Result of FASTA (omim) for
pFN21AE2508
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE2508, 454 aa
1>>>pF1KE2508 454 - 454 aa - 454 aa
Library: /omim/omim.rfq.tfa
64369986 residues in 92320 sequences
Statistics: Expectation_n fit: rho(ln(x))= 7.5193+/-0.000374; mu= 9.7640+/- 0.024
mean_var=217.1857+/-46.625, 0's: 0 Z-trim(119.0): 140 B-trim: 942 in 1/54
Lambda= 0.087028
statistics sampled from 33786 (33941) to 33786 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.696), E-opt: 0.2 (0.368), width: 16
Scan time: 4.560
The best scores are: opt bits E(92320)
NP_852556 (OMIM: 171833,269880,615214,616005) phos ( 454) 3027 393.0 9.6e-109
XP_011541795 (OMIM: 171833,269880,615214,616005) p ( 615) 2788 363.1 1.3e-99
XP_016865075 (OMIM: 171833,269880,615214,616005) p ( 633) 2788 363.1 1.3e-99
XP_005248599 (OMIM: 171833,269880,615214,616005) p ( 724) 2788 363.2 1.4e-99
NP_852664 (OMIM: 171833,269880,615214,616005) phos ( 724) 2788 363.2 1.4e-99
XP_016865074 (OMIM: 171833,269880,615214,616005) p ( 724) 2788 363.2 1.4e-99
NP_852665 (OMIM: 171833,269880,615214,616005) phos ( 424) 2771 360.8 4.3e-99
NP_001229395 (OMIM: 171833,269880,615214,616005) p ( 361) 2379 311.5 2.6e-84
NP_001107644 (OMIM: 606076) phosphatidylinositol 3 ( 461) 2374 311.0 4.6e-84
NP_003620 (OMIM: 606076) phosphatidylinositol 3-ki ( 461) 2374 311.0 4.6e-84
NP_001290357 (OMIM: 606076) phosphatidylinositol 3 ( 478) 2374 311.0 4.7e-84
NP_001315577 (OMIM: 606076) phosphatidylinositol 3 ( 417) 2185 287.2 6e-77
NP_001315579 (OMIM: 606076) phosphatidylinositol 3 ( 417) 2185 287.2 6e-77
NP_001315580 (OMIM: 606076) phosphatidylinositol 3 ( 417) 2185 287.2 6e-77
NP_001315578 (OMIM: 606076) phosphatidylinositol 3 ( 417) 2185 287.2 6e-77
NP_005018 (OMIM: 603157,603387) phosphatidylinosit ( 728) 2187 287.8 7.3e-77
NP_001315582 (OMIM: 606076) phosphatidylinositol 3 ( 380) 2008 265.0 2.8e-70
NP_001315581 (OMIM: 606076) phosphatidylinositol 3 ( 404) 1773 235.5 2.2e-61
NP_001315583 (OMIM: 606076) phosphatidylinositol 3 ( 305) 1557 208.2 2.7e-53
NP_001290358 (OMIM: 606076) phosphatidylinositol 3 ( 402) 1388 187.1 7.8e-47
>>NP_852556 (OMIM: 171833,269880,615214,616005) phosphat (454 aa)
initn: 3027 init1: 3027 opt: 3027 Z-score: 2073.9 bits: 393.0 E(92320): 9.6e-109
Smith-Waterman score: 3027; 99.8% identity (100.0% similar) in 454 aa overlap (1-454:1-454)
10 20 30 40 50 60
pF1KE2 MYNTVWNMEDLDLEYAKTDINCGTDLMFYIEMDPPALPPKPPKPTTVANNGMNNNMSLQD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_852 MYNTVWNMEDLDLEYAKTDINCGTDLMFYIEMDPPALPPKPPKPTTVANNGMNNNMSLQD
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 AEWYWGDISREEVNEKLRDTADGTFLVRDASTKMHGDYTLTLRKGGNNKLIKIFHRDGKY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_852 AEWYWGDISREEVNEKLRDTADGTFLVRDASTKMHGDYTLTLRKGGNNKLIKIFHRDGKY
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 GFSDPLTFSSVVELINHYRNESLAQYNPKLDVKLLYPVSKYQQDQVVKEDNIEAVGKKLH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_852 GFSDPLTFSSVVELINHYRNESLAQYNPKLDVKLLYPVSKYQQDQVVKEDNIEAVGKKLH
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE2 KYNTQFQEKSREYDRLYEEYTRTSQEIQMKRTAIEAFNETIKIFEEQCQTQERYSKEYIE
.:::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_852 EYNTQFQEKSREYDRLYEEYTRTSQEIQMKRTAIEAFNETIKIFEEQCQTQERYSKEYIE
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE2 KFKREGNEKEIQRIMHNYDKLKSRISEIIDSRRRLEEDLKKQAAEYREIDKRMNSIKPDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_852 KFKREGNEKEIQRIMHNYDKLKSRISEIIDSRRRLEEDLKKQAAEYREIDKRMNSIKPDL
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE2 IQLRKTRDQYLMWLTQKGVRQKKLNEWLGNENTEDQYSLVEDDEDLPHHDEKTWNVGSSN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_852 IQLRKTRDQYLMWLTQKGVRQKKLNEWLGNENTEDQYSLVEDDEDLPHHDEKTWNVGSSN
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE2 RNKAENLLRGKRDGTFLVRESSKQGCYACSVVVDGEVKHCVINKTATGYGFAEPYNLYSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_852 RNKAENLLRGKRDGTFLVRESSKQGCYACSVVVDGEVKHCVINKTATGYGFAEPYNLYSS
370 380 390 400 410 420
430 440 450
pF1KE2 LKELVLHYQHTSLVQHNDSLNVTLAYPVYAQQRR
::::::::::::::::::::::::::::::::::
NP_852 LKELVLHYQHTSLVQHNDSLNVTLAYPVYAQQRR
430 440 450
>>XP_011541795 (OMIM: 171833,269880,615214,616005) phosp (615 aa)
initn: 2786 init1: 2786 opt: 2788 Z-score: 1910.2 bits: 363.1 E(92320): 1.3e-99
Smith-Waterman score: 2788; 99.1% identity (99.5% similar) in 425 aa overlap (31-454:191-615)
10 20 30 40 50
pF1KE2 MYNTVWNMEDLDLEYAKTDINCGTDLMFYIEMDP-PALPPKPPKPTTVANNGMNNNMSLQ
: .: :::::::::::::::::::::::::
XP_011 PMLFRFSAASSDNTENLIKVIEILISTEWNERQPAPALPPKPPKPTTVANNGMNNNMSLQ
170 180 190 200 210 220
60 70 80 90 100 110
pF1KE2 DAEWYWGDISREEVNEKLRDTADGTFLVRDASTKMHGDYTLTLRKGGNNKLIKIFHRDGK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DAEWYWGDISREEVNEKLRDTADGTFLVRDASTKMHGDYTLTLRKGGNNKLIKIFHRDGK
230 240 250 260 270 280
120 130 140 150 160 170
pF1KE2 YGFSDPLTFSSVVELINHYRNESLAQYNPKLDVKLLYPVSKYQQDQVVKEDNIEAVGKKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YGFSDPLTFSSVVELINHYRNESLAQYNPKLDVKLLYPVSKYQQDQVVKEDNIEAVGKKL
290 300 310 320 330 340
180 190 200 210 220 230
pF1KE2 HKYNTQFQEKSREYDRLYEEYTRTSQEIQMKRTAIEAFNETIKIFEEQCQTQERYSKEYI
:.::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HEYNTQFQEKSREYDRLYEEYTRTSQEIQMKRTAIEAFNETIKIFEEQCQTQERYSKEYI
350 360 370 380 390 400
240 250 260 270 280 290
pF1KE2 EKFKREGNEKEIQRIMHNYDKLKSRISEIIDSRRRLEEDLKKQAAEYREIDKRMNSIKPD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EKFKREGNEKEIQRIMHNYDKLKSRISEIIDSRRRLEEDLKKQAAEYREIDKRMNSIKPD
410 420 430 440 450 460
300 310 320 330 340 350
pF1KE2 LIQLRKTRDQYLMWLTQKGVRQKKLNEWLGNENTEDQYSLVEDDEDLPHHDEKTWNVGSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LIQLRKTRDQYLMWLTQKGVRQKKLNEWLGNENTEDQYSLVEDDEDLPHHDEKTWNVGSS
470 480 490 500 510 520
360 370 380 390 400 410
pF1KE2 NRNKAENLLRGKRDGTFLVRESSKQGCYACSVVVDGEVKHCVINKTATGYGFAEPYNLYS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NRNKAENLLRGKRDGTFLVRESSKQGCYACSVVVDGEVKHCVINKTATGYGFAEPYNLYS
530 540 550 560 570 580
420 430 440 450
pF1KE2 SLKELVLHYQHTSLVQHNDSLNVTLAYPVYAQQRR
:::::::::::::::::::::::::::::::::::
XP_011 SLKELVLHYQHTSLVQHNDSLNVTLAYPVYAQQRR
590 600 610
>>XP_016865075 (OMIM: 171833,269880,615214,616005) phosp (633 aa)
initn: 2786 init1: 2786 opt: 2788 Z-score: 1910.1 bits: 363.1 E(92320): 1.3e-99
Smith-Waterman score: 2788; 99.1% identity (99.5% similar) in 425 aa overlap (31-454:209-633)
10 20 30 40 50
pF1KE2 MYNTVWNMEDLDLEYAKTDINCGTDLMFYIEMDP-PALPPKPPKPTTVANNGMNNNMSLQ
: .: :::::::::::::::::::::::::
XP_016 PMLFRFSAASSDNTENLIKVIEILISTEWNERQPAPALPPKPPKPTTVANNGMNNNMSLQ
180 190 200 210 220 230
60 70 80 90 100 110
pF1KE2 DAEWYWGDISREEVNEKLRDTADGTFLVRDASTKMHGDYTLTLRKGGNNKLIKIFHRDGK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DAEWYWGDISREEVNEKLRDTADGTFLVRDASTKMHGDYTLTLRKGGNNKLIKIFHRDGK
240 250 260 270 280 290
120 130 140 150 160 170
pF1KE2 YGFSDPLTFSSVVELINHYRNESLAQYNPKLDVKLLYPVSKYQQDQVVKEDNIEAVGKKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YGFSDPLTFSSVVELINHYRNESLAQYNPKLDVKLLYPVSKYQQDQVVKEDNIEAVGKKL
300 310 320 330 340 350
180 190 200 210 220 230
pF1KE2 HKYNTQFQEKSREYDRLYEEYTRTSQEIQMKRTAIEAFNETIKIFEEQCQTQERYSKEYI
:.::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HEYNTQFQEKSREYDRLYEEYTRTSQEIQMKRTAIEAFNETIKIFEEQCQTQERYSKEYI
360 370 380 390 400 410
240 250 260 270 280 290
pF1KE2 EKFKREGNEKEIQRIMHNYDKLKSRISEIIDSRRRLEEDLKKQAAEYREIDKRMNSIKPD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EKFKREGNEKEIQRIMHNYDKLKSRISEIIDSRRRLEEDLKKQAAEYREIDKRMNSIKPD
420 430 440 450 460 470
300 310 320 330 340 350
pF1KE2 LIQLRKTRDQYLMWLTQKGVRQKKLNEWLGNENTEDQYSLVEDDEDLPHHDEKTWNVGSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LIQLRKTRDQYLMWLTQKGVRQKKLNEWLGNENTEDQYSLVEDDEDLPHHDEKTWNVGSS
480 490 500 510 520 530
360 370 380 390 400 410
pF1KE2 NRNKAENLLRGKRDGTFLVRESSKQGCYACSVVVDGEVKHCVINKTATGYGFAEPYNLYS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NRNKAENLLRGKRDGTFLVRESSKQGCYACSVVVDGEVKHCVINKTATGYGFAEPYNLYS
540 550 560 570 580 590
420 430 440 450
pF1KE2 SLKELVLHYQHTSLVQHNDSLNVTLAYPVYAQQRR
:::::::::::::::::::::::::::::::::::
XP_016 SLKELVLHYQHTSLVQHNDSLNVTLAYPVYAQQRR
600 610 620 630
>>XP_005248599 (OMIM: 171833,269880,615214,616005) phosp (724 aa)
initn: 2786 init1: 2786 opt: 2788 Z-score: 1909.4 bits: 363.2 E(92320): 1.4e-99
Smith-Waterman score: 2788; 99.1% identity (99.5% similar) in 425 aa overlap (31-454:300-724)
10 20 30 40 50
pF1KE2 MYNTVWNMEDLDLEYAKTDINCGTDLMFYIEMDP-PALPPKPPKPTTVANNGMNNNMSLQ
: .: :::::::::::::::::::::::::
XP_005 PMLFRFSAASSDNTENLIKVIEILISTEWNERQPAPALPPKPPKPTTVANNGMNNNMSLQ
270 280 290 300 310 320
60 70 80 90 100 110
pF1KE2 DAEWYWGDISREEVNEKLRDTADGTFLVRDASTKMHGDYTLTLRKGGNNKLIKIFHRDGK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DAEWYWGDISREEVNEKLRDTADGTFLVRDASTKMHGDYTLTLRKGGNNKLIKIFHRDGK
330 340 350 360 370 380
120 130 140 150 160 170
pF1KE2 YGFSDPLTFSSVVELINHYRNESLAQYNPKLDVKLLYPVSKYQQDQVVKEDNIEAVGKKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 YGFSDPLTFSSVVELINHYRNESLAQYNPKLDVKLLYPVSKYQQDQVVKEDNIEAVGKKL
390 400 410 420 430 440
180 190 200 210 220 230
pF1KE2 HKYNTQFQEKSREYDRLYEEYTRTSQEIQMKRTAIEAFNETIKIFEEQCQTQERYSKEYI
:.::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 HEYNTQFQEKSREYDRLYEEYTRTSQEIQMKRTAIEAFNETIKIFEEQCQTQERYSKEYI
450 460 470 480 490 500
240 250 260 270 280 290
pF1KE2 EKFKREGNEKEIQRIMHNYDKLKSRISEIIDSRRRLEEDLKKQAAEYREIDKRMNSIKPD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EKFKREGNEKEIQRIMHNYDKLKSRISEIIDSRRRLEEDLKKQAAEYREIDKRMNSIKPD
510 520 530 540 550 560
300 310 320 330 340 350
pF1KE2 LIQLRKTRDQYLMWLTQKGVRQKKLNEWLGNENTEDQYSLVEDDEDLPHHDEKTWNVGSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LIQLRKTRDQYLMWLTQKGVRQKKLNEWLGNENTEDQYSLVEDDEDLPHHDEKTWNVGSS
570 580 590 600 610 620
360 370 380 390 400 410
pF1KE2 NRNKAENLLRGKRDGTFLVRESSKQGCYACSVVVDGEVKHCVINKTATGYGFAEPYNLYS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 NRNKAENLLRGKRDGTFLVRESSKQGCYACSVVVDGEVKHCVINKTATGYGFAEPYNLYS
630 640 650 660 670 680
420 430 440 450
pF1KE2 SLKELVLHYQHTSLVQHNDSLNVTLAYPVYAQQRR
:::::::::::::::::::::::::::::::::::
XP_005 SLKELVLHYQHTSLVQHNDSLNVTLAYPVYAQQRR
690 700 710 720
>>NP_852664 (OMIM: 171833,269880,615214,616005) phosphat (724 aa)
initn: 2786 init1: 2786 opt: 2788 Z-score: 1909.4 bits: 363.2 E(92320): 1.4e-99
Smith-Waterman score: 2788; 99.1% identity (99.5% similar) in 425 aa overlap (31-454:300-724)
10 20 30 40 50
pF1KE2 MYNTVWNMEDLDLEYAKTDINCGTDLMFYIEMDP-PALPPKPPKPTTVANNGMNNNMSLQ
: .: :::::::::::::::::::::::::
NP_852 PMLFRFSAASSDNTENLIKVIEILISTEWNERQPAPALPPKPPKPTTVANNGMNNNMSLQ
270 280 290 300 310 320
60 70 80 90 100 110
pF1KE2 DAEWYWGDISREEVNEKLRDTADGTFLVRDASTKMHGDYTLTLRKGGNNKLIKIFHRDGK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_852 DAEWYWGDISREEVNEKLRDTADGTFLVRDASTKMHGDYTLTLRKGGNNKLIKIFHRDGK
330 340 350 360 370 380
120 130 140 150 160 170
pF1KE2 YGFSDPLTFSSVVELINHYRNESLAQYNPKLDVKLLYPVSKYQQDQVVKEDNIEAVGKKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_852 YGFSDPLTFSSVVELINHYRNESLAQYNPKLDVKLLYPVSKYQQDQVVKEDNIEAVGKKL
390 400 410 420 430 440
180 190 200 210 220 230
pF1KE2 HKYNTQFQEKSREYDRLYEEYTRTSQEIQMKRTAIEAFNETIKIFEEQCQTQERYSKEYI
:.::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_852 HEYNTQFQEKSREYDRLYEEYTRTSQEIQMKRTAIEAFNETIKIFEEQCQTQERYSKEYI
450 460 470 480 490 500
240 250 260 270 280 290
pF1KE2 EKFKREGNEKEIQRIMHNYDKLKSRISEIIDSRRRLEEDLKKQAAEYREIDKRMNSIKPD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_852 EKFKREGNEKEIQRIMHNYDKLKSRISEIIDSRRRLEEDLKKQAAEYREIDKRMNSIKPD
510 520 530 540 550 560
300 310 320 330 340 350
pF1KE2 LIQLRKTRDQYLMWLTQKGVRQKKLNEWLGNENTEDQYSLVEDDEDLPHHDEKTWNVGSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_852 LIQLRKTRDQYLMWLTQKGVRQKKLNEWLGNENTEDQYSLVEDDEDLPHHDEKTWNVGSS
570 580 590 600 610 620
360 370 380 390 400 410
pF1KE2 NRNKAENLLRGKRDGTFLVRESSKQGCYACSVVVDGEVKHCVINKTATGYGFAEPYNLYS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_852 NRNKAENLLRGKRDGTFLVRESSKQGCYACSVVVDGEVKHCVINKTATGYGFAEPYNLYS
630 640 650 660 670 680
420 430 440 450
pF1KE2 SLKELVLHYQHTSLVQHNDSLNVTLAYPVYAQQRR
:::::::::::::::::::::::::::::::::::
NP_852 SLKELVLHYQHTSLVQHNDSLNVTLAYPVYAQQRR
690 700 710 720
>>XP_016865074 (OMIM: 171833,269880,615214,616005) phosp (724 aa)
initn: 2786 init1: 2786 opt: 2788 Z-score: 1909.4 bits: 363.2 E(92320): 1.4e-99
Smith-Waterman score: 2788; 99.1% identity (99.5% similar) in 425 aa overlap (31-454:300-724)
10 20 30 40 50
pF1KE2 MYNTVWNMEDLDLEYAKTDINCGTDLMFYIEMDP-PALPPKPPKPTTVANNGMNNNMSLQ
: .: :::::::::::::::::::::::::
XP_016 PMLFRFSAASSDNTENLIKVIEILISTEWNERQPAPALPPKPPKPTTVANNGMNNNMSLQ
270 280 290 300 310 320
60 70 80 90 100 110
pF1KE2 DAEWYWGDISREEVNEKLRDTADGTFLVRDASTKMHGDYTLTLRKGGNNKLIKIFHRDGK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DAEWYWGDISREEVNEKLRDTADGTFLVRDASTKMHGDYTLTLRKGGNNKLIKIFHRDGK
330 340 350 360 370 380
120 130 140 150 160 170
pF1KE2 YGFSDPLTFSSVVELINHYRNESLAQYNPKLDVKLLYPVSKYQQDQVVKEDNIEAVGKKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YGFSDPLTFSSVVELINHYRNESLAQYNPKLDVKLLYPVSKYQQDQVVKEDNIEAVGKKL
390 400 410 420 430 440
180 190 200 210 220 230
pF1KE2 HKYNTQFQEKSREYDRLYEEYTRTSQEIQMKRTAIEAFNETIKIFEEQCQTQERYSKEYI
:.::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HEYNTQFQEKSREYDRLYEEYTRTSQEIQMKRTAIEAFNETIKIFEEQCQTQERYSKEYI
450 460 470 480 490 500
240 250 260 270 280 290
pF1KE2 EKFKREGNEKEIQRIMHNYDKLKSRISEIIDSRRRLEEDLKKQAAEYREIDKRMNSIKPD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EKFKREGNEKEIQRIMHNYDKLKSRISEIIDSRRRLEEDLKKQAAEYREIDKRMNSIKPD
510 520 530 540 550 560
300 310 320 330 340 350
pF1KE2 LIQLRKTRDQYLMWLTQKGVRQKKLNEWLGNENTEDQYSLVEDDEDLPHHDEKTWNVGSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LIQLRKTRDQYLMWLTQKGVRQKKLNEWLGNENTEDQYSLVEDDEDLPHHDEKTWNVGSS
570 580 590 600 610 620
360 370 380 390 400 410
pF1KE2 NRNKAENLLRGKRDGTFLVRESSKQGCYACSVVVDGEVKHCVINKTATGYGFAEPYNLYS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NRNKAENLLRGKRDGTFLVRESSKQGCYACSVVVDGEVKHCVINKTATGYGFAEPYNLYS
630 640 650 660 670 680
420 430 440 450
pF1KE2 SLKELVLHYQHTSLVQHNDSLNVTLAYPVYAQQRR
:::::::::::::::::::::::::::::::::::
XP_016 SLKELVLHYQHTSLVQHNDSLNVTLAYPVYAQQRR
690 700 710 720
>>NP_852665 (OMIM: 171833,269880,615214,616005) phosphat (424 aa)
initn: 2771 init1: 2771 opt: 2771 Z-score: 1900.6 bits: 360.8 E(92320): 4.3e-99
Smith-Waterman score: 2771; 99.8% identity (100.0% similar) in 418 aa overlap (37-454:7-424)
10 20 30 40 50 60
pF1KE2 NMEDLDLEYAKTDINCGTDLMFYIEMDPPALPPKPPKPTTVANNGMNNNMSLQDAEWYWG
::::::::::::::::::::::::::::::
NP_852 MHNLQTLPPKPPKPTTVANNGMNNNMSLQDAEWYWG
10 20 30
70 80 90 100 110 120
pF1KE2 DISREEVNEKLRDTADGTFLVRDASTKMHGDYTLTLRKGGNNKLIKIFHRDGKYGFSDPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_852 DISREEVNEKLRDTADGTFLVRDASTKMHGDYTLTLRKGGNNKLIKIFHRDGKYGFSDPL
40 50 60 70 80 90
130 140 150 160 170 180
pF1KE2 TFSSVVELINHYRNESLAQYNPKLDVKLLYPVSKYQQDQVVKEDNIEAVGKKLHKYNTQF
::::::::::::::::::::::::::::::::::::::::::::::::::::::.:::::
NP_852 TFSSVVELINHYRNESLAQYNPKLDVKLLYPVSKYQQDQVVKEDNIEAVGKKLHEYNTQF
100 110 120 130 140 150
190 200 210 220 230 240
pF1KE2 QEKSREYDRLYEEYTRTSQEIQMKRTAIEAFNETIKIFEEQCQTQERYSKEYIEKFKREG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_852 QEKSREYDRLYEEYTRTSQEIQMKRTAIEAFNETIKIFEEQCQTQERYSKEYIEKFKREG
160 170 180 190 200 210
250 260 270 280 290 300
pF1KE2 NEKEIQRIMHNYDKLKSRISEIIDSRRRLEEDLKKQAAEYREIDKRMNSIKPDLIQLRKT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_852 NEKEIQRIMHNYDKLKSRISEIIDSRRRLEEDLKKQAAEYREIDKRMNSIKPDLIQLRKT
220 230 240 250 260 270
310 320 330 340 350 360
pF1KE2 RDQYLMWLTQKGVRQKKLNEWLGNENTEDQYSLVEDDEDLPHHDEKTWNVGSSNRNKAEN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_852 RDQYLMWLTQKGVRQKKLNEWLGNENTEDQYSLVEDDEDLPHHDEKTWNVGSSNRNKAEN
280 290 300 310 320 330
370 380 390 400 410 420
pF1KE2 LLRGKRDGTFLVRESSKQGCYACSVVVDGEVKHCVINKTATGYGFAEPYNLYSSLKELVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_852 LLRGKRDGTFLVRESSKQGCYACSVVVDGEVKHCVINKTATGYGFAEPYNLYSSLKELVL
340 350 360 370 380 390
430 440 450
pF1KE2 HYQHTSLVQHNDSLNVTLAYPVYAQQRR
::::::::::::::::::::::::::::
NP_852 HYQHTSLVQHNDSLNVTLAYPVYAQQRR
400 410 420
>>NP_001229395 (OMIM: 171833,269880,615214,616005) phosp (361 aa)
initn: 2379 init1: 2379 opt: 2379 Z-score: 1635.4 bits: 311.5 E(92320): 2.6e-84
Smith-Waterman score: 2379; 99.7% identity (100.0% similar) in 361 aa overlap (94-454:1-361)
70 80 90 100 110 120
pF1KE2 YWGDISREEVNEKLRDTADGTFLVRDASTKMHGDYTLTLRKGGNNKLIKIFHRDGKYGFS
::::::::::::::::::::::::::::::
NP_001 MHGDYTLTLRKGGNNKLIKIFHRDGKYGFS
10 20 30
130 140 150 160 170 180
pF1KE2 DPLTFSSVVELINHYRNESLAQYNPKLDVKLLYPVSKYQQDQVVKEDNIEAVGKKLHKYN
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::.::
NP_001 DPLTFSSVVELINHYRNESLAQYNPKLDVKLLYPVSKYQQDQVVKEDNIEAVGKKLHEYN
40 50 60 70 80 90
190 200 210 220 230 240
pF1KE2 TQFQEKSREYDRLYEEYTRTSQEIQMKRTAIEAFNETIKIFEEQCQTQERYSKEYIEKFK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TQFQEKSREYDRLYEEYTRTSQEIQMKRTAIEAFNETIKIFEEQCQTQERYSKEYIEKFK
100 110 120 130 140 150
250 260 270 280 290 300
pF1KE2 REGNEKEIQRIMHNYDKLKSRISEIIDSRRRLEEDLKKQAAEYREIDKRMNSIKPDLIQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 REGNEKEIQRIMHNYDKLKSRISEIIDSRRRLEEDLKKQAAEYREIDKRMNSIKPDLIQL
160 170 180 190 200 210
310 320 330 340 350 360
pF1KE2 RKTRDQYLMWLTQKGVRQKKLNEWLGNENTEDQYSLVEDDEDLPHHDEKTWNVGSSNRNK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RKTRDQYLMWLTQKGVRQKKLNEWLGNENTEDQYSLVEDDEDLPHHDEKTWNVGSSNRNK
220 230 240 250 260 270
370 380 390 400 410 420
pF1KE2 AENLLRGKRDGTFLVRESSKQGCYACSVVVDGEVKHCVINKTATGYGFAEPYNLYSSLKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AENLLRGKRDGTFLVRESSKQGCYACSVVVDGEVKHCVINKTATGYGFAEPYNLYSSLKE
280 290 300 310 320 330
430 440 450
pF1KE2 LVLHYQHTSLVQHNDSLNVTLAYPVYAQQRR
:::::::::::::::::::::::::::::::
NP_001 LVLHYQHTSLVQHNDSLNVTLAYPVYAQQRR
340 350 360
>>NP_001107644 (OMIM: 606076) phosphatidylinositol 3-kin (461 aa)
initn: 1576 init1: 1576 opt: 2374 Z-score: 1630.8 bits: 311.0 E(92320): 4.6e-84
Smith-Waterman score: 2374; 77.8% identity (92.5% similar) in 455 aa overlap (1-451:1-455)
10 20 30 40 50
pF1KE2 MYNTVWNMEDLDLEYAKTDINCGTDLMFYIEMDPPALPPKPPKPTTVA-NNGM-NNNMSL
::::::.:. : .. .. . .:.:.::::::::::::::::: : : ::: ....::
NP_001 MYNTVWSMDRDDADWREVMMPYSTELIFYIEMDPPALPPKPPKPMTSAVPNGMKDSSVSL
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE2 QDAEWYWGDISREEVNEKLRDTADGTFLVRDASTKMHGDYTLTLRKGGNNKLIKIFHRDG
::::::::::::::::.:::: :::::::::::::.::::::::::::::::::.::::
NP_001 QDAEWYWGDISREEVNDKLRDMPDGTFLVRDASTKMQGDYTLTLRKGGNNKLIKIYHRDG
70 80 90 100 110 120
120 130 140 150 160 170
pF1KE2 KYGFSDPLTFSSVVELINHYRNESLAQYNPKLDVKLLYPVSKYQQDQVVKEDNIEAVGKK
::::::::::.:::::::::..::::::::::::::.::::.:::::.::::::.:::::
NP_001 KYGFSDPLTFNSVVELINHYHHESLAQYNPKLDVKLMYPVSRYQQDQLVKEDNIDAVGKK
130 140 150 160 170 180
180 190 200 210 220 230
pF1KE2 LHKYNTQFQEKSREYDRLYEEYTRTSQEIQMKRTAIEAFNETIKIFEEQCQTQERYSKEY
:..:..:.::::.:::::::::::::::::::::::::::::::::::::.:::..::::
NP_001 LQEYHSQYQEKSKEYDRLYEEYTRTSQEIQMKRTAIEAFNETIKIFEEQCHTQEQHSKEY
190 200 210 220 230 240
240 250 260 270 280 290
pF1KE2 IEKFKREGNEKEIQRIMHNYDKLKSRISEIIDSRRRLEEDLKKQAAEYREIDKRMNSIKP
::.:.::::::::.::: ::::::::..:: ::. :::.:::.:: . :::::.::::::
NP_001 IERFRREGNEKEIERIMMNYDKLKSRLGEIHDSKMRLEQDLKNQALDNREIDKKMNSIKP
250 260 270 280 290 300
300 310 320 330 340 350
pF1KE2 DLIQLRKTRDQYLMWLTQKGVRQKKLNEWLG--NENTEDQYSLVEDDEDLPHHDEKTWNV
::::::: :::.:.::..::::::.:: ::: ::.....: . :.::.:::.::::: :
NP_001 DLIQLRKIRDQHLVWLNHKGVRQKRLNVWLGIKNEDADENYFINEEDENLPHYDEKTWFV
310 320 330 340 350 360
360 370 380 390 400 410
pF1KE2 GSSNRNKAENLLRGKRDGTFLVRESSKQGCYACSVVVDGEVKHCVINKTATGYGFAEPYN
. :: .::.:: :: ::.::.:::::.::::::::.::::::::: .:: :::::::::
NP_001 EDINRVQAEDLLYGKPDGAFLIRESSKKGCYACSVVADGEVKHCVIYSTARGYGFAEPYN
370 380 390 400 410 420
420 430 440 450
pF1KE2 LYSSLKELVLHYQHTSLVQHNDSLNVTLAYPVYAQQRR
:::::::::::::.:::::::::::: :::::.::
NP_001 LYSSLKELVLHYQQTSLVQHNDSLNVRLAYPVHAQMPSLCR
430 440 450 460
>>NP_003620 (OMIM: 606076) phosphatidylinositol 3-kinase (461 aa)
initn: 1576 init1: 1576 opt: 2374 Z-score: 1630.8 bits: 311.0 E(92320): 4.6e-84
Smith-Waterman score: 2374; 77.8% identity (92.5% similar) in 455 aa overlap (1-451:1-455)
10 20 30 40 50
pF1KE2 MYNTVWNMEDLDLEYAKTDINCGTDLMFYIEMDPPALPPKPPKPTTVA-NNGM-NNNMSL
::::::.:. : .. .. . .:.:.::::::::::::::::: : : ::: ....::
NP_003 MYNTVWSMDRDDADWREVMMPYSTELIFYIEMDPPALPPKPPKPMTSAVPNGMKDSSVSL
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE2 QDAEWYWGDISREEVNEKLRDTADGTFLVRDASTKMHGDYTLTLRKGGNNKLIKIFHRDG
::::::::::::::::.:::: :::::::::::::.::::::::::::::::::.::::
NP_003 QDAEWYWGDISREEVNDKLRDMPDGTFLVRDASTKMQGDYTLTLRKGGNNKLIKIYHRDG
70 80 90 100 110 120
120 130 140 150 160 170
pF1KE2 KYGFSDPLTFSSVVELINHYRNESLAQYNPKLDVKLLYPVSKYQQDQVVKEDNIEAVGKK
::::::::::.:::::::::..::::::::::::::.::::.:::::.::::::.:::::
NP_003 KYGFSDPLTFNSVVELINHYHHESLAQYNPKLDVKLMYPVSRYQQDQLVKEDNIDAVGKK
130 140 150 160 170 180
180 190 200 210 220 230
pF1KE2 LHKYNTQFQEKSREYDRLYEEYTRTSQEIQMKRTAIEAFNETIKIFEEQCQTQERYSKEY
:..:..:.::::.:::::::::::::::::::::::::::::::::::::.:::..::::
NP_003 LQEYHSQYQEKSKEYDRLYEEYTRTSQEIQMKRTAIEAFNETIKIFEEQCHTQEQHSKEY
190 200 210 220 230 240
240 250 260 270 280 290
pF1KE2 IEKFKREGNEKEIQRIMHNYDKLKSRISEIIDSRRRLEEDLKKQAAEYREIDKRMNSIKP
::.:.::::::::.::: ::::::::..:: ::. :::.:::.:: . :::::.::::::
NP_003 IERFRREGNEKEIERIMMNYDKLKSRLGEIHDSKMRLEQDLKNQALDNREIDKKMNSIKP
250 260 270 280 290 300
300 310 320 330 340 350
pF1KE2 DLIQLRKTRDQYLMWLTQKGVRQKKLNEWLG--NENTEDQYSLVEDDEDLPHHDEKTWNV
::::::: :::.:.::..::::::.:: ::: ::.....: . :.::.:::.::::: :
NP_003 DLIQLRKIRDQHLVWLNHKGVRQKRLNVWLGIKNEDADENYFINEEDENLPHYDEKTWFV
310 320 330 340 350 360
360 370 380 390 400 410
pF1KE2 GSSNRNKAENLLRGKRDGTFLVRESSKQGCYACSVVVDGEVKHCVINKTATGYGFAEPYN
. :: .::.:: :: ::.::.:::::.::::::::.::::::::: .:: :::::::::
NP_003 EDINRVQAEDLLYGKPDGAFLIRESSKKGCYACSVVADGEVKHCVIYSTARGYGFAEPYN
370 380 390 400 410 420
420 430 440 450
pF1KE2 LYSSLKELVLHYQHTSLVQHNDSLNVTLAYPVYAQQRR
:::::::::::::.:::::::::::: :::::.::
NP_003 LYSSLKELVLHYQQTSLVQHNDSLNVRLAYPVHAQMPSLCR
430 440 450 460
454 residues in 1 query sequences
64369986 residues in 92320 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Thu Oct 24 21:39:44 2019 done: Thu Oct 24 21:39:45 2019
Total Scan time: 4.560 Total Display time: 0.060
Function used was FASTA [36.3.4 Apr, 2011]