Result of FASTA (omim) for
pFN21AE3050
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE3050, 189 aa
1>>>pF1KE3050 189 - 189 aa - 189 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.1896+/-0.000386; mu= 13.6074+/- 0.024
mean_var=63.1553+/-12.843, 0's: 0 Z-trim(112.3): 17 B-trim: 1163 in 1/49
Lambda= 0.161387
statistics sampled from 21135 (21152) to 21135 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.633), E-opt: 0.2 (0.248), width: 16
Scan time: 4.980
The best scores are: opt bits E(85289)
NP_067091 (OMIM: 147583) interferon alpha-17 precu ( 189) 1229 294.6 6.2e-80
NP_066546 (OMIM: 147564) interferon alpha-4 precur ( 189) 1177 282.5 2.8e-76
NP_002162 (OMIM: 147577) interferon alpha-10 precu ( 189) 1176 282.3 3.2e-76
NP_066401 (OMIM: 147567) interferon alpha-7 precur ( 189) 1130 271.6 5.4e-73
NP_002166 (OMIM: 147584) interferon alpha-21 precu ( 189) 1125 270.4 1.2e-72
NP_002164 (OMIM: 147580) interferon alpha-16 precu ( 189) 1082 260.4 1.3e-69
NP_002160 (OMIM: 147565) interferon alpha-5 precur ( 189) 1058 254.8 6e-68
NP_002163 (OMIM: 147579) interferon alpha-14 precu ( 189) 1049 252.7 2.6e-67
NP_000596 (OMIM: 147562) interferon alpha-2 precur ( 188) 993 239.7 2.2e-63
NP_008831 (OMIM: 147578) interferon alpha-1/13 pre ( 190) 990 239.0 3.5e-63
NP_076918 (OMIM: 147660) interferon alpha-1/13 pre ( 189) 985 237.8 7.9e-63
NP_066282 (OMIM: 147566) interferon alpha-6 precur ( 189) 984 237.6 9.3e-63
NP_002161 (OMIM: 147568) interferon alpha-8 precur ( 189) 977 235.9 2.9e-62
NP_002168 (OMIM: 147553) interferon omega-1 precur ( 195) 708 173.3 2.1e-43
NP_795372 (OMIM: 615223) interferon epsilon precur ( 208) 360 92.3 5.5e-19
NP_002167 (OMIM: 147640) interferon beta precursor ( 187) 331 85.5 5.4e-17
NP_064509 (OMIM: 615326) interferon kappa precurso ( 207) 173 48.8 7e-06
>>NP_067091 (OMIM: 147583) interferon alpha-17 precursor (189 aa)
initn: 1229 init1: 1229 opt: 1229 Z-score: 1556.0 bits: 294.6 E(85289): 6.2e-80
Smith-Waterman score: 1229; 100.0% identity (100.0% similar) in 189 aa overlap (1-189:1-189)
10 20 30 40 50 60
pF1KE3 MALSFSLLMAVLVLSYKSICSLGCDLPQTHSLGNRRALILLAQMGRISPFSCLKDRHDFG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_067 MALSFSLLMAVLVLSYKSICSLGCDLPQTHSLGNRRALILLAQMGRISPFSCLKDRHDFG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 LPQEEFDGNQFQKTQAISVLHEMIQQTFNLFSTEDSSAAWEQSLLEKFSTELYQQLNNLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_067 LPQEEFDGNQFQKTQAISVLHEMIQQTFNLFSTEDSSAAWEQSLLEKFSTELYQQLNNLE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 ACVIQEVGMEETPLMNEDSILAVRKYFQRITLYLTEKKYSPCAWEVVRAEIMRSLSFSTN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_067 ACVIQEVGMEETPLMNEDSILAVRKYFQRITLYLTEKKYSPCAWEVVRAEIMRSLSFSTN
130 140 150 160 170 180
pF1KE3 LQKILRRKD
:::::::::
NP_067 LQKILRRKD
>>NP_066546 (OMIM: 147564) interferon alpha-4 precursor (189 aa)
initn: 1177 init1: 1177 opt: 1177 Z-score: 1490.6 bits: 282.5 E(85289): 2.8e-76
Smith-Waterman score: 1177; 95.8% identity (98.9% similar) in 189 aa overlap (1-189:1-189)
10 20 30 40 50 60
pF1KE3 MALSFSLLMAVLVLSYKSICSLGCDLPQTHSLGNRRALILLAQMGRISPFSCLKDRHDFG
:::::::::::::::::::::::::::::::::::::::::::::::: :::::::::::
NP_066 MALSFSLLMAVLVLSYKSICSLGCDLPQTHSLGNRRALILLAQMGRISHFSCLKDRHDFG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 LPQEEFDGNQFQKTQAISVLHEMIQQTFNLFSTEDSSAAWEQSLLEKFSTELYQQLNNLE
.:.:::::.::::.:::::::::::::::::::::::::::::::::::::::::::.::
NP_066 FPEEEFDGHQFQKAQAISVLHEMIQQTFNLFSTEDSSAAWEQSLLEKFSTELYQQLNDLE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 ACVIQEVGMEETPLMNEDSILAVRKYFQRITLYLTEKKYSPCAWEVVRAEIMRSLSFSTN
::::::::.:::::::::::::::::::::::::::::::::::::::::::::::::::
NP_066 ACVIQEVGVEETPLMNEDSILAVRKYFQRITLYLTEKKYSPCAWEVVRAEIMRSLSFSTN
130 140 150 160 170 180
pF1KE3 LQKILRRKD
::: :::::
NP_066 LQKRLRRKD
>>NP_002162 (OMIM: 147577) interferon alpha-10 precursor (189 aa)
initn: 1176 init1: 1176 opt: 1176 Z-score: 1489.3 bits: 282.3 E(85289): 3.2e-76
Smith-Waterman score: 1176; 95.2% identity (98.4% similar) in 189 aa overlap (1-189:1-189)
10 20 30 40 50 60
pF1KE3 MALSFSLLMAVLVLSYKSICSLGCDLPQTHSLGNRRALILLAQMGRISPFSCLKDRHDFG
:::::::::::::::::::::::::::::::::::::::::.:::::::::::::::::
NP_002 MALSFSLLMAVLVLSYKSICSLGCDLPQTHSLGNRRALILLGQMGRISPFSCLKDRHDFR
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 LPQEEFDGNQFQKTQAISVLHEMIQQTFNLFSTEDSSAAWEQSLLEKFSTELYQQLNNLE
.::::::::::::.:::::::::::::::::::::::::::::::::::::::::::.::
NP_002 IPQEEFDGNQFQKAQAISVLHEMIQQTFNLFSTEDSSAAWEQSLLEKFSTELYQQLNDLE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 ACVIQEVGMEETPLMNEDSILAVRKYFQRITLYLTEKKYSPCAWEVVRAEIMRSLSFSTN
::::::::.::::::::::::::::::::::::: :.:::::::::::::::::::::::
NP_002 ACVIQEVGVEETPLMNEDSILAVRKYFQRITLYLIERKYSPCAWEVVRAEIMRSLSFSTN
130 140 150 160 170 180
pF1KE3 LQKILRRKD
::: :::::
NP_002 LQKRLRRKD
>>NP_066401 (OMIM: 147567) interferon alpha-7 precursor (189 aa)
initn: 1130 init1: 1130 opt: 1130 Z-score: 1431.4 bits: 271.6 E(85289): 5.4e-73
Smith-Waterman score: 1130; 92.1% identity (96.8% similar) in 189 aa overlap (1-189:1-189)
10 20 30 40 50 60
pF1KE3 MALSFSLLMAVLVLSYKSICSLGCDLPQTHSLGNRRALILLAQMGRISPFSCLKDRHDFG
:: ::::::.:::::::::::::::::::::: ::::::::::::::::::::::::.:
NP_066 MARSFSLLMVVLVLSYKSICSLGCDLPQTHSLRNRRALILLAQMGRISPFSCLKDRHEFR
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 LPQEEFDGNQFQKTQAISVLHEMIQQTFNLFSTEDSSAAWEQSLLEKFSTELYQQLNNLE
.:.:::::.::::::::::::::::::::::::::::::::::::::::::::::::.::
NP_066 FPEEEFDGHQFQKTQAISVLHEMIQQTFNLFSTEDSSAAWEQSLLEKFSTELYQQLNDLE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 ACVIQEVGMEETPLMNEDSILAVRKYFQRITLYLTEKKYSPCAWEVVRAEIMRSLSFSTN
::::::::.::::::::: ::::::::::::::: :::::::::::::::::::.:::::
NP_066 ACVIQEVGVEETPLMNEDFILAVRKYFQRITLYLMEKKYSPCAWEVVRAEIMRSFSFSTN
130 140 150 160 170 180
pF1KE3 LQKILRRKD
:.: :::::
NP_066 LKKGLRRKD
>>NP_002166 (OMIM: 147584) interferon alpha-21 precursor (189 aa)
initn: 1170 init1: 1125 opt: 1125 Z-score: 1425.1 bits: 270.4 E(85289): 1.2e-72
Smith-Waterman score: 1125; 91.0% identity (97.4% similar) in 189 aa overlap (1-189:1-189)
10 20 30 40 50 60
pF1KE3 MALSFSLLMAVLVLSYKSICSLGCDLPQTHSLGNRRALILLAQMGRISPFSCLKDRHDFG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 MALSFSLLMAVLVLSYKSICSLGCDLPQTHSLGNRRALILLAQMGRISPFSCLKDRHDFG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 LPQEEFDGNQFQKTQAISVLHEMIQQTFNLFSTEDSSAAWEQSLLEKFSTELYQQLNNLE
.::::::::::::.:::::::::::::::::::.::::.::::::::::::: ::::.::
NP_002 FPQEEFDGNQFQKAQAISVLHEMIQQTFNLFSTKDSSATWEQSLLEKFSTELNQQLNDLE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 ACVIQEVGMEETPLMNEDSILAVRKYFQRITLYLTEKKYSPCAWEVVRAEIMRSLSFSTN
::::::::.::::::: ::::::.::::::::::::::::::::::::::::::.:.:
NP_002 ACVIQEVGVEETPLMNVDSILAVKKYFQRITLYLTEKKYSPCAWEVVRAEIMRSFSLSKI
130 140 150 160 170 180
pF1KE3 LQKILRRKD
.:. ::::.
NP_002 FQERLRRKE
>>NP_002164 (OMIM: 147580) interferon alpha-16 precursor (189 aa)
initn: 1082 init1: 1082 opt: 1082 Z-score: 1371.0 bits: 260.4 E(85289): 1.3e-69
Smith-Waterman score: 1082; 87.3% identity (94.7% similar) in 189 aa overlap (1-189:1-189)
10 20 30 40 50 60
pF1KE3 MALSFSLLMAVLVLSYKSICSLGCDLPQTHSLGNRRALILLAQMGRISPFSCLKDRHDFG
:::::::::::::::::::::::::::::::::::::::::::::::: :::::::.:::
NP_002 MALSFSLLMAVLVLSYKSICSLGCDLPQTHSLGNRRALILLAQMGRISHFSCLKDRYDFG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 LPQEEFDGNQFQKTQAISVLHEMIQQTFNLFSTEDSSAAWEQSLLEKFSTELYQQLNNLE
.::: ::::::::.::::..:::::::::::::.::::::...::.:: ::.::::.::
NP_002 FPQEVFDGNQFQKAQAISAFHEMIQQTFNLFSTKDSSAAWDETLLDKFYIELFQQLNDLE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 ACVIQEVGMEETPLMNEDSILAVRKYFQRITLYLTEKKYSPCAWEVVRAEIMRSLSFSTN
::: ::::.:: ::::::::::::::::::::: ::::::::::::::::::.:::::
NP_002 ACVTQEVGVEEIALMNEDSILAVRKYFQRITLYLMGKKYSPCAWEVVRAEIMRSFSFSTN
130 140 150 160 170 180
pF1KE3 LQKILRRKD
::: :::::
NP_002 LQKGLRRKD
>>NP_002160 (OMIM: 147565) interferon alpha-5 precursor (189 aa)
initn: 1073 init1: 1058 opt: 1058 Z-score: 1340.8 bits: 254.8 E(85289): 6e-68
Smith-Waterman score: 1058; 82.5% identity (96.8% similar) in 189 aa overlap (1-189:1-189)
10 20 30 40 50 60
pF1KE3 MALSFSLLMAVLVLSYKSICSLGCDLPQTHSLGNRRALILLAQMGRISPFSCLKDRHDFG
::: : ::::..::. ::::::::::::::::.:::.:...:::::::::::::::::::
NP_002 MALPFVLLMALVVLNCKSICSLGCDLPQTHSLSNRRTLMIMAQMGRISPFSCLKDRHDFG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 LPQEEFDGNQFQKTQAISVLHEMIQQTFNLFSTEDSSAAWEQSLLEKFSTELYQQLNNLE
.::::::::::::.:::::::::::::::::::.::::.:...::.:: ::::::::.::
NP_002 FPQEEFDGNQFQKAQAISVLHEMIQQTFNLFSTKDSSATWDETLLDKFYTELYQQLNDLE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 ACVIQEVGMEETPLMNEDSILAVRKYFQRITLYLTEKKYSPCAWEVVRAEIMRSLSFSTN
::..::::.:.::::: ::::.::::::::::::::::::::::::::::::::.:.:.:
NP_002 ACMMQEVGVEDTPLMNVDSILTVRKYFQRITLYLTEKKYSPCAWEVVRAEIMRSFSLSAN
130 140 150 160 170 180
pF1KE3 LQKILRRKD
::. ::::.
NP_002 LQERLRRKE
>>NP_002163 (OMIM: 147579) interferon alpha-14 precursor (189 aa)
initn: 1049 init1: 1049 opt: 1049 Z-score: 1329.5 bits: 252.7 E(85289): 2.6e-67
Smith-Waterman score: 1049; 83.1% identity (94.7% similar) in 189 aa overlap (1-189:1-189)
10 20 30 40 50 60
pF1KE3 MALSFSLLMAVLVLSYKSICSLGCDLPQTHSLGNRRALILLAQMGRISPFSCLKDRHDFG
::: :.:.::..::: :: :::::.: :::::.:::.:.:.::: ::::::::::::::
NP_002 MALPFALMMALVVLSCKSSCSLGCNLSQTHSLNNRRTLMLMAQMRRISPFSCLKDRHDFE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 LPQEEFDGNQFQKTQAISVLHEMIQQTFNLFSTEDSSAAWEQSLLEKFSTELYQQLNNLE
.::::::::::::.:::::::::.:::::::::..:::::...::::: ::.::.:.::
NP_002 FPQEEFDGNQFQKAQAISVLHEMMQQTFNLFSTKNSSAAWDETLLEKFYIELFQQMNDLE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 ACVIQEVGMEETPLMNEDSILAVRKYFQRITLYLTEKKYSPCAWEVVRAEIMRSLSFSTN
::::::::.::::::::::::::.:::::::::: :::::::::::::::::::::::::
NP_002 ACVIQEVGVEETPLMNEDSILAVKKYFQRITLYLMEKKYSPCAWEVVRAEIMRSLSFSTN
130 140 150 160 170 180
pF1KE3 LQKILRRKD
::: :::::
NP_002 LQKRLRRKD
>>NP_000596 (OMIM: 147562) interferon alpha-2 precursor (188 aa)
initn: 1006 init1: 647 opt: 993 Z-score: 1259.1 bits: 239.7 E(85289): 2.2e-63
Smith-Waterman score: 993; 80.4% identity (93.1% similar) in 189 aa overlap (1-189:1-188)
10 20 30 40 50 60
pF1KE3 MALSFSLLMAVLVLSYKSICSLGCDLPQTHSLGNRRALILLAQMGRISPFSCLKDRHDFG
:::.:.::.:.:::: :: ::.:::::::::::.::.:.::::: ::: :::::::::::
NP_000 MALTFALLVALLVLSCKSSCSVGCDLPQTHSLGSRRTLMLLAQMRRISLFSCLKDRHDFG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 LPQEEFDGNQFQKTQAISVLHEMIQQTFNLFSTEDSSAAWEQSLLEKFSTELYQQLNNLE
.::::: ::::::...: :::::::: ::::::.::::::...::.:: ::::::::.::
NP_000 FPQEEF-GNQFQKAETIPVLHEMIQQIFNLFSTKDSSAAWDETLLDKFYTELYQQLNDLE
70 80 90 100 110
130 140 150 160 170 180
pF1KE3 ACVIQEVGMEETPLMNEDSILAVRKYFQRITLYLTEKKYSPCAWEVVRAEIMRSLSFSTN
::::: ::. :::::.:::::::::::::::::: :::::::::::::::::::.:.:::
NP_000 ACVIQGVGVTETPLMKEDSILAVRKYFQRITLYLKEKKYSPCAWEVVRAEIMRSFSLSTN
120 130 140 150 160 170
pF1KE3 LQKILRRKD
::. :: :.
NP_000 LQESLRSKE
180
>>NP_008831 (OMIM: 147578) interferon alpha-1/13 precurs (190 aa)
initn: 1010 init1: 990 opt: 990 Z-score: 1255.2 bits: 239.0 E(85289): 3.5e-63
Smith-Waterman score: 990; 79.4% identity (92.1% similar) in 189 aa overlap (1-189:2-190)
10 20 30 40 50
pF1KE3 MALSFSLLMAVLVLSYKSICSLGCDLPQTHSLGNRRALILLAQMGRISPFSCLKDRHDF
:: :.::::..::: :: ::::::::.:::: :::.:.:::::.:::: ::: :::::
NP_008 MMASPFALLMALVVLSCKSSCSLGCDLPETHSLDNRRTLMLLAQMSRISPSSCLMDRHDF
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE3 GLPQEEFDGNQFQKTQAISVLHEMIQQTFNLFSTEDSSAAWEQSLLEKFSTELYQQLNNL
:.::::::::::::. :::::::.::: ::::.:.::::::...::.:: ::::::::.:
NP_008 GFPQEEFDGNQFQKAPAISVLHELIQQIFNLFTTKDSSAAWDEDLLDKFCTELYQQLNDL
70 80 90 100 110 120
120 130 140 150 160 170
pF1KE3 EACVIQEVGMEETPLMNEDSILAVRKYFQRITLYLTEKKYSPCAWEVVRAEIMRSLSFST
::::.:: . :::::: ::::::.:::.::::::::::::::::::::::::::::.::
NP_008 EACVMQEERVGETPLMNADSILAVKKYFRRITLYLTEKKYSPCAWEVVRAEIMRSLSLST
130 140 150 160 170 180
180
pF1KE3 NLQKILRRKD
:::. ::::.
NP_008 NLQERLRRKE
190
189 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 04:27:06 2016 done: Sun Nov 6 04:27:07 2016
Total Scan time: 4.980 Total Display time: -0.020
Function used was FASTA [36.3.4 Apr, 2011]