FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KE0295, 236 aa
  1>>>pF1KE0295 236 - 236 aa - 236 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 4.6646+/-0.000328; mu= 17.4862+/- 0.020
 mean_var=58.7410+/-11.815, 0's: 0 Z-trim(115.7): 32  B-trim: 65 in 1/52
 Lambda= 0.167341
 statistics sampled from 26301 (26330) to 26301 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.69), E-opt: 0.2 (0.309), width:  16
 Scan time:  7.050

The best scores are:                                      opt bits E(85289)
NP_542432 (OMIM: 300370) three prime repair exonuc ( 236) 1592 392.3 3.9e-109
NP_009179 (OMIM: 152700,192315,225750,606609,61044 ( 304)  605 154.1 2.6e-37
NP_338599 (OMIM: 152700,192315,225750,606609,61044 ( 314)  605 154.1 2.6e-37
NP_057465 (OMIM: 152700,192315,225750,606609,61044 ( 369)  605 154.1   3e-37


>>NP_542432 (OMIM: 300370) three prime repair exonucleas  (236 aa)
 initn: 1592 init1: 1592 opt: 1592  Z-score: 2080.3  bits: 392.3 E(85289): 3.9e-109
Smith-Waterman score: 1592; 100.0% identity (100.0% similar) in 236 aa overlap (1-236:1-236)

               10        20        30        40        50        60
pF1KE0 MSEAPRAETFVFLDLEATGLPSVEPEIAELSLFAVHRSSLENPEHDESGALVLPRVLDKL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_542 MSEAPRAETFVFLDLEATGLPSVEPEIAELSLFAVHRSSLENPEHDESGALVLPRVLDKL
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE0 TLCMCPERPFTAKASEITGLSSEGLARCRKAGFDGAVVRTLQAFLSRQAGPICLVAHNGF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_542 TLCMCPERPFTAKASEITGLSSEGLARCRKAGFDGAVVRTLQAFLSRQAGPICLVAHNGF
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KE0 DYDFPLLCAELRRLGARLPRDTVCLDTLPALRGLDRAHSHGTRARGRQGYSLGSLFHRYF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_542 DYDFPLLCAELRRLGARLPRDTVCLDTLPALRGLDRAHSHGTRARGRQGYSLGSLFHRYF
              130       140       150       160       170       180

              190       200       210       220       230      
pF1KE0 RAEPSAAHSAEGDVHTLLLIFLHRAAELLAWADEQARGWAHIEPMYLPPDDPSLEA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_542 RAEPSAAHSAEGDVHTLLLIFLHRAAELLAWADEQARGWAHIEPMYLPPDDPSLEA
              190       200       210       220       230      

>>NP_009179 (OMIM: 152700,192315,225750,606609,610448) t  (304 aa)
 initn: 412 init1: 412 opt: 605  Z-score: 790.9  bits: 154.1 E(85289): 2.6e-37
Smith-Waterman score: 605; 46.2% identity (68.2% similar) in 223 aa overlap (8-226:2-223)

               10        20        30        40        50          
pF1KE0 MSEAPRAETFVFLDLEATGLPSVEPEIAELSLFAVHRSSLENPEHDESGALVLP---RVL
              .:..:.:.::::::  .:...:: :.:::: .::.:  ...   ..:   ::.
NP_009       MQTLIFFDMEATGLPFSQPKVTELCLLAVHRCALESPPTSQGPPPTVPPPPRVV
                     10        20        30        40        50    

        60        70        80        90       100       110       
pF1KE0 DKLTLCMCPERPFTAKASEITGLSSEGLARCRKAGFDGAVVRTLQAFLSRQAGPICLVAH
       :::.::. : .  .  ::::::::.  ::   .  ::  ..  : ::: ::  : :::::
NP_009 DKLSLCVAPGKACSPAASEITGLSTAVLAAHGRQCFDDNLANLLLAFLRRQPQPWCLVAH
           60        70        80        90       100       110    

       120       130       140        150       160       170      
pF1KE0 NGFDYDFPLLCAELRRLGARLPRD-TVCLDTLPALRGLDRAHSHGTRARGRQGYSLGSLF
       ::  :::::: :::  ::     : . :.:.. ::..:.:: : . ..  :..:::::..
NP_009 NGDRYDFPLLQAELAMLGLTSALDGAFCVDSITALKALERASSPSEHG-PRKSYSLGSIY
          120       130       140       150       160        170   

        180       190       200       210       220       230      
pF1KE0 HRYFRAEPSAAHSAEGDVHTLLLIFLHRAAELLAWADEQARGWAHIEPMYLPPDDPSLEA
        : .   :  .:.::::: .:: :   :   :: :.: .:: .. :.:::          
NP_009 TRLYGQSPPDSHTAEGDVLALLSICQWRPQALLRWVDAHARPFGTIRPMYGVTASARTKP
           180       190       200       210       220       230   

NP_009 RPSAVTTTAHLATTRNTSPSLGESRGTKDLPPVKDPGALSREGLLAPLGLLAILTLAVAT
           240       250       260       270       280       290   

>>NP_338599 (OMIM: 152700,192315,225750,606609,610448) t  (314 aa)
 initn: 412 init1: 412 opt: 605  Z-score: 790.7  bits: 154.1 E(85289): 2.6e-37
Smith-Waterman score: 605; 46.2% identity (68.2% similar) in 223 aa overlap (8-226:12-233)

                   10        20        30        40        50      
pF1KE0     MSEAPRAETFVFLDLEATGLPSVEPEIAELSLFAVHRSSLENPEHDESGALVLP--
                  .:..:.:.::::::  .:...:: :.:::: .::.:  ...   ..:  
NP_338 MGSQALPPGPMQTLIFFDMEATGLPFSQPKVTELCLLAVHRCALESPPTSQGPPPTVPPP
               10        20        30        40        50        60

            60        70        80        90       100       110   
pF1KE0 -RVLDKLTLCMCPERPFTAKASEITGLSSEGLARCRKAGFDGAVVRTLQAFLSRQAGPIC
        ::.:::.::. : .  .  ::::::::.  ::   .  ::  ..  : ::: ::  : :
NP_338 PRVVDKLSLCVAPGKACSPAASEITGLSTAVLAAHGRQCFDDNLANLLLAFLRRQPQPWC
               70        80        90       100       110       120

           120       130       140        150       160       170  
pF1KE0 LVAHNGFDYDFPLLCAELRRLGARLPRD-TVCLDTLPALRGLDRAHSHGTRARGRQGYSL
       ::::::  :::::: :::  ::     : . :.:.. ::..:.:: : . ..  :..:::
NP_338 LVAHNGDRYDFPLLQAELAMLGLTSALDGAFCVDSITALKALERASSPSEHG-PRKSYSL
              130       140       150       160       170          

            180       190       200       210       220       230  
pF1KE0 GSLFHRYFRAEPSAAHSAEGDVHTLLLIFLHRAAELLAWADEQARGWAHIEPMYLPPDDP
       ::.. : .   :  .:.::::: .:: :   :   :: :.: .:: .. :.:::      
NP_338 GSIYTRLYGQSPPDSHTAEGDVLALLSICQWRPQALLRWVDAHARPFGTIRPMYGVTASA
     180       190       200       210       220       230         

                                                                   
pF1KE0 SLEA                                                        
                                                                   
NP_338 RTKPRPSAVTTTAHLATTRNTSPSLGESRGTKDLPPVKDPGALSREGLLAPLGLLAILTL
     240       250       260       270       280       290         

>>NP_057465 (OMIM: 152700,192315,225750,606609,610448) t  (369 aa)
 initn: 412 init1: 412 opt: 605  Z-score: 789.8  bits: 154.1 E(85289): 3e-37
Smith-Waterman score: 605; 46.2% identity (68.2% similar) in 223 aa overlap (8-226:67-288)

                                      10        20        30       
pF1KE0                        MSEAPRAETFVFLDLEATGLPSVEPEIAELSLFAVHR
                                     .:..:.:.::::::  .:...:: :.::::
NP_057 THTPTPCSSPGSAAGTYPTMGSQALPPGPMQTLIFFDMEATGLPFSQPKVTELCLLAVHR
         40        50        60        70        80        90      

        40        50           60        70        80        90    
pF1KE0 SSLENPEHDESGALVLP---RVLDKLTLCMCPERPFTAKASEITGLSSEGLARCRKAGFD
        .::.:  ...   ..:   ::.:::.::. : .  .  ::::::::.  ::   .  ::
NP_057 CALESPPTSQGPPPTVPPPPRVVDKLSLCVAPGKACSPAASEITGLSTAVLAAHGRQCFD
        100       110       120       130       140       150      

          100       110       120       130       140        150   
pF1KE0 GAVVRTLQAFLSRQAGPICLVAHNGFDYDFPLLCAELRRLGARLPRD-TVCLDTLPALRG
         ..  : ::: ::  : :::::::  :::::: :::  ::     : . :.:.. ::..
NP_057 DNLANLLLAFLRRQPQPWCLVAHNGDRYDFPLLQAELAMLGLTSALDGAFCVDSITALKA
        160       170       180       190       200       210      

           160       170       180       190       200       210   
pF1KE0 LDRAHSHGTRARGRQGYSLGSLFHRYFRAEPSAAHSAEGDVHTLLLIFLHRAAELLAWAD
       :.:: : . ..  :..:::::.. : .   :  .:.::::: .:: :   :   :: :.:
NP_057 LERASSPSEHG-PRKSYSLGSIYTRLYGQSPPDSHTAEGDVLALLSICQWRPQALLRWVD
        220        230       240       250       260       270     

           220       230                                           
pF1KE0 EQARGWAHIEPMYLPPDDPSLEA                                     
        .:: .. :.:::                                               
NP_057 AHARPFGTIRPMYGVTASARTKPRPSAVTTTAHLATTRNTSPSLGESRGTKDLPPVKDPG
         280       290       300       310       320       330     




236 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Thu Nov  3 17:28:41 2016 done: Thu Nov  3 17:28:42 2016
 Total Scan time:  7.050 Total Display time: -0.030

Function used was FASTA [36.3.4 Apr, 2011]