Result of FASTA (omim) for
pFN21AE0907
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE0907, 217 aa
1>>>pF1KE0907 217 - 217 aa - 217 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.4090+/-0.000295; mu= 13.2220+/- 0.019
mean_var=58.8153+/-11.818, 0's: 0 Z-trim(117.3): 28 B-trim: 82 in 1/56
Lambda= 0.167236
statistics sampled from 29245 (29273) to 29245 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.722), E-opt: 0.2 (0.343), width: 16
Scan time: 6.270
The best scores are: opt bits E(85289)
NP_001959 (OMIM: 133440,615091) eukaryotic transla ( 217) 1498 369.1 3.1e-102
NP_001124150 (OMIM: 133440,615091) eukaryotic tran ( 237) 1460 360.0 1.9e-99
NP_001317946 (OMIM: 133440,615091) eukaryotic tran ( 245) 1460 360.0 2e-99
NP_001124151 (OMIM: 133440,615091) eukaryotic tran ( 248) 941 234.7 9.9e-62
NP_001263265 (OMIM: 605895) eukaryotic translation ( 234) 440 113.9 2.3e-25
NP_001317131 (OMIM: 605895) eukaryotic translation ( 240) 439 113.6 2.8e-25
NP_004837 (OMIM: 605895) eukaryotic translation in ( 245) 439 113.6 2.8e-25
NP_001269887 (OMIM: 605895) eukaryotic translation ( 236) 432 111.9 8.8e-25
NP_001263266 (OMIM: 605895) eukaryotic translation ( 189) 370 96.9 2.3e-20
NP_001317130 (OMIM: 605895) eukaryotic translation ( 200) 369 96.7 2.9e-20
NP_001317132 (OMIM: 605895) eukaryotic translation ( 191) 362 95.0 8.9e-20
NP_001128123 (OMIM: 609896) eukaryotic translation ( 224) 280 75.2 9.2e-14
NP_001269815 (OMIM: 609896) eukaryotic translation ( 118) 175 49.8 2.2e-06
XP_016861770 (OMIM: 609896) PREDICTED: eukaryotic ( 118) 175 49.8 2.2e-06
NP_775495 (OMIM: 609896) eukaryotic translation in ( 118) 175 49.8 2.2e-06
NP_001128121 (OMIM: 609896) eukaryotic translation ( 118) 175 49.8 2.2e-06
XP_016861769 (OMIM: 609896) PREDICTED: eukaryotic ( 118) 175 49.8 2.2e-06
XP_016861768 (OMIM: 609896) PREDICTED: eukaryotic ( 118) 175 49.8 2.2e-06
XP_016861771 (OMIM: 609896) PREDICTED: eukaryotic ( 118) 175 49.8 2.2e-06
XP_016861767 (OMIM: 609896) PREDICTED: eukaryotic ( 118) 175 49.8 2.2e-06
NP_001128122 (OMIM: 609896) eukaryotic translation ( 118) 175 49.8 2.2e-06
>>NP_001959 (OMIM: 133440,615091) eukaryotic translation (217 aa)
initn: 1498 init1: 1498 opt: 1498 Z-score: 1956.4 bits: 369.1 E(85289): 3.1e-102
Smith-Waterman score: 1498; 100.0% identity (100.0% similar) in 217 aa overlap (1-217:1-217)
10 20 30 40 50 60
pF1KE0 MATVEPETTPTPNPPTTEEEKTESNQEVANPEHYIKHPLQNRWALWFFKNDKSKTWQANL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MATVEPETTPTPNPPTTEEEKTESNQEVANPEHYIKHPLQNRWALWFFKNDKSKTWQANL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 RLISKFDTVEDFWALYNHIQLSSNLMPGCDYSLFKDGIEPMWEDEKNKRGGRWLITLNKQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RLISKFDTVEDFWALYNHIQLSSNLMPGCDYSLFKDGIEPMWEDEKNKRGGRWLITLNKQ
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE0 QRRSDLDRFWLETLLCLIGESFDDYSDDVCGAVVNVRAKGDKIAIWTTECENREAVTHIG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QRRSDLDRFWLETLLCLIGESFDDYSDDVCGAVVNVRAKGDKIAIWTTECENREAVTHIG
130 140 150 160 170 180
190 200 210
pF1KE0 RVYKERLGLPPKIVIGYQSHADTATKSGSTTKNRFVV
:::::::::::::::::::::::::::::::::::::
NP_001 RVYKERLGLPPKIVIGYQSHADTATKSGSTTKNRFVV
190 200 210
>>NP_001124150 (OMIM: 133440,615091) eukaryotic translat (237 aa)
initn: 1460 init1: 1460 opt: 1460 Z-score: 1906.3 bits: 360.0 E(85289): 1.9e-99
Smith-Waterman score: 1460; 100.0% identity (100.0% similar) in 211 aa overlap (7-217:27-237)
10 20 30 40
pF1KE0 MATVEPETTPTPNPPTTEEEKTESNQEVANPEHYIKHPLQ
::::::::::::::::::::::::::::::::::
NP_001 MLDLTSRGQVGTSRRMAEAACSAHFLETTPTPNPPTTEEEKTESNQEVANPEHYIKHPLQ
10 20 30 40 50 60
50 60 70 80 90 100
pF1KE0 NRWALWFFKNDKSKTWQANLRLISKFDTVEDFWALYNHIQLSSNLMPGCDYSLFKDGIEP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NRWALWFFKNDKSKTWQANLRLISKFDTVEDFWALYNHIQLSSNLMPGCDYSLFKDGIEP
70 80 90 100 110 120
110 120 130 140 150 160
pF1KE0 MWEDEKNKRGGRWLITLNKQQRRSDLDRFWLETLLCLIGESFDDYSDDVCGAVVNVRAKG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MWEDEKNKRGGRWLITLNKQQRRSDLDRFWLETLLCLIGESFDDYSDDVCGAVVNVRAKG
130 140 150 160 170 180
170 180 190 200 210
pF1KE0 DKIAIWTTECENREAVTHIGRVYKERLGLPPKIVIGYQSHADTATKSGSTTKNRFVV
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DKIAIWTTECENREAVTHIGRVYKERLGLPPKIVIGYQSHADTATKSGSTTKNRFVV
190 200 210 220 230
>>NP_001317946 (OMIM: 133440,615091) eukaryotic translat (245 aa)
initn: 1460 init1: 1460 opt: 1460 Z-score: 1906.0 bits: 360.0 E(85289): 2e-99
Smith-Waterman score: 1460; 100.0% identity (100.0% similar) in 211 aa overlap (7-217:35-245)
10 20 30
pF1KE0 MATVEPETTPTPNPPTTEEEKTESNQEVANPEHYIK
::::::::::::::::::::::::::::::
NP_001 QNKKERKKMRAEDGENDAIKKQAESLRESQETTPTPNPPTTEEEKTESNQEVANPEHYIK
10 20 30 40 50 60
40 50 60 70 80 90
pF1KE0 HPLQNRWALWFFKNDKSKTWQANLRLISKFDTVEDFWALYNHIQLSSNLMPGCDYSLFKD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HPLQNRWALWFFKNDKSKTWQANLRLISKFDTVEDFWALYNHIQLSSNLMPGCDYSLFKD
70 80 90 100 110 120
100 110 120 130 140 150
pF1KE0 GIEPMWEDEKNKRGGRWLITLNKQQRRSDLDRFWLETLLCLIGESFDDYSDDVCGAVVNV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GIEPMWEDEKNKRGGRWLITLNKQQRRSDLDRFWLETLLCLIGESFDDYSDDVCGAVVNV
130 140 150 160 170 180
160 170 180 190 200 210
pF1KE0 RAKGDKIAIWTTECENREAVTHIGRVYKERLGLPPKIVIGYQSHADTATKSGSTTKNRFV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RAKGDKIAIWTTECENREAVTHIGRVYKERLGLPPKIVIGYQSHADTATKSGSTTKNRFV
190 200 210 220 230 240
pF1KE0 V
:
NP_001 V
>>NP_001124151 (OMIM: 133440,615091) eukaryotic translat (248 aa)
initn: 1484 init1: 941 opt: 941 Z-score: 1229.2 bits: 234.7 E(85289): 9.9e-62
Smith-Waterman score: 1426; 87.5% identity (87.5% similar) in 248 aa overlap (1-217:1-248)
10 20 30 40 50 60
pF1KE0 MATVEPETTPTPNPPTTEEEKTESNQEVANPEHYIKHPLQNRWALWFFKNDKSKTWQANL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MATVEPETTPTPNPPTTEEEKTESNQEVANPEHYIKHPLQNRWALWFFKNDKSKTWQANL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 RLISKFDTVEDFWALYNHIQLSSNLMPGCDYSLFKDGIEPMWEDEKNKRGGRWLITLNKQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RLISKFDTVEDFWALYNHIQLSSNLMPGCDYSLFKDGIEPMWEDEKNKRGGRWLITLNKQ
70 80 90 100 110 120
130 140
pF1KE0 QRRSDLDRFWLET-------------------------------LLCLIGESFDDYSDDV
::::::::::::: ::::::::::::::::
NP_001 QRRSDLDRFWLETRWDLAMLPRLVSNFWPQVILPLQPPKVLELQLLCLIGESFDDYSDDV
130 140 150 160 170 180
150 160 170 180 190 200
pF1KE0 CGAVVNVRAKGDKIAIWTTECENREAVTHIGRVYKERLGLPPKIVIGYQSHADTATKSGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CGAVVNVRAKGDKIAIWTTECENREAVTHIGRVYKERLGLPPKIVIGYQSHADTATKSGS
190 200 210 220 230 240
210
pF1KE0 TTKNRFVV
::::::::
NP_001 TTKNRFVV
>>NP_001263265 (OMIM: 605895) eukaryotic translation ini (234 aa)
initn: 368 init1: 203 opt: 440 Z-score: 576.4 bits: 113.9 E(85289): 2.3e-25
Smith-Waterman score: 442; 33.8% identity (67.6% similar) in 207 aa overlap (18-213:29-229)
10 20 30 40
pF1KE0 MATVEPETTPTPNPPTTEEEKTE--SNQEVANPEHYI----KHPLQNRW
:.:::: .:: .. . . .:::: .
NP_001 MNNKFDALKDDDSGDHDQNEENSTQKDGEKEKTERDKNQSSSKRKAVVPGPAEHPLQYNY
10 20 30 40 50 60
50 60 70 80 90
pF1KE0 ALWFFKND-----KSKTWQANLRLISKFDTVEDFWALYNHIQLSSNLMPGCDYSLFKDGI
..:. . .:.... :.. :. : .::.:: .:.:. ..: :. :::.::
NP_001 TFWYSRRTPGRPTSSQSYEQNIKQIGTFASVEQFWRFYSHMVRPGDLTGHSDFHLFKEGI
70 80 90 100 110 120
100 110 120 130 140 150
pF1KE0 EPMWEDEKNKRGGRWLITLNKQQRRSDLDRFWLETLLCLIGESFDDYSDDVCGAVVNVRA
.:::::. :: ::.:.: : :.. .: : . .: ..::.: ....:::::.::
NP_001 KPMWEDDANKNGGKWIIRL----RKGLASRCWENLILAMLGEQFM-VGEEICGAVVSVRF
130 140 150 160 170
160 170 180 190 200 210
pF1KE0 KGDKIAIWTTECENREAVTHIGRVYKERLGLPPKIVIGYQSHADTATKSGSTTKNRFVV
. : :.::. .. ....: . .. :.:::. .. :..:.:. :..:. .:
NP_001 QEDIISIWNKTASDQATTARIRDTLRRVLNLPPNTIMEYKTHTDSI-KDNSSFRNTKITL
180 190 200 210 220 230
>>NP_001317131 (OMIM: 605895) eukaryotic translation ini (240 aa)
initn: 364 init1: 203 opt: 439 Z-score: 574.9 bits: 113.6 E(85289): 2.8e-25
Smith-Waterman score: 441; 32.9% identity (65.7% similar) in 210 aa overlap (18-216:24-228)
10 20 30 40
pF1KE0 MATVEPETTPTPNPPTTEEEKTE--SNQEVANPEHYI----KHPLQNRWALWFF
:.:::: .:: .. . . .:::: ...:.
NP_001 MSLKDDDSGDHDQNEENSTQKDGEKEKTERDKNQSSSKRKAVVPGPAEHPLQYNYTFWYS
10 20 30 40 50 60
50 60 70 80 90 100
pF1KE0 KND-----KSKTWQANLRLISKFDTVEDFWALYNHIQLSSNLMPGCDYSLFKDGIEPMWE
. .:.... :.. :. : .::.:: .:.:. ..: :. :::.::.::::
NP_001 RRTPGRPTSSQSYEQNIKQIGTFASVEQFWRFYSHMVRPGDLTGHSDFHLFKEGIKPMWE
70 80 90 100 110 120
110 120 130 140 150 160
pF1KE0 DEKNKRGGRWLITLNKQQRRSDLDRFWLETLLCLIGESFDDYSDDVCGAVVNVRAKGDKI
:. :: ::.:.: : :.. .: : . .: ..::.: ....:::::.:: . : :
NP_001 DDANKNGGKWIIRL----RKGLASRCWENLILAMLGEQFM-VGEEICGAVVSVRFQEDII
130 140 150 160 170
170 180 190 200 210
pF1KE0 AIWTTECENREAVTHIGRVYKERLGLPPKIVIGYQSHADTATKSGSTTKNRFVV
.::. .. ....: . .. :.:::. .. :..:.:. : .:..
NP_001 SIWNKTASDQATTARIRDTLRRVLNLPPNTIMEYKTHTDSIKMPGRLGPQRLLFQNLWKP
180 190 200 210 220 230
NP_001 RLNVP
240
>>NP_004837 (OMIM: 605895) eukaryotic translation initia (245 aa)
initn: 364 init1: 203 opt: 439 Z-score: 574.7 bits: 113.6 E(85289): 2.8e-25
Smith-Waterman score: 441; 32.9% identity (65.7% similar) in 210 aa overlap (18-216:29-233)
10 20 30 40
pF1KE0 MATVEPETTPTPNPPTTEEEKTE--SNQEVANPEHYI----KHPLQNRW
:.:::: .:: .. . . .:::: .
NP_004 MNNKFDALKDDDSGDHDQNEENSTQKDGEKEKTERDKNQSSSKRKAVVPGPAEHPLQYNY
10 20 30 40 50 60
50 60 70 80 90
pF1KE0 ALWFFKND-----KSKTWQANLRLISKFDTVEDFWALYNHIQLSSNLMPGCDYSLFKDGI
..:. . .:.... :.. :. : .::.:: .:.:. ..: :. :::.::
NP_004 TFWYSRRTPGRPTSSQSYEQNIKQIGTFASVEQFWRFYSHMVRPGDLTGHSDFHLFKEGI
70 80 90 100 110 120
100 110 120 130 140 150
pF1KE0 EPMWEDEKNKRGGRWLITLNKQQRRSDLDRFWLETLLCLIGESFDDYSDDVCGAVVNVRA
.:::::. :: ::.:.: : :.. .: : . .: ..::.: ....:::::.::
NP_004 KPMWEDDANKNGGKWIIRL----RKGLASRCWENLILAMLGEQFM-VGEEICGAVVSVRF
130 140 150 160 170
160 170 180 190 200 210
pF1KE0 KGDKIAIWTTECENREAVTHIGRVYKERLGLPPKIVIGYQSHADTATKSGSTTKNRFVV
. : :.::. .. ....: . .. :.:::. .. :..:.:. : .:..
NP_004 QEDIISIWNKTASDQATTARIRDTLRRVLNLPPNTIMEYKTHTDSIKMPGRLGPQRLLFQ
180 190 200 210 220 230
NP_004 NLWKPRLNVP
240
>>NP_001269887 (OMIM: 605895) eukaryotic translation ini (236 aa)
initn: 364 init1: 203 opt: 432 Z-score: 565.9 bits: 111.9 E(85289): 8.8e-25
Smith-Waterman score: 434; 34.0% identity (67.5% similar) in 197 aa overlap (18-203:29-220)
10 20 30 40
pF1KE0 MATVEPETTPTPNPPTTEEEKTE--SNQEVANPEHYI----KHPLQNRW
:.:::: .:: .. . . .:::: .
NP_001 MNNKFDALKDDDSGDHDQNEENSTQKDGEKEKTERDKNQSSSKRKAVVPGPAEHPLQYNY
10 20 30 40 50 60
50 60 70 80 90
pF1KE0 ALWFFKND-----KSKTWQANLRLISKFDTVEDFWALYNHIQLSSNLMPGCDYSLFKDGI
..:. . .:.... :.. :. : .::.:: .:.:. ..: :. :::.::
NP_001 TFWYSRRTPGRPTSSQSYEQNIKQIGTFASVEQFWRFYSHMVRPGDLTGHSDFHLFKEGI
70 80 90 100 110 120
100 110 120 130 140 150
pF1KE0 EPMWEDEKNKRGGRWLITLNKQQRRSDLDRFWLETLLCLIGESFDDYSDDVCGAVVNVRA
.:::::. :: ::.:.: : :.. .: : . .: ..::.: ....:::::.::
NP_001 KPMWEDDANKNGGKWIIRL----RKGLASRCWENLILAMLGEQFM-VGEEICGAVVSVRF
130 140 150 160 170
160 170 180 190 200 210
pF1KE0 KGDKIAIWTTECENREAVTHIGRVYKERLGLPPKIVIGYQSHADTATKSGSTTKNRFVV
. : :.::. .. ....: . .. :.:::. .. :..:.:.
NP_001 QEDIISIWNKTASDQATTARIRDTLRRVLNLPPNTIMEYKTHTDSIKAWEEFHGLVNSSG
180 190 200 210 220 230
NP_001 R
>>NP_001263266 (OMIM: 605895) eukaryotic translation ini (189 aa)
initn: 370 init1: 203 opt: 370 Z-score: 486.6 bits: 96.9 E(85289): 2.3e-20
Smith-Waterman score: 370; 36.2% identity (68.7% similar) in 163 aa overlap (51-213:29-184)
30 40 50 60 70 80
pF1KE0 KTESNQEVANPEHYIKHPLQNRWALWFFKNDKSKTWQANLRLISKFDTVEDFWALYNHIQ
.: :: . . . :: ::.:: .:.:.
NP_001 MNNKFDALKDDDSGDHDQNEENSTQKDGEKEKTERDKNQSSSK-RKVEQFWRFYSHMV
10 20 30 40 50
90 100 110 120 130 140
pF1KE0 LSSNLMPGCDYSLFKDGIEPMWEDEKNKRGGRWLITLNKQQRRSDLDRFWLETLLCLIGE
..: :. :::.::.:::::. :: ::.:.: : :.. .: : . .: ..::
NP_001 RPGDLTGHSDFHLFKEGIKPMWEDDANKNGGKWIIRL----RKGLASRCWENLILAMLGE
60 70 80 90 100 110
150 160 170 180 190 200
pF1KE0 SFDDYSDDVCGAVVNVRAKGDKIAIWTTECENREAVTHIGRVYKERLGLPPKIVIGYQSH
.: ....:::::.:: . : :.::. .. ....: . .. :.:::. .. :..:
NP_001 QFM-VGEEICGAVVSVRFQEDIISIWNKTASDQATTARIRDTLRRVLNLPPNTIMEYKTH
120 130 140 150 160 170
210
pF1KE0 ADTATKSGSTTKNRFVV
.:. :..:. .:
NP_001 TDSI-KDNSSFRNTKITL
180
>>NP_001317130 (OMIM: 605895) eukaryotic translation ini (200 aa)
initn: 348 init1: 203 opt: 369 Z-score: 484.9 bits: 96.7 E(85289): 2.9e-20
Smith-Waterman score: 369; 34.9% identity (66.3% similar) in 166 aa overlap (51-216:29-188)
30 40 50 60 70 80
pF1KE0 KTESNQEVANPEHYIKHPLQNRWALWFFKNDKSKTWQANLRLISKFDTVEDFWALYNHIQ
.: :: . . . :: ::.:: .:.:.
NP_001 MNNKFDALKDDDSGDHDQNEENSTQKDGEKEKTERDKNQSSSK-RKVEQFWRFYSHMV
10 20 30 40 50
90 100 110 120 130 140
pF1KE0 LSSNLMPGCDYSLFKDGIEPMWEDEKNKRGGRWLITLNKQQRRSDLDRFWLETLLCLIGE
..: :. :::.::.:::::. :: ::.:.: : :.. .: : . .: ..::
NP_001 RPGDLTGHSDFHLFKEGIKPMWEDDANKNGGKWIIRL----RKGLASRCWENLILAMLGE
60 70 80 90 100 110
150 160 170 180 190 200
pF1KE0 SFDDYSDDVCGAVVNVRAKGDKIAIWTTECENREAVTHIGRVYKERLGLPPKIVIGYQSH
.: ....:::::.:: . : :.::. .. ....: . .. :.:::. .. :..:
NP_001 QFM-VGEEICGAVVSVRFQEDIISIWNKTASDQATTARIRDTLRRVLNLPPNTIMEYKTH
120 130 140 150 160 170
210
pF1KE0 ADTATKSGSTTKNRFVV
.:. : .:..
NP_001 TDSIKMPGRLGPQRLLFQNLWKPRLNVP
180 190 200
217 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sat Nov 5 04:26:18 2016 done: Sat Nov 5 04:26:19 2016
Total Scan time: 6.270 Total Display time: -0.010
Function used was FASTA [36.3.4 Apr, 2011]