Result of FASTA (omim) for
pFN21AB4546
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB4546, 3460 aa
1>>>pF1KB4546 3460 - 3460 aa - 3460 aa
Library: /omim/omim.rfq.tfa
61265892 residues in 86068 sequences
Statistics: Expectation_n fit: rho(ln(x))= 7.2231+/-0.000673; mu= 16.7871+/- 0.041
mean_var=114.6172+/-22.824, 0's: 0 Z-trim(106.8): 121 B-trim: 59 in 2/48
Lambda= 0.119798
statistics sampled from 14898 (14992) to 14898 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.486), E-opt: 0.2 (0.174), width: 16
Scan time: 19.150
The best scores are: opt bits E(86068)
NP_005036 (OMIM: 257320,600512,600514,616436) reel (3460) 24293 4212.4 0
NP_774959 (OMIM: 257320,600512,600514,616436) reel (3458) 24269 4208.2 0
NP_006099 (OMIM: 604989) spondin-1 precursor [Homo ( 807) 264 59.1 3.8e-07
>>NP_005036 (OMIM: 257320,600512,600514,616436) reelin i (3460 aa)
initn: 24293 init1: 24293 opt: 24293 Z-score: 22684.1 bits: 4212.4 E(86068): 0
Smith-Waterman score: 24293; 100.0% identity (100.0% similar) in 3460 aa overlap (1-3460:1-3460)
10 20 30 40 50 60
pF1KB4 MERSGWARQTFLLALLLGATLRARAAAGYYPRFSPFFFLCTHHGELEGDGEQGEVLISLH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 MERSGWARQTFLLALLLGATLRARAAAGYYPRFSPFFFLCTHHGELEGDGEQGEVLISLH
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB4 IAGNPTYYVPGQEYHVTISTSTFFDGLLVTGLYTSTSVQASQSIGGSSAFGFGIMSDHQF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 IAGNPTYYVPGQEYHVTISTSTFFDGLLVTGLYTSTSVQASQSIGGSSAFGFGIMSDHQF
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB4 GNQFMCSVVASHVSHLPTTNLSFIWIAPPAGTGCVNFMATATHRGQVIFKDALAQQLCEQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 GNQFMCSVVASHVSHLPTTNLSFIWIAPPAGTGCVNFMATATHRGQVIFKDALAQQLCEQ
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB4 GAPTDVTVHPHLAEIHSDSIILRDDFDSYHQLQLNPNIWVECNNCETGEQCGAIMHGNAV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 GAPTDVTVHPHLAEIHSDSIILRDDFDSYHQLQLNPNIWVECNNCETGEQCGAIMHGNAV
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB4 TFCEPYGPRELITTGLNTTTASVLQFSIGSGSCRFSYSDPSIIVLYAKNNSADWIQLEKI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 TFCEPYGPRELITTGLNTTTASVLQFSIGSGSCRFSYSDPSIIVLYAKNNSADWIQLEKI
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB4 RAPSNVSTIIHILYLPEDAKGENVQFQWKQENLRVGEVYEACWALDNILIINSAHRQVVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 RAPSNVSTIIHILYLPEDAKGENVQFQWKQENLRVGEVYEACWALDNILIINSAHRQVVL
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB4 EDSLDPVDTGNWLFFPGATVKHSCQSDGNSIYFHGNEGSEFNFATTRDVDLSTEDIQEQW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 EDSLDPVDTGNWLFFPGATVKHSCQSDGNSIYFHGNEGSEFNFATTRDVDLSTEDIQEQW
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB4 SEEFESQPTGWDVLGAVIGTECGTIESGLSMVFLKDGERKLCTPSMDTTGYGNLRFYFVM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 SEEFESQPTGWDVLGAVIGTECGTIESGLSMVFLKDGERKLCTPSMDTTGYGNLRFYFVM
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB4 GGICDPGNSHENDIILYAKIEGRKEHITLDTLSYSSYKVPSLVSVVINPELQTPATKFCL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 GGICDPGNSHENDIILYAKIEGRKEHITLDTLSYSSYKVPSLVSVVINPELQTPATKFCL
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB4 RQKNHQGHNRNVWAVDFFHVLPVLPSTMSHMIQFSINLGCGTHQPGNSVSLEFSTNHGRS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 RQKNHQGHNRNVWAVDFFHVLPVLPSTMSHMIQFSINLGCGTHQPGNSVSLEFSTNHGRS
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB4 WSLLHTECLPEICAGPHLPHSTVYSSENYSGWNRITIPLPNAALTRNTRIRWRQTGPILG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 WSLLHTECLPEICAGPHLPHSTVYSSENYSGWNRITIPLPNAALTRNTRIRWRQTGPILG
610 620 630 640 650 660
670 680 690 700 710 720
pF1KB4 NMWAIDNVYIGPSCLKFCSGRGQCTRHGCKCDPGFSGPACEMASQTFPMFISESFGSSRL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 NMWAIDNVYIGPSCLKFCSGRGQCTRHGCKCDPGFSGPACEMASQTFPMFISESFGSSRL
670 680 690 700 710 720
730 740 750 760 770 780
pF1KB4 SSYHNFYSIRGAEVSFGCGVLASGKALVFNKDGRRQLITSFLDSSQSRFLQFTLRLGSKS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 SSYHNFYSIRGAEVSFGCGVLASGKALVFNKDGRRQLITSFLDSSQSRFLQFTLRLGSKS
730 740 750 760 770 780
790 800 810 820 830 840
pF1KB4 VLSTCRAPDQPGEGVLLHYSYDNGITWKLLEHYSYLSYHEPRIISVELPGDAKQFGIQFR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 VLSTCRAPDQPGEGVLLHYSYDNGITWKLLEHYSYLSYHEPRIISVELPGDAKQFGIQFR
790 800 810 820 830 840
850 860 870 880 890 900
pF1KB4 WWQPYHSSQREDVWAIDEIIMTSVLFNSISLDFTNLVEVTQSLGFYLGNVQPYCGHDWTL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 WWQPYHSSQREDVWAIDEIIMTSVLFNSISLDFTNLVEVTQSLGFYLGNVQPYCGHDWTL
850 860 870 880 890 900
910 920 930 940 950 960
pF1KB4 CFTGDSKLASSMRYVETQSMQIGASYMIQFSLVMGCGQKYTPHMDNQVKLEYSTNHGLTW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 CFTGDSKLASSMRYVETQSMQIGASYMIQFSLVMGCGQKYTPHMDNQVKLEYSTNHGLTW
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KB4 HLVQEECLPSMPSCQEFTSASIYHASEFTQWRRVIVLLPQKTWSSATRFRWSQSYYTAQD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 HLVQEECLPSMPSCQEFTSASIYHASEFTQWRRVIVLLPQKTWSSATRFRWSQSYYTAQD
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KB4 EWALDSIYIGQQCPNMCSGHGSCDHGICRCDQGYQGTECHPEAALPSTIMSDFENQNGWE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 EWALDSIYIGQQCPNMCSGHGSCDHGICRCDQGYQGTECHPEAALPSTIMSDFENQNGWE
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KB4 SDWQEVIGGEIVKPEQGCGVISSGSSLYFSKAGKRQLVSWDLDTSWVDFVQFYIQIGGES
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 SDWQEVIGGEIVKPEQGCGVISSGSSLYFSKAGKRQLVSWDLDTSWVDFVQFYIQIGGES
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KB4 ASCNKPDSREEGVLLQYSNNGGIQWHLLAEMYFSDFSKPRFVYLELPAAAKTPCTRFRWW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 ASCNKPDSREEGVLLQYSNNGGIQWHLLAEMYFSDFSKPRFVYLELPAAAKTPCTRFRWW
1150 1160 1170 1180 1190 1200
1210 1220 1230 1240 1250 1260
pF1KB4 QPVFSGEDYDQWAVDDIIILSEKQKQIIPVINPTLPQNFYEKPAFDYPMNQMSVWLMLAN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 QPVFSGEDYDQWAVDDIIILSEKQKQIIPVINPTLPQNFYEKPAFDYPMNQMSVWLMLAN
1210 1220 1230 1240 1250 1260
1270 1280 1290 1300 1310 1320
pF1KB4 EGMVKNETFCAATPSAMIFGKSDGDRFAVTRDLTLKPGYVLQFKLNIGCANQFSSTAPVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 EGMVKNETFCAATPSAMIFGKSDGDRFAVTRDLTLKPGYVLQFKLNIGCANQFSSTAPVL
1270 1280 1290 1300 1310 1320
1330 1340 1350 1360 1370 1380
pF1KB4 LQYSHDAGMSWFLVKEGCYPASAGKGCEGNSRELSEPTMYHTGDFEEWTRITIVIPRSLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 LQYSHDAGMSWFLVKEGCYPASAGKGCEGNSRELSEPTMYHTGDFEEWTRITIVIPRSLA
1330 1340 1350 1360 1370 1380
1390 1400 1410 1420 1430 1440
pF1KB4 SSKTRFRWIQESSSQKNVPPFGLDGVYISEPCPSYCSGHGDCISGVCFCDLGYTAAQGTC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 SSKTRFRWIQESSSQKNVPPFGLDGVYISEPCPSYCSGHGDCISGVCFCDLGYTAAQGTC
1390 1400 1410 1420 1430 1440
1450 1460 1470 1480 1490 1500
pF1KB4 VSNVPNHNEMFDRFEGKLSPLWYKITGAQVGTGCGTLNDGKSLYFNGPGKREARTVPLDT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 VSNVPNHNEMFDRFEGKLSPLWYKITGAQVGTGCGTLNDGKSLYFNGPGKREARTVPLDT
1450 1460 1470 1480 1490 1500
1510 1520 1530 1540 1550 1560
pF1KB4 RNIRLVQFYIQIGSKTSGITCIKPRTRNEGLIVQYSNDNGILWHLLRELDFMSFLEPQII
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 RNIRLVQFYIQIGSKTSGITCIKPRTRNEGLIVQYSNDNGILWHLLRELDFMSFLEPQII
1510 1520 1530 1540 1550 1560
1570 1580 1590 1600 1610 1620
pF1KB4 SIDLPQDAKTPATAFRWWQPQHGKHSAQWALDDVLIGMNDSSQTGFQDKFDGSIDLQANW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 SIDLPQDAKTPATAFRWWQPQHGKHSAQWALDDVLIGMNDSSQTGFQDKFDGSIDLQANW
1570 1580 1590 1600 1610 1620
1630 1640 1650 1660 1670 1680
pF1KB4 YRIQGGQVDIDCLSMDTALIFTENIGKPRYAETWDFHVSASTFLQFEMSMGCSKPFSNSH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 YRIQGGQVDIDCLSMDTALIFTENIGKPRYAETWDFHVSASTFLQFEMSMGCSKPFSNSH
1630 1640 1650 1660 1670 1680
1690 1700 1710 1720 1730 1740
pF1KB4 SVQLQYSLNNGKDWHLVTEECVPPTIGCLHYTESSIYTSERFQNWKRITVYLPLSTISPR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 SVQLQYSLNNGKDWHLVTEECVPPTIGCLHYTESSIYTSERFQNWKRITVYLPLSTISPR
1690 1700 1710 1720 1730 1740
1750 1760 1770 1780 1790 1800
pF1KB4 TRFRWIQANYTVGADSWAIDNVVLASGCPWMCSGRGICDAGRCVCDRGFGGPYCVPVVPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 TRFRWIQANYTVGADSWAIDNVVLASGCPWMCSGRGICDAGRCVCDRGFGGPYCVPVVPL
1750 1760 1770 1780 1790 1800
1810 1820 1830 1840 1850 1860
pF1KB4 PSILKDDFNGNLHPDLWPEVYGAERGNLNGETIKSGTSLIFKGEGLRMLISRDLDCTNTM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 PSILKDDFNGNLHPDLWPEVYGAERGNLNGETIKSGTSLIFKGEGLRMLISRDLDCTNTM
1810 1820 1830 1840 1850 1860
1870 1880 1890 1900 1910 1920
pF1KB4 YVQFSLRFIAKSTPERSHSILLQFSISGGITWHLMDEFYFPQTTNILFINVPLPYTAQTN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 YVQFSLRFIAKSTPERSHSILLQFSISGGITWHLMDEFYFPQTTNILFINVPLPYTAQTN
1870 1880 1890 1900 1910 1920
1930 1940 1950 1960 1970 1980
pF1KB4 ATRFRLWQPYNNGKKEEIWIVDDFIIDGNNVNNPVMLLDTFDFGPREDNWFFYPGGNIGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 ATRFRLWQPYNNGKKEEIWIVDDFIIDGNNVNNPVMLLDTFDFGPREDNWFFYPGGNIGL
1930 1940 1950 1960 1970 1980
1990 2000 2010 2020 2030 2040
pF1KB4 YCPYSSKGAPEEDSAMVFVSNEVGEHSITTRDLNVNENTIIQFEINVGCSTDSSSADPVR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 YCPYSSKGAPEEDSAMVFVSNEVGEHSITTRDLNVNENTIIQFEINVGCSTDSSSADPVR
1990 2000 2010 2020 2030 2040
2050 2060 2070 2080 2090 2100
pF1KB4 LEFSRDFGATWHLLLPLCYHSSSHVSSLCSTEHHPSSTYYAGTMQGWRREVVHFGKLHLC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 LEFSRDFGATWHLLLPLCYHSSSHVSSLCSTEHHPSSTYYAGTMQGWRREVVHFGKLHLC
2050 2060 2070 2080 2090 2100
2110 2120 2130 2140 2150 2160
pF1KB4 GSVRFRWYQGFYPAGSQPVTWAIDNVYIGPQCEEMCNGQGSCINGTKCICDPGYSGPTCK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 GSVRFRWYQGFYPAGSQPVTWAIDNVYIGPQCEEMCNGQGSCINGTKCICDPGYSGPTCK
2110 2120 2130 2140 2150 2160
2170 2180 2190 2200 2210 2220
pF1KB4 ISTKNPDFLKDDFEGQLESDRFLLMSGGKPSRKCGILSSGNNLFFNEDGLRMLMTRDLDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 ISTKNPDFLKDDFEGQLESDRFLLMSGGKPSRKCGILSSGNNLFFNEDGLRMLMTRDLDL
2170 2180 2190 2200 2210 2220
2230 2240 2250 2260 2270 2280
pF1KB4 SHARFVQFFMRLGCGKGVPDPRSQPVLLQYSLNGGLSWSLLQEFLFSNSSNVGRYIALEI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 SHARFVQFFMRLGCGKGVPDPRSQPVLLQYSLNGGLSWSLLQEFLFSNSSNVGRYIALEI
2230 2240 2250 2260 2270 2280
2290 2300 2310 2320 2330 2340
pF1KB4 PLKARSGSTRLRWWQPSENGHFYSPWVIDQILIGGNISGNTVLEDDFTTLDSRKWLLHPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 PLKARSGSTRLRWWQPSENGHFYSPWVIDQILIGGNISGNTVLEDDFTTLDSRKWLLHPG
2290 2300 2310 2320 2330 2340
2350 2360 2370 2380 2390 2400
pF1KB4 GTKMPVCGSTGDALVFIEKASTRYVVSTDVAVNEDSFLQIDFAASCSVTDSCYAIELEYS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 GTKMPVCGSTGDALVFIEKASTRYVVSTDVAVNEDSFLQIDFAASCSVTDSCYAIELEYS
2350 2360 2370 2380 2390 2400
2410 2420 2430 2440 2450 2460
pF1KB4 VDLGLSWHPLVRDCLPTNVECSRYHLQRILVSDTFNKWTRITLPLPPYTRSQATRFRWHQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 VDLGLSWHPLVRDCLPTNVECSRYHLQRILVSDTFNKWTRITLPLPPYTRSQATRFRWHQ
2410 2420 2430 2440 2450 2460
2470 2480 2490 2500 2510 2520
pF1KB4 PAPFDKQQTWAIDNVYIGDGCIDMCSGHGRCIQGNCVCDEQWGGLYCDDPETSLPTQLKD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 PAPFDKQQTWAIDNVYIGDGCIDMCSGHGRCIQGNCVCDEQWGGLYCDDPETSLPTQLKD
2470 2480 2490 2500 2510 2520
2530 2540 2550 2560 2570 2580
pF1KB4 NFNRAPSSQNWLTVNGGKLSTVCGAVASGMALHFSGGCSRLLVTVDLNLTNAEFIQFYFM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 NFNRAPSSQNWLTVNGGKLSTVCGAVASGMALHFSGGCSRLLVTVDLNLTNAEFIQFYFM
2530 2540 2550 2560 2570 2580
2590 2600 2610 2620 2630 2640
pF1KB4 YGCLITPNNRNQGVLLEYSVNGGITWNLLMEIFYDQYSKPGFVNILLPPDAKEIATRFRW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 YGCLITPNNRNQGVLLEYSVNGGITWNLLMEIFYDQYSKPGFVNILLPPDAKEIATRFRW
2590 2600 2610 2620 2630 2640
2650 2660 2670 2680 2690 2700
pF1KB4 WQPRHDGLDQNDWAIDNVLISGSADQRTVMLDTFSSAPVPQHERSPADAGPVGRIAFDMF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 WQPRHDGLDQNDWAIDNVLISGSADQRTVMLDTFSSAPVPQHERSPADAGPVGRIAFDMF
2650 2660 2670 2680 2690 2700
2710 2720 2730 2740 2750 2760
pF1KB4 MEDKTSVNEHWLFHDDCTVERFCDSPDGVMLCGSHDGREVYAVTHDLTPTEGWIMQFKIS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 MEDKTSVNEHWLFHDDCTVERFCDSPDGVMLCGSHDGREVYAVTHDLTPTEGWIMQFKIS
2710 2720 2730 2740 2750 2760
2770 2780 2790 2800 2810 2820
pF1KB4 VGCKVSEKIAQNQIHVQYSTDFGVSWNYLVPQCLPADPKCSGSVSQPSVFFPTKGWKRIT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 VGCKVSEKIAQNQIHVQYSTDFGVSWNYLVPQCLPADPKCSGSVSQPSVFFPTKGWKRIT
2770 2780 2790 2800 2810 2820
2830 2840 2850 2860 2870 2880
pF1KB4 YPLPESLVGNPVRFRFYQKYSDMQWAIDNFYLGPGCLDNCRGHGDCLREQCICDPGYSGP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 YPLPESLVGNPVRFRFYQKYSDMQWAIDNFYLGPGCLDNCRGHGDCLREQCICDPGYSGP
2830 2840 2850 2860 2870 2880
2890 2900 2910 2920 2930 2940
pF1KB4 NCYLTHTLKTFLKERFDSEEIKPDLWMSLEGGSTCTECGILAEDTALYFGGSTVRQAVTQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 NCYLTHTLKTFLKERFDSEEIKPDLWMSLEGGSTCTECGILAEDTALYFGGSTVRQAVTQ
2890 2900 2910 2920 2930 2940
2950 2960 2970 2980 2990 3000
pF1KB4 DLDLRGAKFLQYWGRIGSENNMTSCHRPICRKEGVLLDYSTDGGITWTLLHEMDYQKYIS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 DLDLRGAKFLQYWGRIGSENNMTSCHRPICRKEGVLLDYSTDGGITWTLLHEMDYQKYIS
2950 2960 2970 2980 2990 3000
3010 3020 3030 3040 3050 3060
pF1KB4 VRHDYILLPEDALTNTTRLRWWQPFVISNGIVVSGVERAQWALDNILIGGAEINPSQLVD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 VRHDYILLPEDALTNTTRLRWWQPFVISNGIVVSGVERAQWALDNILIGGAEINPSQLVD
3010 3020 3030 3040 3050 3060
3070 3080 3090 3100 3110 3120
pF1KB4 TFDDEGTSHEENWSFYPNAVRTAGFCGNPSFHLYWPNKKKDKTHNALSSRELIIQPGYMM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 TFDDEGTSHEENWSFYPNAVRTAGFCGNPSFHLYWPNKKKDKTHNALSSRELIIQPGYMM
3070 3080 3090 3100 3110 3120
3130 3140 3150 3160 3170 3180
pF1KB4 QFKIVVGCEATSCGDLHSVMLEYTKDARSDSWQLVQTQCLPSSSNSIGCSPFQFHEATIY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 QFKIVVGCEATSCGDLHSVMLEYTKDARSDSWQLVQTQCLPSSSNSIGCSPFQFHEATIY
3130 3140 3150 3160 3170 3180
3190 3200 3210 3220 3230 3240
pF1KB4 NSVNSSSWKRITIQLPDHVSSSATQFRWIQKGEETEKQSWAIDHVYIGEACPKLCSGHGY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 NSVNSSSWKRITIQLPDHVSSSATQFRWIQKGEETEKQSWAIDHVYIGEACPKLCSGHGY
3190 3200 3210 3220 3230 3240
3250 3260 3270 3280 3290 3300
pF1KB4 CTTGAICICDESFQGDDCSVFSHDLPSYIKDNFESARVTEANWETIQGGVIGSGCGQLAP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 CTTGAICICDESFQGDDCSVFSHDLPSYIKDNFESARVTEANWETIQGGVIGSGCGQLAP
3250 3260 3270 3280 3290 3300
3310 3320 3330 3340 3350 3360
pF1KB4 YAHGDSLYFNGCQIRQAATKPLDLTRASKIMFVLQIGSMSQTDSCNSDLSGPHAVDKAVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 YAHGDSLYFNGCQIRQAATKPLDLTRASKIMFVLQIGSMSQTDSCNSDLSGPHAVDKAVL
3310 3320 3330 3340 3350 3360
3370 3380 3390 3400 3410 3420
pF1KB4 LQYSVNNGITWHVIAQHQPKDFTQAQRVSYNVPLEARMKGVLLRWWQPRHNGTGHDQWAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 LQYSVNNGITWHVIAQHQPKDFTQAQRVSYNVPLEARMKGVLLRWWQPRHNGTGHDQWAL
3370 3380 3390 3400 3410 3420
3430 3440 3450 3460
pF1KB4 DHVEVVLVSTRKQNYMMNFSRQHGLRHFYNRRRRSLRRYP
::::::::::::::::::::::::::::::::::::::::
NP_005 DHVEVVLVSTRKQNYMMNFSRQHGLRHFYNRRRRSLRRYP
3430 3440 3450 3460
>>NP_774959 (OMIM: 257320,600512,600514,616436) reelin i (3458 aa)
initn: 24062 init1: 24062 opt: 24269 Z-score: 22661.7 bits: 4208.2 E(86068): 0
Smith-Waterman score: 24269; 99.9% identity (99.9% similar) in 3460 aa overlap (1-3460:1-3458)
10 20 30 40 50 60
pF1KB4 MERSGWARQTFLLALLLGATLRARAAAGYYPRFSPFFFLCTHHGELEGDGEQGEVLISLH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_774 MERSGWARQTFLLALLLGATLRARAAAGYYPRFSPFFFLCTHHGELEGDGEQGEVLISLH
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB4 IAGNPTYYVPGQEYHVTISTSTFFDGLLVTGLYTSTSVQASQSIGGSSAFGFGIMSDHQF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_774 IAGNPTYYVPGQEYHVTISTSTFFDGLLVTGLYTSTSVQASQSIGGSSAFGFGIMSDHQF
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB4 GNQFMCSVVASHVSHLPTTNLSFIWIAPPAGTGCVNFMATATHRGQVIFKDALAQQLCEQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_774 GNQFMCSVVASHVSHLPTTNLSFIWIAPPAGTGCVNFMATATHRGQVIFKDALAQQLCEQ
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB4 GAPTDVTVHPHLAEIHSDSIILRDDFDSYHQLQLNPNIWVECNNCETGEQCGAIMHGNAV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_774 GAPTDVTVHPHLAEIHSDSIILRDDFDSYHQLQLNPNIWVECNNCETGEQCGAIMHGNAV
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB4 TFCEPYGPRELITTGLNTTTASVLQFSIGSGSCRFSYSDPSIIVLYAKNNSADWIQLEKI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_774 TFCEPYGPRELITTGLNTTTASVLQFSIGSGSCRFSYSDPSIIVLYAKNNSADWIQLEKI
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB4 RAPSNVSTIIHILYLPEDAKGENVQFQWKQENLRVGEVYEACWALDNILIINSAHRQVVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_774 RAPSNVSTIIHILYLPEDAKGENVQFQWKQENLRVGEVYEACWALDNILIINSAHRQVVL
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB4 EDSLDPVDTGNWLFFPGATVKHSCQSDGNSIYFHGNEGSEFNFATTRDVDLSTEDIQEQW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_774 EDSLDPVDTGNWLFFPGATVKHSCQSDGNSIYFHGNEGSEFNFATTRDVDLSTEDIQEQW
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB4 SEEFESQPTGWDVLGAVIGTECGTIESGLSMVFLKDGERKLCTPSMDTTGYGNLRFYFVM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_774 SEEFESQPTGWDVLGAVIGTECGTIESGLSMVFLKDGERKLCTPSMDTTGYGNLRFYFVM
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB4 GGICDPGNSHENDIILYAKIEGRKEHITLDTLSYSSYKVPSLVSVVINPELQTPATKFCL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_774 GGICDPGNSHENDIILYAKIEGRKEHITLDTLSYSSYKVPSLVSVVINPELQTPATKFCL
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB4 RQKNHQGHNRNVWAVDFFHVLPVLPSTMSHMIQFSINLGCGTHQPGNSVSLEFSTNHGRS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_774 RQKNHQGHNRNVWAVDFFHVLPVLPSTMSHMIQFSINLGCGTHQPGNSVSLEFSTNHGRS
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB4 WSLLHTECLPEICAGPHLPHSTVYSSENYSGWNRITIPLPNAALTRNTRIRWRQTGPILG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_774 WSLLHTECLPEICAGPHLPHSTVYSSENYSGWNRITIPLPNAALTRNTRIRWRQTGPILG
610 620 630 640 650 660
670 680 690 700 710 720
pF1KB4 NMWAIDNVYIGPSCLKFCSGRGQCTRHGCKCDPGFSGPACEMASQTFPMFISESFGSSRL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_774 NMWAIDNVYIGPSCLKFCSGRGQCTRHGCKCDPGFSGPACEMASQTFPMFISESFGSSRL
670 680 690 700 710 720
730 740 750 760 770 780
pF1KB4 SSYHNFYSIRGAEVSFGCGVLASGKALVFNKDGRRQLITSFLDSSQSRFLQFTLRLGSKS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_774 SSYHNFYSIRGAEVSFGCGVLASGKALVFNKDGRRQLITSFLDSSQSRFLQFTLRLGSKS
730 740 750 760 770 780
790 800 810 820 830 840
pF1KB4 VLSTCRAPDQPGEGVLLHYSYDNGITWKLLEHYSYLSYHEPRIISVELPGDAKQFGIQFR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_774 VLSTCRAPDQPGEGVLLHYSYDNGITWKLLEHYSYLSYHEPRIISVELPGDAKQFGIQFR
790 800 810 820 830 840
850 860 870 880 890 900
pF1KB4 WWQPYHSSQREDVWAIDEIIMTSVLFNSISLDFTNLVEVTQSLGFYLGNVQPYCGHDWTL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_774 WWQPYHSSQREDVWAIDEIIMTSVLFNSISLDFTNLVEVTQSLGFYLGNVQPYCGHDWTL
850 860 870 880 890 900
910 920 930 940 950 960
pF1KB4 CFTGDSKLASSMRYVETQSMQIGASYMIQFSLVMGCGQKYTPHMDNQVKLEYSTNHGLTW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_774 CFTGDSKLASSMRYVETQSMQIGASYMIQFSLVMGCGQKYTPHMDNQVKLEYSTNHGLTW
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KB4 HLVQEECLPSMPSCQEFTSASIYHASEFTQWRRVIVLLPQKTWSSATRFRWSQSYYTAQD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_774 HLVQEECLPSMPSCQEFTSASIYHASEFTQWRRVIVLLPQKTWSSATRFRWSQSYYTAQD
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KB4 EWALDSIYIGQQCPNMCSGHGSCDHGICRCDQGYQGTECHPEAALPSTIMSDFENQNGWE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_774 EWALDSIYIGQQCPNMCSGHGSCDHGICRCDQGYQGTECHPEAALPSTIMSDFENQNGWE
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KB4 SDWQEVIGGEIVKPEQGCGVISSGSSLYFSKAGKRQLVSWDLDTSWVDFVQFYIQIGGES
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_774 SDWQEVIGGEIVKPEQGCGVISSGSSLYFSKAGKRQLVSWDLDTSWVDFVQFYIQIGGES
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KB4 ASCNKPDSREEGVLLQYSNNGGIQWHLLAEMYFSDFSKPRFVYLELPAAAKTPCTRFRWW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_774 ASCNKPDSREEGVLLQYSNNGGIQWHLLAEMYFSDFSKPRFVYLELPAAAKTPCTRFRWW
1150 1160 1170 1180 1190 1200
1210 1220 1230 1240 1250 1260
pF1KB4 QPVFSGEDYDQWAVDDIIILSEKQKQIIPVINPTLPQNFYEKPAFDYPMNQMSVWLMLAN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_774 QPVFSGEDYDQWAVDDIIILSEKQKQIIPVINPTLPQNFYEKPAFDYPMNQMSVWLMLAN
1210 1220 1230 1240 1250 1260
1270 1280 1290 1300 1310 1320
pF1KB4 EGMVKNETFCAATPSAMIFGKSDGDRFAVTRDLTLKPGYVLQFKLNIGCANQFSSTAPVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_774 EGMVKNETFCAATPSAMIFGKSDGDRFAVTRDLTLKPGYVLQFKLNIGCANQFSSTAPVL
1270 1280 1290 1300 1310 1320
1330 1340 1350 1360 1370 1380
pF1KB4 LQYSHDAGMSWFLVKEGCYPASAGKGCEGNSRELSEPTMYHTGDFEEWTRITIVIPRSLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_774 LQYSHDAGMSWFLVKEGCYPASAGKGCEGNSRELSEPTMYHTGDFEEWTRITIVIPRSLA
1330 1340 1350 1360 1370 1380
1390 1400 1410 1420 1430 1440
pF1KB4 SSKTRFRWIQESSSQKNVPPFGLDGVYISEPCPSYCSGHGDCISGVCFCDLGYTAAQGTC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_774 SSKTRFRWIQESSSQKNVPPFGLDGVYISEPCPSYCSGHGDCISGVCFCDLGYTAAQGTC
1390 1400 1410 1420 1430 1440
1450 1460 1470 1480 1490 1500
pF1KB4 VSNVPNHNEMFDRFEGKLSPLWYKITGAQVGTGCGTLNDGKSLYFNGPGKREARTVPLDT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_774 VSNVPNHNEMFDRFEGKLSPLWYKITGAQVGTGCGTLNDGKSLYFNGPGKREARTVPLDT
1450 1460 1470 1480 1490 1500
1510 1520 1530 1540 1550 1560
pF1KB4 RNIRLVQFYIQIGSKTSGITCIKPRTRNEGLIVQYSNDNGILWHLLRELDFMSFLEPQII
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_774 RNIRLVQFYIQIGSKTSGITCIKPRTRNEGLIVQYSNDNGILWHLLRELDFMSFLEPQII
1510 1520 1530 1540 1550 1560
1570 1580 1590 1600 1610 1620
pF1KB4 SIDLPQDAKTPATAFRWWQPQHGKHSAQWALDDVLIGMNDSSQTGFQDKFDGSIDLQANW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_774 SIDLPQDAKTPATAFRWWQPQHGKHSAQWALDDVLIGMNDSSQTGFQDKFDGSIDLQANW
1570 1580 1590 1600 1610 1620
1630 1640 1650 1660 1670 1680
pF1KB4 YRIQGGQVDIDCLSMDTALIFTENIGKPRYAETWDFHVSASTFLQFEMSMGCSKPFSNSH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_774 YRIQGGQVDIDCLSMDTALIFTENIGKPRYAETWDFHVSASTFLQFEMSMGCSKPFSNSH
1630 1640 1650 1660 1670 1680
1690 1700 1710 1720 1730 1740
pF1KB4 SVQLQYSLNNGKDWHLVTEECVPPTIGCLHYTESSIYTSERFQNWKRITVYLPLSTISPR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_774 SVQLQYSLNNGKDWHLVTEECVPPTIGCLHYTESSIYTSERFQNWKRITVYLPLSTISPR
1690 1700 1710 1720 1730 1740
1750 1760 1770 1780 1790 1800
pF1KB4 TRFRWIQANYTVGADSWAIDNVVLASGCPWMCSGRGICDAGRCVCDRGFGGPYCVPVVPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_774 TRFRWIQANYTVGADSWAIDNVVLASGCPWMCSGRGICDAGRCVCDRGFGGPYCVPVVPL
1750 1760 1770 1780 1790 1800
1810 1820 1830 1840 1850 1860
pF1KB4 PSILKDDFNGNLHPDLWPEVYGAERGNLNGETIKSGTSLIFKGEGLRMLISRDLDCTNTM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_774 PSILKDDFNGNLHPDLWPEVYGAERGNLNGETIKSGTSLIFKGEGLRMLISRDLDCTNTM
1810 1820 1830 1840 1850 1860
1870 1880 1890 1900 1910 1920
pF1KB4 YVQFSLRFIAKSTPERSHSILLQFSISGGITWHLMDEFYFPQTTNILFINVPLPYTAQTN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_774 YVQFSLRFIAKSTPERSHSILLQFSISGGITWHLMDEFYFPQTTNILFINVPLPYTAQTN
1870 1880 1890 1900 1910 1920
1930 1940 1950 1960 1970 1980
pF1KB4 ATRFRLWQPYNNGKKEEIWIVDDFIIDGNNVNNPVMLLDTFDFGPREDNWFFYPGGNIGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_774 ATRFRLWQPYNNGKKEEIWIVDDFIIDGNNVNNPVMLLDTFDFGPREDNWFFYPGGNIGL
1930 1940 1950 1960 1970 1980
1990 2000 2010 2020 2030 2040
pF1KB4 YCPYSSKGAPEEDSAMVFVSNEVGEHSITTRDLNVNENTIIQFEINVGCSTDSSSADPVR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_774 YCPYSSKGAPEEDSAMVFVSNEVGEHSITTRDLNVNENTIIQFEINVGCSTDSSSADPVR
1990 2000 2010 2020 2030 2040
2050 2060 2070 2080 2090 2100
pF1KB4 LEFSRDFGATWHLLLPLCYHSSSHVSSLCSTEHHPSSTYYAGTMQGWRREVVHFGKLHLC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_774 LEFSRDFGATWHLLLPLCYHSSSHVSSLCSTEHHPSSTYYAGTMQGWRREVVHFGKLHLC
2050 2060 2070 2080 2090 2100
2110 2120 2130 2140 2150 2160
pF1KB4 GSVRFRWYQGFYPAGSQPVTWAIDNVYIGPQCEEMCNGQGSCINGTKCICDPGYSGPTCK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_774 GSVRFRWYQGFYPAGSQPVTWAIDNVYIGPQCEEMCNGQGSCINGTKCICDPGYSGPTCK
2110 2120 2130 2140 2150 2160
2170 2180 2190 2200 2210 2220
pF1KB4 ISTKNPDFLKDDFEGQLESDRFLLMSGGKPSRKCGILSSGNNLFFNEDGLRMLMTRDLDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_774 ISTKNPDFLKDDFEGQLESDRFLLMSGGKPSRKCGILSSGNNLFFNEDGLRMLMTRDLDL
2170 2180 2190 2200 2210 2220
2230 2240 2250 2260 2270 2280
pF1KB4 SHARFVQFFMRLGCGKGVPDPRSQPVLLQYSLNGGLSWSLLQEFLFSNSSNVGRYIALEI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_774 SHARFVQFFMRLGCGKGVPDPRSQPVLLQYSLNGGLSWSLLQEFLFSNSSNVGRYIALEI
2230 2240 2250 2260 2270 2280
2290 2300 2310 2320 2330 2340
pF1KB4 PLKARSGSTRLRWWQPSENGHFYSPWVIDQILIGGNISGNTVLEDDFTTLDSRKWLLHPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_774 PLKARSGSTRLRWWQPSENGHFYSPWVIDQILIGGNISGNTVLEDDFTTLDSRKWLLHPG
2290 2300 2310 2320 2330 2340
2350 2360 2370 2380 2390 2400
pF1KB4 GTKMPVCGSTGDALVFIEKASTRYVVSTDVAVNEDSFLQIDFAASCSVTDSCYAIELEYS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_774 GTKMPVCGSTGDALVFIEKASTRYVVSTDVAVNEDSFLQIDFAASCSVTDSCYAIELEYS
2350 2360 2370 2380 2390 2400
2410 2420 2430 2440 2450 2460
pF1KB4 VDLGLSWHPLVRDCLPTNVECSRYHLQRILVSDTFNKWTRITLPLPPYTRSQATRFRWHQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_774 VDLGLSWHPLVRDCLPTNVECSRYHLQRILVSDTFNKWTRITLPLPPYTRSQATRFRWHQ
2410 2420 2430 2440 2450 2460
2470 2480 2490 2500 2510 2520
pF1KB4 PAPFDKQQTWAIDNVYIGDGCIDMCSGHGRCIQGNCVCDEQWGGLYCDDPETSLPTQLKD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_774 PAPFDKQQTWAIDNVYIGDGCIDMCSGHGRCIQGNCVCDEQWGGLYCDDPETSLPTQLKD
2470 2480 2490 2500 2510 2520
2530 2540 2550 2560 2570 2580
pF1KB4 NFNRAPSSQNWLTVNGGKLSTVCGAVASGMALHFSGGCSRLLVTVDLNLTNAEFIQFYFM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_774 NFNRAPSSQNWLTVNGGKLSTVCGAVASGMALHFSGGCSRLLVTVDLNLTNAEFIQFYFM
2530 2540 2550 2560 2570 2580
2590 2600 2610 2620 2630 2640
pF1KB4 YGCLITPNNRNQGVLLEYSVNGGITWNLLMEIFYDQYSKPGFVNILLPPDAKEIATRFRW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_774 YGCLITPNNRNQGVLLEYSVNGGITWNLLMEIFYDQYSKPGFVNILLPPDAKEIATRFRW
2590 2600 2610 2620 2630 2640
2650 2660 2670 2680 2690 2700
pF1KB4 WQPRHDGLDQNDWAIDNVLISGSADQRTVMLDTFSSAPVPQHERSPADAGPVGRIAFDMF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_774 WQPRHDGLDQNDWAIDNVLISGSADQRTVMLDTFSSAPVPQHERSPADAGPVGRIAFDMF
2650 2660 2670 2680 2690 2700
2710 2720 2730 2740 2750 2760
pF1KB4 MEDKTSVNEHWLFHDDCTVERFCDSPDGVMLCGSHDGREVYAVTHDLTPTEGWIMQFKIS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_774 MEDKTSVNEHWLFHDDCTVERFCDSPDGVMLCGSHDGREVYAVTHDLTPTEGWIMQFKIS
2710 2720 2730 2740 2750 2760
2770 2780 2790 2800 2810 2820
pF1KB4 VGCKVSEKIAQNQIHVQYSTDFGVSWNYLVPQCLPADPKCSGSVSQPSVFFPTKGWKRIT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_774 VGCKVSEKIAQNQIHVQYSTDFGVSWNYLVPQCLPADPKCSGSVSQPSVFFPTKGWKRIT
2770 2780 2790 2800 2810 2820
2830 2840 2850 2860 2870 2880
pF1KB4 YPLPESLVGNPVRFRFYQKYSDMQWAIDNFYLGPGCLDNCRGHGDCLREQCICDPGYSGP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_774 YPLPESLVGNPVRFRFYQKYSDMQWAIDNFYLGPGCLDNCRGHGDCLREQCICDPGYSGP
2830 2840 2850 2860 2870 2880
2890 2900 2910 2920 2930 2940
pF1KB4 NCYLTHTLKTFLKERFDSEEIKPDLWMSLEGGSTCTECGILAEDTALYFGGSTVRQAVTQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_774 NCYLTHTLKTFLKERFDSEEIKPDLWMSLEGGSTCTECGILAEDTALYFGGSTVRQAVTQ
2890 2900 2910 2920 2930 2940
2950 2960 2970 2980 2990 3000
pF1KB4 DLDLRGAKFLQYWGRIGSENNMTSCHRPICRKEGVLLDYSTDGGITWTLLHEMDYQKYIS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_774 DLDLRGAKFLQYWGRIGSENNMTSCHRPICRKEGVLLDYSTDGGITWTLLHEMDYQKYIS
2950 2960 2970 2980 2990 3000
3010 3020 3030 3040 3050 3060
pF1KB4 VRHDYILLPEDALTNTTRLRWWQPFVISNGIVVSGVERAQWALDNILIGGAEINPSQLVD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_774 VRHDYILLPEDALTNTTRLRWWQPFVISNGIVVSGVERAQWALDNILIGGAEINPSQLVD
3010 3020 3030 3040 3050 3060
3070 3080 3090 3100 3110 3120
pF1KB4 TFDDEGTSHEENWSFYPNAVRTAGFCGNPSFHLYWPNKKKDKTHNALSSRELIIQPGYMM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_774 TFDDEGTSHEENWSFYPNAVRTAGFCGNPSFHLYWPNKKKDKTHNALSSRELIIQPGYMM
3070 3080 3090 3100 3110 3120
3130 3140 3150 3160 3170 3180
pF1KB4 QFKIVVGCEATSCGDLHSVMLEYTKDARSDSWQLVQTQCLPSSSNSIGCSPFQFHEATIY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_774 QFKIVVGCEATSCGDLHSVMLEYTKDARSDSWQLVQTQCLPSSSNSIGCSPFQFHEATIY
3130 3140 3150 3160 3170 3180
3190 3200 3210 3220 3230 3240
pF1KB4 NSVNSSSWKRITIQLPDHVSSSATQFRWIQKGEETEKQSWAIDHVYIGEACPKLCSGHGY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_774 NSVNSSSWKRITIQLPDHVSSSATQFRWIQKGEETEKQSWAIDHVYIGEACPKLCSGHGY
3190 3200 3210 3220 3230 3240
3250 3260 3270 3280 3290 3300
pF1KB4 CTTGAICICDESFQGDDCSVFSHDLPSYIKDNFESARVTEANWETIQGGVIGSGCGQLAP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_774 CTTGAICICDESFQGDDCSVFSHDLPSYIKDNFESARVTEANWETIQGGVIGSGCGQLAP
3250 3260 3270 3280 3290 3300
3310 3320 3330 3340 3350 3360
pF1KB4 YAHGDSLYFNGCQIRQAATKPLDLTRASKIMFVLQIGSMSQTDSCNSDLSGPHAVDKAVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_774 YAHGDSLYFNGCQIRQAATKPLDLTRASKIMFVLQIGSMSQTDSCNSDLSGPHAVDKAVL
3310 3320 3330 3340 3350 3360
3370 3380 3390 3400 3410 3420
pF1KB4 LQYSVNNGITWHVIAQHQPKDFTQAQRVSYNVPLEARMKGVLLRWWQPRHNGTGHDQWAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_774 LQYSVNNGITWHVIAQHQPKDFTQAQRVSYNVPLEARMKGVLLRWWQPRHNGTGHDQWAL
3370 3380 3390 3400 3410 3420
3430 3440 3450 3460
pF1KB4 DHVEVVLVSTRKQNYMMNFSRQHGLRHFYNRRRRSLRRYP
::::::: :::::::::::::::::::::::::::::::
NP_774 DHVEVVL--TRKQNYMMNFSRQHGLRHFYNRRRRSLRRYP
3430 3440 3450
>>NP_006099 (OMIM: 604989) spondin-1 precursor [Homo sap (807 aa)
initn: 151 init1: 115 opt: 264 Z-score: 249.4 bits: 59.1 E(86068): 3.8e-07
Smith-Waterman score: 264; 31.2% identity (65.0% similar) in 160 aa overlap (40-192:44-197)
10 20 30 40 50 60
pF1KB4 TFLLALLLGATLRARAAAGYYPRFSPFFFLCTHHGELEGDGEQGEVLISLHIAGNPTYYV
:.. . .: ..: . .::.. :.: .:
NP_006 PALLALALPLAAALAFSDETLDKVPKSEGYCSRILRAQGTRREGYTEFSLRVEGDPDFYK
20 30 40 50 60 70
70 80 90 100 110 120
pF1KB4 PGQEYHVTISTS--TFFDGLLVTGLYTSTSVQASQSIGGSSAFGFGIMSDHQFGNQFM--
:: :.::.:.. ..: :. . .: . . .. .:. : :..... .:::
NP_006 PGTSYRVTLSAAPPSYFRGFTLIALRENREGDKEEDHAGT----FQIIDEEE--TQFMSN
80 90 100 110 120
130 140 150 160 170 180
pF1KB4 CSVVASHVSHLPTTNLSFIWIAPPAGTGCVNFMATATHRGQVIFKD--ALAQQLCEQGAP
: :.... . : .. .::::::::::: . :. ... . :.: .:...:::: .
NP_006 CPVAVTESTPRRRTRIQVFWIAPPAGTGCVILKASIVQKRIIYFQDEGSLTKKLCEQDST
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB4 TD-VTVHPHLAEIHSDSIILRDDFDSYHQLQLNPNIWVECNNCETGEQCGAIMHGNAVTF
: :: .: :
NP_006 FDGVTDKPILDCCACGTAKYRLTFYGNWSEKTHPKDYPRRANHWSAIIGGSHSKNYVLWE
190 200 210 220 230 240
3460 residues in 1 query sequences
61265892 residues in 86068 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Thu Feb 2 14:38:50 2017 done: Thu Feb 2 14:38:53 2017
Total Scan time: 19.150 Total Display time: 0.620
Function used was FASTA [36.3.4 Apr, 2011]