Result of FASTA (omim) for pF1KA0850
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KA0850, 642 aa
  1>>>pF1KA0850 642 - 642 aa - 642 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 5.7913+/-0.000409; mu= 17.0192+/- 0.025
 mean_var=98.1520+/-21.521, 0's: 0 Z-trim(111.9): 327  B-trim: 1019 in 1/54
 Lambda= 0.129457
 statistics sampled from 20254 (20670) to 20254 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.601), E-opt: 0.2 (0.242), width:  16
 Scan time:  8.920

The best scores are:                                      opt bits E(85289)
NP_006460 (OMIM: 609209) influenza virus NS1A-bind ( 642) 4391 831.5       0
XP_011507381 (OMIM: 609209) PREDICTED: influenza v ( 649) 4367 827.0       0
XP_011507382 (OMIM: 609209) PREDICTED: influenza v ( 560) 3726 707.2  4e-203
XP_005244900 (OMIM: 609209) PREDICTED: influenza v ( 424) 2930 558.4 1.8e-158
XP_016855573 (OMIM: 609209) PREDICTED: influenza v ( 431) 2906 554.0 4.1e-157
NP_001244124 (OMIM: 605775,614495) kelch-like prot ( 505)  642 131.2   9e-30
NP_001244123 (OMIM: 605775,614495) kelch-like prot ( 555)  642 131.2 9.6e-30
NP_059111 (OMIM: 605775,614495) kelch-like protein ( 587)  642 131.2   1e-29
XP_005260230 (OMIM: 606016) PREDICTED: kelch-like  ( 624)  590 121.5 8.8e-27
XP_005260231 (OMIM: 606016) PREDICTED: kelch-like  ( 624)  590 121.5 8.8e-27
NP_036421 (OMIM: 606016) kelch-like ECH-associated ( 624)  590 121.5 8.8e-27
XP_011526754 (OMIM: 606016) PREDICTED: kelch-like  ( 624)  590 121.5 8.8e-27
NP_987096 (OMIM: 606016) kelch-like ECH-associated ( 624)  590 121.5 8.8e-27
NP_001317952 (OMIM: 605774) kelch-like protein 2 i ( 427)  584 120.3 1.4e-26
NP_067646 (OMIM: 614522) kelch-like protein 12 iso ( 568)  585 120.6 1.6e-26
NP_001317953 (OMIM: 605774) kelch-like protein 2 i ( 496)  584 120.3 1.6e-26
XP_011529878 (OMIM: 605774) PREDICTED: kelch-like  ( 496)  584 120.3 1.6e-26
XP_016863165 (OMIM: 605774) PREDICTED: kelch-like  ( 505)  584 120.3 1.6e-26
NP_001154994 (OMIM: 605774) kelch-like protein 2 i ( 505)  584 120.3 1.6e-26
NP_001289980 (OMIM: 614522) kelch-like protein 12  ( 606)  585 120.6 1.7e-26
XP_011508137 (OMIM: 614522) PREDICTED: kelch-like  ( 623)  585 120.6 1.7e-26
XP_016863163 (OMIM: 605774) PREDICTED: kelch-like  ( 555)  584 120.4 1.8e-26
NP_009177 (OMIM: 605774) kelch-like protein 2 isof ( 593)  584 120.4 1.8e-26
NP_001154993 (OMIM: 605774) kelch-like protein 2 i ( 597)  584 120.4 1.9e-26
XP_011529874 (OMIM: 605774) PREDICTED: kelch-like  ( 633)  584 120.4 1.9e-26
NP_001316525 (OMIM: 608778,615081) kelch-like prot ( 520)  578 119.2 3.6e-26
NP_689680 (OMIM: 608778,615081) kelch-like protein ( 608)  578 119.3 4.1e-26
NP_001316524 (OMIM: 608778,615081) kelch-like prot ( 608)  578 119.3 4.1e-26
NP_001278936 (OMIM: 611967) kelch-like protein 8 i ( 437)  567 117.1 1.3e-25
NP_001278935 (OMIM: 611967) kelch-like protein 8 i ( 544)  567 117.2 1.6e-25
NP_001278932 (OMIM: 611967) kelch-like protein 8 i ( 620)  567 117.2 1.7e-25
NP_065854 (OMIM: 611967) kelch-like protein 8 isof ( 620)  567 117.2 1.7e-25
NP_001026880 (OMIM: 611119,612943,617055) kelch-li ( 586)  511 106.8 2.3e-22
NP_001165125 (OMIM: 608064) kelch-like protein 5 i ( 568)  491 103.0   3e-21
NP_950240 (OMIM: 608064) kelch-like protein 5 isof ( 694)  491 103.1 3.5e-21
NP_001007076 (OMIM: 608064) kelch-like protein 5 i ( 709)  491 103.1 3.6e-21
NP_057074 (OMIM: 608064) kelch-like protein 5 isof ( 755)  491 103.1 3.7e-21
XP_016863765 (OMIM: 608064) PREDICTED: kelch-like  ( 788)  491 103.1 3.9e-21
XP_011512002 (OMIM: 608064) PREDICTED: kelch-like  ( 788)  491 103.1 3.9e-21
XP_011512003 (OMIM: 608064) PREDICTED: kelch-like  ( 788)  491 103.1 3.9e-21
XP_016863764 (OMIM: 608064) PREDICTED: kelch-like  ( 788)  491 103.1 3.9e-21
XP_005262712 (OMIM: 608064) PREDICTED: kelch-like  ( 789)  491 103.1 3.9e-21
XP_011512001 (OMIM: 608064) PREDICTED: kelch-like  ( 804)  491 103.1 3.9e-21
XP_016863763 (OMIM: 608064) PREDICTED: kelch-like  ( 804)  491 103.1 3.9e-21
XP_016863762 (OMIM: 608064) PREDICTED: kelch-like  ( 804)  491 103.1 3.9e-21
XP_016867928 (OMIM: 611119,612943,617055) PREDICTE ( 564)  487 102.3 5.1e-21
XP_005247609 (OMIM: 611295) PREDICTED: kelch-like  ( 600)  464 98.0   1e-19
XP_005247610 (OMIM: 611295) PREDICTED: kelch-like  ( 600)  464 98.0   1e-19
XP_016862148 (OMIM: 611295) PREDICTED: kelch-like  ( 600)  464 98.0   1e-19
XP_005247611 (OMIM: 611295) PREDICTED: kelch-like  ( 600)  464 98.0   1e-19


>>NP_006460 (OMIM: 609209) influenza virus NS1A-binding   (642 aa)
 initn: 4391 init1: 4391 opt: 4391  Z-score: 4438.2  bits: 831.5 E(85289):    0
Smith-Waterman score: 4391; 100.0% identity (100.0% similar) in 642 aa overlap (1-642:1-642)

               10        20        30        40        50        60
pF1KA0 MIPNGYLMFEDENFIESSVAKLNALRKSGQFCDVRLQVCGHEMLAHRAVLACCSPYLFEI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 MIPNGYLMFEDENFIESSVAKLNALRKSGQFCDVRLQVCGHEMLAHRAVLACCSPYLFEI
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KA0 FNSDSDPHGISHVKFDDLNPEAVEVLLNYAYTAQLKADKELVKDVYSAAKKLKMDRVKQV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 FNSDSDPHGISHVKFDDLNPEAVEVLLNYAYTAQLKADKELVKDVYSAAKKLKMDRVKQV
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KA0 CGDYLLSRMDVTSCISYRNFASCMGDSRLLNKVDAYIQEHLLQISEEEEFLKLPRLKLEV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 CGDYLLSRMDVTSCISYRNFASCMGDSRLLNKVDAYIQEHLLQISEEEEFLKLPRLKLEV
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KA0 MLEDNVCLPSNGKLYTKVINWVQRSIWENGDSLEELMEEVQTLYYSADHKLLDGNLLDGQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 MLEDNVCLPSNGKLYTKVINWVQRSIWENGDSLEELMEEVQTLYYSADHKLLDGNLLDGQ
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KA0 AEVFGSDDDHIQFVQKKPPRENGHKQISSSSTGCLSSPNATVQSPKHEWKIVASEKTSNN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 AEVFGSDDDHIQFVQKKPPRENGHKQISSSSTGCLSSPNATVQSPKHEWKIVASEKTSNN
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KA0 TYLCLAVLDGIFCVIFLHGRNSPQSSPTSTPKLSKSLSFEMQQDELIEKPMSPMQYARSG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 TYLCLAVLDGIFCVIFLHGRNSPQSSPTSTPKLSKSLSFEMQQDELIEKPMSPMQYARSG
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KA0 LGTAEMNGKLIAAGGYNREECLRTVECYNPHTDHWSFLAPMRTPRARFQMAVLMGQLYVV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 LGTAEMNGKLIAAGGYNREECLRTVECYNPHTDHWSFLAPMRTPRARFQMAVLMGQLYVV
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KA0 GGSNGHSDDLSCGEMYDSNIDDWIPVPELRTNRCNAGVCALNGKLYIVGGSDPYGQKGLK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 GGSNGHSDDLSCGEMYDSNIDDWIPVPELRTNRCNAGVCALNGKLYIVGGSDPYGQKGLK
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KA0 NCDVFDPVTKLWTSCAPLNIRRHQSAVCELGGYLYIIGGAESWNCLNTVERYNPENNTWT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 NCDVFDPVTKLWTSCAPLNIRRHQSAVCELGGYLYIIGGAESWNCLNTVERYNPENNTWT
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KA0 LIAPMNVARRGAGVAVLNGKLFVCGGFDGSHAISCVEMYDPTRNEWKMMGNMTSPRSNAG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 LIAPMNVARRGAGVAVLNGKLFVCGGFDGSHAISCVEMYDPTRNEWKMMGNMTSPRSNAG
              550       560       570       580       590       600

              610       620       630       640  
pF1KA0 IATVGNTIYAVGGFDGNEFLNTVEVYNLESNEWSPYTKIFQF
       ::::::::::::::::::::::::::::::::::::::::::
NP_006 IATVGNTIYAVGGFDGNEFLNTVEVYNLESNEWSPYTKIFQF
              610       620       630       640  

>>XP_011507381 (OMIM: 609209) PREDICTED: influenza virus  (649 aa)
 initn: 2699 init1: 2699 opt: 4367  Z-score: 4413.9  bits: 827.0 E(85289):    0
Smith-Waterman score: 4367; 98.9% identity (98.9% similar) in 649 aa overlap (1-642:1-649)

               10        20        30        40        50        60
pF1KA0 MIPNGYLMFEDENFIESSVAKLNALRKSGQFCDVRLQVCGHEMLAHRAVLACCSPYLFEI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MIPNGYLMFEDENFIESSVAKLNALRKSGQFCDVRLQVCGHEMLAHRAVLACCSPYLFEI
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KA0 FNSDSDPHGISHVKFDDLNPEAVEVLLNYAYTAQLKADKELVKDVYSAAKKLKMDRVKQV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FNSDSDPHGISHVKFDDLNPEAVEVLLNYAYTAQLKADKELVKDVYSAAKKLKMDRVKQV
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KA0 CGDYLLSRMDVTSCISYRNFASCMGDSRLLNKVDAYIQEHLLQISEEEEFLKLPRLKLEV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CGDYLLSRMDVTSCISYRNFASCMGDSRLLNKVDAYIQEHLLQISEEEEFLKLPRLKLEV
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KA0 MLEDNVCLPSNGKLYTKVINWVQRSIWENGDSLEELMEEVQTLYYSADHKLLDGNLLDGQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MLEDNVCLPSNGKLYTKVINWVQRSIWENGDSLEELMEEVQTLYYSADHKLLDGNLLDGQ
              190       200       210       220       230       240

              250              260       270       280       290   
pF1KA0 AEVFGSDDDHIQFVQ-------KKPPRENGHKQISSSSTGCLSSPNATVQSPKHEWKIVA
       :::::::::::::::       ::::::::::::::::::::::::::::::::::::::
XP_011 AEVFGSDDDHIQFVQVHIAQSEKKPPRENGHKQISSSSTGCLSSPNATVQSPKHEWKIVA
              250       260       270       280       290       300

           300       310       320       330       340       350   
pF1KA0 SEKTSNNTYLCLAVLDGIFCVIFLHGRNSPQSSPTSTPKLSKSLSFEMQQDELIEKPMSP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SEKTSNNTYLCLAVLDGIFCVIFLHGRNSPQSSPTSTPKLSKSLSFEMQQDELIEKPMSP
              310       320       330       340       350       360

           360       370       380       390       400       410   
pF1KA0 MQYARSGLGTAEMNGKLIAAGGYNREECLRTVECYNPHTDHWSFLAPMRTPRARFQMAVL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MQYARSGLGTAEMNGKLIAAGGYNREECLRTVECYNPHTDHWSFLAPMRTPRARFQMAVL
              370       380       390       400       410       420

           420       430       440       450       460       470   
pF1KA0 MGQLYVVGGSNGHSDDLSCGEMYDSNIDDWIPVPELRTNRCNAGVCALNGKLYIVGGSDP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MGQLYVVGGSNGHSDDLSCGEMYDSNIDDWIPVPELRTNRCNAGVCALNGKLYIVGGSDP
              430       440       450       460       470       480

           480       490       500       510       520       530   
pF1KA0 YGQKGLKNCDVFDPVTKLWTSCAPLNIRRHQSAVCELGGYLYIIGGAESWNCLNTVERYN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YGQKGLKNCDVFDPVTKLWTSCAPLNIRRHQSAVCELGGYLYIIGGAESWNCLNTVERYN
              490       500       510       520       530       540

           540       550       560       570       580       590   
pF1KA0 PENNTWTLIAPMNVARRGAGVAVLNGKLFVCGGFDGSHAISCVEMYDPTRNEWKMMGNMT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PENNTWTLIAPMNVARRGAGVAVLNGKLFVCGGFDGSHAISCVEMYDPTRNEWKMMGNMT
              550       560       570       580       590       600

           600       610       620       630       640  
pF1KA0 SPRSNAGIATVGNTIYAVGGFDGNEFLNTVEVYNLESNEWSPYTKIFQF
       :::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SPRSNAGIATVGNTIYAVGGFDGNEFLNTVEVYNLESNEWSPYTKIFQF
              610       620       630       640         

>>XP_011507382 (OMIM: 609209) PREDICTED: influenza virus  (560 aa)
 initn: 2699 init1: 2699 opt: 3726  Z-score: 3767.8  bits: 707.2 E(85289): 4e-203
Smith-Waterman score: 3726; 98.6% identity (98.7% similar) in 556 aa overlap (94-642:5-560)

            70        80        90       100       110       120   
pF1KA0 DSDPHGISHVKFDDLNPEAVEVLLNYAYTAQLKADKELVKDVYSAAKKLKMDRVKQVCGD
                                     .:::::::::::::::::::::::::::::
XP_011                           MFDFRLKADKELVKDVYSAAKKLKMDRVKQVCGD
                                         10        20        30    

           130       140       150       160       170       180   
pF1KA0 YLLSRMDVTSCISYRNFASCMGDSRLLNKVDAYIQEHLLQISEEEEFLKLPRLKLEVMLE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YLLSRMDVTSCISYRNFASCMGDSRLLNKVDAYIQEHLLQISEEEEFLKLPRLKLEVMLE
           40        50        60        70        80        90    

           190       200       210       220       230       240   
pF1KA0 DNVCLPSNGKLYTKVINWVQRSIWENGDSLEELMEEVQTLYYSADHKLLDGNLLDGQAEV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DNVCLPSNGKLYTKVINWVQRSIWENGDSLEELMEEVQTLYYSADHKLLDGNLLDGQAEV
          100       110       120       130       140       150    

           250              260       270       280       290      
pF1KA0 FGSDDDHIQFVQ-------KKPPRENGHKQISSSSTGCLSSPNATVQSPKHEWKIVASEK
       ::::::::::::       :::::::::::::::::::::::::::::::::::::::::
XP_011 FGSDDDHIQFVQVHIAQSEKKPPRENGHKQISSSSTGCLSSPNATVQSPKHEWKIVASEK
          160       170       180       190       200       210    

        300       310       320       330       340       350      
pF1KA0 TSNNTYLCLAVLDGIFCVIFLHGRNSPQSSPTSTPKLSKSLSFEMQQDELIEKPMSPMQY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TSNNTYLCLAVLDGIFCVIFLHGRNSPQSSPTSTPKLSKSLSFEMQQDELIEKPMSPMQY
          220       230       240       250       260       270    

        360       370       380       390       400       410      
pF1KA0 ARSGLGTAEMNGKLIAAGGYNREECLRTVECYNPHTDHWSFLAPMRTPRARFQMAVLMGQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ARSGLGTAEMNGKLIAAGGYNREECLRTVECYNPHTDHWSFLAPMRTPRARFQMAVLMGQ
          280       290       300       310       320       330    

        420       430       440       450       460       470      
pF1KA0 LYVVGGSNGHSDDLSCGEMYDSNIDDWIPVPELRTNRCNAGVCALNGKLYIVGGSDPYGQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LYVVGGSNGHSDDLSCGEMYDSNIDDWIPVPELRTNRCNAGVCALNGKLYIVGGSDPYGQ
          340       350       360       370       380       390    

        480       490       500       510       520       530      
pF1KA0 KGLKNCDVFDPVTKLWTSCAPLNIRRHQSAVCELGGYLYIIGGAESWNCLNTVERYNPEN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KGLKNCDVFDPVTKLWTSCAPLNIRRHQSAVCELGGYLYIIGGAESWNCLNTVERYNPEN
          400       410       420       430       440       450    

        540       550       560       570       580       590      
pF1KA0 NTWTLIAPMNVARRGAGVAVLNGKLFVCGGFDGSHAISCVEMYDPTRNEWKMMGNMTSPR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NTWTLIAPMNVARRGAGVAVLNGKLFVCGGFDGSHAISCVEMYDPTRNEWKMMGNMTSPR
          460       470       480       490       500       510    

        600       610       620       630       640  
pF1KA0 SNAGIATVGNTIYAVGGFDGNEFLNTVEVYNLESNEWSPYTKIFQF
       ::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SNAGIATVGNTIYAVGGFDGNEFLNTVEVYNLESNEWSPYTKIFQF
          520       530       540       550       560

>>XP_005244900 (OMIM: 609209) PREDICTED: influenza virus  (424 aa)
 initn: 2930 init1: 2930 opt: 2930  Z-score: 2966.0  bits: 558.4 E(85289): 1.8e-158
Smith-Waterman score: 2930; 100.0% identity (100.0% similar) in 423 aa overlap (220-642:2-424)

     190       200       210       220       230       240         
pF1KA0 SNGKLYTKVINWVQRSIWENGDSLEELMEEVQTLYYSADHKLLDGNLLDGQAEVFGSDDD
                                     ::::::::::::::::::::::::::::::
XP_005                              MVQTLYYSADHKLLDGNLLDGQAEVFGSDDD
                                            10        20        30 

     250       260       270       280       290       300         
pF1KA0 HIQFVQKKPPRENGHKQISSSSTGCLSSPNATVQSPKHEWKIVASEKTSNNTYLCLAVLD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 HIQFVQKKPPRENGHKQISSSSTGCLSSPNATVQSPKHEWKIVASEKTSNNTYLCLAVLD
              40        50        60        70        80        90 

     310       320       330       340       350       360         
pF1KA0 GIFCVIFLHGRNSPQSSPTSTPKLSKSLSFEMQQDELIEKPMSPMQYARSGLGTAEMNGK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GIFCVIFLHGRNSPQSSPTSTPKLSKSLSFEMQQDELIEKPMSPMQYARSGLGTAEMNGK
             100       110       120       130       140       150 

     370       380       390       400       410       420         
pF1KA0 LIAAGGYNREECLRTVECYNPHTDHWSFLAPMRTPRARFQMAVLMGQLYVVGGSNGHSDD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LIAAGGYNREECLRTVECYNPHTDHWSFLAPMRTPRARFQMAVLMGQLYVVGGSNGHSDD
             160       170       180       190       200       210 

     430       440       450       460       470       480         
pF1KA0 LSCGEMYDSNIDDWIPVPELRTNRCNAGVCALNGKLYIVGGSDPYGQKGLKNCDVFDPVT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LSCGEMYDSNIDDWIPVPELRTNRCNAGVCALNGKLYIVGGSDPYGQKGLKNCDVFDPVT
             220       230       240       250       260       270 

     490       500       510       520       530       540         
pF1KA0 KLWTSCAPLNIRRHQSAVCELGGYLYIIGGAESWNCLNTVERYNPENNTWTLIAPMNVAR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KLWTSCAPLNIRRHQSAVCELGGYLYIIGGAESWNCLNTVERYNPENNTWTLIAPMNVAR
             280       290       300       310       320       330 

     550       560       570       580       590       600         
pF1KA0 RGAGVAVLNGKLFVCGGFDGSHAISCVEMYDPTRNEWKMMGNMTSPRSNAGIATVGNTIY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RGAGVAVLNGKLFVCGGFDGSHAISCVEMYDPTRNEWKMMGNMTSPRSNAGIATVGNTIY
             340       350       360       370       380       390 

     610       620       630       640  
pF1KA0 AVGGFDGNEFLNTVEVYNLESNEWSPYTKIFQF
       :::::::::::::::::::::::::::::::::
XP_005 AVGGFDGNEFLNTVEVYNLESNEWSPYTKIFQF
             400       410       420    

>>XP_016855573 (OMIM: 609209) PREDICTED: influenza virus  (431 aa)
 initn: 2699 init1: 2699 opt: 2906  Z-score: 2941.6  bits: 554.0 E(85289): 4.1e-157
Smith-Waterman score: 2906; 98.4% identity (98.4% similar) in 430 aa overlap (220-642:2-431)

     190       200       210       220       230       240         
pF1KA0 SNGKLYTKVINWVQRSIWENGDSLEELMEEVQTLYYSADHKLLDGNLLDGQAEVFGSDDD
                                     ::::::::::::::::::::::::::::::
XP_016                              MVQTLYYSADHKLLDGNLLDGQAEVFGSDDD
                                            10        20        30 

     250              260       270       280       290       300  
pF1KA0 HIQFVQ-------KKPPRENGHKQISSSSTGCLSSPNATVQSPKHEWKIVASEKTSNNTY
       ::::::       :::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HIQFVQVHIAQSEKKPPRENGHKQISSSSTGCLSSPNATVQSPKHEWKIVASEKTSNNTY
              40        50        60        70        80        90 

            310       320       330       340       350       360  
pF1KA0 LCLAVLDGIFCVIFLHGRNSPQSSPTSTPKLSKSLSFEMQQDELIEKPMSPMQYARSGLG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LCLAVLDGIFCVIFLHGRNSPQSSPTSTPKLSKSLSFEMQQDELIEKPMSPMQYARSGLG
             100       110       120       130       140       150 

            370       380       390       400       410       420  
pF1KA0 TAEMNGKLIAAGGYNREECLRTVECYNPHTDHWSFLAPMRTPRARFQMAVLMGQLYVVGG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TAEMNGKLIAAGGYNREECLRTVECYNPHTDHWSFLAPMRTPRARFQMAVLMGQLYVVGG
             160       170       180       190       200       210 

            430       440       450       460       470       480  
pF1KA0 SNGHSDDLSCGEMYDSNIDDWIPVPELRTNRCNAGVCALNGKLYIVGGSDPYGQKGLKNC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SNGHSDDLSCGEMYDSNIDDWIPVPELRTNRCNAGVCALNGKLYIVGGSDPYGQKGLKNC
             220       230       240       250       260       270 

            490       500       510       520       530       540  
pF1KA0 DVFDPVTKLWTSCAPLNIRRHQSAVCELGGYLYIIGGAESWNCLNTVERYNPENNTWTLI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DVFDPVTKLWTSCAPLNIRRHQSAVCELGGYLYIIGGAESWNCLNTVERYNPENNTWTLI
             280       290       300       310       320       330 

            550       560       570       580       590       600  
pF1KA0 APMNVARRGAGVAVLNGKLFVCGGFDGSHAISCVEMYDPTRNEWKMMGNMTSPRSNAGIA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 APMNVARRGAGVAVLNGKLFVCGGFDGSHAISCVEMYDPTRNEWKMMGNMTSPRSNAGIA
             340       350       360       370       380       390 

            610       620       630       640  
pF1KA0 TVGNTIYAVGGFDGNEFLNTVEVYNLESNEWSPYTKIFQF
       ::::::::::::::::::::::::::::::::::::::::
XP_016 TVGNTIYAVGGFDGNEFLNTVEVYNLESNEWSPYTKIFQF
             400       410       420       430 

>>NP_001244124 (OMIM: 605775,614495) kelch-like protein   (505 aa)
 initn: 383 init1: 383 opt: 642  Z-score: 655.5  bits: 131.2 E(85289): 9e-30
Smith-Waterman score: 750; 28.6% identity (58.6% similar) in 539 aa overlap (73-608:9-505)

             50        60        70        80        90       100  
pF1KA0 MLAHRAVLACCSPYLFEIFNSDSDPHGISHVKFDDLNPEAVEVLLNYAYTAQLKADKELV
                                     ... :.. ...  :..: :::.... .: :
NP_001                       MSESKAKKIEIKDVDGQTLSKLIDYIYTAEIEVTEENV
                                     10        20        30        

            110       120       130       140       150       160  
pF1KA0 KDVYSAAKKLKMDRVKQVCGDYLLSRMDVTSCISYRNFASCMGDSRLLNKVDAYIQEHLL
       . .  ::. :..  :.: : :.: :..  :.:.. : ::.    . ::....:: ..:. 
NP_001 QVLLPAASLLQLMDVRQNCCDFLQSQLHPTNCLGIRAFADVHTCTDLLQQANAYAEQHFP
       40        50        60        70        80        90        

            170       180        190       200       210       220 
pF1KA0 QISEEEEFLKLPRLKLEVMLE-DNVCLPSNGKLYTKVINWVQRSIWENGDSLEELMEEVQ
       ..   ::::.:   ..  ..  :.. . :. :..  ::.:..       . . .:::.:.
NP_001 EVMLGEEFLSLSLDQVCSLISSDKLTVSSEEKVFEAVISWINYEKETRLEHMAKLMEHVR
      100       110       120       130       140       150        

             230       240       250       260       270       280 
pF1KA0 TLYYSADHKLLDGNLLDGQAEVFGSDDDHIQFVQKKPPRENGHKQISSSSTGCLSSPNAT
                ::  . :             .: :...   .:     ...    :      
NP_001 L-------PLLPRDYL-------------VQTVEEEALIKN-----NNTCKDFLIEAMKY
             160                    170            180       190   

             290       300       310       320       330        340
pF1KA0 VQSPKHEWKIVASEKTSNNTYLCLAVLDGIFCVIFLHGRNSPQSSPTSTPKLSKSLS-FE
          :  .  .. . .:.  : . :  .     .: . :.         .::  .:.  ..
NP_001 HLLPLDQRLLIKNPRTKPRTPVSLPKV-----MIVVGGQ---------APKAIRSVECYD
           200       210       220                     230         

              350       360       370       380       390       400
pF1KA0 MQQDELIEKPMSPMQYARSGLGTAEMNGKLIAAGGYNREECLRTVECYNPHTDHWSFLAP
       ...:.  .    : .  :.:.  . : :.. :.::.:    .:::. :.   :.:. .: 
NP_001 FEEDRWDQIAELPSRRCRAGV--VFMAGHVYAVGGFNGSLRVRTVDVYDGVKDQWTSIAS
     240       250       260         270       280       290       

              410       420       430       440       450       460
pF1KA0 MRTPRARFQMAVLMGQLYVVGGSNGHSDDLSCGEMYDSNIDDWIPVPELRTNRCNAGVCA
       :.  :. .  :::   ::.::: .: :  :.  : :. . ..:. :  . : : ..:: .
NP_001 MQERRSTLGAAVLNDLLYAVGGFDG-STGLASVEAYSYKTNEWFFVAPMNTRRSSVGVGV
       300       310       320        330       340       350      

              470       480       490       500       510       520
pF1KA0 LNGKLYIVGGSDPYGQKGLKNCDVFDPVTKLWTSCAPLNIRRHQSAVCELGGYLYIIGGA
       ..:::: ::: :  ... :.. . ..:.:. :   : .. ::  ..:  :.: ::  :: 
NP_001 VEGKLYAVGGYDGASRQCLSTVEQYNPATNEWIYVADMSTRRSGAGVGVLSGQLYATGGH
        360       370       380       390       400       410      

              530       540       550       560       570       580
pF1KA0 ESWNCLNTVERYNPENNTWTLIAPMNVARRGAGVAVLNGKLFVCGGFDGSHAISCVEMYD
       ..    ..:: :.: .:::  .: ::. ::.::: ..:: :.: :: :::  .. ::.:.
NP_001 DGPLVRKSVEVYDPGTNTWKQVADMNMCRRNAGVCAVNGLLYVVGGDDGSCNLASVEYYN
        420       430       440       450       460       470      

              590        600       610       620       630         
pF1KA0 PTRNEWKMMG-NMTSPRSNAGIATVGNTIYAVGGFDGNEFLNTVEVYNLESNEWSPYTKI
       :. ..: ..  ::.. :: ::.:.. ...                               
NP_001 PVTDKWTLLPTNMSTGRSYAGVAVIHKSL                               
        480       490       500                                    

>>NP_001244123 (OMIM: 605775,614495) kelch-like protein   (555 aa)
 initn: 1066 init1: 383 opt: 642  Z-score: 655.0  bits: 131.2 E(85289): 9.6e-30
Smith-Waterman score: 869; 29.3% identity (59.3% similar) in 590 aa overlap (22-608:8-555)

               10        20        30        40        50        60
pF1KA0 MIPNGYLMFEDENFIESSVAKLNALRKSGQFCDVRLQVCGHEMLAHRAVLACCSPYLFEI
                            .: ::..  .::: . .   :. :::.::: ::::.  .
NP_001               MGKAFKVMNELRSKQLLCDVMIVAEDVEIEAHRVVLAACSPYFCAM
                             10        20        30        40      

               70        80        90       100       110       120
pF1KA0 FNSDSDPHGISHVKFDDLNPEAVEVLLNYAYTAQLKADKELVKDVYSAAKKLKMDRVKQV
       :..: .    ..... :.. ...  :..: :::.... .: :. .  ::. :..  :.: 
NP_001 FTGDMSESKAKKIEIKDVDGQTLSKLIDYIYTAEIEVTEENVQVLLPAASLLQLMDVRQN
         50        60        70        80        90       100      

              130       140       150       160       170       180
pF1KA0 CGDYLLSRMDVTSCISYRNFASCMGDSRLLNKVDAYIQEHLLQISEEEEFLKLPRLKLEV
       : :.: :..  :.:.. : ::.    . ::....:: ..:. ..   ::::.:   ..  
NP_001 CCDFLQSQLHPTNCLGIRAFADVHTCTDLLQQANAYAEQHFPEVMLGEEFLSLSLDQVCS
        110       120       130       140       150       160      

               190       200       210       220       230         
pF1KA0 MLE-DNVCLPSNGKLYTKVINWVQRSIWENGDSLEELMEEVQTLYYSADHKLLDGNLLDG
       ..  :.. . :. :..  ::.:..       . . .:::.:.         ::  . :  
NP_001 LISSDKLTVSSEEKVFEAVISWINYEKETRLEHMAKLMEHVRL-------PLLPRDYL--
        170       180       190       200              210         

     240       250       260       270       280       290         
pF1KA0 QAEVFGSDDDHIQFVQKKPPRENGHKQISSSSTGCLSSPNATVQSPKHEWKIVASEKTSN
                  .: :...   .:     ...    :         :  .  .. . .:. 
NP_001 -----------VQTVEEEALIKN-----NNTCKDFLIEAMKYHLLPLDQRLLIKNPRTKP
                  220            230       240       250       260 

     300       310       320       330        340       350        
pF1KA0 NTYLCLAVLDGIFCVIFLHGRNSPQSSPTSTPKLSKSLS-FEMQQDELIEKPMSPMQYAR
        : . :  .     .: . :.         .::  .:.  .....:.  .    : .  :
NP_001 RTPVSLPKV-----MIVVGGQ---------APKAIRSVECYDFEEDRWDQIAELPSRRCR
             270                     280       290       300       

      360       370       380       390       400       410        
pF1KA0 SGLGTAEMNGKLIAAGGYNREECLRTVECYNPHTDHWSFLAPMRTPRARFQMAVLMGQLY
       .:.  . : :.. :.::.:    .:::. :.   :.:. .: :.  :. .  :::   ::
NP_001 AGV--VFMAGHVYAVGGFNGSLRVRTVDVYDGVKDQWTSIASMQERRSTLGAAVLNDLLY
       310         320       330       340       350       360     

      420       430       440       450       460       470        
pF1KA0 VVGGSNGHSDDLSCGEMYDSNIDDWIPVPELRTNRCNAGVCALNGKLYIVGGSDPYGQKG
       .::: .: :  :.  : :. . ..:. :  . : : ..:: ...:::: ::: :  ... 
NP_001 AVGGFDG-STGLASVEAYSYKTNEWFFVAPMNTRRSSVGVGVVEGKLYAVGGYDGASRQC
         370        380       390       400       410       420    

      480       490       500       510       520       530        
pF1KA0 LKNCDVFDPVTKLWTSCAPLNIRRHQSAVCELGGYLYIIGGAESWNCLNTVERYNPENNT
       :.. . ..:.:. :   : .. ::  ..:  :.: ::  :: ..    ..:: :.: .::
NP_001 LSTVEQYNPATNEWIYVADMSTRRSGAGVGVLSGQLYATGGHDGPLVRKSVEVYDPGTNT
          430       440       450       460       470       480    

      540       550       560       570       580       590        
pF1KA0 WTLIAPMNVARRGAGVAVLNGKLFVCGGFDGSHAISCVEMYDPTRNEWKMMG-NMTSPRS
       :  .: ::. ::.::: ..:: :.: :: :::  .. ::.:.:. ..: ..  ::.. ::
NP_001 WKQVADMNMCRRNAGVCAVNGLLYVVGGDDGSCNLASVEYYNPVTDKWTLLPTNMSTGRS
          490       500       510       520       530       540    

       600       610       620       630       640  
pF1KA0 NAGIATVGNTIYAVGGFDGNEFLNTVEVYNLESNEWSPYTKIFQF
        ::.:.. ...                                  
NP_001 YAGVAVIHKSL                                  
          550                                       

>>NP_059111 (OMIM: 605775,614495) kelch-like protein 3 i  (587 aa)
 initn: 909 init1: 383 opt: 642  Z-score: 654.6  bits: 131.2 E(85289): 1e-29
Smith-Waterman score: 869; 29.3% identity (59.3% similar) in 590 aa overlap (22-608:40-587)

                        10        20        30        40        50 
pF1KA0          MIPNGYLMFEDENFIESSVAKLNALRKSGQFCDVRLQVCGHEMLAHRAVLA
                                     .: ::..  .::: . .   :. :::.:::
NP_059 SQTLIQAGDDEKNQRTITVNPAHMGKAFKVMNELRSKQLLCDVMIVAEDVEIEAHRVVLA
      10        20        30        40        50        60         

              60        70        80        90       100       110 
pF1KA0 CCSPYLFEIFNSDSDPHGISHVKFDDLNPEAVEVLLNYAYTAQLKADKELVKDVYSAAKK
        ::::.  .:..: .    ..... :.. ...  :..: :::.... .: :. .  ::. 
NP_059 ACSPYFCAMFTGDMSESKAKKIEIKDVDGQTLSKLIDYIYTAEIEVTEENVQVLLPAASL
      70        80        90       100       110       120         

             120       130       140       150       160       170 
pF1KA0 LKMDRVKQVCGDYLLSRMDVTSCISYRNFASCMGDSRLLNKVDAYIQEHLLQISEEEEFL
       :..  :.: : :.: :..  :.:.. : ::.    . ::....:: ..:. ..   ::::
NP_059 LQLMDVRQNCCDFLQSQLHPTNCLGIRAFADVHTCTDLLQQANAYAEQHFPEVMLGEEFL
     130       140       150       160       170       180         

             180        190       200       210       220       230
pF1KA0 KLPRLKLEVMLE-DNVCLPSNGKLYTKVINWVQRSIWENGDSLEELMEEVQTLYYSADHK
       .:   ..  ..  :.. . :. :..  ::.:..       . . .:::.:.         
NP_059 SLSLDQVCSLISSDKLTVSSEEKVFEAVISWINYEKETRLEHMAKLMEHVRL-------P
     190       200       210       220       230       240         

              240       250       260       270       280       290
pF1KA0 LLDGNLLDGQAEVFGSDDDHIQFVQKKPPRENGHKQISSSSTGCLSSPNATVQSPKHEWK
       ::  . :             .: :...   .:     ...    :         :  .  
NP_059 LLPRDYL-------------VQTVEEEALIKN-----NNTCKDFLIEAMKYHLLPLDQRL
                         250       260            270       280    

              300       310       320       330        340         
pF1KA0 IVASEKTSNNTYLCLAVLDGIFCVIFLHGRNSPQSSPTSTPKLSKSLS-FEMQQDELIEK
       .. . .:.  : . :  .     .: . :.         .::  .:.  .....:.  . 
NP_059 LIKNPRTKPRTPVSLPKV-----MIVVGGQ---------APKAIRSVECYDFEEDRWDQI
          290       300                     310       320       330

     350       360       370       380       390       400         
pF1KA0 PMSPMQYARSGLGTAEMNGKLIAAGGYNREECLRTVECYNPHTDHWSFLAPMRTPRARFQ
          : .  :.:.  . : :.. :.::.:    .:::. :.   :.:. .: :.  :. . 
NP_059 AELPSRRCRAGV--VFMAGHVYAVGGFNGSLRVRTVDVYDGVKDQWTSIASMQERRSTLG
              340         350       360       370       380        

     410       420       430       440       450       460         
pF1KA0 MAVLMGQLYVVGGSNGHSDDLSCGEMYDSNIDDWIPVPELRTNRCNAGVCALNGKLYIVG
        :::   ::.::: .: :  :.  : :. . ..:. :  . : : ..:: ...:::: ::
NP_059 AAVLNDLLYAVGGFDG-STGLASVEAYSYKTNEWFFVAPMNTRRSSVGVGVVEGKLYAVG
      390       400        410       420       430       440       

     470       480       490       500       510       520         
pF1KA0 GSDPYGQKGLKNCDVFDPVTKLWTSCAPLNIRRHQSAVCELGGYLYIIGGAESWNCLNTV
       : :  ... :.. . ..:.:. :   : .. ::  ..:  :.: ::  :: ..    ..:
NP_059 GYDGASRQCLSTVEQYNPATNEWIYVADMSTRRSGAGVGVLSGQLYATGGHDGPLVRKSV
       450       460       470       480       490       500       

     530       540       550       560       570       580         
pF1KA0 ERYNPENNTWTLIAPMNVARRGAGVAVLNGKLFVCGGFDGSHAISCVEMYDPTRNEWKMM
       : :.: .:::  .: ::. ::.::: ..:: :.: :: :::  .. ::.:.:. ..: ..
NP_059 EVYDPGTNTWKQVADMNMCRRNAGVCAVNGLLYVVGGDDGSCNLASVEYYNPVTDKWTLL
       510       520       530       540       550       560       

     590        600       610       620       630       640  
pF1KA0 G-NMTSPRSNAGIATVGNTIYAVGGFDGNEFLNTVEVYNLESNEWSPYTKIFQF
         ::.. :: ::.:.. ...                                  
NP_059 PTNMSTGRSYAGVAVIHKSL                                  
       570       580                                         

>>XP_005260230 (OMIM: 606016) PREDICTED: kelch-like ECH-  (624 aa)
 initn: 1110 init1: 455 opt: 590  Z-score: 601.8  bits: 121.5 E(85289): 8.8e-27
Smith-Waterman score: 769; 28.9% identity (58.2% similar) in 584 aa overlap (12-580:57-585)

                                  10        20        30        40 
pF1KA0                    MIPNGYLMFEDENFIESSVAKLNALRKSGQFCDVRLQVCGH
                                     :.  ... . .: :: : :.::: :::  .
XP_005 AGDAVMYASTECKAEVTPSQHGNRTFSYTLEDHTKQAFGIMNELRLSQQLCDVTLQVKYQ
         30        40        50        60        70        80      

                   50        60        70        80        90      
pF1KA0 E-----MLAHRAVLACCSPYLFEIFNSDSDPHGISHVKFDDLNPEAVEVLLNYAYTAQLK
       .     ..::..:::  :: .  .:..    .:.  :... ..:...: :...::::...
XP_005 DAPAAQFMAHKVVLASSSPVFKAMFTNGLREQGMEVVSIEGIHPKVMERLIEFAYTASIS
         90       100       110       120       130       140      

        100       110       120       130       140       150      
pF1KA0 ADKELVKDVYSAAKKLKMDRVKQVCGDYLLSRMDVTSCISYRNFASCMGDSRLLNKVDAY
         .. :  :...:   ..: : ..:.:.:....: .. :.  :::  .:  .: ...  :
XP_005 MGEKCVLHVMNGAVMYQIDSVVRACSDFLVQQLDPSNAIGIANFAEQIGCVELHQRAREY
        150       160       170       180       190       200      

        160       170       180        190       200       210     
pF1KA0 IQEHLLQISEEEEFLKLPRLKLEVML-EDNVCLPSNGKLYTKVINWVQRSIWENGDSLEE
       :  :. .....:::..: . .: ... .:.. .  .....   ::::. .        :.
XP_005 IYMHFGEVAKQEEFFNLSHCQLVTLISRDDLNVRCESEVFHACINWVKYDC-------EQ
        210       220       230       240       250                

         220       230       240          250       260       270  
pF1KA0 LMEEVQTLYYSADHKLLDGNLLDGQ---AEVFGSDDDHIQFVQKKPPRENGHKQISSSST
           ::.:  ..  . :  :.:. :    :.. ::.   ... :   . . ::   ..  
XP_005 RRFYVQALLRAVRCHSLTPNFLQMQLQKCEILQSDSRCKDYLVKIFEELTLHKP--TQVM
     260       270       280       290       300       310         

            280       290       300       310       320       330  
pF1KA0 GCLSSPNATVQSPKHEWKIVASEKTSNNTYLCLAVLDGIFCVIFLHGRNSPQSSPTSTPK
        :        ..::                        .  .:.  :    ::       
XP_005 PC--------RAPK------------------------VGRLIYTAGGYFRQS-------
               320                               330               

            340       350       360       370       380            
pF1KA0 LSKSLSFEMQQDELIEKPMSPMQYARSGLGTAEMNGKLIAAGGYNREECLRT----VECY
       ::   ... ..   ..  .. .:  ::::.   ..: : :.:: :      :    ..::
XP_005 LSYLEAYNPSDGTWLR--LADLQVPRSGLAGCVVGGLLYAVGGRNNSPDGNTDSSALDCY
      340       350         360       370       380       390      

      390       400       410       420         430       440      
pF1KA0 NPHTDHWSFLAPMRTPRARFQMAVLMGQLYVVGGSNG--HSDDLSCGEMYDSNIDDWIPV
       :: :..::  ::: .:: :. ..:. :..:.::::.:  : ...   : :. . :.:  :
XP_005 NPMTNQWSPCAPMSVPRNRIGVGVIDGHIYAVGGSHGCIHHNSV---ERYEPERDEWHLV
        400       410       420       430       440          450   

        450       460       470       480       490       500      
pF1KA0 PELRTNRCNAGVCALNGKLYIVGGSDPYGQKGLKNCDVFDPVTKLWTSCAPLNIRRHQSA
         . : : ..:: .::  :: ::: :  : . :.. . . :  . :   . .:  :  ..
XP_005 APMLTRRIGVGVAVLNRLLYAVGGFD--GTNRLNSAECYYPERNEWRMITAMNTIRSGAG
           460       470         480       490       500       510 

        510       520       530       540       550       560      
pF1KA0 VCELGGYLYIIGGAESWNCLNTVERYNPENNTWTLIAPMNVARRGAGVAVLNGKLFVCGG
       :: : . .:  :: .. . ::.::::. :..:::..:::.  : . :..: .:...: ::
XP_005 VCVLHNCIYAAGGYDGQDQLNSVERYDVETETWTFVAPMKHRRSALGITVHQGRIYVLGG
             520       530       540       550       560       570 

        570       580       590       600       610       620      
pF1KA0 FDGSHAISCVEMYDPTRNEWKMMGNMTSPRSNAGIATVGNTIYAVGGFDGNEFLNTVEVY
       .::   .. :: ::                                              
XP_005 YDGHTFLDSVECYDPDTDTWSEVTRMTSGRSGVGVAVTMEPCRKQIDQQNCTC       
             580       590       600       610       620           

>>XP_005260231 (OMIM: 606016) PREDICTED: kelch-like ECH-  (624 aa)
 initn: 1110 init1: 455 opt: 590  Z-score: 601.8  bits: 121.5 E(85289): 8.8e-27
Smith-Waterman score: 769; 28.9% identity (58.2% similar) in 584 aa overlap (12-580:57-585)

                                  10        20        30        40 
pF1KA0                    MIPNGYLMFEDENFIESSVAKLNALRKSGQFCDVRLQVCGH
                                     :.  ... . .: :: : :.::: :::  .
XP_005 AGDAVMYASTECKAEVTPSQHGNRTFSYTLEDHTKQAFGIMNELRLSQQLCDVTLQVKYQ
         30        40        50        60        70        80      

                   50        60        70        80        90      
pF1KA0 E-----MLAHRAVLACCSPYLFEIFNSDSDPHGISHVKFDDLNPEAVEVLLNYAYTAQLK
       .     ..::..:::  :: .  .:..    .:.  :... ..:...: :...::::...
XP_005 DAPAAQFMAHKVVLASSSPVFKAMFTNGLREQGMEVVSIEGIHPKVMERLIEFAYTASIS
         90       100       110       120       130       140      

        100       110       120       130       140       150      
pF1KA0 ADKELVKDVYSAAKKLKMDRVKQVCGDYLLSRMDVTSCISYRNFASCMGDSRLLNKVDAY
         .. :  :...:   ..: : ..:.:.:....: .. :.  :::  .:  .: ...  :
XP_005 MGEKCVLHVMNGAVMYQIDSVVRACSDFLVQQLDPSNAIGIANFAEQIGCVELHQRAREY
        150       160       170       180       190       200      

        160       170       180        190       200       210     
pF1KA0 IQEHLLQISEEEEFLKLPRLKLEVML-EDNVCLPSNGKLYTKVINWVQRSIWENGDSLEE
       :  :. .....:::..: . .: ... .:.. .  .....   ::::. .        :.
XP_005 IYMHFGEVAKQEEFFNLSHCQLVTLISRDDLNVRCESEVFHACINWVKYDC-------EQ
        210       220       230       240       250                

         220       230       240          250       260       270  
pF1KA0 LMEEVQTLYYSADHKLLDGNLLDGQ---AEVFGSDDDHIQFVQKKPPRENGHKQISSSST
           ::.:  ..  . :  :.:. :    :.. ::.   ... :   . . ::   ..  
XP_005 RRFYVQALLRAVRCHSLTPNFLQMQLQKCEILQSDSRCKDYLVKIFEELTLHKP--TQVM
     260       270       280       290       300       310         

            280       290       300       310       320       330  
pF1KA0 GCLSSPNATVQSPKHEWKIVASEKTSNNTYLCLAVLDGIFCVIFLHGRNSPQSSPTSTPK
        :        ..::                        .  .:.  :    ::       
XP_005 PC--------RAPK------------------------VGRLIYTAGGYFRQS-------
               320                               330               

            340       350       360       370       380            
pF1KA0 LSKSLSFEMQQDELIEKPMSPMQYARSGLGTAEMNGKLIAAGGYNREECLRT----VECY
       ::   ... ..   ..  .. .:  ::::.   ..: : :.:: :      :    ..::
XP_005 LSYLEAYNPSDGTWLR--LADLQVPRSGLAGCVVGGLLYAVGGRNNSPDGNTDSSALDCY
      340       350         360       370       380       390      

      390       400       410       420         430       440      
pF1KA0 NPHTDHWSFLAPMRTPRARFQMAVLMGQLYVVGGSNG--HSDDLSCGEMYDSNIDDWIPV
       :: :..::  ::: .:: :. ..:. :..:.::::.:  : ...   : :. . :.:  :
XP_005 NPMTNQWSPCAPMSVPRNRIGVGVIDGHIYAVGGSHGCIHHNSV---ERYEPERDEWHLV
        400       410       420       430       440          450   

        450       460       470       480       490       500      
pF1KA0 PELRTNRCNAGVCALNGKLYIVGGSDPYGQKGLKNCDVFDPVTKLWTSCAPLNIRRHQSA
         . : : ..:: .::  :: ::: :  : . :.. . . :  . :   . .:  :  ..
XP_005 APMLTRRIGVGVAVLNRLLYAVGGFD--GTNRLNSAECYYPERNEWRMITAMNTIRSGAG
           460       470         480       490       500       510 

        510       520       530       540       550       560      
pF1KA0 VCELGGYLYIIGGAESWNCLNTVERYNPENNTWTLIAPMNVARRGAGVAVLNGKLFVCGG
       :: : . .:  :: .. . ::.::::. :..:::..:::.  : . :..: .:...: ::
XP_005 VCVLHNCIYAAGGYDGQDQLNSVERYDVETETWTFVAPMKHRRSALGITVHQGRIYVLGG
             520       530       540       550       560       570 

        570       580       590       600       610       620      
pF1KA0 FDGSHAISCVEMYDPTRNEWKMMGNMTSPRSNAGIATVGNTIYAVGGFDGNEFLNTVEVY
       .::   .. :: ::                                              
XP_005 YDGHTFLDSVECYDPDTDTWSEVTRMTSGRSGVGVAVTMEPCRKQIDQQNCTC       
             580       590       600       610       620           




642 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Wed Nov  2 19:50:18 2016 done: Wed Nov  2 19:50:20 2016
 Total Scan time:  8.920 Total Display time:  0.110

Function used was FASTA [36.3.4 Apr, 2011]
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