Result of FASTA (omim) for pF1KA0130
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KA0130, 989 aa
  1>>>pF1KA0130 989 - 989 aa - 989 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 6.0732+/-0.000469; mu= 16.7696+/- 0.029
 mean_var=74.0409+/-14.953, 0's: 0 Z-trim(108.4): 55  B-trim: 0 in 0/53
 Lambda= 0.149052
 statistics sampled from 16458 (16492) to 16458 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.546), E-opt: 0.2 (0.193), width:  16
 Scan time: 11.930

The best scores are:                                      opt bits E(85289)
NP_055630 (OMIM: 607000) mediator of RNA polymeras ( 989) 6481 1404.1       0
XP_016880955 (OMIM: 607000) PREDICTED: mediator of ( 989) 6481 1404.1       0
XP_005257931 (OMIM: 607000) PREDICTED: mediator of (1014) 6481 1404.1       0
XP_016880956 (OMIM: 607000) PREDICTED: mediator of ( 988) 6458 1399.2       0
XP_016880957 (OMIM: 607000) PREDICTED: mediator of ( 988) 6458 1399.2       0
NP_001254726 (OMIM: 607000) mediator of RNA polyme ( 976) 5948 1289.5       0
NP_001072986 (OMIM: 607000) mediator of RNA polyme ( 976) 5948 1289.5       0
XP_016880948 (OMIM: 607000) PREDICTED: mediator of (1032) 5758 1248.7       0
XP_011523833 (OMIM: 607000) PREDICTED: mediator of (1032) 5758 1248.7       0
NP_001317140 (OMIM: 607000) mediator of RNA polyme (1008) 5256 1140.7       0
XP_016880949 (OMIM: 607000) PREDICTED: mediator of (1008) 5256 1140.7       0
XP_016880950 (OMIM: 607000) PREDICTED: mediator of (1033) 5256 1140.7       0
XP_016880959 (OMIM: 607000) PREDICTED: mediator of ( 892) 5255 1140.5       0
XP_016880952 (OMIM: 607000) PREDICTED: mediator of (1007) 5233 1135.8       0
XP_016880951 (OMIM: 607000) PREDICTED: mediator of (1007) 5233 1135.8       0
XP_011523832 (OMIM: 607000) PREDICTED: mediator of (1051) 4533 985.3       0
XP_016880947 (OMIM: 607000) PREDICTED: mediator of (1051) 4533 985.3       0
XP_016880958 (OMIM: 607000) PREDICTED: mediator of ( 935) 4532 985.0       0
XP_016880953 (OMIM: 607000) PREDICTED: mediator of (1001) 3723 811.1       0
XP_011523836 (OMIM: 607000) PREDICTED: mediator of (1020) 3723 811.1       0
XP_016880954 (OMIM: 607000) PREDICTED: mediator of (1026) 3723 811.1       0
XP_011523837 (OMIM: 607000) PREDICTED: mediator of (1019) 3700 806.1       0
XP_011523840 (OMIM: 607000) PREDICTED: mediator of ( 947) 3000 655.6 3.5e-187
XP_006722270 (OMIM: 607000) PREDICTED: mediator of (1044) 3000 655.6 3.9e-187
XP_006722269 (OMIM: 607000) PREDICTED: mediator of (1044) 3000 655.6 3.9e-187
XP_011523834 (OMIM: 607000) PREDICTED: mediator of (1063) 3000 655.6 3.9e-187
XP_011523835 (OMIM: 607000) PREDICTED: mediator of (1063) 3000 655.6 3.9e-187
XP_006722267 (OMIM: 607000) PREDICTED: mediator of (1069) 3000 655.6 3.9e-187
XP_011523831 (OMIM: 607000) PREDICTED: mediator of (1088) 3000 655.6  4e-187
XP_016880960 (OMIM: 607000) PREDICTED: mediator of ( 523) 1549 343.5 1.7e-93


>>NP_055630 (OMIM: 607000) mediator of RNA polymerase II  (989 aa)
 initn: 6481 init1: 6481 opt: 6481  Z-score: 7526.6  bits: 1404.1 E(85289):    0
Smith-Waterman score: 6481; 99.8% identity (99.9% similar) in 989 aa overlap (1-989:1-989)

               10        20        30        40        50        60
pF1KA0 MKVVNLKQAILQAWKERWSYYQWAINMKKFFPKGATWDILNLADALLEQAMIGPSPNPLI
       ::::::::::::::::::: ::::::::::::::::::::::::::::::::::::::::
NP_055 MKVVNLKQAILQAWKERWSDYQWAINMKKFFPKGATWDILNLADALLEQAMIGPSPNPLI
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KA0 LSYLKYAISSQMVSYSSVLTAISKFDDFSRDLCVQALLDIMDMFCDRLSCHGKAEECIGL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 LSYLKYAISSQMVSYSSVLTAISKFDDFSRDLCVQALLDIMDMFCDRLSCHGKAEECIGL
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KA0 CRALLSALHWLLRCTAASAERLREGLEAGTPAAGEKQLAMCLQRLEKTLSSTKNRALLHI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 CRALLSALHWLLRCTAASAERLREGLEAGTPAAGEKQLAMCLQRLEKTLSSTKNRALLHI
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KA0 AKLEEASSWTAIEHSLLKLGEILTNLSNPQLRSQAEQCGTLIRSIPTMLSVHAEQMHKTG
       :::::::::::::::::::::::.::::::::::::::::::::::::::::::::::::
NP_055 AKLEEASSWTAIEHSLLKLGEILANLSNPQLRSQAEQCGTLIRSIPTMLSVHAEQMHKTG
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KA0 FPTVHAVILLEGTMNLTGETQSLVEQLTMVKRMQHIPTPLFVLEIWKACFVGLIESPEGT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 FPTVHAVILLEGTMNLTGETQSLVEQLTMVKRMQHIPTPLFVLEIWKACFVGLIESPEGT
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KA0 EELKWTAFTFLKIPQVLVKLKKYSHGDKDFTEDVNCAFEFLLKLTPLLDKADQRCNCDCT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 EELKWTAFTFLKIPQVLVKLKKYSHGDKDFTEDVNCAFEFLLKLTPLLDKADQRCNCDCT
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KA0 NFLLQECGKQGLLSEASVNNLMAKRKADREHAPQQKSGENANIQPNIQLILRAEPTVTNI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 NFLLQECGKQGLLSEASVNNLMAKRKADREHAPQQKSGENANIQPNIQLILRAEPTVTNI
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KA0 LKTMDADHSKSPEGLLGVLGHMLSGKSLDLLLAAAAATGKLKSFARKFINLNEFTTYGSE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 LKTMDADHSKSPEGLLGVLGHMLSGKSLDLLLAAAAATGKLKSFARKFINLNEFTTYGSE
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KA0 ESTKPASVRALLFDISFLMLCHVAQTYGSEVILSESRTGAEVPFFETWMQTCMPEEGKIL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 ESTKPASVRALLFDISFLMLCHVAQTYGSEVILSESRTGAEVPFFETWMQTCMPEEGKIL
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KA0 NPDHPCFRPDSTKVESLVALLNNSSEMKLVQMKWHEACLSISAAILEILNAWENGVLAFE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 NPDHPCFRPDSTKVESLVALLNNSSEMKLVQMKWHEACLSISAAILEILNAWENGVLAFE
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KA0 SIQKITDNIKGKVCSLAVCAVAWLVAHVRMLGLDEREKSLQMIRQLAGPLFSENTLQFYN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 SIQKITDNIKGKVCSLAVCAVAWLVAHVRMLGLDEREKSLQMIRQLAGPLFSENTLQFYN
              610       620       630       640       650       660

              670       680       690       700       710       720
pF1KA0 ERVVIMNSILERMCADVLQQTATQIKFPSTGVDTMPYWNLLPPKRPIKEVLTDIFAKVLE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 ERVVIMNSILERMCADVLQQTATQIKFPSTGVDTMPYWNLLPPKRPIKEVLTDIFAKVLE
              670       680       690       700       710       720

              730       740       750       760       770       780
pF1KA0 KGWVDSRSIHIFDTLLHMGGVYWFCNNLIKELLKETRKEHTLRAVELLYSIFCLDMQQVT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 KGWVDSRSIHIFDTLLHMGGVYWFCNNLIKELLKETRKEHTLRAVELLYSIFCLDMQQVT
              730       740       750       760       770       780

              790       800       810       820       830       840
pF1KA0 LVLLGHILPGLLTDSSKWHSLMDPPGTALAKLAVWCALSSYSSHKGQASTRQKKRHREDI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 LVLLGHILPGLLTDSSKWHSLMDPPGTALAKLAVWCALSSYSSHKGQASTRQKKRHREDI
              790       800       810       820       830       840

              850       860       870       880       890       900
pF1KA0 EDYISLFPLDDVQPSKLMRLLSSNEDDANILSSPTDRSMSSSLSASQLHTVNMRDPLNRV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 EDYISLFPLDDVQPSKLMRLLSSNEDDANILSSPTDRSMSSSLSASQLHTVNMRDPLNRV
              850       860       870       880       890       900

              910       920       930       940       950       960
pF1KA0 LANLFLLISSILGSRTAGPHTQFVQWFMEECVDCLEQGGRGSVLQFMPFTTVSELVKVSA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 LANLFLLISSILGSRTAGPHTQFVQWFMEECVDCLEQGGRGSVLQFMPFTTVSELVKVSA
              910       920       930       940       950       960

              970       980         
pF1KA0 MSSPKVVLAITDLSLPLGRQVAAKAIAAL
       :::::::::::::::::::::::::::::
NP_055 MSSPKVVLAITDLSLPLGRQVAAKAIAAL
              970       980         

>>XP_016880955 (OMIM: 607000) PREDICTED: mediator of RNA  (989 aa)
 initn: 6481 init1: 6481 opt: 6481  Z-score: 7526.6  bits: 1404.1 E(85289):    0
Smith-Waterman score: 6481; 99.8% identity (99.9% similar) in 989 aa overlap (1-989:1-989)

               10        20        30        40        50        60
pF1KA0 MKVVNLKQAILQAWKERWSYYQWAINMKKFFPKGATWDILNLADALLEQAMIGPSPNPLI
       ::::::::::::::::::: ::::::::::::::::::::::::::::::::::::::::
XP_016 MKVVNLKQAILQAWKERWSDYQWAINMKKFFPKGATWDILNLADALLEQAMIGPSPNPLI
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KA0 LSYLKYAISSQMVSYSSVLTAISKFDDFSRDLCVQALLDIMDMFCDRLSCHGKAEECIGL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LSYLKYAISSQMVSYSSVLTAISKFDDFSRDLCVQALLDIMDMFCDRLSCHGKAEECIGL
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KA0 CRALLSALHWLLRCTAASAERLREGLEAGTPAAGEKQLAMCLQRLEKTLSSTKNRALLHI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CRALLSALHWLLRCTAASAERLREGLEAGTPAAGEKQLAMCLQRLEKTLSSTKNRALLHI
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KA0 AKLEEASSWTAIEHSLLKLGEILTNLSNPQLRSQAEQCGTLIRSIPTMLSVHAEQMHKTG
       :::::::::::::::::::::::.::::::::::::::::::::::::::::::::::::
XP_016 AKLEEASSWTAIEHSLLKLGEILANLSNPQLRSQAEQCGTLIRSIPTMLSVHAEQMHKTG
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KA0 FPTVHAVILLEGTMNLTGETQSLVEQLTMVKRMQHIPTPLFVLEIWKACFVGLIESPEGT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FPTVHAVILLEGTMNLTGETQSLVEQLTMVKRMQHIPTPLFVLEIWKACFVGLIESPEGT
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KA0 EELKWTAFTFLKIPQVLVKLKKYSHGDKDFTEDVNCAFEFLLKLTPLLDKADQRCNCDCT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EELKWTAFTFLKIPQVLVKLKKYSHGDKDFTEDVNCAFEFLLKLTPLLDKADQRCNCDCT
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KA0 NFLLQECGKQGLLSEASVNNLMAKRKADREHAPQQKSGENANIQPNIQLILRAEPTVTNI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NFLLQECGKQGLLSEASVNNLMAKRKADREHAPQQKSGENANIQPNIQLILRAEPTVTNI
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KA0 LKTMDADHSKSPEGLLGVLGHMLSGKSLDLLLAAAAATGKLKSFARKFINLNEFTTYGSE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LKTMDADHSKSPEGLLGVLGHMLSGKSLDLLLAAAAATGKLKSFARKFINLNEFTTYGSE
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KA0 ESTKPASVRALLFDISFLMLCHVAQTYGSEVILSESRTGAEVPFFETWMQTCMPEEGKIL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ESTKPASVRALLFDISFLMLCHVAQTYGSEVILSESRTGAEVPFFETWMQTCMPEEGKIL
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KA0 NPDHPCFRPDSTKVESLVALLNNSSEMKLVQMKWHEACLSISAAILEILNAWENGVLAFE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NPDHPCFRPDSTKVESLVALLNNSSEMKLVQMKWHEACLSISAAILEILNAWENGVLAFE
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KA0 SIQKITDNIKGKVCSLAVCAVAWLVAHVRMLGLDEREKSLQMIRQLAGPLFSENTLQFYN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SIQKITDNIKGKVCSLAVCAVAWLVAHVRMLGLDEREKSLQMIRQLAGPLFSENTLQFYN
              610       620       630       640       650       660

              670       680       690       700       710       720
pF1KA0 ERVVIMNSILERMCADVLQQTATQIKFPSTGVDTMPYWNLLPPKRPIKEVLTDIFAKVLE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ERVVIMNSILERMCADVLQQTATQIKFPSTGVDTMPYWNLLPPKRPIKEVLTDIFAKVLE
              670       680       690       700       710       720

              730       740       750       760       770       780
pF1KA0 KGWVDSRSIHIFDTLLHMGGVYWFCNNLIKELLKETRKEHTLRAVELLYSIFCLDMQQVT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KGWVDSRSIHIFDTLLHMGGVYWFCNNLIKELLKETRKEHTLRAVELLYSIFCLDMQQVT
              730       740       750       760       770       780

              790       800       810       820       830       840
pF1KA0 LVLLGHILPGLLTDSSKWHSLMDPPGTALAKLAVWCALSSYSSHKGQASTRQKKRHREDI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LVLLGHILPGLLTDSSKWHSLMDPPGTALAKLAVWCALSSYSSHKGQASTRQKKRHREDI
              790       800       810       820       830       840

              850       860       870       880       890       900
pF1KA0 EDYISLFPLDDVQPSKLMRLLSSNEDDANILSSPTDRSMSSSLSASQLHTVNMRDPLNRV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EDYISLFPLDDVQPSKLMRLLSSNEDDANILSSPTDRSMSSSLSASQLHTVNMRDPLNRV
              850       860       870       880       890       900

              910       920       930       940       950       960
pF1KA0 LANLFLLISSILGSRTAGPHTQFVQWFMEECVDCLEQGGRGSVLQFMPFTTVSELVKVSA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LANLFLLISSILGSRTAGPHTQFVQWFMEECVDCLEQGGRGSVLQFMPFTTVSELVKVSA
              910       920       930       940       950       960

              970       980         
pF1KA0 MSSPKVVLAITDLSLPLGRQVAAKAIAAL
       :::::::::::::::::::::::::::::
XP_016 MSSPKVVLAITDLSLPLGRQVAAKAIAAL
              970       980         

>>XP_005257931 (OMIM: 607000) PREDICTED: mediator of RNA  (1014 aa)
 initn: 6481 init1: 6481 opt: 6481  Z-score: 7526.4  bits: 1404.1 E(85289):    0
Smith-Waterman score: 6481; 99.8% identity (99.9% similar) in 989 aa overlap (1-989:26-1014)

                                        10        20        30     
pF1KA0                          MKVVNLKQAILQAWKERWSYYQWAINMKKFFPKGA
                                ::::::::::::::::::: :::::::::::::::
XP_005 MSFSLAPFLSPQSWPPPLPPAQSEIMKVVNLKQAILQAWKERWSDYQWAINMKKFFPKGA
               10        20        30        40        50        60

          40        50        60        70        80        90     
pF1KA0 TWDILNLADALLEQAMIGPSPNPLILSYLKYAISSQMVSYSSVLTAISKFDDFSRDLCVQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TWDILNLADALLEQAMIGPSPNPLILSYLKYAISSQMVSYSSVLTAISKFDDFSRDLCVQ
               70        80        90       100       110       120

         100       110       120       130       140       150     
pF1KA0 ALLDIMDMFCDRLSCHGKAEECIGLCRALLSALHWLLRCTAASAERLREGLEAGTPAAGE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ALLDIMDMFCDRLSCHGKAEECIGLCRALLSALHWLLRCTAASAERLREGLEAGTPAAGE
              130       140       150       160       170       180

         160       170       180       190       200       210     
pF1KA0 KQLAMCLQRLEKTLSSTKNRALLHIAKLEEASSWTAIEHSLLKLGEILTNLSNPQLRSQA
       ::::::::::::::::::::::::::::::::::::::::::::::::.:::::::::::
XP_005 KQLAMCLQRLEKTLSSTKNRALLHIAKLEEASSWTAIEHSLLKLGEILANLSNPQLRSQA
              190       200       210       220       230       240

         220       230       240       250       260       270     
pF1KA0 EQCGTLIRSIPTMLSVHAEQMHKTGFPTVHAVILLEGTMNLTGETQSLVEQLTMVKRMQH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EQCGTLIRSIPTMLSVHAEQMHKTGFPTVHAVILLEGTMNLTGETQSLVEQLTMVKRMQH
              250       260       270       280       290       300

         280       290       300       310       320       330     
pF1KA0 IPTPLFVLEIWKACFVGLIESPEGTEELKWTAFTFLKIPQVLVKLKKYSHGDKDFTEDVN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 IPTPLFVLEIWKACFVGLIESPEGTEELKWTAFTFLKIPQVLVKLKKYSHGDKDFTEDVN
              310       320       330       340       350       360

         340       350       360       370       380       390     
pF1KA0 CAFEFLLKLTPLLDKADQRCNCDCTNFLLQECGKQGLLSEASVNNLMAKRKADREHAPQQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 CAFEFLLKLTPLLDKADQRCNCDCTNFLLQECGKQGLLSEASVNNLMAKRKADREHAPQQ
              370       380       390       400       410       420

         400       410       420       430       440       450     
pF1KA0 KSGENANIQPNIQLILRAEPTVTNILKTMDADHSKSPEGLLGVLGHMLSGKSLDLLLAAA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KSGENANIQPNIQLILRAEPTVTNILKTMDADHSKSPEGLLGVLGHMLSGKSLDLLLAAA
              430       440       450       460       470       480

         460       470       480       490       500       510     
pF1KA0 AATGKLKSFARKFINLNEFTTYGSEESTKPASVRALLFDISFLMLCHVAQTYGSEVILSE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 AATGKLKSFARKFINLNEFTTYGSEESTKPASVRALLFDISFLMLCHVAQTYGSEVILSE
              490       500       510       520       530       540

         520       530       540       550       560       570     
pF1KA0 SRTGAEVPFFETWMQTCMPEEGKILNPDHPCFRPDSTKVESLVALLNNSSEMKLVQMKWH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SRTGAEVPFFETWMQTCMPEEGKILNPDHPCFRPDSTKVESLVALLNNSSEMKLVQMKWH
              550       560       570       580       590       600

         580       590       600       610       620       630     
pF1KA0 EACLSISAAILEILNAWENGVLAFESIQKITDNIKGKVCSLAVCAVAWLVAHVRMLGLDE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EACLSISAAILEILNAWENGVLAFESIQKITDNIKGKVCSLAVCAVAWLVAHVRMLGLDE
              610       620       630       640       650       660

         640       650       660       670       680       690     
pF1KA0 REKSLQMIRQLAGPLFSENTLQFYNERVVIMNSILERMCADVLQQTATQIKFPSTGVDTM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 REKSLQMIRQLAGPLFSENTLQFYNERVVIMNSILERMCADVLQQTATQIKFPSTGVDTM
              670       680       690       700       710       720

         700       710       720       730       740       750     
pF1KA0 PYWNLLPPKRPIKEVLTDIFAKVLEKGWVDSRSIHIFDTLLHMGGVYWFCNNLIKELLKE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PYWNLLPPKRPIKEVLTDIFAKVLEKGWVDSRSIHIFDTLLHMGGVYWFCNNLIKELLKE
              730       740       750       760       770       780

         760       770       780       790       800       810     
pF1KA0 TRKEHTLRAVELLYSIFCLDMQQVTLVLLGHILPGLLTDSSKWHSLMDPPGTALAKLAVW
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TRKEHTLRAVELLYSIFCLDMQQVTLVLLGHILPGLLTDSSKWHSLMDPPGTALAKLAVW
              790       800       810       820       830       840

         820       830       840       850       860       870     
pF1KA0 CALSSYSSHKGQASTRQKKRHREDIEDYISLFPLDDVQPSKLMRLLSSNEDDANILSSPT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 CALSSYSSHKGQASTRQKKRHREDIEDYISLFPLDDVQPSKLMRLLSSNEDDANILSSPT
              850       860       870       880       890       900

         880       890       900       910       920       930     
pF1KA0 DRSMSSSLSASQLHTVNMRDPLNRVLANLFLLISSILGSRTAGPHTQFVQWFMEECVDCL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DRSMSSSLSASQLHTVNMRDPLNRVLANLFLLISSILGSRTAGPHTQFVQWFMEECVDCL
              910       920       930       940       950       960

         940       950       960       970       980         
pF1KA0 EQGGRGSVLQFMPFTTVSELVKVSAMSSPKVVLAITDLSLPLGRQVAAKAIAAL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EQGGRGSVLQFMPFTTVSELVKVSAMSSPKVVLAITDLSLPLGRQVAAKAIAAL
              970       980       990      1000      1010    

>>XP_016880956 (OMIM: 607000) PREDICTED: mediator of RNA  (988 aa)
 initn: 5756 init1: 5756 opt: 6458  Z-score: 7499.9  bits: 1399.2 E(85289):    0
Smith-Waterman score: 6458; 99.6% identity (99.8% similar) in 989 aa overlap (1-989:1-988)

               10        20        30        40        50        60
pF1KA0 MKVVNLKQAILQAWKERWSYYQWAINMKKFFPKGATWDILNLADALLEQAMIGPSPNPLI
       ::::::::::::::::::: ::::::::::::::::::::::::::::::::::::::::
XP_016 MKVVNLKQAILQAWKERWSDYQWAINMKKFFPKGATWDILNLADALLEQAMIGPSPNPLI
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KA0 LSYLKYAISSQMVSYSSVLTAISKFDDFSRDLCVQALLDIMDMFCDRLSCHGKAEECIGL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LSYLKYAISSQMVSYSSVLTAISKFDDFSRDLCVQALLDIMDMFCDRLSCHGKAEECIGL
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KA0 CRALLSALHWLLRCTAASAERLREGLEAGTPAAGEKQLAMCLQRLEKTLSSTKNRALLHI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CRALLSALHWLLRCTAASAERLREGLEAGTPAAGEKQLAMCLQRLEKTLSSTKNRALLHI
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KA0 AKLEEASSWTAIEHSLLKLGEILTNLSNPQLRSQAEQCGTLIRSIPTMLSVHAEQMHKTG
       :::::::::::::::::::::::.::::::::::::::::::::::::::::::::::::
XP_016 AKLEEASSWTAIEHSLLKLGEILANLSNPQLRSQAEQCGTLIRSIPTMLSVHAEQMHKTG
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KA0 FPTVHAVILLEGTMNLTGETQSLVEQLTMVKRMQHIPTPLFVLEIWKACFVGLIESPEGT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FPTVHAVILLEGTMNLTGETQSLVEQLTMVKRMQHIPTPLFVLEIWKACFVGLIESPEGT
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KA0 EELKWTAFTFLKIPQVLVKLKKYSHGDKDFTEDVNCAFEFLLKLTPLLDKADQRCNCDCT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EELKWTAFTFLKIPQVLVKLKKYSHGDKDFTEDVNCAFEFLLKLTPLLDKADQRCNCDCT
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KA0 NFLLQECGKQGLLSEASVNNLMAKRKADREHAPQQKSGENANIQPNIQLILRAEPTVTNI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NFLLQECGKQGLLSEASVNNLMAKRKADREHAPQQKSGENANIQPNIQLILRAEPTVTNI
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KA0 LKTMDADHSKSPEGLLGVLGHMLSGKSLDLLLAAAAATGKLKSFARKFINLNEFTTYGSE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LKTMDADHSKSPEGLLGVLGHMLSGKSLDLLLAAAAATGKLKSFARKFINLNEFTTYGSE
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KA0 ESTKPASVRALLFDISFLMLCHVAQTYGSEVILSESRTGAEVPFFETWMQTCMPEEGKIL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ESTKPASVRALLFDISFLMLCHVAQTYGSEVILSESRTGAEVPFFETWMQTCMPEEGKIL
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KA0 NPDHPCFRPDSTKVESLVALLNNSSEMKLVQMKWHEACLSISAAILEILNAWENGVLAFE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NPDHPCFRPDSTKVESLVALLNNSSEMKLVQMKWHEACLSISAAILEILNAWENGVLAFE
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KA0 SIQKITDNIKGKVCSLAVCAVAWLVAHVRMLGLDEREKSLQMIRQLAGPLFSENTLQFYN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SIQKITDNIKGKVCSLAVCAVAWLVAHVRMLGLDEREKSLQMIRQLAGPLFSENTLQFYN
              610       620       630       640       650       660

              670       680       690       700       710       720
pF1KA0 ERVVIMNSILERMCADVLQQTATQIKFPSTGVDTMPYWNLLPPKRPIKEVLTDIFAKVLE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ERVVIMNSILERMCADVLQQTATQIKFPSTGVDTMPYWNLLPPKRPIKEVLTDIFAKVLE
              670       680       690       700       710       720

              730       740       750       760       770       780
pF1KA0 KGWVDSRSIHIFDTLLHMGGVYWFCNNLIKELLKETRKEHTLRAVELLYSIFCLDMQQVT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KGWVDSRSIHIFDTLLHMGGVYWFCNNLIKELLKETRKEHTLRAVELLYSIFCLDMQQVT
              730       740       750       760       770       780

              790       800       810       820       830       840
pF1KA0 LVLLGHILPGLLTDSSKWHSLMDPPGTALAKLAVWCALSSYSSHKGQASTRQKKRHREDI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LVLLGHILPGLLTDSSKWHSLMDPPGTALAKLAVWCALSSYSSHKGQASTRQKKRHREDI
              790       800       810       820       830       840

              850       860       870       880       890       900
pF1KA0 EDYISLFPLDDVQPSKLMRLLSSNEDDANILSSPTDRSMSSSLSASQLHTVNMRDPLNRV
       :::::::::::::::::::::::::::::::::: .::::::::::::::::::::::::
XP_016 EDYISLFPLDDVQPSKLMRLLSSNEDDANILSSP-NRSMSSSLSASQLHTVNMRDPLNRV
              850       860       870        880       890         

              910       920       930       940       950       960
pF1KA0 LANLFLLISSILGSRTAGPHTQFVQWFMEECVDCLEQGGRGSVLQFMPFTTVSELVKVSA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LANLFLLISSILGSRTAGPHTQFVQWFMEECVDCLEQGGRGSVLQFMPFTTVSELVKVSA
     900       910       920       930       940       950         

              970       980         
pF1KA0 MSSPKVVLAITDLSLPLGRQVAAKAIAAL
       :::::::::::::::::::::::::::::
XP_016 MSSPKVVLAITDLSLPLGRQVAAKAIAAL
     960       970       980        

>>XP_016880957 (OMIM: 607000) PREDICTED: mediator of RNA  (988 aa)
 initn: 5756 init1: 5756 opt: 6458  Z-score: 7499.9  bits: 1399.2 E(85289):    0
Smith-Waterman score: 6458; 99.6% identity (99.8% similar) in 989 aa overlap (1-989:1-988)

               10        20        30        40        50        60
pF1KA0 MKVVNLKQAILQAWKERWSYYQWAINMKKFFPKGATWDILNLADALLEQAMIGPSPNPLI
       ::::::::::::::::::: ::::::::::::::::::::::::::::::::::::::::
XP_016 MKVVNLKQAILQAWKERWSDYQWAINMKKFFPKGATWDILNLADALLEQAMIGPSPNPLI
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KA0 LSYLKYAISSQMVSYSSVLTAISKFDDFSRDLCVQALLDIMDMFCDRLSCHGKAEECIGL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LSYLKYAISSQMVSYSSVLTAISKFDDFSRDLCVQALLDIMDMFCDRLSCHGKAEECIGL
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KA0 CRALLSALHWLLRCTAASAERLREGLEAGTPAAGEKQLAMCLQRLEKTLSSTKNRALLHI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CRALLSALHWLLRCTAASAERLREGLEAGTPAAGEKQLAMCLQRLEKTLSSTKNRALLHI
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KA0 AKLEEASSWTAIEHSLLKLGEILTNLSNPQLRSQAEQCGTLIRSIPTMLSVHAEQMHKTG
       :::::::::::::::::::::::.::::::::::::::::::::::::::::::::::::
XP_016 AKLEEASSWTAIEHSLLKLGEILANLSNPQLRSQAEQCGTLIRSIPTMLSVHAEQMHKTG
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KA0 FPTVHAVILLEGTMNLTGETQSLVEQLTMVKRMQHIPTPLFVLEIWKACFVGLIESPEGT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FPTVHAVILLEGTMNLTGETQSLVEQLTMVKRMQHIPTPLFVLEIWKACFVGLIESPEGT
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KA0 EELKWTAFTFLKIPQVLVKLKKYSHGDKDFTEDVNCAFEFLLKLTPLLDKADQRCNCDCT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EELKWTAFTFLKIPQVLVKLKKYSHGDKDFTEDVNCAFEFLLKLTPLLDKADQRCNCDCT
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KA0 NFLLQECGKQGLLSEASVNNLMAKRKADREHAPQQKSGENANIQPNIQLILRAEPTVTNI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NFLLQECGKQGLLSEASVNNLMAKRKADREHAPQQKSGENANIQPNIQLILRAEPTVTNI
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KA0 LKTMDADHSKSPEGLLGVLGHMLSGKSLDLLLAAAAATGKLKSFARKFINLNEFTTYGSE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LKTMDADHSKSPEGLLGVLGHMLSGKSLDLLLAAAAATGKLKSFARKFINLNEFTTYGSE
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KA0 ESTKPASVRALLFDISFLMLCHVAQTYGSEVILSESRTGAEVPFFETWMQTCMPEEGKIL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ESTKPASVRALLFDISFLMLCHVAQTYGSEVILSESRTGAEVPFFETWMQTCMPEEGKIL
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KA0 NPDHPCFRPDSTKVESLVALLNNSSEMKLVQMKWHEACLSISAAILEILNAWENGVLAFE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NPDHPCFRPDSTKVESLVALLNNSSEMKLVQMKWHEACLSISAAILEILNAWENGVLAFE
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KA0 SIQKITDNIKGKVCSLAVCAVAWLVAHVRMLGLDEREKSLQMIRQLAGPLFSENTLQFYN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SIQKITDNIKGKVCSLAVCAVAWLVAHVRMLGLDEREKSLQMIRQLAGPLFSENTLQFYN
              610       620       630       640       650       660

              670       680       690       700       710       720
pF1KA0 ERVVIMNSILERMCADVLQQTATQIKFPSTGVDTMPYWNLLPPKRPIKEVLTDIFAKVLE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ERVVIMNSILERMCADVLQQTATQIKFPSTGVDTMPYWNLLPPKRPIKEVLTDIFAKVLE
              670       680       690       700       710       720

              730       740       750       760       770       780
pF1KA0 KGWVDSRSIHIFDTLLHMGGVYWFCNNLIKELLKETRKEHTLRAVELLYSIFCLDMQQVT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KGWVDSRSIHIFDTLLHMGGVYWFCNNLIKELLKETRKEHTLRAVELLYSIFCLDMQQVT
              730       740       750       760       770       780

              790       800       810       820       830       840
pF1KA0 LVLLGHILPGLLTDSSKWHSLMDPPGTALAKLAVWCALSSYSSHKGQASTRQKKRHREDI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LVLLGHILPGLLTDSSKWHSLMDPPGTALAKLAVWCALSSYSSHKGQASTRQKKRHREDI
              790       800       810       820       830       840

              850       860       870       880       890       900
pF1KA0 EDYISLFPLDDVQPSKLMRLLSSNEDDANILSSPTDRSMSSSLSASQLHTVNMRDPLNRV
       :::::::::::::::::::::::::::::::::: .::::::::::::::::::::::::
XP_016 EDYISLFPLDDVQPSKLMRLLSSNEDDANILSSP-NRSMSSSLSASQLHTVNMRDPLNRV
              850       860       870        880       890         

              910       920       930       940       950       960
pF1KA0 LANLFLLISSILGSRTAGPHTQFVQWFMEECVDCLEQGGRGSVLQFMPFTTVSELVKVSA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LANLFLLISSILGSRTAGPHTQFVQWFMEECVDCLEQGGRGSVLQFMPFTTVSELVKVSA
     900       910       920       930       940       950         

              970       980         
pF1KA0 MSSPKVVLAITDLSLPLGRQVAAKAIAAL
       :::::::::::::::::::::::::::::
XP_016 MSSPKVVLAITDLSLPLGRQVAAKAIAAL
     960       970       980        

>>NP_001254726 (OMIM: 607000) mediator of RNA polymerase  (976 aa)
 initn: 5948 init1: 5948 opt: 5948  Z-score: 6907.2  bits: 1289.5 E(85289):    0
Smith-Waterman score: 6374; 98.5% identity (98.6% similar) in 989 aa overlap (1-989:1-976)

               10        20        30        40        50        60
pF1KA0 MKVVNLKQAILQAWKERWSYYQWAINMKKFFPKGATWDILNLADALLEQAMIGPSPNPLI
       ::::::::::::::::::: ::::::::::::::::::::::::::::::::::::::::
NP_001 MKVVNLKQAILQAWKERWSDYQWAINMKKFFPKGATWDILNLADALLEQAMIGPSPNPLI
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KA0 LSYLKYAISSQMVSYSSVLTAISKFDDFSRDLCVQALLDIMDMFCDRLSCHGKAEECIGL
       :::::::::::             ::::::::::::::::::::::::::::::::::::
NP_001 LSYLKYAISSQ-------------FDDFSRDLCVQALLDIMDMFCDRLSCHGKAEECIGL
               70                     80        90       100       

              130       140       150       160       170       180
pF1KA0 CRALLSALHWLLRCTAASAERLREGLEAGTPAAGEKQLAMCLQRLEKTLSSTKNRALLHI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CRALLSALHWLLRCTAASAERLREGLEAGTPAAGEKQLAMCLQRLEKTLSSTKNRALLHI
       110       120       130       140       150       160       

              190       200       210       220       230       240
pF1KA0 AKLEEASSWTAIEHSLLKLGEILTNLSNPQLRSQAEQCGTLIRSIPTMLSVHAEQMHKTG
       :::::::::::::::::::::::.::::::::::::::::::::::::::::::::::::
NP_001 AKLEEASSWTAIEHSLLKLGEILANLSNPQLRSQAEQCGTLIRSIPTMLSVHAEQMHKTG
       170       180       190       200       210       220       

              250       260       270       280       290       300
pF1KA0 FPTVHAVILLEGTMNLTGETQSLVEQLTMVKRMQHIPTPLFVLEIWKACFVGLIESPEGT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FPTVHAVILLEGTMNLTGETQSLVEQLTMVKRMQHIPTPLFVLEIWKACFVGLIESPEGT
       230       240       250       260       270       280       

              310       320       330       340       350       360
pF1KA0 EELKWTAFTFLKIPQVLVKLKKYSHGDKDFTEDVNCAFEFLLKLTPLLDKADQRCNCDCT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EELKWTAFTFLKIPQVLVKLKKYSHGDKDFTEDVNCAFEFLLKLTPLLDKADQRCNCDCT
       290       300       310       320       330       340       

              370       380       390       400       410       420
pF1KA0 NFLLQECGKQGLLSEASVNNLMAKRKADREHAPQQKSGENANIQPNIQLILRAEPTVTNI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NFLLQECGKQGLLSEASVNNLMAKRKADREHAPQQKSGENANIQPNIQLILRAEPTVTNI
       350       360       370       380       390       400       

              430       440       450       460       470       480
pF1KA0 LKTMDADHSKSPEGLLGVLGHMLSGKSLDLLLAAAAATGKLKSFARKFINLNEFTTYGSE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LKTMDADHSKSPEGLLGVLGHMLSGKSLDLLLAAAAATGKLKSFARKFINLNEFTTYGSE
       410       420       430       440       450       460       

              490       500       510       520       530       540
pF1KA0 ESTKPASVRALLFDISFLMLCHVAQTYGSEVILSESRTGAEVPFFETWMQTCMPEEGKIL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ESTKPASVRALLFDISFLMLCHVAQTYGSEVILSESRTGAEVPFFETWMQTCMPEEGKIL
       470       480       490       500       510       520       

              550       560       570       580       590       600
pF1KA0 NPDHPCFRPDSTKVESLVALLNNSSEMKLVQMKWHEACLSISAAILEILNAWENGVLAFE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NPDHPCFRPDSTKVESLVALLNNSSEMKLVQMKWHEACLSISAAILEILNAWENGVLAFE
       530       540       550       560       570       580       

              610       620       630       640       650       660
pF1KA0 SIQKITDNIKGKVCSLAVCAVAWLVAHVRMLGLDEREKSLQMIRQLAGPLFSENTLQFYN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SIQKITDNIKGKVCSLAVCAVAWLVAHVRMLGLDEREKSLQMIRQLAGPLFSENTLQFYN
       590       600       610       620       630       640       

              670       680       690       700       710       720
pF1KA0 ERVVIMNSILERMCADVLQQTATQIKFPSTGVDTMPYWNLLPPKRPIKEVLTDIFAKVLE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ERVVIMNSILERMCADVLQQTATQIKFPSTGVDTMPYWNLLPPKRPIKEVLTDIFAKVLE
       650       660       670       680       690       700       

              730       740       750       760       770       780
pF1KA0 KGWVDSRSIHIFDTLLHMGGVYWFCNNLIKELLKETRKEHTLRAVELLYSIFCLDMQQVT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KGWVDSRSIHIFDTLLHMGGVYWFCNNLIKELLKETRKEHTLRAVELLYSIFCLDMQQVT
       710       720       730       740       750       760       

              790       800       810       820       830       840
pF1KA0 LVLLGHILPGLLTDSSKWHSLMDPPGTALAKLAVWCALSSYSSHKGQASTRQKKRHREDI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LVLLGHILPGLLTDSSKWHSLMDPPGTALAKLAVWCALSSYSSHKGQASTRQKKRHREDI
       770       780       790       800       810       820       

              850       860       870       880       890       900
pF1KA0 EDYISLFPLDDVQPSKLMRLLSSNEDDANILSSPTDRSMSSSLSASQLHTVNMRDPLNRV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EDYISLFPLDDVQPSKLMRLLSSNEDDANILSSPTDRSMSSSLSASQLHTVNMRDPLNRV
       830       840       850       860       870       880       

              910       920       930       940       950       960
pF1KA0 LANLFLLISSILGSRTAGPHTQFVQWFMEECVDCLEQGGRGSVLQFMPFTTVSELVKVSA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LANLFLLISSILGSRTAGPHTQFVQWFMEECVDCLEQGGRGSVLQFMPFTTVSELVKVSA
       890       900       910       920       930       940       

              970       980         
pF1KA0 MSSPKVVLAITDLSLPLGRQVAAKAIAAL
       :::::::::::::::::::::::::::::
NP_001 MSSPKVVLAITDLSLPLGRQVAAKAIAAL
       950       960       970      

>>NP_001072986 (OMIM: 607000) mediator of RNA polymerase  (976 aa)
 initn: 5948 init1: 5948 opt: 5948  Z-score: 6907.2  bits: 1289.5 E(85289):    0
Smith-Waterman score: 6374; 98.5% identity (98.6% similar) in 989 aa overlap (1-989:1-976)

               10        20        30        40        50        60
pF1KA0 MKVVNLKQAILQAWKERWSYYQWAINMKKFFPKGATWDILNLADALLEQAMIGPSPNPLI
       ::::::::::::::::::: ::::::::::::::::::::::::::::::::::::::::
NP_001 MKVVNLKQAILQAWKERWSDYQWAINMKKFFPKGATWDILNLADALLEQAMIGPSPNPLI
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KA0 LSYLKYAISSQMVSYSSVLTAISKFDDFSRDLCVQALLDIMDMFCDRLSCHGKAEECIGL
       :::::::::::             ::::::::::::::::::::::::::::::::::::
NP_001 LSYLKYAISSQ-------------FDDFSRDLCVQALLDIMDMFCDRLSCHGKAEECIGL
               70                     80        90       100       

              130       140       150       160       170       180
pF1KA0 CRALLSALHWLLRCTAASAERLREGLEAGTPAAGEKQLAMCLQRLEKTLSSTKNRALLHI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CRALLSALHWLLRCTAASAERLREGLEAGTPAAGEKQLAMCLQRLEKTLSSTKNRALLHI
       110       120       130       140       150       160       

              190       200       210       220       230       240
pF1KA0 AKLEEASSWTAIEHSLLKLGEILTNLSNPQLRSQAEQCGTLIRSIPTMLSVHAEQMHKTG
       :::::::::::::::::::::::.::::::::::::::::::::::::::::::::::::
NP_001 AKLEEASSWTAIEHSLLKLGEILANLSNPQLRSQAEQCGTLIRSIPTMLSVHAEQMHKTG
       170       180       190       200       210       220       

              250       260       270       280       290       300
pF1KA0 FPTVHAVILLEGTMNLTGETQSLVEQLTMVKRMQHIPTPLFVLEIWKACFVGLIESPEGT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FPTVHAVILLEGTMNLTGETQSLVEQLTMVKRMQHIPTPLFVLEIWKACFVGLIESPEGT
       230       240       250       260       270       280       

              310       320       330       340       350       360
pF1KA0 EELKWTAFTFLKIPQVLVKLKKYSHGDKDFTEDVNCAFEFLLKLTPLLDKADQRCNCDCT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EELKWTAFTFLKIPQVLVKLKKYSHGDKDFTEDVNCAFEFLLKLTPLLDKADQRCNCDCT
       290       300       310       320       330       340       

              370       380       390       400       410       420
pF1KA0 NFLLQECGKQGLLSEASVNNLMAKRKADREHAPQQKSGENANIQPNIQLILRAEPTVTNI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NFLLQECGKQGLLSEASVNNLMAKRKADREHAPQQKSGENANIQPNIQLILRAEPTVTNI
       350       360       370       380       390       400       

              430       440       450       460       470       480
pF1KA0 LKTMDADHSKSPEGLLGVLGHMLSGKSLDLLLAAAAATGKLKSFARKFINLNEFTTYGSE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LKTMDADHSKSPEGLLGVLGHMLSGKSLDLLLAAAAATGKLKSFARKFINLNEFTTYGSE
       410       420       430       440       450       460       

              490       500       510       520       530       540
pF1KA0 ESTKPASVRALLFDISFLMLCHVAQTYGSEVILSESRTGAEVPFFETWMQTCMPEEGKIL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ESTKPASVRALLFDISFLMLCHVAQTYGSEVILSESRTGAEVPFFETWMQTCMPEEGKIL
       470       480       490       500       510       520       

              550       560       570       580       590       600
pF1KA0 NPDHPCFRPDSTKVESLVALLNNSSEMKLVQMKWHEACLSISAAILEILNAWENGVLAFE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NPDHPCFRPDSTKVESLVALLNNSSEMKLVQMKWHEACLSISAAILEILNAWENGVLAFE
       530       540       550       560       570       580       

              610       620       630       640       650       660
pF1KA0 SIQKITDNIKGKVCSLAVCAVAWLVAHVRMLGLDEREKSLQMIRQLAGPLFSENTLQFYN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SIQKITDNIKGKVCSLAVCAVAWLVAHVRMLGLDEREKSLQMIRQLAGPLFSENTLQFYN
       590       600       610       620       630       640       

              670       680       690       700       710       720
pF1KA0 ERVVIMNSILERMCADVLQQTATQIKFPSTGVDTMPYWNLLPPKRPIKEVLTDIFAKVLE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ERVVIMNSILERMCADVLQQTATQIKFPSTGVDTMPYWNLLPPKRPIKEVLTDIFAKVLE
       650       660       670       680       690       700       

              730       740       750       760       770       780
pF1KA0 KGWVDSRSIHIFDTLLHMGGVYWFCNNLIKELLKETRKEHTLRAVELLYSIFCLDMQQVT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KGWVDSRSIHIFDTLLHMGGVYWFCNNLIKELLKETRKEHTLRAVELLYSIFCLDMQQVT
       710       720       730       740       750       760       

              790       800       810       820       830       840
pF1KA0 LVLLGHILPGLLTDSSKWHSLMDPPGTALAKLAVWCALSSYSSHKGQASTRQKKRHREDI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LVLLGHILPGLLTDSSKWHSLMDPPGTALAKLAVWCALSSYSSHKGQASTRQKKRHREDI
       770       780       790       800       810       820       

              850       860       870       880       890       900
pF1KA0 EDYISLFPLDDVQPSKLMRLLSSNEDDANILSSPTDRSMSSSLSASQLHTVNMRDPLNRV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EDYISLFPLDDVQPSKLMRLLSSNEDDANILSSPTDRSMSSSLSASQLHTVNMRDPLNRV
       830       840       850       860       870       880       

              910       920       930       940       950       960
pF1KA0 LANLFLLISSILGSRTAGPHTQFVQWFMEECVDCLEQGGRGSVLQFMPFTTVSELVKVSA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LANLFLLISSILGSRTAGPHTQFVQWFMEECVDCLEQGGRGSVLQFMPFTTVSELVKVSA
       890       900       910       920       930       940       

              970       980         
pF1KA0 MSSPKVVLAITDLSLPLGRQVAAKAIAAL
       :::::::::::::::::::::::::::::
NP_001 MSSPKVVLAITDLSLPLGRQVAAKAIAAL
       950       960       970      

>>XP_016880948 (OMIM: 607000) PREDICTED: mediator of RNA  (1032 aa)
 initn: 5755 init1: 5755 opt: 5758  Z-score: 6686.0  bits: 1248.7 E(85289):    0
Smith-Waterman score: 6320; 95.5% identity (95.7% similar) in 1021 aa overlap (1-978:1-1021)

               10        20        30        40        50        60
pF1KA0 MKVVNLKQAILQAWKERWSYYQWAINMKKFFPKGATWDILNLADALLEQAMIGPSPNPLI
       ::::::::::::::::::: ::::::::::::::::::::::::::::::::::::::::
XP_016 MKVVNLKQAILQAWKERWSDYQWAINMKKFFPKGATWDILNLADALLEQAMIGPSPNPLI
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KA0 LSYLKYAISSQMVSYSSVLTAISKFDDFSRDLCVQALLDIMDMFCDRLSCHGKAEECIGL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LSYLKYAISSQMVSYSSVLTAISKFDDFSRDLCVQALLDIMDMFCDRLSCHGKAEECIGL
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KA0 CRALLSALHWLLRCTAASAERLREGLEAGTPAAGEKQLAMCLQRLEKTLSSTKNRALLHI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CRALLSALHWLLRCTAASAERLREGLEAGTPAAGEKQLAMCLQRLEKTLSSTKNRALLHI
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KA0 AKLEEASSWTAIEHSLLKLGEILTNLSNPQLRSQAEQCGTLIRSIPTMLSVHAEQMHKTG
       :::::::::::::::::::::::.::::::::::::::::::::::::::::::::::::
XP_016 AKLEEASSWTAIEHSLLKLGEILANLSNPQLRSQAEQCGTLIRSIPTMLSVHAEQMHKTG
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KA0 FPTVHAVILLEGTMNLTGETQSLVEQLTMVKRMQHIPTPLFVLEIWKACFVGLIESPEGT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FPTVHAVILLEGTMNLTGETQSLVEQLTMVKRMQHIPTPLFVLEIWKACFVGLIESPEGT
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KA0 EELKWTAFTFLKIPQVLVKLKKYSHGDKDFTEDVNCAFEFLLKLTPLLDKADQRCNCDCT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EELKWTAFTFLKIPQVLVKLKKYSHGDKDFTEDVNCAFEFLLKLTPLLDKADQRCNCDCT
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KA0 NFLLQECGKQGLLSEASVNNLMAKRKADREHAPQQKSGENANIQPNIQLILRAEPTVTNI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NFLLQECGKQGLLSEASVNNLMAKRKADREHAPQQKSGENANIQPNIQLILRAEPTVTNI
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KA0 LKTMDADHSKSPEGLLGVLGHMLSGKSLDLLLAAAAATGKLKSFARKFINLNEFTTYGSE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LKTMDADHSKSPEGLLGVLGHMLSGKSLDLLLAAAAATGKLKSFARKFINLNEFTTYGSE
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KA0 ESTKPASVRALLFDISFLMLCHVAQTYGSEVILSESRTGAEVPFFETWMQTCMPEEGKIL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ESTKPASVRALLFDISFLMLCHVAQTYGSEVILSESRTGAEVPFFETWMQTCMPEEGKIL
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KA0 NPDHPCFRPDSTKVESLVALLNNSSEMKLVQMKWHEACLSISAAILEILNAWENGVLAFE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NPDHPCFRPDSTKVESLVALLNNSSEMKLVQMKWHEACLSISAAILEILNAWENGVLAFE
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KA0 SIQKITDNIKGKVCSLAVCAVAWLVAHVRMLGLDEREKSLQMIRQLAGPLFSENTLQFYN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SIQKITDNIKGKVCSLAVCAVAWLVAHVRMLGLDEREKSLQMIRQLAGPLFSENTLQFYN
              610       620       630       640       650       660

              670       680       690       700       710       720
pF1KA0 ERVVIMNSILERMCADVLQQTATQIKFPSTGVDTMPYWNLLPPKRPIKEVLTDIFAKVLE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ERVVIMNSILERMCADVLQQTATQIKFPSTGVDTMPYWNLLPPKRPIKEVLTDIFAKVLE
              670       680       690       700       710       720

              730       740       750       760       770       780
pF1KA0 KGWVDSRSIHIFDTLLHMGGVYWFCNNLIKELLKETRKEHTLRAVELLYSIFCLDMQQVT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KGWVDSRSIHIFDTLLHMGGVYWFCNNLIKELLKETRKEHTLRAVELLYSIFCLDMQQVT
              730       740       750       760       770       780

              790       800       810       820       830       840
pF1KA0 LVLLGHILPGLLTDSSKWHSLMDPPGTALAKLAVWCALSSYSSHKGQASTRQKKRHREDI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LVLLGHILPGLLTDSSKWHSLMDPPGTALAKLAVWCALSSYSSHKGQASTRQKKRHREDI
              790       800       810       820       830       840

              850       860       870                              
pF1KA0 EDYISLFPLDDVQPSKLMRLLSSNEDDANILSSP--------------------------
       ::::::::::::::::::::::::::::::::::                          
XP_016 EDYISLFPLDDVQPSKLMRLLSSNEDDANILSSPRSSLGSPCTSYLRWVKVGLGHPRGAP
              850       860       870       880       890       900

                           880       890       900       910       
pF1KA0 -----------------TDRSMSSSLSASQLHTVNMRDPLNRVLANLFLLISSILGSRTA
                        .::::::::::::::::::::::::::::::::::::::::::
XP_016 LLHSAGCFPALHLLRPTADRSMSSSLSASQLHTVNMRDPLNRVLANLFLLISSILGSRTA
              910       920       930       940       950       960

       920       930       940       950       960       970       
pF1KA0 GPHTQFVQWFMEECVDCLEQGGRGSVLQFMPFTTVSELVKVSAMSSPKVVLAITDLSLPL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GPHTQFVQWFMEECVDCLEQGGRGSVLQFMPFTTVSELVKVSAMSSPKVVLAITDLSLPL
              970       980       990      1000      1010      1020

       980         
pF1KA0 GRQVAAKAIAAL
       :           
XP_016 GRQVAAKAIAAL
             1030  

>>XP_011523833 (OMIM: 607000) PREDICTED: mediator of RNA  (1032 aa)
 initn: 5755 init1: 5755 opt: 5758  Z-score: 6686.0  bits: 1248.7 E(85289):    0
Smith-Waterman score: 6320; 95.5% identity (95.7% similar) in 1021 aa overlap (1-978:1-1021)

               10        20        30        40        50        60
pF1KA0 MKVVNLKQAILQAWKERWSYYQWAINMKKFFPKGATWDILNLADALLEQAMIGPSPNPLI
       ::::::::::::::::::: ::::::::::::::::::::::::::::::::::::::::
XP_011 MKVVNLKQAILQAWKERWSDYQWAINMKKFFPKGATWDILNLADALLEQAMIGPSPNPLI
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KA0 LSYLKYAISSQMVSYSSVLTAISKFDDFSRDLCVQALLDIMDMFCDRLSCHGKAEECIGL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LSYLKYAISSQMVSYSSVLTAISKFDDFSRDLCVQALLDIMDMFCDRLSCHGKAEECIGL
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KA0 CRALLSALHWLLRCTAASAERLREGLEAGTPAAGEKQLAMCLQRLEKTLSSTKNRALLHI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CRALLSALHWLLRCTAASAERLREGLEAGTPAAGEKQLAMCLQRLEKTLSSTKNRALLHI
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KA0 AKLEEASSWTAIEHSLLKLGEILTNLSNPQLRSQAEQCGTLIRSIPTMLSVHAEQMHKTG
       :::::::::::::::::::::::.::::::::::::::::::::::::::::::::::::
XP_011 AKLEEASSWTAIEHSLLKLGEILANLSNPQLRSQAEQCGTLIRSIPTMLSVHAEQMHKTG
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KA0 FPTVHAVILLEGTMNLTGETQSLVEQLTMVKRMQHIPTPLFVLEIWKACFVGLIESPEGT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FPTVHAVILLEGTMNLTGETQSLVEQLTMVKRMQHIPTPLFVLEIWKACFVGLIESPEGT
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KA0 EELKWTAFTFLKIPQVLVKLKKYSHGDKDFTEDVNCAFEFLLKLTPLLDKADQRCNCDCT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EELKWTAFTFLKIPQVLVKLKKYSHGDKDFTEDVNCAFEFLLKLTPLLDKADQRCNCDCT
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KA0 NFLLQECGKQGLLSEASVNNLMAKRKADREHAPQQKSGENANIQPNIQLILRAEPTVTNI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NFLLQECGKQGLLSEASVNNLMAKRKADREHAPQQKSGENANIQPNIQLILRAEPTVTNI
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KA0 LKTMDADHSKSPEGLLGVLGHMLSGKSLDLLLAAAAATGKLKSFARKFINLNEFTTYGSE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LKTMDADHSKSPEGLLGVLGHMLSGKSLDLLLAAAAATGKLKSFARKFINLNEFTTYGSE
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KA0 ESTKPASVRALLFDISFLMLCHVAQTYGSEVILSESRTGAEVPFFETWMQTCMPEEGKIL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ESTKPASVRALLFDISFLMLCHVAQTYGSEVILSESRTGAEVPFFETWMQTCMPEEGKIL
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KA0 NPDHPCFRPDSTKVESLVALLNNSSEMKLVQMKWHEACLSISAAILEILNAWENGVLAFE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NPDHPCFRPDSTKVESLVALLNNSSEMKLVQMKWHEACLSISAAILEILNAWENGVLAFE
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KA0 SIQKITDNIKGKVCSLAVCAVAWLVAHVRMLGLDEREKSLQMIRQLAGPLFSENTLQFYN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SIQKITDNIKGKVCSLAVCAVAWLVAHVRMLGLDEREKSLQMIRQLAGPLFSENTLQFYN
              610       620       630       640       650       660

              670       680       690       700       710       720
pF1KA0 ERVVIMNSILERMCADVLQQTATQIKFPSTGVDTMPYWNLLPPKRPIKEVLTDIFAKVLE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ERVVIMNSILERMCADVLQQTATQIKFPSTGVDTMPYWNLLPPKRPIKEVLTDIFAKVLE
              670       680       690       700       710       720

              730       740       750       760       770       780
pF1KA0 KGWVDSRSIHIFDTLLHMGGVYWFCNNLIKELLKETRKEHTLRAVELLYSIFCLDMQQVT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KGWVDSRSIHIFDTLLHMGGVYWFCNNLIKELLKETRKEHTLRAVELLYSIFCLDMQQVT
              730       740       750       760       770       780

              790       800       810       820       830       840
pF1KA0 LVLLGHILPGLLTDSSKWHSLMDPPGTALAKLAVWCALSSYSSHKGQASTRQKKRHREDI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LVLLGHILPGLLTDSSKWHSLMDPPGTALAKLAVWCALSSYSSHKGQASTRQKKRHREDI
              790       800       810       820       830       840

              850       860       870                              
pF1KA0 EDYISLFPLDDVQPSKLMRLLSSNEDDANILSSP--------------------------
       ::::::::::::::::::::::::::::::::::                          
XP_011 EDYISLFPLDDVQPSKLMRLLSSNEDDANILSSPRSSLGSPCTSYLRWVKVGLGHPRGAP
              850       860       870       880       890       900

                           880       890       900       910       
pF1KA0 -----------------TDRSMSSSLSASQLHTVNMRDPLNRVLANLFLLISSILGSRTA
                        .::::::::::::::::::::::::::::::::::::::::::
XP_011 LLHSAGCFPALHLLRPTADRSMSSSLSASQLHTVNMRDPLNRVLANLFLLISSILGSRTA
              910       920       930       940       950       960

       920       930       940       950       960       970       
pF1KA0 GPHTQFVQWFMEECVDCLEQGGRGSVLQFMPFTTVSELVKVSAMSSPKVVLAITDLSLPL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GPHTQFVQWFMEECVDCLEQGGRGSVLQFMPFTTVSELVKVSAMSSPKVVLAITDLSLPL
              970       980       990      1000      1010      1020

       980         
pF1KA0 GRQVAAKAIAAL
       :           
XP_011 GRQVAAKAIAAL
             1030  

>>NP_001317140 (OMIM: 607000) mediator of RNA polymerase  (1008 aa)
 initn: 5256 init1: 5256 opt: 5256  Z-score: 6102.8  bits: 1140.7 E(85289):    0
Smith-Waterman score: 6433; 97.9% identity (98.0% similar) in 1008 aa overlap (1-989:1-1008)

               10        20        30        40        50        60
pF1KA0 MKVVNLKQAILQAWKERWSYYQWAINMKKFFPKGATWDILNLADALLEQAMIGPSPNPLI
       ::::::::::::::::::: ::::::::::::::::::::::::::::::::::::::::
NP_001 MKVVNLKQAILQAWKERWSDYQWAINMKKFFPKGATWDILNLADALLEQAMIGPSPNPLI
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KA0 LSYLKYAISSQMVSYSSVLTAISKFDDFSRDLCVQALLDIMDMFCDRLSCHGKAEECIGL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LSYLKYAISSQMVSYSSVLTAISKFDDFSRDLCVQALLDIMDMFCDRLSCHGKAEECIGL
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KA0 CRALLSALHWLLRCTAASAERLREGLEAGTPAAGEKQLAMCLQRLEKTLSSTKNRALLHI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CRALLSALHWLLRCTAASAERLREGLEAGTPAAGEKQLAMCLQRLEKTLSSTKNRALLHI
              130       140       150       160       170       180

                                 190       200       210       220 
pF1KA0 AKLEEAS-------------------SWTAIEHSLLKLGEILTNLSNPQLRSQAEQCGTL
       :::::::                   ::::::::::::::::.:::::::::::::::::
NP_001 AKLEEASLHTSQGLGQGGTRANQPTASWTAIEHSLLKLGEILANLSNPQLRSQAEQCGTL
              190       200       210       220       230       240

             230       240       250       260       270       280 
pF1KA0 IRSIPTMLSVHAEQMHKTGFPTVHAVILLEGTMNLTGETQSLVEQLTMVKRMQHIPTPLF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IRSIPTMLSVHAEQMHKTGFPTVHAVILLEGTMNLTGETQSLVEQLTMVKRMQHIPTPLF
              250       260       270       280       290       300

             290       300       310       320       330       340 
pF1KA0 VLEIWKACFVGLIESPEGTEELKWTAFTFLKIPQVLVKLKKYSHGDKDFTEDVNCAFEFL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VLEIWKACFVGLIESPEGTEELKWTAFTFLKIPQVLVKLKKYSHGDKDFTEDVNCAFEFL
              310       320       330       340       350       360

             350       360       370       380       390       400 
pF1KA0 LKLTPLLDKADQRCNCDCTNFLLQECGKQGLLSEASVNNLMAKRKADREHAPQQKSGENA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LKLTPLLDKADQRCNCDCTNFLLQECGKQGLLSEASVNNLMAKRKADREHAPQQKSGENA
              370       380       390       400       410       420

             410       420       430       440       450       460 
pF1KA0 NIQPNIQLILRAEPTVTNILKTMDADHSKSPEGLLGVLGHMLSGKSLDLLLAAAAATGKL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NIQPNIQLILRAEPTVTNILKTMDADHSKSPEGLLGVLGHMLSGKSLDLLLAAAAATGKL
              430       440       450       460       470       480

             470       480       490       500       510       520 
pF1KA0 KSFARKFINLNEFTTYGSEESTKPASVRALLFDISFLMLCHVAQTYGSEVILSESRTGAE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KSFARKFINLNEFTTYGSEESTKPASVRALLFDISFLMLCHVAQTYGSEVILSESRTGAE
              490       500       510       520       530       540

             530       540       550       560       570       580 
pF1KA0 VPFFETWMQTCMPEEGKILNPDHPCFRPDSTKVESLVALLNNSSEMKLVQMKWHEACLSI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VPFFETWMQTCMPEEGKILNPDHPCFRPDSTKVESLVALLNNSSEMKLVQMKWHEACLSI
              550       560       570       580       590       600

             590       600       610       620       630       640 
pF1KA0 SAAILEILNAWENGVLAFESIQKITDNIKGKVCSLAVCAVAWLVAHVRMLGLDEREKSLQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SAAILEILNAWENGVLAFESIQKITDNIKGKVCSLAVCAVAWLVAHVRMLGLDEREKSLQ
              610       620       630       640       650       660

             650       660       670       680       690       700 
pF1KA0 MIRQLAGPLFSENTLQFYNERVVIMNSILERMCADVLQQTATQIKFPSTGVDTMPYWNLL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MIRQLAGPLFSENTLQFYNERVVIMNSILERMCADVLQQTATQIKFPSTGVDTMPYWNLL
              670       680       690       700       710       720

             710       720       730       740       750       760 
pF1KA0 PPKRPIKEVLTDIFAKVLEKGWVDSRSIHIFDTLLHMGGVYWFCNNLIKELLKETRKEHT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PPKRPIKEVLTDIFAKVLEKGWVDSRSIHIFDTLLHMGGVYWFCNNLIKELLKETRKEHT
              730       740       750       760       770       780

             770       780       790       800       810       820 
pF1KA0 LRAVELLYSIFCLDMQQVTLVLLGHILPGLLTDSSKWHSLMDPPGTALAKLAVWCALSSY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LRAVELLYSIFCLDMQQVTLVLLGHILPGLLTDSSKWHSLMDPPGTALAKLAVWCALSSY
              790       800       810       820       830       840

             830       840       850       860       870       880 
pF1KA0 SSHKGQASTRQKKRHREDIEDYISLFPLDDVQPSKLMRLLSSNEDDANILSSPTDRSMSS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SSHKGQASTRQKKRHREDIEDYISLFPLDDVQPSKLMRLLSSNEDDANILSSPTDRSMSS
              850       860       870       880       890       900

             890       900       910       920       930       940 
pF1KA0 SLSASQLHTVNMRDPLNRVLANLFLLISSILGSRTAGPHTQFVQWFMEECVDCLEQGGRG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SLSASQLHTVNMRDPLNRVLANLFLLISSILGSRTAGPHTQFVQWFMEECVDCLEQGGRG
              910       920       930       940       950       960

             950       960       970       980         
pF1KA0 SVLQFMPFTTVSELVKVSAMSSPKVVLAITDLSLPLGRQVAAKAIAAL
       ::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SVLQFMPFTTVSELVKVSAMSSPKVVLAITDLSLPLGRQVAAKAIAAL
              970       980       990      1000        




989 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Wed Nov  2 18:10:47 2016 done: Wed Nov  2 18:10:48 2016
 Total Scan time: 11.930 Total Display time:  0.360

Function used was FASTA [36.3.4 Apr, 2011]
Inquiries or Suggestions ?
Send a message to flexiclone AT kazusagt.com