHARNQVDVEIKRRQRAEADCEKLERQIQLIREMLMCDTSGSIQLSEE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AETERSALDVKLKHARNQVDVEIKRRQRAEADCEKLERQIQLIREMLMCDTSGSIQLSEE
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KA1 QKSALAFLNRGQPSSSNAGNKRLSTIDESGSILSDISFDKTDESLDWDSSLVKTFKLKKR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QKSALAFLNRGQPSSSNAGNKRLSTIDESGSILSDISFDKTDESLDWDSSLVKTFKLKKR
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KA1 EKRRSTSRQFVDGPPGPVKKTRSIGSAVDQGNESIVAKTTVTVPNDGGPIEAVSTIETVP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EKRRSTSRQFVDGPPGPVKKTRSIGSAVDQGNESIVAKTTVTVPNDGGPIEAVSTIETVP
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KA1 YWTRSRRKTGTLQPWNSDSTLNSRQLEPRTETDSVGTPQSNGGMRLHDFVSKTVIKPESC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YWTRSRRKTGTLQPWNSDSTLNSRQLEPRTETDSVGTPQSNGGMRLHDFVSKTVIKPESC
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KA1 VPCGKRIKFGKLSLKCRDCRVVSHPECRDRCPLPCIPTLIGTPVKIGEGMLADFVSQTSP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VPCGKRIKFGKLSLKCRDCRVVSHPECRDRCPLPCIPTLIGTPVKIGEGMLADFVSQTSP
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KA1 MIPSIVVHCVNEIEQRGLTETGLYRISGCDRTVKELKEKFLRVKTVPLLSKVDDIHAICS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MIPSIVVHCVNEIEQRGLTETGLYRISGCDRTVKELKEKFLRVKTVPLLSKVDDIHAICS
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KA1 LLKDFLRNLKEPLLTFRLNRAFMEAAEITDEDNSIAAMYQAVGELPQANRDTLAFLMIHL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LLKDFLRNLKEPLLTFRLNRAFMEAAEITDEDNSIAAMYQAVGELPQANRDTLAFLMIHL
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KA1 QRVAQSPHTKMDVANLAKVFGPTIVAHAVPNPDPVTMLQDIKRQPKVVERLLSLPLEYWS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QRVAQSPHTKMDVANLAKVFGPTIVAHAVPNPDPVTMLQDIKRQPKVVERLLSLPLEYWS
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KA1 QFMMVEQENIDPLHVIENSNAFSTPQTPDIKVSLLGPVTTPEHQLLKTPSSSSLSQRVRS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QFMMVEQENIDPLHVIENSNAFSTPQTPDIKVSLLGPVTTPEHQLLKTPSSSSLSQRVRS
              550       560       570       580       590       600

              610       620       630  
pF1KA1 TLTKNTPRFGSKSKSATNLGRQGNFFASPMLK
       ::::::::::::::::::::::::::::::::
XP_016 TLTKNTPRFGSKSKSATNLGRQGNFFASPMLK
              610       620       630  

>>NP_001306931 (OMIM: 604980) rac GTPase-activating prot  (632 aa)
 initn: 4147 init1: 4147 opt: 4147  Z-score: 3590.8  bits: 674.6 E(85289): 2.9e-193
Smith-Waterman score: 4147; 100.0% identity (100.0% similar) in 632 aa overlap (1-632:1-632)

               10        20        30        40        50        60
pF1KA1 MDTMMLNVRNLFEQLVRRVEILSEGNEVQFIQLAKDFEDFRKKWQRTDHELGKYKDLLMK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MDTMMLNVRNLFEQLVRRVEILSEGNEVQFIQLAKDFEDFRKKWQRTDHELGKYKDLLMK
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KA1 AETERSALDVKLKHARNQVDVEIKRRQRAEADCEKLERQIQLIREMLMCDTSGSIQLSEE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AETERSALDVKLKHARNQVDVEIKRRQRAEADCEKLERQIQLIREMLMCDTSGSIQLSEE
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KA1 QKSALAFLNRGQPSSSNAGNKRLSTIDESGSILSDISFDKTDESLDWDSSLVKTFKLKKR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QKSALAFLNRGQPSSSNAGNKRLSTIDESGSILSDISFDKTDESLDWDSSLVKTFKLKKR
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KA1 EKRRSTSRQFVDGPPGPVKKTRSIGSAVDQGNESIVAKTTVTVPNDGGPIEAVSTIETVP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EKRRSTSRQFVDGPPGPVKKTRSIGSAVDQGNESIVAKTTVTVPNDGGPIEAVSTIETVP
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KA1 YWTRSRRKTGTLQPWNSDSTLNSRQLEPRTETDSVGTPQSNGGMRLHDFVSKTVIKPESC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YWTRSRRKTGTLQPWNSDSTLNSRQLEPRTETDSVGTPQSNGGMRLHDFVSKTVIKPESC
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KA1 VPCGKRIKFGKLSLKCRDCRVVSHPECRDRCPLPCIPTLIGTPVKIGEGMLADFVSQTSP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VPCGKRIKFGKLSLKCRDCRVVSHPECRDRCPLPCIPTLIGTPVKIGEGMLADFVSQTSP
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KA1 MIPSIVVHCVNEIEQRGLTETGLYRISGCDRTVKELKEKFLRVKTVPLLSKVDDIHAICS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MIPSIVVHCVNEIEQRGLTETGLYRISGCDRTVKELKEKFLRVKTVPLLSKVDDIHAICS
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KA1 LLKDFLRNLKEPLLTFRLNRAFMEAAEITDEDNSIAAMYQAVGELPQANRDTLAFLMIHL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LLKDFLRNLKEPLLTFRLNRAFMEAAEITDEDNSIAAMYQAVGELPQANRDTLAFLMIHL
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KA1 QRVAQSPHTKMDVANLAKVFGPTIVAHAVPNPDPVTMLQDIKRQPKVVERLLSLPLEYWS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QRVAQSPHTKMDVANLAKVFGPTIVAHAVPNPDPVTMLQDIKRQPKVVERLLSLPLEYWS
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KA1 QFMMVEQENIDPLHVIENSNAFSTPQTPDIKVSLLGPVTTPEHQLLKTPSSSSLSQRVRS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QFMMVEQENIDPLHVIENSNAFSTPQTPDIKVSLLGPVTTPEHQLLKTPSSSSLSQRVRS
              550       560       570       580       590       600

              610       620       630  
pF1KA1 TLTKNTPRFGSKSKSATNLGRQGNFFASPMLK
       ::::::::::::::::::::::::::::::::
NP_001 TLTKNTPRFGSKSKSATNLGRQGNFFASPMLK
              610       620       630  




632 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Wed Nov  2 21:16:16 2016 done: Wed Nov  2 21:16:18 2016
 Total Scan time: 11.280 Total Display time:  0.130

Function used was FASTA [36.3.4 Apr, 2011]
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