Result of FASTA (omim) for
pFN21AE2560
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE2560, 209 aa
1>>>pF1KE2560 209 - 209 aa - 209 aa
Library: /omim/omim.rfq.tfa
64092750 residues in 91774 sequences
Statistics: Expectation_n fit: rho(ln(x))= 4.8495+/-0.00028; mu= 16.2396+/- 0.018
mean_var=56.2093+/-11.197, 0's: 0 Z-trim(117.8): 24 B-trim: 1393 in 1/51
Lambda= 0.171069
statistics sampled from 31279 (31298) to 31279 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.727), E-opt: 0.2 (0.341), width: 16
Scan time: 4.210
The best scores are: opt bits E(91774)
NP_003174 (OMIM: 603639,614328) disintegrin and me ( 824) 1365 344.6 2.9e-94
XP_011508677 (OMIM: 603639,614328) disintegrin and ( 793) 1135 287.8 3.4e-77
NP_001307499 (OMIM: 602192,615537,615590) disinteg ( 717) 166 48.7 3.1e-05
NP_001101 (OMIM: 602192,615537,615590) disintegrin ( 748) 166 48.7 3.2e-05
>>NP_003174 (OMIM: 603639,614328) disintegrin and metall (824 aa)
initn: 1365 init1: 1365 opt: 1365 Z-score: 1814.0 bits: 344.6 E(91774): 2.9e-94
Smith-Waterman score: 1365; 100.0% identity (100.0% similar) in 206 aa overlap (1-206:1-206)
10 20 30 40 50 60
pF1KE2 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 QTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 QTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVV
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 GEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 GEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQS
130 140 150 160 170 180
190 200
pF1KE2 PKVCGYLKVDNEELLPKGLVDREPPEGKT
::::::::::::::::::::::::::
NP_003 PKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMG
190 200 210 220 230 240
>>XP_011508677 (OMIM: 603639,614328) disintegrin and met (793 aa)
initn: 1135 init1: 1135 opt: 1135 Z-score: 1507.4 bits: 287.8 E(91774): 3.4e-77
Smith-Waterman score: 1135; 98.9% identity (100.0% similar) in 175 aa overlap (32-206:1-175)
10 20 30 40 50 60
pF1KE2 RQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQ
..::::::::::::::::::::::::::::
XP_011 MKKLDSLLSDYDILSLSNIQQHSVRKRDLQ
10 20 30
70 80 90 100 110 120
pF1KE2 TSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVG
40 50 60 70 80 90
130 140 150 160 170 180
pF1KE2 EPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSP
100 110 120 130 140 150
190 200
pF1KE2 KVCGYLKVDNEELLPKGLVDREPPEGKT
:::::::::::::::::::::::::
XP_011 KVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGR
160 170 180 190 200 210
>>NP_001307499 (OMIM: 602192,615537,615590) disintegrin (717 aa)
initn: 162 init1: 87 opt: 166 Z-score: 215.6 bits: 48.7 E(91774): 3.1e-05
Smith-Waterman score: 166; 27.8% identity (56.8% similar) in 162 aa overlap (25-182:16-170)
10 20 30 40 50 60
pF1KE2 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDL
:.: : . :.. . :. :: . . :. ..:
NP_001 MVLLRVLILLLSWAAGMGG-QYGNPLNKYIRHYEGLSYNVDSLHQKHQRAK
10 20 30 40 50
70 80 90 100 110
pF1KE2 QTSTHVETLLT--FSALKRHFKLYLTSSTERFSQNFKVVVVDGKNES-EYTVKWQDFFTG
.. .: . .: : : :::.: . .: ::..:: :. .:. .: .. ..::
NP_001 RAVSHEDQFLRLDFHAHGRHFNLRMKRDTSLFSDEFK---VETSNKVLDYDTS--HIYTG
60 70 80 90 100
120 130 140 150 160 170
pF1KE2 HVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVND-TKDKRMLVYKSEDIKNVS
:. :: : . . : :.: :. . .:: :...: : . ..:. .:: :
NP_001 HIYGEEGSFSHGSVIDGRFEGFIQTRGGTFYVEPAERYIKDRTLPFHSVIYHEDDI-NYP
110 120 130 140 150 160
180 190 200
pF1KE2 RLQSPKVCGYLKVDNEELLPKGLVDREPPEGKT
. .:.
NP_001 HKYGPQGGCADHSVFERMRKYQMTGVEEVTQIPQEEHAANGPELLRKKRTTSAEKNTCQL
170 180 190 200 210 220
>>NP_001101 (OMIM: 602192,615537,615590) disintegrin and (748 aa)
initn: 162 init1: 87 opt: 166 Z-score: 215.3 bits: 48.7 E(91774): 3.2e-05
Smith-Waterman score: 166; 27.8% identity (56.8% similar) in 162 aa overlap (25-182:16-170)
10 20 30 40 50 60
pF1KE2 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDL
:.: : . :.. . :. :: . . :. ..:
NP_001 MVLLRVLILLLSWAAGMGG-QYGNPLNKYIRHYEGLSYNVDSLHQKHQRAK
10 20 30 40 50
70 80 90 100 110
pF1KE2 QTSTHVETLLT--FSALKRHFKLYLTSSTERFSQNFKVVVVDGKNES-EYTVKWQDFFTG
.. .: . .: : : :::.: . .: ::..:: :. .:. .: .. ..::
NP_001 RAVSHEDQFLRLDFHAHGRHFNLRMKRDTSLFSDEFK---VETSNKVLDYDTS--HIYTG
60 70 80 90 100
120 130 140 150 160 170
pF1KE2 HVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVND-TKDKRMLVYKSEDIKNVS
:. :: : . . : :.: :. . .:: :...: : . ..:. .:: :
NP_001 HIYGEEGSFSHGSVIDGRFEGFIQTRGGTFYVEPAERYIKDRTLPFHSVIYHEDDI-NYP
110 120 130 140 150 160
180 190 200
pF1KE2 RLQSPKVCGYLKVDNEELLPKGLVDREPPEGKT
. .:.
NP_001 HKYGPQGGCADHSVFERMRKYQMTGVEEVTQIPQEEHAANGPELLRKKRTTSAEKNTCQL
170 180 190 200 210 220
209 residues in 1 query sequences
64092750 residues in 91774 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Tue Jul 16 16:01:02 2019 done: Tue Jul 16 16:01:03 2019
Total Scan time: 4.210 Total Display time: 0.010
Function used was FASTA [36.3.4 Apr, 2011]