Result of FASTA (omim) for
pFN21AE0927
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE0927, 363 aa
1>>>pF1KE0927 363 - 363 aa - 363 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.5194+/-0.000408; mu= 14.9006+/- 0.025
mean_var=67.3076+/-13.748, 0's: 0 Z-trim(112.9): 18 B-trim: 649 in 1/48
Lambda= 0.156330
statistics sampled from 22009 (22021) to 22009 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.648), E-opt: 0.2 (0.258), width: 16
Scan time: 8.200
The best scores are: opt bits E(85289)
NP_000013 (OMIM: 102700,608958) adenosine deaminas ( 363) 2430 557.1 2.1e-158
NP_001308980 (OMIM: 102700,608958) adenosine deami ( 339) 1365 316.9 4.1e-86
NP_001308979 (OMIM: 102700,608958) adenosine deami ( 228) 1356 314.8 1.2e-85
NP_803124 (OMIM: 182410,607575,615688) adenosine d ( 270) 181 49.9 8.2e-06
XP_006724143 (OMIM: 182410,607575,615688) PREDICTE ( 283) 181 49.9 8.5e-06
NP_001269158 (OMIM: 182410,607575,615688) adenosin ( 391) 181 49.9 1.1e-05
NP_001269157 (OMIM: 182410,607575,615688) adenosin ( 469) 181 50.0 1.3e-05
NP_001269156 (OMIM: 182410,607575,615688) adenosin ( 469) 181 50.0 1.3e-05
XP_011544435 (OMIM: 182410,607575,615688) PREDICTE ( 511) 181 50.0 1.4e-05
NP_001269154 (OMIM: 182410,607575,615688) adenosin ( 511) 181 50.0 1.4e-05
NP_001269155 (OMIM: 182410,607575,615688) adenosin ( 511) 181 50.0 1.4e-05
>>NP_000013 (OMIM: 102700,608958) adenosine deaminase is (363 aa)
initn: 2430 init1: 2430 opt: 2430 Z-score: 2964.7 bits: 557.1 E(85289): 2.1e-158
Smith-Waterman score: 2430; 100.0% identity (100.0% similar) in 363 aa overlap (1-363:1-363)
10 20 30 40 50 60
pF1KE0 MAQTPAFDKPKVELHVHLDGSIKPETILYYGRRRGIALPANTAEGLLNVIGMDKPLTLPD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 MAQTPAFDKPKVELHVHLDGSIKPETILYYGRRRGIALPANTAEGLLNVIGMDKPLTLPD
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 FLAKFDYYMPAIAGCREAIKRIAYEFVEMKAKEGVVYVEVRYSPHLLANSKVEPIPWNQA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 FLAKFDYYMPAIAGCREAIKRIAYEFVEMKAKEGVVYVEVRYSPHLLANSKVEPIPWNQA
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE0 EGDLTPDEVVALVGQGLQEGERDFGVKARSILCCMRHQPNWSPKVVELCKKYQQQTVVAI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 EGDLTPDEVVALVGQGLQEGERDFGVKARSILCCMRHQPNWSPKVVELCKKYQQQTVVAI
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE0 DLAGDETIPGSSLLPGHVQAYQEAVKSGIHRTVHAGEVGSAEVVKEAVDILKTERLGHGY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 DLAGDETIPGSSLLPGHVQAYQEAVKSGIHRTVHAGEVGSAEVVKEAVDILKTERLGHGY
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE0 HTLEDQALYNRLRQENMHFEICPWSSYLTGAWKPDTEHAVIRLKNDQANYSLNTDDPLIF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 HTLEDQALYNRLRQENMHFEICPWSSYLTGAWKPDTEHAVIRLKNDQANYSLNTDDPLIF
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE0 KSTLDTDYQMTKRDMGFTEEEFKRLNINAAKSSFLPEDEKRELLDLLYKAYGMPPSASAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 KSTLDTDYQMTKRDMGFTEEEFKRLNINAAKSSFLPEDEKRELLDLLYKAYGMPPSASAG
310 320 330 340 350 360
pF1KE0 QNL
:::
NP_000 QNL
>>NP_001308980 (OMIM: 102700,608958) adenosine deaminase (339 aa)
initn: 1365 init1: 1365 opt: 1365 Z-score: 1667.0 bits: 316.9 E(85289): 4.1e-86
Smith-Waterman score: 2225; 93.4% identity (93.4% similar) in 363 aa overlap (1-363:1-339)
10 20 30 40 50 60
pF1KE0 MAQTPAFDKPKVELHVHLDGSIKPETILYYGRRRGIALPANTAEGLLNVIGMDKPLTLPD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MAQTPAFDKPKVELHVHLDGSIKPETILYYGRRRGIALPANTAEGLLNVIGMDKPLTLPD
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 FLAKFDYYMPAIAGCREAIKRIAYEFVEMKAKEGVVYVEVRYSPHLLANSKVEPIPWNQA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FLAKFDYYMPAIAGCREAIKRIAYEFVEMKAKEGVVYVEVRYSPHLLANSKVEPIPWNQA
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE0 EGDLTPDEVVALVGQGLQEGERDFGVKARSILCCMRHQPNWSPKVVELCKKYQQQTVVAI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EGDLTPDEVVALVGQGLQEGERDFGVKARSILCCMRHQPNWSPKVVELCKKYQQQTVVAI
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE0 DLAGDETIPGSSLLPGHVQAYQEAVKSGIHRTVHAGEVGSAEVVKEAVDILKTERLGHGY
:::::::::::::::::::::: ::::::::::::::
NP_001 DLAGDETIPGSSLLPGHVQAYQ------------------------AVDILKTERLGHGY
190 200 210
250 260 270 280 290 300
pF1KE0 HTLEDQALYNRLRQENMHFEICPWSSYLTGAWKPDTEHAVIRLKNDQANYSLNTDDPLIF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HTLEDQALYNRLRQENMHFEICPWSSYLTGAWKPDTEHAVIRLKNDQANYSLNTDDPLIF
220 230 240 250 260 270
310 320 330 340 350 360
pF1KE0 KSTLDTDYQMTKRDMGFTEEEFKRLNINAAKSSFLPEDEKRELLDLLYKAYGMPPSASAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KSTLDTDYQMTKRDMGFTEEEFKRLNINAAKSSFLPEDEKRELLDLLYKAYGMPPSASAG
280 290 300 310 320 330
pF1KE0 QNL
:::
NP_001 QNL
>>NP_001308979 (OMIM: 102700,608958) adenosine deaminase (228 aa)
initn: 1356 init1: 1356 opt: 1356 Z-score: 1658.7 bits: 314.8 E(85289): 1.2e-85
Smith-Waterman score: 1356; 100.0% identity (100.0% similar) in 204 aa overlap (160-363:25-228)
130 140 150 160 170 180
pF1KE0 VALVGQGLQEGERDFGVKARSILCCMRHQPNWSPKVVELCKKYQQQTVVAIDLAGDETIP
::::::::::::::::::::::::::::::
NP_001 MWRCGTVRTCWPTPKWSQSPGTRLNWSPKVVELCKKYQQQTVVAIDLAGDETIP
10 20 30 40 50
190 200 210 220 230 240
pF1KE0 GSSLLPGHVQAYQEAVKSGIHRTVHAGEVGSAEVVKEAVDILKTERLGHGYHTLEDQALY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GSSLLPGHVQAYQEAVKSGIHRTVHAGEVGSAEVVKEAVDILKTERLGHGYHTLEDQALY
60 70 80 90 100 110
250 260 270 280 290 300
pF1KE0 NRLRQENMHFEICPWSSYLTGAWKPDTEHAVIRLKNDQANYSLNTDDPLIFKSTLDTDYQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NRLRQENMHFEICPWSSYLTGAWKPDTEHAVIRLKNDQANYSLNTDDPLIFKSTLDTDYQ
120 130 140 150 160 170
310 320 330 340 350 360
pF1KE0 MTKRDMGFTEEEFKRLNINAAKSSFLPEDEKRELLDLLYKAYGMPPSASAGQNL
::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MTKRDMGFTEEEFKRLNINAAKSSFLPEDEKRELLDLLYKAYGMPPSASAGQNL
180 190 200 210 220
>>NP_803124 (OMIM: 182410,607575,615688) adenosine deami (270 aa)
initn: 92 init1: 92 opt: 181 Z-score: 225.4 bits: 49.9 E(85289): 8.2e-06
Smith-Waterman score: 181; 27.0% identity (56.2% similar) in 185 aa overlap (176-349:76-258)
150 160 170 180 190 200
pF1KE0 VKARSILCCMRHQPNWSPKVVELCKKYQQQTVVA-IDLAGDETIPGSSLLPGHVQAYQEA
:::: .::.: : : :: . .: .
NP_803 KIIYSDHRSKDVAVIAESIRMAMGLRIKFPTVVAGFDLVGHEDT-GHSL-HDYKEALMIP
50 60 70 80 90 100
210 220 230 240 250
pF1KE0 VKSGIH--RTVHAGEVG--SAEVVKEAVD--ILKTERLGHGYHTLEDQALYNRLRQENMH
.:.:.. ::::. .. . .. .: .:.: :.:::. . :. . ....
NP_803 AKDGVKLPYFFHAGETDWQGTSIDRNILDALMLNTTRIGHGFALSKHPAVRTYSWKKDIP
110 120 130 140 150 160
260 270 280 290 300 310
pF1KE0 FEICPWSSYLTGAWKPDTEHAVIRLKNDQANYSLNTDDPLIFKST-LDTDYQMTKRDMGF
.:.:: :. . . .: : : . ...::: .: . :. :. . .:
NP_803 IEVCPISNQVLKLVSDLRNHPVATLMATGHPMVISSDDPAMFGAKGLSYDFYEVFMGIGG
170 180 190 200 210 220
320 330 340 350 360
pF1KE0 TEEEF---KRLNINAAKSSFLPEDEKRELLDLLYKAYGMPPSASAGQNL
. .. :.: .:. : : : :.:: .... :
NP_803 MKADLRTLKQLAMNSIKYSTLLESEKNTFMEIWKKRWDKFIADVATK
230 240 250 260 270
>>XP_006724143 (OMIM: 182410,607575,615688) PREDICTED: a (283 aa)
initn: 92 init1: 92 opt: 181 Z-score: 225.0 bits: 49.9 E(85289): 8.5e-06
Smith-Waterman score: 187; 25.5% identity (54.2% similar) in 216 aa overlap (150-349:58-271)
120 130 140 150 160 170
pF1KE0 AEGDLTPDEVVALVGQGLQEGERDFGVKARSILCCMRHQPNWSPKVVELCK-----KYQQ
: : :. :. . ..: . . .
XP_006 GKRDLHTWGWPSPARRVCSGVCALSVLGTVSWLLCLSHRSKDVAVIAESIRMAMGLRIKF
30 40 50 60 70 80
180 190 200 210 220
pF1KE0 QTVVA-IDLAGDETIPGSSLLPGHVQAYQEAVKSGIH--RTVHAGEVG--SAEVVKEAVD
:::: .::.: : : :: . .: . .:.:.. ::::. .. . .. .:
XP_006 PTVVAGFDLVGHEDT-GHSL-HDYKEALMIPAKDGVKLPYFFHAGETDWQGTSIDRNILD
90 100 110 120 130 140
230 240 250 260 270 280
pF1KE0 --ILKTERLGHGYHTLEDQALYNRLRQENMHFEICPWSSYLTGAWKPDTEHAVIRLKNDQ
.:.: :.:::. . :. . .... .:.:: :. . . .: : :
XP_006 ALMLNTTRIGHGFALSKHPAVRTYSWKKDIPIEVCPISNQVLKLVSDLRNHPVATLMATG
150 160 170 180 190 200
290 300 310 320 330 340
pF1KE0 ANYSLNTDDPLIFKST-LDTDYQMTKRDMGFTEEEF---KRLNINAAKSSFLPEDEKREL
. ...::: .: . :. :. . .: . .. :.: .:. : : : :.:: .
XP_006 HPMVISSDDPAMFGAKGLSYDFYEVFMGIGGMKADLRTLKQLAMNSIKYSTLLESEKNTF
210 220 230 240 250 260
350 360
pF1KE0 LDLLYKAYGMPPSASAGQNL
... :
XP_006 MEIWKKRWDKFIADVATK
270 280
>>NP_001269158 (OMIM: 182410,607575,615688) adenosine de (391 aa)
initn: 92 init1: 92 opt: 181 Z-score: 222.9 bits: 49.9 E(85289): 1.1e-05
Smith-Waterman score: 181; 27.0% identity (56.2% similar) in 185 aa overlap (176-349:197-379)
150 160 170 180 190 200
pF1KE0 VKARSILCCMRHQPNWSPKVVELCKKYQQQTVVA-IDLAGDETIPGSSLLPGHVQAYQEA
:::: .::.: : : :: . .: .
NP_001 KIIYSDHRSKDVAVIAESIRMAMGLRIKFPTVVAGFDLVGHEDT-GHSL-HDYKEALMIP
170 180 190 200 210 220
210 220 230 240 250
pF1KE0 VKSGIH--RTVHAGEVG--SAEVVKEAVD--ILKTERLGHGYHTLEDQALYNRLRQENMH
.:.:.. ::::. .. . .. .: .:.: :.:::. . :. . ....
NP_001 AKDGVKLPYFFHAGETDWQGTSIDRNILDALMLNTTRIGHGFALSKHPAVRTYSWKKDIP
230 240 250 260 270 280
260 270 280 290 300 310
pF1KE0 FEICPWSSYLTGAWKPDTEHAVIRLKNDQANYSLNTDDPLIFKST-LDTDYQMTKRDMGF
.:.:: :. . . .: : : . ...::: .: . :. :. . .:
NP_001 IEVCPISNQVLKLVSDLRNHPVATLMATGHPMVISSDDPAMFGAKGLSYDFYEVFMGIGG
290 300 310 320 330 340
320 330 340 350 360
pF1KE0 TEEEF---KRLNINAAKSSFLPEDEKRELLDLLYKAYGMPPSASAGQNL
. .. :.: .:. : : : :.:: .... :
NP_001 MKADLRTLKQLAMNSIKYSTLLESEKNTFMEIWKKRWDKFIADVATK
350 360 370 380 390
>>NP_001269157 (OMIM: 182410,607575,615688) adenosine de (469 aa)
initn: 92 init1: 92 opt: 181 Z-score: 221.6 bits: 50.0 E(85289): 1.3e-05
Smith-Waterman score: 181; 27.0% identity (56.2% similar) in 185 aa overlap (176-349:275-457)
150 160 170 180 190 200
pF1KE0 VKARSILCCMRHQPNWSPKVVELCKKYQQQTVVA-IDLAGDETIPGSSLLPGHVQAYQEA
:::: .::.: : : :: . .: .
NP_001 KIIYSDHRSKDVAVIAESIRMAMGLRIKFPTVVAGFDLVGHEDT-GHSL-HDYKEALMIP
250 260 270 280 290 300
210 220 230 240 250
pF1KE0 VKSGIH--RTVHAGEVG--SAEVVKEAVD--ILKTERLGHGYHTLEDQALYNRLRQENMH
.:.:.. ::::. .. . .. .: .:.: :.:::. . :. . ....
NP_001 AKDGVKLPYFFHAGETDWQGTSIDRNILDALMLNTTRIGHGFALSKHPAVRTYSWKKDIP
310 320 330 340 350 360
260 270 280 290 300 310
pF1KE0 FEICPWSSYLTGAWKPDTEHAVIRLKNDQANYSLNTDDPLIFKST-LDTDYQMTKRDMGF
.:.:: :. . . .: : : . ...::: .: . :. :. . .:
NP_001 IEVCPISNQVLKLVSDLRNHPVATLMATGHPMVISSDDPAMFGAKGLSYDFYEVFMGIGG
370 380 390 400 410 420
320 330 340 350 360
pF1KE0 TEEEF---KRLNINAAKSSFLPEDEKRELLDLLYKAYGMPPSASAGQNL
. .. :.: .:. : : : :.:: .... :
NP_001 MKADLRTLKQLAMNSIKYSTLLESEKNTFMEIWKKRWDKFIADVATK
430 440 450 460
>>NP_001269156 (OMIM: 182410,607575,615688) adenosine de (469 aa)
initn: 92 init1: 92 opt: 181 Z-score: 221.6 bits: 50.0 E(85289): 1.3e-05
Smith-Waterman score: 181; 27.0% identity (56.2% similar) in 185 aa overlap (176-349:275-457)
150 160 170 180 190 200
pF1KE0 VKARSILCCMRHQPNWSPKVVELCKKYQQQTVVA-IDLAGDETIPGSSLLPGHVQAYQEA
:::: .::.: : : :: . .: .
NP_001 KIIYSDHRSKDVAVIAESIRMAMGLRIKFPTVVAGFDLVGHEDT-GHSL-HDYKEALMIP
250 260 270 280 290 300
210 220 230 240 250
pF1KE0 VKSGIH--RTVHAGEVG--SAEVVKEAVD--ILKTERLGHGYHTLEDQALYNRLRQENMH
.:.:.. ::::. .. . .. .: .:.: :.:::. . :. . ....
NP_001 AKDGVKLPYFFHAGETDWQGTSIDRNILDALMLNTTRIGHGFALSKHPAVRTYSWKKDIP
310 320 330 340 350 360
260 270 280 290 300 310
pF1KE0 FEICPWSSYLTGAWKPDTEHAVIRLKNDQANYSLNTDDPLIFKST-LDTDYQMTKRDMGF
.:.:: :. . . .: : : . ...::: .: . :. :. . .:
NP_001 IEVCPISNQVLKLVSDLRNHPVATLMATGHPMVISSDDPAMFGAKGLSYDFYEVFMGIGG
370 380 390 400 410 420
320 330 340 350 360
pF1KE0 TEEEF---KRLNINAAKSSFLPEDEKRELLDLLYKAYGMPPSASAGQNL
. .. :.: .:. : : : :.:: .... :
NP_001 MKADLRTLKQLAMNSIKYSTLLESEKNTFMEIWKKRWDKFIADVATK
430 440 450 460
>>XP_011544435 (OMIM: 182410,607575,615688) PREDICTED: a (511 aa)
initn: 92 init1: 92 opt: 181 Z-score: 221.1 bits: 50.0 E(85289): 1.4e-05
Smith-Waterman score: 181; 27.0% identity (56.2% similar) in 185 aa overlap (176-349:317-499)
150 160 170 180 190 200
pF1KE0 VKARSILCCMRHQPNWSPKVVELCKKYQQQTVVA-IDLAGDETIPGSSLLPGHVQAYQEA
:::: .::.: : : :: . .: .
XP_011 KIIYSDHRSKDVAVIAESIRMAMGLRIKFPTVVAGFDLVGHEDT-GHSL-HDYKEALMIP
290 300 310 320 330 340
210 220 230 240 250
pF1KE0 VKSGIH--RTVHAGEVG--SAEVVKEAVD--ILKTERLGHGYHTLEDQALYNRLRQENMH
.:.:.. ::::. .. . .. .: .:.: :.:::. . :. . ....
XP_011 AKDGVKLPYFFHAGETDWQGTSIDRNILDALMLNTTRIGHGFALSKHPAVRTYSWKKDIP
350 360 370 380 390 400
260 270 280 290 300 310
pF1KE0 FEICPWSSYLTGAWKPDTEHAVIRLKNDQANYSLNTDDPLIFKST-LDTDYQMTKRDMGF
.:.:: :. . . .: : : . ...::: .: . :. :. . .:
XP_011 IEVCPISNQVLKLVSDLRNHPVATLMATGHPMVISSDDPAMFGAKGLSYDFYEVFMGIGG
410 420 430 440 450 460
320 330 340 350 360
pF1KE0 TEEEF---KRLNINAAKSSFLPEDEKRELLDLLYKAYGMPPSASAGQNL
. .. :.: .:. : : : :.:: .... :
XP_011 MKADLRTLKQLAMNSIKYSTLLESEKNTFMEIWKKRWDKFIADVATK
470 480 490 500 510
>>NP_001269154 (OMIM: 182410,607575,615688) adenosine de (511 aa)
initn: 92 init1: 92 opt: 181 Z-score: 221.1 bits: 50.0 E(85289): 1.4e-05
Smith-Waterman score: 181; 27.0% identity (56.2% similar) in 185 aa overlap (176-349:317-499)
150 160 170 180 190 200
pF1KE0 VKARSILCCMRHQPNWSPKVVELCKKYQQQTVVA-IDLAGDETIPGSSLLPGHVQAYQEA
:::: .::.: : : :: . .: .
NP_001 KIIYSDHRSKDVAVIAESIRMAMGLRIKFPTVVAGFDLVGHEDT-GHSL-HDYKEALMIP
290 300 310 320 330 340
210 220 230 240 250
pF1KE0 VKSGIH--RTVHAGEVG--SAEVVKEAVD--ILKTERLGHGYHTLEDQALYNRLRQENMH
.:.:.. ::::. .. . .. .: .:.: :.:::. . :. . ....
NP_001 AKDGVKLPYFFHAGETDWQGTSIDRNILDALMLNTTRIGHGFALSKHPAVRTYSWKKDIP
350 360 370 380 390 400
260 270 280 290 300 310
pF1KE0 FEICPWSSYLTGAWKPDTEHAVIRLKNDQANYSLNTDDPLIFKST-LDTDYQMTKRDMGF
.:.:: :. . . .: : : . ...::: .: . :. :. . .:
NP_001 IEVCPISNQVLKLVSDLRNHPVATLMATGHPMVISSDDPAMFGAKGLSYDFYEVFMGIGG
410 420 430 440 450 460
320 330 340 350 360
pF1KE0 TEEEF---KRLNINAAKSSFLPEDEKRELLDLLYKAYGMPPSASAGQNL
. .. :.: .:. : : : :.:: .... :
NP_001 MKADLRTLKQLAMNSIKYSTLLESEKNTFMEIWKKRWDKFIADVATK
470 480 490 500 510
363 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sat Nov 5 04:33:11 2016 done: Sat Nov 5 04:33:13 2016
Total Scan time: 8.200 Total Display time: 0.000
Function used was FASTA [36.3.4 Apr, 2011]