Result of FASTA (ccds) for
pFN21AE1971
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE1971, 538 aa
1>>>pF1KE1971 538 - 538 aa - 538 aa
Library: human.CCDS.faa
18921897 residues in 33420 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.8464+/-0.000982; mu= 16.1218+/- 0.059
mean_var=81.7190+/-16.253, 0's: 0 Z-trim(104.7): 52 B-trim: 10 in 1/48
Lambda= 0.141877
statistics sampled from 8117 (8164) to 8117 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.62), E-opt: 0.2 (0.244), width: 16
Scan time: 1.590
The best scores are: opt bits E(33420)
CCDS42798.1 CASP8 gene_id:841|Hs109|chr2 ( 538) 3577 742.3 3.3e-214
CCDS2342.1 CASP8 gene_id:841|Hs109|chr2 ( 479) 3182 661.5 6.5e-190
CCDS2343.1 CASP8 gene_id:841|Hs109|chr2 ( 464) 1958 410.9 1.7e-114
CCDS42799.1 CASP8 gene_id:841|Hs109|chr2 ( 496) 1956 410.5 2.3e-114
CCDS2345.1 CASP8 gene_id:841|Hs109|chr2 ( 235) 1250 265.8 4e-71
CCDS2340.1 CASP10 gene_id:843|Hs109|chr2 ( 522) 732 160.0 6.4e-39
CCDS2339.1 CASP10 gene_id:843|Hs109|chr2 ( 479) 721 157.7 2.8e-38
CCDS56159.1 CASP10 gene_id:843|Hs109|chr2 ( 455) 657 144.6 2.4e-34
CCDS7580.1 CASP7 gene_id:840|Hs109|chr10 ( 336) 568 126.3 5.6e-29
CCDS58096.1 CASP7 gene_id:840|Hs109|chr10 ( 278) 566 125.9 6.4e-29
CCDS7581.1 CASP7 gene_id:840|Hs109|chr10 ( 303) 565 125.7 7.9e-29
CCDS73200.1 CASP7 gene_id:840|Hs109|chr10 ( 388) 565 125.8 9.7e-29
CCDS56160.1 CASP10 gene_id:843|Hs109|chr2 ( 478) 544 121.5 2.3e-27
CCDS2338.1 CASP10 gene_id:843|Hs109|chr2 ( 521) 531 118.9 1.5e-26
CCDS3684.1 CASP6 gene_id:839|Hs109|chr4 ( 293) 451 102.3 8.2e-22
CCDS5879.1 CASP2 gene_id:835|Hs109|chr7 ( 452) 421 96.3 8.2e-20
CCDS2337.1 CFLAR gene_id:8837|Hs109|chr2 ( 480) 411 94.3 3.6e-19
CCDS77505.1 CFLAR gene_id:8837|Hs109|chr2 ( 462) 406 93.2 7.1e-19
CCDS3836.1 CASP3 gene_id:836|Hs109|chr4 ( 277) 403 92.5 7.1e-19
CCDS159.2 CASP9 gene_id:842|Hs109|chr1 ( 333) 391 90.1 4.5e-18
CCDS158.1 CASP9 gene_id:842|Hs109|chr1 ( 416) 391 90.2 5.4e-18
CCDS87283.1 CASP3 gene_id:836|Hs109|chr4 ( 182) 363 84.2 1.5e-16
CCDS3685.1 CASP6 gene_id:839|Hs109|chr4 ( 204) 343 80.2 2.7e-15
CCDS12323.1 CASP14 gene_id:23581|Hs109|chr19 ( 242) 315 74.5 1.7e-13
CCDS56158.1 CFLAR gene_id:8837|Hs109|chr2 ( 384) 302 71.9 1.5e-12
CCDS59436.1 CFLAR gene_id:8837|Hs109|chr2 ( 366) 297 70.9 3e-12
CCDS77506.1 CASP10 gene_id:843|Hs109|chr2 ( 247) 292 69.8 4.4e-12
>>CCDS42798.1 CASP8 gene_id:841|Hs109|chr2 (538 aa)
initn: 3577 init1: 3577 opt: 3577 Z-score: 3959.4 bits: 742.3 E(33420): 3.3e-214
Smith-Waterman score: 3577; 99.8% identity (100.0% similar) in 538 aa overlap (1-538:1-538)
10 20 30 40 50 60
pF1KE1 MEGGRRARVVIESRRNFFLGAFPTPFPAEHVELGRLGDSETAMVPGKGGADYILLPFKKM
:::::::::::::.::::::::::::::::::::::::::::::::::::::::::::::
CCDS42 MEGGRRARVVIESKRNFFLGAFPTPFPAEHVELGRLGDSETAMVPGKGGADYILLPFKKM
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 DFSRNLYDIGEQLDSEDLASLKFLSLDYIPQRKQEPIKDALMLFQRLQEKRMLEESNLSF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS42 DFSRNLYDIGEQLDSEDLASLKFLSLDYIPQRKQEPIKDALMLFQRLQEKRMLEESNLSF
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 LKELLFRINRLDLLITYLNTRKEEMERELQTPGRAQISAYRVMLYQISEEVSRSELRSFK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS42 LKELLFRINRLDLLITYLNTRKEEMERELQTPGRAQISAYRVMLYQISEEVSRSELRSFK
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 FLLQEEISKCKLDDDMNLLDIFIEMEKRVILGEGKLDILKRVCAQINKSLLKIINDYEEF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS42 FLLQEEISKCKLDDDMNLLDIFIEMEKRVILGEGKLDILKRVCAQINKSLLKIINDYEEF
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE1 SKERSSSLEGSPDEFSNGEELCGVMTISDSPREQDSESQTLDKVYQMKSKPRGYCLIINN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS42 SKERSSSLEGSPDEFSNGEELCGVMTISDSPREQDSESQTLDKVYQMKSKPRGYCLIINN
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE1 HNFAKAREKVPKLHSIRDRNGTHLDAGALTTTFEELHFEIKPHDDCTVEQIYEILKIYQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS42 HNFAKAREKVPKLHSIRDRNGTHLDAGALTTTFEELHFEIKPHDDCTVEQIYEILKIYQL
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE1 MDHSNMDCFICCILSHGDKGIIYGTDGQEAPIYELTSQFTGLKCPSLAGKPKVFFIQACQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS42 MDHSNMDCFICCILSHGDKGIIYGTDGQEAPIYELTSQFTGLKCPSLAGKPKVFFIQACQ
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE1 GDNYQKGIPVETDSEEQPYLEMDLSSPQTRYIPDEADFLLGMATVNNCVSYRNPAEGTWY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS42 GDNYQKGIPVETDSEEQPYLEMDLSSPQTRYIPDEADFLLGMATVNNCVSYRNPAEGTWY
430 440 450 460 470 480
490 500 510 520 530
pF1KE1 IQSLCQSLRERCPRGDDILTILTEVNYEVSNKDDKKNMGKQMPQPTFTLRKKLVFPSD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS42 IQSLCQSLRERCPRGDDILTILTEVNYEVSNKDDKKNMGKQMPQPTFTLRKKLVFPSD
490 500 510 520 530
>>CCDS2342.1 CASP8 gene_id:841|Hs109|chr2 (479 aa)
initn: 3182 init1: 3182 opt: 3182 Z-score: 3523.2 bits: 661.5 E(33420): 6.5e-190
Smith-Waterman score: 3182; 100.0% identity (100.0% similar) in 479 aa overlap (60-538:1-479)
30 40 50 60 70 80
pF1KE1 HVELGRLGDSETAMVPGKGGADYILLPFKKMDFSRNLYDIGEQLDSEDLASLKFLSLDYI
::::::::::::::::::::::::::::::
CCDS23 MDFSRNLYDIGEQLDSEDLASLKFLSLDYI
10 20 30
90 100 110 120 130 140
pF1KE1 PQRKQEPIKDALMLFQRLQEKRMLEESNLSFLKELLFRINRLDLLITYLNTRKEEMEREL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS23 PQRKQEPIKDALMLFQRLQEKRMLEESNLSFLKELLFRINRLDLLITYLNTRKEEMEREL
40 50 60 70 80 90
150 160 170 180 190 200
pF1KE1 QTPGRAQISAYRVMLYQISEEVSRSELRSFKFLLQEEISKCKLDDDMNLLDIFIEMEKRV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS23 QTPGRAQISAYRVMLYQISEEVSRSELRSFKFLLQEEISKCKLDDDMNLLDIFIEMEKRV
100 110 120 130 140 150
210 220 230 240 250 260
pF1KE1 ILGEGKLDILKRVCAQINKSLLKIINDYEEFSKERSSSLEGSPDEFSNGEELCGVMTISD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS23 ILGEGKLDILKRVCAQINKSLLKIINDYEEFSKERSSSLEGSPDEFSNGEELCGVMTISD
160 170 180 190 200 210
270 280 290 300 310 320
pF1KE1 SPREQDSESQTLDKVYQMKSKPRGYCLIINNHNFAKAREKVPKLHSIRDRNGTHLDAGAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS23 SPREQDSESQTLDKVYQMKSKPRGYCLIINNHNFAKAREKVPKLHSIRDRNGTHLDAGAL
220 230 240 250 260 270
330 340 350 360 370 380
pF1KE1 TTTFEELHFEIKPHDDCTVEQIYEILKIYQLMDHSNMDCFICCILSHGDKGIIYGTDGQE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS23 TTTFEELHFEIKPHDDCTVEQIYEILKIYQLMDHSNMDCFICCILSHGDKGIIYGTDGQE
280 290 300 310 320 330
390 400 410 420 430 440
pF1KE1 APIYELTSQFTGLKCPSLAGKPKVFFIQACQGDNYQKGIPVETDSEEQPYLEMDLSSPQT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS23 APIYELTSQFTGLKCPSLAGKPKVFFIQACQGDNYQKGIPVETDSEEQPYLEMDLSSPQT
340 350 360 370 380 390
450 460 470 480 490 500
pF1KE1 RYIPDEADFLLGMATVNNCVSYRNPAEGTWYIQSLCQSLRERCPRGDDILTILTEVNYEV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS23 RYIPDEADFLLGMATVNNCVSYRNPAEGTWYIQSLCQSLRERCPRGDDILTILTEVNYEV
400 410 420 430 440 450
510 520 530
pF1KE1 SNKDDKKNMGKQMPQPTFTLRKKLVFPSD
:::::::::::::::::::::::::::::
CCDS23 SNKDDKKNMGKQMPQPTFTLRKKLVFPSD
460 470
>>CCDS2343.1 CASP8 gene_id:841|Hs109|chr2 (464 aa)
initn: 1953 init1: 1953 opt: 1958 Z-score: 2169.4 bits: 410.9 E(33420): 1.7e-114
Smith-Waterman score: 3046; 96.9% identity (96.9% similar) in 479 aa overlap (60-538:1-464)
30 40 50 60 70 80
pF1KE1 HVELGRLGDSETAMVPGKGGADYILLPFKKMDFSRNLYDIGEQLDSEDLASLKFLSLDYI
::::::::::::::::::::::::::::::
CCDS23 MDFSRNLYDIGEQLDSEDLASLKFLSLDYI
10 20 30
90 100 110 120 130 140
pF1KE1 PQRKQEPIKDALMLFQRLQEKRMLEESNLSFLKELLFRINRLDLLITYLNTRKEEMEREL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS23 PQRKQEPIKDALMLFQRLQEKRMLEESNLSFLKELLFRINRLDLLITYLNTRKEEMEREL
40 50 60 70 80 90
150 160 170 180 190 200
pF1KE1 QTPGRAQISAYRVMLYQISEEVSRSELRSFKFLLQEEISKCKLDDDMNLLDIFIEMEKRV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS23 QTPGRAQISAYRVMLYQISEEVSRSELRSFKFLLQEEISKCKLDDDMNLLDIFIEMEKRV
100 110 120 130 140 150
210 220 230 240 250 260
pF1KE1 ILGEGKLDILKRVCAQINKSLLKIINDYEEFSKERSSSLEGSPDEFSNGEELCGVMTISD
::::::::::::::::::::::::::::::::: ::::::::::::
CCDS23 ILGEGKLDILKRVCAQINKSLLKIINDYEEFSK---------------GEELCGVMTISD
160 170 180 190
270 280 290 300 310 320
pF1KE1 SPREQDSESQTLDKVYQMKSKPRGYCLIINNHNFAKAREKVPKLHSIRDRNGTHLDAGAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS23 SPREQDSESQTLDKVYQMKSKPRGYCLIINNHNFAKAREKVPKLHSIRDRNGTHLDAGAL
200 210 220 230 240 250
330 340 350 360 370 380
pF1KE1 TTTFEELHFEIKPHDDCTVEQIYEILKIYQLMDHSNMDCFICCILSHGDKGIIYGTDGQE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS23 TTTFEELHFEIKPHDDCTVEQIYEILKIYQLMDHSNMDCFICCILSHGDKGIIYGTDGQE
260 270 280 290 300 310
390 400 410 420 430 440
pF1KE1 APIYELTSQFTGLKCPSLAGKPKVFFIQACQGDNYQKGIPVETDSEEQPYLEMDLSSPQT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS23 APIYELTSQFTGLKCPSLAGKPKVFFIQACQGDNYQKGIPVETDSEEQPYLEMDLSSPQT
320 330 340 350 360 370
450 460 470 480 490 500
pF1KE1 RYIPDEADFLLGMATVNNCVSYRNPAEGTWYIQSLCQSLRERCPRGDDILTILTEVNYEV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS23 RYIPDEADFLLGMATVNNCVSYRNPAEGTWYIQSLCQSLRERCPRGDDILTILTEVNYEV
380 390 400 410 420 430
510 520 530
pF1KE1 SNKDDKKNMGKQMPQPTFTLRKKLVFPSD
:::::::::::::::::::::::::::::
CCDS23 SNKDDKKNMGKQMPQPTFTLRKKLVFPSD
440 450 460
>>CCDS42799.1 CASP8 gene_id:841|Hs109|chr2 (496 aa)
initn: 2590 init1: 1953 opt: 1956 Z-score: 2166.8 bits: 410.5 E(33420): 2.3e-114
Smith-Waterman score: 2972; 90.8% identity (90.8% similar) in 511 aa overlap (60-538:1-496)
30 40 50 60 70 80
pF1KE1 HVELGRLGDSETAMVPGKGGADYILLPFKKMDFSRNLYDIGEQLDSEDLASLKFLSLDYI
::::::::::::::::::::::::::::::
CCDS42 MDFSRNLYDIGEQLDSEDLASLKFLSLDYI
10 20 30
90 100 110 120 130 140
pF1KE1 PQRKQEPIKDALMLFQRLQEKRMLEESNLSFLKELLFRINRLDLLITYLNTRKEEMEREL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS42 PQRKQEPIKDALMLFQRLQEKRMLEESNLSFLKELLFRINRLDLLITYLNTRKEEMEREL
40 50 60 70 80 90
150 160 170
pF1KE1 QTPGRAQISAYR--------------------------------VMLYQISEEVSRSELR
:::::::::::: ::::::::::::::::
CCDS42 QTPGRAQISAYRFHFCRMSWAEANSQCQTQSVPFWRRVDHLLIRVMLYQISEEVSRSELR
100 110 120 130 140 150
180 190 200 210 220 230
pF1KE1 SFKFLLQEEISKCKLDDDMNLLDIFIEMEKRVILGEGKLDILKRVCAQINKSLLKIINDY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS42 SFKFLLQEEISKCKLDDDMNLLDIFIEMEKRVILGEGKLDILKRVCAQINKSLLKIINDY
160 170 180 190 200 210
240 250 260 270 280 290
pF1KE1 EEFSKERSSSLEGSPDEFSNGEELCGVMTISDSPREQDSESQTLDKVYQMKSKPRGYCLI
::::: ::::::::::::::::::::::::::::::::::::::::
CCDS42 EEFSK---------------GEELCGVMTISDSPREQDSESQTLDKVYQMKSKPRGYCLI
220 230 240 250
300 310 320 330 340 350
pF1KE1 INNHNFAKAREKVPKLHSIRDRNGTHLDAGALTTTFEELHFEIKPHDDCTVEQIYEILKI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS42 INNHNFAKAREKVPKLHSIRDRNGTHLDAGALTTTFEELHFEIKPHDDCTVEQIYEILKI
260 270 280 290 300 310
360 370 380 390 400 410
pF1KE1 YQLMDHSNMDCFICCILSHGDKGIIYGTDGQEAPIYELTSQFTGLKCPSLAGKPKVFFIQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS42 YQLMDHSNMDCFICCILSHGDKGIIYGTDGQEAPIYELTSQFTGLKCPSLAGKPKVFFIQ
320 330 340 350 360 370
420 430 440 450 460 470
pF1KE1 ACQGDNYQKGIPVETDSEEQPYLEMDLSSPQTRYIPDEADFLLGMATVNNCVSYRNPAEG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS42 ACQGDNYQKGIPVETDSEEQPYLEMDLSSPQTRYIPDEADFLLGMATVNNCVSYRNPAEG
380 390 400 410 420 430
480 490 500 510 520 530
pF1KE1 TWYIQSLCQSLRERCPRGDDILTILTEVNYEVSNKDDKKNMGKQMPQPTFTLRKKLVFPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS42 TWYIQSLCQSLRERCPRGDDILTILTEVNYEVSNKDDKKNMGKQMPQPTFTLRKKLVFPS
440 450 460 470 480 490
pF1KE1 D
:
CCDS42 D
>>CCDS2345.1 CASP8 gene_id:841|Hs109|chr2 (235 aa)
initn: 1250 init1: 1250 opt: 1250 Z-score: 1390.6 bits: 265.8 E(33420): 4e-71
Smith-Waterman score: 1250; 100.0% identity (100.0% similar) in 198 aa overlap (60-257:1-198)
30 40 50 60 70 80
pF1KE1 HVELGRLGDSETAMVPGKGGADYILLPFKKMDFSRNLYDIGEQLDSEDLASLKFLSLDYI
::::::::::::::::::::::::::::::
CCDS23 MDFSRNLYDIGEQLDSEDLASLKFLSLDYI
10 20 30
90 100 110 120 130 140
pF1KE1 PQRKQEPIKDALMLFQRLQEKRMLEESNLSFLKELLFRINRLDLLITYLNTRKEEMEREL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS23 PQRKQEPIKDALMLFQRLQEKRMLEESNLSFLKELLFRINRLDLLITYLNTRKEEMEREL
40 50 60 70 80 90
150 160 170 180 190 200
pF1KE1 QTPGRAQISAYRVMLYQISEEVSRSELRSFKFLLQEEISKCKLDDDMNLLDIFIEMEKRV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS23 QTPGRAQISAYRVMLYQISEEVSRSELRSFKFLLQEEISKCKLDDDMNLLDIFIEMEKRV
100 110 120 130 140 150
210 220 230 240 250 260
pF1KE1 ILGEGKLDILKRVCAQINKSLLKIINDYEEFSKERSSSLEGSPDEFSNGEELCGVMTISD
::::::::::::::::::::::::::::::::::::::::::::::::
CCDS23 ILGEGKLDILKRVCAQINKSLLKIINDYEEFSKERSSSLEGSPDEFSNDFGQSLPNEKQT
160 170 180 190 200 210
270 280 290 300 310 320
pF1KE1 SPREQDSESQTLDKVYQMKSKPRGYCLIINNHNFAKAREKVPKLHSIRDRNGTHLDAGAL
CCDS23 SGILSDHQQSQFCKSTGESAQTSQH
220 230
>>CCDS2340.1 CASP10 gene_id:843|Hs109|chr2 (522 aa)
initn: 984 init1: 362 opt: 732 Z-score: 812.4 bits: 160.0 E(33420): 6.4e-39
Smith-Waterman score: 988; 37.8% identity (62.2% similar) in 519 aa overlap (59-536:17-514)
30 40 50 60 70 80
pF1KE1 EHVELGRLGDSETAMVPGKGGADYILLPFKKMDFSRNLYDIGEQLDSEDLASLKFLSLDY
:..: ..: : .: .:. .:::: .
CCDS23 MKSQGQHWYSSSDKNCKVSFREKLLIIDSNLGVQDVENLKFLCIGL
10 20 30 40
90 100 110 120 130 140
pF1KE1 IPQRKQEPIKDALMLFQRLQEKRMLEESNLSFLKELLFRINRLDLLITYLNTRKEEMERE
.:..: : ..: .:..: . .: : . :: :::. : : :. .:: :::.::
CCDS23 VPNKKLEKSSSASDVFEHLLAEDLLSEEDPFFLAELLY-IIRQKKLLQHLNCTKEEVERL
50 60 70 80 90 100
150 160 170 180 190 200
pF1KE1 LQTPGRAQISAYRVMLYQISEEVSRSELRSFKFLLQEEISKCKLDDDMNLLDIFIEMEKR
: : : ..: .: .::..:: .. .:... :::.. . : .:. :... .::.
CCDS23 L--PTRQRVSLFRNLLYELSEGIDSENLKDMIFLLKDSLPKT----EMTSLSFLAFLEKQ
110 120 130 140 150
210 220 230 240
pF1KE1 VILGEGKLDILKRVCAQINKSLLKIINDYEE----------FSKERSSS-----------
. : .: :. .: . .::. :. :.. .:: :
CCDS23 GKIDEDNLTCLEDLCKTVVPKLLRNIEKYKREKAIQIVTPPVDKEAESYQGEEELVSQTD
160 170 180 190 200 210
250 260 270 280
pF1KE1 ----LEGSPDEF-------SNGEELC-GVMTISD------SPREQDSESQTLDK-VYQMK
::. :.: :::.. :. .. . : .::..: ::.:.
CCDS23 VKTFLEALPQESWQNKHAGSNGNRATNGAPSLVSRGMQGASANTLNSETSTKRAAVYRMN
220 230 240 250 260 270
290 300 310 320 330 340
pF1KE1 SKPRGYCLIINNHNFAKAREKVPKLHSIRDRNGTHLDAGALTTTFEELHFEIKPHDDCTV
. :: :.:.:::.:. :..::.::: :: :. .:. : : .. :.. :
CCDS23 RNHRGLCVIVNNHSFT----------SLKDRQGTHKDAEILSHVFQWLGFTVHIHNNVTK
280 290 300 310 320
350 360 370 380 390 400
pF1KE1 EQIYEILKIYQLMD-HSNMDCFICCILSHGDKGIIYGTDGQEAPIYELTSQFTGLKCPSL
.. .:. . :.. :::. :::.:: : .:..: :: :. :.::.:.:: :
CCDS23 VEMEMVLQKQKCNPAHADGDCFVFCILTHGRFGAVYSSDEALIPIREIMSHFTALQCPRL
330 340 350 360 370 380
410 420 430 440 450 460
pF1KE1 AGKPKVFFIQACQGDNYQKGIPVETDSEEQPYLEMDLSSPQTRYIPDEADFLLGMATVNN
: :::.::::::::.. : .. .:.:. . : :. .: : :: :::::::.::: .
CCDS23 AEKPKLFFIQACQGEEIQPSVSIEADALN-P--EQAPTSLQDS-IPAEADFLLGLATVPG
390 400 410 420 430 440
470 480 490 500 510 520
pF1KE1 CVSYRNPAEGTWYIQSLCQSLRERCPRGDDILTILTEVNYEVSNKDDKKNMGKQMPQPTF
::.:. ::.:::::::. :.. :: .:::.::: :: .:: . ::.. ::::::.:
CCDS23 YVSFRHVEEGSWYIQSLCNHLKKLVPRHEDILSILTAVNDDVSRRVDKQGTKKQMPQPAF
450 460 470 480 490 500
530
pF1KE1 TLRKKLVFPSD
:::::::::
CCDS23 TLRKKLVFPVPLDALSL
510 520
>>CCDS2339.1 CASP10 gene_id:843|Hs109|chr2 (479 aa)
initn: 984 init1: 362 opt: 721 Z-score: 800.8 bits: 157.7 E(33420): 2.8e-38
Smith-Waterman score: 1038; 39.3% identity (65.4% similar) in 483 aa overlap (59-536:17-471)
30 40 50 60 70 80
pF1KE1 EHVELGRLGDSETAMVPGKGGADYILLPFKKMDFSRNLYDIGEQLDSEDLASLKFLSLDY
:..: ..: : .: .:. .:::: .
CCDS23 MKSQGQHWYSSSDKNCKVSFREKLLIIDSNLGVQDVENLKFLCIGL
10 20 30 40
90 100 110 120 130 140
pF1KE1 IPQRKQEPIKDALMLFQRLQEKRMLEESNLSFLKELLFRINRLDLLITYLNTRKEEMERE
.:..: : ..: .:..: . .: : . :: :::. : : :. .:: :::.::
CCDS23 VPNKKLEKSSSASDVFEHLLAEDLLSEEDPFFLAELLY-IIRQKKLLQHLNCTKEEVERL
50 60 70 80 90 100
150 160 170 180 190 200
pF1KE1 LQTPGRAQISAYRVMLYQISEEVSRSELRSFKFLLQEEISKCKLDDDMNLLDIFIEMEKR
: : : ..: .: .::..:: .. .:... :::.. . : .:. :... .::.
CCDS23 L--PTRQRVSLFRNLLYELSEGIDSENLKDMIFLLKDSLPKT----EMTSLSFLAFLEKQ
110 120 130 140 150
210 220 230 240 250 260
pF1KE1 VILGEGKLDILKRVCAQINKSLLKIINDYEEFSKERSSSLEGSP-D---EFSNGEELCGV
. : .: :. .: . .::. : :....:.. .. : : : .:::
CCDS23 GKIDEDNLTCLEDLCKTVVPKLLRNI---EKYKREKAIQIVTPPVDKEAESYQGEE----
160 170 180 190 200 210
270 280 290 300 310 320
pF1KE1 MTISDSPREQDSESQTLDKVYQMKSKPRGYCLIINNHNFAKAREKVPKLHSIRDRNGTHL
.:.. . :. ::.:. . :: :.:.:::.:. :..::.:::
CCDS23 ELVSQTDVKTFLEALPRAAVYRMNRNHRGLCVIVNNHSFT----------SLKDRQGTHK
220 230 240 250 260
330 340 350 360 370 380
pF1KE1 DAGALTTTFEELHFEIKPHDDCTVEQIYEILKIYQLMD-HSNMDCFICCILSHGDKGIIY
:: :. .:. : : .. :.. : .. .:. . :.. :::. :::.:: : .:
CCDS23 DAEILSHVFQWLGFTVHIHNNVTKVEMEMVLQKQKCNPAHADGDCFVFCILTHGRFGAVY
270 280 290 300 310 320
390 400 410 420 430 440
pF1KE1 GTDGQEAPIYELTSQFTGLKCPSLAGKPKVFFIQACQGDNYQKGIPVETDSEEQPYLEMD
..: :: :. :.::.:.:: :: :::.::::::::.. : .. .:.:. . : :.
CCDS23 SSDEALIPIREIMSHFTALQCPRLAEKPKLFFIQACQGEEIQPSVSIEADALN-P--EQA
330 340 350 360 370
450 460 470 480 490 500
pF1KE1 LSSPQTRYIPDEADFLLGMATVNNCVSYRNPAEGTWYIQSLCQSLRERCPRGDDILTILT
.: : :: :::::::.::: . ::.:. ::.:::::::. :.. :: .:::.:::
CCDS23 PTSLQDS-IPAEADFLLGLATVPGYVSFRHVEEGSWYIQSLCNHLKKLVPRHEDILSILT
380 390 400 410 420 430
510 520 530
pF1KE1 EVNYEVSNKDDKKNMGKQMPQPTFTLRKKLVFPSD
:: .:: . ::.. ::::::.::::::::::
CCDS23 AVNDDVSRRVDKQGTKKQMPQPAFTLRKKLVFPVPLDALSL
440 450 460 470
>>CCDS56159.1 CASP10 gene_id:843|Hs109|chr2 (455 aa)
initn: 823 init1: 362 opt: 657 Z-score: 730.4 bits: 144.6 E(33420): 2.4e-34
Smith-Waterman score: 889; 36.1% identity (62.6% similar) in 479 aa overlap (59-536:17-447)
30 40 50 60 70 80
pF1KE1 EHVELGRLGDSETAMVPGKGGADYILLPFKKMDFSRNLYDIGEQLDSEDLASLKFLSLDY
:..: ..: : .: .:. .:::: .
CCDS56 MKSQGQHWYSSSDKNCKVSFREKLLIIDSNLGVQDVENLKFLCIGL
10 20 30 40
90 100 110 120 130 140
pF1KE1 IPQRKQEPIKDALMLFQRLQEKRMLEESNLSFLKELLFRINRLDLLITYLNTRKEEMERE
.:..: : ..: .:..: . .: : . :: :::. : : :. .:: :::.::
CCDS56 VPNKKLEKSSSASDVFEHLLAEDLLSEEDPFFLAELLY-IIRQKKLLQHLNCTKEEVERL
50 60 70 80 90 100
150 160 170 180 190 200
pF1KE1 LQTPGRAQISAYRVMLYQISEEVSRSELRSFKFLLQEEISKCKLDDDMNLLDIFIEMEKR
: : : ..: .: .::..:: .. .:... :::.. . : .:. :... .::.
CCDS56 L--PTRQRVSLFRNLLYELSEGIDSENLKDMIFLLKDSLPKT----EMTSLSFLAFLEKQ
110 120 130 140 150
210 220 230 240 250 260
pF1KE1 VILGEGKLDILKRVCAQINKSLLKIINDYEEFSKERSSSLEGSPDEFSNGEELCGVMTIS
. : .: :. .: . .::. : :....:.. . :
CCDS56 GKIDEDNLTCLEDLCKTVVPKLLRNI---EKYKREKA-------------------IQIV
160 170 180 190
270 280 290 300 310 320
pF1KE1 DSPREQDSESQTLDKVYQMKSKPRGYCLIINNHNFAKAREKVPKLHSIRDRNGTHLDAGA
: ....:: :: : .... . : .:. .: ..... .
CCDS56 TPPVDKEAES------YQ------GEEELVSQTDVKTFLEALPQ-ESWQNKHAGSNEI--
200 210 220 230 240
330 340 350 360 370 380
pF1KE1 LTTTFEELHFEIKPHDDCTVEQIYEILKIYQLMD-HSNMDCFICCILSHGDKGIIYGTDG
:. .:. : : .. :.. : .. .:. . :.. :::. :::.:: : .:..:
CCDS56 LSHVFQWLGFTVHIHNNVTKVEMEMVLQKQKCNPAHADGDCFVFCILTHGRFGAVYSSDE
250 260 270 280 290 300
390 400 410 420 430 440
pF1KE1 QEAPIYELTSQFTGLKCPSLAGKPKVFFIQACQGDNYQKGIPVETDSEEQPYLEMDLSSP
:: :. :.::.:.:: :: :::.::::::::.. : .. .:.:. . : :. .:
CCDS56 ALIPIREIMSHFTALQCPRLAEKPKLFFIQACQGEEIQPSVSIEADALN-P--EQAPTSL
310 320 330 340 350
450 460 470 480 490 500
pF1KE1 QTRYIPDEADFLLGMATVNNCVSYRNPAEGTWYIQSLCQSLRERCPRGDDILTILTEVNY
: :: :::::::.::: . ::.:. ::.:::::::. :.. :: .:::.::: ::
CCDS56 QDS-IPAEADFLLGLATVPGYVSFRHVEEGSWYIQSLCNHLKKLVPRHEDILSILTAVND
360 370 380 390 400 410
510 520 530
pF1KE1 EVSNKDDKKNMGKQMPQPTFTLRKKLVFPSD
.:: . ::.. ::::::.::::::::::
CCDS56 DVSRRVDKQGTKKQMPQPAFTLRKKLVFPVPLDALSL
420 430 440 450
>>CCDS7580.1 CASP7 gene_id:840|Hs109|chr10 (336 aa)
initn: 508 init1: 218 opt: 568 Z-score: 633.9 bits: 126.3 E(33420): 5.6e-29
Smith-Waterman score: 568; 36.4% identity (62.7% similar) in 327 aa overlap (222-535:26-334)
200 210 220 230 240
pF1KE1 LDDDMNLLDIFIEMEKRVILGEGKLDILKRVCAQINKSLLKIINDYEEFSKERSS---SL
.::. .. . :: . : :. :.
CCDS75 MDCVGWPPGRKWHLEKNTSCGGSSGICASYVTQMADDQGCIEEQGVEDSANEDSV
10 20 30 40 50
250 260 270 280 290 300
pF1KE1 EGSPDEFSNGEELCGVMTISDSPREQDSESQTLDKV----YQMKSKPRGYCLIINNHNFA
...::. : : . . . : : . : :.: :.:. . : :.::::.::
CCDS75 DAKPDRSSFVPSLFSKKKKNVTMR---SIKTTRDRVPTYQYNMNFEKLGKCIIINNKNF-
60 70 80 90 100 110
310 320 330 340 350 360
pF1KE1 KAREKVPKLHSIRDRNGTHLDAGALTTTFEELHFEIKPHDDCTVEQIYEILKIYQLMDHS
.:: . :::: :: :: :. : :.. ..::. .. ..:: . ::.
CCDS75 ---DKVTGMGV---RNGTDKDAEALFKCFRSLGFDVIVYNDCSCAKMQDLLKKASEEDHT
120 130 140 150 160
370 380 390 400 410 420
pF1KE1 NMDCFICCILSHGDKGIIYGTDGQEAPIYELTSQFTGLKCPSLAGKPKVFFIQACQGDNY
: :: : .::::....::: :: .:: .::..: : .: .: :::.::::::.: .
CCDS75 NAACFACILLSHGEENVIYGKDGV-TPIKDLTAHFRGDRCKTLLEKPKLFFIQACRGTEL
170 180 190 200 210 220
430 440 450 460 470 480
pF1KE1 QKGIPVETDSEEQPYLEMDLSSPQTRYIPDEADFLLGMATVNNCVSYRNPAEGTWYIQSL
. :: ..:: : . : ..:. . :: :::::....:: . :.:.:..:.:..:.:
CCDS75 DDGI--QADS--GPINDTD-ANPRYK-IPVEADFLFAYSTVPGYYSWRSPGRGSWFVQAL
230 240 250 260 270
490 500 510 520 530
pF1KE1 CQSLRERCPRGDDILTILTEVNYEV-----SNKDDKK-NMGKQMPQPTFTLRKKLVFPSD
:. :.:. . .:. :::.:: .: :..:: . . ::.: . : :.: :
CCDS75 CSILEEH-GKDLEIMQILTRVNDRVARHFESQSDDPHFHEKKQIPCVVSMLTKELYFSQ
280 290 300 310 320 330
>>CCDS58096.1 CASP7 gene_id:840|Hs109|chr10 (278 aa)
initn: 508 init1: 218 opt: 566 Z-score: 632.9 bits: 125.9 E(33420): 6.4e-29
Smith-Waterman score: 566; 37.2% identity (65.6% similar) in 288 aa overlap (263-535:4-276)
240 250 260 270 280
pF1KE1 IINDYEEFSKERSSSLEGSPDEFSNGEELCGVMTISDSPREQDSESQ-----TLDKV---
:... .:. ... . .. : :.:
CCDS58 MQRGLFSDGDTSKKKKNVTMRSIKTTRDRVPTY
10 20 30
290 300 310 320 330 340
pF1KE1 -YQMKSKPRGYCLIINNHNFAKAREKVPKLHSIRDRNGTHLDAGALTTTFEELHFEIKPH
:.:. . : :.::::.:: :. .. :::: :: :: :. : :.. .
CCDS58 QYNMNFEKLGKCIIINNKNF-------DKVTGMGVRNGTDKDAEALFKCFRSLGFDVIVY
40 50 60 70 80
350 360 370 380 390 400
pF1KE1 DDCTVEQIYEILKIYQLMDHSNMDCFICCILSHGDKGIIYGTDGQEAPIYELTSQFTGLK
.::. .. ..:: . ::.: :: : .::::....::: :: .:: .::..: : .
CCDS58 NDCSCAKMQDLLKKASEEDHTNAACFACILLSHGEENVIYGKDGV-TPIKDLTAHFRGDR
90 100 110 120 130 140
410 420 430 440 450 460
pF1KE1 CPSLAGKPKVFFIQACQGDNYQKGIPVETDSEEQPYLEMDLSSPQTRYIPDEADFLLGMA
: .: :::.::::::.: . . :: ..:: : . : ..:. . :: :::::....
CCDS58 CKTLLEKPKLFFIQACRGTELDDGI--QADS--GPINDTD-ANPRYK-IPVEADFLFAYS
150 160 170 180 190
470 480 490 500 510
pF1KE1 TVNNCVSYRNPAEGTWYIQSLCQSLRERCPRGDDILTILTEVNYEV-----SNKDDKK-N
:: . :.:.:..:.:..:.::. :.:. . .:. :::.:: .: :..:: . .
CCDS58 TVPGYYSWRSPGRGSWFVQALCSILEEH-GKDLEIMQILTRVNDRVARHFESQSDDPHFH
200 210 220 230 240 250
520 530
pF1KE1 MGKQMPQPTFTLRKKLVFPSD
::.: . : :.: :
CCDS58 EKKQIPCVVSMLTKELYFSQ
260 270
538 residues in 1 query sequences
18921897 residues in 33420 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Thu Oct 24 21:32:06 2019 done: Thu Oct 24 21:32:06 2019
Total Scan time: 1.590 Total Display time: 0.080
Function used was FASTA [36.3.4 Apr, 2011]