Result of FASTA (omim) for
pFN21AE0686
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE0686, 400 aa
1>>>pF1KE0686 400 - 400 aa - 400 aa
Library: /omim/omim.rfq.tfa
64369986 residues in 92320 sequences
Statistics: Expectation_n fit: rho(ln(x))= 12.2826+/-0.000446; mu= -11.3996+/- 0.028
mean_var=651.3030+/-138.115, 0's: 0 Z-trim(125.0): 1313 B-trim: 0 in 0/53
Lambda= 0.050255
statistics sampled from 47974 (49651) to 47974 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.798), E-opt: 0.2 (0.538), width: 16
Scan time: 4.760
The best scores are: opt bits E(92320)
NP_116584 (OMIM: 602006) MAP kinase-activated prot ( 400) 2729 212.4 1.7e-54
NP_004750 (OMIM: 602006) MAP kinase-activated prot ( 370) 2448 192.0 2.3e-48
XP_005273410 (OMIM: 602006) MAP kinase-activated p ( 371) 2448 192.0 2.3e-48
XP_016858299 (OMIM: 602006) MAP kinase-activated p ( 307) 2067 164.2 4.2e-40
NP_004626 (OMIM: 602130,617111) MAP kinase-activat ( 382) 1762 142.2 2.2e-33
NP_001230855 (OMIM: 602130,617111) MAP kinase-acti ( 382) 1762 142.2 2.2e-33
NP_001230854 (OMIM: 602130,617111) MAP kinase-acti ( 382) 1762 142.2 2.2e-33
XP_024304639 (OMIM: 601684) ribosomal protein S6 k ( 643) 697 65.3 5.2e-10
NP_001317370 (OMIM: 601684) ribosomal protein S6 k ( 719) 697 65.4 5.6e-10
NP_002944 (OMIM: 601684) ribosomal protein S6 kina ( 735) 697 65.4 5.7e-10
NP_001006666 (OMIM: 601684) ribosomal protein S6 k ( 744) 697 65.4 5.7e-10
NP_003647 (OMIM: 604998) calcium/calmodulin-depend ( 370) 652 61.7 3.6e-09
XP_005265573 (OMIM: 604998) calcium/calmodulin-dep ( 413) 652 61.8 3.8e-09
NP_001735 (OMIM: 114080) calcium/calmodulin-depend ( 473) 642 61.1 6.8e-09
NP_001310303 (OMIM: 114080) calcium/calmodulin-dep ( 473) 642 61.1 6.8e-09
NP_001310304 (OMIM: 114080) calcium/calmodulin-dep ( 473) 642 61.1 6.8e-09
XP_005274634 (OMIM: 300075,300844,303600) ribosoma ( 710) 646 61.7 7.2e-09
XP_006724570 (OMIM: 300075,300844,303600) ribosoma ( 711) 646 61.7 7.2e-09
XP_016885208 (OMIM: 300075,300844,303600) ribosoma ( 711) 646 61.7 7.2e-09
XP_005274630 (OMIM: 300075,300844,303600) ribosoma ( 739) 646 61.7 7.4e-09
XP_011543858 (OMIM: 300075,300844,303600) ribosoma ( 745) 646 61.7 7.4e-09
NP_065172 (OMIM: 614994) calcium/calmodulin-depend ( 476) 637 60.8 8.8e-09
XP_016857355 (OMIM: 614994) calcium/calmodulin-dep ( 476) 637 60.8 8.8e-09
XP_006717545 (OMIM: 607957) calcium/calmodulin-dep ( 362) 629 60.1 1.1e-08
XP_016885207 (OMIM: 300075,300844,303600) ribosoma ( 711) 635 60.9 1.3e-08
XP_016885204 (OMIM: 300075,300844,303600) ribosoma ( 712) 635 60.9 1.3e-08
XP_016885206 (OMIM: 300075,300844,303600) ribosoma ( 712) 635 60.9 1.3e-08
XP_016885205 (OMIM: 300075,300844,303600) ribosoma ( 712) 635 60.9 1.3e-08
XP_011543865 (OMIM: 300075,300844,303600) ribosoma ( 712) 635 60.9 1.3e-08
XP_016885202 (OMIM: 300075,300844,303600) ribosoma ( 712) 635 60.9 1.3e-08
XP_016885203 (OMIM: 300075,300844,303600) ribosoma ( 712) 635 60.9 1.3e-08
XP_011543864 (OMIM: 300075,300844,303600) ribosoma ( 717) 635 60.9 1.3e-08
XP_011543860 (OMIM: 300075,300844,303600) ribosoma ( 718) 635 60.9 1.3e-08
XP_011543859 (OMIM: 300075,300844,303600) ribosoma ( 718) 635 60.9 1.3e-08
XP_011543863 (OMIM: 300075,300844,303600) ribosoma ( 718) 635 60.9 1.3e-08
XP_011543862 (OMIM: 300075,300844,303600) ribosoma ( 718) 635 60.9 1.3e-08
XP_006717546 (OMIM: 607957) calcium/calmodulin-dep ( 355) 626 59.8 1.3e-08
NP_004577 (OMIM: 300075,300844,303600) ribosomal p ( 740) 635 60.9 1.3e-08
NP_065130 (OMIM: 607957) calcium/calmodulin-depend ( 357) 626 59.8 1.3e-08
XP_011543857 (OMIM: 300075,300844,303600) ribosoma ( 746) 635 60.9 1.3e-08
NP_705718 (OMIM: 607957) calcium/calmodulin-depend ( 385) 626 59.9 1.3e-08
XP_024309564 (OMIM: 604998) calcium/calmodulin-dep ( 308) 619 59.2 1.7e-08
XP_016862843 (OMIM: 604998) calcium/calmodulin-dep ( 326) 619 59.3 1.7e-08
XP_005265574 (OMIM: 604998) calcium/calmodulin-dep ( 369) 619 59.3 1.9e-08
NP_001305866 (OMIM: 601685) ribosomal protein S6 k ( 635) 619 59.6 2.6e-08
NP_001305867 (OMIM: 601685) ribosomal protein S6 k ( 644) 619 59.6 2.6e-08
XP_011517893 (OMIM: 607957) calcium/calmodulin-dep ( 372) 612 58.8 2.7e-08
NP_001034671 (OMIM: 300680) calcium/calmodulin-dep ( 426) 613 59.0 2.8e-08
XP_011517895 (OMIM: 607957) calcium/calmodulin-dep ( 311) 609 58.5 2.8e-08
XP_011517894 (OMIM: 607957) calcium/calmodulin-dep ( 315) 609 58.5 2.8e-08
>>NP_116584 (OMIM: 602006) MAP kinase-activated protein (400 aa)
initn: 2729 init1: 2729 opt: 2729 Z-score: 1099.8 bits: 212.4 E(92320): 1.7e-54
Smith-Waterman score: 2729; 100.0% identity (100.0% similar) in 400 aa overlap (1-400:1-400)
10 20 30 40 50 60
pF1KE0 MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAII
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_116 MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAII
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 DDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_116 DDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRI
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE0 VDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_116 VDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSI
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE0 NIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_116 NIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKY
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE0 DKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_116 DKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKM
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE0 LIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_116 LIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSAL
310 320 330 340 350 360
370 380 390 400
pF1KE0 ATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH
::::::::::::::::::::::::::::::::::::::::
NP_116 ATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH
370 380 390 400
>>NP_004750 (OMIM: 602006) MAP kinase-activated protein (370 aa)
initn: 2448 init1: 2448 opt: 2448 Z-score: 990.1 bits: 192.0 E(92320): 2.3e-48
Smith-Waterman score: 2448; 100.0% identity (100.0% similar) in 353 aa overlap (1-353:1-353)
10 20 30 40 50 60
pF1KE0 MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAII
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAII
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 DDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 DDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRI
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE0 VDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 VDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSI
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE0 NIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 NIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKY
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE0 DKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 DKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKM
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE0 LIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSAL
:::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 LIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKGCLHDKN
310 320 330 340 350 360
370 380 390 400
pF1KE0 ATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH
NP_004 SDQATWLTRL
370
>>XP_005273410 (OMIM: 602006) MAP kinase-activated prote (371 aa)
initn: 2448 init1: 2448 opt: 2448 Z-score: 990.1 bits: 192.0 E(92320): 2.3e-48
Smith-Waterman score: 2448; 100.0% identity (100.0% similar) in 353 aa overlap (1-353:1-353)
10 20 30 40 50 60
pF1KE0 MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAII
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAII
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 DDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRI
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE0 VDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSI
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE0 NIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 NIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKY
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE0 DKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKM
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE0 LIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSAL
:::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKGCLHDKN
310 320 330 340 350 360
370 380 390 400
pF1KE0 ATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH
XP_005 SDQATWLTRRR
370
>>XP_016858299 (OMIM: 602006) MAP kinase-activated prote (307 aa)
initn: 2067 init1: 2067 opt: 2067 Z-score: 841.7 bits: 164.2 E(92320): 4.2e-40
Smith-Waterman score: 2067; 100.0% identity (100.0% similar) in 307 aa overlap (94-400:1-307)
70 80 90 100 110 120
pF1KE0 KVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDV
::::::::::::::::::::::::::::::
XP_016 MLQDCPKARREVELHWRASQCPHIVRIVDV
10 20 30
130 140 150 160 170 180
pF1KE0 YENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIA
40 50 60 70 80 90
190 200 210 220 230 240
pF1KE0 HRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKS
100 110 120 130 140 150
250 260 270 280 290 300
pF1KE0 CDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIR
160 170 180 190 200 210
310 320 330 340 350 360
pF1KE0 NLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATM
220 230 240 250 260 270
370 380 390 400
pF1KE0 RVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH
:::::::::::::::::::::::::::::::::::::
XP_016 RVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH
280 290 300
>>NP_004626 (OMIM: 602130,617111) MAP kinase-activated p (382 aa)
initn: 1017 init1: 972 opt: 1762 Z-score: 721.1 bits: 142.2 E(92320): 2.2e-33
Smith-Waterman score: 1768; 70.7% identity (86.2% similar) in 369 aa overlap (21-389:12-368)
10 20 30 40 50 60
pF1KE0 MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAII
: :: :. : :. : .. : :: :.
NP_004 MDGETAEEQGGPVPP-PVAPGGPGLGGAPGGRREP----------KKYAVT
10 20 30 40
70 80 90 100 110 120
pF1KE0 DDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRI
:::....::::::.:::::. :..:: .: :::.: : ::::.::. ::.:: :::: :
NP_004 DDYQLSKQVLGLGVNGKVLECFHRRTGQKCALKLLYDSPKARQEVDHHWQASGGPHIVCI
50 60 70 80 90 100
130 140 150 160 170 180
pF1KE0 VDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSI
.:::::.. :..::::.:::..:::::::::.:::::::::::.:::..:: :::.:::
NP_004 LDVYENMHHGKRCLLIIMECMEGGELFSRIQERGDQAFTEREAAEIMRDIGTAIQFLHSH
110 120 130 140 150 160
190 200 210 220 230 240
pF1KE0 NIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKY
:::::::::::::::::. .:.::::::::::::: .:.: :::::::::::::::::::
NP_004 NIAHRDVKPENLLYTSKEKDAVLKLTDFGFAKETT-QNALQTPCYTPYYVAPEVLGPEKY
170 180 190 200 210
250 260 270 280 290 300
pF1KE0 DKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKM
:::::::::::::::::::.:::::: : ::::::: :::.::: :::::::::::..:.
NP_004 DKSCDMWSLGVIMYILLCGFPPFYSNTGQAISPGMKRRIRLGQYGFPNPEWSEVSEDAKQ
220 230 240 250 260 270
310 320 330 340 350 360
pF1KE0 LIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSAL
::: ::::.::.:.:::.::::::: :: ::::::::.:::.:::..:..:::::::::
NP_004 LIRLLLKTDPTERLTITQFMNHPWINQSMVVPQTPLHTARVLQEDKDHWDEVKEEMTSAL
280 290 300 310 320 330
370 380 390 400
pF1KE0 ATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH
:::::::.:.::: .. ..: :: :::::
NP_004 ATMRVDYDQVKIKDLKTSNNRLLNKRRKKQAGSSSASQGCNNQ
340 350 360 370 380
>>NP_001230855 (OMIM: 602130,617111) MAP kinase-activate (382 aa)
initn: 1017 init1: 972 opt: 1762 Z-score: 721.1 bits: 142.2 E(92320): 2.2e-33
Smith-Waterman score: 1768; 70.7% identity (86.2% similar) in 369 aa overlap (21-389:12-368)
10 20 30 40 50 60
pF1KE0 MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAII
: :: :. : :. : .. : :: :.
NP_001 MDGETAEEQGGPVPP-PVAPGGPGLGGAPGGRREP----------KKYAVT
10 20 30 40
70 80 90 100 110 120
pF1KE0 DDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRI
:::....::::::.:::::. :..:: .: :::.: : ::::.::. ::.:: :::: :
NP_001 DDYQLSKQVLGLGVNGKVLECFHRRTGQKCALKLLYDSPKARQEVDHHWQASGGPHIVCI
50 60 70 80 90 100
130 140 150 160 170 180
pF1KE0 VDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSI
.:::::.. :..::::.:::..:::::::::.:::::::::::.:::..:: :::.:::
NP_001 LDVYENMHHGKRCLLIIMECMEGGELFSRIQERGDQAFTEREAAEIMRDIGTAIQFLHSH
110 120 130 140 150 160
190 200 210 220 230 240
pF1KE0 NIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKY
:::::::::::::::::. .:.::::::::::::: .:.: :::::::::::::::::::
NP_001 NIAHRDVKPENLLYTSKEKDAVLKLTDFGFAKETT-QNALQTPCYTPYYVAPEVLGPEKY
170 180 190 200 210
250 260 270 280 290 300
pF1KE0 DKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKM
:::::::::::::::::::.:::::: : ::::::: :::.::: :::::::::::..:.
NP_001 DKSCDMWSLGVIMYILLCGFPPFYSNTGQAISPGMKRRIRLGQYGFPNPEWSEVSEDAKQ
220 230 240 250 260 270
310 320 330 340 350 360
pF1KE0 LIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSAL
::: ::::.::.:.:::.::::::: :: ::::::::.:::.:::..:..:::::::::
NP_001 LIRLLLKTDPTERLTITQFMNHPWINQSMVVPQTPLHTARVLQEDKDHWDEVKEEMTSAL
280 290 300 310 320 330
370 380 390 400
pF1KE0 ATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH
:::::::.:.::: .. ..: :: :::::
NP_001 ATMRVDYDQVKIKDLKTSNNRLLNKRRKKQAGSSSASQGCNNQ
340 350 360 370 380
>>NP_001230854 (OMIM: 602130,617111) MAP kinase-activate (382 aa)
initn: 1017 init1: 972 opt: 1762 Z-score: 721.1 bits: 142.2 E(92320): 2.2e-33
Smith-Waterman score: 1768; 70.7% identity (86.2% similar) in 369 aa overlap (21-389:12-368)
10 20 30 40 50 60
pF1KE0 MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAII
: :: :. : :. : .. : :: :.
NP_001 MDGETAEEQGGPVPP-PVAPGGPGLGGAPGGRREP----------KKYAVT
10 20 30 40
70 80 90 100 110 120
pF1KE0 DDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRI
:::....::::::.:::::. :..:: .: :::.: : ::::.::. ::.:: :::: :
NP_001 DDYQLSKQVLGLGVNGKVLECFHRRTGQKCALKLLYDSPKARQEVDHHWQASGGPHIVCI
50 60 70 80 90 100
130 140 150 160 170 180
pF1KE0 VDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSI
.:::::.. :..::::.:::..:::::::::.:::::::::::.:::..:: :::.:::
NP_001 LDVYENMHHGKRCLLIIMECMEGGELFSRIQERGDQAFTEREAAEIMRDIGTAIQFLHSH
110 120 130 140 150 160
190 200 210 220 230 240
pF1KE0 NIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKY
:::::::::::::::::. .:.::::::::::::: .:.: :::::::::::::::::::
NP_001 NIAHRDVKPENLLYTSKEKDAVLKLTDFGFAKETT-QNALQTPCYTPYYVAPEVLGPEKY
170 180 190 200 210
250 260 270 280 290 300
pF1KE0 DKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKM
:::::::::::::::::::.:::::: : ::::::: :::.::: :::::::::::..:.
NP_001 DKSCDMWSLGVIMYILLCGFPPFYSNTGQAISPGMKRRIRLGQYGFPNPEWSEVSEDAKQ
220 230 240 250 260 270
310 320 330 340 350 360
pF1KE0 LIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSAL
::: ::::.::.:.:::.::::::: :: ::::::::.:::.:::..:..:::::::::
NP_001 LIRLLLKTDPTERLTITQFMNHPWINQSMVVPQTPLHTARVLQEDKDHWDEVKEEMTSAL
280 290 300 310 320 330
370 380 390 400
pF1KE0 ATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH
:::::::.:.::: .. ..: :: :::::
NP_001 ATMRVDYDQVKIKDLKTSNNRLLNKRRKKQAGSSSASQGCNNQ
340 350 360 370 380
>>XP_024304639 (OMIM: 601684) ribosomal protein S6 kinas (643 aa)
initn: 596 init1: 206 opt: 697 Z-score: 301.3 bits: 65.3 E(92320): 5.2e-10
Smith-Waterman score: 703; 34.2% identity (66.9% similar) in 366 aa overlap (37-398:301-643)
10 20 30 40 50 60
pF1KE0 GQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVT
: :: : : . :. :: ...: :.
XP_024 SPGIPPSAGAHQLFRGFSFVATGLMEDDGKPRAPQA-PLHSVVQQLH-GKNLVFSDGYVV
280 290 300 310 320
70 80 90 100 110 120
pF1KE0 SQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPK-ARREVELHWRASQCPHIVRIVDVYE
....:.: .. . .: :. ..:.:... . .:.:. : .: :.:. . :::.
XP_024 KETIGVGSYSECKRCVHKATNMEYAVKVIDKSKRDPSEEIEILLRYGQHPNIITLKDVYD
330 340 350 360 370 380
130 140 150 160 170 180
pF1KE0 NLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHR
. :.. :.. : . ::::...: . . :.::::: ....::....:::: ...::
XP_024 D---GKHVYLVT-ELMRGGELLDKILRQ--KFFSEREASFVLHTIGKTVEYLHSQGVVHR
390 400 410 420 430 440
190 200 210 220 230 240
pF1KE0 DVKPENLLYTSKRPNA-ILKLTDFGFAKETTSHNSLT-TPCYTPYYVAPEVLGPEKYDKS
:.:: :.::... : :.. ::::::. ..:.: ::::: .:::::: . ::..
XP_024 DLKPSNILYVDESGNPECLRICDFGFAKQLRAENGLLMTPCYTANFVAPEVLKRQGYDEG
450 460 470 480 490 500
250 260 270 280 290 300
pF1KE0 CDMWSLGVIMYILLCGYPPFYSNHGLAISPG-MKTRIRMGQYEFPNPEWSEVSEEVKMLI
::.::::...: .: :: :: .: . .: . ::: :.. . . .:. ::: .: :.
XP_024 CDIWSLGILLYTMLAGYTPF--ANGPSDTPEEILTRIGSGKFTLSGGNWNTVSETAKDLV
510 520 530 540 550 560
310 320 330 340 350 360
pF1KE0 RNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALAT
..:...: ::.: . ..:::. :. :.::. : ... . :: :... ..
XP_024 SKMLHVDPHQRLTAKQVLQHPWVTQKDKLPQSQL--------SHQDLQLVKGAMAATYSA
570 580 590 600 610
370 380 390 400
pF1KE0 MRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH
. . ..: ::.. .: .:: .: : ...:
XP_024 LNSSKPTPQLKPIESS---ILAQRR--VRKLPSTTL
620 630 640
>>NP_001317370 (OMIM: 601684) ribosomal protein S6 kinas (719 aa)
initn: 623 init1: 206 opt: 697 Z-score: 300.8 bits: 65.4 E(92320): 5.6e-10
Smith-Waterman score: 703; 34.2% identity (66.9% similar) in 366 aa overlap (37-398:377-719)
10 20 30 40 50 60
pF1KE0 GQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVT
: :: : : . :. :: ...: :.
NP_001 SPGIPPSAGAHQLFRGFSFVATGLMEDDGKPRAPQA-PLHSVVQQLH-GKNLVFSDGYVV
350 360 370 380 390 400
70 80 90 100 110 120
pF1KE0 SQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPK-ARREVELHWRASQCPHIVRIVDVYE
....:.: .. . .: :. ..:.:... . .:.:. : .: :.:. . :::.
NP_001 KETIGVGSYSECKRCVHKATNMEYAVKVIDKSKRDPSEEIEILLRYGQHPNIITLKDVYD
410 420 430 440 450 460
130 140 150 160 170 180
pF1KE0 NLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHR
. :.. :.. : . ::::...: . . :.::::: ....::....:::: ...::
NP_001 D---GKHVYLVT-ELMRGGELLDKILRQ--KFFSEREASFVLHTIGKTVEYLHSQGVVHR
470 480 490 500 510
190 200 210 220 230 240
pF1KE0 DVKPENLLYTSKRPNA-ILKLTDFGFAKETTSHNSLT-TPCYTPYYVAPEVLGPEKYDKS
:.:: :.::... : :.. ::::::. ..:.: ::::: .:::::: . ::..
NP_001 DLKPSNILYVDESGNPECLRICDFGFAKQLRAENGLLMTPCYTANFVAPEVLKRQGYDEG
520 530 540 550 560 570
250 260 270 280 290 300
pF1KE0 CDMWSLGVIMYILLCGYPPFYSNHGLAISPG-MKTRIRMGQYEFPNPEWSEVSEEVKMLI
::.::::...: .: :: :: .: . .: . ::: :.. . . .:. ::: .: :.
NP_001 CDIWSLGILLYTMLAGYTPF--ANGPSDTPEEILTRIGSGKFTLSGGNWNTVSETAKDLV
580 590 600 610 620 630
310 320 330 340 350 360
pF1KE0 RNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALAT
..:...: ::.: . ..:::. :. :.::. : ... . :: :... ..
NP_001 SKMLHVDPHQRLTAKQVLQHPWVTQKDKLPQSQL--------SHQDLQLVKGAMAATYSA
640 650 660 670 680
370 380 390 400
pF1KE0 MRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH
. . ..: ::.. .: .:: .: : ...:
NP_001 LNSSKPTPQLKPIESS---ILAQRR--VRKLPSTTL
690 700 710
>>NP_002944 (OMIM: 601684) ribosomal protein S6 kinase a (735 aa)
initn: 623 init1: 206 opt: 697 Z-score: 300.7 bits: 65.4 E(92320): 5.7e-10
Smith-Waterman score: 703; 34.2% identity (66.9% similar) in 366 aa overlap (37-398:393-735)
10 20 30 40 50 60
pF1KE0 GQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVT
: :: : : . :. :: ...: :.
NP_002 SPGIPPSAGAHQLFRGFSFVATGLMEDDGKPRAPQA-PLHSVVQQLH-GKNLVFSDGYVV
370 380 390 400 410 420
70 80 90 100 110 120
pF1KE0 SQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPK-ARREVELHWRASQCPHIVRIVDVYE
....:.: .. . .: :. ..:.:... . .:.:. : .: :.:. . :::.
NP_002 KETIGVGSYSECKRCVHKATNMEYAVKVIDKSKRDPSEEIEILLRYGQHPNIITLKDVYD
430 440 450 460 470 480
130 140 150 160 170 180
pF1KE0 NLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHR
. :.. :.. : . ::::...: . . :.::::: ....::....:::: ...::
NP_002 D---GKHVYLVT-ELMRGGELLDKILRQ--KFFSEREASFVLHTIGKTVEYLHSQGVVHR
490 500 510 520 530
190 200 210 220 230 240
pF1KE0 DVKPENLLYTSKRPNA-ILKLTDFGFAKETTSHNSLT-TPCYTPYYVAPEVLGPEKYDKS
:.:: :.::... : :.. ::::::. ..:.: ::::: .:::::: . ::..
NP_002 DLKPSNILYVDESGNPECLRICDFGFAKQLRAENGLLMTPCYTANFVAPEVLKRQGYDEG
540 550 560 570 580 590
250 260 270 280 290 300
pF1KE0 CDMWSLGVIMYILLCGYPPFYSNHGLAISPG-MKTRIRMGQYEFPNPEWSEVSEEVKMLI
::.::::...: .: :: :: .: . .: . ::: :.. . . .:. ::: .: :.
NP_002 CDIWSLGILLYTMLAGYTPF--ANGPSDTPEEILTRIGSGKFTLSGGNWNTVSETAKDLV
600 610 620 630 640 650
310 320 330 340 350 360
pF1KE0 RNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALAT
..:...: ::.: . ..:::. :. :.::. : ... . :: :... ..
NP_002 SKMLHVDPHQRLTAKQVLQHPWVTQKDKLPQSQL--------SHQDLQLVKGAMAATYSA
660 670 680 690 700
370 380 390 400
pF1KE0 MRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH
. . ..: ::.. .: .:: .: : ...:
NP_002 LNSSKPTPQLKPIESS---ILAQRR--VRKLPSTTL
710 720 730
400 residues in 1 query sequences
64369986 residues in 92320 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Thu Oct 24 21:37:19 2019 done: Thu Oct 24 21:37:19 2019
Total Scan time: 4.760 Total Display time: 0.050
Function used was FASTA [36.3.4 Apr, 2011]