Result of FASTA (omim) for
pFN21AE1608
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE1608, 114 aa
1>>>pF1KE1608 114 - 114 aa - 114 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.3091+/-0.000286; mu= 11.2160+/- 0.018
mean_var=75.1787+/-14.923, 0's: 0 Z-trim(118.9): 61 B-trim: 902 in 1/58
Lambda= 0.147920
statistics sampled from 32362 (32427) to 32362 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.761), E-opt: 0.2 (0.38), width: 16
Scan time: 4.640
The best scores are: opt bits E(85289)
NP_002956 (OMIM: 123886) protein S100-A9 [Homo sap ( 114) 775 173.5 6.4e-44
NP_005612 (OMIM: 603112) protein S100-A12 [Homo sa ( 92) 274 66.5 8.3e-12
XP_016883913 (OMIM: 176990) PREDICTED: protein S10 ( 92) 230 57.2 5.6e-09
NP_006263 (OMIM: 176990) protein S100-B [Homo sapi ( 92) 230 57.2 5.6e-09
NP_005971 (OMIM: 600614) protein S100-P [Homo sapi ( 95) 214 53.7 6.1e-08
NP_006262 (OMIM: 176940) protein S100-A1 [Homo sap ( 94) 205 51.8 2.3e-07
XP_016864662 (OMIM: 610103) PREDICTED: protein S10 ( 99) 200 50.8 5e-07
XP_016864661 (OMIM: 610103) PREDICTED: protein S10 ( 99) 200 50.8 5e-07
XP_011541547 (OMIM: 610103) PREDICTED: protein S10 ( 99) 200 50.8 5e-07
XP_011541541 (OMIM: 610103) PREDICTED: protein S10 ( 99) 200 50.8 5e-07
XP_011541543 (OMIM: 610103) PREDICTED: protein S10 ( 99) 200 50.8 5e-07
XP_011541546 (OMIM: 610103) PREDICTED: protein S10 ( 99) 200 50.8 5e-07
XP_016864660 (OMIM: 610103) PREDICTED: protein S10 ( 99) 200 50.8 5e-07
XP_011541542 (OMIM: 610103) PREDICTED: protein S10 ( 99) 200 50.8 5e-07
NP_570128 (OMIM: 610103) protein S100-Z [Homo sapi ( 99) 200 50.8 5e-07
NP_062427 (OMIM: 114210) protein S100-A4 [Homo sap ( 101) 197 50.1 7.9e-07
NP_002952 (OMIM: 114210) protein S100-A4 [Homo sap ( 101) 197 50.1 7.9e-07
NP_005611 (OMIM: 603114) protein S100-A11 [Homo sa ( 105) 197 50.1 8.2e-07
NP_005969 (OMIM: 176993) protein S100-A2 [Homo sap ( 97) 195 49.7 1e-06
NP_002007 (OMIM: 135940,146700,605803) filaggrin [ (4061) 211 54.3 1.8e-06
XP_011507833 (OMIM: 616284) PREDICTED: filaggrin-2 (2239) 199 51.5 6.7e-06
NP_001014364 (OMIM: 616284) filaggrin-2 [Homo sapi (2391) 199 51.5 7.1e-06
NP_055439 (OMIM: 114110) protein S100-A6 [Homo sap ( 90) 176 45.6 1.6e-05
XP_016857522 (OMIM: 114110) PREDICTED: protein S10 ( 90) 176 45.6 1.6e-05
XP_011508164 (OMIM: 601989) PREDICTED: protein S10 ( 98) 175 45.4 2e-05
XP_005245491 (OMIM: 601989) PREDICTED: protein S10 ( 98) 175 45.4 2e-05
NP_005970 (OMIM: 601989) protein S100-A13 [Homo sa ( 98) 175 45.4 2e-05
XP_016857525 (OMIM: 601989) PREDICTED: protein S10 ( 98) 175 45.4 2e-05
XP_011508166 (OMIM: 601989) PREDICTED: protein S10 ( 98) 175 45.4 2e-05
XP_011508165 (OMIM: 601989) PREDICTED: protein S10 ( 98) 175 45.4 2e-05
NP_001019381 (OMIM: 601989) protein S100-A13 [Homo ( 98) 175 45.4 2e-05
XP_016857523 (OMIM: 601989) PREDICTED: protein S10 ( 98) 175 45.4 2e-05
NP_001019384 (OMIM: 601989) protein S100-A13 [Homo ( 98) 175 45.4 2e-05
NP_001019382 (OMIM: 601989) protein S100-A13 [Homo ( 98) 175 45.4 2e-05
XP_016857524 (OMIM: 601989) PREDICTED: protein S10 ( 98) 175 45.4 2e-05
NP_001019383 (OMIM: 601989) protein S100-A13 [Homo ( 98) 175 45.4 2e-05
NP_002953 (OMIM: 176991) protein S100-A5 [Homo sap ( 92) 174 45.2 2.2e-05
XP_016857521 (OMIM: 176991) PREDICTED: protein S10 ( 92) 174 45.2 2.2e-05
XP_016857520 (OMIM: 176991) PREDICTED: protein S10 ( 92) 174 45.2 2.2e-05
XP_011508162 (OMIM: 176991) PREDICTED: protein S10 ( 104) 174 45.2 2.4e-05
XP_016857519 (OMIM: 176991) PREDICTED: protein S10 ( 110) 174 45.3 2.5e-05
XP_016857518 (OMIM: 176991) PREDICTED: protein S10 ( 133) 174 45.3 3e-05
NP_001009931 (OMIM: 616293) hornerin [Homo sapiens (2850) 190 49.7 3.1e-05
NP_001306130 (OMIM: 123885) protein S100-A8 isofor ( 93) 169 44.1 4.7e-05
NP_002955 (OMIM: 123885) protein S100-A8 isoform d ( 93) 169 44.1 4.7e-05
NP_001306127 (OMIM: 123885) protein S100-A8 isofor ( 101) 169 44.2 5e-05
NP_001306126 (OMIM: 123885) protein S100-A8 isofor ( 116) 169 44.2 5.6e-05
NP_001306125 (OMIM: 123885) protein S100-A8 isofor ( 117) 169 44.2 5.6e-05
NP_002957 (OMIM: 114085) protein S100-A10 [Homo sa ( 97) 161 42.4 0.00016
NP_004048 (OMIM: 302020) protein S100-G [Homo sapi ( 79) 157 41.5 0.00024
>>NP_002956 (OMIM: 123886) protein S100-A9 [Homo sapiens (114 aa)
initn: 775 init1: 775 opt: 775 Z-score: 909.4 bits: 173.5 E(85289): 6.4e-44
Smith-Waterman score: 775; 100.0% identity (100.0% similar) in 114 aa overlap (1-114:1-114)
10 20 30 40 50 60
pF1KE1 MTCKMSQLERNIETIINTFHQYSVKLGHPDTLNQGEFKELVRKDLQNFLKKENKNEKVIE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 MTCKMSQLERNIETIINTFHQYSVKLGHPDTLNQGEFKELVRKDLQNFLKKENKNEKVIE
10 20 30 40 50 60
70 80 90 100 110
pF1KE1 HIMEDLDTNADKQLSFEEFIMLMARLTWASHEKMHEGDEGPGHHHKPGLGEGTP
::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 HIMEDLDTNADKQLSFEEFIMLMARLTWASHEKMHEGDEGPGHHHKPGLGEGTP
70 80 90 100 110
>>NP_005612 (OMIM: 603112) protein S100-A12 [Homo sapien (92 aa)
initn: 252 init1: 164 opt: 274 Z-score: 332.9 bits: 66.5 E(85289): 8.3e-12
Smith-Waterman score: 274; 46.7% identity (79.3% similar) in 92 aa overlap (5-96:1-91)
10 20 30 40 50 60
pF1KE1 MTCKMSQLERNIETIINTFHQYSVKLGHPDTLNQGEFKELVRKDLQNFLKKENKNEKVIE
:..::...: :.: ::::::. :: :::..::.:.:. :.: : .:. :.. ::.
NP_005 MTKLEEHLEGIVNIFHQYSVRKGHFDTLSKGELKQLLTKELANTIKN-IKDKAVID
10 20 30 40 50
70 80 90 100 110
pF1KE1 HIMEDLDTNADKQLSFEEFIMLMARLTWASHEKMHEGDEGPGHHHKPGLGEGTP
.:.. ::.: :.:..:.::: :.: :.: . :.
NP_005 EIFQGLDANQDEQVDFQEFISLVAIALKAAHYHTHKE
60 70 80 90
>>XP_016883913 (OMIM: 176990) PREDICTED: protein S100-B (92 aa)
initn: 135 init1: 135 opt: 230 Z-score: 282.2 bits: 57.2 E(85289): 5.6e-09
Smith-Waterman score: 230; 39.8% identity (79.5% similar) in 88 aa overlap (5-92:1-87)
10 20 30 40 50 60
pF1KE1 MTCKMSQLERNIETIINTFHQYSVKLGHPDTLNQGEFKELVRKDLQNFLKKENKNEKVIE
::.::. . ..:..::::: . : :...:.:::. ..:..::. : :...:..
XP_016 MSELEKAMVALIDVFHQYSGREGDKHKLKKSELKELINNELSHFLE-EIKEQEVVD
10 20 30 40 50
70 80 90 100 110
pF1KE1 HIMEDLDTNADKQLSFEEFIMLMARLTWASHEKMHEGDEGPGHHHKPGLGEGTP
..:: ::...: . .:.::. ..: .: : ::
XP_016 KVMETLDNDGDGECDFQEFMAFVAMVTTACHEFFEHE
60 70 80 90
>>NP_006263 (OMIM: 176990) protein S100-B [Homo sapiens] (92 aa)
initn: 135 init1: 135 opt: 230 Z-score: 282.2 bits: 57.2 E(85289): 5.6e-09
Smith-Waterman score: 230; 39.8% identity (79.5% similar) in 88 aa overlap (5-92:1-87)
10 20 30 40 50 60
pF1KE1 MTCKMSQLERNIETIINTFHQYSVKLGHPDTLNQGEFKELVRKDLQNFLKKENKNEKVIE
::.::. . ..:..::::: . : :...:.:::. ..:..::. : :...:..
NP_006 MSELEKAMVALIDVFHQYSGREGDKHKLKKSELKELINNELSHFLE-EIKEQEVVD
10 20 30 40 50
70 80 90 100 110
pF1KE1 HIMEDLDTNADKQLSFEEFIMLMARLTWASHEKMHEGDEGPGHHHKPGLGEGTP
..:: ::...: . .:.::. ..: .: : ::
NP_006 KVMETLDNDGDGECDFQEFMAFVAMVTTACHEFFEHE
60 70 80 90
>>NP_005971 (OMIM: 600614) protein S100-P [Homo sapiens] (95 aa)
initn: 183 init1: 104 opt: 214 Z-score: 263.5 bits: 53.7 E(85289): 6.1e-08
Smith-Waterman score: 214; 38.6% identity (79.5% similar) in 88 aa overlap (5-92:1-87)
10 20 30 40 50 60
pF1KE1 MTCKMSQLERNIETIINTFHQYSVKLGHPDTLNQGEFKELVRKDLQNFLKKENKNEKVIE
:..:: . ::..: .:: . : .::..::.: :..:.: .::.. .:.. ...
NP_005 MTELETAMGMIIDVFSRYSGSEGSTQTLTKGELKVLMEKELPGFLQS-GKDKDAVD
10 20 30 40 50
70 80 90 100 110
pF1KE1 HIMEDLDTNADKQLSFEEFIMLMARLTWASHEKMHEGDEGPGHHHKPGLGEGTP
....:::.:.: :..: :::...: .: : :.
NP_005 KLLKDLDANGDAQVDFSEFIVFVAAITSACHKYFEKAGLK
60 70 80 90
>>NP_006262 (OMIM: 176940) protein S100-A1 [Homo sapiens (94 aa)
initn: 114 init1: 114 opt: 205 Z-score: 253.2 bits: 51.8 E(85289): 2.3e-07
Smith-Waterman score: 205; 39.3% identity (76.2% similar) in 84 aa overlap (6-89:3-85)
10 20 30 40 50 60
pF1KE1 MTCKMSQLERNIETIINTFHQYSVKLGHPDTLNQGEFKELVRKDLQNFLKKENKNEKVIE
:.:: .::.::.:: .: : : :.. :.:::.. .:..:: . :. ...
NP_006 MGSELETAMETLINVFHAHSGKEGDKYKLSKKELKELLQTELSGFLDAQ-KDVDAVD
10 20 30 40 50
70 80 90 100 110
pF1KE1 HIMEDLDTNADKQLSFEEFIMLMARLTWASHEKMHEGDEGPGHHHKPGLGEGTP
..:..:: :.: ...:.:...:.: :: :
NP_006 KVMKELDENGDGEVDFQEYVVLVAALTVACNNFFWENS
60 70 80 90
>>XP_016864662 (OMIM: 610103) PREDICTED: protein S100-Z (99 aa)
initn: 179 init1: 107 opt: 200 Z-score: 247.1 bits: 50.8 E(85289): 5e-07
Smith-Waterman score: 200; 36.8% identity (78.2% similar) in 87 aa overlap (6-92:3-88)
10 20 30 40 50 60
pF1KE1 MTCKMSQLERNIETIINTFHQYSVKLGHPDTLNQGEFKELVRKDLQNFLKKENKNEKVIE
.::: ..:.: ::.:: : . :..::.: :....: .::. . :. ....
XP_016 MPTQLEMAMDTMIRIFHRYSGKERKRFKLSKGELKLLLQRELTEFLSCQ-KETQLVD
10 20 30 40 50
70 80 90 100 110
pF1KE1 HIMEDLDTNADKQLSFEEFIMLMARLTWASHEKMHEGDEGPGHHHKPGLGEGTP
.:..:::.: :....:.::....: :: : ..
XP_016 KIVQDLDANKDNEVDFNEFVVMVAALTVACNDYFVEQLKKKGK
60 70 80 90
>>XP_016864661 (OMIM: 610103) PREDICTED: protein S100-Z (99 aa)
initn: 179 init1: 107 opt: 200 Z-score: 247.1 bits: 50.8 E(85289): 5e-07
Smith-Waterman score: 200; 36.8% identity (78.2% similar) in 87 aa overlap (6-92:3-88)
10 20 30 40 50 60
pF1KE1 MTCKMSQLERNIETIINTFHQYSVKLGHPDTLNQGEFKELVRKDLQNFLKKENKNEKVIE
.::: ..:.: ::.:: : . :..::.: :....: .::. . :. ....
XP_016 MPTQLEMAMDTMIRIFHRYSGKERKRFKLSKGELKLLLQRELTEFLSCQ-KETQLVD
10 20 30 40 50
70 80 90 100 110
pF1KE1 HIMEDLDTNADKQLSFEEFIMLMARLTWASHEKMHEGDEGPGHHHKPGLGEGTP
.:..:::.: :....:.::....: :: : ..
XP_016 KIVQDLDANKDNEVDFNEFVVMVAALTVACNDYFVEQLKKKGK
60 70 80 90
>>XP_011541547 (OMIM: 610103) PREDICTED: protein S100-Z (99 aa)
initn: 179 init1: 107 opt: 200 Z-score: 247.1 bits: 50.8 E(85289): 5e-07
Smith-Waterman score: 200; 36.8% identity (78.2% similar) in 87 aa overlap (6-92:3-88)
10 20 30 40 50 60
pF1KE1 MTCKMSQLERNIETIINTFHQYSVKLGHPDTLNQGEFKELVRKDLQNFLKKENKNEKVIE
.::: ..:.: ::.:: : . :..::.: :....: .::. . :. ....
XP_011 MPTQLEMAMDTMIRIFHRYSGKERKRFKLSKGELKLLLQRELTEFLSCQ-KETQLVD
10 20 30 40 50
70 80 90 100 110
pF1KE1 HIMEDLDTNADKQLSFEEFIMLMARLTWASHEKMHEGDEGPGHHHKPGLGEGTP
.:..:::.: :....:.::....: :: : ..
XP_011 KIVQDLDANKDNEVDFNEFVVMVAALTVACNDYFVEQLKKKGK
60 70 80 90
>>XP_011541541 (OMIM: 610103) PREDICTED: protein S100-Z (99 aa)
initn: 179 init1: 107 opt: 200 Z-score: 247.1 bits: 50.8 E(85289): 5e-07
Smith-Waterman score: 200; 36.8% identity (78.2% similar) in 87 aa overlap (6-92:3-88)
10 20 30 40 50 60
pF1KE1 MTCKMSQLERNIETIINTFHQYSVKLGHPDTLNQGEFKELVRKDLQNFLKKENKNEKVIE
.::: ..:.: ::.:: : . :..::.: :....: .::. . :. ....
XP_011 MPTQLEMAMDTMIRIFHRYSGKERKRFKLSKGELKLLLQRELTEFLSCQ-KETQLVD
10 20 30 40 50
70 80 90 100 110
pF1KE1 HIMEDLDTNADKQLSFEEFIMLMARLTWASHEKMHEGDEGPGHHHKPGLGEGTP
.:..:::.: :....:.::....: :: : ..
XP_011 KIVQDLDANKDNEVDFNEFVVMVAALTVACNDYFVEQLKKKGK
60 70 80 90
114 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 18:54:39 2016 done: Sun Nov 6 18:54:40 2016
Total Scan time: 4.640 Total Display time: -0.020
Function used was FASTA [36.3.4 Apr, 2011]