Result of FASTA (omim) for
pFN21AE3023
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE3023, 138 aa
1>>>pF1KE3023 138 - 138 aa - 138 aa
Library: /omim/omim.rfq.tfa
65951994 residues in 93482 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.0008+/-0.000331; mu= 13.1890+/- 0.020
mean_var=67.1228+/-13.769, 0's: 0 Z-trim(115.5): 33 B-trim: 199 in 1/49
Lambda= 0.156545
statistics sampled from 27183 (27210) to 27183 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.668), E-opt: 0.2 (0.291), width: 16
Scan time: 2.630
The best scores are: opt bits E(93482)
NP_000540 (OMIM: 188540,275100) thyrotropin subuni ( 138) 977 228.9 2.2e-60
XP_011540367 (OMIM: 188540,275100) thyrotropin sub ( 138) 977 228.9 2.2e-60
NP_001264920 (OMIM: 188540,275100) thyrotropin sub ( 93) 603 144.3 4.2e-35
NP_000501 (OMIM: 136530,229070) follitropin subuni ( 129) 378 93.6 1.1e-19
NP_001018090 (OMIM: 136530,229070) follitropin sub ( 129) 378 93.6 1.1e-19
NP_000885 (OMIM: 152780,228300) lutropin subunit b ( 141) 355 88.5 4.2e-18
XP_011525277 (OMIM: 152780,228300) lutropin subuni ( 157) 355 88.5 4.6e-18
NP_203695 (OMIM: 608823) choriogonadotropin subuni ( 155) 337 84.4 7.7e-17
NP_203696 (OMIM: 608824) choriogonadotropin subuni ( 163) 337 84.4 8e-17
NP_000728 (OMIM: 118860) choriogonadotropin subuni ( 165) 337 84.5 8e-17
NP_149439 (OMIM: 608827) chorionic gonadotropin, b ( 165) 337 84.5 8e-17
NP_149032 (OMIM: 608825) chorionic gonadotropin, b ( 165) 337 84.5 8e-17
XP_005258536 (OMIM: 608824) choriogonadotropin sub ( 181) 337 84.5 8.6e-17
NP_149133 (OMIM: 608826) choriogonadotropin subuni ( 165) 336 84.2 9.4e-17
XP_024307552 (OMIM: 608826) choriogonadotropin sub ( 165) 336 84.2 9.4e-17
NP_001305994 (OMIM: 608824) choriogonadotropin sub ( 151) 333 83.5 1.4e-16
NP_660154 (OMIM: 609652) glycoprotein hormone beta ( 130) 221 58.2 5.1e-09
>>NP_000540 (OMIM: 188540,275100) thyrotropin subunit be (138 aa)
initn: 977 init1: 977 opt: 977 Z-score: 1206.0 bits: 228.9 E(93482): 2.2e-60
Smith-Waterman score: 977; 99.3% identity (100.0% similar) in 138 aa overlap (1-138:1-138)
10 20 30 40 50 60
pF1KE3 MTALFLMSMLFGLACGQAMSFCIPTEYTMHIERRECAYCLTINTTICAGYCMTRDINGKL
:::::::::::::.::::::::::::::::::::::::::::::::::::::::::::::
NP_000 MTALFLMSMLFGLTCGQAMSFCIPTEYTMHIERRECAYCLTINTTICAGYCMTRDINGKL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 FLPKYALSQDVCTYRDFIYRTVEIPGCPLHVAPYFSYPVALSCKCGKCNTDYSDCIHEAI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 FLPKYALSQDVCTYRDFIYRTVEIPGCPLHVAPYFSYPVALSCKCGKCNTDYSDCIHEAI
70 80 90 100 110 120
130
pF1KE3 KTNYCTKPQKSYLVGFSV
::::::::::::::::::
NP_000 KTNYCTKPQKSYLVGFSV
130
>>XP_011540367 (OMIM: 188540,275100) thyrotropin subunit (138 aa)
initn: 977 init1: 977 opt: 977 Z-score: 1206.0 bits: 228.9 E(93482): 2.2e-60
Smith-Waterman score: 977; 99.3% identity (100.0% similar) in 138 aa overlap (1-138:1-138)
10 20 30 40 50 60
pF1KE3 MTALFLMSMLFGLACGQAMSFCIPTEYTMHIERRECAYCLTINTTICAGYCMTRDINGKL
:::::::::::::.::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MTALFLMSMLFGLTCGQAMSFCIPTEYTMHIERRECAYCLTINTTICAGYCMTRDINGKL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 FLPKYALSQDVCTYRDFIYRTVEIPGCPLHVAPYFSYPVALSCKCGKCNTDYSDCIHEAI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FLPKYALSQDVCTYRDFIYRTVEIPGCPLHVAPYFSYPVALSCKCGKCNTDYSDCIHEAI
70 80 90 100 110 120
130
pF1KE3 KTNYCTKPQKSYLVGFSV
::::::::::::::::::
XP_011 KTNYCTKPQKSYLVGFSV
130
>>NP_001264920 (OMIM: 188540,275100) thyrotropin subunit (93 aa)
initn: 603 init1: 603 opt: 603 Z-score: 751.9 bits: 144.3 E(93482): 4.2e-35
Smith-Waterman score: 603; 98.8% identity (100.0% similar) in 85 aa overlap (54-138:9-93)
30 40 50 60 70 80
pF1KE3 PTEYTMHIERRECAYCLTINTTICAGYCMTRDINGKLFLPKYALSQDVCTYRDFIYRTVE
.:::::::::::::::::::::::::::::
NP_001 MLSFLFFPQDINGKLFLPKYALSQDVCTYRDFIYRTVE
10 20 30
90 100 110 120 130
pF1KE3 IPGCPLHVAPYFSYPVALSCKCGKCNTDYSDCIHEAIKTNYCTKPQKSYLVGFSV
:::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IPGCPLHVAPYFSYPVALSCKCGKCNTDYSDCIHEAIKTNYCTKPQKSYLVGFSV
40 50 60 70 80 90
>>NP_000501 (OMIM: 136530,229070) follitropin subunit be (129 aa)
initn: 402 init1: 224 opt: 378 Z-score: 475.2 bits: 93.6 E(93482): 1.1e-19
Smith-Waterman score: 378; 40.2% identity (72.1% similar) in 122 aa overlap (7-126:4-123)
10 20 30 40 50
pF1KE3 MTALFLMSMLFGLACGQAM--SFCIPTEYTMHIERRECAYCLTINTTICAGYCMTRDING
....: . : .:. . : :. :. ::..:: .:..:::: :::::.:::.
NP_000 MKTLQFFFLFCCWKAICCNSCELTNITIAIEKEECRFCISINTTWCAGYCYTRDLVY
10 20 30 40 50
60 70 80 90 100 110
pF1KE3 KLFLPKYALSQDVCTYRDFIYRTVEIPGCPLHVAPYFSYPVALSCKCGKCNTDYSDCIHE
: : : .::.....:.::..::: :. ..:::: .:.::::..: .:: .
NP_000 KD--PARPKIQKTCTFKELVYETVRVPGCAHHADSLYTYPVATQCHCGKCDSDSTDCTVR
60 70 80 90 100 110
120 130
pF1KE3 AIKTNYCTKPQKSYLVGFSV
.. .::.
NP_000 GLGPSYCSFGEMKE
120
>>NP_001018090 (OMIM: 136530,229070) follitropin subunit (129 aa)
initn: 402 init1: 224 opt: 378 Z-score: 475.2 bits: 93.6 E(93482): 1.1e-19
Smith-Waterman score: 378; 40.2% identity (72.1% similar) in 122 aa overlap (7-126:4-123)
10 20 30 40 50
pF1KE3 MTALFLMSMLFGLACGQAM--SFCIPTEYTMHIERRECAYCLTINTTICAGYCMTRDING
....: . : .:. . : :. :. ::..:: .:..:::: :::::.:::.
NP_001 MKTLQFFFLFCCWKAICCNSCELTNITIAIEKEECRFCISINTTWCAGYCYTRDLVY
10 20 30 40 50
60 70 80 90 100 110
pF1KE3 KLFLPKYALSQDVCTYRDFIYRTVEIPGCPLHVAPYFSYPVALSCKCGKCNTDYSDCIHE
: : : .::.....:.::..::: :. ..:::: .:.::::..: .:: .
NP_001 KD--PARPKIQKTCTFKELVYETVRVPGCAHHADSLYTYPVATQCHCGKCDSDSTDCTVR
60 70 80 90 100 110
120 130
pF1KE3 AIKTNYCTKPQKSYLVGFSV
.. .::.
NP_001 GLGPSYCSFGEMKE
120
>>NP_000885 (OMIM: 152780,228300) lutropin subunit beta (141 aa)
initn: 369 init1: 225 opt: 355 Z-score: 446.6 bits: 88.5 E(93482): 4.2e-18
Smith-Waterman score: 355; 41.7% identity (61.4% similar) in 132 aa overlap (4-134:10-139)
10 20 30 40 50
pF1KE3 MTALFLMSMLFGLACGQAMS-FCIPTEYTMHIERRECAYCLTINTTICAGYCMT
:.:.:: . : . . .: : . . .:.. : :.:.::::::::: :
NP_000 MEMLQGLLLLLLLSMGGAWASREPLRPWCHPINAILAVEKEGCPVCITVNTTICAGYCPT
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE3 RDINGKLFLPKYALSQDVCTYRDFIYRTVEIPGCPLHVAPYFSYPVALSCKCGKCNTDYS
. :: : : :::::: ......:::: : : :.::::::.:: : . :
NP_000 MMRVLQAVLP--PLPQVVCTYRDVRFESIRLPGCPRGVDPVVSFPVALSCRCGPCRRSTS
70 80 90 100 110
120 130
pF1KE3 DCIHEAIKTNYCTKPQKSYLVGFSV
:: . : .:: : :.
NP_000 DCGGPKDHPLTCDHPQLSGLLFL
120 130 140
>>XP_011525277 (OMIM: 152780,228300) lutropin subunit be (157 aa)
initn: 356 init1: 225 opt: 355 Z-score: 446.0 bits: 88.5 E(93482): 4.6e-18
Smith-Waterman score: 355; 41.7% identity (61.4% similar) in 132 aa overlap (4-134:26-155)
10 20 30
pF1KE3 MTALFLMSMLFGLACGQAMS-FCIPTEYTMHIERRECA
:.:.:: . : . . .: : . . .:.. :
XP_011 MGRPGLGAAVSDLGEAVSLSQGLLLLLLLSMGGAWASREPLRPWCHPINAILAVEKEGCP
10 20 30 40 50 60
40 50 60 70 80 90
pF1KE3 YCLTINTTICAGYCMTRDINGKLFLPKYALSQDVCTYRDFIYRTVEIPGCPLHVAPYFSY
:.:.::::::::: : . :: : : :::::: ......:::: : : :.
XP_011 VCITVNTTICAGYCPTMMRVLQAVLP--PLPQVVCTYRDVRFESIRLPGCPRGVDPVVSF
70 80 90 100 110
100 110 120 130
pF1KE3 PVALSCKCGKCNTDYSDCIHEAIKTNYCTKPQKSYLVGFSV
::::::.:: : . ::: . : .:: : :.
XP_011 PVALSCRCGPCRRSTSDCGGPKDHPLTCDHPQLSGLLFL
120 130 140 150
>>NP_203695 (OMIM: 608823) choriogonadotropin subunit be (155 aa)
initn: 321 init1: 197 opt: 337 Z-score: 424.1 bits: 84.4 E(93482): 7.7e-17
Smith-Waterman score: 337; 41.9% identity (62.0% similar) in 129 aa overlap (4-129:8-132)
10 20 30 40 50
pF1KE3 MTALFLMSMLFGLACGQAMS-FCIPTEYTMHIERRECAYCLTINTTICAGYC--MT
:.:.:: : . . : : . :. .:.. : :.:.::::::::: ::
NP_203 MSKRLLLLLLLSMGGTWASKEPLRPRCRPINATLAVEKEGCPVCITVNTTICAGYCPTMT
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE3 RDINGKLFLPKYALSQDVCTYRDFIYRTVEIPGCPLHVAPYFSYPVALSCKCGKCNTDYS
: ..: :: :: : ::.::: ......:::: : : :: :::::.:. : . .
NP_203 RVLQG--VLP--ALPQVVCNYRDVRFESIRLPGCPRGVNPVVSYAVALSCQCALCRRSTT
70 80 90 100 110
120 130
pF1KE3 DCIHEAIKTNYCTKPQKSYLVGFSV
:: . : :.
NP_203 DCGGPKDHPLTCDDPRFQDSSSSKAPPPSLPSPSRLPGP
120 130 140 150
>>NP_203696 (OMIM: 608824) choriogonadotropin subunit be (163 aa)
initn: 321 init1: 197 opt: 337 Z-score: 423.8 bits: 84.4 E(93482): 8e-17
Smith-Waterman score: 337; 41.9% identity (62.0% similar) in 129 aa overlap (4-129:8-132)
10 20 30 40 50
pF1KE3 MTALFLMSMLFGLACGQAMS-FCIPTEYTMHIERRECAYCLTINTTICAGYC--MT
:.:.:: : . . : : . :. .:.. : :.:.::::::::: ::
NP_203 MSKGLLLLLLLSMGGTWASKEPLRPRCRPINATLAVEKEGCPVCITVNTTICAGYCPTMT
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE3 RDINGKLFLPKYALSQDVCTYRDFIYRTVEIPGCPLHVAPYFSYPVALSCKCGKCNTDYS
: ..: :: :: : ::.::: ......:::: : : :: :::::.:. : . .
NP_203 RVLQG--VLP--ALPQVVCNYRDVRFESIRLPGCPRGVNPVVSYAVALSCQCALCRRSTT
70 80 90 100 110
120 130
pF1KE3 DCIHEAIKTNYCTKPQKSYLVGFSV
:: . : :.
NP_203 DCGGPKDHPLTCDDPRFQASSSSKAPPPSLPSPSRLPGPSDTPILPQ
120 130 140 150 160
>>NP_000728 (OMIM: 118860) choriogonadotropin subunit be (165 aa)
initn: 321 init1: 197 opt: 337 Z-score: 423.7 bits: 84.5 E(93482): 8e-17
Smith-Waterman score: 337; 41.9% identity (62.0% similar) in 129 aa overlap (4-129:10-134)
10 20 30 40 50
pF1KE3 MTALFLMSMLFGLACGQAMS-FCIPTEYTMHIERRECAYCLTINTTICAGYC--
:.:.:: : . . : : . :. .:.. : :.:.:::::::::
NP_000 MEMFQGLLLLLLLSMGGTWASKEPLRPRCRPINATLAVEKEGCPVCITVNTTICAGYCPT
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE3 MTRDINGKLFLPKYALSQDVCTYRDFIYRTVEIPGCPLHVAPYFSYPVALSCKCGKCNTD
::: ..: :: :: : ::.::: ......:::: : : :: :::::.:. : .
NP_000 MTRVLQG--VLP--ALPQVVCNYRDVRFESIRLPGCPRGVNPVVSYAVALSCQCALCRRS
70 80 90 100 110
120 130
pF1KE3 YSDCIHEAIKTNYCTKPQKSYLVGFSV
.:: . : :.
NP_000 TTDCGGPKDHPLTCDDPRFQDSSSSKAPPPSLPSPSRLPGPSDTPILPQ
120 130 140 150 160
138 residues in 1 query sequences
65951994 residues in 93482 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Thu Jun 20 10:38:24 2019 done: Thu Jun 20 10:38:24 2019
Total Scan time: 2.630 Total Display time: 0.030
Function used was FASTA [36.3.4 Apr, 2011]