Result of FASTA (omim) for
pFN21AB4741
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB4741, 1145 aa
1>>>pF1KB4741 1145 - 1145 aa - 1145 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 6.7371+/-0.000453; mu= 14.9288+/- 0.028
mean_var=107.1389+/-19.920, 0's: 0 Z-trim(113.2): 414 B-trim: 157 in 1/54
Lambda= 0.123908
statistics sampled from 21981 (22428) to 21981 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.617), E-opt: 0.2 (0.263), width: 16
Scan time: 10.800
The best scores are: opt bits E(85289)
NP_563578 (OMIM: 151460,608971,609532) receptor-ty (1145) 7726 1393.0 0
XP_006711537 (OMIM: 151460,608971,609532) PREDICTE (1192) 7515 1355.3 0
XP_006711535 (OMIM: 151460,608971,609532) PREDICTE (1258) 7515 1355.3 0
XP_006711536 (OMIM: 151460,608971,609532) PREDICTE (1240) 7510 1354.5 0
NP_002829 (OMIM: 151460,608971,609532) receptor-ty (1306) 7510 1354.5 0
NP_543031 (OMIM: 176884) receptor-type tyrosine-pr ( 793) 1069 202.9 6.3e-51
NP_543030 (OMIM: 176884) receptor-type tyrosine-pr ( 793) 1069 202.9 6.3e-51
NP_002827 (OMIM: 176884) receptor-type tyrosine-pr ( 802) 1069 202.9 6.3e-51
XP_011538298 (OMIM: 600926) PREDICTED: receptor-ty ( 678) 996 189.9 4.7e-47
XP_011538296 (OMIM: 600926) PREDICTED: receptor-ty ( 719) 993 189.3 7.1e-47
NP_569119 (OMIM: 600926) receptor-type tyrosine-pr ( 642) 992 189.1 7.3e-47
NP_001310283 (OMIM: 600926) receptor-type tyrosine ( 700) 992 189.1 7.9e-47
NP_006495 (OMIM: 600926) receptor-type tyrosine-pr ( 700) 992 189.1 7.9e-47
XP_016871957 (OMIM: 600926) PREDICTED: receptor-ty ( 700) 992 189.1 7.9e-47
NP_001303606 (OMIM: 600926) receptor-type tyrosine ( 700) 992 189.1 7.9e-47
XP_005252748 (OMIM: 600926) PREDICTED: receptor-ty ( 700) 992 189.1 7.9e-47
NP_001303605 (OMIM: 600926) receptor-type tyrosine ( 711) 992 189.1 8e-47
XP_011538297 (OMIM: 600926) PREDICTED: receptor-ty ( 711) 992 189.1 8e-47
NP_001310285 (OMIM: 600926) receptor-type tyrosine ( 718) 992 189.2 8e-47
NP_001310284 (OMIM: 600926) receptor-type tyrosine ( 720) 992 189.2 8.1e-47
XP_016871956 (OMIM: 600926) PREDICTED: receptor-ty ( 720) 992 189.2 8.1e-47
XP_016871958 (OMIM: 600926) PREDICTED: receptor-ty ( 482) 951 181.7 9.3e-45
NP_001316069 (OMIM: 179590,616001) receptor-type t (1603) 943 180.6 6.8e-44
XP_016857436 (OMIM: 179590,616001) PREDICTED: rece (1618) 943 180.6 6.9e-44
NP_001316068 (OMIM: 179590,616001) receptor-type t (1623) 943 180.6 6.9e-44
XP_016857438 (OMIM: 179590,616001) PREDICTED: rece (1623) 943 180.6 6.9e-44
XP_016857435 (OMIM: 179590,616001) PREDICTED: rece (1627) 943 180.6 6.9e-44
NP_001316066 (OMIM: 179590,616001) receptor-type t (1629) 943 180.6 6.9e-44
NP_001316067 (OMIM: 179590,616001) receptor-type t (1637) 943 180.6 6.9e-44
XP_006710864 (OMIM: 179590,616001) PREDICTED: rece (1729) 943 180.6 7.3e-44
XP_005271139 (OMIM: 179590,616001) PREDICTED: rece (1796) 943 180.6 7.5e-44
XP_016857433 (OMIM: 179590,616001) PREDICTED: rece (1800) 943 180.6 7.5e-44
XP_016857434 (OMIM: 179590,616001) PREDICTED: rece (1807) 943 180.6 7.5e-44
XP_006710863 (OMIM: 179590,616001) PREDICTED: rece (1811) 943 180.6 7.5e-44
XP_016857432 (OMIM: 179590,616001) PREDICTED: rece (1816) 943 180.6 7.6e-44
XP_006710862 (OMIM: 179590,616001) PREDICTED: rece (1820) 943 180.6 7.6e-44
NP_569707 (OMIM: 179590,616001) receptor-type tyro (1898) 943 180.6 7.8e-44
XP_006710861 (OMIM: 179590,616001) PREDICTED: rece (1902) 943 180.6 7.9e-44
NP_002831 (OMIM: 179590,616001) receptor-type tyro (1907) 943 180.6 7.9e-44
XP_005271138 (OMIM: 179590,616001) PREDICTED: rece (1909) 943 180.6 7.9e-44
XP_006710860 (OMIM: 179590,616001) PREDICTED: rece (1911) 943 180.6 7.9e-44
XP_016857431 (OMIM: 179590,616001) PREDICTED: rece (1912) 943 180.6 7.9e-44
XP_006710859 (OMIM: 179590,616001) PREDICTED: rece (1913) 943 180.6 7.9e-44
XP_005271137 (OMIM: 179590,616001) PREDICTED: rece (1918) 943 180.6 7.9e-44
XP_011540173 (OMIM: 179590,616001) PREDICTED: rece (1922) 943 180.6 7.9e-44
XP_005271136 (OMIM: 179590,616001) PREDICTED: rece (1922) 943 180.6 7.9e-44
XP_011540175 (OMIM: 179590,616001) PREDICTED: rece (1922) 943 180.6 7.9e-44
XP_011540174 (OMIM: 179590,616001) PREDICTED: rece (1922) 943 180.6 7.9e-44
XP_006710858 (OMIM: 179590,616001) PREDICTED: rece (1922) 943 180.6 7.9e-44
XP_005259667 (OMIM: 601576) PREDICTED: receptor-ty (1497) 933 178.8 2.2e-43
>>NP_563578 (OMIM: 151460,608971,609532) receptor-type t (1145 aa)
initn: 7726 init1: 7726 opt: 7726 Z-score: 7464.3 bits: 1393.0 E(85289): 0
Smith-Waterman score: 7726; 100.0% identity (100.0% similar) in 1145 aa overlap (1-1145:1-1145)
10 20 30 40 50 60
pF1KB4 MTMYLWLKLLAFGFAFLDTEVFVTGQSPTPSPTDAYLNASETTTLSPSGSAVISTTTIAT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_563 MTMYLWLKLLAFGFAFLDTEVFVTGQSPTPSPTDAYLNASETTTLSPSGSAVISTTTIAT
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB4 TPSKPTCDEKYANITVDYLYNKETKLFTAKLNVNENVECGNNTCTNNEVHNLTECKNASV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_563 TPSKPTCDEKYANITVDYLYNKETKLFTAKLNVNENVECGNNTCTNNEVHNLTECKNASV
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB4 SISHNSCTAPDKTLILDVPPGVEKFQLHDCTQVEKADTTICLKWKNIETFTCDTQNITYR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_563 SISHNSCTAPDKTLILDVPPGVEKFQLHDCTQVEKADTTICLKWKNIETFTCDTQNITYR
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB4 FQCGNMIFDNKEIKLENLEPEHEYKCDSEILYNNHKFTNASKIIKTDFGSPGEPQIIFCR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_563 FQCGNMIFDNKEIKLENLEPEHEYKCDSEILYNNHKFTNASKIIKTDFGSPGEPQIIFCR
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB4 SEAAHQGVITWNPPQRSFHNFTLCYIKETEKDCLNLDKNLIKYDLQNLKPYTKYVLSLHA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_563 SEAAHQGVITWNPPQRSFHNFTLCYIKETEKDCLNLDKNLIKYDLQNLKPYTKYVLSLHA
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB4 YIIAKVQRNGSAAMCHFTTKSAPPSQVWNMTVSMTSDNSMHVKCRPPRDRNGPHERYHLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_563 YIIAKVQRNGSAAMCHFTTKSAPPSQVWNMTVSMTSDNSMHVKCRPPRDRNGPHERYHLE
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB4 VEAGNTLVRNESHKNCDFRVKDLQYSTDYTFKAYFHNGDYPGEPFILHHSTSYNSKALIA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_563 VEAGNTLVRNESHKNCDFRVKDLQYSTDYTFKAYFHNGDYPGEPFILHHSTSYNSKALIA
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB4 FLAFLIIVTSIALLVVLYKIYDLHKKRSCNLDEQQELVERDDEKQLMNVEPIHADILLET
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_563 FLAFLIIVTSIALLVVLYKIYDLHKKRSCNLDEQQELVERDDEKQLMNVEPIHADILLET
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB4 YKRKIADEGRLFLAEFQSIPRVFSKFPIKEARKPFNQNKNRYVDILPYDYNRVELSEING
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_563 YKRKIADEGRLFLAEFQSIPRVFSKFPIKEARKPFNQNKNRYVDILPYDYNRVELSEING
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB4 DAGSNYINASYIDGFKEPRKYIAAQGPRDETVDDFWRMIWEQKATVIVMVTRCEEGNRNK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_563 DAGSNYINASYIDGFKEPRKYIAAQGPRDETVDDFWRMIWEQKATVIVMVTRCEEGNRNK
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB4 CAEYWPSMEEGTRAFGDVVVKINQHKRCPDYIIQKLNIVNKKEKATGREVTHIQFTSWPD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_563 CAEYWPSMEEGTRAFGDVVVKINQHKRCPDYIIQKLNIVNKKEKATGREVTHIQFTSWPD
610 620 630 640 650 660
670 680 690 700 710 720
pF1KB4 HGVPEDPHLLLKLRRRVNAFSNFFSGPIVVHCSAGVGRTGTYIGIDAMLEGLEAENKVDV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_563 HGVPEDPHLLLKLRRRVNAFSNFFSGPIVVHCSAGVGRTGTYIGIDAMLEGLEAENKVDV
670 680 690 700 710 720
730 740 750 760 770 780
pF1KB4 YGYVVKLRRQRCLMVQVEAQYILIHQALVEYNQFGETEVNLSELHPYLHNMKKRDPPSEP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_563 YGYVVKLRRQRCLMVQVEAQYILIHQALVEYNQFGETEVNLSELHPYLHNMKKRDPPSEP
730 740 750 760 770 780
790 800 810 820 830 840
pF1KB4 SPLEAEFQRLPSYRSWRTQHIGNQEENKSKNRNSNVIPYDYNRVPLKHELEMSKESEHDS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_563 SPLEAEFQRLPSYRSWRTQHIGNQEENKSKNRNSNVIPYDYNRVPLKHELEMSKESEHDS
790 800 810 820 830 840
850 860 870 880 890 900
pF1KB4 DESSDDDSDSEEPSKYINASFIMSYWKPEVMIAAQGPLKETIGDFWQMIFQRKVKVIVML
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_563 DESSDDDSDSEEPSKYINASFIMSYWKPEVMIAAQGPLKETIGDFWQMIFQRKVKVIVML
850 860 870 880 890 900
910 920 930 940 950 960
pF1KB4 TELKHGDQEICAQYWGEGKQTYGDIEVDLKDTDKSSTYTLRVFELRHSKRKDSRTVYQYQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_563 TELKHGDQEICAQYWGEGKQTYGDIEVDLKDTDKSSTYTLRVFELRHSKRKDSRTVYQYQ
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KB4 YTNWSVEQLPAEPKELISMIQVVKQKLPQKNSSEGNKHHKSTPLLIHCRDGSQQTGIFCA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_563 YTNWSVEQLPAEPKELISMIQVVKQKLPQKNSSEGNKHHKSTPLLIHCRDGSQQTGIFCA
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KB4 LLNLLESAETEEVVDIFQVVKALRKARPGMVSTFEQYQFLYDVIASTYPAQNGQVKKNNH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_563 LLNLLESAETEEVVDIFQVVKALRKARPGMVSTFEQYQFLYDVIASTYPAQNGQVKKNNH
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KB4 QEDKIEFDNEVDKVKQDANCVNPLGAPEKLPEAKEQAEGSEPTSGTEGPEHSVNGPASPA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_563 QEDKIEFDNEVDKVKQDANCVNPLGAPEKLPEAKEQAEGSEPTSGTEGPEHSVNGPASPA
1090 1100 1110 1120 1130 1140
pF1KB4 LNQGS
:::::
NP_563 LNQGS
>>XP_006711537 (OMIM: 151460,608971,609532) PREDICTED: r (1192 aa)
initn: 7506 init1: 7506 opt: 7515 Z-score: 7260.2 bits: 1355.3 E(85289): 0
Smith-Waterman score: 7520; 96.0% identity (96.0% similar) in 1177 aa overlap (16-1145:16-1192)
10 20 30
pF1KB4 MTMYLWLKLLAFGFAFLDTEVFVTGQSPTPSPT---------------------------
::::::::::::::::::
XP_006 MTMYLWLKLLAFGFAFLDTEVFVTGQSPTPSPTGVSSVQTPHLPTHADSQTPSAGTDTQT
10 20 30 40 50 60
40 50 60 70
pF1KB4 --------------------DAYLNASETTTLSPSGSAVISTTTIATTPSKPTCDEKYAN
::::::::::::::::::::::::::::::::::::::::
XP_006 FSGSAANAKLNPTPGSNAISDAYLNASETTTLSPSGSAVISTTTIATTPSKPTCDEKYAN
70 80 90 100 110 120
80 90 100 110 120 130
pF1KB4 ITVDYLYNKETKLFTAKLNVNENVECGNNTCTNNEVHNLTECKNASVSISHNSCTAPDKT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 ITVDYLYNKETKLFTAKLNVNENVECGNNTCTNNEVHNLTECKNASVSISHNSCTAPDKT
130 140 150 160 170 180
140 150 160 170 180 190
pF1KB4 LILDVPPGVEKFQLHDCTQVEKADTTICLKWKNIETFTCDTQNITYRFQCGNMIFDNKEI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LILDVPPGVEKFQLHDCTQVEKADTTICLKWKNIETFTCDTQNITYRFQCGNMIFDNKEI
190 200 210 220 230 240
200 210 220 230 240 250
pF1KB4 KLENLEPEHEYKCDSEILYNNHKFTNASKIIKTDFGSPGEPQIIFCRSEAAHQGVITWNP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 KLENLEPEHEYKCDSEILYNNHKFTNASKIIKTDFGSPGEPQIIFCRSEAAHQGVITWNP
250 260 270 280 290 300
260 270 280 290 300 310
pF1KB4 PQRSFHNFTLCYIKETEKDCLNLDKNLIKYDLQNLKPYTKYVLSLHAYIIAKVQRNGSAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 PQRSFHNFTLCYIKETEKDCLNLDKNLIKYDLQNLKPYTKYVLSLHAYIIAKVQRNGSAA
310 320 330 340 350 360
320 330 340 350 360 370
pF1KB4 MCHFTTKSAPPSQVWNMTVSMTSDNSMHVKCRPPRDRNGPHERYHLEVEAGNTLVRNESH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 MCHFTTKSAPPSQVWNMTVSMTSDNSMHVKCRPPRDRNGPHERYHLEVEAGNTLVRNESH
370 380 390 400 410 420
380 390 400 410 420 430
pF1KB4 KNCDFRVKDLQYSTDYTFKAYFHNGDYPGEPFILHHSTSYNSKALIAFLAFLIIVTSIAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 KNCDFRVKDLQYSTDYTFKAYFHNGDYPGEPFILHHSTSYNSKALIAFLAFLIIVTSIAL
430 440 450 460 470 480
440 450 460 470 480 490
pF1KB4 LVVLYKIYDLHKKRSCNLDEQQELVERDDEKQLMNVEPIHADILLETYKRKIADEGRLFL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LVVLYKIYDLHKKRSCNLDEQQELVERDDEKQLMNVEPIHADILLETYKRKIADEGRLFL
490 500 510 520 530 540
500 510 520 530 540 550
pF1KB4 AEFQSIPRVFSKFPIKEARKPFNQNKNRYVDILPYDYNRVELSEINGDAGSNYINASYID
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 AEFQSIPRVFSKFPIKEARKPFNQNKNRYVDILPYDYNRVELSEINGDAGSNYINASYID
550 560 570 580 590 600
560 570 580 590 600 610
pF1KB4 GFKEPRKYIAAQGPRDETVDDFWRMIWEQKATVIVMVTRCEEGNRNKCAEYWPSMEEGTR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 GFKEPRKYIAAQGPRDETVDDFWRMIWEQKATVIVMVTRCEEGNRNKCAEYWPSMEEGTR
610 620 630 640 650 660
620 630 640 650 660 670
pF1KB4 AFGDVVVKINQHKRCPDYIIQKLNIVNKKEKATGREVTHIQFTSWPDHGVPEDPHLLLKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 AFGDVVVKINQHKRCPDYIIQKLNIVNKKEKATGREVTHIQFTSWPDHGVPEDPHLLLKL
670 680 690 700 710 720
680 690 700 710 720 730
pF1KB4 RRRVNAFSNFFSGPIVVHCSAGVGRTGTYIGIDAMLEGLEAENKVDVYGYVVKLRRQRCL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 RRRVNAFSNFFSGPIVVHCSAGVGRTGTYIGIDAMLEGLEAENKVDVYGYVVKLRRQRCL
730 740 750 760 770 780
740 750 760 770 780 790
pF1KB4 MVQVEAQYILIHQALVEYNQFGETEVNLSELHPYLHNMKKRDPPSEPSPLEAEFQRLPSY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 MVQVEAQYILIHQALVEYNQFGETEVNLSELHPYLHNMKKRDPPSEPSPLEAEFQRLPSY
790 800 810 820 830 840
800 810 820 830 840 850
pF1KB4 RSWRTQHIGNQEENKSKNRNSNVIPYDYNRVPLKHELEMSKESEHDSDESSDDDSDSEEP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 RSWRTQHIGNQEENKSKNRNSNVIPYDYNRVPLKHELEMSKESEHDSDESSDDDSDSEEP
850 860 870 880 890 900
860 870 880 890 900 910
pF1KB4 SKYINASFIMSYWKPEVMIAAQGPLKETIGDFWQMIFQRKVKVIVMLTELKHGDQEICAQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 SKYINASFIMSYWKPEVMIAAQGPLKETIGDFWQMIFQRKVKVIVMLTELKHGDQEICAQ
910 920 930 940 950 960
920 930 940 950 960 970
pF1KB4 YWGEGKQTYGDIEVDLKDTDKSSTYTLRVFELRHSKRKDSRTVYQYQYTNWSVEQLPAEP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 YWGEGKQTYGDIEVDLKDTDKSSTYTLRVFELRHSKRKDSRTVYQYQYTNWSVEQLPAEP
970 980 990 1000 1010 1020
980 990 1000 1010 1020 1030
pF1KB4 KELISMIQVVKQKLPQKNSSEGNKHHKSTPLLIHCRDGSQQTGIFCALLNLLESAETEEV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 KELISMIQVVKQKLPQKNSSEGNKHHKSTPLLIHCRDGSQQTGIFCALLNLLESAETEEV
1030 1040 1050 1060 1070 1080
1040 1050 1060 1070 1080 1090
pF1KB4 VDIFQVVKALRKARPGMVSTFEQYQFLYDVIASTYPAQNGQVKKNNHQEDKIEFDNEVDK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 VDIFQVVKALRKARPGMVSTFEQYQFLYDVIASTYPAQNGQVKKNNHQEDKIEFDNEVDK
1090 1100 1110 1120 1130 1140
1100 1110 1120 1130 1140
pF1KB4 VKQDANCVNPLGAPEKLPEAKEQAEGSEPTSGTEGPEHSVNGPASPALNQGS
::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 VKQDANCVNPLGAPEKLPEAKEQAEGSEPTSGTEGPEHSVNGPASPALNQGS
1150 1160 1170 1180 1190
>>XP_006711535 (OMIM: 151460,608971,609532) PREDICTED: r (1258 aa)
initn: 7506 init1: 7506 opt: 7515 Z-score: 7259.9 bits: 1355.3 E(85289): 0
Smith-Waterman score: 7515; 99.4% identity (99.6% similar) in 1122 aa overlap (27-1145:137-1258)
10 20 30 40 50
pF1KB4 MTMYLWLKLLAFGFAFLDTEVFVTGQSPTPSP---TDAYLNASETTTLSPSGSAVI
.:::. .::::::::::::::::::::
XP_006 PHLPTHADSQTPSAGTDTQTFSGSAANAKLNPTPGSNAISDAYLNASETTTLSPSGSAVI
110 120 130 140 150 160
60 70 80 90 100 110
pF1KB4 STTTIATTPSKPTCDEKYANITVDYLYNKETKLFTAKLNVNENVECGNNTCTNNEVHNLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 STTTIATTPSKPTCDEKYANITVDYLYNKETKLFTAKLNVNENVECGNNTCTNNEVHNLT
170 180 190 200 210 220
120 130 140 150 160 170
pF1KB4 ECKNASVSISHNSCTAPDKTLILDVPPGVEKFQLHDCTQVEKADTTICLKWKNIETFTCD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 ECKNASVSISHNSCTAPDKTLILDVPPGVEKFQLHDCTQVEKADTTICLKWKNIETFTCD
230 240 250 260 270 280
180 190 200 210 220 230
pF1KB4 TQNITYRFQCGNMIFDNKEIKLENLEPEHEYKCDSEILYNNHKFTNASKIIKTDFGSPGE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 TQNITYRFQCGNMIFDNKEIKLENLEPEHEYKCDSEILYNNHKFTNASKIIKTDFGSPGE
290 300 310 320 330 340
240 250 260 270 280 290
pF1KB4 PQIIFCRSEAAHQGVITWNPPQRSFHNFTLCYIKETEKDCLNLDKNLIKYDLQNLKPYTK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 PQIIFCRSEAAHQGVITWNPPQRSFHNFTLCYIKETEKDCLNLDKNLIKYDLQNLKPYTK
350 360 370 380 390 400
300 310 320 330 340 350
pF1KB4 YVLSLHAYIIAKVQRNGSAAMCHFTTKSAPPSQVWNMTVSMTSDNSMHVKCRPPRDRNGP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 YVLSLHAYIIAKVQRNGSAAMCHFTTKSAPPSQVWNMTVSMTSDNSMHVKCRPPRDRNGP
410 420 430 440 450 460
360 370 380 390 400 410
pF1KB4 HERYHLEVEAGNTLVRNESHKNCDFRVKDLQYSTDYTFKAYFHNGDYPGEPFILHHSTSY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 HERYHLEVEAGNTLVRNESHKNCDFRVKDLQYSTDYTFKAYFHNGDYPGEPFILHHSTSY
470 480 490 500 510 520
420 430 440 450 460 470
pF1KB4 NSKALIAFLAFLIIVTSIALLVVLYKIYDLHKKRSCNLDEQQELVERDDEKQLMNVEPIH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 NSKALIAFLAFLIIVTSIALLVVLYKIYDLHKKRSCNLDEQQELVERDDEKQLMNVEPIH
530 540 550 560 570 580
480 490 500 510 520 530
pF1KB4 ADILLETYKRKIADEGRLFLAEFQSIPRVFSKFPIKEARKPFNQNKNRYVDILPYDYNRV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 ADILLETYKRKIADEGRLFLAEFQSIPRVFSKFPIKEARKPFNQNKNRYVDILPYDYNRV
590 600 610 620 630 640
540 550 560 570 580 590
pF1KB4 ELSEINGDAGSNYINASYIDGFKEPRKYIAAQGPRDETVDDFWRMIWEQKATVIVMVTRC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 ELSEINGDAGSNYINASYIDGFKEPRKYIAAQGPRDETVDDFWRMIWEQKATVIVMVTRC
650 660 670 680 690 700
600 610 620 630 640 650
pF1KB4 EEGNRNKCAEYWPSMEEGTRAFGDVVVKINQHKRCPDYIIQKLNIVNKKEKATGREVTHI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 EEGNRNKCAEYWPSMEEGTRAFGDVVVKINQHKRCPDYIIQKLNIVNKKEKATGREVTHI
710 720 730 740 750 760
660 670 680 690 700 710
pF1KB4 QFTSWPDHGVPEDPHLLLKLRRRVNAFSNFFSGPIVVHCSAGVGRTGTYIGIDAMLEGLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 QFTSWPDHGVPEDPHLLLKLRRRVNAFSNFFSGPIVVHCSAGVGRTGTYIGIDAMLEGLE
770 780 790 800 810 820
720 730 740 750 760 770
pF1KB4 AENKVDVYGYVVKLRRQRCLMVQVEAQYILIHQALVEYNQFGETEVNLSELHPYLHNMKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 AENKVDVYGYVVKLRRQRCLMVQVEAQYILIHQALVEYNQFGETEVNLSELHPYLHNMKK
830 840 850 860 870 880
780 790 800 810 820 830
pF1KB4 RDPPSEPSPLEAEFQRLPSYRSWRTQHIGNQEENKSKNRNSNVIPYDYNRVPLKHELEMS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 RDPPSEPSPLEAEFQRLPSYRSWRTQHIGNQEENKSKNRNSNVIPYDYNRVPLKHELEMS
890 900 910 920 930 940
840 850 860 870 880 890
pF1KB4 KESEHDSDESSDDDSDSEEPSKYINASFIMSYWKPEVMIAAQGPLKETIGDFWQMIFQRK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 KESEHDSDESSDDDSDSEEPSKYINASFIMSYWKPEVMIAAQGPLKETIGDFWQMIFQRK
950 960 970 980 990 1000
900 910 920 930 940 950
pF1KB4 VKVIVMLTELKHGDQEICAQYWGEGKQTYGDIEVDLKDTDKSSTYTLRVFELRHSKRKDS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 VKVIVMLTELKHGDQEICAQYWGEGKQTYGDIEVDLKDTDKSSTYTLRVFELRHSKRKDS
1010 1020 1030 1040 1050 1060
960 970 980 990 1000 1010
pF1KB4 RTVYQYQYTNWSVEQLPAEPKELISMIQVVKQKLPQKNSSEGNKHHKSTPLLIHCRDGSQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 RTVYQYQYTNWSVEQLPAEPKELISMIQVVKQKLPQKNSSEGNKHHKSTPLLIHCRDGSQ
1070 1080 1090 1100 1110 1120
1020 1030 1040 1050 1060 1070
pF1KB4 QTGIFCALLNLLESAETEEVVDIFQVVKALRKARPGMVSTFEQYQFLYDVIASTYPAQNG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 QTGIFCALLNLLESAETEEVVDIFQVVKALRKARPGMVSTFEQYQFLYDVIASTYPAQNG
1130 1140 1150 1160 1170 1180
1080 1090 1100 1110 1120 1130
pF1KB4 QVKKNNHQEDKIEFDNEVDKVKQDANCVNPLGAPEKLPEAKEQAEGSEPTSGTEGPEHSV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 QVKKNNHQEDKIEFDNEVDKVKQDANCVNPLGAPEKLPEAKEQAEGSEPTSGTEGPEHSV
1190 1200 1210 1220 1230 1240
1140
pF1KB4 NGPASPALNQGS
::::::::::::
XP_006 NGPASPALNQGS
1250
>--
initn: 288 init1: 222 opt: 234 Z-score: 225.6 bits: 53.8 E(85289): 7.9e-06
Smith-Waterman score: 234; 63.5% identity (79.4% similar) in 63 aa overlap (1-63:1-60)
10 20 30 40 50 60
pF1KB4 MTMYLWLKLLAFGFAFLDTEVFVTGQSPTPSPTDAYLNASETTTLSPSGSAVISTTTIAT
::::::::::::::::::::::::::::::::: :.... .. : .: . : : :
XP_006 MTMYLWLKLLAFGFAFLDTEVFVTGQSPTPSPTG--LTTAKMPSV-PLSSDPLPTHTTAF
10 20 30 40 50
70 80 90 100 110 120
pF1KB4 TPSKPTCDEKYANITVDYLYNKETKLFTAKLNVNENVECGNNTCTNNEVHNLTECKNASV
.:.
XP_006 SPASTFERENDFSETTTSLSPDNTSTQVSPDSLDNASAFNTTGVSSVQTPHLPTHADSQT
60 70 80 90 100 110
>>XP_006711536 (OMIM: 151460,608971,609532) PREDICTED: r (1240 aa)
initn: 7510 init1: 7510 opt: 7510 Z-score: 7255.1 bits: 1354.5 E(85289): 0
Smith-Waterman score: 7510; 99.6% identity (99.8% similar) in 1117 aa overlap (29-1145:124-1240)
10 20 30 40 50
pF1KB4 MTMYLWLKLLAFGFAFLDTEVFVTGQSPTPSPTDAYLNASETTTLSPSGSAVISTTTI
: . .:::::::::::::::::::::::::
XP_006 TDPVSPLTTTLSLAHHSSAALPARTSNTTITANTSDAYLNASETTTLSPSGSAVISTTTI
100 110 120 130 140 150
60 70 80 90 100 110
pF1KB4 ATTPSKPTCDEKYANITVDYLYNKETKLFTAKLNVNENVECGNNTCTNNEVHNLTECKNA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 ATTPSKPTCDEKYANITVDYLYNKETKLFTAKLNVNENVECGNNTCTNNEVHNLTECKNA
160 170 180 190 200 210
120 130 140 150 160 170
pF1KB4 SVSISHNSCTAPDKTLILDVPPGVEKFQLHDCTQVEKADTTICLKWKNIETFTCDTQNIT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 SVSISHNSCTAPDKTLILDVPPGVEKFQLHDCTQVEKADTTICLKWKNIETFTCDTQNIT
220 230 240 250 260 270
180 190 200 210 220 230
pF1KB4 YRFQCGNMIFDNKEIKLENLEPEHEYKCDSEILYNNHKFTNASKIIKTDFGSPGEPQIIF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 YRFQCGNMIFDNKEIKLENLEPEHEYKCDSEILYNNHKFTNASKIIKTDFGSPGEPQIIF
280 290 300 310 320 330
240 250 260 270 280 290
pF1KB4 CRSEAAHQGVITWNPPQRSFHNFTLCYIKETEKDCLNLDKNLIKYDLQNLKPYTKYVLSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 CRSEAAHQGVITWNPPQRSFHNFTLCYIKETEKDCLNLDKNLIKYDLQNLKPYTKYVLSL
340 350 360 370 380 390
300 310 320 330 340 350
pF1KB4 HAYIIAKVQRNGSAAMCHFTTKSAPPSQVWNMTVSMTSDNSMHVKCRPPRDRNGPHERYH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 HAYIIAKVQRNGSAAMCHFTTKSAPPSQVWNMTVSMTSDNSMHVKCRPPRDRNGPHERYH
400 410 420 430 440 450
360 370 380 390 400 410
pF1KB4 LEVEAGNTLVRNESHKNCDFRVKDLQYSTDYTFKAYFHNGDYPGEPFILHHSTSYNSKAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LEVEAGNTLVRNESHKNCDFRVKDLQYSTDYTFKAYFHNGDYPGEPFILHHSTSYNSKAL
460 470 480 490 500 510
420 430 440 450 460 470
pF1KB4 IAFLAFLIIVTSIALLVVLYKIYDLHKKRSCNLDEQQELVERDDEKQLMNVEPIHADILL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 IAFLAFLIIVTSIALLVVLYKIYDLHKKRSCNLDEQQELVERDDEKQLMNVEPIHADILL
520 530 540 550 560 570
480 490 500 510 520 530
pF1KB4 ETYKRKIADEGRLFLAEFQSIPRVFSKFPIKEARKPFNQNKNRYVDILPYDYNRVELSEI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 ETYKRKIADEGRLFLAEFQSIPRVFSKFPIKEARKPFNQNKNRYVDILPYDYNRVELSEI
580 590 600 610 620 630
540 550 560 570 580 590
pF1KB4 NGDAGSNYINASYIDGFKEPRKYIAAQGPRDETVDDFWRMIWEQKATVIVMVTRCEEGNR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 NGDAGSNYINASYIDGFKEPRKYIAAQGPRDETVDDFWRMIWEQKATVIVMVTRCEEGNR
640 650 660 670 680 690
600 610 620 630 640 650
pF1KB4 NKCAEYWPSMEEGTRAFGDVVVKINQHKRCPDYIIQKLNIVNKKEKATGREVTHIQFTSW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 NKCAEYWPSMEEGTRAFGDVVVKINQHKRCPDYIIQKLNIVNKKEKATGREVTHIQFTSW
700 710 720 730 740 750
660 670 680 690 700 710
pF1KB4 PDHGVPEDPHLLLKLRRRVNAFSNFFSGPIVVHCSAGVGRTGTYIGIDAMLEGLEAENKV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 PDHGVPEDPHLLLKLRRRVNAFSNFFSGPIVVHCSAGVGRTGTYIGIDAMLEGLEAENKV
760 770 780 790 800 810
720 730 740 750 760 770
pF1KB4 DVYGYVVKLRRQRCLMVQVEAQYILIHQALVEYNQFGETEVNLSELHPYLHNMKKRDPPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 DVYGYVVKLRRQRCLMVQVEAQYILIHQALVEYNQFGETEVNLSELHPYLHNMKKRDPPS
820 830 840 850 860 870
780 790 800 810 820 830
pF1KB4 EPSPLEAEFQRLPSYRSWRTQHIGNQEENKSKNRNSNVIPYDYNRVPLKHELEMSKESEH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 EPSPLEAEFQRLPSYRSWRTQHIGNQEENKSKNRNSNVIPYDYNRVPLKHELEMSKESEH
880 890 900 910 920 930
840 850 860 870 880 890
pF1KB4 DSDESSDDDSDSEEPSKYINASFIMSYWKPEVMIAAQGPLKETIGDFWQMIFQRKVKVIV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 DSDESSDDDSDSEEPSKYINASFIMSYWKPEVMIAAQGPLKETIGDFWQMIFQRKVKVIV
940 950 960 970 980 990
900 910 920 930 940 950
pF1KB4 MLTELKHGDQEICAQYWGEGKQTYGDIEVDLKDTDKSSTYTLRVFELRHSKRKDSRTVYQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 MLTELKHGDQEICAQYWGEGKQTYGDIEVDLKDTDKSSTYTLRVFELRHSKRKDSRTVYQ
1000 1010 1020 1030 1040 1050
960 970 980 990 1000 1010
pF1KB4 YQYTNWSVEQLPAEPKELISMIQVVKQKLPQKNSSEGNKHHKSTPLLIHCRDGSQQTGIF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 YQYTNWSVEQLPAEPKELISMIQVVKQKLPQKNSSEGNKHHKSTPLLIHCRDGSQQTGIF
1060 1070 1080 1090 1100 1110
1020 1030 1040 1050 1060 1070
pF1KB4 CALLNLLESAETEEVVDIFQVVKALRKARPGMVSTFEQYQFLYDVIASTYPAQNGQVKKN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 CALLNLLESAETEEVVDIFQVVKALRKARPGMVSTFEQYQFLYDVIASTYPAQNGQVKKN
1120 1130 1140 1150 1160 1170
1080 1090 1100 1110 1120 1130
pF1KB4 NHQEDKIEFDNEVDKVKQDANCVNPLGAPEKLPEAKEQAEGSEPTSGTEGPEHSVNGPAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 NHQEDKIEFDNEVDKVKQDANCVNPLGAPEKLPEAKEQAEGSEPTSGTEGPEHSVNGPAS
1180 1190 1200 1210 1220 1230
1140
pF1KB4 PALNQGS
:::::::
XP_006 PALNQGS
1240
>--
initn: 269 init1: 222 opt: 222 Z-score: 214.1 bits: 51.6 E(85289): 3.5e-05
Smith-Waterman score: 222; 100.0% identity (100.0% similar) in 33 aa overlap (1-33:1-33)
10 20 30 40 50 60
pF1KB4 MTMYLWLKLLAFGFAFLDTEVFVTGQSPTPSPTDAYLNASETTTLSPSGSAVISTTTIAT
:::::::::::::::::::::::::::::::::
XP_006 MTMYLWLKLLAFGFAFLDTEVFVTGQSPTPSPTGVSSVQTPHLPTHADSQTPSAGTDTQT
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB4 TPSKPTCDEKYANITVDYLYNKETKLFTAKLNVNENVECGNNTCTNNEVHNLTECKNASV
XP_006 FSGSAANAKLNPTPGSNAISDVPGERSTASTFPTDPVSPLTTTLSLAHHSSAALPARTSN
70 80 90 100 110 120
>>NP_002829 (OMIM: 151460,608971,609532) receptor-type t (1306 aa)
initn: 7510 init1: 7510 opt: 7510 Z-score: 7254.8 bits: 1354.5 E(85289): 0
Smith-Waterman score: 7510; 99.6% identity (99.8% similar) in 1117 aa overlap (29-1145:190-1306)
10 20 30 40 50
pF1KB4 MTMYLWLKLLAFGFAFLDTEVFVTGQSPTPSPTDAYLNASETTTLSPSGSAVISTTTI
: . .:::::::::::::::::::::::::
NP_002 TDPVSPLTTTLSLAHHSSAALPARTSNTTITANTSDAYLNASETTTLSPSGSAVISTTTI
160 170 180 190 200 210
60 70 80 90 100 110
pF1KB4 ATTPSKPTCDEKYANITVDYLYNKETKLFTAKLNVNENVECGNNTCTNNEVHNLTECKNA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 ATTPSKPTCDEKYANITVDYLYNKETKLFTAKLNVNENVECGNNTCTNNEVHNLTECKNA
220 230 240 250 260 270
120 130 140 150 160 170
pF1KB4 SVSISHNSCTAPDKTLILDVPPGVEKFQLHDCTQVEKADTTICLKWKNIETFTCDTQNIT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 SVSISHNSCTAPDKTLILDVPPGVEKFQLHDCTQVEKADTTICLKWKNIETFTCDTQNIT
280 290 300 310 320 330
180 190 200 210 220 230
pF1KB4 YRFQCGNMIFDNKEIKLENLEPEHEYKCDSEILYNNHKFTNASKIIKTDFGSPGEPQIIF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 YRFQCGNMIFDNKEIKLENLEPEHEYKCDSEILYNNHKFTNASKIIKTDFGSPGEPQIIF
340 350 360 370 380 390
240 250 260 270 280 290
pF1KB4 CRSEAAHQGVITWNPPQRSFHNFTLCYIKETEKDCLNLDKNLIKYDLQNLKPYTKYVLSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 CRSEAAHQGVITWNPPQRSFHNFTLCYIKETEKDCLNLDKNLIKYDLQNLKPYTKYVLSL
400 410 420 430 440 450
300 310 320 330 340 350
pF1KB4 HAYIIAKVQRNGSAAMCHFTTKSAPPSQVWNMTVSMTSDNSMHVKCRPPRDRNGPHERYH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 HAYIIAKVQRNGSAAMCHFTTKSAPPSQVWNMTVSMTSDNSMHVKCRPPRDRNGPHERYH
460 470 480 490 500 510
360 370 380 390 400 410
pF1KB4 LEVEAGNTLVRNESHKNCDFRVKDLQYSTDYTFKAYFHNGDYPGEPFILHHSTSYNSKAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 LEVEAGNTLVRNESHKNCDFRVKDLQYSTDYTFKAYFHNGDYPGEPFILHHSTSYNSKAL
520 530 540 550 560 570
420 430 440 450 460 470
pF1KB4 IAFLAFLIIVTSIALLVVLYKIYDLHKKRSCNLDEQQELVERDDEKQLMNVEPIHADILL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 IAFLAFLIIVTSIALLVVLYKIYDLHKKRSCNLDEQQELVERDDEKQLMNVEPIHADILL
580 590 600 610 620 630
480 490 500 510 520 530
pF1KB4 ETYKRKIADEGRLFLAEFQSIPRVFSKFPIKEARKPFNQNKNRYVDILPYDYNRVELSEI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 ETYKRKIADEGRLFLAEFQSIPRVFSKFPIKEARKPFNQNKNRYVDILPYDYNRVELSEI
640 650 660 670 680 690
540 550 560 570 580 590
pF1KB4 NGDAGSNYINASYIDGFKEPRKYIAAQGPRDETVDDFWRMIWEQKATVIVMVTRCEEGNR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 NGDAGSNYINASYIDGFKEPRKYIAAQGPRDETVDDFWRMIWEQKATVIVMVTRCEEGNR
700 710 720 730 740 750
600 610 620 630 640 650
pF1KB4 NKCAEYWPSMEEGTRAFGDVVVKINQHKRCPDYIIQKLNIVNKKEKATGREVTHIQFTSW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 NKCAEYWPSMEEGTRAFGDVVVKINQHKRCPDYIIQKLNIVNKKEKATGREVTHIQFTSW
760 770 780 790 800 810
660 670 680 690 700 710
pF1KB4 PDHGVPEDPHLLLKLRRRVNAFSNFFSGPIVVHCSAGVGRTGTYIGIDAMLEGLEAENKV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 PDHGVPEDPHLLLKLRRRVNAFSNFFSGPIVVHCSAGVGRTGTYIGIDAMLEGLEAENKV
820 830 840 850 860 870
720 730 740 750 760 770
pF1KB4 DVYGYVVKLRRQRCLMVQVEAQYILIHQALVEYNQFGETEVNLSELHPYLHNMKKRDPPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 DVYGYVVKLRRQRCLMVQVEAQYILIHQALVEYNQFGETEVNLSELHPYLHNMKKRDPPS
880 890 900 910 920 930
780 790 800 810 820 830
pF1KB4 EPSPLEAEFQRLPSYRSWRTQHIGNQEENKSKNRNSNVIPYDYNRVPLKHELEMSKESEH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 EPSPLEAEFQRLPSYRSWRTQHIGNQEENKSKNRNSNVIPYDYNRVPLKHELEMSKESEH
940 950 960 970 980 990
840 850 860 870 880 890
pF1KB4 DSDESSDDDSDSEEPSKYINASFIMSYWKPEVMIAAQGPLKETIGDFWQMIFQRKVKVIV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 DSDESSDDDSDSEEPSKYINASFIMSYWKPEVMIAAQGPLKETIGDFWQMIFQRKVKVIV
1000 1010 1020 1030 1040 1050
900 910 920 930 940 950
pF1KB4 MLTELKHGDQEICAQYWGEGKQTYGDIEVDLKDTDKSSTYTLRVFELRHSKRKDSRTVYQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 MLTELKHGDQEICAQYWGEGKQTYGDIEVDLKDTDKSSTYTLRVFELRHSKRKDSRTVYQ
1060 1070 1080 1090 1100 1110
960 970 980 990 1000 1010
pF1KB4 YQYTNWSVEQLPAEPKELISMIQVVKQKLPQKNSSEGNKHHKSTPLLIHCRDGSQQTGIF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 YQYTNWSVEQLPAEPKELISMIQVVKQKLPQKNSSEGNKHHKSTPLLIHCRDGSQQTGIF
1120 1130 1140 1150 1160 1170
1020 1030 1040 1050 1060 1070
pF1KB4 CALLNLLESAETEEVVDIFQVVKALRKARPGMVSTFEQYQFLYDVIASTYPAQNGQVKKN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 CALLNLLESAETEEVVDIFQVVKALRKARPGMVSTFEQYQFLYDVIASTYPAQNGQVKKN
1180 1190 1200 1210 1220 1230
1080 1090 1100 1110 1120 1130
pF1KB4 NHQEDKIEFDNEVDKVKQDANCVNPLGAPEKLPEAKEQAEGSEPTSGTEGPEHSVNGPAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 NHQEDKIEFDNEVDKVKQDANCVNPLGAPEKLPEAKEQAEGSEPTSGTEGPEHSVNGPAS
1240 1250 1260 1270 1280 1290
1140
pF1KB4 PALNQGS
:::::::
NP_002 PALNQGS
1300
>--
initn: 297 init1: 222 opt: 234 Z-score: 225.4 bits: 53.8 E(85289): 8.2e-06
Smith-Waterman score: 234; 63.5% identity (79.4% similar) in 63 aa overlap (1-63:1-60)
10 20 30 40 50 60
pF1KB4 MTMYLWLKLLAFGFAFLDTEVFVTGQSPTPSPTDAYLNASETTTLSPSGSAVISTTTIAT
::::::::::::::::::::::::::::::::: :.... .. : .: . : : :
NP_002 MTMYLWLKLLAFGFAFLDTEVFVTGQSPTPSPTG--LTTAKMPSV-PLSSDPLPTHTTAF
10 20 30 40 50
70 80 90 100 110 120
pF1KB4 TPSKPTCDEKYANITVDYLYNKETKLFTAKLNVNENVECGNNTCTNNEVHNLTECKNASV
.:.
NP_002 SPASTFERENDFSETTTSLSPDNTSTQVSPDSLDNASAFNTTGVSSVQTPHLPTHADSQT
60 70 80 90 100 110
>>NP_543031 (OMIM: 176884) receptor-type tyrosine-protei (793 aa)
initn: 1453 init1: 490 opt: 1069 Z-score: 1035.3 bits: 202.9 E(85289): 6.3e-51
Smith-Waterman score: 1607; 39.9% identity (69.6% similar) in 667 aa overlap (418-1064:147-779)
390 400 410 420 430 440
pF1KB4 DYTFKAYFHNGDYPGEPFILHHSTSYNSKALIAFLAFLIIVTSIALLVVL-YKIYD----
..:. ..:.:: : .: .: .: :
NP_543 RTEPWEGNSSTAATTPETFPPSDETPIIAVMVALSSLLVIVFIIIVLYMLRFKKYKQAGS
120 130 140 150 160 170
450 460 470 480 490
pF1KB4 ------LHKKRSCNLDEQQ-ELVERDDEKQLMNVEPIHADILLETYKRKIADEGRLFLAE
: . :. ... :. :. :. . . :. .: : : .:..::...:: :
NP_543 HSNSFRLSNGRTEDVEPQSVPLLARSPSTN-RKYPPLPVDKLEEEINRRMADDNKLFREE
180 190 200 210 220 230
500 510 520 530 540 550
pF1KB4 FQSIPRVFSKFPIKEARKPFNQNKNRYVDILPYDYNRVELSEINGDAGSNYINASYIDGF
:...: . . : : :..:::::.:::::..::.:. ..: :.:::::.:.:.
NP_543 FNALPACPIQATCEAASKEENKEKNRYVNILPYDHSRVHLTPVEGVPDSDYINASFINGY
240 250 260 270 280 290
560 570 580 590 600 610
pF1KB4 KEPRKYIAAQGPRDETVDDFWRMIWEQKATVIVMVTRCEEGNRNKCAEYWPSMEEGTRAF
.: :.::::::..:::.:::::::::....::::: .: .. :::.::: ..: ..
NP_543 QEKNKFIAAQGPKEETVNDFWRMIWEQNTATIVMVTNLKERKECKCAQYWP--DQGCWTY
300 310 320 330 340 350
620 630 640 650 660
pF1KB4 GDVVVKINQHKRCPDYIIQKL------NIVNKKEKATGREVTHIQFTSWPDHGVPEDPHL
:.. :.... :: ..:. ...:.: . : .:...:::::: ::: :
NP_543 GNIRVSVEDVTVLVDYTVRKFCIQQVGDMTNRKPQ---RLITQFHFTSWPDFGVPFTPIG
360 370 380 390 400 410
670 680 690 700 710 720
pF1KB4 LLKLRRRVNAFSNFFSGPIVVHCSAGVGRTGTYIGIDAMLEGLEAENKVDVYGYVVKLRR
.::. ..:.: . ..: ::::::::::::::.. :::::. ...: ::::::.: ..:
NP_543 MLKFLKKVKACNPQYAGAIVVHCSAGVGRTGTFVVIDAMLDMMHTERKVDVYGFVSRIRA
420 430 440 450 460 470
730 740 750 760 770 780
pF1KB4 QRCLMVQVEAQYILIHQALVEYNQFGETEVNLSELHPYLHNMKKRDPPSEPSPLEAEFQR
::: :::.. ::..:.:::.:. .:.::.... :. .:... .. : . . :: ::..
NP_543 QRCQMVQTDMQYVFIYQALLEHYLYGDTELEVTSLETHLQKIYNKIPGTSNNGLEEEFKK
480 490 500 510 520 530
790 800 810 820 830 840
pF1KB4 LPSYRSWRTQ-HIGNQEENKSKNRNSNVIPYDYNRVPLKHELEMSKESEHDSDESSDDDS
: : . . . :: : .::: ..:::..::: . :..:...:
NP_543 LTSIKIQNDKMRTGNLPANMKKNRVLQIIPYEFNRVIIP-----VKRGEENTD-------
540 550 560 570
850 860 870 880 890 900
pF1KB4 DSEEPSKYINASFIMSYWKPEVMIAAQGPLKETIGDFWQMIFQRKVKVIVMLTELKHGDQ
:.::::: .: . . .::.:::: .:: :::.::.. : :::::::.. :
NP_543 -------YVNASFIDGYRQKDSYIASQGPLLHTIEDFWRMIWEWKSCSIVMLTELEERGQ
580 590 600 610 620 630
910 920 930 940 950 960
pF1KB4 EICAQYW-GEGKQTYGDIEVDLKDTDKSSTYTLRVFELRHSKRKDSRTVYQYQYTNWSVE
: ::::: ..: .:::: :.:: .. .::.: . . ..... :: . :... .:
NP_543 EKCAQYWPSDGLVSYGDITVELKKEEECESYTVRDLLVTNTRENKSRQIRQFHFHGWPEV
640 650 660 670 680 690
970 980 990 1000 1010 1020
pF1KB4 QLPAEPKELISMIQVVKQKLPQKNSSEGNKHHKSTPLLIHCRDGSQQTGIFCALLNLLES
.:.. : .::.: .: ::.......: :. .:: :. .:: :::: ..::
NP_543 GIPSDGKGMISIIAAV-----QKQQQQSGNH----PITVHCSAGAGRTGTFCALSTVLER
700 710 720 730 740
1030 1040 1050 1060 1070 1080
pF1KB4 AETEEVVDIFQVVKALRKARPGMVSTFEQYQFLYDVIASTYPAQNGQVKKNNHQEDKIEF
...: ..:.::.::.:: :: ::.:.:::.: : :.
NP_543 VKAEGILDVFQTVKSLRLQRPHMVQTLEQYEFCYKVVQEYIDAFSDYANFK
750 760 770 780 790
1090 1100 1110 1120 1130 1140
pF1KB4 DNEVDKVKQDANCVNPLGAPEKLPEAKEQAEGSEPTSGTEGPEHSVNGPASPALNQGS
>>NP_543030 (OMIM: 176884) receptor-type tyrosine-protei (793 aa)
initn: 1453 init1: 490 opt: 1069 Z-score: 1035.3 bits: 202.9 E(85289): 6.3e-51
Smith-Waterman score: 1607; 39.9% identity (69.6% similar) in 667 aa overlap (418-1064:147-779)
390 400 410 420 430 440
pF1KB4 DYTFKAYFHNGDYPGEPFILHHSTSYNSKALIAFLAFLIIVTSIALLVVL-YKIYD----
..:. ..:.:: : .: .: .: :
NP_543 RTEPWEGNSSTAATTPETFPPSDETPIIAVMVALSSLLVIVFIIIVLYMLRFKKYKQAGS
120 130 140 150 160 170
450 460 470 480 490
pF1KB4 ------LHKKRSCNLDEQQ-ELVERDDEKQLMNVEPIHADILLETYKRKIADEGRLFLAE
: . :. ... :. :. :. . . :. .: : : .:..::...:: :
NP_543 HSNSFRLSNGRTEDVEPQSVPLLARSPSTN-RKYPPLPVDKLEEEINRRMADDNKLFREE
180 190 200 210 220 230
500 510 520 530 540 550
pF1KB4 FQSIPRVFSKFPIKEARKPFNQNKNRYVDILPYDYNRVELSEINGDAGSNYINASYIDGF
:...: . . : : :..:::::.:::::..::.:. ..: :.:::::.:.:.
NP_543 FNALPACPIQATCEAASKEENKEKNRYVNILPYDHSRVHLTPVEGVPDSDYINASFINGY
240 250 260 270 280 290
560 570 580 590 600 610
pF1KB4 KEPRKYIAAQGPRDETVDDFWRMIWEQKATVIVMVTRCEEGNRNKCAEYWPSMEEGTRAF
.: :.::::::..:::.:::::::::....::::: .: .. :::.::: ..: ..
NP_543 QEKNKFIAAQGPKEETVNDFWRMIWEQNTATIVMVTNLKERKECKCAQYWP--DQGCWTY
300 310 320 330 340 350
620 630 640 650 660
pF1KB4 GDVVVKINQHKRCPDYIIQKL------NIVNKKEKATGREVTHIQFTSWPDHGVPEDPHL
:.. :.... :: ..:. ...:.: . : .:...:::::: ::: :
NP_543 GNIRVSVEDVTVLVDYTVRKFCIQQVGDMTNRKPQ---RLITQFHFTSWPDFGVPFTPIG
360 370 380 390 400 410
670 680 690 700 710 720
pF1KB4 LLKLRRRVNAFSNFFSGPIVVHCSAGVGRTGTYIGIDAMLEGLEAENKVDVYGYVVKLRR
.::. ..:.: . ..: ::::::::::::::.. :::::. ...: ::::::.: ..:
NP_543 MLKFLKKVKACNPQYAGAIVVHCSAGVGRTGTFVVIDAMLDMMHTERKVDVYGFVSRIRA
420 430 440 450 460 470
730 740 750 760 770 780
pF1KB4 QRCLMVQVEAQYILIHQALVEYNQFGETEVNLSELHPYLHNMKKRDPPSEPSPLEAEFQR
::: :::.. ::..:.:::.:. .:.::.... :. .:... .. : . . :: ::..
NP_543 QRCQMVQTDMQYVFIYQALLEHYLYGDTELEVTSLETHLQKIYNKIPGTSNNGLEEEFKK
480 490 500 510 520 530
790 800 810 820 830 840
pF1KB4 LPSYRSWRTQ-HIGNQEENKSKNRNSNVIPYDYNRVPLKHELEMSKESEHDSDESSDDDS
: : . . . :: : .::: ..:::..::: . :..:...:
NP_543 LTSIKIQNDKMRTGNLPANMKKNRVLQIIPYEFNRVIIP-----VKRGEENTD-------
540 550 560 570
850 860 870 880 890 900
pF1KB4 DSEEPSKYINASFIMSYWKPEVMIAAQGPLKETIGDFWQMIFQRKVKVIVMLTELKHGDQ
:.::::: .: . . .::.:::: .:: :::.::.. : :::::::.. :
NP_543 -------YVNASFIDGYRQKDSYIASQGPLLHTIEDFWRMIWEWKSCSIVMLTELEERGQ
580 590 600 610 620 630
910 920 930 940 950 960
pF1KB4 EICAQYW-GEGKQTYGDIEVDLKDTDKSSTYTLRVFELRHSKRKDSRTVYQYQYTNWSVE
: ::::: ..: .:::: :.:: .. .::.: . . ..... :: . :... .:
NP_543 EKCAQYWPSDGLVSYGDITVELKKEEECESYTVRDLLVTNTRENKSRQIRQFHFHGWPEV
640 650 660 670 680 690
970 980 990 1000 1010 1020
pF1KB4 QLPAEPKELISMIQVVKQKLPQKNSSEGNKHHKSTPLLIHCRDGSQQTGIFCALLNLLES
.:.. : .::.: .: ::.......: :. .:: :. .:: :::: ..::
NP_543 GIPSDGKGMISIIAAV-----QKQQQQSGNH----PITVHCSAGAGRTGTFCALSTVLER
700 710 720 730 740
1030 1040 1050 1060 1070 1080
pF1KB4 AETEEVVDIFQVVKALRKARPGMVSTFEQYQFLYDVIASTYPAQNGQVKKNNHQEDKIEF
...: ..:.::.::.:: :: ::.:.:::.: : :.
NP_543 VKAEGILDVFQTVKSLRLQRPHMVQTLEQYEFCYKVVQEYIDAFSDYANFK
750 760 770 780 790
1090 1100 1110 1120 1130 1140
pF1KB4 DNEVDKVKQDANCVNPLGAPEKLPEAKEQAEGSEPTSGTEGPEHSVNGPASPALNQGS
>>NP_002827 (OMIM: 176884) receptor-type tyrosine-protei (802 aa)
initn: 1453 init1: 490 opt: 1069 Z-score: 1035.2 bits: 202.9 E(85289): 6.3e-51
Smith-Waterman score: 1607; 39.9% identity (69.6% similar) in 667 aa overlap (418-1064:156-788)
390 400 410 420 430 440
pF1KB4 DYTFKAYFHNGDYPGEPFILHHSTSYNSKALIAFLAFLIIVTSIALLVVL-YKIYD----
..:. ..:.:: : .: .: .: :
NP_002 STAATTPETFPPSGNSDSKDRRDETPIIAVMVALSSLLVIVFIIIVLYMLRFKKYKQAGS
130 140 150 160 170 180
450 460 470 480 490
pF1KB4 ------LHKKRSCNLDEQQ-ELVERDDEKQLMNVEPIHADILLETYKRKIADEGRLFLAE
: . :. ... :. :. :. . . :. .: : : .:..::...:: :
NP_002 HSNSFRLSNGRTEDVEPQSVPLLARSPSTN-RKYPPLPVDKLEEEINRRMADDNKLFREE
190 200 210 220 230 240
500 510 520 530 540 550
pF1KB4 FQSIPRVFSKFPIKEARKPFNQNKNRYVDILPYDYNRVELSEINGDAGSNYINASYIDGF
:...: . . : : :..:::::.:::::..::.:. ..: :.:::::.:.:.
NP_002 FNALPACPIQATCEAASKEENKEKNRYVNILPYDHSRVHLTPVEGVPDSDYINASFINGY
250 260 270 280 290 300
560 570 580 590 600 610
pF1KB4 KEPRKYIAAQGPRDETVDDFWRMIWEQKATVIVMVTRCEEGNRNKCAEYWPSMEEGTRAF
.: :.::::::..:::.:::::::::....::::: .: .. :::.::: ..: ..
NP_002 QEKNKFIAAQGPKEETVNDFWRMIWEQNTATIVMVTNLKERKECKCAQYWP--DQGCWTY
310 320 330 340 350 360
620 630 640 650 660
pF1KB4 GDVVVKINQHKRCPDYIIQKL------NIVNKKEKATGREVTHIQFTSWPDHGVPEDPHL
:.. :.... :: ..:. ...:.: . : .:...:::::: ::: :
NP_002 GNIRVSVEDVTVLVDYTVRKFCIQQVGDMTNRKPQ---RLITQFHFTSWPDFGVPFTPIG
370 380 390 400 410
670 680 690 700 710 720
pF1KB4 LLKLRRRVNAFSNFFSGPIVVHCSAGVGRTGTYIGIDAMLEGLEAENKVDVYGYVVKLRR
.::. ..:.: . ..: ::::::::::::::.. :::::. ...: ::::::.: ..:
NP_002 MLKFLKKVKACNPQYAGAIVVHCSAGVGRTGTFVVIDAMLDMMHTERKVDVYGFVSRIRA
420 430 440 450 460 470
730 740 750 760 770 780
pF1KB4 QRCLMVQVEAQYILIHQALVEYNQFGETEVNLSELHPYLHNMKKRDPPSEPSPLEAEFQR
::: :::.. ::..:.:::.:. .:.::.... :. .:... .. : . . :: ::..
NP_002 QRCQMVQTDMQYVFIYQALLEHYLYGDTELEVTSLETHLQKIYNKIPGTSNNGLEEEFKK
480 490 500 510 520 530
790 800 810 820 830 840
pF1KB4 LPSYRSWRTQ-HIGNQEENKSKNRNSNVIPYDYNRVPLKHELEMSKESEHDSDESSDDDS
: : . . . :: : .::: ..:::..::: . :..:...:
NP_002 LTSIKIQNDKMRTGNLPANMKKNRVLQIIPYEFNRVIIP-----VKRGEENTD-------
540 550 560 570 580
850 860 870 880 890 900
pF1KB4 DSEEPSKYINASFIMSYWKPEVMIAAQGPLKETIGDFWQMIFQRKVKVIVMLTELKHGDQ
:.::::: .: . . .::.:::: .:: :::.::.. : :::::::.. :
NP_002 -------YVNASFIDGYRQKDSYIASQGPLLHTIEDFWRMIWEWKSCSIVMLTELEERGQ
590 600 610 620 630 640
910 920 930 940 950 960
pF1KB4 EICAQYW-GEGKQTYGDIEVDLKDTDKSSTYTLRVFELRHSKRKDSRTVYQYQYTNWSVE
: ::::: ..: .:::: :.:: .. .::.: . . ..... :: . :... .:
NP_002 EKCAQYWPSDGLVSYGDITVELKKEEECESYTVRDLLVTNTRENKSRQIRQFHFHGWPEV
650 660 670 680 690 700
970 980 990 1000 1010 1020
pF1KB4 QLPAEPKELISMIQVVKQKLPQKNSSEGNKHHKSTPLLIHCRDGSQQTGIFCALLNLLES
.:.. : .::.: .: ::.......: :. .:: :. .:: :::: ..::
NP_002 GIPSDGKGMISIIAAV-----QKQQQQSGNH----PITVHCSAGAGRTGTFCALSTVLER
710 720 730 740 750
1030 1040 1050 1060 1070 1080
pF1KB4 AETEEVVDIFQVVKALRKARPGMVSTFEQYQFLYDVIASTYPAQNGQVKKNNHQEDKIEF
...: ..:.::.::.:: :: ::.:.:::.: : :.
NP_002 VKAEGILDVFQTVKSLRLQRPHMVQTLEQYEFCYKVVQEYIDAFSDYANFK
760 770 780 790 800
1090 1100 1110 1120 1130 1140
pF1KB4 DNEVDKVKQDANCVNPLGAPEKLPEAKEQAEGSEPTSGTEGPEHSVNGPASPALNQGS
>>XP_011538298 (OMIM: 600926) PREDICTED: receptor-type t (678 aa)
initn: 1280 init1: 850 opt: 996 Z-score: 965.8 bits: 189.9 E(85289): 4.7e-47
Smith-Waterman score: 1339; 37.1% identity (65.3% similar) in 668 aa overlap (415-1064:64-664)
390 400 410 420 430 440
pF1KB4 YSTDYTFKAYFHNGDYPGEPFILHHSTSYNSKALIAFLAFLIIVTSIALLVVLYKIYDLH
:. :.:.: . ... ..::.. : .. ..
XP_011 LPLARALRGNETTADSNETTTTSGPPDPGASQPLLAWLLLPLLLLLLVLLLAAY-FFRFR
40 50 60 70 80 90
450 460 470 480
pF1KB4 KKRSCNLDEQQE-----LVERDDEKQLMNVE----------PIHADILLETYKRKIADEG
:.:. .. ... ..:.......: . :: .. : : . . ::.
XP_011 KQRKAVVSTSDKKMPNGILEEQEQQRVMLLSRSPSGPKKYFPIPVEHLEEEIRIRSADDC
100 110 120 130 140 150
490 500 510 520 530 540
pF1KB4 RLFLAEFQSIPRVFSKFPIKEARKPFNQNKNRYVDILPYDYNRVELSEINGDAGSNYINA
. : ::.:.: . .. : : :..:::: .::: :..:: ::...: :.::::
XP_011 KQFREEFNSLPSGHIQGTFELANKEENREKNRYPNILPNDHSRVILSQLDGIPCSDYINA
160 170 180 190 200 210
550 560 570 580 590 600
pF1KB4 SYIDGFKEPRKYIAAQGPRDETVDDFWRMIWEQKATVIVMVTRCEEGNRNKCAEYWPSME
:::::.:: :.::::::..:::.:::::.::::...:::.: .: ...:: .::: .
XP_011 SYIDGYKEKNKFIAAQGPKQETVNDFWRMVWEQKSATIVMLTNLKERKEEKCHQYWP--D
220 230 240 250 260 270
610 620 630 640 650 660
pF1KB4 EGTRAFGDVVVKINQHKRCPDYIIQKLNIVNKKEKA--TGREVTHIQFTSWPDHGVPEDP
.: ..:.. : ... :: :.:. : . . . : :....:::::: ::: :
XP_011 QGCWTYGNIRVCVEDCVVLVDYTIRKFCIQPQLPDGCKAPRLVSQLHFTSWPDFGVPFTP
280 290 300 310 320 330
670 680 690 700 710 720
pF1KB4 HLLLKLRRRVNAFSNFFSGPIVVHCSAGVGRTGTYIGIDAMLEGLEAENKVDVYGYVVKL
.::. ..:.... .::::::::::::::::.: ::::. ..::.::::. .: ..
XP_011 IGMLKFLKKVKTLNPVHAGPIVVHCSAGVGRTGTFIVIDAMMAMMHAEQKVDVFEFVSRI
340 350 360 370 380 390
730 740 750 760 770 780
pF1KB4 RRQRCLMVQVEAQYILIHQALVEYNQFGETEVNLSELHPYLHNMKKRDPPSEPSPLEAEF
: :: :::.. :: .:.:::.:: .:.::...: :. .:..:. . :: ::
XP_011 RNQRPQMVQTDMQYTFIYQALLEYYLYGDTELDVSSLEKHLQTMHGTTTHFDKIGLEEEF
400 410 420 430 440 450
790 800 810 820 830 840
pF1KB4 QRLPSYRSWR-TQHIGNQEENKSKNRNSNVIPYDYNRVPLKHELEMSKESEHDSDESSDD
..: . : . ... :: : .: : ..::::.::: :. :.. .:.
XP_011 RKLTNVRIMKENMRTGNLPANMKKARVIQIIPYDFNRVILS----MKRGQEY--------
460 470 480 490
850 860 870 880 890 900
pF1KB4 DSDSEEPSKYINASFIMSYWKPEVMIAAQGPLKETIGDFWQMIFQRKVKVIVMLTELKHG
. ::::::: .: . . .::.:::: .:. :::.::.. : ..::::::...
XP_011 -------TDYINASFIDGYRQKDYFIATQGPLAHTVEDFWRMIWEWKSHTIVMLTEVQER
500 510 520 530 540 550
910 920 930 940 950 960
pF1KB4 DQEICAQYWGEGKQTYGDIEVDLKDTDKSSTYTLRVFELRHSKRKDSRTVYQYQYTNWSV
.: ...: ... :.: :... .:
XP_011 EQP-------QARQ-----------------------------EEQVRVVRQFHFHGWPE
560 570
970 980 990 1000 1010 1020
pF1KB4 EQLPAEPKELISMIQVVKQKLPQKNSSEGNKHHKSTPLLIHCRDGSQQTGIFCALLNLLE
.::: : .:..: .: :: :.. ::. :. .:: :. .:: : :: :.::
XP_011 IGIPAEGKGMIDLIAAV-QKQQQQT---GNH-----PITVHCSAGAGRTGTFIALSNILE
580 590 600 610 620
1030 1040 1050 1060 1070 1080
pF1KB4 SAETEEVVDIFQVVKALRKARPGMVSTFEQYQFLYDVIASTYPAQNGQVKKNNHQEDKIE
...: ..:.::.::.:: :: ::.:.:::.: : :.
XP_011 RVKAEGLLDVFQAVKSLRLQRPHMVQTLEQYEFCYKVVQDFIDIFSDYANFK
630 640 650 660 670
1090 1100 1110 1120 1130 1140
pF1KB4 FDNEVDKVKQDANCVNPLGAPEKLPEAKEQAEGSEPTSGTEGPEHSVNGPASPALNQGS
>>XP_011538296 (OMIM: 600926) PREDICTED: receptor-type t (719 aa)
initn: 1304 init1: 461 opt: 993 Z-score: 962.5 bits: 189.3 E(85289): 7.1e-47
Smith-Waterman score: 1486; 39.0% identity (68.1% similar) in 674 aa overlap (415-1064:64-705)
390 400 410 420 430 440
pF1KB4 YSTDYTFKAYFHNGDYPGEPFILHHSTSYNSKALIAFLAFLIIVTSIALLVVLYKIYDLH
:. :.:.: . ... ..::.. : .. ..
XP_011 LPLARALRGNETTADSNETTTTSGPPDPGASQPLLAWLLLPLLLLLLVLLLAAY-FFRFR
40 50 60 70 80 90
450 460 470 480
pF1KB4 KKRSCNLDEQQE-----LVERDDEKQLMNVE----------PIHADILLETYKRKIADEG
:.:. .. ... ..:.......: . :: .. : : . . ::.
XP_011 KQRKAVVSTSDKKMPNGILEEQEQQRVMLLSRSPSGPKKYFPIPVEHLEEEIRIRSADDC
100 110 120 130 140 150
490 500 510 520 530 540
pF1KB4 RLFLAEFQSIPRVFSKFPIKEARKPFNQNKNRYVDILPYDYNRVELSEINGDAGSNYINA
. : ::.:.: . .. : : :..:::: .::: :..:: ::...: :.::::
XP_011 KQFREEFNSLPSGHIQGTFELANKEENREKNRYPNILPNDHSRVILSQLDGIPCSDYINA
160 170 180 190 200 210
550 560 570 580 590 600
pF1KB4 SYIDGFKEPRKYIAAQGPRDETVDDFWRMIWEQKATVIVMVTRCEEGNRNKCAEYWPSME
:::::.:: :.::::::..:::.:::::.::::...:::.: .: ...:: .::: .
XP_011 SYIDGYKEKNKFIAAQGPKQETVNDFWRMVWEQKSATIVMLTNLKERKEEKCHQYWP--D
220 230 240 250 260 270
610 620 630 640 650 660
pF1KB4 EGTRAFGDVVVKINQHKRCPDYIIQKLNIVNKKE--KATGREVTHIQFTSWPDHGVPEDP
.: ..:.. : ... :: :.:. : . :: : :....:::::: ::: :
XP_011 QGCWTYGNIRVCVEDCVVLVDYTIRKFCIQPLPDGCKAP-RLVSQLHFTSWPDFGVPFTP
280 290 300 310 320
670 680 690 700 710 720
pF1KB4 HLLLKLRRRVNAFSNFFSGPIVVHCSAGVGRTGTYIGIDAMLEGLEAENKVDVYGYVVKL
.::. ..:.... .::::::::::::::::.: ::::. ..::.::::. .: ..
XP_011 IGMLKFLKKVKTLNPVHAGPIVVHCSAGVGRTGTFIVIDAMMAMMHAEQKVDVFEFVSRI
330 340 350 360 370 380
730 740 750 760 770 780
pF1KB4 RRQRCLMVQVEAQYILIHQALVEYNQFGETEVNLSELHPYLHNMKKRDPPSEPSPLEAEF
: :: :::.. :: .:.:::.:: .:.::...: :. .:..:. . :: ::
XP_011 RNQRPQMVQTDMQYTFIYQALLEYYLYGDTELDVSSLEKHLQTMHGTTTHFDKIGLEEEF
390 400 410 420 430 440
790 800 810 820 830 840
pF1KB4 QRLPSYRSWR-TQHIGNQEENKSKNRNSNVIPYDYNRVPLKHELEMSKESEHDSDESSDD
..: . : . ... :: : .: : ..::::.::: :. :.. .:.
XP_011 RKLTNVRIMKENMRTGNLPANMKKARVIQIIPYDFNRVILS----MKRGQEY--------
450 460 470 480 490
850 860 870 880 890 900
pF1KB4 DSDSEEPSKYINASFIMSYWKPEVMIAAQGPLKETIGDFWQMIFQRKVKVIVMLTELKHG
. ::::::: .: . . .::.:::: .:. :::.::.. : ..::::::...
XP_011 -------TDYINASFIDGYRQKDYFIATQGPLAHTVEDFWRMIWEWKSHTIVMLTEVQER
500 510 520 530 540 550
910 920 930 940 950 960
pF1KB4 DQEICAQYWG-EGKQTYGDIEVDLKDTDKSSTYTLRVFELRHSK---RKDS--RTVYQYQ
.:. : ::: ::. :.:.: ...:. : . ..: : . .. :.. :.: :..
XP_011 EQDKCYQYWPTEGSVTHGEITIEIKNDTLSEAISIRDFLVTLNQPQARQEEQVRVVRQFH
560 570 580 590 600 610
970 980 990 1000 1010 1020
pF1KB4 YTNWSVEQLPAEPKELISMIQVVKQKLPQKNSSEGNKHHKSTPLLIHCRDGSQQTGIFCA
. .: .::: : .:..: .: :: :.. ::. :. .:: :. .:: : :
XP_011 FHGWPEIGIPAEGKGMIDLIAAV-QKQQQQT---GNH-----PITVHCSAGAGRTGTFIA
620 630 640 650 660
1030 1040 1050 1060 1070 1080
pF1KB4 LLNLLESAETEEVVDIFQVVKALRKARPGMVSTFEQYQFLYDVIASTYPAQNGQVKKNNH
: :.:: ...: ..:.::.::.:: :: ::.:.:::.: : :.
XP_011 LSNILERVKAEGLLDVFQAVKSLRLQRPHMVQTLEQYEFCYKVVQDFIDIFSDYANFK
670 680 690 700 710
1090 1100 1110 1120 1130 1140
pF1KB4 QEDKIEFDNEVDKVKQDANCVNPLGAPEKLPEAKEQAEGSEPTSGTEGPEHSVNGPASPA
1145 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sat Nov 5 07:13:29 2016 done: Sat Nov 5 07:13:31 2016
Total Scan time: 10.800 Total Display time: 0.470
Function used was FASTA [36.3.4 Apr, 2011]