Result of FASTA (omim) for
pFN21AE2450
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE2450, 321 aa
1>>>pF1KE2450 321 - 321 aa - 321 aa
Library: /omim/omim.rfq.tfa
64092750 residues in 91774 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.0177+/-0.000296; mu= 17.6614+/- 0.018
mean_var=72.7082+/-14.764, 0's: 0 Z-trim(117.2): 114 B-trim: 1799 in 1/52
Lambda= 0.150412
statistics sampled from 29942 (30063) to 29942 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.697), E-opt: 0.2 (0.328), width: 16
Scan time: 3.710
The best scores are: opt bits E(91774)
XP_016877373 (OMIM: 118511,612001) neuronal acetyl ( 321) 2206 487.7 1.5e-137
XP_005254807 (OMIM: 609756) CHRNA7-FAM7A fusion pr ( 321) 2206 487.7 1.5e-137
NP_683709 (OMIM: 609756) CHRNA7-FAM7A fusion prote ( 321) 2206 487.7 1.5e-137
XP_011519479 (OMIM: 118511,612001) neuronal acetyl ( 401) 2206 487.8 1.7e-137
NP_647536 (OMIM: 609756) CHRNA7-FAM7A fusion prote ( 412) 2206 487.8 1.8e-137
XP_011520455 (OMIM: 609756) CHRNA7-FAM7A fusion pr ( 412) 2206 487.8 1.8e-137
XP_016877372 (OMIM: 118511,612001) neuronal acetyl ( 440) 2206 487.8 1.9e-137
XP_016877371 (OMIM: 118511,612001) neuronal acetyl ( 441) 2206 487.8 1.9e-137
XP_011519478 (OMIM: 118511,612001) neuronal acetyl ( 486) 2206 487.8 2e-137
NP_000737 (OMIM: 118511,612001) neuronal acetylcho ( 502) 2206 487.8 2.1e-137
NP_001177384 (OMIM: 118511,612001) neuronal acetyl ( 531) 2206 487.9 2.2e-137
XP_011520457 (OMIM: 609756) CHRNA7-FAM7A fusion pr ( 290) 744 170.4 4.4e-42
XP_011519480 (OMIM: 118511,612001) neuronal acetyl ( 380) 744 170.5 5.3e-42
NP_001334636 (OMIM: 118502,610353) neuronal acetyl ( 331) 682 157.0 5.4e-38
NP_001334637 (OMIM: 118502,610353) neuronal acetyl ( 331) 682 157.0 5.4e-38
XP_011542691 (OMIM: 118502,610353) neuronal acetyl ( 331) 682 157.0 5.4e-38
NP_001334635 (OMIM: 118502,610353) neuronal acetyl ( 370) 682 157.0 5.9e-38
NP_001334634 (OMIM: 118502,610353) neuronal acetyl ( 370) 682 157.0 5.9e-38
NP_001269384 (OMIM: 118502,610353) neuronal acetyl ( 514) 682 157.1 7.5e-38
NP_000733 (OMIM: 118502,610353) neuronal acetylcho ( 529) 682 157.1 7.7e-38
XP_006720445 (OMIM: 118503,612052) neuronal acetyl ( 438) 656 151.4 3.3e-36
NP_000734 (OMIM: 118503,612052) neuronal acetylcho ( 505) 656 151.5 3.7e-36
NP_001243502 (OMIM: 118504,188890,600513) neuronal ( 451) 577 134.3 4.9e-31
XP_024307590 (OMIM: 118504,188890,600513) neuronal ( 451) 577 134.3 4.9e-31
XP_016883114 (OMIM: 118504,188890,600513) neuronal ( 451) 577 134.3 4.9e-31
XP_011526826 (OMIM: 118504,188890,600513) neuronal ( 556) 577 134.4 5.8e-31
NP_000735 (OMIM: 118504,188890,600513) neuronal ac ( 627) 577 134.4 6.3e-31
NP_001160166 (OMIM: 118503,612052) neuronal acetyl ( 489) 567 132.2 2.4e-30
NP_060051 (OMIM: 605116) neuronal acetylcholine re ( 479) 563 131.3 4.2e-30
NP_065135 (OMIM: 606372) neuronal acetylcholine re ( 450) 557 130.0 1e-29
XP_011519494 (OMIM: 118509) neuronal acetylcholine ( 316) 538 125.7 1.3e-28
XP_011519492 (OMIM: 118509) neuronal acetylcholine ( 424) 538 125.8 1.7e-28
XP_011519493 (OMIM: 118509) neuronal acetylcholine ( 424) 538 125.8 1.7e-28
XP_016877378 (OMIM: 118509) neuronal acetylcholine ( 449) 538 125.8 1.7e-28
XP_016877377 (OMIM: 118509) neuronal acetylcholine ( 462) 538 125.9 1.8e-28
XP_016877376 (OMIM: 118509) neuronal acetylcholine ( 463) 538 125.9 1.8e-28
XP_016877375 (OMIM: 118509) neuronal acetylcholine ( 468) 538 125.9 1.8e-28
XP_016877374 (OMIM: 118509) neuronal acetylcholine ( 468) 538 125.9 1.8e-28
XP_011519489 (OMIM: 118509) neuronal acetylcholine ( 495) 538 125.9 1.9e-28
XP_011519488 (OMIM: 118509) neuronal acetylcholine ( 495) 538 125.9 1.9e-28
NP_000741 (OMIM: 118509) neuronal acetylcholine re ( 498) 538 125.9 1.9e-28
XP_016855669 (OMIM: 118507,605375) neuronal acetyl ( 332) 525 122.9 9.8e-28
NP_000739 (OMIM: 118507,605375) neuronal acetylcho ( 502) 525 123.1 1.3e-27
NP_001186208 (OMIM: 606888) neuronal acetylcholine ( 479) 522 122.4 2e-27
NP_004189 (OMIM: 606888) neuronal acetylcholine re ( 494) 522 122.4 2.1e-27
NP_001289964 (OMIM: 606372) neuronal acetylcholine ( 244) 511 119.8 6.3e-27
NP_001289963 (OMIM: 606372) neuronal acetylcholine ( 244) 511 119.8 6.3e-27
XP_011518536 (OMIM: 606372) neuronal acetylcholine ( 244) 511 119.8 6.3e-27
NP_000070 (OMIM: 100690,253290,601462,608930) acet ( 457) 509 119.6 1.4e-26
XP_016858746 (OMIM: 100690,253290,601462,608930) a ( 464) 509 119.6 1.4e-26
>>XP_016877373 (OMIM: 118511,612001) neuronal acetylchol (321 aa)
initn: 2206 init1: 2206 opt: 2206 Z-score: 2591.1 bits: 487.7 E(91774): 1.5e-137
Smith-Waterman score: 2206; 100.0% identity (100.0% similar) in 321 aa overlap (1-321:1-321)
10 20 30 40 50 60
pF1KE2 MQEADISGYIPNGEWDLVGIPGKRSERFYECCKEPYPDVTFTVTMRRRTLYYGLNLLIPC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MQEADISGYIPNGEWDLVGIPGKRSERFYECCKEPYPDVTFTVTMRRRTLYYGLNLLIPC
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 VLISALALLVFLLPADSGEKISLGITVLLSLTVFMLLVAEIMPATSDSVPLIAQYFASTM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VLISALALLVFLLPADSGEKISLGITVLLSLTVFMLLVAEIMPATSDSVPLIAQYFASTM
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 IIVGLSVVVTVIVLQYHHHDPDGGKMPKWTRVILLNWCAWFLRMKRPGEDKVRPACQHKQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IIVGLSVVVTVIVLQYHHHDPDGGKMPKWTRVILLNWCAWFLRMKRPGEDKVRPACQHKQ
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE2 RRCSLASVEMSAVAPPPASNGNLLYIGFRGLDGVHCVPTPDSGVVCGRMACSPTHDEHLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RRCSLASVEMSAVAPPPASNGNLLYIGFRGLDGVHCVPTPDSGVVCGRMACSPTHDEHLL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE2 HGGQPPEGDPDLAKILEEVRYIANRFRCQDESEAVCSEWKFAACVVDRLCLMAFSVFTII
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HGGQPPEGDPDLAKILEEVRYIANRFRCQDESEAVCSEWKFAACVVDRLCLMAFSVFTII
250 260 270 280 290 300
310 320
pF1KE2 CTIGILMSAPNFVEAVSKDFA
:::::::::::::::::::::
XP_016 CTIGILMSAPNFVEAVSKDFA
310 320
>>XP_005254807 (OMIM: 609756) CHRNA7-FAM7A fusion protei (321 aa)
initn: 2206 init1: 2206 opt: 2206 Z-score: 2591.1 bits: 487.7 E(91774): 1.5e-137
Smith-Waterman score: 2206; 100.0% identity (100.0% similar) in 321 aa overlap (1-321:1-321)
10 20 30 40 50 60
pF1KE2 MQEADISGYIPNGEWDLVGIPGKRSERFYECCKEPYPDVTFTVTMRRRTLYYGLNLLIPC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MQEADISGYIPNGEWDLVGIPGKRSERFYECCKEPYPDVTFTVTMRRRTLYYGLNLLIPC
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 VLISALALLVFLLPADSGEKISLGITVLLSLTVFMLLVAEIMPATSDSVPLIAQYFASTM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VLISALALLVFLLPADSGEKISLGITVLLSLTVFMLLVAEIMPATSDSVPLIAQYFASTM
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 IIVGLSVVVTVIVLQYHHHDPDGGKMPKWTRVILLNWCAWFLRMKRPGEDKVRPACQHKQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 IIVGLSVVVTVIVLQYHHHDPDGGKMPKWTRVILLNWCAWFLRMKRPGEDKVRPACQHKQ
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE2 RRCSLASVEMSAVAPPPASNGNLLYIGFRGLDGVHCVPTPDSGVVCGRMACSPTHDEHLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RRCSLASVEMSAVAPPPASNGNLLYIGFRGLDGVHCVPTPDSGVVCGRMACSPTHDEHLL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE2 HGGQPPEGDPDLAKILEEVRYIANRFRCQDESEAVCSEWKFAACVVDRLCLMAFSVFTII
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 HGGQPPEGDPDLAKILEEVRYIANRFRCQDESEAVCSEWKFAACVVDRLCLMAFSVFTII
250 260 270 280 290 300
310 320
pF1KE2 CTIGILMSAPNFVEAVSKDFA
:::::::::::::::::::::
XP_005 CTIGILMSAPNFVEAVSKDFA
310 320
>>NP_683709 (OMIM: 609756) CHRNA7-FAM7A fusion protein i (321 aa)
initn: 2206 init1: 2206 opt: 2206 Z-score: 2591.1 bits: 487.7 E(91774): 1.5e-137
Smith-Waterman score: 2206; 100.0% identity (100.0% similar) in 321 aa overlap (1-321:1-321)
10 20 30 40 50 60
pF1KE2 MQEADISGYIPNGEWDLVGIPGKRSERFYECCKEPYPDVTFTVTMRRRTLYYGLNLLIPC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_683 MQEADISGYIPNGEWDLVGIPGKRSERFYECCKEPYPDVTFTVTMRRRTLYYGLNLLIPC
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 VLISALALLVFLLPADSGEKISLGITVLLSLTVFMLLVAEIMPATSDSVPLIAQYFASTM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_683 VLISALALLVFLLPADSGEKISLGITVLLSLTVFMLLVAEIMPATSDSVPLIAQYFASTM
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 IIVGLSVVVTVIVLQYHHHDPDGGKMPKWTRVILLNWCAWFLRMKRPGEDKVRPACQHKQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_683 IIVGLSVVVTVIVLQYHHHDPDGGKMPKWTRVILLNWCAWFLRMKRPGEDKVRPACQHKQ
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE2 RRCSLASVEMSAVAPPPASNGNLLYIGFRGLDGVHCVPTPDSGVVCGRMACSPTHDEHLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_683 RRCSLASVEMSAVAPPPASNGNLLYIGFRGLDGVHCVPTPDSGVVCGRMACSPTHDEHLL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE2 HGGQPPEGDPDLAKILEEVRYIANRFRCQDESEAVCSEWKFAACVVDRLCLMAFSVFTII
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_683 HGGQPPEGDPDLAKILEEVRYIANRFRCQDESEAVCSEWKFAACVVDRLCLMAFSVFTII
250 260 270 280 290 300
310 320
pF1KE2 CTIGILMSAPNFVEAVSKDFA
:::::::::::::::::::::
NP_683 CTIGILMSAPNFVEAVSKDFA
310 320
>>XP_011519479 (OMIM: 118511,612001) neuronal acetylchol (401 aa)
initn: 2206 init1: 2206 opt: 2206 Z-score: 2589.8 bits: 487.8 E(91774): 1.7e-137
Smith-Waterman score: 2206; 100.0% identity (100.0% similar) in 321 aa overlap (1-321:81-401)
10 20 30
pF1KE2 MQEADISGYIPNGEWDLVGIPGKRSERFYE
::::::::::::::::::::::::::::::
XP_011 IDVRWFPFDVQHCKLKFGSWSYGGWSLDLQMQEADISGYIPNGEWDLVGIPGKRSERFYE
60 70 80 90 100 110
40 50 60 70 80 90
pF1KE2 CCKEPYPDVTFTVTMRRRTLYYGLNLLIPCVLISALALLVFLLPADSGEKISLGITVLLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CCKEPYPDVTFTVTMRRRTLYYGLNLLIPCVLISALALLVFLLPADSGEKISLGITVLLS
120 130 140 150 160 170
100 110 120 130 140 150
pF1KE2 LTVFMLLVAEIMPATSDSVPLIAQYFASTMIIVGLSVVVTVIVLQYHHHDPDGGKMPKWT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LTVFMLLVAEIMPATSDSVPLIAQYFASTMIIVGLSVVVTVIVLQYHHHDPDGGKMPKWT
180 190 200 210 220 230
160 170 180 190 200 210
pF1KE2 RVILLNWCAWFLRMKRPGEDKVRPACQHKQRRCSLASVEMSAVAPPPASNGNLLYIGFRG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RVILLNWCAWFLRMKRPGEDKVRPACQHKQRRCSLASVEMSAVAPPPASNGNLLYIGFRG
240 250 260 270 280 290
220 230 240 250 260 270
pF1KE2 LDGVHCVPTPDSGVVCGRMACSPTHDEHLLHGGQPPEGDPDLAKILEEVRYIANRFRCQD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LDGVHCVPTPDSGVVCGRMACSPTHDEHLLHGGQPPEGDPDLAKILEEVRYIANRFRCQD
300 310 320 330 340 350
280 290 300 310 320
pF1KE2 ESEAVCSEWKFAACVVDRLCLMAFSVFTIICTIGILMSAPNFVEAVSKDFA
:::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ESEAVCSEWKFAACVVDRLCLMAFSVFTIICTIGILMSAPNFVEAVSKDFA
360 370 380 390 400
>>NP_647536 (OMIM: 609756) CHRNA7-FAM7A fusion protein i (412 aa)
initn: 2206 init1: 2206 opt: 2206 Z-score: 2589.7 bits: 487.8 E(91774): 1.8e-137
Smith-Waterman score: 2206; 100.0% identity (100.0% similar) in 321 aa overlap (1-321:92-412)
10 20 30
pF1KE2 MQEADISGYIPNGEWDLVGIPGKRSERFYE
::::::::::::::::::::::::::::::
NP_647 IDVRWFPFDVQHCKLKFGSWSYGGWSLDLQMQEADISGYIPNGEWDLVGIPGKRSERFYE
70 80 90 100 110 120
40 50 60 70 80 90
pF1KE2 CCKEPYPDVTFTVTMRRRTLYYGLNLLIPCVLISALALLVFLLPADSGEKISLGITVLLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_647 CCKEPYPDVTFTVTMRRRTLYYGLNLLIPCVLISALALLVFLLPADSGEKISLGITVLLS
130 140 150 160 170 180
100 110 120 130 140 150
pF1KE2 LTVFMLLVAEIMPATSDSVPLIAQYFASTMIIVGLSVVVTVIVLQYHHHDPDGGKMPKWT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_647 LTVFMLLVAEIMPATSDSVPLIAQYFASTMIIVGLSVVVTVIVLQYHHHDPDGGKMPKWT
190 200 210 220 230 240
160 170 180 190 200 210
pF1KE2 RVILLNWCAWFLRMKRPGEDKVRPACQHKQRRCSLASVEMSAVAPPPASNGNLLYIGFRG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_647 RVILLNWCAWFLRMKRPGEDKVRPACQHKQRRCSLASVEMSAVAPPPASNGNLLYIGFRG
250 260 270 280 290 300
220 230 240 250 260 270
pF1KE2 LDGVHCVPTPDSGVVCGRMACSPTHDEHLLHGGQPPEGDPDLAKILEEVRYIANRFRCQD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_647 LDGVHCVPTPDSGVVCGRMACSPTHDEHLLHGGQPPEGDPDLAKILEEVRYIANRFRCQD
310 320 330 340 350 360
280 290 300 310 320
pF1KE2 ESEAVCSEWKFAACVVDRLCLMAFSVFTIICTIGILMSAPNFVEAVSKDFA
:::::::::::::::::::::::::::::::::::::::::::::::::::
NP_647 ESEAVCSEWKFAACVVDRLCLMAFSVFTIICTIGILMSAPNFVEAVSKDFA
370 380 390 400 410
>>XP_011520455 (OMIM: 609756) CHRNA7-FAM7A fusion protei (412 aa)
initn: 2206 init1: 2206 opt: 2206 Z-score: 2589.7 bits: 487.8 E(91774): 1.8e-137
Smith-Waterman score: 2206; 100.0% identity (100.0% similar) in 321 aa overlap (1-321:92-412)
10 20 30
pF1KE2 MQEADISGYIPNGEWDLVGIPGKRSERFYE
::::::::::::::::::::::::::::::
XP_011 IDVRWFPFDVQHCKLKFGSWSYGGWSLDLQMQEADISGYIPNGEWDLVGIPGKRSERFYE
70 80 90 100 110 120
40 50 60 70 80 90
pF1KE2 CCKEPYPDVTFTVTMRRRTLYYGLNLLIPCVLISALALLVFLLPADSGEKISLGITVLLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CCKEPYPDVTFTVTMRRRTLYYGLNLLIPCVLISALALLVFLLPADSGEKISLGITVLLS
130 140 150 160 170 180
100 110 120 130 140 150
pF1KE2 LTVFMLLVAEIMPATSDSVPLIAQYFASTMIIVGLSVVVTVIVLQYHHHDPDGGKMPKWT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LTVFMLLVAEIMPATSDSVPLIAQYFASTMIIVGLSVVVTVIVLQYHHHDPDGGKMPKWT
190 200 210 220 230 240
160 170 180 190 200 210
pF1KE2 RVILLNWCAWFLRMKRPGEDKVRPACQHKQRRCSLASVEMSAVAPPPASNGNLLYIGFRG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RVILLNWCAWFLRMKRPGEDKVRPACQHKQRRCSLASVEMSAVAPPPASNGNLLYIGFRG
250 260 270 280 290 300
220 230 240 250 260 270
pF1KE2 LDGVHCVPTPDSGVVCGRMACSPTHDEHLLHGGQPPEGDPDLAKILEEVRYIANRFRCQD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LDGVHCVPTPDSGVVCGRMACSPTHDEHLLHGGQPPEGDPDLAKILEEVRYIANRFRCQD
310 320 330 340 350 360
280 290 300 310 320
pF1KE2 ESEAVCSEWKFAACVVDRLCLMAFSVFTIICTIGILMSAPNFVEAVSKDFA
:::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ESEAVCSEWKFAACVVDRLCLMAFSVFTIICTIGILMSAPNFVEAVSKDFA
370 380 390 400 410
>>XP_016877372 (OMIM: 118511,612001) neuronal acetylchol (440 aa)
initn: 2206 init1: 2206 opt: 2206 Z-score: 2589.3 bits: 487.8 E(91774): 1.9e-137
Smith-Waterman score: 2206; 100.0% identity (100.0% similar) in 321 aa overlap (1-321:120-440)
10 20 30
pF1KE2 MQEADISGYIPNGEWDLVGIPGKRSERFYE
::::::::::::::::::::::::::::::
XP_016 IDVRWFPFDVQHCKLKFGSWSYGGWSLDLQMQEADISGYIPNGEWDLVGIPGKRSERFYE
90 100 110 120 130 140
40 50 60 70 80 90
pF1KE2 CCKEPYPDVTFTVTMRRRTLYYGLNLLIPCVLISALALLVFLLPADSGEKISLGITVLLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CCKEPYPDVTFTVTMRRRTLYYGLNLLIPCVLISALALLVFLLPADSGEKISLGITVLLS
150 160 170 180 190 200
100 110 120 130 140 150
pF1KE2 LTVFMLLVAEIMPATSDSVPLIAQYFASTMIIVGLSVVVTVIVLQYHHHDPDGGKMPKWT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LTVFMLLVAEIMPATSDSVPLIAQYFASTMIIVGLSVVVTVIVLQYHHHDPDGGKMPKWT
210 220 230 240 250 260
160 170 180 190 200 210
pF1KE2 RVILLNWCAWFLRMKRPGEDKVRPACQHKQRRCSLASVEMSAVAPPPASNGNLLYIGFRG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RVILLNWCAWFLRMKRPGEDKVRPACQHKQRRCSLASVEMSAVAPPPASNGNLLYIGFRG
270 280 290 300 310 320
220 230 240 250 260 270
pF1KE2 LDGVHCVPTPDSGVVCGRMACSPTHDEHLLHGGQPPEGDPDLAKILEEVRYIANRFRCQD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LDGVHCVPTPDSGVVCGRMACSPTHDEHLLHGGQPPEGDPDLAKILEEVRYIANRFRCQD
330 340 350 360 370 380
280 290 300 310 320
pF1KE2 ESEAVCSEWKFAACVVDRLCLMAFSVFTIICTIGILMSAPNFVEAVSKDFA
:::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ESEAVCSEWKFAACVVDRLCLMAFSVFTIICTIGILMSAPNFVEAVSKDFA
390 400 410 420 430 440
>>XP_016877371 (OMIM: 118511,612001) neuronal acetylchol (441 aa)
initn: 2206 init1: 2206 opt: 2206 Z-score: 2589.3 bits: 487.8 E(91774): 1.9e-137
Smith-Waterman score: 2206; 100.0% identity (100.0% similar) in 321 aa overlap (1-321:121-441)
10 20 30
pF1KE2 MQEADISGYIPNGEWDLVGIPGKRSERFYE
::::::::::::::::::::::::::::::
XP_016 IDVRWFPFDVQHCKLKFGSWSYGGWSLDLQMQEADISGYIPNGEWDLVGIPGKRSERFYE
100 110 120 130 140 150
40 50 60 70 80 90
pF1KE2 CCKEPYPDVTFTVTMRRRTLYYGLNLLIPCVLISALALLVFLLPADSGEKISLGITVLLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CCKEPYPDVTFTVTMRRRTLYYGLNLLIPCVLISALALLVFLLPADSGEKISLGITVLLS
160 170 180 190 200 210
100 110 120 130 140 150
pF1KE2 LTVFMLLVAEIMPATSDSVPLIAQYFASTMIIVGLSVVVTVIVLQYHHHDPDGGKMPKWT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LTVFMLLVAEIMPATSDSVPLIAQYFASTMIIVGLSVVVTVIVLQYHHHDPDGGKMPKWT
220 230 240 250 260 270
160 170 180 190 200 210
pF1KE2 RVILLNWCAWFLRMKRPGEDKVRPACQHKQRRCSLASVEMSAVAPPPASNGNLLYIGFRG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RVILLNWCAWFLRMKRPGEDKVRPACQHKQRRCSLASVEMSAVAPPPASNGNLLYIGFRG
280 290 300 310 320 330
220 230 240 250 260 270
pF1KE2 LDGVHCVPTPDSGVVCGRMACSPTHDEHLLHGGQPPEGDPDLAKILEEVRYIANRFRCQD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LDGVHCVPTPDSGVVCGRMACSPTHDEHLLHGGQPPEGDPDLAKILEEVRYIANRFRCQD
340 350 360 370 380 390
280 290 300 310 320
pF1KE2 ESEAVCSEWKFAACVVDRLCLMAFSVFTIICTIGILMSAPNFVEAVSKDFA
:::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ESEAVCSEWKFAACVVDRLCLMAFSVFTIICTIGILMSAPNFVEAVSKDFA
400 410 420 430 440
>>XP_011519478 (OMIM: 118511,612001) neuronal acetylchol (486 aa)
initn: 2206 init1: 2206 opt: 2206 Z-score: 2588.7 bits: 487.8 E(91774): 2e-137
Smith-Waterman score: 2206; 100.0% identity (100.0% similar) in 321 aa overlap (1-321:166-486)
10 20 30
pF1KE2 MQEADISGYIPNGEWDLVGIPGKRSERFYE
::::::::::::::::::::::::::::::
XP_011 IDVRWFPFDVQHCKLKFGSWSYGGWSLDLQMQEADISGYIPNGEWDLVGIPGKRSERFYE
140 150 160 170 180 190
40 50 60 70 80 90
pF1KE2 CCKEPYPDVTFTVTMRRRTLYYGLNLLIPCVLISALALLVFLLPADSGEKISLGITVLLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CCKEPYPDVTFTVTMRRRTLYYGLNLLIPCVLISALALLVFLLPADSGEKISLGITVLLS
200 210 220 230 240 250
100 110 120 130 140 150
pF1KE2 LTVFMLLVAEIMPATSDSVPLIAQYFASTMIIVGLSVVVTVIVLQYHHHDPDGGKMPKWT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LTVFMLLVAEIMPATSDSVPLIAQYFASTMIIVGLSVVVTVIVLQYHHHDPDGGKMPKWT
260 270 280 290 300 310
160 170 180 190 200 210
pF1KE2 RVILLNWCAWFLRMKRPGEDKVRPACQHKQRRCSLASVEMSAVAPPPASNGNLLYIGFRG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RVILLNWCAWFLRMKRPGEDKVRPACQHKQRRCSLASVEMSAVAPPPASNGNLLYIGFRG
320 330 340 350 360 370
220 230 240 250 260 270
pF1KE2 LDGVHCVPTPDSGVVCGRMACSPTHDEHLLHGGQPPEGDPDLAKILEEVRYIANRFRCQD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LDGVHCVPTPDSGVVCGRMACSPTHDEHLLHGGQPPEGDPDLAKILEEVRYIANRFRCQD
380 390 400 410 420 430
280 290 300 310 320
pF1KE2 ESEAVCSEWKFAACVVDRLCLMAFSVFTIICTIGILMSAPNFVEAVSKDFA
:::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ESEAVCSEWKFAACVVDRLCLMAFSVFTIICTIGILMSAPNFVEAVSKDFA
440 450 460 470 480
>>NP_000737 (OMIM: 118511,612001) neuronal acetylcholine (502 aa)
initn: 2206 init1: 2206 opt: 2206 Z-score: 2588.5 bits: 487.8 E(91774): 2.1e-137
Smith-Waterman score: 2206; 100.0% identity (100.0% similar) in 321 aa overlap (1-321:182-502)
10 20 30
pF1KE2 MQEADISGYIPNGEWDLVGIPGKRSERFYE
::::::::::::::::::::::::::::::
NP_000 IDVRWFPFDVQHCKLKFGSWSYGGWSLDLQMQEADISGYIPNGEWDLVGIPGKRSERFYE
160 170 180 190 200 210
40 50 60 70 80 90
pF1KE2 CCKEPYPDVTFTVTMRRRTLYYGLNLLIPCVLISALALLVFLLPADSGEKISLGITVLLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 CCKEPYPDVTFTVTMRRRTLYYGLNLLIPCVLISALALLVFLLPADSGEKISLGITVLLS
220 230 240 250 260 270
100 110 120 130 140 150
pF1KE2 LTVFMLLVAEIMPATSDSVPLIAQYFASTMIIVGLSVVVTVIVLQYHHHDPDGGKMPKWT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 LTVFMLLVAEIMPATSDSVPLIAQYFASTMIIVGLSVVVTVIVLQYHHHDPDGGKMPKWT
280 290 300 310 320 330
160 170 180 190 200 210
pF1KE2 RVILLNWCAWFLRMKRPGEDKVRPACQHKQRRCSLASVEMSAVAPPPASNGNLLYIGFRG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 RVILLNWCAWFLRMKRPGEDKVRPACQHKQRRCSLASVEMSAVAPPPASNGNLLYIGFRG
340 350 360 370 380 390
220 230 240 250 260 270
pF1KE2 LDGVHCVPTPDSGVVCGRMACSPTHDEHLLHGGQPPEGDPDLAKILEEVRYIANRFRCQD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 LDGVHCVPTPDSGVVCGRMACSPTHDEHLLHGGQPPEGDPDLAKILEEVRYIANRFRCQD
400 410 420 430 440 450
280 290 300 310 320
pF1KE2 ESEAVCSEWKFAACVVDRLCLMAFSVFTIICTIGILMSAPNFVEAVSKDFA
:::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 ESEAVCSEWKFAACVVDRLCLMAFSVFTIICTIGILMSAPNFVEAVSKDFA
460 470 480 490 500
321 residues in 1 query sequences
64092750 residues in 91774 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Tue Jul 16 16:07:17 2019 done: Tue Jul 16 16:07:18 2019
Total Scan time: 3.710 Total Display time: 0.050
Function used was FASTA [36.3.4 Apr, 2011]