Result of FASTA (omim) for
pFN21AE2370
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE2370, 173 aa
1>>>pF1KE2370 173 - 173 aa - 173 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 4.9557+/-0.000314; mu= 14.6546+/- 0.020
mean_var=60.9296+/-12.386, 0's: 0 Z-trim(115.6): 16 B-trim: 0 in 0/49
Lambda= 0.164309
statistics sampled from 26114 (26130) to 26114 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.707), E-opt: 0.2 (0.306), width: 16
Scan time: 5.560
The best scores are: opt bits E(85289)
NP_000385 (OMIM: 123580,604219) alpha-crystallin A ( 173) 1178 287.1 9.4e-78
XP_005261150 (OMIM: 123580,604219) PREDICTED: alph ( 136) 745 184.4 6.1e-47
NP_001276736 (OMIM: 123590,608810,613763,613869,61 ( 175) 657 163.6 1.4e-40
XP_011540910 (OMIM: 123590,608810,613763,613869,61 ( 175) 657 163.6 1.4e-40
NP_001876 (OMIM: 123590,608810,613763,613869,61518 ( 175) 657 163.6 1.4e-40
NP_001276737 (OMIM: 123590,608810,613763,613869,61 ( 175) 657 163.6 1.4e-40
NP_653218 (OMIM: 610695) heat shock protein beta-6 ( 160) 437 111.4 6.7e-25
NP_001317308 (OMIM: 123590,608810,613763,613869,61 ( 108) 431 109.9 1.3e-24
NP_001531 (OMIM: 602195,606595,608634) heat shock ( 205) 360 93.3 2.5e-19
NP_001532 (OMIM: 602179) heat shock protein beta-2 ( 182) 324 84.7 8.6e-17
NP_006299 (OMIM: 604624,613376) heat shock protein ( 150) 216 59.0 3.7e-09
NP_055180 (OMIM: 158590,608014,608673) heat shock ( 196) 215 58.9 5.5e-09
XP_011539551 (OMIM: 610692) PREDICTED: heat shock ( 263) 162 46.4 4.2e-05
NP_149971 (OMIM: 608344) heat shock protein beta-9 ( 159) 156 44.8 7.5e-05
XP_011539552 (OMIM: 610692) PREDICTED: heat shock ( 262) 152 44.0 0.00022
NP_055239 (OMIM: 610692) heat shock protein beta-7 ( 170) 149 43.2 0.00025
>>NP_000385 (OMIM: 123580,604219) alpha-crystallin A cha (173 aa)
initn: 1178 init1: 1178 opt: 1178 Z-score: 1516.9 bits: 287.1 E(85289): 9.4e-78
Smith-Waterman score: 1178; 100.0% identity (100.0% similar) in 173 aa overlap (1-173:1-173)
10 20 30 40 50 60
pF1KE2 MDVTIQHPWFKRTLGPFYPSRLFDQFFGEGLFEYDLLPFLSSTISPYYRQSLFRTVLDSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 MDVTIQHPWFKRTLGPFYPSRLFDQFFGEGLFEYDLLPFLSSTISPYYRQSLFRTVLDSG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 ISEVRSDRDKFVIFLDVKHFSPEDLTVKVQDDFVEIHGKHNERQDDHGYISREFHRRYRL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 ISEVRSDRDKFVIFLDVKHFSPEDLTVKVQDDFVEIHGKHNERQDDHGYISREFHRRYRL
70 80 90 100 110 120
130 140 150 160 170
pF1KE2 PSNVDQSALSCSLSADGMLTFCGPKIQTGLDATHAERAIPVSREEKPTSAPSS
:::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 PSNVDQSALSCSLSADGMLTFCGPKIQTGLDATHAERAIPVSREEKPTSAPSS
130 140 150 160 170
>>XP_005261150 (OMIM: 123580,604219) PREDICTED: alpha-cr (136 aa)
initn: 745 init1: 745 opt: 745 Z-score: 963.7 bits: 184.4 E(85289): 6.1e-47
Smith-Waterman score: 745; 99.1% identity (100.0% similar) in 111 aa overlap (63-173:26-136)
40 50 60 70 80 90
pF1KE2 EYDLLPFLSSTISPYYRQSLFRTVLDSGISEVRSDRDKFVIFLDVKHFSPEDLTVKVQDD
.:::::::::::::::::::::::::::::
XP_005 MPVCPGDSHRPPKALPHLVCGRRGRQVRSDRDKFVIFLDVKHFSPEDLTVKVQDD
10 20 30 40 50
100 110 120 130 140 150
pF1KE2 FVEIHGKHNERQDDHGYISREFHRRYRLPSNVDQSALSCSLSADGMLTFCGPKIQTGLDA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 FVEIHGKHNERQDDHGYISREFHRRYRLPSNVDQSALSCSLSADGMLTFCGPKIQTGLDA
60 70 80 90 100 110
160 170
pF1KE2 THAERAIPVSREEKPTSAPSS
:::::::::::::::::::::
XP_005 THAERAIPVSREEKPTSAPSS
120 130
>>NP_001276736 (OMIM: 123590,608810,613763,613869,615184 (175 aa)
initn: 504 init1: 406 opt: 657 Z-score: 849.3 bits: 163.6 E(85289): 1.4e-40
Smith-Waterman score: 657; 54.5% identity (80.9% similar) in 178 aa overlap (1-171:1-173)
10 20 30 40 50
pF1KE2 MDVTIQHPWFKRTLGPFY-PSRLFDQFFGEGLFEYDLLPFLSSTISPYYRQ--SLFR--T
::..:.:::..: . ::. ::::::::::: :.: ::.: :...::.: . :..: .
NP_001 MDIAIHHPWIRRPFFPFHSPSRLFDQFFGEHLLESDLFP-TSTSLSPFYLRPPSFLRAPS
10 20 30 40 50
60 70 80 90 100 110
pF1KE2 VLDSGISEVRSDRDKFVIFLDVKHFSPEDLTVKVQDDFVEIHGKHNERQDDHGYISREFH
.:.:.::.: ..:.: . :::::::::.: ::: : .:.::::.::::.::.::::::
NP_001 WFDTGLSEMRLEKDRFSVNLDVKHFSPEELKVKVLGDVIEVHGKHEERQDEHGFISREFH
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE2 RRYRLPSNVDQSALSCSLSADGMLTFCGPKIQTGLDATHAERAIPVSREEKP--TSAPSS
:.::.:..:: ... :::.::.:: ::. :. . ::.::..::::: :.::
NP_001 RKYRIPADVDPLTITSSLSSDGVLTVNGPRKQV----SGPERTIPITREEKPAVTAAPKK
120 130 140 150 160 170
>>XP_011540910 (OMIM: 123590,608810,613763,613869,615184 (175 aa)
initn: 504 init1: 406 opt: 657 Z-score: 849.3 bits: 163.6 E(85289): 1.4e-40
Smith-Waterman score: 657; 54.5% identity (80.9% similar) in 178 aa overlap (1-171:1-173)
10 20 30 40 50
pF1KE2 MDVTIQHPWFKRTLGPFY-PSRLFDQFFGEGLFEYDLLPFLSSTISPYYRQ--SLFR--T
::..:.:::..: . ::. ::::::::::: :.: ::.: :...::.: . :..: .
XP_011 MDIAIHHPWIRRPFFPFHSPSRLFDQFFGEHLLESDLFP-TSTSLSPFYLRPPSFLRAPS
10 20 30 40 50
60 70 80 90 100 110
pF1KE2 VLDSGISEVRSDRDKFVIFLDVKHFSPEDLTVKVQDDFVEIHGKHNERQDDHGYISREFH
.:.:.::.: ..:.: . :::::::::.: ::: : .:.::::.::::.::.::::::
XP_011 WFDTGLSEMRLEKDRFSVNLDVKHFSPEELKVKVLGDVIEVHGKHEERQDEHGFISREFH
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE2 RRYRLPSNVDQSALSCSLSADGMLTFCGPKIQTGLDATHAERAIPVSREEKP--TSAPSS
:.::.:..:: ... :::.::.:: ::. :. . ::.::..::::: :.::
XP_011 RKYRIPADVDPLTITSSLSSDGVLTVNGPRKQV----SGPERTIPITREEKPAVTAAPKK
120 130 140 150 160 170
>>NP_001876 (OMIM: 123590,608810,613763,613869,615184) a (175 aa)
initn: 504 init1: 406 opt: 657 Z-score: 849.3 bits: 163.6 E(85289): 1.4e-40
Smith-Waterman score: 657; 54.5% identity (80.9% similar) in 178 aa overlap (1-171:1-173)
10 20 30 40 50
pF1KE2 MDVTIQHPWFKRTLGPFY-PSRLFDQFFGEGLFEYDLLPFLSSTISPYYRQ--SLFR--T
::..:.:::..: . ::. ::::::::::: :.: ::.: :...::.: . :..: .
NP_001 MDIAIHHPWIRRPFFPFHSPSRLFDQFFGEHLLESDLFP-TSTSLSPFYLRPPSFLRAPS
10 20 30 40 50
60 70 80 90 100 110
pF1KE2 VLDSGISEVRSDRDKFVIFLDVKHFSPEDLTVKVQDDFVEIHGKHNERQDDHGYISREFH
.:.:.::.: ..:.: . :::::::::.: ::: : .:.::::.::::.::.::::::
NP_001 WFDTGLSEMRLEKDRFSVNLDVKHFSPEELKVKVLGDVIEVHGKHEERQDEHGFISREFH
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE2 RRYRLPSNVDQSALSCSLSADGMLTFCGPKIQTGLDATHAERAIPVSREEKP--TSAPSS
:.::.:..:: ... :::.::.:: ::. :. . ::.::..::::: :.::
NP_001 RKYRIPADVDPLTITSSLSSDGVLTVNGPRKQV----SGPERTIPITREEKPAVTAAPKK
120 130 140 150 160 170
>>NP_001276737 (OMIM: 123590,608810,613763,613869,615184 (175 aa)
initn: 504 init1: 406 opt: 657 Z-score: 849.3 bits: 163.6 E(85289): 1.4e-40
Smith-Waterman score: 657; 54.5% identity (80.9% similar) in 178 aa overlap (1-171:1-173)
10 20 30 40 50
pF1KE2 MDVTIQHPWFKRTLGPFY-PSRLFDQFFGEGLFEYDLLPFLSSTISPYYRQ--SLFR--T
::..:.:::..: . ::. ::::::::::: :.: ::.: :...::.: . :..: .
NP_001 MDIAIHHPWIRRPFFPFHSPSRLFDQFFGEHLLESDLFP-TSTSLSPFYLRPPSFLRAPS
10 20 30 40 50
60 70 80 90 100 110
pF1KE2 VLDSGISEVRSDRDKFVIFLDVKHFSPEDLTVKVQDDFVEIHGKHNERQDDHGYISREFH
.:.:.::.: ..:.: . :::::::::.: ::: : .:.::::.::::.::.::::::
NP_001 WFDTGLSEMRLEKDRFSVNLDVKHFSPEELKVKVLGDVIEVHGKHEERQDEHGFISREFH
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE2 RRYRLPSNVDQSALSCSLSADGMLTFCGPKIQTGLDATHAERAIPVSREEKP--TSAPSS
:.::.:..:: ... :::.::.:: ::. :. . ::.::..::::: :.::
NP_001 RKYRIPADVDPLTITSSLSSDGVLTVNGPRKQV----SGPERTIPITREEKPAVTAAPKK
120 130 140 150 160 170
>>NP_653218 (OMIM: 610695) heat shock protein beta-6 [Ho (160 aa)
initn: 395 init1: 289 opt: 437 Z-score: 568.1 bits: 111.4 E(85289): 6.7e-25
Smith-Waterman score: 437; 44.4% identity (73.6% similar) in 144 aa overlap (1-140:3-143)
10 20 30 40 50
pF1KE2 MDVTIQHPWFKRTLGPF----YPSRLFDQFFGEGLFEYDLLPFLSSTISPYYRQSLFR
. : .: :..:. .:. :.::::: :::::.: .: . .:..::: :
NP_653 MEIPVPVQPSWLRRASAPLPGLSAPGRLFDQRFGEGLLEAELAALCPTTLAPYY---LRA
10 20 30 40 50
60 70 80 90 100 110
pF1KE2 TVLDSGISEVRSDRDKFVIFLDVKHFSPEDLTVKVQDDFVEIHGKHNERQDDHGYISREF
. ...: .: .: ..:::::::::...::: . ::.:..:.:: :.::...:::
NP_653 PSVALPVAQVPTDPGHFSVLLDVKHFSPEEIAVKVVGEHVEVHARHEERPDEHGFVAREF
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE2 HRRYRLPSNVDQSALSCSLSADGMLTFCGPKIQTGLDATHAERAIPVSREEKPTSAPSS
::::::: .:: .:.. .:: .:.:.
NP_653 HRRYRLPPGVDPAAVTSALSPEGVLSIQAAPASAQAPPPAAAK
120 130 140 150 160
>>NP_001317308 (OMIM: 123590,608810,613763,613869,615184 (108 aa)
initn: 402 init1: 347 opt: 431 Z-score: 562.9 bits: 109.9 E(85289): 1.3e-24
Smith-Waterman score: 431; 56.4% identity (80.9% similar) in 110 aa overlap (64-171:1-106)
40 50 60 70 80 90
pF1KE2 YDLLPFLSSTISPYYRQSLFRTVLDSGISEVRSDRDKFVIFLDVKHFSPEDLTVKVQDDF
.: ..:.: . :::::::::.: ::: :
NP_001 MRLEKDRFSVNLDVKHFSPEELKVKVLGDV
10 20 30
100 110 120 130 140 150
pF1KE2 VEIHGKHNERQDDHGYISREFHRRYRLPSNVDQSALSCSLSADGMLTFCGPKIQTGLDAT
.:.::::.::::.::.:::::::.::.:..:: ... :::.::.:: ::. :. .
NP_001 IEVHGKHEERQDEHGFISREFHRKYRIPADVDPLTITSSLSSDGVLTVNGPRKQV----S
40 50 60 70 80
160 170
pF1KE2 HAERAIPVSREEKP--TSAPSS
::.::..::::: :.::
NP_001 GPERTIPITREEKPAVTAAPKK
90 100
>>NP_001531 (OMIM: 602195,606595,608634) heat shock prot (205 aa)
initn: 382 init1: 327 opt: 360 Z-score: 467.9 bits: 93.3 E(85289): 2.5e-19
Smith-Waterman score: 364; 41.4% identity (60.9% similar) in 174 aa overlap (16-166:18-188)
10 20 30 40
pF1KE2 MDVTIQHPWFKRTLGPF---YP-SRLFDQFFGEGLFEYDLLPFLSST-----------
:: :: :::::: :: . . .:...
NP_001 MTERRVPFSLLRGPSWDPFRDWYPHSRLFDQAFGLPRLPEEWSQWLGGSSWPGYVRPLPP
10 20 30 40 50 60
50 60 70 80 90
pF1KE2 --------ISPYYRQSLFRTVLDSGISEVRSDRDKFVIFLDVKHFSPEDLTVKVQDDFVE
.: : ..: : :.::.::.: :.. . :::.::.:..::::..: ::
NP_001 AAIESPAVAAPAYSRALSRQ-LSSGVSEIRHTADRWRVSLDVNHFAPDELTVKTKDGVVE
70 80 90 100 110
100 110 120 130 140 150
pF1KE2 IHGKHNERQDDHGYISREFHRRYRLPSNVDQSALSCSLSADGMLTFCGPKIQTGLDATHA
: :::.::::.:::::: : :.: :: .:: . .: ::: .: :: .: . : .
NP_001 ITGKHEERQDEHGYISRCFTRKYTLPPGVDPTQVSSSLSPEGTLTVEAPMPK--LATQSN
120 130 140 150 160 170
160 170
pF1KE2 ERAIPVSREEKPTSAPSS
: .:::. : .
NP_001 EITIPVTFESRAQLGGPEAAKSDETAAK
180 190 200
>>NP_001532 (OMIM: 602179) heat shock protein beta-2 [Ho (182 aa)
initn: 336 init1: 279 opt: 324 Z-score: 422.5 bits: 84.7 E(85289): 8.6e-17
Smith-Waterman score: 324; 38.0% identity (62.0% similar) in 158 aa overlap (19-170:21-178)
10 20 30 40 50
pF1KE2 MDVTIQHPWFKRTLGPFYPSRLFDQFFGEGLFEYDLL-PFLSSTISPYYRQSLFRTVL
:::: .: :::::. ..: : : : .
NP_001 MSGRSVPHAHPATAEYEFANPSRLGEQRFGEGLLPEEILTPTLYHGYYVRPRAAPAGEGS
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE2 DSGISEVRSDRDKFVIFLDVKHFSPEDLTVKVQDDFVEIHGKHNERQDDHGYISREFHRR
.: ::.: .. :: ::::.::.:...::.. :...:. ..: .: : ::..:::: :
NP_001 RAGASELRLSEGKFQAFLDVSHFTPDEVTVRTVDNLLEVSARHPQRLDRHGFVSREFCRT
70 80 90 100 110 120
120 130 140 150 160 170
pF1KE2 YRLPSNVDQSALSCSLSADGMLTFCGPKIQTGLDATHAERAI-----PVSREEKPTSAPS
: ::..:: . .:: ::.:.. .:. ::. : : : . ::. .:
NP_001 YVLPADVDPWRVRAALSHDGILNLEAPRGGRHLDTEVNEVYISLLPAPPDPEEEEEAAIV
130 140 150 160 170 180
pF1KE2 S
NP_001 EP
173 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 12:58:05 2016 done: Sun Nov 6 12:58:06 2016
Total Scan time: 5.560 Total Display time: -0.020
Function used was FASTA [36.3.4 Apr, 2011]