Result of FASTA (omim) for
pFN21AB3919
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB3919, 579 aa
1>>>pF1KB3919 579 - 579 aa - 579 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 7.0092+/-0.000349; mu= 14.2328+/- 0.022
mean_var=160.6443+/-34.740, 0's: 0 Z-trim(118.8): 95 B-trim: 1497 in 1/56
Lambda= 0.101191
statistics sampled from 32094 (32198) to 32094 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.693), E-opt: 0.2 (0.378), width: 16
Scan time: 10.860
The best scores are: opt bits E(85289)
NP_006538 (OMIM: 608259) insulin-like growth facto ( 579) 3772 562.7 1.2e-159
XP_011513391 (OMIM: 608259) PREDICTED: insulin-lik ( 584) 3752 559.8 9.1e-159
XP_011513394 (OMIM: 608259) PREDICTED: insulin-lik ( 486) 3131 469.0 1.6e-131
XP_011513395 (OMIM: 608259) PREDICTED: insulin-lik ( 486) 3131 469.0 1.6e-131
XP_011513392 (OMIM: 608259) PREDICTED: insulin-lik ( 471) 2893 434.3 4.4e-121
XP_011522503 (OMIM: 608288) PREDICTED: insulin-lik ( 576) 2817 423.3 1.1e-117
NP_006537 (OMIM: 608288) insulin-like growth facto ( 577) 2815 423.0 1.4e-117
XP_016879511 (OMIM: 608288) PREDICTED: insulin-lik ( 575) 2789 419.2 1.9e-116
XP_011513393 (OMIM: 608259) PREDICTED: insulin-lik ( 422) 2744 412.5 1.4e-114
XP_006715702 (OMIM: 608259) PREDICTED: insulin-lik ( 422) 2744 412.5 1.4e-114
XP_005257012 (OMIM: 608288) PREDICTED: insulin-lik ( 565) 2429 366.6 1.2e-100
NP_006539 (OMIM: 125853,608289) insulin-like growt ( 599) 1676 256.7 1.6e-67
XP_016861051 (OMIM: 125853,608289) PREDICTED: insu ( 473) 1654 253.4 1.2e-66
XP_016861050 (OMIM: 125853,608289) PREDICTED: insu ( 492) 1654 253.4 1.3e-66
XP_016861048 (OMIM: 125853,608289) PREDICTED: insu ( 561) 1654 253.5 1.4e-66
NP_001278798 (OMIM: 125853,608289) insulin-like gr ( 605) 1654 253.5 1.5e-66
NP_001007226 (OMIM: 125853,608289) insulin-like gr ( 556) 1573 241.6 5e-63
XP_016861052 (OMIM: 125853,608289) PREDICTED: insu ( 375) 1552 238.4 3.2e-62
XP_016861053 (OMIM: 125853,608289) PREDICTED: insu ( 375) 1552 238.4 3.2e-62
XP_016861047 (OMIM: 125853,608289) PREDICTED: insu ( 562) 1551 238.4 4.7e-62
NP_001153895 (OMIM: 608288) insulin-like growth fa ( 438) 1529 235.1 3.6e-61
XP_016861046 (OMIM: 125853,608289) PREDICTED: insu ( 596) 1381 213.6 1.4e-54
XP_016861049 (OMIM: 125853,608289) PREDICTED: insu ( 537) 1366 211.4 6.1e-54
NP_001278802 (OMIM: 125853,608289) insulin-like gr ( 536) 1351 209.2 2.8e-53
NP_001278801 (OMIM: 125853,608289) insulin-like gr ( 542) 1329 206.0 2.6e-52
NP_001278803 (OMIM: 125853,608289) insulin-like gr ( 493) 1248 194.1 8.9e-49
NP_001278804 (OMIM: 125853,608289) insulin-like gr ( 463) 1069 168.0 6.2e-41
XP_006713540 (OMIM: 125853,608289) PREDICTED: insu ( 343) 885 141.0 6.1e-33
XP_006713541 (OMIM: 125853,608289) PREDICTED: insu ( 300) 871 138.9 2.3e-32
XP_016876831 (OMIM: 602157) PREDICTED: RNA-binding ( 470) 253 48.9 4.6e-05
NP_002506 (OMIM: 602157) RNA-binding protein Nova- ( 507) 244 47.6 0.00012
NP_001290362 (OMIM: 603444) far upstream element-b ( 665) 237 46.7 0.00029
XP_016858229 (OMIM: 603444) PREDICTED: far upstrea ( 675) 237 46.7 0.0003
XP_016858228 (OMIM: 603444) PREDICTED: far upstrea ( 688) 237 46.7 0.0003
XP_011540693 (OMIM: 603444) PREDICTED: far upstrea ( 688) 237 46.7 0.0003
NP_003893 (OMIM: 603444) far upstream element-bind ( 644) 236 46.5 0.00032
XP_016858231 (OMIM: 603444) PREDICTED: far upstrea ( 664) 236 46.5 0.00033
XP_011540695 (OMIM: 603444) PREDICTED: far upstrea ( 667) 236 46.5 0.00033
XP_011540694 (OMIM: 603444) PREDICTED: far upstrea ( 687) 236 46.5 0.00033
XP_016858233 (OMIM: 603444) PREDICTED: far upstrea ( 643) 235 46.4 0.00035
XP_016858232 (OMIM: 603444) PREDICTED: far upstrea ( 653) 235 46.4 0.00036
XP_016858230 (OMIM: 603444) PREDICTED: far upstrea ( 666) 235 46.4 0.00036
XP_011517475 (OMIM: 603536) PREDICTED: far upstrea ( 499) 219 43.9 0.0015
XP_011517474 (OMIM: 603536) PREDICTED: far upstrea ( 514) 219 43.9 0.0015
XP_005272289 (OMIM: 603536) PREDICTED: far upstrea ( 548) 219 44.0 0.0016
XP_016882898 (OMIM: 603445) PREDICTED: far upstrea ( 642) 220 44.2 0.0016
NP_003925 (OMIM: 603536) far upstream element-bind ( 572) 219 44.0 0.0016
XP_016882897 (OMIM: 603445) PREDICTED: far upstrea ( 678) 220 44.2 0.0017
XP_011526697 (OMIM: 603445) PREDICTED: far upstrea ( 703) 220 44.2 0.0017
NP_003676 (OMIM: 603445) far upstream element-bind ( 711) 220 44.2 0.0017
>>NP_006538 (OMIM: 608259) insulin-like growth factor 2 (579 aa)
initn: 3772 init1: 3772 opt: 3772 Z-score: 2987.2 bits: 562.7 E(85289): 1.2e-159
Smith-Waterman score: 3772; 100.0% identity (100.0% similar) in 579 aa overlap (1-579:1-579)
10 20 30 40 50 60
pF1KB3 MNKLYIGNLSENAAPSDLESIFKDAKIPVSGPFLVKTGYAFVDCPDESWALKAIEALSGK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 MNKLYIGNLSENAAPSDLESIFKDAKIPVSGPFLVKTGYAFVDCPDESWALKAIEALSGK
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB3 IELHGKPIEVEHSVPKRQRIRKLQIRNIPPHLQWEVLDSLLVQYGVVESCEQVNTDSETA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 IELHGKPIEVEHSVPKRQRIRKLQIRNIPPHLQWEVLDSLLVQYGVVESCEQVNTDSETA
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB3 VVNVTYSSKDQARQALDKLNGFQLENFTLKVAYIPDEMAAQQNPLQQPRGRRGLGQRGSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 VVNVTYSSKDQARQALDKLNGFQLENFTLKVAYIPDEMAAQQNPLQQPRGRRGLGQRGSS
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB3 RQGSPGSVSKQKPCDLPLRLLVPTQFVGAIIGKEGATIRNITKQTQSKIDVHRKENAGAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 RQGSPGSVSKQKPCDLPLRLLVPTQFVGAIIGKEGATIRNITKQTQSKIDVHRKENAGAA
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB3 EKSITILSTPEGTSAACKSILEIMHKEAQDIKFTEEIPLKILAHNNFVGRLIGKEGRNLK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 EKSITILSTPEGTSAACKSILEIMHKEAQDIKFTEEIPLKILAHNNFVGRLIGKEGRNLK
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB3 KIEQDTDTKITISPLQELTLYNPERTITVKGNVETCAKAEEEIMKKIRESYENDIASMNL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 KIEQDTDTKITISPLQELTLYNPERTITVKGNVETCAKAEEEIMKKIRESYENDIASMNL
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB3 QAHLIPGLNLNALGLFPPTSGMPPPTSGPPSAMTPPYPQFEQSETETVHLFIPALSVGAI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 QAHLIPGLNLNALGLFPPTSGMPPPTSGPPSAMTPPYPQFEQSETETVHLFIPALSVGAI
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB3 IGKQGQHIKQLSRFAGASIKIAPAEAPDAKVRMVIITGPPEAQFKAQGRIYGKIKEENFV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 IGKQGQHIKQLSRFAGASIKIAPAEAPDAKVRMVIITGPPEAQFKAQGRIYGKIKEENFV
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB3 SPKEEVKLEAHIRVPSFAAGRVIGKGGKTVNELQNLSSAEVVVPRDQTPDENDQVVVKIT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 SPKEEVKLEAHIRVPSFAAGRVIGKGGKTVNELQNLSSAEVVVPRDQTPDENDQVVVKIT
490 500 510 520 530 540
550 560 570
pF1KB3 GHFYACQVAQRKIQEILTQVKQHQQQKALQSGPPQSRRK
:::::::::::::::::::::::::::::::::::::::
NP_006 GHFYACQVAQRKIQEILTQVKQHQQQKALQSGPPQSRRK
550 560 570
>>XP_011513391 (OMIM: 608259) PREDICTED: insulin-like gr (584 aa)
initn: 3131 init1: 3131 opt: 3752 Z-score: 2971.4 bits: 559.8 E(85289): 9.1e-159
Smith-Waterman score: 3752; 99.1% identity (99.1% similar) in 584 aa overlap (1-579:1-584)
10 20 30 40 50 60
pF1KB3 MNKLYIGNLSENAAPSDLESIFKDAKIPVSGPFLVKTGYAFVDCPDESWALKAIEALSGK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MNKLYIGNLSENAAPSDLESIFKDAKIPVSGPFLVKTGYAFVDCPDESWALKAIEALSGK
10 20 30 40 50 60
70 80 90 100 110
pF1KB3 IELHGKPIEVEHSVPKRQRIRKLQIRNIPPHLQWE-----VLDSLLVQYGVVESCEQVNT
::::::::::::::::::::::::::::::::::: ::::::::::::::::::::
XP_011 IELHGKPIEVEHSVPKRQRIRKLQIRNIPPHLQWESPKMTVLDSLLVQYGVVESCEQVNT
70 80 90 100 110 120
120 130 140 150 160 170
pF1KB3 DSETAVVNVTYSSKDQARQALDKLNGFQLENFTLKVAYIPDEMAAQQNPLQQPRGRRGLG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DSETAVVNVTYSSKDQARQALDKLNGFQLENFTLKVAYIPDEMAAQQNPLQQPRGRRGLG
130 140 150 160 170 180
180 190 200 210 220 230
pF1KB3 QRGSSRQGSPGSVSKQKPCDLPLRLLVPTQFVGAIIGKEGATIRNITKQTQSKIDVHRKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QRGSSRQGSPGSVSKQKPCDLPLRLLVPTQFVGAIIGKEGATIRNITKQTQSKIDVHRKE
190 200 210 220 230 240
240 250 260 270 280 290
pF1KB3 NAGAAEKSITILSTPEGTSAACKSILEIMHKEAQDIKFTEEIPLKILAHNNFVGRLIGKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NAGAAEKSITILSTPEGTSAACKSILEIMHKEAQDIKFTEEIPLKILAHNNFVGRLIGKE
250 260 270 280 290 300
300 310 320 330 340 350
pF1KB3 GRNLKKIEQDTDTKITISPLQELTLYNPERTITVKGNVETCAKAEEEIMKKIRESYENDI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GRNLKKIEQDTDTKITISPLQELTLYNPERTITVKGNVETCAKAEEEIMKKIRESYENDI
310 320 330 340 350 360
360 370 380 390 400 410
pF1KB3 ASMNLQAHLIPGLNLNALGLFPPTSGMPPPTSGPPSAMTPPYPQFEQSETETVHLFIPAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ASMNLQAHLIPGLNLNALGLFPPTSGMPPPTSGPPSAMTPPYPQFEQSETETVHLFIPAL
370 380 390 400 410 420
420 430 440 450 460 470
pF1KB3 SVGAIIGKQGQHIKQLSRFAGASIKIAPAEAPDAKVRMVIITGPPEAQFKAQGRIYGKIK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SVGAIIGKQGQHIKQLSRFAGASIKIAPAEAPDAKVRMVIITGPPEAQFKAQGRIYGKIK
430 440 450 460 470 480
480 490 500 510 520 530
pF1KB3 EENFVSPKEEVKLEAHIRVPSFAAGRVIGKGGKTVNELQNLSSAEVVVPRDQTPDENDQV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EENFVSPKEEVKLEAHIRVPSFAAGRVIGKGGKTVNELQNLSSAEVVVPRDQTPDENDQV
490 500 510 520 530 540
540 550 560 570
pF1KB3 VVKITGHFYACQVAQRKIQEILTQVKQHQQQKALQSGPPQSRRK
::::::::::::::::::::::::::::::::::::::::::::
XP_011 VVKITGHFYACQVAQRKIQEILTQVKQHQQQKALQSGPPQSRRK
550 560 570 580
>>XP_011513394 (OMIM: 608259) PREDICTED: insulin-like gr (486 aa)
initn: 3131 init1: 3131 opt: 3131 Z-score: 2482.5 bits: 469.0 E(85289): 1.6e-131
Smith-Waterman score: 3131; 100.0% identity (100.0% similar) in 484 aa overlap (96-579:3-486)
70 80 90 100 110 120
pF1KB3 KPIEVEHSVPKRQRIRKLQIRNIPPHLQWEVLDSLLVQYGVVESCEQVNTDSETAVVNVT
::::::::::::::::::::::::::::::
XP_011 MTVLDSLLVQYGVVESCEQVNTDSETAVVNVT
10 20 30
130 140 150 160 170 180
pF1KB3 YSSKDQARQALDKLNGFQLENFTLKVAYIPDEMAAQQNPLQQPRGRRGLGQRGSSRQGSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YSSKDQARQALDKLNGFQLENFTLKVAYIPDEMAAQQNPLQQPRGRRGLGQRGSSRQGSP
40 50 60 70 80 90
190 200 210 220 230 240
pF1KB3 GSVSKQKPCDLPLRLLVPTQFVGAIIGKEGATIRNITKQTQSKIDVHRKENAGAAEKSIT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GSVSKQKPCDLPLRLLVPTQFVGAIIGKEGATIRNITKQTQSKIDVHRKENAGAAEKSIT
100 110 120 130 140 150
250 260 270 280 290 300
pF1KB3 ILSTPEGTSAACKSILEIMHKEAQDIKFTEEIPLKILAHNNFVGRLIGKEGRNLKKIEQD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ILSTPEGTSAACKSILEIMHKEAQDIKFTEEIPLKILAHNNFVGRLIGKEGRNLKKIEQD
160 170 180 190 200 210
310 320 330 340 350 360
pF1KB3 TDTKITISPLQELTLYNPERTITVKGNVETCAKAEEEIMKKIRESYENDIASMNLQAHLI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TDTKITISPLQELTLYNPERTITVKGNVETCAKAEEEIMKKIRESYENDIASMNLQAHLI
220 230 240 250 260 270
370 380 390 400 410 420
pF1KB3 PGLNLNALGLFPPTSGMPPPTSGPPSAMTPPYPQFEQSETETVHLFIPALSVGAIIGKQG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PGLNLNALGLFPPTSGMPPPTSGPPSAMTPPYPQFEQSETETVHLFIPALSVGAIIGKQG
280 290 300 310 320 330
430 440 450 460 470 480
pF1KB3 QHIKQLSRFAGASIKIAPAEAPDAKVRMVIITGPPEAQFKAQGRIYGKIKEENFVSPKEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QHIKQLSRFAGASIKIAPAEAPDAKVRMVIITGPPEAQFKAQGRIYGKIKEENFVSPKEE
340 350 360 370 380 390
490 500 510 520 530 540
pF1KB3 VKLEAHIRVPSFAAGRVIGKGGKTVNELQNLSSAEVVVPRDQTPDENDQVVVKITGHFYA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VKLEAHIRVPSFAAGRVIGKGGKTVNELQNLSSAEVVVPRDQTPDENDQVVVKITGHFYA
400 410 420 430 440 450
550 560 570
pF1KB3 CQVAQRKIQEILTQVKQHQQQKALQSGPPQSRRK
::::::::::::::::::::::::::::::::::
XP_011 CQVAQRKIQEILTQVKQHQQQKALQSGPPQSRRK
460 470 480
>>XP_011513395 (OMIM: 608259) PREDICTED: insulin-like gr (486 aa)
initn: 3131 init1: 3131 opt: 3131 Z-score: 2482.5 bits: 469.0 E(85289): 1.6e-131
Smith-Waterman score: 3131; 100.0% identity (100.0% similar) in 484 aa overlap (96-579:3-486)
70 80 90 100 110 120
pF1KB3 KPIEVEHSVPKRQRIRKLQIRNIPPHLQWEVLDSLLVQYGVVESCEQVNTDSETAVVNVT
::::::::::::::::::::::::::::::
XP_011 MTVLDSLLVQYGVVESCEQVNTDSETAVVNVT
10 20 30
130 140 150 160 170 180
pF1KB3 YSSKDQARQALDKLNGFQLENFTLKVAYIPDEMAAQQNPLQQPRGRRGLGQRGSSRQGSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YSSKDQARQALDKLNGFQLENFTLKVAYIPDEMAAQQNPLQQPRGRRGLGQRGSSRQGSP
40 50 60 70 80 90
190 200 210 220 230 240
pF1KB3 GSVSKQKPCDLPLRLLVPTQFVGAIIGKEGATIRNITKQTQSKIDVHRKENAGAAEKSIT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GSVSKQKPCDLPLRLLVPTQFVGAIIGKEGATIRNITKQTQSKIDVHRKENAGAAEKSIT
100 110 120 130 140 150
250 260 270 280 290 300
pF1KB3 ILSTPEGTSAACKSILEIMHKEAQDIKFTEEIPLKILAHNNFVGRLIGKEGRNLKKIEQD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ILSTPEGTSAACKSILEIMHKEAQDIKFTEEIPLKILAHNNFVGRLIGKEGRNLKKIEQD
160 170 180 190 200 210
310 320 330 340 350 360
pF1KB3 TDTKITISPLQELTLYNPERTITVKGNVETCAKAEEEIMKKIRESYENDIASMNLQAHLI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TDTKITISPLQELTLYNPERTITVKGNVETCAKAEEEIMKKIRESYENDIASMNLQAHLI
220 230 240 250 260 270
370 380 390 400 410 420
pF1KB3 PGLNLNALGLFPPTSGMPPPTSGPPSAMTPPYPQFEQSETETVHLFIPALSVGAIIGKQG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PGLNLNALGLFPPTSGMPPPTSGPPSAMTPPYPQFEQSETETVHLFIPALSVGAIIGKQG
280 290 300 310 320 330
430 440 450 460 470 480
pF1KB3 QHIKQLSRFAGASIKIAPAEAPDAKVRMVIITGPPEAQFKAQGRIYGKIKEENFVSPKEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QHIKQLSRFAGASIKIAPAEAPDAKVRMVIITGPPEAQFKAQGRIYGKIKEENFVSPKEE
340 350 360 370 380 390
490 500 510 520 530 540
pF1KB3 VKLEAHIRVPSFAAGRVIGKGGKTVNELQNLSSAEVVVPRDQTPDENDQVVVKITGHFYA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VKLEAHIRVPSFAAGRVIGKGGKTVNELQNLSSAEVVVPRDQTPDENDQVVVKITGHFYA
400 410 420 430 440 450
550 560 570
pF1KB3 CQVAQRKIQEILTQVKQHQQQKALQSGPPQSRRK
::::::::::::::::::::::::::::::::::
XP_011 CQVAQRKIQEILTQVKQHQQQKALQSGPPQSRRK
460 470 480
>>XP_011513392 (OMIM: 608259) PREDICTED: insulin-like gr (471 aa)
initn: 2893 init1: 2893 opt: 2893 Z-score: 2294.9 bits: 434.3 E(85289): 4.4e-121
Smith-Waterman score: 2893; 99.8% identity (100.0% similar) in 446 aa overlap (134-579:26-471)
110 120 130 140 150 160
pF1KB3 YGVVESCEQVNTDSETAVVNVTYSSKDQARQALDKLNGFQLENFTLKVAYIPDEMAAQQN
.:::::::::::::::::::::::::::::
XP_011 MILPASAHHGFGNFRYEISRLIYSGRALDKLNGFQLENFTLKVAYIPDEMAAQQN
10 20 30 40 50
170 180 190 200 210 220
pF1KB3 PLQQPRGRRGLGQRGSSRQGSPGSVSKQKPCDLPLRLLVPTQFVGAIIGKEGATIRNITK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PLQQPRGRRGLGQRGSSRQGSPGSVSKQKPCDLPLRLLVPTQFVGAIIGKEGATIRNITK
60 70 80 90 100 110
230 240 250 260 270 280
pF1KB3 QTQSKIDVHRKENAGAAEKSITILSTPEGTSAACKSILEIMHKEAQDIKFTEEIPLKILA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QTQSKIDVHRKENAGAAEKSITILSTPEGTSAACKSILEIMHKEAQDIKFTEEIPLKILA
120 130 140 150 160 170
290 300 310 320 330 340
pF1KB3 HNNFVGRLIGKEGRNLKKIEQDTDTKITISPLQELTLYNPERTITVKGNVETCAKAEEEI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HNNFVGRLIGKEGRNLKKIEQDTDTKITISPLQELTLYNPERTITVKGNVETCAKAEEEI
180 190 200 210 220 230
350 360 370 380 390 400
pF1KB3 MKKIRESYENDIASMNLQAHLIPGLNLNALGLFPPTSGMPPPTSGPPSAMTPPYPQFEQS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MKKIRESYENDIASMNLQAHLIPGLNLNALGLFPPTSGMPPPTSGPPSAMTPPYPQFEQS
240 250 260 270 280 290
410 420 430 440 450 460
pF1KB3 ETETVHLFIPALSVGAIIGKQGQHIKQLSRFAGASIKIAPAEAPDAKVRMVIITGPPEAQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ETETVHLFIPALSVGAIIGKQGQHIKQLSRFAGASIKIAPAEAPDAKVRMVIITGPPEAQ
300 310 320 330 340 350
470 480 490 500 510 520
pF1KB3 FKAQGRIYGKIKEENFVSPKEEVKLEAHIRVPSFAAGRVIGKGGKTVNELQNLSSAEVVV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FKAQGRIYGKIKEENFVSPKEEVKLEAHIRVPSFAAGRVIGKGGKTVNELQNLSSAEVVV
360 370 380 390 400 410
530 540 550 560 570
pF1KB3 PRDQTPDENDQVVVKITGHFYACQVAQRKIQEILTQVKQHQQQKALQSGPPQSRRK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PRDQTPDENDQVVVKITGHFYACQVAQRKIQEILTQVKQHQQQKALQSGPPQSRRK
420 430 440 450 460 470
>>XP_011522503 (OMIM: 608288) PREDICTED: insulin-like gr (576 aa)
initn: 2811 init1: 1836 opt: 2817 Z-score: 2233.8 bits: 423.3 E(85289): 1.1e-117
Smith-Waterman score: 2817; 74.3% identity (89.9% similar) in 584 aa overlap (1-579:1-576)
10 20 30 40 50 60
pF1KB3 MNKLYIGNLSENAAPSDLESIFKDAKIPVSGPFLVKTGYAFVDCPDESWALKAIEALSGK
:::::::::.:...:.:::..: . :: :: ::::.:::::::::: ::.::::..:::
XP_011 MNKLYIGNLNESVTPADLEKVFAEHKISYSGQFLVKSGYAFVDCPDEHWAMKAIETFSGK
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB3 IELHGKPIEVEHSVPKRQRIRKLQIRNIPPHLQWEVLDSLLVQYGVVESCEQVNTDSETA
.::.:: .:.::::::.:: ::.:::::::.:.::::::::.:::.::.::::::.::::
XP_011 VELQGKRLEIEHSVPKKQRSRKIQIRNIPPQLRWEVLDSLLAQYGTVENCEQVNTESETA
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB3 VVNVTYSSKDQARQALDKLNGFQLENFTLKVAYIPDEMAAQQNPLQQPRGRRGLGQRGSS
:::::::...:.:::. :::: :::: .:::.:::::. :: .: . :: :.:.::.
XP_011 VVNVTYSNREQTRQAIMKLNGHQLENHALKVSYIPDEQIAQ-GPENGRRG--GFGSRGQP
130 140 150 160 170
190 200 210 220 230
pF1KB3 RQGSP---GSVSKQKPCDLPLRLLVPTQFVGAIIGKEGATIRNITKQTQSKIDVHRKENA
::::: :. .::. :.:::::::::.:::::::::::::::::::::::::::::::
XP_011 RQGSPVAAGAPAKQQQVDIPLRLLVPTQYVGAIIGKEGATIRNITKQTQSKIDVHRKENA
180 190 200 210 220 230
240 250 260 270 280 290
pF1KB3 GAAEKSITILSTPEGTSAACKSILEIMHKEAQDIKFTEEIPLKILAHNNFVGRLIGKEGR
:::::.:.. ::::: :.::: :::::::::.: : ..:.::::::::::::::::::::
XP_011 GAAEKAISVHSTPEGCSSACKMILEIMHKEAKDTKTADEVPLKILAHNNFVGRLIGKEGR
240 250 260 270 280 290
300 310 320 330 340 350
pF1KB3 NLKKIEQDTDTKITISPLQELTLYNPERTITVKGNVETCAKAEEEIMKKIRESYENDIAS
::::.::::.:::::: ::.:::::::::::::: .:.: .::.:::::.::.::::.:.
XP_011 NLKKVEQDTETKITISSLQDLTLYNPERTITVKGAIENCCRAEQEIMKKVREAYENDVAA
300 310 320 330 340 350
360 370 380 390 400 410
pF1KB3 MNLQAHLIPGLNLNALGLFPPTSGMPPPTSGPPSAMT--PPYPQFEQSETETVHLFIPAL
:.::.:::::::: :.:::: .:. :: :::..: :: .: : : :..::::
XP_011 MSLQSHLIPGLNLAAVGLFPASSSAVPP---PPSSVTGAAPYSSFMAPEQEMVQVFIPAQ
360 370 380 390 400 410
420 430 440 450 460 470
pF1KB3 SVGAIIGKQGQHIKQLSRFAGASIKIAPAEAPDAKVRMVIITGPPEAQFKAQGRIYGKIK
.:::::::.:::::::::::.::::::: :.::.::::::::::::::::::::::::.:
XP_011 AVGAIIGKKGQHIKQLSRFASASIKIAPPETPDSKVRMVIITGPPEAQFKAQGRIYGKLK
420 430 440 450 460 470
480 490 500 510 520 530
pF1KB3 EENFVSPKEEVKLEAHIRVPSFAAGRVIGKGGKTVNELQNLSSAEVVVPRDQTPDENDQV
:::: .::::::::.:::::. :::::::::::::::::::..:::::::::::::::::
XP_011 EENFFGPKEEVKLETHIRVPASAAGRVIGKGGKTVNELQNLTAAEVVVPRDQTPDENDQV
480 490 500 510 520 530
540 550 560 570
pF1KB3 VVKITGHFYACQVAQRKIQEILTQVKQHQQQKALQSGPPQSRRK
.::: ::::: :.:::::..::.:::: :.::. ::. :.:::
XP_011 IVKIIGHFYASQMAQRKIRDILAQVKQ-QHQKG-QSNQAQARRK
540 550 560 570
>>NP_006537 (OMIM: 608288) insulin-like growth factor 2 (577 aa)
initn: 2949 init1: 2709 opt: 2815 Z-score: 2232.2 bits: 423.0 E(85289): 1.4e-117
Smith-Waterman score: 2815; 74.4% identity (90.1% similar) in 585 aa overlap (1-579:1-577)
10 20 30 40 50 60
pF1KB3 MNKLYIGNLSENAAPSDLESIFKDAKIPVSGPFLVKTGYAFVDCPDESWALKAIEALSGK
:::::::::.:...:.:::..: . :: :: ::::.:::::::::: ::.::::..:::
NP_006 MNKLYIGNLNESVTPADLEKVFAEHKISYSGQFLVKSGYAFVDCPDEHWAMKAIETFSGK
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB3 IELHGKPIEVEHSVPKRQRIRKLQIRNIPPHLQWEVLDSLLVQYGVVESCEQVNTDSETA
.::.:: .:.::::::.:: ::.:::::::.:.::::::::.:::.::.::::::.::::
NP_006 VELQGKRLEIEHSVPKKQRSRKIQIRNIPPQLRWEVLDSLLAQYGTVENCEQVNTESETA
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB3 VVNVTYSSKDQARQALDKLNGFQLENFTLKVAYIPDEMAAQQNPLQQPRGRRGLGQRGSS
:::::::...:.:::. :::: :::: .:::.:::::. :: .: . :: :.:.::.
NP_006 VVNVTYSNREQTRQAIMKLNGHQLENHALKVSYIPDEQIAQ-GPENGRRG--GFGSRGQP
130 140 150 160 170
190 200 210 220 230
pF1KB3 RQGSP---GSVSKQKPCDLPLRLLVPTQFVGAIIGKEGATIRNITKQTQSKIDVHRKENA
::::: :. .::. :.:::::::::.:::::::::::::::::::::::::::::::
NP_006 RQGSPVAAGAPAKQQQVDIPLRLLVPTQYVGAIIGKEGATIRNITKQTQSKIDVHRKENA
180 190 200 210 220 230
240 250 260 270 280 290
pF1KB3 GAAEKSITILSTPEGTSAACKSILEIMHKEAQDIKFTEEIPLKILAHNNFVGRLIGKEGR
:::::.:.. ::::: :.::: :::::::::.: : ..:.::::::::::::::::::::
NP_006 GAAEKAISVHSTPEGCSSACKMILEIMHKEAKDTKTADEVPLKILAHNNFVGRLIGKEGR
240 250 260 270 280 290
300 310 320 330 340 350
pF1KB3 NLKKIEQDTDTKITISPLQELTLYNPERTITVKGNVETCAKAEEEIMKKIRESYENDIAS
::::.::::.:::::: ::.:::::::::::::: .:.: .::.:::::.::.::::.:.
NP_006 NLKKVEQDTETKITISSLQDLTLYNPERTITVKGAIENCCRAEQEIMKKVREAYENDVAA
300 310 320 330 340 350
360 370 380 390 400 410
pF1KB3 MNLQAHLIPGLNLNALGLFPPTSGMPPPTSGPPSAMT--PPYPQFEQS-ETETVHLFIPA
:.::.:::::::: :.:::: .:. :: :::..: :: .: :. : : :..::::
NP_006 MSLQSHLIPGLNLAAVGLFPASSSAVPP---PPSSVTGAAPYSSFMQAPEQEMVQVFIPA
360 370 380 390 400 410
420 430 440 450 460 470
pF1KB3 LSVGAIIGKQGQHIKQLSRFAGASIKIAPAEAPDAKVRMVIITGPPEAQFKAQGRIYGKI
.:::::::.:::::::::::.::::::: :.::.::::::::::::::::::::::::.
NP_006 QAVGAIIGKKGQHIKQLSRFASASIKIAPPETPDSKVRMVIITGPPEAQFKAQGRIYGKL
420 430 440 450 460 470
480 490 500 510 520 530
pF1KB3 KEENFVSPKEEVKLEAHIRVPSFAAGRVIGKGGKTVNELQNLSSAEVVVPRDQTPDENDQ
::::: .::::::::.:::::. :::::::::::::::::::..::::::::::::::::
NP_006 KEENFFGPKEEVKLETHIRVPASAAGRVIGKGGKTVNELQNLTAAEVVVPRDQTPDENDQ
480 490 500 510 520 530
540 550 560 570
pF1KB3 VVVKITGHFYACQVAQRKIQEILTQVKQHQQQKALQSGPPQSRRK
:.::: ::::: :.:::::..::.:::: :.::. ::. :.:::
NP_006 VIVKIIGHFYASQMAQRKIRDILAQVKQ-QHQKG-QSNQAQARRK
540 550 560 570
>>XP_016879511 (OMIM: 608288) PREDICTED: insulin-like gr (575 aa)
initn: 2767 init1: 1705 opt: 2789 Z-score: 2211.7 bits: 419.2 E(85289): 1.9e-116
Smith-Waterman score: 2789; 74.0% identity (89.7% similar) in 585 aa overlap (1-579:1-575)
10 20 30 40 50 60
pF1KB3 MNKLYIGNLSENAAPSDLESIFKDAKIPVSGPFLVKTGYAFVDCPDESWALKAIEALSGK
:::::::::.:...:.:::..: . :: :: ::::.:::::::::: ::.::::..:::
XP_016 MNKLYIGNLNESVTPADLEKVFAEHKISYSGQFLVKSGYAFVDCPDEHWAMKAIETFSGK
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB3 IELHGKPIEVEHSVPKRQRIRKLQIRNIPPHLQWEVLDSLLVQYGVVESCEQVNTDSETA
.::.:: .:.::::::.:: ::.:::::::.:.::::::::.:::.::.::::::.::::
XP_016 VELQGKRLEIEHSVPKKQRSRKIQIRNIPPQLRWEVLDSLLAQYGTVENCEQVNTESETA
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB3 VVNVTYSSKDQARQALDKLNGFQLENFTLKVAYIPDEMAAQQNPLQQPRGRRGLGQRGSS
:::::::...:.:::. :::: :::: .:::.:::::. :: .: . :: :.:.::.
XP_016 VVNVTYSNREQTRQAIMKLNGHQLENHALKVSYIPDEQIAQ-GPENGRRG--GFGSRGQP
130 140 150 160 170
190 200 210 220 230
pF1KB3 RQGSP---GSVSKQKPCDLPLRLLVPTQFVGAIIGKEGATIRNITKQTQSKIDVHRKENA
::::: :. .::. :.:::::::::.:::::::::::::::::::::::::::::::
XP_016 RQGSPVAAGAPAKQQQVDIPLRLLVPTQYVGAIIGKEGATIRNITKQTQSKIDVHRKENA
180 190 200 210 220 230
240 250 260 270 280 290
pF1KB3 GAAEKSITILSTPEGTSAACKSILEIMHKEAQDIKFTEEIPLKILAHNNFVGRLIGKEGR
:::::.:.. ::::: :.::: :::::::::.: : ..:.::::::::::::::::::::
XP_016 GAAEKAISVHSTPEGCSSACKMILEIMHKEAKDTKTADEVPLKILAHNNFVGRLIGKEGR
240 250 260 270 280 290
300 310 320 330 340 350
pF1KB3 NLKKIEQDTDTKITISPLQELTLYNPERTITVKGNVETCAKAEEEIMKKIRESYENDIAS
::::.::::.:::::: ::.:::::::::::::: .:.: .::.:::::.::.::::.:.
XP_016 NLKKVEQDTETKITISSLQDLTLYNPERTITVKGAIENCCRAEQEIMKKVREAYENDVAA
300 310 320 330 340 350
360 370 380 390 400 410
pF1KB3 MNLQAHLIPGLNLNALGLFPPTSGMPPPTSGPPSAMT--PPYPQFEQS-ETETVHLFIPA
:. .:::::::: :.:::: .:. :: :::..: :: .: :. : : :..::::
XP_016 MS--SHLIPGLNLAAVGLFPASSSAVPP---PPSSVTGAAPYSSFMQAPEQEMVQVFIPA
360 370 380 390 400 410
420 430 440 450 460 470
pF1KB3 LSVGAIIGKQGQHIKQLSRFAGASIKIAPAEAPDAKVRMVIITGPPEAQFKAQGRIYGKI
.:::::::.:::::::::::.::::::: :.::.::::::::::::::::::::::::.
XP_016 QAVGAIIGKKGQHIKQLSRFASASIKIAPPETPDSKVRMVIITGPPEAQFKAQGRIYGKL
420 430 440 450 460 470
480 490 500 510 520 530
pF1KB3 KEENFVSPKEEVKLEAHIRVPSFAAGRVIGKGGKTVNELQNLSSAEVVVPRDQTPDENDQ
::::: .::::::::.:::::. :::::::::::::::::::..::::::::::::::::
XP_016 KEENFFGPKEEVKLETHIRVPASAAGRVIGKGGKTVNELQNLTAAEVVVPRDQTPDENDQ
480 490 500 510 520 530
540 550 560 570
pF1KB3 VVVKITGHFYACQVAQRKIQEILTQVKQHQQQKALQSGPPQSRRK
:.::: ::::: :.:::::..::.:::: :.::. ::. :.:::
XP_016 VIVKIIGHFYASQMAQRKIRDILAQVKQ-QHQKG-QSNQAQARRK
540 550 560 570
>>XP_011513393 (OMIM: 608259) PREDICTED: insulin-like gr (422 aa)
initn: 2744 init1: 2744 opt: 2744 Z-score: 2177.9 bits: 412.5 E(85289): 1.4e-114
Smith-Waterman score: 2744; 100.0% identity (100.0% similar) in 422 aa overlap (158-579:1-422)
130 140 150 160 170 180
pF1KB3 SKDQARQALDKLNGFQLENFTLKVAYIPDEMAAQQNPLQQPRGRRGLGQRGSSRQGSPGS
::::::::::::::::::::::::::::::
XP_011 MAAQQNPLQQPRGRRGLGQRGSSRQGSPGS
10 20 30
190 200 210 220 230 240
pF1KB3 VSKQKPCDLPLRLLVPTQFVGAIIGKEGATIRNITKQTQSKIDVHRKENAGAAEKSITIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VSKQKPCDLPLRLLVPTQFVGAIIGKEGATIRNITKQTQSKIDVHRKENAGAAEKSITIL
40 50 60 70 80 90
250 260 270 280 290 300
pF1KB3 STPEGTSAACKSILEIMHKEAQDIKFTEEIPLKILAHNNFVGRLIGKEGRNLKKIEQDTD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 STPEGTSAACKSILEIMHKEAQDIKFTEEIPLKILAHNNFVGRLIGKEGRNLKKIEQDTD
100 110 120 130 140 150
310 320 330 340 350 360
pF1KB3 TKITISPLQELTLYNPERTITVKGNVETCAKAEEEIMKKIRESYENDIASMNLQAHLIPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TKITISPLQELTLYNPERTITVKGNVETCAKAEEEIMKKIRESYENDIASMNLQAHLIPG
160 170 180 190 200 210
370 380 390 400 410 420
pF1KB3 LNLNALGLFPPTSGMPPPTSGPPSAMTPPYPQFEQSETETVHLFIPALSVGAIIGKQGQH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LNLNALGLFPPTSGMPPPTSGPPSAMTPPYPQFEQSETETVHLFIPALSVGAIIGKQGQH
220 230 240 250 260 270
430 440 450 460 470 480
pF1KB3 IKQLSRFAGASIKIAPAEAPDAKVRMVIITGPPEAQFKAQGRIYGKIKEENFVSPKEEVK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IKQLSRFAGASIKIAPAEAPDAKVRMVIITGPPEAQFKAQGRIYGKIKEENFVSPKEEVK
280 290 300 310 320 330
490 500 510 520 530 540
pF1KB3 LEAHIRVPSFAAGRVIGKGGKTVNELQNLSSAEVVVPRDQTPDENDQVVVKITGHFYACQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LEAHIRVPSFAAGRVIGKGGKTVNELQNLSSAEVVVPRDQTPDENDQVVVKITGHFYACQ
340 350 360 370 380 390
550 560 570
pF1KB3 VAQRKIQEILTQVKQHQQQKALQSGPPQSRRK
::::::::::::::::::::::::::::::::
XP_011 VAQRKIQEILTQVKQHQQQKALQSGPPQSRRK
400 410 420
>>XP_006715702 (OMIM: 608259) PREDICTED: insulin-like gr (422 aa)
initn: 2744 init1: 2744 opt: 2744 Z-score: 2177.9 bits: 412.5 E(85289): 1.4e-114
Smith-Waterman score: 2744; 100.0% identity (100.0% similar) in 422 aa overlap (158-579:1-422)
130 140 150 160 170 180
pF1KB3 SKDQARQALDKLNGFQLENFTLKVAYIPDEMAAQQNPLQQPRGRRGLGQRGSSRQGSPGS
::::::::::::::::::::::::::::::
XP_006 MAAQQNPLQQPRGRRGLGQRGSSRQGSPGS
10 20 30
190 200 210 220 230 240
pF1KB3 VSKQKPCDLPLRLLVPTQFVGAIIGKEGATIRNITKQTQSKIDVHRKENAGAAEKSITIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 VSKQKPCDLPLRLLVPTQFVGAIIGKEGATIRNITKQTQSKIDVHRKENAGAAEKSITIL
40 50 60 70 80 90
250 260 270 280 290 300
pF1KB3 STPEGTSAACKSILEIMHKEAQDIKFTEEIPLKILAHNNFVGRLIGKEGRNLKKIEQDTD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 STPEGTSAACKSILEIMHKEAQDIKFTEEIPLKILAHNNFVGRLIGKEGRNLKKIEQDTD
100 110 120 130 140 150
310 320 330 340 350 360
pF1KB3 TKITISPLQELTLYNPERTITVKGNVETCAKAEEEIMKKIRESYENDIASMNLQAHLIPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 TKITISPLQELTLYNPERTITVKGNVETCAKAEEEIMKKIRESYENDIASMNLQAHLIPG
160 170 180 190 200 210
370 380 390 400 410 420
pF1KB3 LNLNALGLFPPTSGMPPPTSGPPSAMTPPYPQFEQSETETVHLFIPALSVGAIIGKQGQH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LNLNALGLFPPTSGMPPPTSGPPSAMTPPYPQFEQSETETVHLFIPALSVGAIIGKQGQH
220 230 240 250 260 270
430 440 450 460 470 480
pF1KB3 IKQLSRFAGASIKIAPAEAPDAKVRMVIITGPPEAQFKAQGRIYGKIKEENFVSPKEEVK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 IKQLSRFAGASIKIAPAEAPDAKVRMVIITGPPEAQFKAQGRIYGKIKEENFVSPKEEVK
280 290 300 310 320 330
490 500 510 520 530 540
pF1KB3 LEAHIRVPSFAAGRVIGKGGKTVNELQNLSSAEVVVPRDQTPDENDQVVVKITGHFYACQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LEAHIRVPSFAAGRVIGKGGKTVNELQNLSSAEVVVPRDQTPDENDQVVVKITGHFYACQ
340 350 360 370 380 390
550 560 570
pF1KB3 VAQRKIQEILTQVKQHQQQKALQSGPPQSRRK
::::::::::::::::::::::::::::::::
XP_006 VAQRKIQEILTQVKQHQQQKALQSGPPQSRRK
400 410 420
579 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sat Nov 5 05:27:09 2016 done: Sat Nov 5 05:27:11 2016
Total Scan time: 10.860 Total Display time: 0.140
Function used was FASTA [36.3.4 Apr, 2011]