Result of FASTA (omim) for
pFN21AE1227
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE1227, 313 aa
1>>>pF1KE1227 313 - 313 aa - 313 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 6.0962+/-0.000567; mu= 12.0871+/- 0.035
mean_var=156.5635+/-35.315, 0's: 0 Z-trim(110.3): 335 B-trim: 257 in 1/51
Lambda= 0.102501
statistics sampled from 18205 (18658) to 18205 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.577), E-opt: 0.2 (0.219), width: 16
Scan time: 5.000
The best scores are: opt bits E(85289)
NP_079498 (OMIM: 611059) WD repeat-containing prot ( 313) 2112 325.0 1.3e-88
XP_011532438 (OMIM: 611059) PREDICTED: WD repeat-c ( 233) 1547 241.2 1.5e-63
NP_438172 (OMIM: 609012) WD repeat-containing prot ( 334) 401 72.0 1.9e-12
XP_005272220 (OMIM: 609012) PREDICTED: WD repeat-c ( 334) 401 72.0 1.9e-12
NP_060058 (OMIM: 609012) WD repeat-containing prot ( 334) 401 72.0 1.9e-12
NP_005264 (OMIM: 139390) guanine nucleotide-bindin ( 340) 288 55.3 2.1e-07
XP_005247749 (OMIM: 610863,615185) PREDICTED: guan ( 340) 287 55.1 2.3e-07
XP_006713784 (OMIM: 610863,615185) PREDICTED: guan ( 340) 287 55.1 2.3e-07
NP_067642 (OMIM: 610863,615185) guanine nucleotide ( 340) 287 55.1 2.3e-07
NP_942593 (OMIM: 610767,611081) autophagy-related ( 444) 280 54.2 5.6e-07
XP_005246143 (OMIM: 610767,611081) PREDICTED: auto ( 463) 280 54.3 5.7e-07
XP_005246141 (OMIM: 610767,611081) PREDICTED: auto ( 480) 280 54.3 5.9e-07
NP_001177196 (OMIM: 610767,611081) autophagy-relat ( 491) 280 54.3 6e-07
NP_001177195 (OMIM: 610767,611081) autophagy-relat ( 523) 280 54.3 6.2e-07
XP_006712671 (OMIM: 610767,611081) PREDICTED: auto ( 540) 280 54.3 6.3e-07
NP_001269467 (OMIM: 139380,613065,616973) guanine ( 240) 275 53.2 6.4e-07
NP_060444 (OMIM: 610767,611081) autophagy-related ( 588) 280 54.4 6.7e-07
NP_110430 (OMIM: 610767,611081) autophagy-related ( 607) 280 54.4 6.8e-07
XP_005246139 (OMIM: 610767,611081) PREDICTED: auto ( 624) 280 54.4 6.9e-07
NP_001269468 (OMIM: 139380,613065,616973) guanine ( 340) 275 53.3 7.9e-07
XP_016856549 (OMIM: 139380,613065,616973) PREDICTE ( 340) 275 53.3 7.9e-07
XP_016856550 (OMIM: 139380,613065,616973) PREDICTE ( 340) 275 53.3 7.9e-07
XP_016856548 (OMIM: 139380,613065,616973) PREDICTE ( 340) 275 53.3 7.9e-07
NP_002065 (OMIM: 139380,613065,616973) guanine nuc ( 340) 275 53.3 7.9e-07
NP_001093207 (OMIM: 616850) WD repeat domain-conta ( 315) 251 49.8 8.8e-06
NP_115708 (OMIM: 616850) WD repeat domain-containi ( 315) 251 49.8 8.8e-06
NP_001284500 (OMIM: 139130,145500,617024) guanine ( 339) 245 48.9 1.7e-05
NP_002066 (OMIM: 139130,145500,617024) guanine nuc ( 340) 245 48.9 1.7e-05
NP_008882 (OMIM: 601787) transcription initiation ( 800) 244 49.2 3.2e-05
NP_001132939 (OMIM: 300196) F-box-like/WD repeat-c ( 526) 232 47.2 8.5e-05
NP_001132940 (OMIM: 300196) F-box-like/WD repeat-c ( 526) 232 47.2 8.5e-05
XP_011543873 (OMIM: 300196) PREDICTED: F-box-like/ ( 526) 232 47.2 8.5e-05
NP_001132938 (OMIM: 300196) F-box-like/WD repeat-c ( 577) 232 47.3 9e-05
NP_005638 (OMIM: 300196) F-box-like/WD repeat-cont ( 577) 232 47.3 9e-05
XP_016885576 (OMIM: 400033) PREDICTED: F-box-like/ ( 540) 230 46.9 0.00011
XP_016885575 (OMIM: 400033) PREDICTED: F-box-like/ ( 577) 230 47.0 0.00011
NP_005877 (OMIM: 602703,616212) katanin p80 WD40 r ( 655) 229 46.9 0.00013
XP_016878352 (OMIM: 602703,616212) PREDICTED: kata ( 655) 229 46.9 0.00013
XP_016878353 (OMIM: 602703,616212) PREDICTED: kata ( 655) 229 46.9 0.00013
XP_006721186 (OMIM: 602703,616212) PREDICTED: kata ( 658) 229 46.9 0.00013
XP_016878350 (OMIM: 602703,616212) PREDICTED: kata ( 672) 229 46.9 0.00014
XP_005255829 (OMIM: 602703,616212) PREDICTED: kata ( 672) 229 46.9 0.00014
XP_016878351 (OMIM: 602703,616212) PREDICTED: kata ( 672) 229 46.9 0.00014
XP_016878349 (OMIM: 602703,616212) PREDICTED: kata ( 675) 229 46.9 0.00014
XP_006721185 (OMIM: 602703,616212) PREDICTED: kata ( 675) 229 46.9 0.00014
XP_011521112 (OMIM: 602703,616212) PREDICTED: kata ( 675) 229 46.9 0.00014
XP_006721184 (OMIM: 602703,616212) PREDICTED: kata ( 675) 229 46.9 0.00014
NP_599021 (OMIM: 400033) F-box-like/WD repeat-cont ( 522) 223 45.9 0.00021
NP_599020 (OMIM: 400033) F-box-like/WD repeat-cont ( 522) 223 45.9 0.00021
NP_150600 (OMIM: 400033) F-box-like/WD repeat-cont ( 522) 223 45.9 0.00021
>>NP_079498 (OMIM: 611059) WD repeat-containing protein (313 aa)
initn: 2112 init1: 2112 opt: 2112 Z-score: 1712.1 bits: 325.0 E(85289): 1.3e-88
Smith-Waterman score: 2112; 100.0% identity (100.0% similar) in 313 aa overlap (1-313:1-313)
10 20 30 40 50 60
pF1KE1 MKLTDSVLRSFRVAKVFRENSDKINCFDFSPNGETVISSSDDDSIVLYDCQEGKPKRTLY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_079 MKLTDSVLRSFRVAKVFRENSDKINCFDFSPNGETVISSSDDDSIVLYDCQEGKPKRTLY
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 SKKYGVDLIRYTHAANTVVYSSNKIDDTIRYLSLHDNKYIRYFPGHSKRVVALSMSPVDD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_079 SKKYGVDLIRYTHAANTVVYSSNKIDDTIRYLSLHDNKYIRYFPGHSKRVVALSMSPVDD
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 TFISGSLDKTIRLWDLRSPNCQGLMHLQGKPVCSFDPEGLIFAAGVNSEMVKLYDLRSFD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_079 TFISGSLDKTIRLWDLRSPNCQGLMHLQGKPVCSFDPEGLIFAAGVNSEMVKLYDLRSFD
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 KGPFATFKMQYDRTCEWTGLKFSNDGKLILISTNGSFIRLIDAFKGVVMHTFGGYANSKA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_079 KGPFATFKMQYDRTCEWTGLKFSNDGKLILISTNGSFIRLIDAFKGVVMHTFGGYANSKA
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE1 VTLEASFTPDSQFIMIGSEDGKIHVWNGESGIKVAVLDGKHTGPITCLQFNPKFMTFASA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_079 VTLEASFTPDSQFIMIGSEDGKIHVWNGESGIKVAVLDGKHTGPITCLQFNPKFMTFASA
250 260 270 280 290 300
310
pF1KE1 CSNMAFWLPTIDD
:::::::::::::
NP_079 CSNMAFWLPTIDD
310
>>XP_011532438 (OMIM: 611059) PREDICTED: WD repeat-conta (233 aa)
initn: 1547 init1: 1547 opt: 1547 Z-score: 1262.0 bits: 241.2 E(85289): 1.5e-63
Smith-Waterman score: 1547; 99.6% identity (100.0% similar) in 227 aa overlap (87-313:7-233)
60 70 80 90 100 110
pF1KE1 RTLYSKKYGVDLIRYTHAANTVVYSSNKIDDTIRYLSLHDNKYIRYFPGHSKRVVALSMS
.:::::::::::::::::::::::::::::
XP_011 MTARRANTIRYLSLHDNKYIRYFPGHSKRVVALSMS
10 20 30
120 130 140 150 160 170
pF1KE1 PVDDTFISGSLDKTIRLWDLRSPNCQGLMHLQGKPVCSFDPEGLIFAAGVNSEMVKLYDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PVDDTFISGSLDKTIRLWDLRSPNCQGLMHLQGKPVCSFDPEGLIFAAGVNSEMVKLYDL
40 50 60 70 80 90
180 190 200 210 220 230
pF1KE1 RSFDKGPFATFKMQYDRTCEWTGLKFSNDGKLILISTNGSFIRLIDAFKGVVMHTFGGYA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RSFDKGPFATFKMQYDRTCEWTGLKFSNDGKLILISTNGSFIRLIDAFKGVVMHTFGGYA
100 110 120 130 140 150
240 250 260 270 280 290
pF1KE1 NSKAVTLEASFTPDSQFIMIGSEDGKIHVWNGESGIKVAVLDGKHTGPITCLQFNPKFMT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NSKAVTLEASFTPDSQFIMIGSEDGKIHVWNGESGIKVAVLDGKHTGPITCLQFNPKFMT
160 170 180 190 200 210
300 310
pF1KE1 FASACSNMAFWLPTIDD
:::::::::::::::::
XP_011 FASACSNMAFWLPTIDD
220 230
>>NP_438172 (OMIM: 609012) WD repeat-containing protein (334 aa)
initn: 380 init1: 149 opt: 401 Z-score: 344.4 bits: 72.0 E(85289): 1.9e-12
Smith-Waterman score: 401; 27.1% identity (60.2% similar) in 284 aa overlap (20-300:44-319)
10 20 30 40
pF1KE1 MKLTDSVLRSFRVAKVFRENSDKINCFDFSPNGETVISSSDDDSIVLYD
.. .. :::::: . ::: : : ..
NP_438 RAQPTPSSSATQSKPTPVKPNYALKFTLAGHTKAVSSVKFSPNGEWLASSSADKLIKIWG
20 30 40 50 60 70
50 60 70 80 90 100
pF1KE1 CQEGKPKRTLYSKKYGVDLIRYTHAANTVVYSSNKIDDTIRYLSLHDNKYIRYFPGHSKR
.:: ..:. ..: :.. . .. .: .: .:. : :.. .. ..: .. . :::.
NP_438 AYDGKFEKTISGHKLGISDVAWSSDSNLLVSASD--DKTLKIWDVSSGKCLKTLKGHSNY
80 90 100 110 120 130
110 120 130 140 150 160
pF1KE1 VVALSMSPVDDTFISGSLDKTIRLWDLRSPNCQGLMHLQGKPVCS--FDPEGLIFAAGVN
: ...: .. ..:::.:...:.::... .: . .. :: . :. .: .....
NP_438 VFCCNFNPQSNLIVSGSFDESVRIWDVKTGKCLKTLPAHSDPVSAVHFNRDGSLIVSSSY
140 150 160 170 180 190
170 180 190 200 210 220
pF1KE1 SEMVKLYDLRSFDKGPFATFKMQYDRTCEWTGLKFSNDGKLILISTNGSFIRLIDAFKGV
. . ...: : : .. : . .::: .:: :: .: . ..: : ::
NP_438 DGLCRIWDTAS---GQCLKTLIDDDNP-PVSFVKFSPNGKYILAATLDNTLKLWDYSKGK
200 210 220 230 240
230 240 250 260 270 280
pF1KE1 VMHTFGGYANSKAVTLEASFT-PDSQFIMIGSEDGKIHVWNGESGIKVAVLDGKHTGPIT
..:. :. : : . :.:. ...:. ::::. ...:: .. : :.: :: .
NP_438 CLKTYTGHKNEK-YCIFANFSVTGGKWIVSGSEDNLVYIWNLQTKEIVQKLQG-HTDVVI
250 260 270 280 290 300
290 300 310
pF1KE1 CLQFNPKFMTFASACSNMAFWLPTIDD
.: .:::
NP_438 STACHPTENIIASAALENDKTIKLWKSDC
310 320 330
>>XP_005272220 (OMIM: 609012) PREDICTED: WD repeat-conta (334 aa)
initn: 380 init1: 149 opt: 401 Z-score: 344.4 bits: 72.0 E(85289): 1.9e-12
Smith-Waterman score: 401; 27.1% identity (60.2% similar) in 284 aa overlap (20-300:44-319)
10 20 30 40
pF1KE1 MKLTDSVLRSFRVAKVFRENSDKINCFDFSPNGETVISSSDDDSIVLYD
.. .. :::::: . ::: : : ..
XP_005 RAQPTPSSSATQSKPTPVKPNYALKFTLAGHTKAVSSVKFSPNGEWLASSSADKLIKIWG
20 30 40 50 60 70
50 60 70 80 90 100
pF1KE1 CQEGKPKRTLYSKKYGVDLIRYTHAANTVVYSSNKIDDTIRYLSLHDNKYIRYFPGHSKR
.:: ..:. ..: :.. . .. .: .: .:. : :.. .. ..: .. . :::.
XP_005 AYDGKFEKTISGHKLGISDVAWSSDSNLLVSASD--DKTLKIWDVSSGKCLKTLKGHSNY
80 90 100 110 120 130
110 120 130 140 150 160
pF1KE1 VVALSMSPVDDTFISGSLDKTIRLWDLRSPNCQGLMHLQGKPVCS--FDPEGLIFAAGVN
: ...: .. ..:::.:...:.::... .: . .. :: . :. .: .....
XP_005 VFCCNFNPQSNLIVSGSFDESVRIWDVKTGKCLKTLPAHSDPVSAVHFNRDGSLIVSSSY
140 150 160 170 180 190
170 180 190 200 210 220
pF1KE1 SEMVKLYDLRSFDKGPFATFKMQYDRTCEWTGLKFSNDGKLILISTNGSFIRLIDAFKGV
. . ...: : : .. : . .::: .:: :: .: . ..: : ::
XP_005 DGLCRIWDTAS---GQCLKTLIDDDNP-PVSFVKFSPNGKYILAATLDNTLKLWDYSKGK
200 210 220 230 240
230 240 250 260 270 280
pF1KE1 VMHTFGGYANSKAVTLEASFT-PDSQFIMIGSEDGKIHVWNGESGIKVAVLDGKHTGPIT
..:. :. : : . :.:. ...:. ::::. ...:: .. : :.: :: .
XP_005 CLKTYTGHKNEK-YCIFANFSVTGGKWIVSGSEDNLVYIWNLQTKEIVQKLQG-HTDVVI
250 260 270 280 290 300
290 300 310
pF1KE1 CLQFNPKFMTFASACSNMAFWLPTIDD
.: .:::
XP_005 STACHPTENIIASAALENDKTIKLWKSDC
310 320 330
>>NP_060058 (OMIM: 609012) WD repeat-containing protein (334 aa)
initn: 380 init1: 149 opt: 401 Z-score: 344.4 bits: 72.0 E(85289): 1.9e-12
Smith-Waterman score: 401; 27.1% identity (60.2% similar) in 284 aa overlap (20-300:44-319)
10 20 30 40
pF1KE1 MKLTDSVLRSFRVAKVFRENSDKINCFDFSPNGETVISSSDDDSIVLYD
.. .. :::::: . ::: : : ..
NP_060 RAQPTPSSSATQSKPTPVKPNYALKFTLAGHTKAVSSVKFSPNGEWLASSSADKLIKIWG
20 30 40 50 60 70
50 60 70 80 90 100
pF1KE1 CQEGKPKRTLYSKKYGVDLIRYTHAANTVVYSSNKIDDTIRYLSLHDNKYIRYFPGHSKR
.:: ..:. ..: :.. . .. .: .: .:. : :.. .. ..: .. . :::.
NP_060 AYDGKFEKTISGHKLGISDVAWSSDSNLLVSASD--DKTLKIWDVSSGKCLKTLKGHSNY
80 90 100 110 120 130
110 120 130 140 150 160
pF1KE1 VVALSMSPVDDTFISGSLDKTIRLWDLRSPNCQGLMHLQGKPVCS--FDPEGLIFAAGVN
: ...: .. ..:::.:...:.::... .: . .. :: . :. .: .....
NP_060 VFCCNFNPQSNLIVSGSFDESVRIWDVKTGKCLKTLPAHSDPVSAVHFNRDGSLIVSSSY
140 150 160 170 180 190
170 180 190 200 210 220
pF1KE1 SEMVKLYDLRSFDKGPFATFKMQYDRTCEWTGLKFSNDGKLILISTNGSFIRLIDAFKGV
. . ...: : : .. : . .::: .:: :: .: . ..: : ::
NP_060 DGLCRIWDTAS---GQCLKTLIDDDNP-PVSFVKFSPNGKYILAATLDNTLKLWDYSKGK
200 210 220 230 240
230 240 250 260 270 280
pF1KE1 VMHTFGGYANSKAVTLEASFT-PDSQFIMIGSEDGKIHVWNGESGIKVAVLDGKHTGPIT
..:. :. : : . :.:. ...:. ::::. ...:: .. : :.: :: .
NP_060 CLKTYTGHKNEK-YCIFANFSVTGGKWIVSGSEDNLVYIWNLQTKEIVQKLQG-HTDVVI
250 260 270 280 290 300
290 300 310
pF1KE1 CLQFNPKFMTFASACSNMAFWLPTIDD
.: .:::
NP_060 STACHPTENIIASAALENDKTIKLWKSDC
310 320 330
>>NP_005264 (OMIM: 139390) guanine nucleotide-binding pr (340 aa)
initn: 286 init1: 136 opt: 288 Z-score: 254.0 bits: 55.3 E(85289): 2.1e-07
Smith-Waterman score: 288; 27.5% identity (57.8% similar) in 251 aa overlap (24-267:101-340)
10 20 30 40 50
pF1KE1 MKLTDSVLRSFRVAKVFRENSDKINCFDFSPNGETVISSSDDD--SIVLYDCQ
..: ..:.:. : .. :. :: .
NP_005 VSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTC-AYAPSGNFVACGGLDNICSIYSLKTR
80 90 100 110 120
60 70 80 90 100
pF1KE1 EGKPK--RTLYSKKYGVDLIRYTHAANTVVYSSNKIDDTIRYLSLHDNKYIRYFPGHSKR
::. . : : .. .. :. : .. ::. : : ... .. : :::
NP_005 EGNVRVSRELPGHTGYLSCCRFLDD-NQIITSSG--DTTCALWDIETGQQTVGFAGHSGD
130 140 150 160 170 180
110 120 130 140 150 160
pF1KE1 VVALSMSPVDDTFISGSLDKTIRLWDLRSPNCQGLM--HLQGKPVCSFDPEGLIFAAGVN
:..::..: ::.::. : .:.:::.:. :. . : . . .: :.: :..: .
NP_005 VMSLSLAPDGRTFVSGACDASIKLWDVRDSMCRQTFIGHESDINAVAFFPNGYAFTTGSD
190 200 210 220 230 240
170 180 190 200 210 220
pF1KE1 SEMVKLYDLRSFDKGPFATFKMQYDRT-CEWTGLKFSNDGKLILISTNGSFIRLIDAFKG
. .:.:::. :. . ...: : :.. :: .:.:.: . . . ::.::
NP_005 DATCRLFDLRA-DQ---ELLMYSHDNIICGITSVAFSRSGRLLLAGYDDFNCNIWDAMKG
250 260 270 280 290 300
230 240 250 260 270 280
pF1KE1 VVMHTFGGYANSKAVTLEASFTPDSQFIMIGSEDGKIHVWNGESGIKVAVLDGKHTGPIT
...:. : .. : . : :.. . :: :. ...::
NP_005 DRAGVLAGHDN-RVSCL--GVTDDGMAVATGSWDSFLKIWN
310 320 330 340
290 300 310
pF1KE1 CLQFNPKFMTFASACSNMAFWLPTIDD
>>XP_005247749 (OMIM: 610863,615185) PREDICTED: guanine (340 aa)
initn: 242 init1: 129 opt: 287 Z-score: 253.2 bits: 55.1 E(85289): 2.3e-07
Smith-Waterman score: 287; 27.9% identity (59.0% similar) in 251 aa overlap (24-267:101-340)
10 20 30 40 50
pF1KE1 MKLTDSVLRSFRVAKVFRENSDKINCFDFSPNGETVISSSDDDSIVLYDCQ--
..: ..:.:. : .. :. .:. .
XP_005 VSASQDGKLIIWDSYTTNKMHAIPLRSSWVMTC-AYAPSGNYVACGGLDNICSIYNLKTR
80 90 100 110 120
60 70 80 90 100
pF1KE1 EGKPK--RTLYSKKYGVDLIRYTHAANTVVYSSNKIDDTIRYLSLHDNKYIRYFPGHSKR
::. . : : .. .. :. .. .: ::. : : ... . : :::
XP_005 EGNVRVSRELPGHTGYLSCCRFLDDSQ-IVTSSG--DTTCALWDIETAQQTTTFTGHSGD
130 140 150 160 170 180
110 120 130 140 150 160
pF1KE1 VVALSMSPVDDTFISGSLDKTIRLWDLRSPNC-QGLM-HLQGKPVCSFDPEGLIFAAGVN
:..::.:: ::.::. : . .:::.:. : :.. :.. . :: :.: ::.: .
XP_005 VMSLSLSPDMRTFVSGACDASSKLWDIRDGMCRQSFTGHVSDINAVSFFPNGYAFATGSD
190 200 210 220 230 240
170 180 190 200 210 220
pF1KE1 SEMVKLYDLRSFDKGPFATFKMQYDRT-CEWTGLKFSNDGKLILISTNGSFIRLIDAFKG
. .:.:::. :. . ...: : :.. ::..:.:.: . . . :..::
XP_005 DATCRLFDLRA-DQ---ELLLYSHDNIICGITSVAFSKSGRLLLAGYDDFNCNVWDTLKG
250 260 270 280 290 300
230 240 250 260 270 280
pF1KE1 VVMHTFGGYANSKAVTLEASFTPDSQFIMIGSEDGKIHVWNGESGIKVAVLDGKHTGPIT
...:. : .. : . : :.. . :: :. ...::
XP_005 DRAGVLAGHDN-RVSCL--GVTDDGMAVATGSWDSFLRIWN
310 320 330 340
290 300 310
pF1KE1 CLQFNPKFMTFASACSNMAFWLPTIDD
>>XP_006713784 (OMIM: 610863,615185) PREDICTED: guanine (340 aa)
initn: 242 init1: 129 opt: 287 Z-score: 253.2 bits: 55.1 E(85289): 2.3e-07
Smith-Waterman score: 287; 27.9% identity (59.0% similar) in 251 aa overlap (24-267:101-340)
10 20 30 40 50
pF1KE1 MKLTDSVLRSFRVAKVFRENSDKINCFDFSPNGETVISSSDDDSIVLYDCQ--
..: ..:.:. : .. :. .:. .
XP_006 VSASQDGKLIIWDSYTTNKMHAIPLRSSWVMTC-AYAPSGNYVACGGLDNICSIYNLKTR
80 90 100 110 120
60 70 80 90 100
pF1KE1 EGKPK--RTLYSKKYGVDLIRYTHAANTVVYSSNKIDDTIRYLSLHDNKYIRYFPGHSKR
::. . : : .. .. :. .. .: ::. : : ... . : :::
XP_006 EGNVRVSRELPGHTGYLSCCRFLDDSQ-IVTSSG--DTTCALWDIETAQQTTTFTGHSGD
130 140 150 160 170 180
110 120 130 140 150 160
pF1KE1 VVALSMSPVDDTFISGSLDKTIRLWDLRSPNC-QGLM-HLQGKPVCSFDPEGLIFAAGVN
:..::.:: ::.::. : . .:::.:. : :.. :.. . :: :.: ::.: .
XP_006 VMSLSLSPDMRTFVSGACDASSKLWDIRDGMCRQSFTGHVSDINAVSFFPNGYAFATGSD
190 200 210 220 230 240
170 180 190 200 210 220
pF1KE1 SEMVKLYDLRSFDKGPFATFKMQYDRT-CEWTGLKFSNDGKLILISTNGSFIRLIDAFKG
. .:.:::. :. . ...: : :.. ::..:.:.: . . . :..::
XP_006 DATCRLFDLRA-DQ---ELLLYSHDNIICGITSVAFSKSGRLLLAGYDDFNCNVWDTLKG
250 260 270 280 290 300
230 240 250 260 270 280
pF1KE1 VVMHTFGGYANSKAVTLEASFTPDSQFIMIGSEDGKIHVWNGESGIKVAVLDGKHTGPIT
...:. : .. : . : :.. . :: :. ...::
XP_006 DRAGVLAGHDN-RVSCL--GVTDDGMAVATGSWDSFLRIWN
310 320 330 340
290 300 310
pF1KE1 CLQFNPKFMTFASACSNMAFWLPTIDD
>>NP_067642 (OMIM: 610863,615185) guanine nucleotide-bin (340 aa)
initn: 242 init1: 129 opt: 287 Z-score: 253.2 bits: 55.1 E(85289): 2.3e-07
Smith-Waterman score: 287; 27.9% identity (59.0% similar) in 251 aa overlap (24-267:101-340)
10 20 30 40 50
pF1KE1 MKLTDSVLRSFRVAKVFRENSDKINCFDFSPNGETVISSSDDDSIVLYDCQ--
..: ..:.:. : .. :. .:. .
NP_067 VSASQDGKLIIWDSYTTNKMHAIPLRSSWVMTC-AYAPSGNYVACGGLDNICSIYNLKTR
80 90 100 110 120
60 70 80 90 100
pF1KE1 EGKPK--RTLYSKKYGVDLIRYTHAANTVVYSSNKIDDTIRYLSLHDNKYIRYFPGHSKR
::. . : : .. .. :. .. .: ::. : : ... . : :::
NP_067 EGNVRVSRELPGHTGYLSCCRFLDDSQ-IVTSSG--DTTCALWDIETAQQTTTFTGHSGD
130 140 150 160 170 180
110 120 130 140 150 160
pF1KE1 VVALSMSPVDDTFISGSLDKTIRLWDLRSPNC-QGLM-HLQGKPVCSFDPEGLIFAAGVN
:..::.:: ::.::. : . .:::.:. : :.. :.. . :: :.: ::.: .
NP_067 VMSLSLSPDMRTFVSGACDASSKLWDIRDGMCRQSFTGHVSDINAVSFFPNGYAFATGSD
190 200 210 220 230 240
170 180 190 200 210 220
pF1KE1 SEMVKLYDLRSFDKGPFATFKMQYDRT-CEWTGLKFSNDGKLILISTNGSFIRLIDAFKG
. .:.:::. :. . ...: : :.. ::..:.:.: . . . :..::
NP_067 DATCRLFDLRA-DQ---ELLLYSHDNIICGITSVAFSKSGRLLLAGYDDFNCNVWDTLKG
250 260 270 280 290 300
230 240 250 260 270 280
pF1KE1 VVMHTFGGYANSKAVTLEASFTPDSQFIMIGSEDGKIHVWNGESGIKVAVLDGKHTGPIT
...:. : .. : . : :.. . :: :. ...::
NP_067 DRAGVLAGHDN-RVSCL--GVTDDGMAVATGSWDSFLRIWN
310 320 330 340
290 300 310
pF1KE1 CLQFNPKFMTFASACSNMAFWLPTIDD
>>NP_942593 (OMIM: 610767,611081) autophagy-related prot (444 aa)
initn: 243 init1: 111 opt: 280 Z-score: 246.3 bits: 54.2 E(85289): 5.6e-07
Smith-Waterman score: 280; 22.1% identity (60.7% similar) in 285 aa overlap (16-292:154-424)
10 20 30 40
pF1KE1 MKLTDSVLRSFRVAKVFRENSDKINCFDFSPNGETVISSSDDDSI
:: .. ..: .:::... . ... : .
NP_942 SVSSFPVPQDNVDTHPGSGKEVRVPATALCVFDAHDGEVNAVQFSPGSRLLATGGMDRRV
130 140 150 160 170 180
50 60 70 80 90 100
pF1KE1 VLYDC--QEGKPKRTLYSKKYGVDLIRYTHAANTVVYSSNKIDDTIRYLSLHDNKYIRYF
:.. .. . : .: ... :. :.. :.. .. .:: : . : .. : . . .
NP_942 KLWEVFGEKCEFKGSLSGSNAGITSIEFDSAGSYLLAASN--DFASRIWTVDDYRLRHTL
190 200 210 220 230 240
110 120 130 140 150
pF1KE1 PGHSKRVVALSMSPVDDTFISGSLDKTIRLWDLRSPNCQGLMHLQGKP----VCSFDPEG
::: .:.. .. . ..::: :.:..:::::: : . . :. ::. :
NP_942 TGHSGKVLSAKFLLDNARIVSGSHDRTLKLWDLRSKVCIKTV-FAGSSCNDIVCT---EQ
250 260 270 280 290
160 170 180 190 200 210
pF1KE1 LIFAAGVNSEMVKLYDLRSFDKGPFATFKMQYDRTCEWTGLKFSNDGKLILISTNGSFIR
.... ... ....:.:: .. ... . :.: .. . .: . ....
NP_942 CVMSGHFDKK-IRFWDIRS------ESIVREMELLGKITALDLNPERTELLSCSRDDLLK
300 310 320 330 340 350
220 230 240 250 260 270
pF1KE1 LIDAFKGVVMHTFG--GYANSKAVTLEASFTPDSQFIMIGSEDGKIHVWNGESGIKVAVL
.:: ... .::. :. .. : .. :.::.... :: .:....:. .: ::
NP_942 VIDLRTNAIKQTFSAPGFKCGSDWT-RVVFSPDGSYVAAGSAEGSLYIWSVLTGKVEKVL
360 370 380 390 400
280 290 300 310
pF1KE1 DGKHTGPITCLQFNPKFMTFASACSNMAFWLPTIDD
. .:.. :. . ..:
NP_942 SKQHSSSINAVAWSPSGSHVVSVDKGCKAVLWAQY
410 420 430 440
313 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 17:45:49 2016 done: Sun Nov 6 17:45:50 2016
Total Scan time: 5.000 Total Display time: 0.000
Function used was FASTA [36.3.4 Apr, 2011]