Result of FASTA (omim) for
pFN21AE1664
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE1664, 183 aa
1>>>pF1KE1664 183 - 183 aa - 183 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.1947+/-0.000299; mu= 13.3290+/- 0.019
mean_var=58.7631+/-11.454, 0's: 0 Z-trim(117.7): 104 B-trim: 0 in 0/52
Lambda= 0.167310
statistics sampled from 29758 (29864) to 29758 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.749), E-opt: 0.2 (0.35), width: 16
Scan time: 5.890
The best scores are: opt bits E(85289)
NP_003960 (OMIM: 603173) NEDD8-conjugating enzyme ( 183) 1241 307.2 9.7e-84
NP_003330 (OMIM: 602962) ubiquitin-conjugating enz ( 147) 327 86.5 2.1e-17
NP_003329 (OMIM: 602961) ubiquitin-conjugating enz ( 147) 320 84.8 6.7e-17
NP_871616 (OMIM: 602963) ubiquitin-conjugating enz ( 147) 318 84.3 9.3e-17
NP_003331 (OMIM: 602963) ubiquitin-conjugating enz ( 147) 318 84.3 9.3e-17
NP_871618 (OMIM: 602963) ubiquitin-conjugating enz ( 147) 318 84.3 9.3e-17
NP_871617 (OMIM: 602963) ubiquitin-conjugating enz ( 147) 318 84.3 9.3e-17
NP_871615 (OMIM: 602963) ubiquitin-conjugating enz ( 147) 318 84.3 9.3e-17
NP_871619 (OMIM: 602963) ubiquitin-conjugating enz ( 147) 318 84.3 9.3e-17
NP_871620 (OMIM: 602963) ubiquitin-conjugating enz ( 147) 318 84.3 9.3e-17
NP_871621 (OMIM: 602963) ubiquitin-conjugating enz ( 148) 318 84.3 9.4e-17
NP_871622 (OMIM: 602963) ubiquitin-conjugating enz ( 149) 308 81.9 5e-16
XP_016865309 (OMIM: 602962) PREDICTED: ubiquitin-c ( 173) 308 82.0 5.7e-16
NP_008950 (OMIM: 605574) ubiquitin-conjugating enz ( 179) 305 81.2 9.8e-16
NP_003328 (OMIM: 179095) ubiquitin-conjugating enz ( 152) 304 81.0 1e-15
NP_003327 (OMIM: 300860,312180) ubiquitin-conjugat ( 152) 303 80.7 1.2e-15
XP_005265489 (OMIM: 602163) PREDICTED: ubiquitin-c ( 201) 302 80.5 1.8e-15
NP_689866 (OMIM: 602163) ubiquitin-conjugating enz ( 201) 302 80.5 1.8e-15
XP_005246301 (OMIM: 604151) PREDICTED: ubiquitin-c ( 207) 298 79.6 3.6e-15
NP_006348 (OMIM: 604151) ubiquitin-conjugating enz ( 207) 298 79.6 3.6e-15
NP_001265484 (OMIM: 604151) ubiquitin-conjugating ( 207) 298 79.6 3.6e-15
NP_001265483 (OMIM: 604151) ubiquitin-conjugating ( 207) 298 79.6 3.6e-15
NP_872619 (OMIM: 604151) ubiquitin-conjugating enz ( 207) 298 79.6 3.6e-15
NP_862821 (OMIM: 602962) ubiquitin-conjugating enz ( 118) 294 78.5 4.3e-15
NP_001287724 (OMIM: 602963) ubiquitin-conjugating ( 118) 292 78.0 6e-15
XP_016864073 (OMIM: 602963) PREDICTED: ubiquitin-c ( 118) 292 78.0 6e-15
NP_003338 (OMIM: 603721) ubiquitin-conjugating enz ( 154) 293 78.3 6.4e-15
NP_003332 (OMIM: 602916) ubiquitin-conjugating enz ( 193) 290 77.6 1.3e-14
XP_016872098 (OMIM: 602961) PREDICTED: ubiquitin-c ( 110) 283 75.8 2.5e-14
NP_001269090 (OMIM: 300860,312180) ubiquitin-conju ( 119) 283 75.9 2.7e-14
NP_001243284 (OMIM: 603721) ubiquitin-conjugating ( 212) 285 76.4 3.2e-14
NP_001191809 (OMIM: 602961) ubiquitin-conjugating ( 109) 281 75.4 3.5e-14
NP_861517 (OMIM: 605574) ubiquitin-conjugating enz ( 140) 279 74.9 6.1e-14
XP_005265490 (OMIM: 602163) PREDICTED: ubiquitin-c ( 189) 277 74.5 1.1e-13
NP_003339 (OMIM: 603679) ubiquitin-conjugating enz ( 152) 273 73.5 1.8e-13
NP_919236 (OMIM: 601661) SUMO-conjugating enzyme U ( 158) 272 73.3 2.2e-13
NP_919235 (OMIM: 601661) SUMO-conjugating enzyme U ( 158) 272 73.3 2.2e-13
NP_003336 (OMIM: 601661) SUMO-conjugating enzyme U ( 158) 272 73.3 2.2e-13
NP_919237 (OMIM: 601661) SUMO-conjugating enzyme U ( 158) 272 73.3 2.2e-13
XP_016879129 (OMIM: 601661) PREDICTED: SUMO-conjug ( 158) 272 73.3 2.2e-13
NP_004214 (OMIM: 603890) ubiquitin/ISG15-conjugati ( 153) 270 72.8 3e-13
NP_055316 (OMIM: 610309) ubiquitin-conjugating enz ( 222) 271 73.1 3.5e-13
NP_001189405 (OMIM: 602916) ubiquitin-conjugating ( 160) 269 72.5 3.7e-13
NP_861516 (OMIM: 605574) ubiquitin-conjugating enz ( 150) 268 72.3 4.1e-13
NP_054895 (OMIM: 610538,616435) ubiquitin-conjugat ( 197) 264 71.4 1e-12
NP_001297255 (OMIM: 610538,616435) ubiquitin-conju ( 167) 256 69.4 3.3e-12
NP_001243285 (OMIM: 603721) ubiquitin-conjugating ( 122) 250 67.9 6.9e-12
XP_011520946 (OMIM: 601661) PREDICTED: SUMO-conjug ( 184) 251 68.2 8.4e-12
XP_005255597 (OMIM: 601661) PREDICTED: SUMO-conjug ( 184) 251 68.2 8.4e-12
XP_005255598 (OMIM: 601661) PREDICTED: SUMO-conjug ( 184) 251 68.2 8.4e-12
>>NP_003960 (OMIM: 603173) NEDD8-conjugating enzyme Ubc1 (183 aa)
initn: 1241 init1: 1241 opt: 1241 Z-score: 1624.4 bits: 307.2 E(85289): 9.7e-84
Smith-Waterman score: 1241; 100.0% identity (100.0% similar) in 183 aa overlap (1-183:1-183)
10 20 30 40 50 60
pF1KE1 MIKLFSLKQQKKEEESAGGTKGSSKKASAAQLRIQKDINELNLPKTCDISFSDPDDLLNF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 MIKLFSLKQQKKEEESAGGTKGSSKKASAAQLRIQKDINELNLPKTCDISFSDPDDLLNF
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 KLVICPDEGFYKSGKFVFSFKVGQGYPHDPPKVKCETMVYHPNIDLEGNVCLNILREDWK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 KLVICPDEGFYKSGKFVFSFKVGQGYPHDPPKVKCETMVYHPNIDLEGNVCLNILREDWK
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 PVLTINSIIYGLQYLFLEPNPEDPLNKEAAEVLQNNRRLFEQNVQRSMRGGYIGSTYFER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 PVLTINSIIYGLQYLFLEPNPEDPLNKEAAEVLQNNRRLFEQNVQRSMRGGYIGSTYFER
130 140 150 160 170 180
pF1KE1 CLK
:::
NP_003 CLK
>>NP_003330 (OMIM: 602962) ubiquitin-conjugating enzyme (147 aa)
initn: 293 init1: 261 opt: 327 Z-score: 433.6 bits: 86.5 E(85289): 2.1e-17
Smith-Waterman score: 327; 34.8% identity (71.9% similar) in 135 aa overlap (33-162:5-136)
10 20 30 40 50
pF1KE1 KLFSLKQQKKEEESAGGTKGSSKKASAAQLRIQKDINEL--NLPKTCDISFSDP--DDLL
::.:..:.: . : :. . : ::..
NP_003 MALKRIHKELNDLARDPPAQCS---AGPVGDDMF
10 20 30
60 70 80 90 100 110
pF1KE1 NFK-LVICPDEGFYKSGKFVFSFKVGQGYPHDPPKVKCETMVYHPNIDLEGNVCLNILRE
... .. :... :..: : .... :: :::: : .:::::. .:..::.:::
NP_003 HWQATIMGPNDSPYQGGVFFLTIHFPTDYPFKPPKVAFTTRIYHPNINSNGSICLDILRS
40 50 60 70 80 90
120 130 140 150 160 170
pF1KE1 DWKPVLTINSIIYGLQYLFLEPNPEDPLNKEAAEVLQNNRRLFEQNVQRSMRGGYIGSTY
.:.:.:::.... .. :. .:::.::: : :.. ...:. ...
NP_003 QWSPALTISKVLLSICSLLCDPNPDDPLVPEIARIYKTDREKYNRIAREWTQKYAM
100 110 120 130 140
180
pF1KE1 FERCLK
>>NP_003329 (OMIM: 602961) ubiquitin-conjugating enzyme (147 aa)
initn: 311 init1: 256 opt: 320 Z-score: 424.4 bits: 84.8 E(85289): 6.7e-17
Smith-Waterman score: 320; 31.9% identity (71.0% similar) in 138 aa overlap (33-165:5-139)
10 20 30 40 50
pF1KE1 KLFSLKQQKKEEESAGGTKGSSKKASAAQLRIQKDINEL--NLPKTCDISFSDP--DDLL
::::....: . : :. . : :::.
NP_003 MALKRIQKELSDLQRDPPAHCS---AGPVGDDLF
10 20 30
60 70 80 90 100 110
pF1KE1 NFK-LVICPDEGFYKSGKFVFSFKVGQGYPHDPPKVKCETMVYHPNIDLEGNVCLNILRE
... .. : .. :..: : .. . :: :::. : .:::::. .:..::.:::
NP_003 HWQATIMGPPDSAYQGGVFFLTVHFPTDYPFKPPKIAFTTKIYHPNINSNGSICLDILRS
40 50 60 70 80 90
120 130 140 150 160 170
pF1KE1 DWKPVLTINSIIYGLQYLFLEPNPEDPLNKEAAEVLQNNRRLFEQNVQRSMRGGYIGSTY
.:.:.::..... .. :. .:::.::: . :.. ..... ......
NP_003 QWSPALTVSKVLLSICSLLCDPNPDDPLVPDIAQIYKSDKEKYNRHAREWTQKYAM
100 110 120 130 140
180
pF1KE1 FERCLK
>>NP_871616 (OMIM: 602963) ubiquitin-conjugating enzyme (147 aa)
initn: 291 init1: 259 opt: 318 Z-score: 421.8 bits: 84.3 E(85289): 9.3e-17
Smith-Waterman score: 318; 35.4% identity (71.5% similar) in 130 aa overlap (33-157:5-131)
10 20 30 40 50
pF1KE1 KLFSLKQQKKEEESAGGTKGSSKKASAAQLRIQKDINEL--NLPKTCDISFSDP--DDLL
::.:....: . : :. . : ::..
NP_871 MALKRINKELSDLARDPPAQCS---AGPVGDDMF
10 20 30
60 70 80 90 100 110
pF1KE1 NFK-LVICPDEGFYKSGKFVFSFKVGQGYPHDPPKVKCETMVYHPNIDLEGNVCLNILRE
... .. :... :..: : .... :: :::: : .:::::. .:..::.:::
NP_871 HWQATIMGPNDSPYQGGVFFLTIHFPTDYPFKPPKVAFTTRIYHPNINSNGSICLDILRS
40 50 60 70 80 90
120 130 140 150 160 170
pF1KE1 DWKPVLTINSIIYGLQYLFLEPNPEDPLNKEAAEVLQNNRRLFEQNVQRSMRGGYIGSTY
.:.:.:::.... .. :. .:::.::: : :.. ...:
NP_871 QWSPALTISKVLLSICSLLCDPNPDDPLVPEIARIYKTDRDKYNRISREWTQKYAM
100 110 120 130 140
180
pF1KE1 FERCLK
>>NP_003331 (OMIM: 602963) ubiquitin-conjugating enzyme (147 aa)
initn: 291 init1: 259 opt: 318 Z-score: 421.8 bits: 84.3 E(85289): 9.3e-17
Smith-Waterman score: 318; 35.4% identity (71.5% similar) in 130 aa overlap (33-157:5-131)
10 20 30 40 50
pF1KE1 KLFSLKQQKKEEESAGGTKGSSKKASAAQLRIQKDINEL--NLPKTCDISFSDP--DDLL
::.:....: . : :. . : ::..
NP_003 MALKRINKELSDLARDPPAQCS---AGPVGDDMF
10 20 30
60 70 80 90 100 110
pF1KE1 NFK-LVICPDEGFYKSGKFVFSFKVGQGYPHDPPKVKCETMVYHPNIDLEGNVCLNILRE
... .. :... :..: : .... :: :::: : .:::::. .:..::.:::
NP_003 HWQATIMGPNDSPYQGGVFFLTIHFPTDYPFKPPKVAFTTRIYHPNINSNGSICLDILRS
40 50 60 70 80 90
120 130 140 150 160 170
pF1KE1 DWKPVLTINSIIYGLQYLFLEPNPEDPLNKEAAEVLQNNRRLFEQNVQRSMRGGYIGSTY
.:.:.:::.... .. :. .:::.::: : :.. ...:
NP_003 QWSPALTISKVLLSICSLLCDPNPDDPLVPEIARIYKTDRDKYNRISREWTQKYAM
100 110 120 130 140
180
pF1KE1 FERCLK
>>NP_871618 (OMIM: 602963) ubiquitin-conjugating enzyme (147 aa)
initn: 291 init1: 259 opt: 318 Z-score: 421.8 bits: 84.3 E(85289): 9.3e-17
Smith-Waterman score: 318; 35.4% identity (71.5% similar) in 130 aa overlap (33-157:5-131)
10 20 30 40 50
pF1KE1 KLFSLKQQKKEEESAGGTKGSSKKASAAQLRIQKDINEL--NLPKTCDISFSDP--DDLL
::.:....: . : :. . : ::..
NP_871 MALKRINKELSDLARDPPAQCS---AGPVGDDMF
10 20 30
60 70 80 90 100 110
pF1KE1 NFK-LVICPDEGFYKSGKFVFSFKVGQGYPHDPPKVKCETMVYHPNIDLEGNVCLNILRE
... .. :... :..: : .... :: :::: : .:::::. .:..::.:::
NP_871 HWQATIMGPNDSPYQGGVFFLTIHFPTDYPFKPPKVAFTTRIYHPNINSNGSICLDILRS
40 50 60 70 80 90
120 130 140 150 160 170
pF1KE1 DWKPVLTINSIIYGLQYLFLEPNPEDPLNKEAAEVLQNNRRLFEQNVQRSMRGGYIGSTY
.:.:.:::.... .. :. .:::.::: : :.. ...:
NP_871 QWSPALTISKVLLSICSLLCDPNPDDPLVPEIARIYKTDRDKYNRISREWTQKYAM
100 110 120 130 140
180
pF1KE1 FERCLK
>>NP_871617 (OMIM: 602963) ubiquitin-conjugating enzyme (147 aa)
initn: 291 init1: 259 opt: 318 Z-score: 421.8 bits: 84.3 E(85289): 9.3e-17
Smith-Waterman score: 318; 35.4% identity (71.5% similar) in 130 aa overlap (33-157:5-131)
10 20 30 40 50
pF1KE1 KLFSLKQQKKEEESAGGTKGSSKKASAAQLRIQKDINEL--NLPKTCDISFSDP--DDLL
::.:....: . : :. . : ::..
NP_871 MALKRINKELSDLARDPPAQCS---AGPVGDDMF
10 20 30
60 70 80 90 100 110
pF1KE1 NFK-LVICPDEGFYKSGKFVFSFKVGQGYPHDPPKVKCETMVYHPNIDLEGNVCLNILRE
... .. :... :..: : .... :: :::: : .:::::. .:..::.:::
NP_871 HWQATIMGPNDSPYQGGVFFLTIHFPTDYPFKPPKVAFTTRIYHPNINSNGSICLDILRS
40 50 60 70 80 90
120 130 140 150 160 170
pF1KE1 DWKPVLTINSIIYGLQYLFLEPNPEDPLNKEAAEVLQNNRRLFEQNVQRSMRGGYIGSTY
.:.:.:::.... .. :. .:::.::: : :.. ...:
NP_871 QWSPALTISKVLLSICSLLCDPNPDDPLVPEIARIYKTDRDKYNRISREWTQKYAM
100 110 120 130 140
180
pF1KE1 FERCLK
>>NP_871615 (OMIM: 602963) ubiquitin-conjugating enzyme (147 aa)
initn: 291 init1: 259 opt: 318 Z-score: 421.8 bits: 84.3 E(85289): 9.3e-17
Smith-Waterman score: 318; 35.4% identity (71.5% similar) in 130 aa overlap (33-157:5-131)
10 20 30 40 50
pF1KE1 KLFSLKQQKKEEESAGGTKGSSKKASAAQLRIQKDINEL--NLPKTCDISFSDP--DDLL
::.:....: . : :. . : ::..
NP_871 MALKRINKELSDLARDPPAQCS---AGPVGDDMF
10 20 30
60 70 80 90 100 110
pF1KE1 NFK-LVICPDEGFYKSGKFVFSFKVGQGYPHDPPKVKCETMVYHPNIDLEGNVCLNILRE
... .. :... :..: : .... :: :::: : .:::::. .:..::.:::
NP_871 HWQATIMGPNDSPYQGGVFFLTIHFPTDYPFKPPKVAFTTRIYHPNINSNGSICLDILRS
40 50 60 70 80 90
120 130 140 150 160 170
pF1KE1 DWKPVLTINSIIYGLQYLFLEPNPEDPLNKEAAEVLQNNRRLFEQNVQRSMRGGYIGSTY
.:.:.:::.... .. :. .:::.::: : :.. ...:
NP_871 QWSPALTISKVLLSICSLLCDPNPDDPLVPEIARIYKTDRDKYNRISREWTQKYAM
100 110 120 130 140
180
pF1KE1 FERCLK
>>NP_871619 (OMIM: 602963) ubiquitin-conjugating enzyme (147 aa)
initn: 291 init1: 259 opt: 318 Z-score: 421.8 bits: 84.3 E(85289): 9.3e-17
Smith-Waterman score: 318; 35.4% identity (71.5% similar) in 130 aa overlap (33-157:5-131)
10 20 30 40 50
pF1KE1 KLFSLKQQKKEEESAGGTKGSSKKASAAQLRIQKDINEL--NLPKTCDISFSDP--DDLL
::.:....: . : :. . : ::..
NP_871 MALKRINKELSDLARDPPAQCS---AGPVGDDMF
10 20 30
60 70 80 90 100 110
pF1KE1 NFK-LVICPDEGFYKSGKFVFSFKVGQGYPHDPPKVKCETMVYHPNIDLEGNVCLNILRE
... .. :... :..: : .... :: :::: : .:::::. .:..::.:::
NP_871 HWQATIMGPNDSPYQGGVFFLTIHFPTDYPFKPPKVAFTTRIYHPNINSNGSICLDILRS
40 50 60 70 80 90
120 130 140 150 160 170
pF1KE1 DWKPVLTINSIIYGLQYLFLEPNPEDPLNKEAAEVLQNNRRLFEQNVQRSMRGGYIGSTY
.:.:.:::.... .. :. .:::.::: : :.. ...:
NP_871 QWSPALTISKVLLSICSLLCDPNPDDPLVPEIARIYKTDRDKYNRISREWTQKYAM
100 110 120 130 140
180
pF1KE1 FERCLK
>>NP_871620 (OMIM: 602963) ubiquitin-conjugating enzyme (147 aa)
initn: 291 init1: 259 opt: 318 Z-score: 421.8 bits: 84.3 E(85289): 9.3e-17
Smith-Waterman score: 318; 35.4% identity (71.5% similar) in 130 aa overlap (33-157:5-131)
10 20 30 40 50
pF1KE1 KLFSLKQQKKEEESAGGTKGSSKKASAAQLRIQKDINEL--NLPKTCDISFSDP--DDLL
::.:....: . : :. . : ::..
NP_871 MALKRINKELSDLARDPPAQCS---AGPVGDDMF
10 20 30
60 70 80 90 100 110
pF1KE1 NFK-LVICPDEGFYKSGKFVFSFKVGQGYPHDPPKVKCETMVYHPNIDLEGNVCLNILRE
... .. :... :..: : .... :: :::: : .:::::. .:..::.:::
NP_871 HWQATIMGPNDSPYQGGVFFLTIHFPTDYPFKPPKVAFTTRIYHPNINSNGSICLDILRS
40 50 60 70 80 90
120 130 140 150 160 170
pF1KE1 DWKPVLTINSIIYGLQYLFLEPNPEDPLNKEAAEVLQNNRRLFEQNVQRSMRGGYIGSTY
.:.:.:::.... .. :. .:::.::: : :.. ...:
NP_871 QWSPALTISKVLLSICSLLCDPNPDDPLVPEIARIYKTDRDKYNRISREWTQKYAM
100 110 120 130 140
180
pF1KE1 FERCLK
183 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 13:11:51 2016 done: Sun Nov 6 13:11:52 2016
Total Scan time: 5.890 Total Display time: -0.020
Function used was FASTA [36.3.4 Apr, 2011]