Result of FASTA (ccds) for
pFN21AE2370
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE2370, 173 aa
1>>>pF1KE2370 173 - 173 aa - 173 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.5686+/-0.00069; mu= 10.7540+/- 0.041
mean_var=56.5042+/-11.458, 0's: 0 Z-trim(108.8): 14 B-trim: 0 in 0/50
Lambda= 0.170622
statistics sampled from 10468 (10480) to 10468 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.723), E-opt: 0.2 (0.322), width: 16
Scan time: 1.900
The best scores are: opt bits E(32554)
CCDS13695.1 CRYAA gene_id:1409|Hs108|chr21 ( 173) 1178 297.6 2.5e-81
CCDS82651.1 LOC102724652 gene_id:102724652|Hs108|c ( 173) 1178 297.6 2.5e-81
CCDS82652.1 LOC102724652 gene_id:102724652|Hs108|c ( 136) 745 191.0 2.4e-49
CCDS8351.1 CRYAB gene_id:1410|Hs108|chr11 ( 175) 657 169.4 1e-42
CCDS12475.1 HSPB6 gene_id:126393|Hs108|chr19 ( 160) 437 115.2 1.9e-26
CCDS81626.1 CRYAB gene_id:1410|Hs108|chr11 ( 108) 431 113.7 3.6e-26
CCDS5583.1 HSPB1 gene_id:3315|Hs108|chr7 ( 205) 360 96.3 1.2e-20
CCDS8352.1 HSPB2 gene_id:3316|Hs108|chr11 ( 182) 324 87.4 5.1e-18
>>CCDS13695.1 CRYAA gene_id:1409|Hs108|chr21 (173 aa)
initn: 1178 init1: 1178 opt: 1178 Z-score: 1573.5 bits: 297.6 E(32554): 2.5e-81
Smith-Waterman score: 1178; 100.0% identity (100.0% similar) in 173 aa overlap (1-173:1-173)
10 20 30 40 50 60
pF1KE2 MDVTIQHPWFKRTLGPFYPSRLFDQFFGEGLFEYDLLPFLSSTISPYYRQSLFRTVLDSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS13 MDVTIQHPWFKRTLGPFYPSRLFDQFFGEGLFEYDLLPFLSSTISPYYRQSLFRTVLDSG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 ISEVRSDRDKFVIFLDVKHFSPEDLTVKVQDDFVEIHGKHNERQDDHGYISREFHRRYRL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS13 ISEVRSDRDKFVIFLDVKHFSPEDLTVKVQDDFVEIHGKHNERQDDHGYISREFHRRYRL
70 80 90 100 110 120
130 140 150 160 170
pF1KE2 PSNVDQSALSCSLSADGMLTFCGPKIQTGLDATHAERAIPVSREEKPTSAPSS
:::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS13 PSNVDQSALSCSLSADGMLTFCGPKIQTGLDATHAERAIPVSREEKPTSAPSS
130 140 150 160 170
>>CCDS82651.1 LOC102724652 gene_id:102724652|Hs108|chr21 (173 aa)
initn: 1178 init1: 1178 opt: 1178 Z-score: 1573.5 bits: 297.6 E(32554): 2.5e-81
Smith-Waterman score: 1178; 100.0% identity (100.0% similar) in 173 aa overlap (1-173:1-173)
10 20 30 40 50 60
pF1KE2 MDVTIQHPWFKRTLGPFYPSRLFDQFFGEGLFEYDLLPFLSSTISPYYRQSLFRTVLDSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS82 MDVTIQHPWFKRTLGPFYPSRLFDQFFGEGLFEYDLLPFLSSTISPYYRQSLFRTVLDSG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 ISEVRSDRDKFVIFLDVKHFSPEDLTVKVQDDFVEIHGKHNERQDDHGYISREFHRRYRL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS82 ISEVRSDRDKFVIFLDVKHFSPEDLTVKVQDDFVEIHGKHNERQDDHGYISREFHRRYRL
70 80 90 100 110 120
130 140 150 160 170
pF1KE2 PSNVDQSALSCSLSADGMLTFCGPKIQTGLDATHAERAIPVSREEKPTSAPSS
:::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS82 PSNVDQSALSCSLSADGMLTFCGPKIQTGLDATHAERAIPVSREEKPTSAPSS
130 140 150 160 170
>>CCDS82652.1 LOC102724652 gene_id:102724652|Hs108|chr21 (136 aa)
initn: 745 init1: 745 opt: 745 Z-score: 999.2 bits: 191.0 E(32554): 2.4e-49
Smith-Waterman score: 745; 99.1% identity (100.0% similar) in 111 aa overlap (63-173:26-136)
40 50 60 70 80 90
pF1KE2 EYDLLPFLSSTISPYYRQSLFRTVLDSGISEVRSDRDKFVIFLDVKHFSPEDLTVKVQDD
.:::::::::::::::::::::::::::::
CCDS82 MPVCPGDSHRPPKALPHLVCGRRGRQVRSDRDKFVIFLDVKHFSPEDLTVKVQDD
10 20 30 40 50
100 110 120 130 140 150
pF1KE2 FVEIHGKHNERQDDHGYISREFHRRYRLPSNVDQSALSCSLSADGMLTFCGPKIQTGLDA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS82 FVEIHGKHNERQDDHGYISREFHRRYRLPSNVDQSALSCSLSADGMLTFCGPKIQTGLDA
60 70 80 90 100 110
160 170
pF1KE2 THAERAIPVSREEKPTSAPSS
:::::::::::::::::::::
CCDS82 THAERAIPVSREEKPTSAPSS
120 130
>>CCDS8351.1 CRYAB gene_id:1410|Hs108|chr11 (175 aa)
initn: 504 init1: 406 opt: 657 Z-score: 880.3 bits: 169.4 E(32554): 1e-42
Smith-Waterman score: 657; 54.5% identity (80.9% similar) in 178 aa overlap (1-171:1-173)
10 20 30 40 50
pF1KE2 MDVTIQHPWFKRTLGPFY-PSRLFDQFFGEGLFEYDLLPFLSSTISPYYRQ--SLFR--T
::..:.:::..: . ::. ::::::::::: :.: ::.: :...::.: . :..: .
CCDS83 MDIAIHHPWIRRPFFPFHSPSRLFDQFFGEHLLESDLFP-TSTSLSPFYLRPPSFLRAPS
10 20 30 40 50
60 70 80 90 100 110
pF1KE2 VLDSGISEVRSDRDKFVIFLDVKHFSPEDLTVKVQDDFVEIHGKHNERQDDHGYISREFH
.:.:.::.: ..:.: . :::::::::.: ::: : .:.::::.::::.::.::::::
CCDS83 WFDTGLSEMRLEKDRFSVNLDVKHFSPEELKVKVLGDVIEVHGKHEERQDEHGFISREFH
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE2 RRYRLPSNVDQSALSCSLSADGMLTFCGPKIQTGLDATHAERAIPVSREEKP--TSAPSS
:.::.:..:: ... :::.::.:: ::. :. . ::.::..::::: :.::
CCDS83 RKYRIPADVDPLTITSSLSSDGVLTVNGPRKQV----SGPERTIPITREEKPAVTAAPKK
120 130 140 150 160 170
>>CCDS12475.1 HSPB6 gene_id:126393|Hs108|chr19 (160 aa)
initn: 395 init1: 289 opt: 437 Z-score: 588.3 bits: 115.2 E(32554): 1.9e-26
Smith-Waterman score: 437; 44.4% identity (73.6% similar) in 144 aa overlap (1-140:3-143)
10 20 30 40 50
pF1KE2 MDVTIQHPWFKRTLGPF----YPSRLFDQFFGEGLFEYDLLPFLSSTISPYYRQSLFR
. : .: :..:. .:. :.::::: :::::.: .: . .:..::: :
CCDS12 MEIPVPVQPSWLRRASAPLPGLSAPGRLFDQRFGEGLLEAELAALCPTTLAPYY---LRA
10 20 30 40 50
60 70 80 90 100 110
pF1KE2 TVLDSGISEVRSDRDKFVIFLDVKHFSPEDLTVKVQDDFVEIHGKHNERQDDHGYISREF
. ...: .: .: ..:::::::::...::: . ::.:..:.:: :.::...:::
CCDS12 PSVALPVAQVPTDPGHFSVLLDVKHFSPEEIAVKVVGEHVEVHARHEERPDEHGFVAREF
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE2 HRRYRLPSNVDQSALSCSLSADGMLTFCGPKIQTGLDATHAERAIPVSREEKPTSAPSS
::::::: .:: .:.. .:: .:.:.
CCDS12 HRRYRLPPGVDPAAVTSALSPEGVLSIQAAPASAQAPPPAAAK
120 130 140 150 160
>>CCDS81626.1 CRYAB gene_id:1410|Hs108|chr11 (108 aa)
initn: 402 init1: 347 opt: 431 Z-score: 583.2 bits: 113.7 E(32554): 3.6e-26
Smith-Waterman score: 431; 56.4% identity (80.9% similar) in 110 aa overlap (64-171:1-106)
40 50 60 70 80 90
pF1KE2 YDLLPFLSSTISPYYRQSLFRTVLDSGISEVRSDRDKFVIFLDVKHFSPEDLTVKVQDDF
.: ..:.: . :::::::::.: ::: :
CCDS81 MRLEKDRFSVNLDVKHFSPEELKVKVLGDV
10 20 30
100 110 120 130 140 150
pF1KE2 VEIHGKHNERQDDHGYISREFHRRYRLPSNVDQSALSCSLSADGMLTFCGPKIQTGLDAT
.:.::::.::::.::.:::::::.::.:..:: ... :::.::.:: ::. :. .
CCDS81 IEVHGKHEERQDEHGFISREFHRKYRIPADVDPLTITSSLSSDGVLTVNGPRKQV----S
40 50 60 70 80
160 170
pF1KE2 HAERAIPVSREEKP--TSAPSS
::.::..::::: :.::
CCDS81 GPERTIPITREEKPAVTAAPKK
90 100
>>CCDS5583.1 HSPB1 gene_id:3315|Hs108|chr7 (205 aa)
initn: 382 init1: 327 opt: 360 Z-score: 484.0 bits: 96.3 E(32554): 1.2e-20
Smith-Waterman score: 364; 41.4% identity (60.9% similar) in 174 aa overlap (16-166:18-188)
10 20 30 40
pF1KE2 MDVTIQHPWFKRTLGPF---YP-SRLFDQFFGEGLFEYDLLPFLSST-----------
:: :: :::::: :: . . .:...
CCDS55 MTERRVPFSLLRGPSWDPFRDWYPHSRLFDQAFGLPRLPEEWSQWLGGSSWPGYVRPLPP
10 20 30 40 50 60
50 60 70 80 90
pF1KE2 --------ISPYYRQSLFRTVLDSGISEVRSDRDKFVIFLDVKHFSPEDLTVKVQDDFVE
.: : ..: : :.::.::.: :.. . :::.::.:..::::..: ::
CCDS55 AAIESPAVAAPAYSRALSRQ-LSSGVSEIRHTADRWRVSLDVNHFAPDELTVKTKDGVVE
70 80 90 100 110
100 110 120 130 140 150
pF1KE2 IHGKHNERQDDHGYISREFHRRYRLPSNVDQSALSCSLSADGMLTFCGPKIQTGLDATHA
: :::.::::.:::::: : :.: :: .:: . .: ::: .: :: .: . : .
CCDS55 ITGKHEERQDEHGYISRCFTRKYTLPPGVDPTQVSSSLSPEGTLTVEAPMPK--LATQSN
120 130 140 150 160 170
160 170
pF1KE2 ERAIPVSREEKPTSAPSS
: .:::. : .
CCDS55 EITIPVTFESRAQLGGPEAAKSDETAAK
180 190 200
>>CCDS8352.1 HSPB2 gene_id:3316|Hs108|chr11 (182 aa)
initn: 336 init1: 279 opt: 324 Z-score: 437.0 bits: 87.4 E(32554): 5.1e-18
Smith-Waterman score: 324; 38.0% identity (62.0% similar) in 158 aa overlap (19-170:21-178)
10 20 30 40 50
pF1KE2 MDVTIQHPWFKRTLGPFYPSRLFDQFFGEGLFEYDLL-PFLSSTISPYYRQSLFRTVL
:::: .: :::::. ..: : : : .
CCDS83 MSGRSVPHAHPATAEYEFANPSRLGEQRFGEGLLPEEILTPTLYHGYYVRPRAAPAGEGS
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE2 DSGISEVRSDRDKFVIFLDVKHFSPEDLTVKVQDDFVEIHGKHNERQDDHGYISREFHRR
.: ::.: .. :: ::::.::.:...::.. :...:. ..: .: : ::..:::: :
CCDS83 RAGASELRLSEGKFQAFLDVSHFTPDEVTVRTVDNLLEVSARHPQRLDRHGFVSREFCRT
70 80 90 100 110 120
120 130 140 150 160 170
pF1KE2 YRLPSNVDQSALSCSLSADGMLTFCGPKIQTGLDATHAERAI-----PVSREEKPTSAPS
: ::..:: . .:: ::.:.. .:. ::. : : : . ::. .:
CCDS83 YVLPADVDPWRVRAALSHDGILNLEAPRGGRHLDTEVNEVYISLLPAPPDPEEEEEAAIV
130 140 150 160 170 180
pF1KE2 S
CCDS83 EP
173 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 12:58:05 2016 done: Sun Nov 6 12:58:05 2016
Total Scan time: 1.900 Total Display time: -0.030
Function used was FASTA [36.3.4 Apr, 2011]