Result of FASTA (omim) for
pFN21AE2480
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE2480, 1453 aa
1>>>pF1KE2480 1453 - 1453 aa - 1453 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 6.7710+/-0.00055; mu= 15.6993+/- 0.034
mean_var=95.4595+/-19.140, 0's: 0 Z-trim(108.6): 60 B-trim: 22 in 1/51
Lambda= 0.131270
statistics sampled from 16657 (16714) to 16657 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.537), E-opt: 0.2 (0.196), width: 16
Scan time: 15.990
The best scores are: opt bits E(85289)
NP_001035197 (OMIM: 604395,608089,614385) DNA mism (1453) 9549 1820.3 0
XP_006720179 (OMIM: 604395,608089,614385) PREDICTE (1453) 9549 1820.3 0
XP_005267591 (OMIM: 604395,608089,614385) PREDICTE (1275) 8338 1590.9 0
XP_011534948 (OMIM: 604395,608089,614385) PREDICTE (1396) 7967 1520.7 0
NP_055196 (OMIM: 604395,608089,614385) DNA mismatc (1429) 7959 1519.2 0
XP_016876708 (OMIM: 604395,608089,614385) PREDICTE (1429) 7959 1519.2 0
XP_005267590 (OMIM: 604395,608089,614385) PREDICTE (1394) 7590 1449.3 0
XP_005267589 (OMIM: 604395,608089,614385) PREDICTE (1418) 7590 1449.3 0
XP_011534950 (OMIM: 604395,608089,614385) PREDICTE (1157) 7584 1448.1 0
NP_001245200 (OMIM: 120436,158320,276300,609310) D ( 687) 392 86.0 1.1e-15
NP_000240 (OMIM: 120436,158320,276300,609310) DNA ( 756) 392 86.0 1.2e-15
NP_001121616 (OMIM: 120435,600258) PMS1 protein ho ( 770) 308 70.1 7.5e-11
XP_016859837 (OMIM: 120435,600258) PREDICTED: PMS1 ( 770) 308 70.1 7.5e-11
NP_001307974 (OMIM: 120435,600258) PMS1 protein ho ( 932) 308 70.1 8.9e-11
NP_001307977 (OMIM: 120435,600258) PMS1 protein ho ( 932) 308 70.1 8.9e-11
NP_000525 (OMIM: 120435,600258) PMS1 protein homol ( 932) 308 70.1 8.9e-11
NP_001307976 (OMIM: 120435,600258) PMS1 protein ho ( 932) 308 70.1 8.9e-11
XP_005265218 (OMIM: 120436,158320,276300,609310) P ( 687) 303 69.1 1.3e-10
NP_001307973 (OMIM: 120435,600258) PMS1 protein ho ( 731) 276 64.0 4.8e-09
NP_001121615 (OMIM: 120435,600258) PMS1 protein ho ( 893) 276 64.1 5.7e-09
XP_016859833 (OMIM: 120435,600258) PREDICTED: PMS1 ( 893) 276 64.1 5.7e-09
NP_000526 (OMIM: 276300,600259,614337) mismatch re ( 862) 274 63.7 7.2e-09
NP_001308943 (OMIM: 276300,600259,614337) mismatch ( 873) 274 63.7 7.3e-09
NP_001308935 (OMIM: 276300,600259,614337) mismatch ( 810) 245 58.2 3.1e-07
NP_001161089 (OMIM: 120436,158320,276300,609310) D ( 658) 225 54.4 3.5e-06
NP_001307978 (OMIM: 120435,600258) PMS1 protein ho ( 181) 216 52.5 3.6e-06
NP_001307980 (OMIM: 120435,600258) PMS1 protein ho ( 165) 214 52.1 4.3e-06
>>NP_001035197 (OMIM: 604395,608089,614385) DNA mismatch (1453 aa)
initn: 9549 init1: 9549 opt: 9549 Z-score: 9769.6 bits: 1820.3 E(85289): 0
Smith-Waterman score: 9549; 99.9% identity (99.9% similar) in 1453 aa overlap (1-1453:1-1453)
10 20 30 40 50 60
pF1KE2 MIKCLSVEVQAKLRSGLAISSLGQCVEELALNSIDAEAKCVAVRVNMETFQVQVIDNGFG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MIKCLSVEVQAKLRSGLAISSLGQCVEELALNSIDAEAKCVAVRVNMETFQVQVIDNGFG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 MGSDDVEKVGNRYFTSKCHSVQDLENPRFYGFRGEALANIADMASAVEISSKKNRTMKTF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MGSDDVEKVGNRYFTSKCHSVQDLENPRFYGFRGEALANIADMASAVEISSKKNRTMKTF
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 VKLFQSGKALKACEADVTRASAGTTVTVYNLFYQLPVRRKCMDPRLEFEKVRQRIEALSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VKLFQSGKALKACEADVTRASAGTTVTVYNLFYQLPVRRKCMDPRLEFEKVRQRIEALSL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE2 MHPSISFSLRNDVSGSMVLQLPKTKDVCSRFCQIYGLGKSQKLREISFKYKEFELSGYIS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MHPSISFSLRNDVSGSMVLQLPKTKDVCSRFCQIYGLGKSQKLREISFKYKEFELSGYIS
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE2 SEAHYNKNMQFLFVNKRLVLRTKLHKLIDFLLRKESIICKPKNGPTSRQMNSSLRHRSTP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SEAHYNKNMQFLFVNKRLVLRTKLHKLIDFLLRKESIICKPKNGPTSRQMNSSLRHRSTP
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE2 ELYGIYVINVQCQFCEYDVCMEPAKTLIEFQNWDTLLFCIQEGVKMFLKQEKLFVELSGE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ELYGIYVINVQCQFCEYDVCMEPAKTLIEFQNWDTLLFCIQEGVKMFLKQEKLFVELSGE
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE2 DIKEFSEDNGFSLFDATLQKRVTSDERSNFQEACNNILDSYEMFNLQSKAVKRKTTAENV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DIKEFSEDNGFSLFDATLQKRVTSDERSNFQEACNNILDSYEMFNLQSKAVKRKTTAENV
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE2 NTQSSRDSEATRKNTNDAFLYIYESGGPGHSKMTEPSLQNKDSSCSESKMLEQETIVASE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NTQSSRDSEATRKNTNDAFLYIYESGGPGHSKMTEPSLQNKDSSCSESKMLEQETIVASE
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE2 AGENEKHKKSFLEHSSLENPCGTSLEMFLSPFQTPCHFEESGQDLEIWKESTTVNGMAAN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AGENEKHKKSFLEHSSLENPCGTSLEMFLSPFQTPCHFEESGQDLEIWKESTTVNGMAAN
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE2 ILKNNRIQNQPKRFKDATEVGCQPLPFATTLWGVHSAQTEKEKKKESSNCGRRNVFSYGR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ILKNNRIQNQPKRFKDATEVGCQPLPFATTLWGVHSAQTEKEKKKESSNCGRRNVFSYGR
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE2 VKLCSTGFITHVVQNEKTKSTETEHSFKNYVRPGPTRAQETFGNRTRHSVETPDIKDLAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VKLCSTGFITHVVQNEKTKSTETEHSFKNYVRPGPTRAQETFGNRTRHSVETPDIKDLAS
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE2 TLSKESGQLPNKKNCRTNISYGLENEPTATYTMFSAFQEGSKKSQTDCILSDTSPSFPWY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TLSKESGQLPNKKNCRTNISYGLENEPTATYTMFSAFQEGSKKSQTDCILSDTSPSFPWY
670 680 690 700 710 720
730 740 750 760 770 780
pF1KE2 RHVSNDSRKTDKLIGFSKPIVRKKLSLSSQLGSLEKFKRQYGKVENPLDTEVEESNGVTT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RHVSNDSRKTDKLIGFSKPIVRKKLSLSSQLGSLEKFKRQYGKVENPLDTEVEESNGVTT
730 740 750 760 770 780
790 800 810 820 830 840
pF1KE2 NLSLQVEPDILLKDKNRLENSDVCKITTMEHSDSDSSCQPASHILDSEKFPFSKDEDCLE
:::::::::::::::::::::::::::::::::::::::::::::.::::::::::::::
NP_001 NLSLQVEPDILLKDKNRLENSDVCKITTMEHSDSDSSCQPASHILNSEKFPFSKDEDCLE
790 800 810 820 830 840
850 860 870 880 890 900
pF1KE2 QQMLSLRESPMTLKELSLFNRKPLDLEKSSESLASKLSRLKGSERETQTMGMMSRFNELP
::: ::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QQMPSLRESPMTLKELSLFNRKPLDLEKSSESLASKLSRLKGSERETQTMGMMSRFNELP
850 860 870 880 890 900
910 920 930 940 950 960
pF1KE2 NSDSSRKDSKLCSVLTQDFCMLFNNKHEKTENGVIPTSDSATQDNSFNKNSKTHSNSNTT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NSDSSRKDSKLCSVLTQDFCMLFNNKHEKTENGVIPTSDSATQDNSFNKNSKTHSNSNTT
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KE2 ENCVISETPLVLPYNNSKVTGKDSDVLIRASEQQIGSLDSPSGMLMNPVEDATGDQNGIC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ENCVISETPLVLPYNNSKVTGKDSDVLIRASEQQIGSLDSPSGMLMNPVEDATGDQNGIC
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KE2 FQSEESKARACSETEESNTCCSDWQRHFDVALGRMVYVNKMTGLSTFIAPTEDIQAACTK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FQSEESKARACSETEESNTCCSDWQRHFDVALGRMVYVNKMTGLSTFIAPTEDIQAACTK
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KE2 DLTTVAVDVVLENGSQYRCQPFRSDLVLPFLPRARAERTVMRQDNRDTVDDTVSSESLQS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DLTTVAVDVVLENGSQYRCQPFRSDLVLPFLPRARAERTVMRQDNRDTVDDTVSSESLQS
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KE2 LFSEWDNPVFARYPEVAVDVSSGQAESLAVKIHNILYPYRFTKGMIHSMQVLQQVDNKFI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LFSEWDNPVFARYPEVAVDVSSGQAESLAVKIHNILYPYRFTKGMIHSMQVLQQVDNKFI
1150 1160 1170 1180 1190 1200
1210 1220 1230 1240 1250 1260
pF1KE2 ACLMSTKTEENGEAGGNLLVLVDQHAAHERIRLEQLIIDSYEKQQAQGSGRKKLLSSTLI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ACLMSTKTEENGEAGGNLLVLVDQHAAHERIRLEQLIIDSYEKQQAQGSGRKKLLSSTLI
1210 1220 1230 1240 1250 1260
1270 1280 1290 1300 1310 1320
pF1KE2 PPLEITVTEEQRRLLWCYHKNLEDLGLEFVFPDTSDSLVLVGKVPLCFVEREANELRRGR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PPLEITVTEEQRRLLWCYHKNLEDLGLEFVFPDTSDSLVLVGKVPLCFVEREANELRRGR
1270 1280 1290 1300 1310 1320
1330 1340 1350 1360 1370 1380
pF1KE2 STVTKSIVEEFIREQLELLQTTGGIQGTLPLTVQKVLASQACHGAIKFNDGLSLQESCRL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 STVTKSIVEEFIREQLELLQTTGGIQGTLPLTVQKVLASQACHGAIKFNDGLSLQESCRL
1330 1340 1350 1360 1370 1380
1390 1400 1410 1420 1430 1440
pF1KE2 IEALSSCQLPFQCAHGRPSMLPLADIDHLEQEKQIKPNLTKLRKMAQAWRLFGKAECDTR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IEALSSCQLPFQCAHGRPSMLPLADIDHLEQEKQIKPNLTKLRKMAQAWRLFGKAECDTR
1390 1400 1410 1420 1430 1440
1450
pF1KE2 QSLQQSMPPCEPP
:::::::::::::
NP_001 QSLQQSMPPCEPP
1450
>>XP_006720179 (OMIM: 604395,608089,614385) PREDICTED: D (1453 aa)
initn: 9549 init1: 9549 opt: 9549 Z-score: 9769.6 bits: 1820.3 E(85289): 0
Smith-Waterman score: 9549; 99.9% identity (99.9% similar) in 1453 aa overlap (1-1453:1-1453)
10 20 30 40 50 60
pF1KE2 MIKCLSVEVQAKLRSGLAISSLGQCVEELALNSIDAEAKCVAVRVNMETFQVQVIDNGFG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 MIKCLSVEVQAKLRSGLAISSLGQCVEELALNSIDAEAKCVAVRVNMETFQVQVIDNGFG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 MGSDDVEKVGNRYFTSKCHSVQDLENPRFYGFRGEALANIADMASAVEISSKKNRTMKTF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 MGSDDVEKVGNRYFTSKCHSVQDLENPRFYGFRGEALANIADMASAVEISSKKNRTMKTF
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 VKLFQSGKALKACEADVTRASAGTTVTVYNLFYQLPVRRKCMDPRLEFEKVRQRIEALSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 VKLFQSGKALKACEADVTRASAGTTVTVYNLFYQLPVRRKCMDPRLEFEKVRQRIEALSL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE2 MHPSISFSLRNDVSGSMVLQLPKTKDVCSRFCQIYGLGKSQKLREISFKYKEFELSGYIS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 MHPSISFSLRNDVSGSMVLQLPKTKDVCSRFCQIYGLGKSQKLREISFKYKEFELSGYIS
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE2 SEAHYNKNMQFLFVNKRLVLRTKLHKLIDFLLRKESIICKPKNGPTSRQMNSSLRHRSTP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 SEAHYNKNMQFLFVNKRLVLRTKLHKLIDFLLRKESIICKPKNGPTSRQMNSSLRHRSTP
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE2 ELYGIYVINVQCQFCEYDVCMEPAKTLIEFQNWDTLLFCIQEGVKMFLKQEKLFVELSGE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 ELYGIYVINVQCQFCEYDVCMEPAKTLIEFQNWDTLLFCIQEGVKMFLKQEKLFVELSGE
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE2 DIKEFSEDNGFSLFDATLQKRVTSDERSNFQEACNNILDSYEMFNLQSKAVKRKTTAENV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 DIKEFSEDNGFSLFDATLQKRVTSDERSNFQEACNNILDSYEMFNLQSKAVKRKTTAENV
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE2 NTQSSRDSEATRKNTNDAFLYIYESGGPGHSKMTEPSLQNKDSSCSESKMLEQETIVASE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 NTQSSRDSEATRKNTNDAFLYIYESGGPGHSKMTEPSLQNKDSSCSESKMLEQETIVASE
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE2 AGENEKHKKSFLEHSSLENPCGTSLEMFLSPFQTPCHFEESGQDLEIWKESTTVNGMAAN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 AGENEKHKKSFLEHSSLENPCGTSLEMFLSPFQTPCHFEESGQDLEIWKESTTVNGMAAN
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE2 ILKNNRIQNQPKRFKDATEVGCQPLPFATTLWGVHSAQTEKEKKKESSNCGRRNVFSYGR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 ILKNNRIQNQPKRFKDATEVGCQPLPFATTLWGVHSAQTEKEKKKESSNCGRRNVFSYGR
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE2 VKLCSTGFITHVVQNEKTKSTETEHSFKNYVRPGPTRAQETFGNRTRHSVETPDIKDLAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 VKLCSTGFITHVVQNEKTKSTETEHSFKNYVRPGPTRAQETFGNRTRHSVETPDIKDLAS
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE2 TLSKESGQLPNKKNCRTNISYGLENEPTATYTMFSAFQEGSKKSQTDCILSDTSPSFPWY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 TLSKESGQLPNKKNCRTNISYGLENEPTATYTMFSAFQEGSKKSQTDCILSDTSPSFPWY
670 680 690 700 710 720
730 740 750 760 770 780
pF1KE2 RHVSNDSRKTDKLIGFSKPIVRKKLSLSSQLGSLEKFKRQYGKVENPLDTEVEESNGVTT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 RHVSNDSRKTDKLIGFSKPIVRKKLSLSSQLGSLEKFKRQYGKVENPLDTEVEESNGVTT
730 740 750 760 770 780
790 800 810 820 830 840
pF1KE2 NLSLQVEPDILLKDKNRLENSDVCKITTMEHSDSDSSCQPASHILDSEKFPFSKDEDCLE
:::::::::::::::::::::::::::::::::::::::::::::.::::::::::::::
XP_006 NLSLQVEPDILLKDKNRLENSDVCKITTMEHSDSDSSCQPASHILNSEKFPFSKDEDCLE
790 800 810 820 830 840
850 860 870 880 890 900
pF1KE2 QQMLSLRESPMTLKELSLFNRKPLDLEKSSESLASKLSRLKGSERETQTMGMMSRFNELP
::: ::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 QQMPSLRESPMTLKELSLFNRKPLDLEKSSESLASKLSRLKGSERETQTMGMMSRFNELP
850 860 870 880 890 900
910 920 930 940 950 960
pF1KE2 NSDSSRKDSKLCSVLTQDFCMLFNNKHEKTENGVIPTSDSATQDNSFNKNSKTHSNSNTT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 NSDSSRKDSKLCSVLTQDFCMLFNNKHEKTENGVIPTSDSATQDNSFNKNSKTHSNSNTT
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KE2 ENCVISETPLVLPYNNSKVTGKDSDVLIRASEQQIGSLDSPSGMLMNPVEDATGDQNGIC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 ENCVISETPLVLPYNNSKVTGKDSDVLIRASEQQIGSLDSPSGMLMNPVEDATGDQNGIC
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KE2 FQSEESKARACSETEESNTCCSDWQRHFDVALGRMVYVNKMTGLSTFIAPTEDIQAACTK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 FQSEESKARACSETEESNTCCSDWQRHFDVALGRMVYVNKMTGLSTFIAPTEDIQAACTK
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KE2 DLTTVAVDVVLENGSQYRCQPFRSDLVLPFLPRARAERTVMRQDNRDTVDDTVSSESLQS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 DLTTVAVDVVLENGSQYRCQPFRSDLVLPFLPRARAERTVMRQDNRDTVDDTVSSESLQS
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KE2 LFSEWDNPVFARYPEVAVDVSSGQAESLAVKIHNILYPYRFTKGMIHSMQVLQQVDNKFI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LFSEWDNPVFARYPEVAVDVSSGQAESLAVKIHNILYPYRFTKGMIHSMQVLQQVDNKFI
1150 1160 1170 1180 1190 1200
1210 1220 1230 1240 1250 1260
pF1KE2 ACLMSTKTEENGEAGGNLLVLVDQHAAHERIRLEQLIIDSYEKQQAQGSGRKKLLSSTLI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 ACLMSTKTEENGEAGGNLLVLVDQHAAHERIRLEQLIIDSYEKQQAQGSGRKKLLSSTLI
1210 1220 1230 1240 1250 1260
1270 1280 1290 1300 1310 1320
pF1KE2 PPLEITVTEEQRRLLWCYHKNLEDLGLEFVFPDTSDSLVLVGKVPLCFVEREANELRRGR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 PPLEITVTEEQRRLLWCYHKNLEDLGLEFVFPDTSDSLVLVGKVPLCFVEREANELRRGR
1270 1280 1290 1300 1310 1320
1330 1340 1350 1360 1370 1380
pF1KE2 STVTKSIVEEFIREQLELLQTTGGIQGTLPLTVQKVLASQACHGAIKFNDGLSLQESCRL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 STVTKSIVEEFIREQLELLQTTGGIQGTLPLTVQKVLASQACHGAIKFNDGLSLQESCRL
1330 1340 1350 1360 1370 1380
1390 1400 1410 1420 1430 1440
pF1KE2 IEALSSCQLPFQCAHGRPSMLPLADIDHLEQEKQIKPNLTKLRKMAQAWRLFGKAECDTR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 IEALSSCQLPFQCAHGRPSMLPLADIDHLEQEKQIKPNLTKLRKMAQAWRLFGKAECDTR
1390 1400 1410 1420 1430 1440
1450
pF1KE2 QSLQQSMPPCEPP
:::::::::::::
XP_006 QSLQQSMPPCEPP
1450
>>XP_005267591 (OMIM: 604395,608089,614385) PREDICTED: D (1275 aa)
initn: 8338 init1: 8338 opt: 8338 Z-score: 8531.1 bits: 1590.9 E(85289): 0
Smith-Waterman score: 8338; 99.8% identity (99.9% similar) in 1275 aa overlap (1-1275:1-1275)
10 20 30 40 50 60
pF1KE2 MIKCLSVEVQAKLRSGLAISSLGQCVEELALNSIDAEAKCVAVRVNMETFQVQVIDNGFG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MIKCLSVEVQAKLRSGLAISSLGQCVEELALNSIDAEAKCVAVRVNMETFQVQVIDNGFG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 MGSDDVEKVGNRYFTSKCHSVQDLENPRFYGFRGEALANIADMASAVEISSKKNRTMKTF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MGSDDVEKVGNRYFTSKCHSVQDLENPRFYGFRGEALANIADMASAVEISSKKNRTMKTF
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 VKLFQSGKALKACEADVTRASAGTTVTVYNLFYQLPVRRKCMDPRLEFEKVRQRIEALSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VKLFQSGKALKACEADVTRASAGTTVTVYNLFYQLPVRRKCMDPRLEFEKVRQRIEALSL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE2 MHPSISFSLRNDVSGSMVLQLPKTKDVCSRFCQIYGLGKSQKLREISFKYKEFELSGYIS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MHPSISFSLRNDVSGSMVLQLPKTKDVCSRFCQIYGLGKSQKLREISFKYKEFELSGYIS
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE2 SEAHYNKNMQFLFVNKRLVLRTKLHKLIDFLLRKESIICKPKNGPTSRQMNSSLRHRSTP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SEAHYNKNMQFLFVNKRLVLRTKLHKLIDFLLRKESIICKPKNGPTSRQMNSSLRHRSTP
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE2 ELYGIYVINVQCQFCEYDVCMEPAKTLIEFQNWDTLLFCIQEGVKMFLKQEKLFVELSGE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ELYGIYVINVQCQFCEYDVCMEPAKTLIEFQNWDTLLFCIQEGVKMFLKQEKLFVELSGE
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE2 DIKEFSEDNGFSLFDATLQKRVTSDERSNFQEACNNILDSYEMFNLQSKAVKRKTTAENV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DIKEFSEDNGFSLFDATLQKRVTSDERSNFQEACNNILDSYEMFNLQSKAVKRKTTAENV
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE2 NTQSSRDSEATRKNTNDAFLYIYESGGPGHSKMTEPSLQNKDSSCSESKMLEQETIVASE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 NTQSSRDSEATRKNTNDAFLYIYESGGPGHSKMTEPSLQNKDSSCSESKMLEQETIVASE
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE2 AGENEKHKKSFLEHSSLENPCGTSLEMFLSPFQTPCHFEESGQDLEIWKESTTVNGMAAN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 AGENEKHKKSFLEHSSLENPCGTSLEMFLSPFQTPCHFEESGQDLEIWKESTTVNGMAAN
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE2 ILKNNRIQNQPKRFKDATEVGCQPLPFATTLWGVHSAQTEKEKKKESSNCGRRNVFSYGR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ILKNNRIQNQPKRFKDATEVGCQPLPFATTLWGVHSAQTEKEKKKESSNCGRRNVFSYGR
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE2 VKLCSTGFITHVVQNEKTKSTETEHSFKNYVRPGPTRAQETFGNRTRHSVETPDIKDLAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VKLCSTGFITHVVQNEKTKSTETEHSFKNYVRPGPTRAQETFGNRTRHSVETPDIKDLAS
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE2 TLSKESGQLPNKKNCRTNISYGLENEPTATYTMFSAFQEGSKKSQTDCILSDTSPSFPWY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TLSKESGQLPNKKNCRTNISYGLENEPTATYTMFSAFQEGSKKSQTDCILSDTSPSFPWY
670 680 690 700 710 720
730 740 750 760 770 780
pF1KE2 RHVSNDSRKTDKLIGFSKPIVRKKLSLSSQLGSLEKFKRQYGKVENPLDTEVEESNGVTT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RHVSNDSRKTDKLIGFSKPIVRKKLSLSSQLGSLEKFKRQYGKVENPLDTEVEESNGVTT
730 740 750 760 770 780
790 800 810 820 830 840
pF1KE2 NLSLQVEPDILLKDKNRLENSDVCKITTMEHSDSDSSCQPASHILDSEKFPFSKDEDCLE
:::::::::::::::::::::::::::::::::::::::::::::.::::::::::::::
XP_005 NLSLQVEPDILLKDKNRLENSDVCKITTMEHSDSDSSCQPASHILNSEKFPFSKDEDCLE
790 800 810 820 830 840
850 860 870 880 890 900
pF1KE2 QQMLSLRESPMTLKELSLFNRKPLDLEKSSESLASKLSRLKGSERETQTMGMMSRFNELP
::: ::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QQMPSLRESPMTLKELSLFNRKPLDLEKSSESLASKLSRLKGSERETQTMGMMSRFNELP
850 860 870 880 890 900
910 920 930 940 950 960
pF1KE2 NSDSSRKDSKLCSVLTQDFCMLFNNKHEKTENGVIPTSDSATQDNSFNKNSKTHSNSNTT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 NSDSSRKDSKLCSVLTQDFCMLFNNKHEKTENGVIPTSDSATQDNSFNKNSKTHSNSNTT
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KE2 ENCVISETPLVLPYNNSKVTGKDSDVLIRASEQQIGSLDSPSGMLMNPVEDATGDQNGIC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ENCVISETPLVLPYNNSKVTGKDSDVLIRASEQQIGSLDSPSGMLMNPVEDATGDQNGIC
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KE2 FQSEESKARACSETEESNTCCSDWQRHFDVALGRMVYVNKMTGLSTFIAPTEDIQAACTK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 FQSEESKARACSETEESNTCCSDWQRHFDVALGRMVYVNKMTGLSTFIAPTEDIQAACTK
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KE2 DLTTVAVDVVLENGSQYRCQPFRSDLVLPFLPRARAERTVMRQDNRDTVDDTVSSESLQS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DLTTVAVDVVLENGSQYRCQPFRSDLVLPFLPRARAERTVMRQDNRDTVDDTVSSESLQS
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KE2 LFSEWDNPVFARYPEVAVDVSSGQAESLAVKIHNILYPYRFTKGMIHSMQVLQQVDNKFI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LFSEWDNPVFARYPEVAVDVSSGQAESLAVKIHNILYPYRFTKGMIHSMQVLQQVDNKFI
1150 1160 1170 1180 1190 1200
1210 1220 1230 1240 1250 1260
pF1KE2 ACLMSTKTEENGEAGGNLLVLVDQHAAHERIRLEQLIIDSYEKQQAQGSGRKKLLSSTLI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ACLMSTKTEENGEAGGNLLVLVDQHAAHERIRLEQLIIDSYEKQQAQGSGRKKLLSSTLI
1210 1220 1230 1240 1250 1260
1270 1280 1290 1300 1310 1320
pF1KE2 PPLEITVTEEQRRLLWCYHKNLEDLGLEFVFPDTSDSLVLVGKVPLCFVEREANELRRGR
:::::::::::::::
XP_005 PPLEITVTEEQRRLL
1270
>>XP_011534948 (OMIM: 604395,608089,614385) PREDICTED: D (1396 aa)
initn: 9152 init1: 7967 opt: 7967 Z-score: 8150.7 bits: 1520.7 E(85289): 0
Smith-Waterman score: 9041; 95.7% identity (95.9% similar) in 1453 aa overlap (1-1453:1-1396)
10 20 30 40 50 60
pF1KE2 MIKCLSVEVQAKLRSGLAISSLGQCVEELALNSIDAEAKCVAVRVNMETFQVQVIDNGFG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MIKCLSVEVQAKLRSGLAISSLGQCVEELALNSIDAEAKCVAVRVNMETFQVQVIDNGFG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 MGSDDVEKVGNRYFTSKCHSVQDLENPRFYGFRGEALANIADMASAVEISSKKNRTMKTF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MGSDDVEKVGNRYFTSKCHSVQDLENPRFYGFRGEALANIADMASAVEISSKKNRTMKTF
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 VKLFQSGKALKACEADVTRASAGTTVTVYNLFYQLPVRRKCMDPRLEFEKVRQRIEALSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VKLFQSGKALKACEADVTRASAGTTVTVYNLFYQLPVRRKCMDPRLEFEKVRQRIEALSL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE2 MHPSISFSLRNDVSGSMVLQLPKTKDVCSRFCQIYGLGKSQKLREISFKYKEFELSGYIS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MHPSISFSLRNDVSGSMVLQLPKTKDVCSRFCQIYGLGKSQKLREISFKYKEFELSGYIS
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE2 SEAHYNKNMQFLFVNKRLVLRTKLHKLIDFLLRKESIICKPKNGPTSRQMNSSLRHRSTP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SEAHYNKNMQFLFVNKRLVLRTKLHKLIDFLLRKESIICKPKNGPTSRQMNSSLRHRSTP
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE2 ELYGIYVINVQCQFCEYDVCMEPAKTLIEFQNWDTLLFCIQEGVKMFLKQEKLFVELSGE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ELYGIYVINVQCQFCEYDVCMEPAKTLIEFQNWDTLLFCIQEGVKMFLKQEKLFVELSGE
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE2 DIKEFSEDNGFSLFDATLQKRVTSDERSNFQEACNNILDSYEMFNLQSKAVKRKTTAENV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DIKEFSEDNGFSLFDATLQKRVTSDERSNFQEACNNILDSYEMFNLQSKAVKRKTTAENV
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE2 NTQSSRDSEATRKNTNDAFLYIYESGGPGHSKMTEPSLQNKDSSCSESKMLEQETIVASE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NTQSSRDSEATRKNTNDAFLYIYESGGPGHSKMTEPSLQNKDSSCSESKMLEQETIVASE
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE2 AGENEKHKKSFLEHSSLENPCGTSLEMFLSPFQTPCHFEESGQDLEIWKESTTVNGMAAN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AGENEKHKKSFLEHSSLENPCGTSLEMFLSPFQTPCHFEESGQDLEIWKESTTVNGMAAN
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE2 ILKNNRIQNQPKRFKDATEVGCQPLPFATTLWGVHSAQTEKEKKKESSNCGRRNVFSYGR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ILKNNRIQNQPKRFKDATEVGCQPLPFATTLWGVHSAQTEKEKKKESSNCGRRNVFSYGR
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE2 VKLCSTGFITHVVQNEKTKSTETEHSFKNYVRPGPTRAQETFGNRTRHSVETPDIKDLAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VKLCSTGFITHVVQNEKTKSTETEHSFKNYVRPGPTRAQETFGNRTRHSVETPDIKDLAS
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE2 TLSKESGQLPNKKNCRTNISYGLENEPTATYTMFSAFQEGSKKSQTDCILSDTSPSFPWY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TLSKESGQLPNKKNCRTNISYGLENEPTATYTMFSAFQEGSKKSQTDCILSDTSPSFPWY
670 680 690 700 710 720
730 740 750 760 770 780
pF1KE2 RHVSNDSRKTDKLIGFSKPIVRKKLSLSSQLGSLEKFKRQYGKVENPLDTEVEESNGVTT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RHVSNDSRKTDKLIGFSKPIVRKKLSLSSQLGSLEKFKRQYGKVENPLDTEVEESNGVTT
730 740 750 760 770 780
790 800 810 820 830 840
pF1KE2 NLSLQVEPDILLKDKNRLENSDVCKITTMEHSDSDSSCQPASHILDSEKFPFSKDEDCLE
:::::::::::::::::::::::::::::::::::::::::::::.::::::::::::::
XP_011 NLSLQVEPDILLKDKNRLENSDVCKITTMEHSDSDSSCQPASHILNSEKFPFSKDEDCLE
790 800 810 820 830 840
850 860 870 880 890 900
pF1KE2 QQMLSLRESPMTLKELSLFNRKPLDLEKSSESLASKLSRLKGSERETQTMGMMSRFNELP
::: ::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QQMPSLRESPMTLKELSLFNRKPLDLEKSSESLASKLSRLKGSERETQTMGMMSRFNELP
850 860 870 880 890 900
910 920 930 940 950 960
pF1KE2 NSDSSRKDSKLCSVLTQDFCMLFNNKHEKTENGVIPTSDSATQDNSFNKNSKTHSNSNTT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NSDSSRKDSKLCSVLTQDFCMLFNNKHEKTENGVIPTSDSATQDNSFNKNSKTHSNSNTT
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KE2 ENCVISETPLVLPYNNSKVTGKDSDVLIRASEQQIGSLDSPSGMLMNPVEDATGDQNGIC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ENCVISETPLVLPYNNSKVTGKDSDVLIRASEQQIGSLDSPSGMLMNPVEDATGDQNGIC
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KE2 FQSEESKARACSETEESNTCCSDWQRHFDVALGRMVYVNKMTGLSTFIAPTEDIQAACTK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FQSEESKARACSETEESNTCCSDWQRHFDVALGRMVYVNKMTGLSTFIAPTEDIQAACTK
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KE2 DLTTVAVDVVLENGSQYRCQPFRSDLVLPFLPRARAERTVMRQDNRDTVDDTVSSESLQS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DLTTVAVDVVLENGSQYRCQPFRSDLVLPFLPRARAERTVMRQDNRDTVDDTVSSESLQS
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KE2 LFSEWDNPVFARYPEVAVDVSSGQAESLAVKIHNILYPYRFTKGMIHSMQVLQQVDNKFI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LFSEWDNPVFARYPEVAVDVSSGQAESLAVKIHNILYPYRFTKGMIHSMQVLQQVDNKFI
1150 1160 1170 1180 1190 1200
1210 1220 1230 1240 1250 1260
pF1KE2 ACLMSTKTEENGEAGGNLLVLVDQHAAHERIRLEQLIIDSYEKQQAQGSGRKKLLSSTLI
:::::::::::::::
XP_011 ACLMSTKTEENGEAG---------------------------------------------
1210
1270 1280 1290 1300 1310 1320
pF1KE2 PPLEITVTEEQRRLLWCYHKNLEDLGLEFVFPDTSDSLVLVGKVPLCFVEREANELRRGR
:. ::::::::::::::::::::::::::::::::::::::::::::
XP_011 ------------YLFRCYHKNLEDLGLEFVFPDTSDSLVLVGKVPLCFVEREANELRRGR
1220 1230 1240 1250 1260
1330 1340 1350 1360 1370 1380
pF1KE2 STVTKSIVEEFIREQLELLQTTGGIQGTLPLTVQKVLASQACHGAIKFNDGLSLQESCRL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 STVTKSIVEEFIREQLELLQTTGGIQGTLPLTVQKVLASQACHGAIKFNDGLSLQESCRL
1270 1280 1290 1300 1310 1320
1390 1400 1410 1420 1430 1440
pF1KE2 IEALSSCQLPFQCAHGRPSMLPLADIDHLEQEKQIKPNLTKLRKMAQAWRLFGKAECDTR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IEALSSCQLPFQCAHGRPSMLPLADIDHLEQEKQIKPNLTKLRKMAQAWRLFGKAECDTR
1330 1340 1350 1360 1370 1380
1450
pF1KE2 QSLQQSMPPCEPP
:::::::::::::
XP_011 QSLQQSMPPCEPP
1390
>>NP_055196 (OMIM: 604395,608089,614385) DNA mismatch re (1429 aa)
initn: 9384 init1: 7959 opt: 7959 Z-score: 8142.4 bits: 1519.2 E(85289): 0
Smith-Waterman score: 9340; 98.2% identity (98.3% similar) in 1453 aa overlap (1-1453:1-1429)
10 20 30 40 50 60
pF1KE2 MIKCLSVEVQAKLRSGLAISSLGQCVEELALNSIDAEAKCVAVRVNMETFQVQVIDNGFG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 MIKCLSVEVQAKLRSGLAISSLGQCVEELALNSIDAEAKCVAVRVNMETFQVQVIDNGFG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 MGSDDVEKVGNRYFTSKCHSVQDLENPRFYGFRGEALANIADMASAVEISSKKNRTMKTF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 MGSDDVEKVGNRYFTSKCHSVQDLENPRFYGFRGEALANIADMASAVEISSKKNRTMKTF
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 VKLFQSGKALKACEADVTRASAGTTVTVYNLFYQLPVRRKCMDPRLEFEKVRQRIEALSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 VKLFQSGKALKACEADVTRASAGTTVTVYNLFYQLPVRRKCMDPRLEFEKVRQRIEALSL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE2 MHPSISFSLRNDVSGSMVLQLPKTKDVCSRFCQIYGLGKSQKLREISFKYKEFELSGYIS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 MHPSISFSLRNDVSGSMVLQLPKTKDVCSRFCQIYGLGKSQKLREISFKYKEFELSGYIS
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE2 SEAHYNKNMQFLFVNKRLVLRTKLHKLIDFLLRKESIICKPKNGPTSRQMNSSLRHRSTP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 SEAHYNKNMQFLFVNKRLVLRTKLHKLIDFLLRKESIICKPKNGPTSRQMNSSLRHRSTP
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE2 ELYGIYVINVQCQFCEYDVCMEPAKTLIEFQNWDTLLFCIQEGVKMFLKQEKLFVELSGE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 ELYGIYVINVQCQFCEYDVCMEPAKTLIEFQNWDTLLFCIQEGVKMFLKQEKLFVELSGE
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE2 DIKEFSEDNGFSLFDATLQKRVTSDERSNFQEACNNILDSYEMFNLQSKAVKRKTTAENV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 DIKEFSEDNGFSLFDATLQKRVTSDERSNFQEACNNILDSYEMFNLQSKAVKRKTTAENV
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE2 NTQSSRDSEATRKNTNDAFLYIYESGGPGHSKMTEPSLQNKDSSCSESKMLEQETIVASE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 NTQSSRDSEATRKNTNDAFLYIYESGGPGHSKMTEPSLQNKDSSCSESKMLEQETIVASE
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE2 AGENEKHKKSFLEHSSLENPCGTSLEMFLSPFQTPCHFEESGQDLEIWKESTTVNGMAAN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 AGENEKHKKSFLEHSSLENPCGTSLEMFLSPFQTPCHFEESGQDLEIWKESTTVNGMAAN
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE2 ILKNNRIQNQPKRFKDATEVGCQPLPFATTLWGVHSAQTEKEKKKESSNCGRRNVFSYGR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 ILKNNRIQNQPKRFKDATEVGCQPLPFATTLWGVHSAQTEKEKKKESSNCGRRNVFSYGR
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE2 VKLCSTGFITHVVQNEKTKSTETEHSFKNYVRPGPTRAQETFGNRTRHSVETPDIKDLAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 VKLCSTGFITHVVQNEKTKSTETEHSFKNYVRPGPTRAQETFGNRTRHSVETPDIKDLAS
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE2 TLSKESGQLPNKKNCRTNISYGLENEPTATYTMFSAFQEGSKKSQTDCILSDTSPSFPWY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 TLSKESGQLPNKKNCRTNISYGLENEPTATYTMFSAFQEGSKKSQTDCILSDTSPSFPWY
670 680 690 700 710 720
730 740 750 760 770 780
pF1KE2 RHVSNDSRKTDKLIGFSKPIVRKKLSLSSQLGSLEKFKRQYGKVENPLDTEVEESNGVTT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 RHVSNDSRKTDKLIGFSKPIVRKKLSLSSQLGSLEKFKRQYGKVENPLDTEVEESNGVTT
730 740 750 760 770 780
790 800 810 820 830 840
pF1KE2 NLSLQVEPDILLKDKNRLENSDVCKITTMEHSDSDSSCQPASHILDSEKFPFSKDEDCLE
:::::::::::::::::::::::::::::::::::::::::::::.::::::::::::::
NP_055 NLSLQVEPDILLKDKNRLENSDVCKITTMEHSDSDSSCQPASHILNSEKFPFSKDEDCLE
790 800 810 820 830 840
850 860 870 880 890 900
pF1KE2 QQMLSLRESPMTLKELSLFNRKPLDLEKSSESLASKLSRLKGSERETQTMGMMSRFNELP
::: ::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 QQMPSLRESPMTLKELSLFNRKPLDLEKSSESLASKLSRLKGSERETQTMGMMSRFNELP
850 860 870 880 890 900
910 920 930 940 950 960
pF1KE2 NSDSSRKDSKLCSVLTQDFCMLFNNKHEKTENGVIPTSDSATQDNSFNKNSKTHSNSNTT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 NSDSSRKDSKLCSVLTQDFCMLFNNKHEKTENGVIPTSDSATQDNSFNKNSKTHSNSNTT
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KE2 ENCVISETPLVLPYNNSKVTGKDSDVLIRASEQQIGSLDSPSGMLMNPVEDATGDQNGIC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 ENCVISETPLVLPYNNSKVTGKDSDVLIRASEQQIGSLDSPSGMLMNPVEDATGDQNGIC
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KE2 FQSEESKARACSETEESNTCCSDWQRHFDVALGRMVYVNKMTGLSTFIAPTEDIQAACTK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 FQSEESKARACSETEESNTCCSDWQRHFDVALGRMVYVNKMTGLSTFIAPTEDIQAACTK
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KE2 DLTTVAVDVVLENGSQYRCQPFRSDLVLPFLPRARAERTVMRQDNRDTVDDTVSSESLQS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 DLTTVAVDVVLENGSQYRCQPFRSDLVLPFLPRARAERTVMRQDNRDTVDDTVSSESLQS
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KE2 LFSEWDNPVFARYPEVAVDVSSGQAESLAVKIHNILYPYRFTKGMIHSMQVLQQVDNKFI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 LFSEWDNPVFARYPEVAVDVSSGQAESLAVKIHNILYPYRFTKGMIHSMQVLQQVDNKFI
1150 1160 1170 1180 1190 1200
1210 1220 1230 1240 1250 1260
pF1KE2 ACLMSTKTEENGEAGGNLLVLVDQHAAHERIRLEQLIIDSYEKQQAQGSGRKKLLSSTLI
:::::::::::::: ::::::::::::::::::::::
NP_055 ACLMSTKTEENGEA------------------------DSYEKQQAQGSGRKKLLSSTLI
1210 1220 1230
1270 1280 1290 1300 1310 1320
pF1KE2 PPLEITVTEEQRRLLWCYHKNLEDLGLEFVFPDTSDSLVLVGKVPLCFVEREANELRRGR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 PPLEITVTEEQRRLLWCYHKNLEDLGLEFVFPDTSDSLVLVGKVPLCFVEREANELRRGR
1240 1250 1260 1270 1280 1290
1330 1340 1350 1360 1370 1380
pF1KE2 STVTKSIVEEFIREQLELLQTTGGIQGTLPLTVQKVLASQACHGAIKFNDGLSLQESCRL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 STVTKSIVEEFIREQLELLQTTGGIQGTLPLTVQKVLASQACHGAIKFNDGLSLQESCRL
1300 1310 1320 1330 1340 1350
1390 1400 1410 1420 1430 1440
pF1KE2 IEALSSCQLPFQCAHGRPSMLPLADIDHLEQEKQIKPNLTKLRKMAQAWRLFGKAECDTR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 IEALSSCQLPFQCAHGRPSMLPLADIDHLEQEKQIKPNLTKLRKMAQAWRLFGKAECDTR
1360 1370 1380 1390 1400 1410
1450
pF1KE2 QSLQQSMPPCEPP
:::::::::::::
NP_055 QSLQQSMPPCEPP
1420
>>XP_016876708 (OMIM: 604395,608089,614385) PREDICTED: D (1429 aa)
initn: 9384 init1: 7959 opt: 7959 Z-score: 8142.4 bits: 1519.2 E(85289): 0
Smith-Waterman score: 9340; 98.2% identity (98.3% similar) in 1453 aa overlap (1-1453:1-1429)
10 20 30 40 50 60
pF1KE2 MIKCLSVEVQAKLRSGLAISSLGQCVEELALNSIDAEAKCVAVRVNMETFQVQVIDNGFG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MIKCLSVEVQAKLRSGLAISSLGQCVEELALNSIDAEAKCVAVRVNMETFQVQVIDNGFG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 MGSDDVEKVGNRYFTSKCHSVQDLENPRFYGFRGEALANIADMASAVEISSKKNRTMKTF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MGSDDVEKVGNRYFTSKCHSVQDLENPRFYGFRGEALANIADMASAVEISSKKNRTMKTF
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 VKLFQSGKALKACEADVTRASAGTTVTVYNLFYQLPVRRKCMDPRLEFEKVRQRIEALSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VKLFQSGKALKACEADVTRASAGTTVTVYNLFYQLPVRRKCMDPRLEFEKVRQRIEALSL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE2 MHPSISFSLRNDVSGSMVLQLPKTKDVCSRFCQIYGLGKSQKLREISFKYKEFELSGYIS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MHPSISFSLRNDVSGSMVLQLPKTKDVCSRFCQIYGLGKSQKLREISFKYKEFELSGYIS
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE2 SEAHYNKNMQFLFVNKRLVLRTKLHKLIDFLLRKESIICKPKNGPTSRQMNSSLRHRSTP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SEAHYNKNMQFLFVNKRLVLRTKLHKLIDFLLRKESIICKPKNGPTSRQMNSSLRHRSTP
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE2 ELYGIYVINVQCQFCEYDVCMEPAKTLIEFQNWDTLLFCIQEGVKMFLKQEKLFVELSGE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ELYGIYVINVQCQFCEYDVCMEPAKTLIEFQNWDTLLFCIQEGVKMFLKQEKLFVELSGE
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE2 DIKEFSEDNGFSLFDATLQKRVTSDERSNFQEACNNILDSYEMFNLQSKAVKRKTTAENV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DIKEFSEDNGFSLFDATLQKRVTSDERSNFQEACNNILDSYEMFNLQSKAVKRKTTAENV
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE2 NTQSSRDSEATRKNTNDAFLYIYESGGPGHSKMTEPSLQNKDSSCSESKMLEQETIVASE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NTQSSRDSEATRKNTNDAFLYIYESGGPGHSKMTEPSLQNKDSSCSESKMLEQETIVASE
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE2 AGENEKHKKSFLEHSSLENPCGTSLEMFLSPFQTPCHFEESGQDLEIWKESTTVNGMAAN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AGENEKHKKSFLEHSSLENPCGTSLEMFLSPFQTPCHFEESGQDLEIWKESTTVNGMAAN
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE2 ILKNNRIQNQPKRFKDATEVGCQPLPFATTLWGVHSAQTEKEKKKESSNCGRRNVFSYGR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ILKNNRIQNQPKRFKDATEVGCQPLPFATTLWGVHSAQTEKEKKKESSNCGRRNVFSYGR
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE2 VKLCSTGFITHVVQNEKTKSTETEHSFKNYVRPGPTRAQETFGNRTRHSVETPDIKDLAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VKLCSTGFITHVVQNEKTKSTETEHSFKNYVRPGPTRAQETFGNRTRHSVETPDIKDLAS
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE2 TLSKESGQLPNKKNCRTNISYGLENEPTATYTMFSAFQEGSKKSQTDCILSDTSPSFPWY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TLSKESGQLPNKKNCRTNISYGLENEPTATYTMFSAFQEGSKKSQTDCILSDTSPSFPWY
670 680 690 700 710 720
730 740 750 760 770 780
pF1KE2 RHVSNDSRKTDKLIGFSKPIVRKKLSLSSQLGSLEKFKRQYGKVENPLDTEVEESNGVTT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RHVSNDSRKTDKLIGFSKPIVRKKLSLSSQLGSLEKFKRQYGKVENPLDTEVEESNGVTT
730 740 750 760 770 780
790 800 810 820 830 840
pF1KE2 NLSLQVEPDILLKDKNRLENSDVCKITTMEHSDSDSSCQPASHILDSEKFPFSKDEDCLE
:::::::::::::::::::::::::::::::::::::::::::::.::::::::::::::
XP_016 NLSLQVEPDILLKDKNRLENSDVCKITTMEHSDSDSSCQPASHILNSEKFPFSKDEDCLE
790 800 810 820 830 840
850 860 870 880 890 900
pF1KE2 QQMLSLRESPMTLKELSLFNRKPLDLEKSSESLASKLSRLKGSERETQTMGMMSRFNELP
::: ::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QQMPSLRESPMTLKELSLFNRKPLDLEKSSESLASKLSRLKGSERETQTMGMMSRFNELP
850 860 870 880 890 900
910 920 930 940 950 960
pF1KE2 NSDSSRKDSKLCSVLTQDFCMLFNNKHEKTENGVIPTSDSATQDNSFNKNSKTHSNSNTT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NSDSSRKDSKLCSVLTQDFCMLFNNKHEKTENGVIPTSDSATQDNSFNKNSKTHSNSNTT
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KE2 ENCVISETPLVLPYNNSKVTGKDSDVLIRASEQQIGSLDSPSGMLMNPVEDATGDQNGIC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ENCVISETPLVLPYNNSKVTGKDSDVLIRASEQQIGSLDSPSGMLMNPVEDATGDQNGIC
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KE2 FQSEESKARACSETEESNTCCSDWQRHFDVALGRMVYVNKMTGLSTFIAPTEDIQAACTK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FQSEESKARACSETEESNTCCSDWQRHFDVALGRMVYVNKMTGLSTFIAPTEDIQAACTK
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KE2 DLTTVAVDVVLENGSQYRCQPFRSDLVLPFLPRARAERTVMRQDNRDTVDDTVSSESLQS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DLTTVAVDVVLENGSQYRCQPFRSDLVLPFLPRARAERTVMRQDNRDTVDDTVSSESLQS
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KE2 LFSEWDNPVFARYPEVAVDVSSGQAESLAVKIHNILYPYRFTKGMIHSMQVLQQVDNKFI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LFSEWDNPVFARYPEVAVDVSSGQAESLAVKIHNILYPYRFTKGMIHSMQVLQQVDNKFI
1150 1160 1170 1180 1190 1200
1210 1220 1230 1240 1250 1260
pF1KE2 ACLMSTKTEENGEAGGNLLVLVDQHAAHERIRLEQLIIDSYEKQQAQGSGRKKLLSSTLI
:::::::::::::: ::::::::::::::::::::::
XP_016 ACLMSTKTEENGEA------------------------DSYEKQQAQGSGRKKLLSSTLI
1210 1220 1230
1270 1280 1290 1300 1310 1320
pF1KE2 PPLEITVTEEQRRLLWCYHKNLEDLGLEFVFPDTSDSLVLVGKVPLCFVEREANELRRGR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PPLEITVTEEQRRLLWCYHKNLEDLGLEFVFPDTSDSLVLVGKVPLCFVEREANELRRGR
1240 1250 1260 1270 1280 1290
1330 1340 1350 1360 1370 1380
pF1KE2 STVTKSIVEEFIREQLELLQTTGGIQGTLPLTVQKVLASQACHGAIKFNDGLSLQESCRL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 STVTKSIVEEFIREQLELLQTTGGIQGTLPLTVQKVLASQACHGAIKFNDGLSLQESCRL
1300 1310 1320 1330 1340 1350
1390 1400 1410 1420 1430 1440
pF1KE2 IEALSSCQLPFQCAHGRPSMLPLADIDHLEQEKQIKPNLTKLRKMAQAWRLFGKAECDTR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IEALSSCQLPFQCAHGRPSMLPLADIDHLEQEKQIKPNLTKLRKMAQAWRLFGKAECDTR
1360 1370 1380 1390 1400 1410
1450
pF1KE2 QSLQQSMPPCEPP
:::::::::::::
XP_016 QSLQQSMPPCEPP
1420
>>XP_005267590 (OMIM: 604395,608089,614385) PREDICTED: D (1394 aa)
initn: 9014 init1: 7589 opt: 7590 Z-score: 7764.9 bits: 1449.3 E(85289): 0
Smith-Waterman score: 9037; 95.8% identity (95.9% similar) in 1453 aa overlap (1-1453:1-1394)
10 20 30 40 50 60
pF1KE2 MIKCLSVEVQAKLRSGLAISSLGQCVEELALNSIDAEAKCVAVRVNMETFQVQVIDNGFG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MIKCLSVEVQAKLRSGLAISSLGQCVEELALNSIDAEAKCVAVRVNMETFQVQVIDNGFG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 MGSDDVEKVGNRYFTSKCHSVQDLENPRFYGFRGEALANIADMASAVEISSKKNRTMKTF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MGSDDVEKVGNRYFTSKCHSVQDLENPRFYGFRGEALANIADMASAVEISSKKNRTMKTF
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 VKLFQSGKALKACEADVTRASAGTTVTVYNLFYQLPVRRKCMDPRLEFEKVRQRIEALSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VKLFQSGKALKACEADVTRASAGTTVTVYNLFYQLPVRRKCMDPRLEFEKVRQRIEALSL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE2 MHPSISFSLRNDVSGSMVLQLPKTKDVCSRFCQIYGLGKSQKLREISFKYKEFELSGYIS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MHPSISFSLRNDVSGSMVLQLPKTKDVCSRFCQIYGLGKSQKLREISFKYKEFELSGYIS
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE2 SEAHYNKNMQFLFVNKRLVLRTKLHKLIDFLLRKESIICKPKNGPTSRQMNSSLRHRSTP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SEAHYNKNMQFLFVNKRLVLRTKLHKLIDFLLRKESIICKPKNGPTSRQMNSSLRHRSTP
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE2 ELYGIYVINVQCQFCEYDVCMEPAKTLIEFQNWDTLLFCIQEGVKMFLKQEKLFVELSGE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ELYGIYVINVQCQFCEYDVCMEPAKTLIEFQNWDTLLFCIQEGVKMFLKQEKLFVELSGE
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE2 DIKEFSEDNGFSLFDATLQKRVTSDERSNFQEACNNILDSYEMFNLQSKAVKRKTTAENV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DIKEFSEDNGFSLFDATLQKRVTSDERSNFQEACNNILDSYEMFNLQSKAVKRKTTAENV
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE2 NTQSSRDSEATRKNTNDAFLYIYESGGPGHSKMTEPSLQNKDSSCSESKMLEQETIVASE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 NTQSSRDSEATRKNTNDAFLYIYESGGPGHSKMTEPSLQNKDSSCSESKMLEQETIVASE
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE2 AGENEKHKKSFLEHSSLENPCGTSLEMFLSPFQTPCHFEESGQDLEIWKESTTVNGMAAN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 AGENEKHKKSFLEHSSLENPCGTSLEMFLSPFQTPCHFEESGQDLEIWKESTTVNGMAAN
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE2 ILKNNRIQNQPKRFKDATEVGCQPLPFATTLWGVHSAQTEKEKKKESSNCGRRNVFSYGR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ILKNNRIQNQPKRFKDATEVGCQPLPFATTLWGVHSAQTEKEKKKESSNCGRRNVFSYGR
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE2 VKLCSTGFITHVVQNEKTKSTETEHSFKNYVRPGPTRAQETFGNRTRHSVETPDIKDLAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VKLCSTGFITHVVQNEKTKSTETEHSFKNYVRPGPTRAQETFGNRTRHSVETPDIKDLAS
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE2 TLSKESGQLPNKKNCRTNISYGLENEPTATYTMFSAFQEGSKKSQTDCILSDTSPSFPWY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TLSKESGQLPNKKNCRTNISYGLENEPTATYTMFSAFQEGSKKSQTDCILSDTSPSFPWY
670 680 690 700 710 720
730 740 750 760 770 780
pF1KE2 RHVSNDSRKTDKLIGFSKPIVRKKLSLSSQLGSLEKFKRQYGKVENPLDTEVEESNGVTT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RHVSNDSRKTDKLIGFSKPIVRKKLSLSSQLGSLEKFKRQYGKVENPLDTEVEESNGVTT
730 740 750 760 770 780
790 800 810 820 830 840
pF1KE2 NLSLQVEPDILLKDKNRLENSDVCKITTMEHSDSDSSCQPASHILDSEKFPFSKDEDCLE
:::::::::::::::::::::::::::::::::::::::::::::.::::::::::::::
XP_005 NLSLQVEPDILLKDKNRLENSDVCKITTMEHSDSDSSCQPASHILNSEKFPFSKDEDCLE
790 800 810 820 830 840
850 860 870 880 890 900
pF1KE2 QQMLSLRESPMTLKELSLFNRKPLDLEKSSESLASKLSRLKGSERETQTMGMMSRFNELP
::: ::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QQMPSLRESPMTLKELSLFNRKPLDLEKSSESLASKLSRLKGSERETQTMGMMSRFNELP
850 860 870 880 890 900
910 920 930 940 950 960
pF1KE2 NSDSSRKDSKLCSVLTQDFCMLFNNKHEKTENGVIPTSDSATQDNSFNKNSKTHSNSNTT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 NSDSSRKDSKLCSVLTQDFCMLFNNKHEKTENGVIPTSDSATQDNSFNKNSKTHSNSNTT
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KE2 ENCVISETPLVLPYNNSKVTGKDSDVLIRASEQQIGSLDSPSGMLMNPVEDATGDQNGIC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ENCVISETPLVLPYNNSKVTGKDSDVLIRASEQQIGSLDSPSGMLMNPVEDATGDQNGIC
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KE2 FQSEESKARACSETEESNTCCSDWQRHFDVALGRMVYVNKMTGLSTFIAPTEDIQAACTK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 FQSEESKARACSETEESNTCCSDWQRHFDVALGRMVYVNKMTGLSTFIAPTEDIQAACTK
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KE2 DLTTVAVDVVLENGSQYRCQPFRSDLVLPFLPRARAERTVMRQDNRDTVDDTVSSESLQS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DLTTVAVDVVLENGSQYRCQPFRSDLVLPFLPRARAERTVMRQDNRDTVDDTVSSESLQS
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KE2 LFSEWDNPVFARYPEVAVDVSSGQAESLAVKIHNILYPYRFTKGMIHSMQVLQQVDNKFI
:::::::::::::::: :::::::::
XP_005 LFSEWDNPVFARYPEV-----------------------------------LQQVDNKFI
1150 1160
1210 1220 1230 1240 1250 1260
pF1KE2 ACLMSTKTEENGEAGGNLLVLVDQHAAHERIRLEQLIIDSYEKQQAQGSGRKKLLSSTLI
:::::::::::::: ::::::::::::::::::::::
XP_005 ACLMSTKTEENGEA------------------------DSYEKQQAQGSGRKKLLSSTLI
1170 1180 1190 1200
1270 1280 1290 1300 1310 1320
pF1KE2 PPLEITVTEEQRRLLWCYHKNLEDLGLEFVFPDTSDSLVLVGKVPLCFVEREANELRRGR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PPLEITVTEEQRRLLWCYHKNLEDLGLEFVFPDTSDSLVLVGKVPLCFVEREANELRRGR
1210 1220 1230 1240 1250 1260
1330 1340 1350 1360 1370 1380
pF1KE2 STVTKSIVEEFIREQLELLQTTGGIQGTLPLTVQKVLASQACHGAIKFNDGLSLQESCRL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 STVTKSIVEEFIREQLELLQTTGGIQGTLPLTVQKVLASQACHGAIKFNDGLSLQESCRL
1270 1280 1290 1300 1310 1320
1390 1400 1410 1420 1430 1440
pF1KE2 IEALSSCQLPFQCAHGRPSMLPLADIDHLEQEKQIKPNLTKLRKMAQAWRLFGKAECDTR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 IEALSSCQLPFQCAHGRPSMLPLADIDHLEQEKQIKPNLTKLRKMAQAWRLFGKAECDTR
1330 1340 1350 1360 1370 1380
1450
pF1KE2 QSLQQSMPPCEPP
:::::::::::::
XP_005 QSLQQSMPPCEPP
1390
>>XP_005267589 (OMIM: 604395,608089,614385) PREDICTED: D (1418 aa)
initn: 7590 init1: 7590 opt: 7590 Z-score: 7764.8 bits: 1449.3 E(85289): 0
Smith-Waterman score: 9246; 97.5% identity (97.5% similar) in 1453 aa overlap (1-1453:1-1418)
10 20 30 40 50 60
pF1KE2 MIKCLSVEVQAKLRSGLAISSLGQCVEELALNSIDAEAKCVAVRVNMETFQVQVIDNGFG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MIKCLSVEVQAKLRSGLAISSLGQCVEELALNSIDAEAKCVAVRVNMETFQVQVIDNGFG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 MGSDDVEKVGNRYFTSKCHSVQDLENPRFYGFRGEALANIADMASAVEISSKKNRTMKTF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MGSDDVEKVGNRYFTSKCHSVQDLENPRFYGFRGEALANIADMASAVEISSKKNRTMKTF
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 VKLFQSGKALKACEADVTRASAGTTVTVYNLFYQLPVRRKCMDPRLEFEKVRQRIEALSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VKLFQSGKALKACEADVTRASAGTTVTVYNLFYQLPVRRKCMDPRLEFEKVRQRIEALSL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE2 MHPSISFSLRNDVSGSMVLQLPKTKDVCSRFCQIYGLGKSQKLREISFKYKEFELSGYIS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MHPSISFSLRNDVSGSMVLQLPKTKDVCSRFCQIYGLGKSQKLREISFKYKEFELSGYIS
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE2 SEAHYNKNMQFLFVNKRLVLRTKLHKLIDFLLRKESIICKPKNGPTSRQMNSSLRHRSTP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SEAHYNKNMQFLFVNKRLVLRTKLHKLIDFLLRKESIICKPKNGPTSRQMNSSLRHRSTP
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE2 ELYGIYVINVQCQFCEYDVCMEPAKTLIEFQNWDTLLFCIQEGVKMFLKQEKLFVELSGE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ELYGIYVINVQCQFCEYDVCMEPAKTLIEFQNWDTLLFCIQEGVKMFLKQEKLFVELSGE
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE2 DIKEFSEDNGFSLFDATLQKRVTSDERSNFQEACNNILDSYEMFNLQSKAVKRKTTAENV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DIKEFSEDNGFSLFDATLQKRVTSDERSNFQEACNNILDSYEMFNLQSKAVKRKTTAENV
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE2 NTQSSRDSEATRKNTNDAFLYIYESGGPGHSKMTEPSLQNKDSSCSESKMLEQETIVASE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 NTQSSRDSEATRKNTNDAFLYIYESGGPGHSKMTEPSLQNKDSSCSESKMLEQETIVASE
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE2 AGENEKHKKSFLEHSSLENPCGTSLEMFLSPFQTPCHFEESGQDLEIWKESTTVNGMAAN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 AGENEKHKKSFLEHSSLENPCGTSLEMFLSPFQTPCHFEESGQDLEIWKESTTVNGMAAN
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE2 ILKNNRIQNQPKRFKDATEVGCQPLPFATTLWGVHSAQTEKEKKKESSNCGRRNVFSYGR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ILKNNRIQNQPKRFKDATEVGCQPLPFATTLWGVHSAQTEKEKKKESSNCGRRNVFSYGR
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE2 VKLCSTGFITHVVQNEKTKSTETEHSFKNYVRPGPTRAQETFGNRTRHSVETPDIKDLAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VKLCSTGFITHVVQNEKTKSTETEHSFKNYVRPGPTRAQETFGNRTRHSVETPDIKDLAS
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE2 TLSKESGQLPNKKNCRTNISYGLENEPTATYTMFSAFQEGSKKSQTDCILSDTSPSFPWY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TLSKESGQLPNKKNCRTNISYGLENEPTATYTMFSAFQEGSKKSQTDCILSDTSPSFPWY
670 680 690 700 710 720
730 740 750 760 770 780
pF1KE2 RHVSNDSRKTDKLIGFSKPIVRKKLSLSSQLGSLEKFKRQYGKVENPLDTEVEESNGVTT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RHVSNDSRKTDKLIGFSKPIVRKKLSLSSQLGSLEKFKRQYGKVENPLDTEVEESNGVTT
730 740 750 760 770 780
790 800 810 820 830 840
pF1KE2 NLSLQVEPDILLKDKNRLENSDVCKITTMEHSDSDSSCQPASHILDSEKFPFSKDEDCLE
:::::::::::::::::::::::::::::::::::::::::::::.::::::::::::::
XP_005 NLSLQVEPDILLKDKNRLENSDVCKITTMEHSDSDSSCQPASHILNSEKFPFSKDEDCLE
790 800 810 820 830 840
850 860 870 880 890 900
pF1KE2 QQMLSLRESPMTLKELSLFNRKPLDLEKSSESLASKLSRLKGSERETQTMGMMSRFNELP
::: ::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QQMPSLRESPMTLKELSLFNRKPLDLEKSSESLASKLSRLKGSERETQTMGMMSRFNELP
850 860 870 880 890 900
910 920 930 940 950 960
pF1KE2 NSDSSRKDSKLCSVLTQDFCMLFNNKHEKTENGVIPTSDSATQDNSFNKNSKTHSNSNTT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 NSDSSRKDSKLCSVLTQDFCMLFNNKHEKTENGVIPTSDSATQDNSFNKNSKTHSNSNTT
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KE2 ENCVISETPLVLPYNNSKVTGKDSDVLIRASEQQIGSLDSPSGMLMNPVEDATGDQNGIC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ENCVISETPLVLPYNNSKVTGKDSDVLIRASEQQIGSLDSPSGMLMNPVEDATGDQNGIC
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KE2 FQSEESKARACSETEESNTCCSDWQRHFDVALGRMVYVNKMTGLSTFIAPTEDIQAACTK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 FQSEESKARACSETEESNTCCSDWQRHFDVALGRMVYVNKMTGLSTFIAPTEDIQAACTK
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KE2 DLTTVAVDVVLENGSQYRCQPFRSDLVLPFLPRARAERTVMRQDNRDTVDDTVSSESLQS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DLTTVAVDVVLENGSQYRCQPFRSDLVLPFLPRARAERTVMRQDNRDTVDDTVSSESLQS
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KE2 LFSEWDNPVFARYPEVAVDVSSGQAESLAVKIHNILYPYRFTKGMIHSMQVLQQVDNKFI
:::::::::::::::: :::::::::
XP_005 LFSEWDNPVFARYPEV-----------------------------------LQQVDNKFI
1150 1160
1210 1220 1230 1240 1250 1260
pF1KE2 ACLMSTKTEENGEAGGNLLVLVDQHAAHERIRLEQLIIDSYEKQQAQGSGRKKLLSSTLI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ACLMSTKTEENGEAGGNLLVLVDQHAAHERIRLEQLIIDSYEKQQAQGSGRKKLLSSTLI
1170 1180 1190 1200 1210 1220
1270 1280 1290 1300 1310 1320
pF1KE2 PPLEITVTEEQRRLLWCYHKNLEDLGLEFVFPDTSDSLVLVGKVPLCFVEREANELRRGR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PPLEITVTEEQRRLLWCYHKNLEDLGLEFVFPDTSDSLVLVGKVPLCFVEREANELRRGR
1230 1240 1250 1260 1270 1280
1330 1340 1350 1360 1370 1380
pF1KE2 STVTKSIVEEFIREQLELLQTTGGIQGTLPLTVQKVLASQACHGAIKFNDGLSLQESCRL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 STVTKSIVEEFIREQLELLQTTGGIQGTLPLTVQKVLASQACHGAIKFNDGLSLQESCRL
1290 1300 1310 1320 1330 1340
1390 1400 1410 1420 1430 1440
pF1KE2 IEALSSCQLPFQCAHGRPSMLPLADIDHLEQEKQIKPNLTKLRKMAQAWRLFGKAECDTR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 IEALSSCQLPFQCAHGRPSMLPLADIDHLEQEKQIKPNLTKLRKMAQAWRLFGKAECDTR
1350 1360 1370 1380 1390 1400
1450
pF1KE2 QSLQQSMPPCEPP
:::::::::::::
XP_005 QSLQQSMPPCEPP
1410
>>XP_011534950 (OMIM: 604395,608089,614385) PREDICTED: D (1157 aa)
initn: 7584 init1: 7584 opt: 7584 Z-score: 7760.0 bits: 1448.1 E(85289): 0
Smith-Waterman score: 7584; 99.8% identity (99.9% similar) in 1155 aa overlap (1-1155:1-1155)
10 20 30 40 50 60
pF1KE2 MIKCLSVEVQAKLRSGLAISSLGQCVEELALNSIDAEAKCVAVRVNMETFQVQVIDNGFG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MIKCLSVEVQAKLRSGLAISSLGQCVEELALNSIDAEAKCVAVRVNMETFQVQVIDNGFG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 MGSDDVEKVGNRYFTSKCHSVQDLENPRFYGFRGEALANIADMASAVEISSKKNRTMKTF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MGSDDVEKVGNRYFTSKCHSVQDLENPRFYGFRGEALANIADMASAVEISSKKNRTMKTF
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 VKLFQSGKALKACEADVTRASAGTTVTVYNLFYQLPVRRKCMDPRLEFEKVRQRIEALSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VKLFQSGKALKACEADVTRASAGTTVTVYNLFYQLPVRRKCMDPRLEFEKVRQRIEALSL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE2 MHPSISFSLRNDVSGSMVLQLPKTKDVCSRFCQIYGLGKSQKLREISFKYKEFELSGYIS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MHPSISFSLRNDVSGSMVLQLPKTKDVCSRFCQIYGLGKSQKLREISFKYKEFELSGYIS
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE2 SEAHYNKNMQFLFVNKRLVLRTKLHKLIDFLLRKESIICKPKNGPTSRQMNSSLRHRSTP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SEAHYNKNMQFLFVNKRLVLRTKLHKLIDFLLRKESIICKPKNGPTSRQMNSSLRHRSTP
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE2 ELYGIYVINVQCQFCEYDVCMEPAKTLIEFQNWDTLLFCIQEGVKMFLKQEKLFVELSGE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ELYGIYVINVQCQFCEYDVCMEPAKTLIEFQNWDTLLFCIQEGVKMFLKQEKLFVELSGE
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE2 DIKEFSEDNGFSLFDATLQKRVTSDERSNFQEACNNILDSYEMFNLQSKAVKRKTTAENV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DIKEFSEDNGFSLFDATLQKRVTSDERSNFQEACNNILDSYEMFNLQSKAVKRKTTAENV
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE2 NTQSSRDSEATRKNTNDAFLYIYESGGPGHSKMTEPSLQNKDSSCSESKMLEQETIVASE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NTQSSRDSEATRKNTNDAFLYIYESGGPGHSKMTEPSLQNKDSSCSESKMLEQETIVASE
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE2 AGENEKHKKSFLEHSSLENPCGTSLEMFLSPFQTPCHFEESGQDLEIWKESTTVNGMAAN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AGENEKHKKSFLEHSSLENPCGTSLEMFLSPFQTPCHFEESGQDLEIWKESTTVNGMAAN
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE2 ILKNNRIQNQPKRFKDATEVGCQPLPFATTLWGVHSAQTEKEKKKESSNCGRRNVFSYGR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ILKNNRIQNQPKRFKDATEVGCQPLPFATTLWGVHSAQTEKEKKKESSNCGRRNVFSYGR
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE2 VKLCSTGFITHVVQNEKTKSTETEHSFKNYVRPGPTRAQETFGNRTRHSVETPDIKDLAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VKLCSTGFITHVVQNEKTKSTETEHSFKNYVRPGPTRAQETFGNRTRHSVETPDIKDLAS
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE2 TLSKESGQLPNKKNCRTNISYGLENEPTATYTMFSAFQEGSKKSQTDCILSDTSPSFPWY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TLSKESGQLPNKKNCRTNISYGLENEPTATYTMFSAFQEGSKKSQTDCILSDTSPSFPWY
670 680 690 700 710 720
730 740 750 760 770 780
pF1KE2 RHVSNDSRKTDKLIGFSKPIVRKKLSLSSQLGSLEKFKRQYGKVENPLDTEVEESNGVTT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RHVSNDSRKTDKLIGFSKPIVRKKLSLSSQLGSLEKFKRQYGKVENPLDTEVEESNGVTT
730 740 750 760 770 780
790 800 810 820 830 840
pF1KE2 NLSLQVEPDILLKDKNRLENSDVCKITTMEHSDSDSSCQPASHILDSEKFPFSKDEDCLE
:::::::::::::::::::::::::::::::::::::::::::::.::::::::::::::
XP_011 NLSLQVEPDILLKDKNRLENSDVCKITTMEHSDSDSSCQPASHILNSEKFPFSKDEDCLE
790 800 810 820 830 840
850 860 870 880 890 900
pF1KE2 QQMLSLRESPMTLKELSLFNRKPLDLEKSSESLASKLSRLKGSERETQTMGMMSRFNELP
::: ::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QQMPSLRESPMTLKELSLFNRKPLDLEKSSESLASKLSRLKGSERETQTMGMMSRFNELP
850 860 870 880 890 900
910 920 930 940 950 960
pF1KE2 NSDSSRKDSKLCSVLTQDFCMLFNNKHEKTENGVIPTSDSATQDNSFNKNSKTHSNSNTT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NSDSSRKDSKLCSVLTQDFCMLFNNKHEKTENGVIPTSDSATQDNSFNKNSKTHSNSNTT
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KE2 ENCVISETPLVLPYNNSKVTGKDSDVLIRASEQQIGSLDSPSGMLMNPVEDATGDQNGIC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ENCVISETPLVLPYNNSKVTGKDSDVLIRASEQQIGSLDSPSGMLMNPVEDATGDQNGIC
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KE2 FQSEESKARACSETEESNTCCSDWQRHFDVALGRMVYVNKMTGLSTFIAPTEDIQAACTK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FQSEESKARACSETEESNTCCSDWQRHFDVALGRMVYVNKMTGLSTFIAPTEDIQAACTK
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KE2 DLTTVAVDVVLENGSQYRCQPFRSDLVLPFLPRARAERTVMRQDNRDTVDDTVSSESLQS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DLTTVAVDVVLENGSQYRCQPFRSDLVLPFLPRARAERTVMRQDNRDTVDDTVSSESLQS
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KE2 LFSEWDNPVFARYPEVAVDVSSGQAESLAVKIHNILYPYRFTKGMIHSMQVLQQVDNKFI
:::::::::::::::
XP_011 LFSEWDNPVFARYPESF
1150
>>NP_001245200 (OMIM: 120436,158320,276300,609310) DNA m (687 aa)
initn: 217 init1: 161 opt: 392 Z-score: 402.6 bits: 86.0 E(85289): 1.1e-15
Smith-Waterman score: 414; 26.4% identity (57.1% similar) in 508 aa overlap (1-489:7-475)
10 20 30 40 50
pF1KE2 MIKCLSVEVQAKLRSGLAISSLGQCVEELALNSIDAEAKCVAVRVNMETFQ-VQ
.:. :. : .. .: .:. .. ..:. : .::.. . : :. .. .:
NP_001 MSFVAGVIRRLDETVVNRIAAGEVIQRPANAIKEMIENCLDAKSTSIQVIVKEGGLKLIQ
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE2 VIDNGFGMGSDDVEKVGNRYFTSKCHSVQDLENPRFYGFRGEALANIADMASAVEISSKK
. ::: :. ..:.. : .:. ::: .: .:: . :::::::::.:. .: : :..:
NP_001 IQDNGTGIRKEDLDIVCERFTTSKLQSFEDLASISTYGFRGEALASISHVAH-VTITTKT
70 80 90 100 110
120 130 140 150 160 170
pF1KE2 NRTMKTFVKLFQSGKALKACEADVTRASAGTTVTVYNLFYQLPVRRKCM-DPRLEFEKVR
.. ...:: ::: . .. :: .:: .:::.. .::: . .: :. :.
NP_001 ADGKCAYRASYSDGK-LKAPPKPCA-GNQGTQITVEDLFYNIATRRKALKNPSEEYGKIL
120 130 140 150 160 170
180 190 200 210 220 230
pF1KE2 QRIEALSLMHPSISFSLRND-VSGSMVLQLPKTKDVCSRFCQIYGLGKSQKLREISFKYK
. . :. . .::::.... . . : ::... : . . .:.: . :..: ::. . :
NP_001 EVVGRYSVHNAGISFSVKKQGETVADVRTLPNASTV-DNIRSIFGNAVSRELIEIGCEDK
180 190 200 210 220 230
240 250 260 270 280
pF1KE2 E--FELSGYISSEAHYN--KNMQFLFVNKRLVLRTKLHKLIDFLLRKESIICKPKNGPTS
:...::::. :.:. : . .::.:.::: :.:.: :. . :::
NP_001 TLAFKMNGYISN-ANYSVKKCIFLLFINHRLVESTSLRKAIETVYAAYL----PKN----
240 250 260 270 280
290 300 310 320 330 340
pF1KE2 RQMNSSLRHRSTPELYGIYVINVQCQFCEYDVCMEPAKTLIEFQNWDTLLFCIQEGV---
. : :: :. : . :: ..:.: ..: . ...: .:. .
NP_001 ----------THPFLYLSLEISPQ----NVDVNVHPTKHEVHFLHEESILERVQQHIESK
290 300 310 320 330
350 360 370 380 390
pF1KE2 -------KMFLKQEKL--FVELSGEDIKEFSEDNGFSLFDATLQKRVTSDERSNFQEACN
.:.. : : .. ::: .: . .. : .. . . . :.. .:
NP_001 LLGSNSSRMYFTQTLLPGLAGPSGEMVKSTTSLTSSSTSGSSDKVYAHQMVRTDSRE---
340 350 360 370 380 390
400 410 420 430 440 450
pF1KE2 NILDSYEMFNLQSKAVKRKTTAENVNTQSSRDSEATRKNTNDAFLYIYESGGPGHSKMTE
. ::.. :: . .. . . :... : . : .: . : .:.. .
NP_001 QKLDAF----LQPLSKPLSSQPQAIVTEDKTDISSGRARQQDEEM--LELPAPAEVAAKN
400 410 420 430 440
460 470 480 490 500 510
pF1KE2 PSLQNKDSSCSESKMLEQETIVASEAGENEKHKKSFLEHSSLENPCGTSLEMFLSPFQTP
::.. :.. . :.: :.. ..:. ..:..
NP_001 QSLEG-DTTKGTSEMSEKRGPTSSNP--RKRHREDSDVEMVEDDSRKEMTAACTPRRRII
450 460 470 480 490 500
520 530 540 550 560 570
pF1KE2 CHFEESGQDLEIWKESTTVNGMAANILKNNRIQNQPKRFKDATEVGCQPLPFATTLWGVH
NP_001 NLTSVLSLQEEINEQGHEVLREMLHNHSFVGCVNPQWALAQHQTKLYLLNTTKLSEELFY
510 520 530 540 550 560
1453 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Mon Nov 7 20:44:46 2016 done: Mon Nov 7 20:44:49 2016
Total Scan time: 15.990 Total Display time: 0.780
Function used was FASTA [36.3.4 Apr, 2011]