Result of FASTA (omim) for pF1KA0562
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KA0562, 925 aa
  1>>>pF1KA0562 925 - 925 aa - 925 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 7.3991+/-0.00044; mu= 12.8176+/- 0.028
 mean_var=151.4429+/-31.560, 0's: 0 Z-trim(115.7): 15  B-trim: 1435 in 1/51
 Lambda= 0.104220
 statistics sampled from 26265 (26280) to 26265 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.657), E-opt: 0.2 (0.308), width:  16
 Scan time: 12.230

The best scores are:                                      opt bits E(85289)
NP_055519 (OMIM: 616690,616781) centrosomal protei ( 925) 6118 932.6       0
XP_005244872 (OMIM: 616690,616781) PREDICTED: cent ( 961) 6118 932.6       0
XP_011540776 (OMIM: 616690,616781) PREDICTED: cent ( 931) 6096 929.3       0
XP_011540775 (OMIM: 616690,616781) PREDICTED: cent ( 967) 6096 929.3       0
XP_011540780 (OMIM: 616690,616781) PREDICTED: cent ( 777) 4633 709.3 1.9e-203
XP_016858407 (OMIM: 616690,616781) PREDICTED: cent ( 867) 3754 577.1 1.3e-163
XP_016858406 (OMIM: 616690,616781) PREDICTED: cent ( 903) 3754 577.1 1.3e-163
XP_011540777 (OMIM: 616690,616781) PREDICTED: cent ( 909) 3754 577.1 1.3e-163
XP_016858408 (OMIM: 616690,616781) PREDICTED: cent ( 859) 3199 493.7 1.7e-138
XP_011540778 (OMIM: 616690,616781) PREDICTED: cent ( 901) 3199 493.7 1.7e-138
XP_011540779 (OMIM: 616690,616781) PREDICTED: cent ( 843) 3191 492.5 3.8e-138


>>NP_055519 (OMIM: 616690,616781) centrosomal protein of  (925 aa)
 initn: 6118 init1: 6118 opt: 6118  Z-score: 4979.2  bits: 932.6 E(85289):    0
Smith-Waterman score: 6118; 100.0% identity (100.0% similar) in 925 aa overlap (1-925:1-925)

               10        20        30        40        50        60
pF1KA0 MPHKIGFVVVSSSGHEDGFSARELMIHAPTVSGWRSPRFCQFPQEIVLQMVERCRIRKLQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 MPHKIGFVVVSSSGHEDGFSARELMIHAPTVSGWRSPRFCQFPQEIVLQMVERCRIRKLQ
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KA0 LLAHQYMISSKIEFYISESLPEYFAPYQAERFRRLGYVSLCDNEKTGCKARELKSVYVDA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 LLAHQYMISSKIEFYISESLPEYFAPYQAERFRRLGYVSLCDNEKTGCKARELKSVYVDA
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KA0 VGQFLKLIFHQNHVNKYNIYNQVALVAINIIGDPADFSDESNTASREKLIDHYLGHNSED
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 VGQFLKLIFHQNHVNKYNIYNQVALVAINIIGDPADFSDESNTASREKLIDHYLGHNSED
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KA0 PALEGTYARKSDYISPLDDLAFDMYQDPEVAQIIRKLDERKREAVQKERYDYAKKLKQAI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 PALEGTYARKSDYISPLDDLAFDMYQDPEVAQIIRKLDERKREAVQKERYDYAKKLKQAI
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KA0 ADLQKVGERLGRYEVEKRCAVEKEDYDLAKEKKQQMEQYRAEVYEQLELHSLLDAELMRR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 ADLQKVGERLGRYEVEKRCAVEKEDYDLAKEKKQQMEQYRAEVYEQLELHSLLDAELMRR
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KA0 PFDLPLQPLARSGSPCHQKPMPSLPQLEERGTENQFAEPFLQEKPSSYSLTISPQHSAVD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 PFDLPLQPLARSGSPCHQKPMPSLPQLEERGTENQFAEPFLQEKPSSYSLTISPQHSAVD
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KA0 PLLPATDPHPKINAESLPYDERPLPAIRKHYGEAVVEPEMSNADISDARRGGMLGEPEPL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 PLLPATDPHPKINAESLPYDERPLPAIRKHYGEAVVEPEMSNADISDARRGGMLGEPEPL
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KA0 TEKALREASSAIDVLGETLVAEAYCKTWSYREDALLALSKKLMEMPVGTPKEDLKNTLRA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 TEKALREASSAIDVLGETLVAEAYCKTWSYREDALLALSKKLMEMPVGTPKEDLKNTLRA
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KA0 SVFLVRRAIKDIVTSVFQASLKLLKMIITQYIPKHKLSKLETAHCVERTIPVLLTRTGDS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 SVFLVRRAIKDIVTSVFQASLKLLKMIITQYIPKHKLSKLETAHCVERTIPVLLTRTGDS
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KA0 SARLRVTAANFIQEMALFKEVKSLQIIPSYLVQPLKANSSVHLAMSQMGLLARLLKDLGT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 SARLRVTAANFIQEMALFKEVKSLQIIPSYLVQPLKANSSVHLAMSQMGLLARLLKDLGT
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KA0 GSSGFTIDNVMKFSVSALEHRVYEVRETAVRIILDMYRQHQASILEYLPPDDSNTRRNIL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 GSSGFTIDNVMKFSVSALEHRVYEVRETAVRIILDMYRQHQASILEYLPPDDSNTRRNIL
              610       620       630       640       650       660

              670       680       690       700       710       720
pF1KA0 YKTIFEGFAKIDGRATDAEMRARRKAATEEAEKQKKEEIKALQGQLAALKEIQAEVQEKE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 YKTIFEGFAKIDGRATDAEMRARRKAATEEAEKQKKEEIKALQGQLAALKEIQAEVQEKE
              670       680       690       700       710       720

              730       740       750       760       770       780
pF1KA0 SDAVKPKNQDIQGGKAAPAEALGIPDEHYLDNLCIFCGERSESFTEEGLDLHYWKHCLML
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 SDAVKPKNQDIQGGKAAPAEALGIPDEHYLDNLCIFCGERSESFTEEGLDLHYWKHCLML
              730       740       750       760       770       780

              790       800       810       820       830       840
pF1KA0 TRCDHCKQVVEISSLTEHLLTECDKKDGFGKCYRCSEAVFKEELPRHIKHKDCNPAKPEK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 TRCDHCKQVVEISSLTEHLLTECDKKDGFGKCYRCSEAVFKEELPRHIKHKDCNPAKPEK
              790       800       810       820       830       840

              850       860       870       880       890       900
pF1KA0 LANRCPLCHENFSPGEEAWKAHLMGPAGCTMNLRKTHILQKAPALQPGKSSAVAASGPLG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 LANRCPLCHENFSPGEEAWKAHLMGPAGCTMNLRKTHILQKAPALQPGKSSAVAASGPLG
              850       860       870       880       890       900

              910       920     
pF1KA0 SKAGSKIPTPKGGLSKSSSRTYAKR
       :::::::::::::::::::::::::
NP_055 SKAGSKIPTPKGGLSKSSSRTYAKR
              910       920     

>>XP_005244872 (OMIM: 616690,616781) PREDICTED: centroso  (961 aa)
 initn: 6118 init1: 6118 opt: 6118  Z-score: 4978.9  bits: 932.6 E(85289):    0
Smith-Waterman score: 6118; 100.0% identity (100.0% similar) in 925 aa overlap (1-925:37-961)

                                             10        20        30
pF1KA0                               MPHKIGFVVVSSSGHEDGFSARELMIHAPT
                                     ::::::::::::::::::::::::::::::
XP_005 GERCTLAFVGMSMAAPGTTGIPHASAQTCRMPHKIGFVVVSSSGHEDGFSARELMIHAPT
         10        20        30        40        50        60      

               40        50        60        70        80        90
pF1KA0 VSGWRSPRFCQFPQEIVLQMVERCRIRKLQLLAHQYMISSKIEFYISESLPEYFAPYQAE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VSGWRSPRFCQFPQEIVLQMVERCRIRKLQLLAHQYMISSKIEFYISESLPEYFAPYQAE
         70        80        90       100       110       120      

              100       110       120       130       140       150
pF1KA0 RFRRLGYVSLCDNEKTGCKARELKSVYVDAVGQFLKLIFHQNHVNKYNIYNQVALVAINI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RFRRLGYVSLCDNEKTGCKARELKSVYVDAVGQFLKLIFHQNHVNKYNIYNQVALVAINI
        130       140       150       160       170       180      

              160       170       180       190       200       210
pF1KA0 IGDPADFSDESNTASREKLIDHYLGHNSEDPALEGTYARKSDYISPLDDLAFDMYQDPEV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 IGDPADFSDESNTASREKLIDHYLGHNSEDPALEGTYARKSDYISPLDDLAFDMYQDPEV
        190       200       210       220       230       240      

              220       230       240       250       260       270
pF1KA0 AQIIRKLDERKREAVQKERYDYAKKLKQAIADLQKVGERLGRYEVEKRCAVEKEDYDLAK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 AQIIRKLDERKREAVQKERYDYAKKLKQAIADLQKVGERLGRYEVEKRCAVEKEDYDLAK
        250       260       270       280       290       300      

              280       290       300       310       320       330
pF1KA0 EKKQQMEQYRAEVYEQLELHSLLDAELMRRPFDLPLQPLARSGSPCHQKPMPSLPQLEER
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EKKQQMEQYRAEVYEQLELHSLLDAELMRRPFDLPLQPLARSGSPCHQKPMPSLPQLEER
        310       320       330       340       350       360      

              340       350       360       370       380       390
pF1KA0 GTENQFAEPFLQEKPSSYSLTISPQHSAVDPLLPATDPHPKINAESLPYDERPLPAIRKH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GTENQFAEPFLQEKPSSYSLTISPQHSAVDPLLPATDPHPKINAESLPYDERPLPAIRKH
        370       380       390       400       410       420      

              400       410       420       430       440       450
pF1KA0 YGEAVVEPEMSNADISDARRGGMLGEPEPLTEKALREASSAIDVLGETLVAEAYCKTWSY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 YGEAVVEPEMSNADISDARRGGMLGEPEPLTEKALREASSAIDVLGETLVAEAYCKTWSY
        430       440       450       460       470       480      

              460       470       480       490       500       510
pF1KA0 REDALLALSKKLMEMPVGTPKEDLKNTLRASVFLVRRAIKDIVTSVFQASLKLLKMIITQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 REDALLALSKKLMEMPVGTPKEDLKNTLRASVFLVRRAIKDIVTSVFQASLKLLKMIITQ
        490       500       510       520       530       540      

              520       530       540       550       560       570
pF1KA0 YIPKHKLSKLETAHCVERTIPVLLTRTGDSSARLRVTAANFIQEMALFKEVKSLQIIPSY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 YIPKHKLSKLETAHCVERTIPVLLTRTGDSSARLRVTAANFIQEMALFKEVKSLQIIPSY
        550       560       570       580       590       600      

              580       590       600       610       620       630
pF1KA0 LVQPLKANSSVHLAMSQMGLLARLLKDLGTGSSGFTIDNVMKFSVSALEHRVYEVRETAV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LVQPLKANSSVHLAMSQMGLLARLLKDLGTGSSGFTIDNVMKFSVSALEHRVYEVRETAV
        610       620       630       640       650       660      

              640       650       660       670       680       690
pF1KA0 RIILDMYRQHQASILEYLPPDDSNTRRNILYKTIFEGFAKIDGRATDAEMRARRKAATEE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RIILDMYRQHQASILEYLPPDDSNTRRNILYKTIFEGFAKIDGRATDAEMRARRKAATEE
        670       680       690       700       710       720      

              700       710       720       730       740       750
pF1KA0 AEKQKKEEIKALQGQLAALKEIQAEVQEKESDAVKPKNQDIQGGKAAPAEALGIPDEHYL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 AEKQKKEEIKALQGQLAALKEIQAEVQEKESDAVKPKNQDIQGGKAAPAEALGIPDEHYL
        730       740       750       760       770       780      

              760       770       780       790       800       810
pF1KA0 DNLCIFCGERSESFTEEGLDLHYWKHCLMLTRCDHCKQVVEISSLTEHLLTECDKKDGFG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DNLCIFCGERSESFTEEGLDLHYWKHCLMLTRCDHCKQVVEISSLTEHLLTECDKKDGFG
        790       800       810       820       830       840      

              820       830       840       850       860       870
pF1KA0 KCYRCSEAVFKEELPRHIKHKDCNPAKPEKLANRCPLCHENFSPGEEAWKAHLMGPAGCT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KCYRCSEAVFKEELPRHIKHKDCNPAKPEKLANRCPLCHENFSPGEEAWKAHLMGPAGCT
        850       860       870       880       890       900      

              880       890       900       910       920     
pF1KA0 MNLRKTHILQKAPALQPGKSSAVAASGPLGSKAGSKIPTPKGGLSKSSSRTYAKR
       :::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MNLRKTHILQKAPALQPGKSSAVAASGPLGSKAGSKIPTPKGGLSKSSSRTYAKR
        910       920       930       940       950       960 

>>XP_011540776 (OMIM: 616690,616781) PREDICTED: centroso  (931 aa)
 initn: 5463 init1: 5463 opt: 6096  Z-score: 4961.3  bits: 929.3 E(85289):    0
Smith-Waterman score: 6096; 99.4% identity (99.4% similar) in 931 aa overlap (1-925:1-931)

               10        20        30        40        50        60
pF1KA0 MPHKIGFVVVSSSGHEDGFSARELMIHAPTVSGWRSPRFCQFPQEIVLQMVERCRIRKLQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MPHKIGFVVVSSSGHEDGFSARELMIHAPTVSGWRSPRFCQFPQEIVLQMVERCRIRKLQ
               10        20        30        40        50        60

               70        80        90             100       110    
pF1KA0 LLAHQYMISSKIEFYISESLPEYFAPYQAERFRRLG------YVSLCDNEKTGCKARELK
       ::::::::::::::::::::::::::::::::::::      ::::::::::::::::::
XP_011 LLAHQYMISSKIEFYISESLPEYFAPYQAERFRRLGCVLFFSYVSLCDNEKTGCKARELK
               70        80        90       100       110       120

          120       130       140       150       160       170    
pF1KA0 SVYVDAVGQFLKLIFHQNHVNKYNIYNQVALVAINIIGDPADFSDESNTASREKLIDHYL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SVYVDAVGQFLKLIFHQNHVNKYNIYNQVALVAINIIGDPADFSDESNTASREKLIDHYL
              130       140       150       160       170       180

          180       190       200       210       220       230    
pF1KA0 GHNSEDPALEGTYARKSDYISPLDDLAFDMYQDPEVAQIIRKLDERKREAVQKERYDYAK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GHNSEDPALEGTYARKSDYISPLDDLAFDMYQDPEVAQIIRKLDERKREAVQKERYDYAK
              190       200       210       220       230       240

          240       250       260       270       280       290    
pF1KA0 KLKQAIADLQKVGERLGRYEVEKRCAVEKEDYDLAKEKKQQMEQYRAEVYEQLELHSLLD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KLKQAIADLQKVGERLGRYEVEKRCAVEKEDYDLAKEKKQQMEQYRAEVYEQLELHSLLD
              250       260       270       280       290       300

          300       310       320       330       340       350    
pF1KA0 AELMRRPFDLPLQPLARSGSPCHQKPMPSLPQLEERGTENQFAEPFLQEKPSSYSLTISP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AELMRRPFDLPLQPLARSGSPCHQKPMPSLPQLEERGTENQFAEPFLQEKPSSYSLTISP
              310       320       330       340       350       360

          360       370       380       390       400       410    
pF1KA0 QHSAVDPLLPATDPHPKINAESLPYDERPLPAIRKHYGEAVVEPEMSNADISDARRGGML
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QHSAVDPLLPATDPHPKINAESLPYDERPLPAIRKHYGEAVVEPEMSNADISDARRGGML
              370       380       390       400       410       420

          420       430       440       450       460       470    
pF1KA0 GEPEPLTEKALREASSAIDVLGETLVAEAYCKTWSYREDALLALSKKLMEMPVGTPKEDL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GEPEPLTEKALREASSAIDVLGETLVAEAYCKTWSYREDALLALSKKLMEMPVGTPKEDL
              430       440       450       460       470       480

          480       490       500       510       520       530    
pF1KA0 KNTLRASVFLVRRAIKDIVTSVFQASLKLLKMIITQYIPKHKLSKLETAHCVERTIPVLL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KNTLRASVFLVRRAIKDIVTSVFQASLKLLKMIITQYIPKHKLSKLETAHCVERTIPVLL
              490       500       510       520       530       540

          540       550       560       570       580       590    
pF1KA0 TRTGDSSARLRVTAANFIQEMALFKEVKSLQIIPSYLVQPLKANSSVHLAMSQMGLLARL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TRTGDSSARLRVTAANFIQEMALFKEVKSLQIIPSYLVQPLKANSSVHLAMSQMGLLARL
              550       560       570       580       590       600

          600       610       620       630       640       650    
pF1KA0 LKDLGTGSSGFTIDNVMKFSVSALEHRVYEVRETAVRIILDMYRQHQASILEYLPPDDSN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LKDLGTGSSGFTIDNVMKFSVSALEHRVYEVRETAVRIILDMYRQHQASILEYLPPDDSN
              610       620       630       640       650       660

          660       670       680       690       700       710    
pF1KA0 TRRNILYKTIFEGFAKIDGRATDAEMRARRKAATEEAEKQKKEEIKALQGQLAALKEIQA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TRRNILYKTIFEGFAKIDGRATDAEMRARRKAATEEAEKQKKEEIKALQGQLAALKEIQA
              670       680       690       700       710       720

          720       730       740       750       760       770    
pF1KA0 EVQEKESDAVKPKNQDIQGGKAAPAEALGIPDEHYLDNLCIFCGERSESFTEEGLDLHYW
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EVQEKESDAVKPKNQDIQGGKAAPAEALGIPDEHYLDNLCIFCGERSESFTEEGLDLHYW
              730       740       750       760       770       780

          780       790       800       810       820       830    
pF1KA0 KHCLMLTRCDHCKQVVEISSLTEHLLTECDKKDGFGKCYRCSEAVFKEELPRHIKHKDCN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KHCLMLTRCDHCKQVVEISSLTEHLLTECDKKDGFGKCYRCSEAVFKEELPRHIKHKDCN
              790       800       810       820       830       840

          840       850       860       870       880       890    
pF1KA0 PAKPEKLANRCPLCHENFSPGEEAWKAHLMGPAGCTMNLRKTHILQKAPALQPGKSSAVA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PAKPEKLANRCPLCHENFSPGEEAWKAHLMGPAGCTMNLRKTHILQKAPALQPGKSSAVA
              850       860       870       880       890       900

          900       910       920     
pF1KA0 ASGPLGSKAGSKIPTPKGGLSKSSSRTYAKR
       :::::::::::::::::::::::::::::::
XP_011 ASGPLGSKAGSKIPTPKGGLSKSSSRTYAKR
              910       920       930 

>>XP_011540775 (OMIM: 616690,616781) PREDICTED: centroso  (967 aa)
 initn: 5463 init1: 5463 opt: 6096  Z-score: 4961.0  bits: 929.3 E(85289):    0
Smith-Waterman score: 6096; 99.4% identity (99.4% similar) in 931 aa overlap (1-925:37-967)

                                             10        20        30
pF1KA0                               MPHKIGFVVVSSSGHEDGFSARELMIHAPT
                                     ::::::::::::::::::::::::::::::
XP_011 GERCTLAFVGMSMAAPGTTGIPHASAQTCRMPHKIGFVVVSSSGHEDGFSARELMIHAPT
         10        20        30        40        50        60      

               40        50        60        70        80        90
pF1KA0 VSGWRSPRFCQFPQEIVLQMVERCRIRKLQLLAHQYMISSKIEFYISESLPEYFAPYQAE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VSGWRSPRFCQFPQEIVLQMVERCRIRKLQLLAHQYMISSKIEFYISESLPEYFAPYQAE
         70        80        90       100       110       120      

                    100       110       120       130       140    
pF1KA0 RFRRLG------YVSLCDNEKTGCKARELKSVYVDAVGQFLKLIFHQNHVNKYNIYNQVA
       ::::::      ::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RFRRLGCVLFFSYVSLCDNEKTGCKARELKSVYVDAVGQFLKLIFHQNHVNKYNIYNQVA
        130       140       150       160       170       180      

          150       160       170       180       190       200    
pF1KA0 LVAINIIGDPADFSDESNTASREKLIDHYLGHNSEDPALEGTYARKSDYISPLDDLAFDM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LVAINIIGDPADFSDESNTASREKLIDHYLGHNSEDPALEGTYARKSDYISPLDDLAFDM
        190       200       210       220       230       240      

          210       220       230       240       250       260    
pF1KA0 YQDPEVAQIIRKLDERKREAVQKERYDYAKKLKQAIADLQKVGERLGRYEVEKRCAVEKE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YQDPEVAQIIRKLDERKREAVQKERYDYAKKLKQAIADLQKVGERLGRYEVEKRCAVEKE
        250       260       270       280       290       300      

          270       280       290       300       310       320    
pF1KA0 DYDLAKEKKQQMEQYRAEVYEQLELHSLLDAELMRRPFDLPLQPLARSGSPCHQKPMPSL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DYDLAKEKKQQMEQYRAEVYEQLELHSLLDAELMRRPFDLPLQPLARSGSPCHQKPMPSL
        310       320       330       340       350       360      

          330       340       350       360       370       380    
pF1KA0 PQLEERGTENQFAEPFLQEKPSSYSLTISPQHSAVDPLLPATDPHPKINAESLPYDERPL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PQLEERGTENQFAEPFLQEKPSSYSLTISPQHSAVDPLLPATDPHPKINAESLPYDERPL
        370       380       390       400       410       420      

          390       400       410       420       430       440    
pF1KA0 PAIRKHYGEAVVEPEMSNADISDARRGGMLGEPEPLTEKALREASSAIDVLGETLVAEAY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PAIRKHYGEAVVEPEMSNADISDARRGGMLGEPEPLTEKALREASSAIDVLGETLVAEAY
        430       440       450       460       470       480      

          450       460       470       480       490       500    
pF1KA0 CKTWSYREDALLALSKKLMEMPVGTPKEDLKNTLRASVFLVRRAIKDIVTSVFQASLKLL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CKTWSYREDALLALSKKLMEMPVGTPKEDLKNTLRASVFLVRRAIKDIVTSVFQASLKLL
        490       500       510       520       530       540      

          510       520       530       540       550       560    
pF1KA0 KMIITQYIPKHKLSKLETAHCVERTIPVLLTRTGDSSARLRVTAANFIQEMALFKEVKSL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KMIITQYIPKHKLSKLETAHCVERTIPVLLTRTGDSSARLRVTAANFIQEMALFKEVKSL
        550       560       570       580       590       600      

          570       580       590       600       610       620    
pF1KA0 QIIPSYLVQPLKANSSVHLAMSQMGLLARLLKDLGTGSSGFTIDNVMKFSVSALEHRVYE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QIIPSYLVQPLKANSSVHLAMSQMGLLARLLKDLGTGSSGFTIDNVMKFSVSALEHRVYE
        610       620       630       640       650       660      

          630       640       650       660       670       680    
pF1KA0 VRETAVRIILDMYRQHQASILEYLPPDDSNTRRNILYKTIFEGFAKIDGRATDAEMRARR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VRETAVRIILDMYRQHQASILEYLPPDDSNTRRNILYKTIFEGFAKIDGRATDAEMRARR
        670       680       690       700       710       720      

          690       700       710       720       730       740    
pF1KA0 KAATEEAEKQKKEEIKALQGQLAALKEIQAEVQEKESDAVKPKNQDIQGGKAAPAEALGI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KAATEEAEKQKKEEIKALQGQLAALKEIQAEVQEKESDAVKPKNQDIQGGKAAPAEALGI
        730       740       750       760       770       780      

          750       760       770       780       790       800    
pF1KA0 PDEHYLDNLCIFCGERSESFTEEGLDLHYWKHCLMLTRCDHCKQVVEISSLTEHLLTECD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PDEHYLDNLCIFCGERSESFTEEGLDLHYWKHCLMLTRCDHCKQVVEISSLTEHLLTECD
        790       800       810       820       830       840      

          810       820       830       840       850       860    
pF1KA0 KKDGFGKCYRCSEAVFKEELPRHIKHKDCNPAKPEKLANRCPLCHENFSPGEEAWKAHLM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KKDGFGKCYRCSEAVFKEELPRHIKHKDCNPAKPEKLANRCPLCHENFSPGEEAWKAHLM
        850       860       870       880       890       900      

          870       880       890       900       910       920    
pF1KA0 GPAGCTMNLRKTHILQKAPALQPGKSSAVAASGPLGSKAGSKIPTPKGGLSKSSSRTYAK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GPAGCTMNLRKTHILQKAPALQPGKSSAVAASGPLGSKAGSKIPTPKGGLSKSSSRTYAK
        910       920       930       940       950       960      

        
pF1KA0 R
       :
XP_011 R
        

>>XP_011540780 (OMIM: 616690,616781) PREDICTED: centroso  (777 aa)
 initn: 4000 init1: 4000 opt: 4633  Z-score: 3773.5  bits: 709.3 E(85289): 1.9e-203
Smith-Waterman score: 4633; 99.2% identity (99.2% similar) in 723 aa overlap (1-717:37-759)

                                             10        20        30
pF1KA0                               MPHKIGFVVVSSSGHEDGFSARELMIHAPT
                                     ::::::::::::::::::::::::::::::
XP_011 GERCTLAFVGMSMAAPGTTGIPHASAQTCRMPHKIGFVVVSSSGHEDGFSARELMIHAPT
         10        20        30        40        50        60      

               40        50        60        70        80        90
pF1KA0 VSGWRSPRFCQFPQEIVLQMVERCRIRKLQLLAHQYMISSKIEFYISESLPEYFAPYQAE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VSGWRSPRFCQFPQEIVLQMVERCRIRKLQLLAHQYMISSKIEFYISESLPEYFAPYQAE
         70        80        90       100       110       120      

                    100       110       120       130       140    
pF1KA0 RFRRLG------YVSLCDNEKTGCKARELKSVYVDAVGQFLKLIFHQNHVNKYNIYNQVA
       ::::::      ::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RFRRLGCVLFFSYVSLCDNEKTGCKARELKSVYVDAVGQFLKLIFHQNHVNKYNIYNQVA
        130       140       150       160       170       180      

          150       160       170       180       190       200    
pF1KA0 LVAINIIGDPADFSDESNTASREKLIDHYLGHNSEDPALEGTYARKSDYISPLDDLAFDM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LVAINIIGDPADFSDESNTASREKLIDHYLGHNSEDPALEGTYARKSDYISPLDDLAFDM
        190       200       210       220       230       240      

          210       220       230       240       250       260    
pF1KA0 YQDPEVAQIIRKLDERKREAVQKERYDYAKKLKQAIADLQKVGERLGRYEVEKRCAVEKE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YQDPEVAQIIRKLDERKREAVQKERYDYAKKLKQAIADLQKVGERLGRYEVEKRCAVEKE
        250       260       270       280       290       300      

          270       280       290       300       310       320    
pF1KA0 DYDLAKEKKQQMEQYRAEVYEQLELHSLLDAELMRRPFDLPLQPLARSGSPCHQKPMPSL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DYDLAKEKKQQMEQYRAEVYEQLELHSLLDAELMRRPFDLPLQPLARSGSPCHQKPMPSL
        310       320       330       340       350       360      

          330       340       350       360       370       380    
pF1KA0 PQLEERGTENQFAEPFLQEKPSSYSLTISPQHSAVDPLLPATDPHPKINAESLPYDERPL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PQLEERGTENQFAEPFLQEKPSSYSLTISPQHSAVDPLLPATDPHPKINAESLPYDERPL
        370       380       390       400       410       420      

          390       400       410       420       430       440    
pF1KA0 PAIRKHYGEAVVEPEMSNADISDARRGGMLGEPEPLTEKALREASSAIDVLGETLVAEAY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PAIRKHYGEAVVEPEMSNADISDARRGGMLGEPEPLTEKALREASSAIDVLGETLVAEAY
        430       440       450       460       470       480      

          450       460       470       480       490       500    
pF1KA0 CKTWSYREDALLALSKKLMEMPVGTPKEDLKNTLRASVFLVRRAIKDIVTSVFQASLKLL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CKTWSYREDALLALSKKLMEMPVGTPKEDLKNTLRASVFLVRRAIKDIVTSVFQASLKLL
        490       500       510       520       530       540      

          510       520       530       540       550       560    
pF1KA0 KMIITQYIPKHKLSKLETAHCVERTIPVLLTRTGDSSARLRVTAANFIQEMALFKEVKSL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KMIITQYIPKHKLSKLETAHCVERTIPVLLTRTGDSSARLRVTAANFIQEMALFKEVKSL
        550       560       570       580       590       600      

          570       580       590       600       610       620    
pF1KA0 QIIPSYLVQPLKANSSVHLAMSQMGLLARLLKDLGTGSSGFTIDNVMKFSVSALEHRVYE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QIIPSYLVQPLKANSSVHLAMSQMGLLARLLKDLGTGSSGFTIDNVMKFSVSALEHRVYE
        610       620       630       640       650       660      

          630       640       650       660       670       680    
pF1KA0 VRETAVRIILDMYRQHQASILEYLPPDDSNTRRNILYKTIFEGFAKIDGRATDAEMRARR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VRETAVRIILDMYRQHQASILEYLPPDDSNTRRNILYKTIFEGFAKIDGRATDAEMRARR
        670       680       690       700       710       720      

          690       700       710       720       730       740    
pF1KA0 KAATEEAEKQKKEEIKALQGQLAALKEIQAEVQEKESDAVKPKNQDIQGGKAAPAEALGI
       :::::::::::::::::::::::::::::::::                           
XP_011 KAATEEAEKQKKEEIKALQGQLAALKEIQAEVQLSSHLQRQRRKISLTIKV         
        730       740       750       760       770                

          750       760       770       780       790       800    
pF1KA0 PDEHYLDNLCIFCGERSESFTEEGLDLHYWKHCLMLTRCDHCKQVVEISSLTEHLLTECD

>>XP_016858407 (OMIM: 616690,616781) PREDICTED: centroso  (867 aa)
 initn: 3751 init1: 3751 opt: 3754  Z-score: 3058.6  bits: 577.1 E(85289): 1.3e-163
Smith-Waterman score: 5585; 93.7% identity (93.7% similar) in 925 aa overlap (1-925:1-867)

               10        20        30        40        50        60
pF1KA0 MPHKIGFVVVSSSGHEDGFSARELMIHAPTVSGWRSPRFCQFPQEIVLQMVERCRIRKLQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MPHKIGFVVVSSSGHEDGFSARELMIHAPTVSGWRSPRFCQFPQEIVLQMVERCRIRKLQ
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KA0 LLAHQYMISSKIEFYISESLPEYFAPYQAERFRRLGYVSLCDNEKTGCKARELKSVYVDA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LLAHQYMISSKIEFYISESLPEYFAPYQAERFRRLGYVSLCDNEKTGCKARELKSVYVDA
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KA0 VGQFLKLIFHQNHVNKYNIYNQVALVAINIIGDPADFSDESNTASREKLIDHYLGHNSED
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VGQFLKLIFHQNHVNKYNIYNQVALVAINIIGDPADFSDESNTASREKLIDHYLGHNSED
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KA0 PALEGTYARKSDYISPLDDLAFDMYQDPEVAQIIRKLDERKREAVQKERYDYAKKLKQAI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PALEGTYARKSDYISPLDDLAFDMYQDPEVAQIIRKLDERKREAVQKERYDYAKKLKQAI
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KA0 ADLQKVGERLGRYEVEKRCAVEKEDYDLAKEKKQQMEQYRAEVYEQLELHSLLDAELMRR
       :::::::::::::::::::::::::::::::::::::::::::::::::::::::::   
XP_016 ADLQKVGERLGRYEVEKRCAVEKEDYDLAKEKKQQMEQYRAEVYEQLELHSLLDAEL---
              250       260       270       280       290          

              310       320       330       340       350       360
pF1KA0 PFDLPLQPLARSGSPCHQKPMPSLPQLEERGTENQFAEPFLQEKPSSYSLTISPQHSAVD
                                                              :::::
XP_016 -------------------------------------------------------HSAVD
                                                              300  

              370       380       390       400       410       420
pF1KA0 PLLPATDPHPKINAESLPYDERPLPAIRKHYGEAVVEPEMSNADISDARRGGMLGEPEPL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PLLPATDPHPKINAESLPYDERPLPAIRKHYGEAVVEPEMSNADISDARRGGMLGEPEPL
            310       320       330       340       350       360  

              430       440       450       460       470       480
pF1KA0 TEKALREASSAIDVLGETLVAEAYCKTWSYREDALLALSKKLMEMPVGTPKEDLKNTLRA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TEKALREASSAIDVLGETLVAEAYCKTWSYREDALLALSKKLMEMPVGTPKEDLKNTLRA
            370       380       390       400       410       420  

              490       500       510       520       530       540
pF1KA0 SVFLVRRAIKDIVTSVFQASLKLLKMIITQYIPKHKLSKLETAHCVERTIPVLLTRTGDS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SVFLVRRAIKDIVTSVFQASLKLLKMIITQYIPKHKLSKLETAHCVERTIPVLLTRTGDS
            430       440       450       460       470       480  

              550       560       570       580       590       600
pF1KA0 SARLRVTAANFIQEMALFKEVKSLQIIPSYLVQPLKANSSVHLAMSQMGLLARLLKDLGT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SARLRVTAANFIQEMALFKEVKSLQIIPSYLVQPLKANSSVHLAMSQMGLLARLLKDLGT
            490       500       510       520       530       540  

              610       620       630       640       650       660
pF1KA0 GSSGFTIDNVMKFSVSALEHRVYEVRETAVRIILDMYRQHQASILEYLPPDDSNTRRNIL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GSSGFTIDNVMKFSVSALEHRVYEVRETAVRIILDMYRQHQASILEYLPPDDSNTRRNIL
            550       560       570       580       590       600  

              670       680       690       700       710       720
pF1KA0 YKTIFEGFAKIDGRATDAEMRARRKAATEEAEKQKKEEIKALQGQLAALKEIQAEVQEKE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YKTIFEGFAKIDGRATDAEMRARRKAATEEAEKQKKEEIKALQGQLAALKEIQAEVQEKE
            610       620       630       640       650       660  

              730       740       750       760       770       780
pF1KA0 SDAVKPKNQDIQGGKAAPAEALGIPDEHYLDNLCIFCGERSESFTEEGLDLHYWKHCLML
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SDAVKPKNQDIQGGKAAPAEALGIPDEHYLDNLCIFCGERSESFTEEGLDLHYWKHCLML
            670       680       690       700       710       720  

              790       800       810       820       830       840
pF1KA0 TRCDHCKQVVEISSLTEHLLTECDKKDGFGKCYRCSEAVFKEELPRHIKHKDCNPAKPEK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TRCDHCKQVVEISSLTEHLLTECDKKDGFGKCYRCSEAVFKEELPRHIKHKDCNPAKPEK
            730       740       750       760       770       780  

              850       860       870       880       890       900
pF1KA0 LANRCPLCHENFSPGEEAWKAHLMGPAGCTMNLRKTHILQKAPALQPGKSSAVAASGPLG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LANRCPLCHENFSPGEEAWKAHLMGPAGCTMNLRKTHILQKAPALQPGKSSAVAASGPLG
            790       800       810       820       830       840  

              910       920     
pF1KA0 SKAGSKIPTPKGGLSKSSSRTYAKR
       :::::::::::::::::::::::::
XP_016 SKAGSKIPTPKGGLSKSSSRTYAKR
            850       860       

>>XP_016858406 (OMIM: 616690,616781) PREDICTED: centroso  (903 aa)
 initn: 3751 init1: 3751 opt: 3754  Z-score: 3058.3  bits: 577.1 E(85289): 1.3e-163
Smith-Waterman score: 5585; 93.7% identity (93.7% similar) in 925 aa overlap (1-925:37-903)

                                             10        20        30
pF1KA0                               MPHKIGFVVVSSSGHEDGFSARELMIHAPT
                                     ::::::::::::::::::::::::::::::
XP_016 GERCTLAFVGMSMAAPGTTGIPHASAQTCRMPHKIGFVVVSSSGHEDGFSARELMIHAPT
         10        20        30        40        50        60      

               40        50        60        70        80        90
pF1KA0 VSGWRSPRFCQFPQEIVLQMVERCRIRKLQLLAHQYMISSKIEFYISESLPEYFAPYQAE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VSGWRSPRFCQFPQEIVLQMVERCRIRKLQLLAHQYMISSKIEFYISESLPEYFAPYQAE
         70        80        90       100       110       120      

              100       110       120       130       140       150
pF1KA0 RFRRLGYVSLCDNEKTGCKARELKSVYVDAVGQFLKLIFHQNHVNKYNIYNQVALVAINI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RFRRLGYVSLCDNEKTGCKARELKSVYVDAVGQFLKLIFHQNHVNKYNIYNQVALVAINI
        130       140       150       160       170       180      

              160       170       180       190       200       210
pF1KA0 IGDPADFSDESNTASREKLIDHYLGHNSEDPALEGTYARKSDYISPLDDLAFDMYQDPEV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IGDPADFSDESNTASREKLIDHYLGHNSEDPALEGTYARKSDYISPLDDLAFDMYQDPEV
        190       200       210       220       230       240      

              220       230       240       250       260       270
pF1KA0 AQIIRKLDERKREAVQKERYDYAKKLKQAIADLQKVGERLGRYEVEKRCAVEKEDYDLAK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AQIIRKLDERKREAVQKERYDYAKKLKQAIADLQKVGERLGRYEVEKRCAVEKEDYDLAK
        250       260       270       280       290       300      

              280       290       300       310       320       330
pF1KA0 EKKQQMEQYRAEVYEQLELHSLLDAELMRRPFDLPLQPLARSGSPCHQKPMPSLPQLEER
       :::::::::::::::::::::::::::                                 
XP_016 EKKQQMEQYRAEVYEQLELHSLLDAEL---------------------------------
        310       320       330                                    

              340       350       360       370       380       390
pF1KA0 GTENQFAEPFLQEKPSSYSLTISPQHSAVDPLLPATDPHPKINAESLPYDERPLPAIRKH
                                :::::::::::::::::::::::::::::::::::
XP_016 -------------------------HSAVDPLLPATDPHPKINAESLPYDERPLPAIRKH
                                    340       350       360        

              400       410       420       430       440       450
pF1KA0 YGEAVVEPEMSNADISDARRGGMLGEPEPLTEKALREASSAIDVLGETLVAEAYCKTWSY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YGEAVVEPEMSNADISDARRGGMLGEPEPLTEKALREASSAIDVLGETLVAEAYCKTWSY
      370       380       390       400       410       420        

              460       470       480       490       500       510
pF1KA0 REDALLALSKKLMEMPVGTPKEDLKNTLRASVFLVRRAIKDIVTSVFQASLKLLKMIITQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 REDALLALSKKLMEMPVGTPKEDLKNTLRASVFLVRRAIKDIVTSVFQASLKLLKMIITQ
      430       440       450       460       470       480        

              520       530       540       550       560       570
pF1KA0 YIPKHKLSKLETAHCVERTIPVLLTRTGDSSARLRVTAANFIQEMALFKEVKSLQIIPSY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YIPKHKLSKLETAHCVERTIPVLLTRTGDSSARLRVTAANFIQEMALFKEVKSLQIIPSY
      490       500       510       520       530       540        

              580       590       600       610       620       630
pF1KA0 LVQPLKANSSVHLAMSQMGLLARLLKDLGTGSSGFTIDNVMKFSVSALEHRVYEVRETAV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LVQPLKANSSVHLAMSQMGLLARLLKDLGTGSSGFTIDNVMKFSVSALEHRVYEVRETAV
      550       560       570       580       590       600        

              640       650       660       670       680       690
pF1KA0 RIILDMYRQHQASILEYLPPDDSNTRRNILYKTIFEGFAKIDGRATDAEMRARRKAATEE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RIILDMYRQHQASILEYLPPDDSNTRRNILYKTIFEGFAKIDGRATDAEMRARRKAATEE
      610       620       630       640       650       660        

              700       710       720       730       740       750
pF1KA0 AEKQKKEEIKALQGQLAALKEIQAEVQEKESDAVKPKNQDIQGGKAAPAEALGIPDEHYL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AEKQKKEEIKALQGQLAALKEIQAEVQEKESDAVKPKNQDIQGGKAAPAEALGIPDEHYL
      670       680       690       700       710       720        

              760       770       780       790       800       810
pF1KA0 DNLCIFCGERSESFTEEGLDLHYWKHCLMLTRCDHCKQVVEISSLTEHLLTECDKKDGFG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DNLCIFCGERSESFTEEGLDLHYWKHCLMLTRCDHCKQVVEISSLTEHLLTECDKKDGFG
      730       740       750       760       770       780        

              820       830       840       850       860       870
pF1KA0 KCYRCSEAVFKEELPRHIKHKDCNPAKPEKLANRCPLCHENFSPGEEAWKAHLMGPAGCT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KCYRCSEAVFKEELPRHIKHKDCNPAKPEKLANRCPLCHENFSPGEEAWKAHLMGPAGCT
      790       800       810       820       830       840        

              880       890       900       910       920     
pF1KA0 MNLRKTHILQKAPALQPGKSSAVAASGPLGSKAGSKIPTPKGGLSKSSSRTYAKR
       :::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MNLRKTHILQKAPALQPGKSSAVAASGPLGSKAGSKIPTPKGGLSKSSSRTYAKR
      850       860       870       880       890       900   

>>XP_011540777 (OMIM: 616690,616781) PREDICTED: centroso  (909 aa)
 initn: 4452 init1: 3751 opt: 3754  Z-score: 3058.3  bits: 577.1 E(85289): 1.3e-163
Smith-Waterman score: 5563; 93.1% identity (93.1% similar) in 931 aa overlap (1-925:37-909)

                                             10        20        30
pF1KA0                               MPHKIGFVVVSSSGHEDGFSARELMIHAPT
                                     ::::::::::::::::::::::::::::::
XP_011 GERCTLAFVGMSMAAPGTTGIPHASAQTCRMPHKIGFVVVSSSGHEDGFSARELMIHAPT
         10        20        30        40        50        60      

               40        50        60        70        80        90
pF1KA0 VSGWRSPRFCQFPQEIVLQMVERCRIRKLQLLAHQYMISSKIEFYISESLPEYFAPYQAE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VSGWRSPRFCQFPQEIVLQMVERCRIRKLQLLAHQYMISSKIEFYISESLPEYFAPYQAE
         70        80        90       100       110       120      

                    100       110       120       130       140    
pF1KA0 RFRRLG------YVSLCDNEKTGCKARELKSVYVDAVGQFLKLIFHQNHVNKYNIYNQVA
       ::::::      ::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RFRRLGCVLFFSYVSLCDNEKTGCKARELKSVYVDAVGQFLKLIFHQNHVNKYNIYNQVA
        130       140       150       160       170       180      

          150       160       170       180       190       200    
pF1KA0 LVAINIIGDPADFSDESNTASREKLIDHYLGHNSEDPALEGTYARKSDYISPLDDLAFDM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LVAINIIGDPADFSDESNTASREKLIDHYLGHNSEDPALEGTYARKSDYISPLDDLAFDM
        190       200       210       220       230       240      

          210       220       230       240       250       260    
pF1KA0 YQDPEVAQIIRKLDERKREAVQKERYDYAKKLKQAIADLQKVGERLGRYEVEKRCAVEKE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YQDPEVAQIIRKLDERKREAVQKERYDYAKKLKQAIADLQKVGERLGRYEVEKRCAVEKE
        250       260       270       280       290       300      

          270       280       290       300       310       320    
pF1KA0 DYDLAKEKKQQMEQYRAEVYEQLELHSLLDAELMRRPFDLPLQPLARSGSPCHQKPMPSL
       :::::::::::::::::::::::::::::::::                           
XP_011 DYDLAKEKKQQMEQYRAEVYEQLELHSLLDAEL---------------------------
        310       320       330                                    

          330       340       350       360       370       380    
pF1KA0 PQLEERGTENQFAEPFLQEKPSSYSLTISPQHSAVDPLLPATDPHPKINAESLPYDERPL
                                      :::::::::::::::::::::::::::::
XP_011 -------------------------------HSAVDPLLPATDPHPKINAESLPYDERPL
                                    340       350       360        

          390       400       410       420       430       440    
pF1KA0 PAIRKHYGEAVVEPEMSNADISDARRGGMLGEPEPLTEKALREASSAIDVLGETLVAEAY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PAIRKHYGEAVVEPEMSNADISDARRGGMLGEPEPLTEKALREASSAIDVLGETLVAEAY
      370       380       390       400       410       420        

          450       460       470       480       490       500    
pF1KA0 CKTWSYREDALLALSKKLMEMPVGTPKEDLKNTLRASVFLVRRAIKDIVTSVFQASLKLL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CKTWSYREDALLALSKKLMEMPVGTPKEDLKNTLRASVFLVRRAIKDIVTSVFQASLKLL
      430       440       450       460       470       480        

          510       520       530       540       550       560    
pF1KA0 KMIITQYIPKHKLSKLETAHCVERTIPVLLTRTGDSSARLRVTAANFIQEMALFKEVKSL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KMIITQYIPKHKLSKLETAHCVERTIPVLLTRTGDSSARLRVTAANFIQEMALFKEVKSL
      490       500       510       520       530       540        

          570       580       590       600       610       620    
pF1KA0 QIIPSYLVQPLKANSSVHLAMSQMGLLARLLKDLGTGSSGFTIDNVMKFSVSALEHRVYE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QIIPSYLVQPLKANSSVHLAMSQMGLLARLLKDLGTGSSGFTIDNVMKFSVSALEHRVYE
      550       560       570       580       590       600        

          630       640       650       660       670       680    
pF1KA0 VRETAVRIILDMYRQHQASILEYLPPDDSNTRRNILYKTIFEGFAKIDGRATDAEMRARR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VRETAVRIILDMYRQHQASILEYLPPDDSNTRRNILYKTIFEGFAKIDGRATDAEMRARR
      610       620       630       640       650       660        

          690       700       710       720       730       740    
pF1KA0 KAATEEAEKQKKEEIKALQGQLAALKEIQAEVQEKESDAVKPKNQDIQGGKAAPAEALGI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KAATEEAEKQKKEEIKALQGQLAALKEIQAEVQEKESDAVKPKNQDIQGGKAAPAEALGI
      670       680       690       700       710       720        

          750       760       770       780       790       800    
pF1KA0 PDEHYLDNLCIFCGERSESFTEEGLDLHYWKHCLMLTRCDHCKQVVEISSLTEHLLTECD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PDEHYLDNLCIFCGERSESFTEEGLDLHYWKHCLMLTRCDHCKQVVEISSLTEHLLTECD
      730       740       750       760       770       780        

          810       820       830       840       850       860    
pF1KA0 KKDGFGKCYRCSEAVFKEELPRHIKHKDCNPAKPEKLANRCPLCHENFSPGEEAWKAHLM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KKDGFGKCYRCSEAVFKEELPRHIKHKDCNPAKPEKLANRCPLCHENFSPGEEAWKAHLM
      790       800       810       820       830       840        

          870       880       890       900       910       920    
pF1KA0 GPAGCTMNLRKTHILQKAPALQPGKSSAVAASGPLGSKAGSKIPTPKGGLSKSSSRTYAK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GPAGCTMNLRKTHILQKAPALQPGKSSAVAASGPLGSKAGSKIPTPKGGLSKSSSRTYAK
      850       860       870       880       890       900        

        
pF1KA0 R
       :
XP_011 R
        

>>XP_016858408 (OMIM: 616690,616781) PREDICTED: centroso  (859 aa)
 initn: 5678 init1: 3191 opt: 3199  Z-score: 2607.6  bits: 493.7 E(85289): 1.7e-138
Smith-Waterman score: 5550; 92.9% identity (92.9% similar) in 925 aa overlap (1-925:1-859)

               10        20        30        40        50        60
pF1KA0 MPHKIGFVVVSSSGHEDGFSARELMIHAPTVSGWRSPRFCQFPQEIVLQMVERCRIRKLQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MPHKIGFVVVSSSGHEDGFSARELMIHAPTVSGWRSPRFCQFPQEIVLQMVERCRIRKLQ
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KA0 LLAHQYMISSKIEFYISESLPEYFAPYQAERFRRLGYVSLCDNEKTGCKARELKSVYVDA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LLAHQYMISSKIEFYISESLPEYFAPYQAERFRRLGYVSLCDNEKTGCKARELKSVYVDA
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KA0 VGQFLKLIFHQNHVNKYNIYNQVALVAINIIGDPADFSDESNTASREKLIDHYLGHNSED
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VGQFLKLIFHQNHVNKYNIYNQVALVAINIIGDPADFSDESNTASREKLIDHYLGHNSED
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KA0 PALEGTYARKSDYISPLDDLAFDMYQDPEVAQIIRKLDERKREAVQKERYDYAKKLKQAI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PALEGTYARKSDYISPLDDLAFDMYQDPEVAQIIRKLDERKREAVQKERYDYAKKLKQAI
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KA0 ADLQKVGERLGRYEVEKRCAVEKEDYDLAKEKKQQMEQYRAEVYEQLELHSLLDAELMRR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ADLQKVGERLGRYEVEKRCAVEKEDYDLAKEKKQQMEQYRAEVYEQLELHSLLDAELMRR
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KA0 PFDLPLQPLARSGSPCHQKPMPSLPQLEERGTENQFAEPFLQEKPSSYSLTISPQHSAVD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PFDLPLQPLARSGSPCHQKPMPSLPQLEERGTENQFAEPFLQEKPSSYSLTISPQHSAVD
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KA0 PLLPATDPHPKINAESLPYDERPLPAIRKHYGEAVVEPEMSNADISDARRGGMLGEPEPL
       :::::::::::::                                               
XP_016 PLLPATDPHPKIN-----------------------------------------------
              370                                                  

              430       440       450       460       470       480
pF1KA0 TEKALREASSAIDVLGETLVAEAYCKTWSYREDALLALSKKLMEMPVGTPKEDLKNTLRA
                          :::::::::::::::::::::::::::::::::::::::::
XP_016 -------------------VAEAYCKTWSYREDALLALSKKLMEMPVGTPKEDLKNTLRA
                              380       390       400       410    

              490       500       510       520       530       540
pF1KA0 SVFLVRRAIKDIVTSVFQASLKLLKMIITQYIPKHKLSKLETAHCVERTIPVLLTRTGDS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SVFLVRRAIKDIVTSVFQASLKLLKMIITQYIPKHKLSKLETAHCVERTIPVLLTRTGDS
          420       430       440       450       460       470    

              550       560       570       580       590       600
pF1KA0 SARLRVTAANFIQEMALFKEVKSLQIIPSYLVQPLKANSSVHLAMSQMGLLARLLKDLGT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SARLRVTAANFIQEMALFKEVKSLQIIPSYLVQPLKANSSVHLAMSQMGLLARLLKDLGT
          480       490       500       510       520       530    

              610       620       630       640       650       660
pF1KA0 GSSGFTIDNVMKFSVSALEHRVYEVRETAVRIILDMYRQHQASILEYLPPDDSNTRRNIL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GSSGFTIDNVMKFSVSALEHRVYEVRETAVRIILDMYRQHQASILEYLPPDDSNTRRNIL
          540       550       560       570       580       590    

              670       680       690       700       710       720
pF1KA0 YKTIFEGFAKIDGRATDAEMRARRKAATEEAEKQKKEEIKALQGQLAALKEIQAEVQEKE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YKTIFEGFAKIDGRATDAEMRARRKAATEEAEKQKKEEIKALQGQLAALKEIQAEVQEKE
          600       610       620       630       640       650    

              730       740       750       760       770       780
pF1KA0 SDAVKPKNQDIQGGKAAPAEALGIPDEHYLDNLCIFCGERSESFTEEGLDLHYWKHCLML
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SDAVKPKNQDIQGGKAAPAEALGIPDEHYLDNLCIFCGERSESFTEEGLDLHYWKHCLML
          660       670       680       690       700       710    

              790       800       810       820       830       840
pF1KA0 TRCDHCKQVVEISSLTEHLLTECDKKDGFGKCYRCSEAVFKEELPRHIKHKDCNPAKPEK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TRCDHCKQVVEISSLTEHLLTECDKKDGFGKCYRCSEAVFKEELPRHIKHKDCNPAKPEK
          720       730       740       750       760       770    

              850       860       870       880       890       900
pF1KA0 LANRCPLCHENFSPGEEAWKAHLMGPAGCTMNLRKTHILQKAPALQPGKSSAVAASGPLG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LANRCPLCHENFSPGEEAWKAHLMGPAGCTMNLRKTHILQKAPALQPGKSSAVAASGPLG
          780       790       800       810       820       830    

              910       920     
pF1KA0 SKAGSKIPTPKGGLSKSSSRTYAKR
       :::::::::::::::::::::::::
XP_016 SKAGSKIPTPKGGLSKSSSRTYAKR
          840       850         

>>XP_011540778 (OMIM: 616690,616781) PREDICTED: centroso  (901 aa)
 initn: 5023 init1: 3191 opt: 3199  Z-score: 2607.4  bits: 493.7 E(85289): 1.7e-138
Smith-Waterman score: 5528; 92.3% identity (92.3% similar) in 931 aa overlap (1-925:37-901)

                                             10        20        30
pF1KA0                               MPHKIGFVVVSSSGHEDGFSARELMIHAPT
                                     ::::::::::::::::::::::::::::::
XP_011 GERCTLAFVGMSMAAPGTTGIPHASAQTCRMPHKIGFVVVSSSGHEDGFSARELMIHAPT
         10        20        30        40        50        60      

               40        50        60        70        80        90
pF1KA0 VSGWRSPRFCQFPQEIVLQMVERCRIRKLQLLAHQYMISSKIEFYISESLPEYFAPYQAE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VSGWRSPRFCQFPQEIVLQMVERCRIRKLQLLAHQYMISSKIEFYISESLPEYFAPYQAE
         70        80        90       100       110       120      

                    100       110       120       130       140    
pF1KA0 RFRRLG------YVSLCDNEKTGCKARELKSVYVDAVGQFLKLIFHQNHVNKYNIYNQVA
       ::::::      ::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RFRRLGCVLFFSYVSLCDNEKTGCKARELKSVYVDAVGQFLKLIFHQNHVNKYNIYNQVA
        130       140       150       160       170       180      

          150       160       170       180       190       200    
pF1KA0 LVAINIIGDPADFSDESNTASREKLIDHYLGHNSEDPALEGTYARKSDYISPLDDLAFDM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LVAINIIGDPADFSDESNTASREKLIDHYLGHNSEDPALEGTYARKSDYISPLDDLAFDM
        190       200       210       220       230       240      

          210       220       230       240       250       260    
pF1KA0 YQDPEVAQIIRKLDERKREAVQKERYDYAKKLKQAIADLQKVGERLGRYEVEKRCAVEKE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YQDPEVAQIIRKLDERKREAVQKERYDYAKKLKQAIADLQKVGERLGRYEVEKRCAVEKE
        250       260       270       280       290       300      

          270       280       290       300       310       320    
pF1KA0 DYDLAKEKKQQMEQYRAEVYEQLELHSLLDAELMRRPFDLPLQPLARSGSPCHQKPMPSL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DYDLAKEKKQQMEQYRAEVYEQLELHSLLDAELMRRPFDLPLQPLARSGSPCHQKPMPSL
        310       320       330       340       350       360      

          330       340       350       360       370       380    
pF1KA0 PQLEERGTENQFAEPFLQEKPSSYSLTISPQHSAVDPLLPATDPHPKINAESLPYDERPL
       :::::::::::::::::::::::::::::::::::::::::::::::::           
XP_011 PQLEERGTENQFAEPFLQEKPSSYSLTISPQHSAVDPLLPATDPHPKIN-----------
        370       380       390       400       410                

          390       400       410       420       430       440    
pF1KA0 PAIRKHYGEAVVEPEMSNADISDARRGGMLGEPEPLTEKALREASSAIDVLGETLVAEAY
                                                              :::::
XP_011 -------------------------------------------------------VAEAY
                                                                420

          450       460       470       480       490       500    
pF1KA0 CKTWSYREDALLALSKKLMEMPVGTPKEDLKNTLRASVFLVRRAIKDIVTSVFQASLKLL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CKTWSYREDALLALSKKLMEMPVGTPKEDLKNTLRASVFLVRRAIKDIVTSVFQASLKLL
              430       440       450       460       470       480

          510       520       530       540       550       560    
pF1KA0 KMIITQYIPKHKLSKLETAHCVERTIPVLLTRTGDSSARLRVTAANFIQEMALFKEVKSL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KMIITQYIPKHKLSKLETAHCVERTIPVLLTRTGDSSARLRVTAANFIQEMALFKEVKSL
              490       500       510       520       530       540

          570       580       590       600       610       620    
pF1KA0 QIIPSYLVQPLKANSSVHLAMSQMGLLARLLKDLGTGSSGFTIDNVMKFSVSALEHRVYE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QIIPSYLVQPLKANSSVHLAMSQMGLLARLLKDLGTGSSGFTIDNVMKFSVSALEHRVYE
              550       560       570       580       590       600

          630       640       650       660       670       680    
pF1KA0 VRETAVRIILDMYRQHQASILEYLPPDDSNTRRNILYKTIFEGFAKIDGRATDAEMRARR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VRETAVRIILDMYRQHQASILEYLPPDDSNTRRNILYKTIFEGFAKIDGRATDAEMRARR
              610       620       630       640       650       660

          690       700       710       720       730       740    
pF1KA0 KAATEEAEKQKKEEIKALQGQLAALKEIQAEVQEKESDAVKPKNQDIQGGKAAPAEALGI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KAATEEAEKQKKEEIKALQGQLAALKEIQAEVQEKESDAVKPKNQDIQGGKAAPAEALGI
              670       680       690       700       710       720

          750       760       770       780       790       800    
pF1KA0 PDEHYLDNLCIFCGERSESFTEEGLDLHYWKHCLMLTRCDHCKQVVEISSLTEHLLTECD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PDEHYLDNLCIFCGERSESFTEEGLDLHYWKHCLMLTRCDHCKQVVEISSLTEHLLTECD
              730       740       750       760       770       780

          810       820       830       840       850       860    
pF1KA0 KKDGFGKCYRCSEAVFKEELPRHIKHKDCNPAKPEKLANRCPLCHENFSPGEEAWKAHLM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KKDGFGKCYRCSEAVFKEELPRHIKHKDCNPAKPEKLANRCPLCHENFSPGEEAWKAHLM
              790       800       810       820       830       840

          870       880       890       900       910       920    
pF1KA0 GPAGCTMNLRKTHILQKAPALQPGKSSAVAASGPLGSKAGSKIPTPKGGLSKSSSRTYAK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GPAGCTMNLRKTHILQKAPALQPGKSSAVAASGPLGSKAGSKIPTPKGGLSKSSSRTYAK
              850       860       870       880       890       900

        
pF1KA0 R
       :
XP_011 R
        




925 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Wed Nov  2 19:16:46 2016 done: Wed Nov  2 19:16:47 2016
 Total Scan time: 12.230 Total Display time:  0.260

Function used was FASTA [36.3.4 Apr, 2011]
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