Result of FASTA (ccds) for
pFN21AE0805
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE0805, 360 aa
1>>>pF1KE0805 360 - 360 aa - 360 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.4731+/-0.00105; mu= 16.0806+/- 0.063
mean_var=195.7431+/-83.683, 0's: 0 Z-trim(105.5): 315 B-trim: 913 in 2/49
Lambda= 0.091671
statistics sampled from 7947 (8461) to 7947 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.61), E-opt: 0.2 (0.26), width: 16
Scan time: 2.080
The best scores are: opt bits E(32554)
CCDS13449.2 MC3R gene_id:4159|Hs108|chr20 ( 323) 2166 299.8 2.2e-81
CCDS11868.1 MC5R gene_id:4161|Hs108|chr18 ( 325) 1325 188.5 6.7e-48
CCDS11976.1 MC4R gene_id:4160|Hs108|chr18 ( 332) 1273 181.7 8e-46
CCDS56011.1 MC1R gene_id:4157|Hs108|chr16 ( 317) 958 140.0 2.7e-33
CCDS11869.1 MC2R gene_id:4158|Hs108|chr18 ( 297) 583 90.3 2.2e-18
>>CCDS13449.2 MC3R gene_id:4159|Hs108|chr20 (323 aa)
initn: 2166 init1: 2166 opt: 2166 Z-score: 1574.6 bits: 299.8 E(32554): 2.2e-81
Smith-Waterman score: 2166; 100.0% identity (100.0% similar) in 323 aa overlap (38-360:1-323)
10 20 30 40 50 60
pF1KE0 LEGDFVFPVSSSSFLRTLLEPQLGSALLTAMNASCCLPSVQPTLPNGSEHLQAPFFSNQS
::::::::::::::::::::::::::::::
CCDS13 MNASCCLPSVQPTLPNGSEHLQAPFFSNQS
10 20 30
70 80 90 100 110 120
pF1KE0 SSAFCEQVFIKPEVFLSLGIVSLLENILVILAVVRNGNLHSPMYFFLCSLAVADMLVSVS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS13 SSAFCEQVFIKPEVFLSLGIVSLLENILVILAVVRNGNLHSPMYFFLCSLAVADMLVSVS
40 50 60 70 80 90
130 140 150 160 170 180
pF1KE0 NALETIMIAIVHSDYLTFEDQFIQHMDNIFDSMICISLVASICNLLAIAVDRYVTIFYAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS13 NALETIMIAIVHSDYLTFEDQFIQHMDNIFDSMICISLVASICNLLAIAVDRYVTIFYAL
100 110 120 130 140 150
190 200 210 220 230 240
pF1KE0 RYHSIMTVRKALTLIVAIWVCCGVCGVVFIVYSESKMVIVCLITMFFAMMLLMGTLYVHM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS13 RYHSIMTVRKALTLIVAIWVCCGVCGVVFIVYSESKMVIVCLITMFFAMMLLMGTLYVHM
160 170 180 190 200 210
250 260 270 280 290 300
pF1KE0 FLFARLHVKRIAALPPADGVAPQQHSCMKGAVTITILLGVFIFCWAPFFLHLVLIITCPT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS13 FLFARLHVKRIAALPPADGVAPQQHSCMKGAVTITILLGVFIFCWAPFFLHLVLIITCPT
220 230 240 250 260 270
310 320 330 340 350 360
pF1KE0 NPYCICYTAHFNTYLVLIMCNSVIDPLIYAFRSLELRNTFREILCGCNGMNLG
:::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS13 NPYCICYTAHFNTYLVLIMCNSVIDPLIYAFRSLELRNTFREILCGCNGMNLG
280 290 300 310 320
>>CCDS11868.1 MC5R gene_id:4161|Hs108|chr18 (325 aa)
initn: 1280 init1: 891 opt: 1325 Z-score: 973.4 bits: 188.5 E(32554): 6.7e-48
Smith-Waterman score: 1325; 61.6% identity (85.1% similar) in 323 aa overlap (38-359:1-317)
10 20 30 40 50 60
pF1KE0 LEGDFVFPVSSSSFLRTLLEPQLGSALLTAMNASCCLPSVQPTLPNGSE-HLQAPFFSNQ
::.: : .. .: :..: .:..: .:.
CCDS11 MNSSFHLHFLDLNL-NATEGNLSGPNVKNK
10 20
70 80 90 100 110 120
pF1KE0 SSSAFCEQVFIKPEVFLSLGIVSLLENILVILAVVRNGNLHSPMYFFLCSLAVADMLVSV
:: ::.. : ::::.::..::::::::: :.:.: :::::::::.:::::::::::.
CCDS11 SSP--CEDMGIAVEVFLTLGVISLLENILVIGAIVKNKNLHSPMYFFVCSLAVADMLVSM
30 40 50 60 70 80
130 140 150 160 170 180
pF1KE0 SNALETIMIAIVHSDYLTFEDQFIQHMDNIFDSMICISLVASICNLLAIAVDRYVTIFYA
:.: ::: : .... .:.. : :..:.::.::::::::.:::.:.:::::::::::::::
CCDS11 SSAWETITIYLLNNKHLVIADAFVRHIDNVFDSMICISVVASMCSLLAIAVDRYVTIFYA
90 100 110 120 130 140
190 200 210 220 230 240
pF1KE0 LRYHSIMTVRKALTLIVAIWVCCGVCGVVFIVYSESKMVIVCLITMFFAMMLLMGTLYVH
:::: :::.:.. ..:..::. : ::.:::.:::: .::.:::.:::::..:. .::.:
CCDS11 LRYHHIMTARRSGAIIAGIWAFCTGCGIVFILYSESTYVILCLISMFFAMLFLLVSLYIH
150 160 170 180 190 200
250 260 270 280 290 300
pF1KE0 MFLFARLHVKRIAALPPADGVAPQQHSCMKGAVTITILLGVFIFCWAPFFLHLVLIITCP
:::.:: ::::::::: :. . .:.. :.::::.:.::::: :::::::::.:...::
CCDS11 MFLLARTHVKRIAALPGAS--SARQRTSMQGAVTVTMLLGVFTVCWAPFFLHLTLMLSCP
210 220 230 240 250 260
310 320 330 340 350 360
pF1KE0 TNPYCICYTAHFNTYLVLIMCNSVIDPLIYAFRSLELRNTFREILCGCNGMNLG
: :: . .::: ::.:::::::.::::::::: :.:.::.::.: : :. .
CCDS11 QNLYCSRFMSHFNMYLILIMCNSVMDPLIYAFRSQEMRKTFKEIIC-CRGFRIACSFPRR
270 280 290 300 310 320
CCDS11 D
>>CCDS11976.1 MC4R gene_id:4160|Hs108|chr18 (332 aa)
initn: 1267 init1: 514 opt: 1273 Z-score: 936.2 bits: 181.7 E(32554): 8e-46
Smith-Waterman score: 1273; 61.4% identity (85.5% similar) in 303 aa overlap (53-354:26-319)
30 40 50 60 70 80
pF1KE0 RTLLEPQLGSALLTAMNASCCLPSVQPTLPNGSEHLQAPFFSNQSSSAFC-EQVFIKPEV
:.:: : . :.. : ::.:..:::
CCDS11 MVNSTHRGMHTSLHLWNRSSYRLHSNASESLGKGY-----SDGGCYEQLFVSPEV
10 20 30 40 50
90 100 110 120 130 140
pF1KE0 FLSLGIVSLLENILVILAVVRNGNLHSPMYFFLCSLAVADMLVSVSNALETIMIAIVHSD
:..::..:::::::::.:...: :::::::::.::::::::::::::. :::.:....:
CCDS11 FVTLGVISLLENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNST
60 70 80 90 100 110
150 160 170 180 190 200
pF1KE0 YLTFEDQFIQHMDNIFDSMICISLVASICNLLAIAVDRYVTIFYALRYHSIMTVRKALTL
: ..: ..::..::.:: ::.::::.::.:::::: ::::::.::.::::... .
CCDS11 D-TDAQSFTVNIDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGII
120 130 140 150 160
210 220 230 240 250 260
pF1KE0 IVAIWVCCGVCGVVFIVYSESKMVIVCLITMFFAMMLLMGTLYVHMFLFARLHVKRIAAL
: ::. : : :..::.::.:. ::.:::::::.:. ::..:::::::.::::.::::.:
CCDS11 ISCIWAACTVSGILFIIYSDSSAVIICLITMFFTMLALMASLYVHMFLMARLHIKRIAVL
170 180 190 200 210 220
270 280 290 300 310 320
pF1KE0 PPADGVAPQQHSCMKGAVTITILLGVFIFCWAPFFLHLVLIITCPTNPYCICYTAHFNTY
: . .. .: . ::::.:.:::.:::. :::::::::.. :.:: ::::.:. .::: :
CCDS11 PGTGAI--RQGANMKGAITLTILIGVFVVCWAPFFLHLIFYISCPQNPYCVCFMSHFNLY
230 240 250 260 270 280
330 340 350 360
pF1KE0 LVLIMCNSVIDPLIYAFRSLELRNTFREILCGCNGMNLG
:.::::::.:::::::.:: :::.::.::.: :
CCDS11 LILIMCNSIIDPLIYALRSQELRKTFKEIIC-CYPLGGLCDLSSRY
290 300 310 320 330
>>CCDS56011.1 MC1R gene_id:4157|Hs108|chr16 (317 aa)
initn: 940 init1: 584 opt: 958 Z-score: 711.2 bits: 140.0 E(32554): 2.7e-33
Smith-Waterman score: 958; 49.5% identity (77.6% similar) in 295 aa overlap (59-352:23-315)
30 40 50 60 70 80
pF1KE0 QLGSALLTAMNASCCLPSVQPTLPNGSEHLQAPFFSNQSSSAFCEQVFIKPEVFLSLGIV
: . .::.. : : .: :. .:::::.:
CCDS56 MAVQGSQRRLLGSLNSTPTAIPQLGLAANQTG-ARCLEVSISDGLFLSLGLV
10 20 30 40 50
90 100 110 120 130 140
pF1KE0 SLLENILVILAVVRNGNLHSPMYFFLCSLAVADMLVSVSNALETIMIAIVHSDYLTFEDQ
::.:: ::. ....: ::::::: :.: ::..:.::: ::.::: .: .... :. .
CCDS56 SLVENALVVATIAKNRNLHSPMYCFICCLALSDLLVSGSNVLETAVILLLEAGALVARAA
60 70 80 90 100 110
150 160 170 180 190 200
pF1KE0 FIQHMDNIFDSMICISLVASICNLLAIAVDRYVTIFYALRYHSIMTVRKALTLIVAIWVC
.:..::..: . : :...:.: : :::::::..::::::::::.:. .: ..::::
CCDS56 VLQQLDNVIDVITCSSMLSSLCFLGAIAVDRYISIFYALRYHSIVTLPRARRAVAAIWVA
120 130 140 150 160 170
210 220 230 240 250 260
pF1KE0 CGVCGVVFIVYSESKMVIVCLITMFFAMMLLMGTLYVHMFLFARLHVKRIAALPPADGVA
: ...::.: . :..::...:.::..::..:::::. : :.. :: : . .
CCDS56 SVVFSTLFIAYYDHVAVLLCLVVFFLAMLVLMAVLYVHMLARACQHAQGIARLHKRQRPV
180 190 200 210 220 230
270 280 290 300 310 320
pF1KE0 PQQHSCMKGAVTITILLGVFIFCWAPFFLHLVLIITCPTNPYCICYTAHFNTYLVLIMCN
: . .:::::.:::::.:..::.::::::.::. :: .: : : .:: .:.::.::
CCDS56 HQGFG-LKGAVTLTILLGIFFLCWGPFFLHLTLIVLCPEHPTCGCIFKNFNLFLALIICN
240 250 260 270 280 290
330 340 350 360
pF1KE0 SVIDPLIYAFRSLELRNTFREIL-CGCNGMNLG
..::::::::.: ::: :..:.: :
CCDS56 AIIDPLIYAFHSQELRRTLKEVLTCSW
300 310
>>CCDS11869.1 MC2R gene_id:4158|Hs108|chr18 (297 aa)
initn: 951 init1: 583 opt: 583 Z-score: 443.4 bits: 90.3 E(32554): 2.2e-18
Smith-Waterman score: 940; 47.9% identity (79.8% similar) in 282 aa overlap (72-352:21-293)
50 60 70 80 90 100
pF1KE0 CCLPSVQPTLPNGSEHLQAPFFSNQSSSAFCEQVFIKPEVFLSLGIVSLLENILVILAVV
: .: . :.:....::..:::..:.:::
CCDS11 MKHIINSYENINNTARNNSDCPRVVLPEEIFFTISIVGVLENLIVLLAVF
10 20 30 40 50
110 120 130 140 150 160
pF1KE0 RNGNLHSPMYFFLCSLAVADMLVSVSNALETIMIAIVHSDYLTFEDQFIQHMDNIFDSMI
.: ::..:::::.::::..::: :. . ::.:.: . . :: . .: :.:.::..
CCDS11 KNKNLQAPMYFFICSLAISDMLGSLYKILENILIILRNMGYLKPRGSFETTADDIIDSLF
60 70 80 90 100 110
170 180 190 200 210 220
pF1KE0 CISLVASICNLLAIAVDRYVTIFYALRYHSIMTVRKALTLIVAIWVCCGVCGVVFIVYSE
.::..:: .: .::.:::.:::.:::::::.:.:........::. : :......:.
CCDS11 VLSLLGSIFSLSVIAADRYITIFHALRYHSIVTMRRTVVVLTVIWTFCTGTGITMVIFSH
120 130 140 150 160 170
230 240 250 260 270 280
pF1KE0 SKMVIVCLITMFFAMMLLMGTLYVHMFLFARLHVKRIAALPPADGVAPQQHSCMKGAVTI
... . ..: :.... :::::::.:: :...:..:: :. ::::.:.
CCDS11 HVPTVITFTSLFPLMLVFILCLYVHMFLLARSHTRKISTLPRAN---------MKGAITL
180 190 200 210 220
290 300 310 320 330 340
pF1KE0 TILLGVFIFCWAPFFLHLVLIITCPTNPYCICYTAHFNTYLVLIMCNSVIDPLIYAFRSL
:::::::::::::: ::..:. ::.:::: :: . :.. .:::::.::::.::::::
CCDS11 TILLGVFIFCWAPFVLHVLLMTFCPSNPYCACYMSLFQVNGMLIMCNAVIDPFIYAFRSP
230 240 250 260 270 280
350 360
pF1KE0 ELRNTFRE-ILCGCNGMNLG
:::..:.. :.:
CCDS11 ELRDAFKKMIFCSRYW
290
360 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sat Nov 5 03:14:45 2016 done: Sat Nov 5 03:14:45 2016
Total Scan time: 2.080 Total Display time: -0.010
Function used was FASTA [36.3.4 Apr, 2011]