Result of FASTA (omim) for
pFN21AB7668
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB7668, 402 aa
1>>>pF1KB7668 402 - 402 aa - 402 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 8.7848+/-0.000445; mu= 5.9278+/- 0.028
mean_var=393.9766+/-78.495, 0's: 0 Z-trim(122.7): 295 B-trim: 26 in 1/55
Lambda= 0.064616
statistics sampled from 40847 (41212) to 40847 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.795), E-opt: 0.2 (0.483), width: 16
Scan time: 10.060
The best scores are: opt bits E(85289)
NP_071758 (OMIM: 605992) LIM/homeobox protein Lhx5 ( 402) 2808 275.5 1.6e-73
NP_005559 (OMIM: 601999) LIM/homeobox protein Lhx1 ( 406) 2122 211.5 2.9e-54
NP_203129 (OMIM: 262700,602146) LIM/homeobox prote ( 390) 608 70.4 8.7e-12
XP_016870657 (OMIM: 221750,600577) PREDICTED: LIM/ ( 373) 556 65.5 2.4e-10
XP_005263467 (OMIM: 221750,600577) PREDICTED: LIM/ ( 386) 556 65.5 2.5e-10
NP_835258 (OMIM: 221750,600577) LIM/homeobox prote ( 397) 556 65.5 2.5e-10
NP_055379 (OMIM: 221750,600577) LIM/homeobox prote ( 402) 556 65.6 2.5e-10
NP_001167618 (OMIM: 161200,602575) LIM homeobox tr ( 402) 484 58.8 2.7e-08
NP_002307 (OMIM: 161200,602575) LIM homeobox trans ( 395) 481 58.5 3.2e-08
NP_001167617 (OMIM: 161200,602575) LIM homeobox tr ( 406) 475 58.0 4.8e-08
XP_011507842 (OMIM: 600298) PREDICTED: LIM homeobo ( 279) 468 57.1 6.1e-08
NP_001167540 (OMIM: 600298) LIM homeobox transcrip ( 382) 469 57.4 6.8e-08
NP_796372 (OMIM: 600298) LIM homeobox transcriptio ( 382) 469 57.4 6.8e-08
XP_016877994 (OMIM: 609481) PREDICTED: insulin gen ( 534) 453 56.1 2.3e-07
XP_011508408 (OMIM: 262700,602146) PREDICTED: LIM/ ( 329) 444 55.0 3.2e-07
XP_011508407 (OMIM: 262700,602146) PREDICTED: LIM/ ( 329) 444 55.0 3.2e-07
XP_006717386 (OMIM: 603759) PREDICTED: LIM/homeobo ( 314) 442 54.8 3.5e-07
NP_004780 (OMIM: 603759) LIM/homeobox protein Lhx2 ( 406) 442 54.9 4.1e-07
NP_001229263 (OMIM: 608215) LIM/homeobox protein L ( 363) 437 54.4 5.3e-07
NP_001229262 (OMIM: 608215) LIM/homeobox protein L ( 366) 437 54.4 5.3e-07
NP_954629 (OMIM: 608215) LIM/homeobox protein Lhx6 ( 377) 437 54.4 5.4e-07
XP_011516824 (OMIM: 608215) PREDICTED: LIM/homeobo ( 378) 437 54.4 5.4e-07
NP_055183 (OMIM: 608215) LIM/homeobox protein Lhx6 ( 392) 437 54.4 5.5e-07
XP_011516823 (OMIM: 608215) PREDICTED: LIM/homeobo ( 407) 437 54.5 5.6e-07
XP_005245407 (OMIM: 606066) PREDICTED: LIM/homeobo ( 336) 426 53.3 1e-06
XP_005251973 (OMIM: 608215) PREDICTED: LIM/homeobo ( 230) 422 52.7 1.1e-06
XP_016857338 (OMIM: 606066) PREDICTED: LIM/homeobo ( 378) 426 53.4 1.1e-06
NP_001014434 (OMIM: 606066) LIM/homeobox protein L ( 388) 426 53.4 1.1e-06
NP_064589 (OMIM: 606066) LIM/homeobox protein Lhx9 ( 397) 426 53.4 1.1e-06
XP_011508083 (OMIM: 606066) PREDICTED: LIM/homeobo ( 403) 426 53.4 1.1e-06
NP_002193 (OMIM: 600366) insulin gene enhancer pro ( 349) 420 52.8 1.5e-06
NP_001243043 (OMIM: 604425) LIM/homeobox protein L ( 346) 412 52.0 2.6e-06
NP_001001933 (OMIM: 604425) LIM/homeobox protein L ( 356) 412 52.1 2.6e-06
XP_016856805 (OMIM: 604425) PREDICTED: LIM/homeobo ( 363) 412 52.1 2.6e-06
XP_016856806 (OMIM: 604425) PREDICTED: LIM/homeobo ( 363) 412 52.1 2.6e-06
NP_665804 (OMIM: 609481) insulin gene enhancer pro ( 359) 409 51.8 3.2e-06
NP_006760 (OMIM: 603129) LIM domain transcription ( 165) 388 49.3 8e-06
XP_005271348 (OMIM: 603129) PREDICTED: LIM domain ( 165) 388 49.3 8e-06
XP_011518400 (OMIM: 186921) PREDICTED: rhombotin-1 ( 145) 365 47.1 3.3e-05
XP_011518401 (OMIM: 186921) PREDICTED: rhombotin-1 ( 145) 365 47.1 3.3e-05
NP_001257357 (OMIM: 186921) rhombotin-1 isoform b ( 155) 365 47.2 3.4e-05
NP_002306 (OMIM: 186921) rhombotin-1 isoform a [Ho ( 156) 365 47.2 3.4e-05
XP_006718291 (OMIM: 186921) PREDICTED: rhombotin-1 ( 193) 365 47.3 3.8e-05
XP_006719174 (OMIM: 180386) PREDICTED: LIM domain ( 145) 360 46.6 4.5e-05
XP_006719173 (OMIM: 180386) PREDICTED: LIM domain ( 145) 360 46.6 4.5e-05
XP_011519065 (OMIM: 180386) PREDICTED: LIM domain ( 145) 360 46.6 4.5e-05
NP_001001395 (OMIM: 180386) LIM domain only protei ( 145) 360 46.6 4.5e-05
XP_011519064 (OMIM: 180386) PREDICTED: LIM domain ( 145) 360 46.6 4.5e-05
NP_001230538 (OMIM: 180386) LIM domain only protei ( 145) 360 46.6 4.5e-05
NP_061110 (OMIM: 180386) LIM domain only protein 3 ( 145) 360 46.6 4.5e-05
>>NP_071758 (OMIM: 605992) LIM/homeobox protein Lhx5 [Ho (402 aa)
initn: 2808 init1: 2808 opt: 2808 Z-score: 1440.8 bits: 275.5 E(85289): 1.6e-73
Smith-Waterman score: 2808; 100.0% identity (100.0% similar) in 402 aa overlap (1-402:1-402)
10 20 30 40 50 60
pF1KB7 MMVHCAGCERPILDRFLLNVLDRAWHIKCVQCCECKTNLSEKCFSREGKLYCKNDFFRRF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_071 MMVHCAGCERPILDRFLLNVLDRAWHIKCVQCCECKTNLSEKCFSREGKLYCKNDFFRRF
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB7 GTKCAGCAQGISPSDLVRKARSKVFHLNCFTCMVCNKQLSTGEELYVIDENKFVCKDDYL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_071 GTKCAGCAQGISPSDLVRKARSKVFHLNCFTCMVCNKQLSTGEELYVIDENKFVCKDDYL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB7 SSSSLKEGSLNSVSSCTDRSLSPDLQDALQDDPKETDNSTSSDKETANNENEEQNSGTKR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_071 SSSSLKEGSLNSVSSCTDRSLSPDLQDALQDDPKETDNSTSSDKETANNENEEQNSGTKR
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB7 RGPRTTIKAKQLETLKAAFAATPKPTRHIREQLAQETGLNMRVIQVWFQNRRSKERRMKQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_071 RGPRTTIKAKQLETLKAAFAATPKPTRHIREQLAQETGLNMRVIQVWFQNRRSKERRMKQ
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB7 LSALGARRHAFFRSPRRMRPLGGRLDESEMLGSTPYTYYGDYQGDYYAPGSNYDFFAHGP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_071 LSALGARRHAFFRSPRRMRPLGGRLDESEMLGSTPYTYYGDYQGDYYAPGSNYDFFAHGP
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB7 PSQAQSPADSSFLAASGPGSTPLGALEPPLAGPHAADNPRFTDMISHPDTPSPEPGLPGT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_071 PSQAQSPADSSFLAASGPGSTPLGALEPPLAGPHAADNPRFTDMISHPDTPSPEPGLPGT
310 320 330 340 350 360
370 380 390 400
pF1KB7 LHPMPGEVFSGGPSPPFPMSGTSGYSGPLSHPNPELNEAAVW
::::::::::::::::::::::::::::::::::::::::::
NP_071 LHPMPGEVFSGGPSPPFPMSGTSGYSGPLSHPNPELNEAAVW
370 380 390 400
>>NP_005559 (OMIM: 601999) LIM/homeobox protein Lhx1 [Ho (406 aa)
initn: 1209 init1: 916 opt: 2122 Z-score: 1095.2 bits: 211.5 E(85289): 2.9e-54
Smith-Waterman score: 2122; 74.6% identity (90.0% similar) in 409 aa overlap (2-402:1-406)
10 20 30 40 50 60
pF1KB7 MMVHCAGCERPILDRFLLNVLDRAWHIKCVQCCECKTNLSEKCFSREGKLYCKNDFFRRF
:::::::.:::::::::::::::::.::::::::: ::.:::::::::::::::::: :
NP_005 MVHCAGCKRPILDRFLLNVLDRAWHVKCVQCCECKCNLTEKCFSREGKLYCKNDFFRCF
10 20 30 40 50
70 80 90 100 110 120
pF1KB7 GTKCAGCAQGISPSDLVRKARSKVFHLNCFTCMVCNKQLSTGEELYVIDENKFVCKDDYL
::::::::::::::::::.::::::::::::::.::::::::::::.:::::::::.:::
NP_005 GTKCAGCAQGISPSDLVRRARSKVFHLNCFTCMMCNKQLSTGEELYIIDENKFVCKEDYL
60 70 80 90 100 110
130 140 150 160 170
pF1KB7 SSSSL-KEGSLNSVSSCTDRSLSPDLQDALQDDPKETDNSTSSDKETANNENEEQNSGTK
:.::. ::.::.:... .: ::::: :: ::: :...... ::::...:::..:: :.:
NP_005 SNSSVAKENSLHSATTGSDPSLSPDSQDPSQDDAKDSESANVSDKEAGSNENDDQNLGAK
120 130 140 150 160 170
180 190 200 210 220 230
pF1KB7 RRGPRTTIKAKQLETLKAAFAATPKPTRHIREQLAQETGLNMRVIQVWFQNRRSKERRMK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 RRGPRTTIKAKQLETLKAAFAATPKPTRHIREQLAQETGLNMRVIQVWFQNRRSKERRMK
180 190 200 210 220 230
240 250 260 270 280 290
pF1KB7 QLSALGARRHAFFRSPRRMRPLGGRLDESEMLGSTPYTYYGDYQGDYYAPGSNYDFFAHG
:::::::::::::::::::::: ::. .:.. . :...:::::..::.::.::::: .:
NP_005 QLSALGARRHAFFRSPRRMRPLVDRLEPGELIPNGPFSFYGDYQSEYYGPGGNYDFFPQG
240 250 260 270 280 290
300 310 320 330 340 350
pF1KB7 PPS-QAQSPADSSFLAASGPGSTPLGALEPPLAGPH-AADNPRFTDMISHP--DTPSPEP
::: :::.:.: :. .:::..::::.:: :: : : ... ::::...:: :.:::::
NP_005 PPSSQAQTPVDLPFVPSSGPSGTPLGGLEHPLPGHHPSSEAQRFTDILAHPPGDSPSPEP
300 310 320 330 340 350
360 370 380 390 400
pF1KB7 GLPGTLHPMPGEVFSGGPSPPFP---MSGTSGYSGPLSHPNPELNEAAVW
.::: :: : .::: :::::: ..: ..:.. :::: ::.::::::
NP_005 SLPGPLHSMSAEVF--GPSPPFSSLSVNGGASYGNHLSHP-PEMNEAAVW
360 370 380 390 400
>>NP_203129 (OMIM: 262700,602146) LIM/homeobox protein L (390 aa)
initn: 891 init1: 565 opt: 608 Z-score: 332.6 bits: 70.4 E(85289): 8.7e-12
Smith-Waterman score: 836; 37.1% identity (61.0% similar) in 420 aa overlap (4-398:29-384)
10 20 30
pF1KB7 MMVHCAGCERPILDRFLLNVLDRAWHIKCVQCCEC
.::::.. :::.:.:.:::: :: .:..: .:
NP_203 MMQSATVPAEGAVKGLPEMLGVPMQQIPQCAGCNQHILDKFILKVLDRHWHSSCLKCADC
10 20 30 40 50 60
40 50 60 70 80 90
pF1KB7 KTNLSEKCFSREGKLYCKNDFFRRFGTKCAGCAQGISPSDLVRKARSKVFHLNCFTCMVC
. .:...:::: :..:::.:::.::::::..: ::: :...::::.. :.::.::.:..:
NP_203 QMQLADRCFSRAGSVYCKEDFFKRFGTKCTACQQGIPPTQVVRKAQDFVYHLHCFACIIC
70 80 90 100 110 120
100 110 120 130 140 150
pF1KB7 NKQLSTGEELYVIDENKFVCKDDYLSSSSLKEGSLNSVSSCTDRSLSPDLQDALQDDPKE
:.::.::.:.:.......:::.::
NP_203 NRQLATGDEFYLMEDGRLVCKEDY------------------------------------
130 140
160 170 180 190 200 210
pF1KB7 TDNSTSSDKETANNENEEQNSGTKRRGPRTTIKAKQLETLKAAFAATPKPTRHIREQLAQ
:::. .:.....:.:: ::::: :::::::: :. .:::.::.::::..
NP_203 ---------ETAK-QNDDSEAGAKR--PRTTITAKQLETLKNAYKNSPKPARHVREQLSS
150 160 170 180 190
220 230 240 250 260
pF1KB7 ETGLNMRVIQVWFQNRRSKERRMKQLSALGARRHAFFRSPRRMRPLGGR----------L
::::.:::.::::::::.::.:.:. .: : :..: .: : . . .
NP_203 ETGLDMRVVQVWFQNRRAKEKRLKK-DAGRHRWGQFYKSVKRSRGSSKQEKESSAEDCGV
200 210 220 230 240 250
270 280 290 300 310
pF1KB7 DESEM----------LGSTPYTY--YGDYQGDYYAPGSNYDFFAHGPPSQAQSPADSS-F
..::. :: : : :: : :: : : .. :. :.: .
NP_203 SDSELSFREDQILSELGHTNRIYGNVGDVTGGQLMNGS---FSMDGTGQSYQDLRDGSPY
260 270 280 290 300
320 330 340 350 360 370
pF1KB7 LAASGPGS-TPLGALEPPLAG-PHAADNPRFTDMISHPDTPSPEPGLPGTLHPMPGEVFS
..:.: . : . : : : ...:. .:.: :. ::. : .
NP_203 GIPQSPSSISSLPSHAPLLNGLDYTVDSN--LGIIAHAG-----QGVSQTLRAM-----A
310 320 330 340 350
380 390 400
pF1KB7 GGPSPPFPMSGTSGYSGPLSHPNPELNEAAVW
:::. . ... :: . :. :.:
NP_203 GGPTSDISTGSSVGYPDFPTSPGSWLDEMDHPPF
360 370 380 390
>>XP_016870657 (OMIM: 221750,600577) PREDICTED: LIM/home (373 aa)
initn: 934 init1: 549 opt: 556 Z-score: 306.6 bits: 65.5 E(85289): 2.4e-10
Smith-Waterman score: 862; 38.7% identity (61.3% similar) in 419 aa overlap (5-398:7-367)
10 20 30 40 50
pF1KB7 MMVHCAGCERPILDRFLLNVLDRAWHIKCVQCCECKTNLSEKCFSREGKLYCKNDFFR
::::.. :::::.:..::: :: ::..: .:.: :.:.:::: ..:::.:::.
XP_016 MQQIPLCAGCDQHILDRFILKALDRHWHSKCLKCSDCHTPLAERCFSRGESVYCKDDFFK
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB7 RFGTKCAGCAQGISPSDLVRKARSKVFHLNCFTCMVCNKQLSTGEELYVIDENKFVCKDD
:::::::.: :: :...::.:.. :.::.::.:.::..::.::.:.:.......::: :
XP_016 RFGTKCAACQLGIPPTQVVRRAQDFVYHLHCFACVVCKRQLATGDEFYLMEDSRLVCKAD
70 80 90 100 110 120
120 130 140 150 160 170
pF1KB7 YLSSSSLKEGSLNSVSSCTDRSLSPDLQDALQDDPKETDNSTSSDKETANNENEEQNSGT
: :::.... : .:
XP_016 Y---------------------------------------------ETAKQREAE---AT
130
180 190 200 210 220 230
pF1KB7 KRRGPRTTIKAKQLETLKAAFAATPKPTRHIREQLAQETGLNMRVIQVWFQNRRSKERRM
.: ::::: ::::::::.:. ..:::.::.::::..::::.:::.::::::::.::.:.
XP_016 AKR-PRTTITAKQLETLKSAYNTSPKPARHVREQLSSETGLDMRVVQVWFQNRRAKEKRL
140 150 160 170 180 190
240 250 260 270 280 290
pF1KB7 KQLSALGARRHAFFRSPRRMRPLGGRLDES---EMLGSTPYTYYGDYQGDYYAPGSNYDF
:. .: : .::. .: : :.. :.. : : . . : . .: .
XP_016 KK-DAGRQRWGQYFRNMKRSRG-GSKSDKDSVQEGQDSDAEVSFPDEPSLAEMGPANGLY
200 210 220 230 240
300 310 320 330 340
pF1KB7 FAHGPPSQA---QSPADSSFLAASG------------PGSTPLGALEPPLAGPHAADNPR
. : :.:: : : ..: : ::: : : . : :.:.. .:.
XP_016 GSLGEPTQALGRPSGALGNFSLEHGGLAGPEQYRELRPGS-PYG-VPPSPAAPQSLPGPQ
250 260 270 280 290 300
350 360 370 380 390
pF1KB7 -FTDMISHPDT-----PSPEPGLPGTLHPMPGEVFSG-GPSPPFPMSGTSGYSGPLSHPN
. . . .::: :: :: : : : .:..: ::: . ....:: . :
XP_016 PLLSSLVYPDTSLGLVPSGAPGGP----P-PMRVLAGNGPSSDLSTGSSGGYPDFPASPA
310 320 330 340 350 360
400
pF1KB7 PELNEAAVW
:.:
XP_016 SWLDEVDHAQF
370
>>XP_005263467 (OMIM: 221750,600577) PREDICTED: LIM/home (386 aa)
initn: 934 init1: 549 opt: 556 Z-score: 306.4 bits: 65.5 E(85289): 2.5e-10
Smith-Waterman score: 862; 38.7% identity (61.3% similar) in 419 aa overlap (5-398:20-380)
10 20 30 40
pF1KB7 MMVHCAGCERPILDRFLLNVLDRAWHIKCVQCCECKTNLSEKCFS
::::.. :::::.:..::: :: ::..: .:.: :.:.:::
XP_005 MTLNMKETRWGAPAPEIPLCAGCDQHILDRFILKALDRHWHSKCLKCSDCHTPLAERCFS
10 20 30 40 50 60
50 60 70 80 90 100
pF1KB7 REGKLYCKNDFFRRFGTKCAGCAQGISPSDLVRKARSKVFHLNCFTCMVCNKQLSTGEEL
: ..:::.:::.:::::::.: :: :...::.:.. :.::.::.:.::..::.::.:.
XP_005 RGESVYCKDDFFKRFGTKCAACQLGIPPTQVVRRAQDFVYHLHCFACVVCKRQLATGDEF
70 80 90 100 110 120
110 120 130 140 150 160
pF1KB7 YVIDENKFVCKDDYLSSSSLKEGSLNSVSSCTDRSLSPDLQDALQDDPKETDNSTSSDKE
:.......::: :: :
XP_005 YLMEDSRLVCKADY---------------------------------------------E
130
170 180 190 200 210 220
pF1KB7 TANNENEEQNSGTKRRGPRTTIKAKQLETLKAAFAATPKPTRHIREQLAQETGLNMRVIQ
::.... : .: .: ::::: ::::::::.:. ..:::.::.::::..::::.:::.:
XP_005 TAKQREAE---ATAKR-PRTTITAKQLETLKSAYNTSPKPARHVREQLSSETGLDMRVVQ
140 150 160 170 180 190
230 240 250 260 270 280
pF1KB7 VWFQNRRSKERRMKQLSALGARRHAFFRSPRRMRPLGGRLDES---EMLGSTPYTYYGDY
:::::::.::.:.:. .: : .::. .: : :.. :.. : : . . :
XP_005 VWFQNRRAKEKRLKK-DAGRQRWGQYFRNMKRSRG-GSKSDKDSVQEGQDSDAEVSFPDE
200 210 220 230 240
290 300 310 320
pF1KB7 QGDYYAPGSNYDFFAHGPPSQA---QSPADSSFLAASG------------PGSTPLGALE
. .: . . : :.:: : : ..: : ::: : : .
XP_005 PSLAEMGPANGLYGSLGEPTQALGRPSGALGNFSLEHGGLAGPEQYRELRPGS-PYG-VP
250 260 270 280 290 300
330 340 350 360 370 380
pF1KB7 PPLAGPHAADNPR-FTDMISHPDT-----PSPEPGLPGTLHPMPGEVFSG-GPSPPFPMS
: :.:.. .:. . . . .::: :: :: : : : .:..: ::: . .
XP_005 PSPAAPQSLPGPQPLLSSLVYPDTSLGLVPSGAPGGP----P-PMRVLAGNGPSSDLSTG
310 320 330 340 350 360
390 400
pF1KB7 GTSGYSGPLSHPNPELNEAAVW
...:: . : :.:
XP_005 SSGGYPDFPASPASWLDEVDHAQF
370 380
>>NP_835258 (OMIM: 221750,600577) LIM/homeobox protein L (397 aa)
initn: 934 init1: 549 opt: 556 Z-score: 306.3 bits: 65.5 E(85289): 2.5e-10
Smith-Waterman score: 862; 38.7% identity (61.3% similar) in 419 aa overlap (5-398:31-391)
10 20 30
pF1KB7 MMVHCAGCERPILDRFLLNVLDRAWHIKCVQCCE
::::.. :::::.:..::: :: ::..: .
NP_835 MLLETGLERDRARPGAAAVCTLGGTREIPLCAGCDQHILDRFILKALDRHWHSKCLKCSD
10 20 30 40 50 60
40 50 60 70 80 90
pF1KB7 CKTNLSEKCFSREGKLYCKNDFFRRFGTKCAGCAQGISPSDLVRKARSKVFHLNCFTCMV
:.: :.:.:::: ..:::.:::.:::::::.: :: :...::.:.. :.::.::.:.:
NP_835 CHTPLAERCFSRGESVYCKDDFFKRFGTKCAACQLGIPPTQVVRRAQDFVYHLHCFACVV
70 80 90 100 110 120
100 110 120 130 140 150
pF1KB7 CNKQLSTGEELYVIDENKFVCKDDYLSSSSLKEGSLNSVSSCTDRSLSPDLQDALQDDPK
:..::.::.:.:.......::: ::
NP_835 CKRQLATGDEFYLMEDSRLVCKADY-----------------------------------
130 140
160 170 180 190 200 210
pF1KB7 ETDNSTSSDKETANNENEEQNSGTKRRGPRTTIKAKQLETLKAAFAATPKPTRHIREQLA
:::.... : .: .: ::::: ::::::::.:. ..:::.::.::::.
NP_835 ----------ETAKQREAE---ATAKR-PRTTITAKQLETLKSAYNTSPKPARHVREQLS
150 160 170 180 190
220 230 240 250 260 270
pF1KB7 QETGLNMRVIQVWFQNRRSKERRMKQLSALGARRHAFFRSPRRMRPLGGRLDES---EML
.::::.:::.::::::::.::.:.:. .: : .::. .: : :.. :.. :
NP_835 SETGLDMRVVQVWFQNRRAKEKRLKK-DAGRQRWGQYFRNMKRSRG-GSKSDKDSVQEGQ
200 210 220 230 240
280 290 300 310
pF1KB7 GSTPYTYYGDYQGDYYAPGSNYDFFAHGPPSQA---QSPADSSFLAASG-----------
: . . : . .: . . : :.:: : : ..: :
NP_835 DSDAEVSFPDEPSLAEMGPANGLYGSLGEPTQALGRPSGALGNFSLEHGGLAGPEQYREL
250 260 270 280 290 300
320 330 340 350 360 370
pF1KB7 -PGSTPLGALEPPLAGPHAADNPR-FTDMISHPDT-----PSPEPGLPGTLHPMPGEVFS
::: : : . : :.:.. .:. . . . .::: :: :: : : : .:..
NP_835 RPGS-PYG-VPPSPAAPQSLPGPQPLLSSLVYPDTSLGLVPSGAPGGP----P-PMRVLA
310 320 330 340 350 360
380 390 400
pF1KB7 G-GPSPPFPMSGTSGYSGPLSHPNPELNEAAVW
: ::: . ....:: . : :.:
NP_835 GNGPSSDLSTGSSGGYPDFPASPASWLDEVDHAQF
370 380 390
>>NP_055379 (OMIM: 221750,600577) LIM/homeobox protein L (402 aa)
initn: 934 init1: 549 opt: 556 Z-score: 306.3 bits: 65.6 E(85289): 2.5e-10
Smith-Waterman score: 862; 38.7% identity (61.3% similar) in 419 aa overlap (5-398:36-396)
10 20 30
pF1KB7 MMVHCAGCERPILDRFLLNVLDRAWHIKCVQCCE
::::.. :::::.:..::: :: ::..: .
NP_055 ELGPARESAGGDLLLALLARRADLRREIPLCAGCDQHILDRFILKALDRHWHSKCLKCSD
10 20 30 40 50 60
40 50 60 70 80 90
pF1KB7 CKTNLSEKCFSREGKLYCKNDFFRRFGTKCAGCAQGISPSDLVRKARSKVFHLNCFTCMV
:.: :.:.:::: ..:::.:::.:::::::.: :: :...::.:.. :.::.::.:.:
NP_055 CHTPLAERCFSRGESVYCKDDFFKRFGTKCAACQLGIPPTQVVRRAQDFVYHLHCFACVV
70 80 90 100 110 120
100 110 120 130 140 150
pF1KB7 CNKQLSTGEELYVIDENKFVCKDDYLSSSSLKEGSLNSVSSCTDRSLSPDLQDALQDDPK
:..::.::.:.:.......::: ::
NP_055 CKRQLATGDEFYLMEDSRLVCKADY-----------------------------------
130 140 150
160 170 180 190 200 210
pF1KB7 ETDNSTSSDKETANNENEEQNSGTKRRGPRTTIKAKQLETLKAAFAATPKPTRHIREQLA
:::.... : .: .: ::::: ::::::::.:. ..:::.::.::::.
NP_055 ----------ETAKQREAE---ATAKR-PRTTITAKQLETLKSAYNTSPKPARHVREQLS
160 170 180 190
220 230 240 250 260 270
pF1KB7 QETGLNMRVIQVWFQNRRSKERRMKQLSALGARRHAFFRSPRRMRPLGGRLDES---EML
.::::.:::.::::::::.::.:.:. .: : .::. .: : :.. :.. :
NP_055 SETGLDMRVVQVWFQNRRAKEKRLKK-DAGRQRWGQYFRNMKRSRG-GSKSDKDSVQEGQ
200 210 220 230 240 250
280 290 300 310
pF1KB7 GSTPYTYYGDYQGDYYAPGSNYDFFAHGPPSQA---QSPADSSFLAASG-----------
: . . : . .: . . : :.:: : : ..: :
NP_055 DSDAEVSFPDEPSLAEMGPANGLYGSLGEPTQALGRPSGALGNFSLEHGGLAGPEQYREL
260 270 280 290 300 310
320 330 340 350 360 370
pF1KB7 -PGSTPLGALEPPLAGPHAADNPR-FTDMISHPDT-----PSPEPGLPGTLHPMPGEVFS
::: : : . : :.:.. .:. . . . .::: :: :: : : : .:..
NP_055 RPGS-PYG-VPPSPAAPQSLPGPQPLLSSLVYPDTSLGLVPSGAPGGP----P-PMRVLA
320 330 340 350 360
380 390 400
pF1KB7 G-GPSPPFPMSGTSGYSGPLSHPNPELNEAAVW
: ::: . ....:: . : :.:
NP_055 GNGPSSDLSTGSSGGYPDFPASPASWLDEVDHAQF
370 380 390 400
>>NP_001167618 (OMIM: 161200,602575) LIM homeobox transc (402 aa)
initn: 616 init1: 400 opt: 484 Z-score: 270.0 bits: 58.8 E(85289): 2.7e-08
Smith-Waterman score: 695; 37.4% identity (65.5% similar) in 313 aa overlap (5-309:56-345)
10 20 30
pF1KB7 MMVHCAGCERPILDRFLLNVLDRAWHIKCVQCCE
: ::.::: ::::. : . .:: .:.::
NP_001 DGIKMEEHALRPGPATLGVLLGSDCPHPAVCEGCQRPISDRFLMRVNESSWHEECLQCAA
30 40 50 60 70 80
40 50 60 70 80 90
pF1KB7 CKTNLSEKCFSREGKLYCKNDFFRRFGTKCAGCAQGISPSDLVRKARSKVFHLNCFTCMV
:. :. .:. :. :::::.:. . :..::.:: . :.:...: .: :.::.:: : :
NP_001 CQQALTTSCYFRDRKLYCKQDYQQLFAAKCSGCMEKIAPTEFVMRALECVYHLGCFCCCV
90 100 110 120 130 140
100 110 120 130 140 150
pF1KB7 CNKQLSTGEELYVIDENKFVCKDDYLSSSSLKEGSLNSVSSCTDRSLSPDLQDALQDDPK
:..:: :.: .:. :....:: :: :: .: : :.::: .:..... .
NP_001 CERQLRKGDE-FVLKEGQLLCKGDYE-----KEKDLLS-------SVSPDESDSVKSEDE
150 160 170 180 190
160 170 180 190 200 210
pF1KB7 ETDNSTSSDKETANNENEEQNSGTKR-RGPRTTIKAKQLETLKAAFAATPKPTRHIREQL
. : . .. . . .. . .... .: . ::: . ..: ...::.: .. :: :..:: :
NP_001 DGDMKPAKGQGSQSKGSGDDGKDPRRPKRPRTILTTQQRRAFKASFEVSSKPCRKVRETL
200 210 220 230 240 250
220 230 240 250 260 270
pF1KB7 AQETGLNMRVIQVWFQNRRSKERRMKQLSALGARRHAFFRSPRRMRPLGGRLDESEMLGS
: ::::..::.::::::.:.: ::.: :::: . . . :: .. :.: :
NP_001 AAETGLSVRVVQVWFQNQRAK---MKKL----ARRHQQQQEQQNSQRLGQEVLSSRMEGM
260 270 280 290 300
280 290 300 310 320
pF1KB7 -TPYTYYGDYQGDYYA----PGSNYDFFAHG--PPSQAQSPADSSFLAASGPGSTPLGAL
. :: . : . : : .. : : .: :: : :.:
NP_001 MASYTPLAPPQQQIVAMEQSPYGSSDPFQQGLTPP---QMPGDHMNPYGNDSIFHDIDSD
310 320 330 340 350 360
330 340 350 360 370 380
pF1KB7 EPPLAGPHAADNPRFTDMISHPDTPSPEPGLPGTLHPMPGEVFSGGPSPPFPMSGTSGYS
NP_001 TSLTSLSDCFLGSSDVGSLQARVGNPIDRLYSMQSSYFAS
370 380 390 400
>>NP_002307 (OMIM: 161200,602575) LIM homeobox transcrip (395 aa)
initn: 616 init1: 400 opt: 481 Z-score: 268.6 bits: 58.5 E(85289): 3.2e-08
Smith-Waterman score: 700; 35.3% identity (64.5% similar) in 346 aa overlap (5-333:56-381)
10 20 30
pF1KB7 MMVHCAGCERPILDRFLLNVLDRAWHIKCVQCCE
: ::.::: ::::. : . .:: .:.::
NP_002 DGIKMEEHALRPGPATLGVLLGSDCPHPAVCEGCQRPISDRFLMRVNESSWHEECLQCAA
30 40 50 60 70 80
40 50 60 70 80 90
pF1KB7 CKTNLSEKCFSREGKLYCKNDFFRRFGTKCAGCAQGISPSDLVRKARSKVFHLNCFTCMV
:. :. .:. :. :::::.:. . :..::.:: . :.:...: .: :.::.:: : :
NP_002 CQQALTTSCYFRDRKLYCKQDYQQLFAAKCSGCMEKIAPTEFVMRALECVYHLGCFCCCV
90 100 110 120 130 140
100 110 120 130 140 150
pF1KB7 CNKQLSTGEELYVIDENKFVCKDDYLSSSSLKEGSLNSVSSCTDRSLSPDLQDALQDDPK
:..:: :.: .:. :....:: :: :: .: : :.::: .:..... .
NP_002 CERQLRKGDE-FVLKEGQLLCKGDYE-----KEKDLLS-------SVSPDESDSVKSEDE
150 160 170 180 190
160 170 180 190 200 210
pF1KB7 ETDNSTSSDKETANNENEEQNSGTKR-RGPRTTIKAKQLETLKAAFAATPKPTRHIREQL
. : . .. . . .. . .... .: . ::: . ..: ...::.: .. :: :..:: :
NP_002 DGDMKPAKGQGSQSKGSGDDGKDPRRPKRPRTILTTQQRRAFKASFEVSSKPCRKVRETL
200 210 220 230 240 250
220 230 240 250 260 270
pF1KB7 AQETGLNMRVIQVWFQNRRSKERRMKQLSALGARRHAFFRSPRRMRPLGGRLDESEMLGS
: ::::..::.::::::.:.: ::.: :::: . . . :: .. :.: :
NP_002 AAETGLSVRVVQVWFQNQRAK---MKKL----ARRHQQQQEQQNSQRLGQEVLSSRMEGM
260 270 280 290 300
280 290 300 310
pF1KB7 -TPYTYYGDYQGDYYA----PGSNYDFFAHG--PPSQAQSPA-------DSSFLAASGP-
. :: . : . : : .. : : .: ::.. . . :.:. . :
NP_002 MASYTPLAPPQQQIVAMEQSPYGSSDPFQQGLTPPQMPGNDSIFHDIDSDTSLTSLSDCF
310 320 330 340 350 360
320 330 340 350 360 370
pF1KB7 -GSTPLGALEPPLAGPHAADNPRFTDMISHPDTPSPEPGLPGTLHPMPGEVFSGGPSPPF
::. .:.:. ...:
NP_002 LGSSDVGSLQARVGNPIDRLYSMQSSYFAS
370 380 390
>>NP_001167617 (OMIM: 161200,602575) LIM homeobox transc (406 aa)
initn: 616 init1: 400 opt: 475 Z-score: 265.4 bits: 58.0 E(85289): 4.8e-08
Smith-Waterman score: 680; 34.0% identity (63.1% similar) in 350 aa overlap (5-333:56-392)
10 20 30
pF1KB7 MMVHCAGCERPILDRFLLNVLDRAWHIKCVQCCE
: ::.::: ::::. : . .:: .:.::
NP_001 DGIKMEEHALRPGPATLGVLLGSDCPHPAVCEGCQRPISDRFLMRVNESSWHEECLQCAA
30 40 50 60 70 80
40 50 60 70 80 90
pF1KB7 CKTNLSEKCFSREGKLYCKNDFFRRFGTKCAGCAQGISPSDLVRKARSKVFHLNCFTCMV
:. :. .:. :. :::::.:. . :..::.:: . :.:...: .: :.::.:: : :
NP_001 CQQALTTSCYFRDRKLYCKQDYQQLFAAKCSGCMEKIAPTEFVMRALECVYHLGCFCCCV
90 100 110 120 130 140
100 110 120 130 140 150
pF1KB7 CNKQLSTGEELYVIDENKFVCKDDYLSSSSLKEGSLNSVSSCTDRSLSPDLQDALQDDPK
:..:: :.: .:. :....:: :: :: .: : :.::: .:..... .
NP_001 CERQLRKGDE-FVLKEGQLLCKGDYE-----KEKDLLS-------SVSPDESDSVKSEDE
150 160 170 180 190
160 170 180 190 200 210
pF1KB7 ETDNSTSSDKETANNENEEQNSGTKR-RGPRTTIKAKQLETLKAAFAATPKPTRHIREQL
. : . .. . . .. . .... .: . ::: . ..: ...::.: .. :: :..:: :
NP_001 DGDMKPAKGQGSQSKGSGDDGKDPRRPKRPRTILTTQQRRAFKASFEVSSKPCRKVRETL
200 210 220 230 240 250
220 230 240 250 260
pF1KB7 AQETGLNMRVIQVWFQNRRSK----ERRMKQLSALGARRHAFFRSPRRMRPLGGRLDESE
: ::::..::.::::::.:.: :: .: . .. : . :: .. :.
NP_001 AAETGLSVRVVQVWFQNQRAKMKKLARRHQQQQEQQNSQRLGQGEPGPGQGLGQEVLSSR
260 270 280 290 300 310
270 280 290 300 310
pF1KB7 MLGS-TPYTYYGDYQGDYYA----PGSNYDFFAHG--PPSQAQSPA-------DSSFLAA
: : . :: . : . : : .. : : .: ::.. . . :.:. .
NP_001 MEGMMASYTPLAPPQQQIVAMEQSPYGSSDPFQQGLTPPQMPGNDSIFHDIDSDTSLTSL
320 330 340 350 360 370
320 330 340 350 360 370
pF1KB7 SGP--GSTPLGALEPPLAGPHAADNPRFTDMISHPDTPSPEPGLPGTLHPMPGEVFSGGP
: ::. .:.:. ...:
NP_001 SDCFLGSSDVGSLQARVGNPIDRLYSMQSSYFAS
380 390 400
402 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sat Nov 5 04:05:35 2016 done: Sat Nov 5 04:05:36 2016
Total Scan time: 10.060 Total Display time: 0.020
Function used was FASTA [36.3.4 Apr, 2011]