Result of FASTA (omim) for
pFN21AE1010
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE1010, 224 aa
1>>>pF1KE1010 224 - 224 aa - 224 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 8.9336+/-0.000325; mu= -1.4335+/- 0.020
mean_var=283.1938+/-56.313, 0's: 0 Z-trim(124.8): 30 B-trim: 527 in 1/60
Lambda= 0.076214
statistics sampled from 47267 (47303) to 47267 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.833), E-opt: 0.2 (0.555), width: 16
Scan time: 7.620
The best scores are: opt bits E(85289)
NP_001034929 (OMIM: 300922) cysteine-rich hydropho ( 224) 1524 179.7 3.4e-45
NP_001287813 (OMIM: 300922) cysteine-rich hydropho ( 204) 1279 152.7 4.1e-37
XP_016885071 (OMIM: 300922) PREDICTED: cysteine-ri ( 172) 1145 137.9 1e-32
NP_036242 (OMIM: 604332) cysteine-rich hydrophobic ( 165) 941 115.5 5.5e-26
XP_016885072 (OMIM: 300922) PREDICTED: cysteine-ri ( 123) 787 98.4 5.6e-21
XP_016885073 (OMIM: 300922) PREDICTED: cysteine-ri ( 119) 749 94.2 1e-19
XP_011532684 (OMIM: 604332) PREDICTED: cysteine-ri ( 131) 603 78.2 7.2e-15
XP_006714100 (OMIM: 604332) PREDICTED: cysteine-ri ( 137) 369 52.5 4.1e-07
>>NP_001034929 (OMIM: 300922) cysteine-rich hydrophobic (224 aa)
initn: 1524 init1: 1524 opt: 1524 Z-score: 932.3 bits: 179.7 E(85289): 3.4e-45
Smith-Waterman score: 1524; 100.0% identity (100.0% similar) in 224 aa overlap (1-224:1-224)
10 20 30 40 50 60
pF1KE1 MSILLPNMAEFDTISELEEEEEEEAATSSSSPSSSSSVSGPDDDEEDEEEEEEEEEEEEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MSILLPNMAEFDTISELEEEEEEEAATSSSSPSSSSSVSGPDDDEEDEEEEEEEEEEEEE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 EEEEEEEEAPPPPRVVSEEHLRRYAPDPVLVRGAGHITVFGLSNKFDTEFPSVLTGKVAP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EEEEEEEEAPPPPRVVSEEHLRRYAPDPVLVRGAGHITVFGLSNKFDTEFPSVLTGKVAP
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 EEFKTSIGRVNACLKKALPVNVKWLLCGCLCCCCTLGCSLWPVICLNKRTRRSIQKLIEW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EEFKTSIGRVNACLKKALPVNVKWLLCGCLCCCCTLGCSLWPVICLNKRTRRSIQKLIEW
130 140 150 160 170 180
190 200 210 220
pF1KE1 ENNRLYHKLALHWKLTKRKCETSNMMEYVILIEFLPKYPIFRPD
::::::::::::::::::::::::::::::::::::::::::::
NP_001 ENNRLYHKLALHWKLTKRKCETSNMMEYVILIEFLPKYPIFRPD
190 200 210 220
>>NP_001287813 (OMIM: 300922) cysteine-rich hydrophobic (204 aa)
initn: 1772 init1: 1279 opt: 1279 Z-score: 787.2 bits: 152.7 E(85289): 4.1e-37
Smith-Waterman score: 1335; 91.1% identity (91.1% similar) in 224 aa overlap (1-224:1-204)
10 20 30 40 50 60
pF1KE1 MSILLPNMAEFDTISELEEEEEEEAATSSSSPSSSSSVSGPDDDEEDEEEEEEEEEEEEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MSILLPNMAEFDTISELEEEEEEEAATSSSSPSSSSSVSGPDDDEEDEEEEEEEEEEEEE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 EEEEEEEEAPPPPRVVSEEHLRRYAPDPVLVRGAGHITVFGLSNKFDTEFPSVLTGKVAP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EEEEEEEEAPPPPRVVSEEHLRRYAPDPVLVRGAGHITVFGLSNKFDTEFPSVLTGKVAP
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 EEFKTSIGRVNACLKKALPVNVKWLLCGCLCCCCTLGCSLWPVICLNKRTRRSIQKLIEW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EEFKTSIGRVNACLKKALPVNVKWLLCGCLCCCCTLGCSLWPVICLNKRTRRSIQKLIEW
130 140 150 160 170 180
190 200 210 220
pF1KE1 ENNRLYHKLALHWKLTKRKCETSNMMEYVILIEFLPKYPIFRPD
:::::::: ::::::::::::::::
NP_001 ENNRLYHK--------------------VILIEFLPKYPIFRPD
190 200
>>XP_016885071 (OMIM: 300922) PREDICTED: cysteine-rich h (172 aa)
initn: 1145 init1: 1145 opt: 1145 Z-score: 708.5 bits: 137.9 E(85289): 1e-32
Smith-Waterman score: 1145; 100.0% identity (100.0% similar) in 169 aa overlap (1-169:1-169)
10 20 30 40 50 60
pF1KE1 MSILLPNMAEFDTISELEEEEEEEAATSSSSPSSSSSVSGPDDDEEDEEEEEEEEEEEEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MSILLPNMAEFDTISELEEEEEEEAATSSSSPSSSSSVSGPDDDEEDEEEEEEEEEEEEE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 EEEEEEEEAPPPPRVVSEEHLRRYAPDPVLVRGAGHITVFGLSNKFDTEFPSVLTGKVAP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EEEEEEEEAPPPPRVVSEEHLRRYAPDPVLVRGAGHITVFGLSNKFDTEFPSVLTGKVAP
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 EEFKTSIGRVNACLKKALPVNVKWLLCGCLCCCCTLGCSLWPVICLNKRTRRSIQKLIEW
:::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EEFKTSIGRVNACLKKALPVNVKWLLCGCLCCCCTLGCSLWPVICLNKRVWT
130 140 150 160 170
190 200 210 220
pF1KE1 ENNRLYHKLALHWKLTKRKCETSNMMEYVILIEFLPKYPIFRPD
>>NP_036242 (OMIM: 604332) cysteine-rich hydrophobic dom (165 aa)
initn: 970 init1: 923 opt: 941 Z-score: 587.5 bits: 115.5 E(85289): 5.5e-26
Smith-Waterman score: 941; 78.0% identity (91.1% similar) in 168 aa overlap (57-224:5-165)
30 40 50 60 70 80
pF1KE1 TSSSSPSSSSSVSGPDDDEEDEEEEEEEEEEEEEEEEEEEEEAPPPPRVVSEEHLRRYAP
.: ::::.::.: ::.: .:.:
NP_036 MADFDEIYEEEEDEERA-------LEEQLLKYSP
10 20
90 100 110 120 130 140
pF1KE1 DPVLVRGAGHITVFGLSNKFDTEFPSVLTGKVAPEEFKTSIGRVNACLKKALPVNVKWLL
:::.:::.::.:::::::::..:::: :::::::::::.::.:::.:::: :::::.:::
NP_036 DPVVVRGSGHVTVFGLSNKFESEFPSSLTGKVAPEEFKASINRVNSCLKKNLPVNVRWLL
30 40 50 60 70 80
150 160 170 180 190 200
pF1KE1 CGCLCCCCTLGCSLWPVICLNKRTRRSIQKLIEWENNRLYHKLALHWKLTKRKCETSNMM
:::::::::::::.::::::.:::::::.::.::::::::::: :::.:.::::::.:::
NP_036 CGCLCCCCTLGCSMWPVICLSKRTRRSIEKLLEWENNRLYHKLCLHWRLSKRKCETNNMM
90 100 110 120 130 140
210 220
pF1KE1 EYVILIEFLPKYPIFRPD
::::::::::: ::::::
NP_036 EYVILIEFLPKTPIFRPD
150 160
>>XP_016885072 (OMIM: 300922) PREDICTED: cysteine-rich h (123 aa)
initn: 787 init1: 787 opt: 787 Z-score: 497.6 bits: 98.4 E(85289): 5.6e-21
Smith-Waterman score: 787; 95.6% identity (99.1% similar) in 113 aa overlap (112-224:11-123)
90 100 110 120 130 140
pF1KE1 RRYAPDPVLVRGAGHITVFGLSNKFDTEFPSVLTGKVAPEEFKTSIGRVNACLKKALPVN
.. .:.::::::::::::::::::::::::
XP_016 MDRGKGEKKLNIAVGEVAPEEFKTSIGRVNACLKKALPVN
10 20 30 40
150 160 170 180 190 200
pF1KE1 VKWLLCGCLCCCCTLGCSLWPVICLNKRTRRSIQKLIEWENNRLYHKLALHWKLTKRKCE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VKWLLCGCLCCCCTLGCSLWPVICLNKRTRRSIQKLIEWENNRLYHKLALHWKLTKRKCE
50 60 70 80 90 100
210 220
pF1KE1 TSNMMEYVILIEFLPKYPIFRPD
:::::::::::::::::::::::
XP_016 TSNMMEYVILIEFLPKYPIFRPD
110 120
>>XP_016885073 (OMIM: 300922) PREDICTED: cysteine-rich h (119 aa)
initn: 749 init1: 749 opt: 749 Z-score: 475.2 bits: 94.2 E(85289): 1e-19
Smith-Waterman score: 749; 100.0% identity (100.0% similar) in 117 aa overlap (1-117:1-117)
10 20 30 40 50 60
pF1KE1 MSILLPNMAEFDTISELEEEEEEEAATSSSSPSSSSSVSGPDDDEEDEEEEEEEEEEEEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MSILLPNMAEFDTISELEEEEEEEAATSSSSPSSSSSVSGPDDDEEDEEEEEEEEEEEEE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 EEEEEEEEAPPPPRVVSEEHLRRYAPDPVLVRGAGHITVFGLSNKFDTEFPSVLTGKVAP
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EEEEEEEEAPPPPRVVSEEHLRRYAPDPVLVRGAGHITVFGLSNKFDTEFPSVLTGKKF
70 80 90 100 110
130 140 150 160 170 180
pF1KE1 EEFKTSIGRVNACLKKALPVNVKWLLCGCLCCCCTLGCSLWPVICLNKRTRRSIQKLIEW
>>XP_011532684 (OMIM: 604332) PREDICTED: cysteine-rich h (131 aa)
initn: 625 init1: 578 opt: 603 Z-score: 387.9 bits: 78.2 E(85289): 7.2e-15
Smith-Waterman score: 603; 69.4% identity (86.8% similar) in 121 aa overlap (57-177:5-118)
30 40 50 60 70 80
pF1KE1 TSSSSPSSSSSVSGPDDDEEDEEEEEEEEEEEEEEEEEEEEEAPPPPRVVSEEHLRRYAP
.: ::::.::.: ::.: .:.:
XP_011 MADFDEIYEEEEDEERA-------LEEQLLKYSP
10 20
90 100 110 120 130 140
pF1KE1 DPVLVRGAGHITVFGLSNKFDTEFPSVLTGKVAPEEFKTSIGRVNACLKKALPVNVKWLL
:::.:::.::.:::::::::..:::: :::::::::::.::.:::.:::: :::::.:::
XP_011 DPVVVRGSGHVTVFGLSNKFESEFPSSLTGKVAPEEFKASINRVNSCLKKNLPVNVRWLL
30 40 50 60 70 80
150 160 170 180 190 200
pF1KE1 CGCLCCCCTLGCSLWPVICLNKRTRRSIQKLIEWENNRLYHKLALHWKLTKRKCETSNMM
:::::::::::::.::::::.:: ..:..
XP_011 CGCLCCCCTLGCSMWPVICLSKRITFALQNIFSSLDPQLILSLL
90 100 110 120 130
210 220
pF1KE1 EYVILIEFLPKYPIFRPD
>>XP_006714100 (OMIM: 604332) PREDICTED: cysteine-rich h (137 aa)
initn: 474 init1: 351 opt: 369 Z-score: 248.6 bits: 52.5 E(85289): 4.1e-07
Smith-Waterman score: 645; 63.1% identity (74.4% similar) in 168 aa overlap (57-224:5-137)
30 40 50 60 70 80
pF1KE1 TSSSSPSSSSSVSGPDDDEEDEEEEEEEEEEEEEEEEEEEEEAPPPPRVVSEEHLRRYAP
.: ::::.::.: ::.: .:.:
XP_006 MADFDEIYEEEEDEERA-------LEEQLLKYSP
10 20
90 100 110 120 130 140
pF1KE1 DPVLVRGAGHITVFGLSNKFDTEFPSVLTGKVAPEEFKTSIGRVNACLKKALPVNVKWLL
:::.:::.::.:::::::::..:::: :::::::::::.::.:::.:::: ::::
XP_006 DPVVVRGSGHVTVFGLSNKFESEFPSSLTGKVAPEEFKASINRVNSCLKKNLPVN-----
30 40 50 60 70 80
150 160 170 180 190 200
pF1KE1 CGCLCCCCTLGCSLWPVICLNKRTRRSIQKLIEWENNRLYHKLALHWKLTKRKCETSNMM
:::::.::.::::::::::: :::.:.::::::.:::
XP_006 -----------------------TRRSIEKLLEWENNRLYHKLCLHWRLSKRKCETNNMM
90 100 110
210 220
pF1KE1 EYVILIEFLPKYPIFRPD
::::::::::: ::::::
XP_006 EYVILIEFLPKTPIFRPD
120 130
224 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sat Nov 5 13:23:23 2016 done: Sat Nov 5 13:23:24 2016
Total Scan time: 7.620 Total Display time: -0.030
Function used was FASTA [36.3.4 Apr, 2011]