Result of FASTA (omim) for
pFN21AB5080
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB5080, 725 aa
1>>>pF1KB5080 725 - 725 aa - 725 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.8865+/-0.000471; mu= 16.1852+/- 0.029
mean_var=77.5677+/-16.207, 0's: 0 Z-trim(110.1): 74 B-trim: 756 in 1/53
Lambda= 0.145624
statistics sampled from 18341 (18415) to 18341 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.565), E-opt: 0.2 (0.216), width: 16
Scan time: 10.460
The best scores are: opt bits E(85289)
NP_064551 (OMIM: 210200,609010) methylcrotonoyl-Co ( 725) 4715 1001.1 0
XP_011511294 (OMIM: 210200,609010) PREDICTED: meth ( 687) 4456 946.7 0
XP_016862364 (OMIM: 210200,609010) PREDICTED: meth ( 616) 4008 852.5 0
XP_016862363 (OMIM: 210200,609010) PREDICTED: meth ( 616) 4008 852.5 0
XP_006713765 (OMIM: 210200,609010) PREDICTED: meth ( 616) 4008 852.5 0
NP_001280202 (OMIM: 210200,609010) methylcrotonoyl ( 608) 3647 776.7 0
XP_011511295 (OMIM: 210200,609010) PREDICTED: meth ( 472) 3023 645.5 1.4e-184
NP_001121164 (OMIM: 232000,606054) propionyl-CoA c ( 702) 1603 347.3 1.3e-94
XP_016876098 (OMIM: 232000,606054) PREDICTED: prop ( 695) 1592 345.0 6.2e-94
NP_000273 (OMIM: 232000,606054) propionyl-CoA carb ( 728) 1592 345.0 6.4e-94
XP_016876103 (OMIM: 232000,606054) PREDICTED: prop ( 655) 1483 322.0 4.6e-87
XP_016876095 (OMIM: 232000,606054) PREDICTED: prop ( 718) 1483 322.1 5e-87
XP_005254116 (OMIM: 232000,606054) PREDICTED: prop ( 640) 1472 319.7 2.2e-86
XP_016876102 (OMIM: 232000,606054) PREDICTED: prop ( 669) 1472 319.7 2.3e-86
XP_016876101 (OMIM: 232000,606054) PREDICTED: prop ( 681) 1472 319.7 2.4e-86
NP_001171475 (OMIM: 232000,606054) propionyl-CoA c ( 681) 1472 319.7 2.4e-86
XP_016876100 (OMIM: 232000,606054) PREDICTED: prop ( 683) 1472 319.7 2.4e-86
XP_011519395 (OMIM: 232000,606054) PREDICTED: prop ( 699) 1472 319.7 2.4e-86
XP_016876097 (OMIM: 232000,606054) PREDICTED: prop ( 710) 1472 319.8 2.4e-86
XP_016876096 (OMIM: 232000,606054) PREDICTED: prop ( 711) 1472 319.8 2.4e-86
XP_016876094 (OMIM: 232000,606054) PREDICTED: prop ( 744) 1472 319.8 2.5e-86
XP_016876104 (OMIM: 232000,606054) PREDICTED: prop ( 624) 1470 319.3 2.9e-86
XP_016876105 (OMIM: 232000,606054) PREDICTED: prop ( 551) 1469 319.1 3e-86
XP_016876099 (OMIM: 232000,606054) PREDICTED: prop ( 689) 1308 285.3 5.6e-76
XP_016873361 (OMIM: 266150,608786) PREDICTED: pyru (1178) 1299 283.5 3.3e-75
XP_016873358 (OMIM: 266150,608786) PREDICTED: pyru (1178) 1299 283.5 3.3e-75
NP_001035806 (OMIM: 266150,608786) pyruvate carbox (1178) 1299 283.5 3.3e-75
XP_011543388 (OMIM: 266150,608786) PREDICTED: pyru (1178) 1299 283.5 3.3e-75
XP_016873357 (OMIM: 266150,608786) PREDICTED: pyru (1178) 1299 283.5 3.3e-75
XP_016873360 (OMIM: 266150,608786) PREDICTED: pyru (1178) 1299 283.5 3.3e-75
XP_005274089 (OMIM: 266150,608786) PREDICTED: pyru (1178) 1299 283.5 3.3e-75
NP_000911 (OMIM: 266150,608786) pyruvate carboxyla (1178) 1299 283.5 3.3e-75
XP_005274088 (OMIM: 266150,608786) PREDICTED: pyru (1178) 1299 283.5 3.3e-75
NP_071504 (OMIM: 266150,608786) pyruvate carboxyla (1178) 1299 283.5 3.3e-75
XP_016873359 (OMIM: 266150,608786) PREDICTED: pyru (1178) 1299 283.5 3.3e-75
XP_006718641 (OMIM: 266150,608786) PREDICTED: pyru (1178) 1299 283.5 3.3e-75
XP_016876106 (OMIM: 232000,606054) PREDICTED: prop ( 413) 682 153.7 1.4e-36
XP_016876107 (OMIM: 232000,606054) PREDICTED: prop ( 395) 562 128.4 5.3e-29
XP_011536567 (OMIM: 601557) PREDICTED: acetyl-CoA (1304) 541 124.3 3.1e-27
XP_016874741 (OMIM: 601557) PREDICTED: acetyl-CoA (2193) 541 124.4 4.9e-27
XP_011536566 (OMIM: 601557) PREDICTED: acetyl-CoA (2249) 541 124.4 5e-27
XP_006719430 (OMIM: 601557) PREDICTED: acetyl-CoA (2256) 541 124.4 5e-27
XP_011536565 (OMIM: 601557) PREDICTED: acetyl-CoA (2395) 541 124.4 5.2e-27
NP_001084 (OMIM: 601557) acetyl-CoA carboxylase 2 (2458) 541 124.4 5.4e-27
XP_005253933 (OMIM: 601557) PREDICTED: acetyl-CoA (2458) 541 124.4 5.4e-27
XP_011536561 (OMIM: 601557) PREDICTED: acetyl-CoA (2458) 541 124.4 5.4e-27
XP_011523006 (OMIM: 200350,613933) PREDICTED: acet (2268) 534 122.9 1.4e-26
XP_005257324 (OMIM: 200350,613933) PREDICTED: acet (2268) 534 122.9 1.4e-26
NP_942135 (OMIM: 200350,613933) acetyl-CoA carboxy (2268) 534 122.9 1.4e-26
NP_942134 (OMIM: 200350,613933) acetyl-CoA carboxy (2288) 534 122.9 1.4e-26
>>NP_064551 (OMIM: 210200,609010) methylcrotonoyl-CoA ca (725 aa)
initn: 4715 init1: 4715 opt: 4715 Z-score: 5353.1 bits: 1001.1 E(85289): 0
Smith-Waterman score: 4715; 99.7% identity (99.7% similar) in 725 aa overlap (1-725:1-725)
10 20 30 40 50 60
pF1KB5 MAAASAVSVLLVAAERNRWHRLPSLLLPPRTWVWRQRTMKYTTATGRNITKVLIANRGEI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_064 MAAASAVSVLLVAAERNRWHRLPSLLLPPRTWVWRQRTMKYTTATGRNITKVLIANRGEI
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB5 ACRVMRTAKKLGVQTVAVYSEADRNSMHVDMADEAYSIGPAPSQQSYLSMEKIIQVAKTS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_064 ACRVMRTAKKLGVQTVAVYSEADRNSMHVDMADEAYSIGPAPSQQSYLSMEKIIQVAKTS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB5 AAQAIHPGCGFLSENMEFAELCKQEGIIFIGPPPSAIRDMGIKSTSKSIMAAAGVPVVEG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_064 AAQAIHPGCGFLSENMEFAELCKQEGIIFIGPPPSAIRDMGIKSTSKSIMAAAGVPVVEG
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB5 YHGEDQSDQCLKEHARRIGYPVMIKAVRGGGGKGMRIVRSEQEFQEQLESAWREAKKSFN
::::::::::::::::::::::::::::::::::::::::::::::::::: ::::::::
NP_064 YHGEDQSDQCLKEHARRIGYPVMIKAVRGGGGKGMRIVRSEQEFQEQLESARREAKKSFN
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB5 DDAMLIEKFVDTPRHVEVQVFGDHHGNAVYLFERDCSVQRRHQKIIEEAPAPGIKSEVRK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_064 DDAMLIEKFVDTPRHVEVQVFGDHHGNAVYLFERDCSVQRRHQKIIEEAPAPGIKSEVRK
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB5 KLGEAAVRAAKAVNYVGAGTVEFIMDSKHNFCFMEMNTRLQVEHPVTEMITGTDLVEWQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_064 KLGEAAVRAAKAVNYVGAGTVEFIMDSKHNFCFMEMNTRLQVEHPVTEMITGTDLVEWQL
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB5 RIAAGEKIPLSQEEITLQGHAFEARIYAEDPSNNFMPVAGPLVHLSTPRADPSTRIETGV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_064 RIAAGEKIPLSQEEITLQGHAFEARIYAEDPSNNFMPVAGPLVHLSTPRADPSTRIETGV
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB5 RQGDEVSVHYDPMIAKLVVWAADRQAALTKLRYSLRQYNIVGLPTNIDFLLNLSGHPEFE
::::::::::::::::::::::::::::::::::::::::::: ::::::::::::::::
NP_064 RQGDEVSVHYDPMIAKLVVWAADRQAALTKLRYSLRQYNIVGLHTNIDFLLNLSGHPEFE
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB5 AGNVHTDFIPQHHKQLLLSRKAAAKESLCQAALGLILKEKAMTDTFTLQAHDQFSPFSSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_064 AGNVHTDFIPQHHKQLLLSRKAAAKESLCQAALGLILKEKAMTDTFTLQAHDQFSPFSSS
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB5 SGRRLNISYTRNMTLKDGKNNVAIAVTYNHDGSYSMQIEDKTFQVLGNLYSEGDCTYLKC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_064 SGRRLNISYTRNMTLKDGKNNVAIAVTYNHDGSYSMQIEDKTFQVLGNLYSEGDCTYLKC
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB5 SVNGVASKAKLIILENTIYLFSKEGSIEIDIPVPKYLSSVSSQETQGGPLAPMTGTIEKV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_064 SVNGVASKAKLIILENTIYLFSKEGSIEIDIPVPKYLSSVSSQETQGGPLAPMTGTIEKV
610 620 630 640 650 660
670 680 690 700 710 720
pF1KB5 FVKAGDKVKAGDSLMVMIAMKMEHTIKSPKDGTVKKVFYREGAQANRHTPLVEFEEEESD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_064 FVKAGDKVKAGDSLMVMIAMKMEHTIKSPKDGTVKKVFYREGAQANRHTPLVEFEEEESD
670 680 690 700 710 720
pF1KB5 KRESE
:::::
NP_064 KRESE
>>XP_011511294 (OMIM: 210200,609010) PREDICTED: methylcr (687 aa)
initn: 4456 init1: 4456 opt: 4456 Z-score: 5059.4 bits: 946.7 E(85289): 0
Smith-Waterman score: 4456; 99.7% identity (99.7% similar) in 687 aa overlap (39-725:1-687)
10 20 30 40 50 60
pF1KB5 VLLVAAERNRWHRLPSLLLPPRTWVWRQRTMKYTTATGRNITKVLIANRGEIACRVMRTA
::::::::::::::::::::::::::::::
XP_011 MKYTTATGRNITKVLIANRGEIACRVMRTA
10 20 30
70 80 90 100 110 120
pF1KB5 KKLGVQTVAVYSEADRNSMHVDMADEAYSIGPAPSQQSYLSMEKIIQVAKTSAAQAIHPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KKLGVQTVAVYSEADRNSMHVDMADEAYSIGPAPSQQSYLSMEKIIQVAKTSAAQAIHPG
40 50 60 70 80 90
130 140 150 160 170 180
pF1KB5 CGFLSENMEFAELCKQEGIIFIGPPPSAIRDMGIKSTSKSIMAAAGVPVVEGYHGEDQSD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CGFLSENMEFAELCKQEGIIFIGPPPSAIRDMGIKSTSKSIMAAAGVPVVEGYHGEDQSD
100 110 120 130 140 150
190 200 210 220 230 240
pF1KB5 QCLKEHARRIGYPVMIKAVRGGGGKGMRIVRSEQEFQEQLESAWREAKKSFNDDAMLIEK
::::::::::::::::::::::::::::::::::::::::::: ::::::::::::::::
XP_011 QCLKEHARRIGYPVMIKAVRGGGGKGMRIVRSEQEFQEQLESARREAKKSFNDDAMLIEK
160 170 180 190 200 210
250 260 270 280 290 300
pF1KB5 FVDTPRHVEVQVFGDHHGNAVYLFERDCSVQRRHQKIIEEAPAPGIKSEVRKKLGEAAVR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FVDTPRHVEVQVFGDHHGNAVYLFERDCSVQRRHQKIIEEAPAPGIKSEVRKKLGEAAVR
220 230 240 250 260 270
310 320 330 340 350 360
pF1KB5 AAKAVNYVGAGTVEFIMDSKHNFCFMEMNTRLQVEHPVTEMITGTDLVEWQLRIAAGEKI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AAKAVNYVGAGTVEFIMDSKHNFCFMEMNTRLQVEHPVTEMITGTDLVEWQLRIAAGEKI
280 290 300 310 320 330
370 380 390 400 410 420
pF1KB5 PLSQEEITLQGHAFEARIYAEDPSNNFMPVAGPLVHLSTPRADPSTRIETGVRQGDEVSV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PLSQEEITLQGHAFEARIYAEDPSNNFMPVAGPLVHLSTPRADPSTRIETGVRQGDEVSV
340 350 360 370 380 390
430 440 450 460 470 480
pF1KB5 HYDPMIAKLVVWAADRQAALTKLRYSLRQYNIVGLPTNIDFLLNLSGHPEFEAGNVHTDF
::::::::::::::::::::::::::::::::::: ::::::::::::::::::::::::
XP_011 HYDPMIAKLVVWAADRQAALTKLRYSLRQYNIVGLHTNIDFLLNLSGHPEFEAGNVHTDF
400 410 420 430 440 450
490 500 510 520 530 540
pF1KB5 IPQHHKQLLLSRKAAAKESLCQAALGLILKEKAMTDTFTLQAHDQFSPFSSSSGRRLNIS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IPQHHKQLLLSRKAAAKESLCQAALGLILKEKAMTDTFTLQAHDQFSPFSSSSGRRLNIS
460 470 480 490 500 510
550 560 570 580 590 600
pF1KB5 YTRNMTLKDGKNNVAIAVTYNHDGSYSMQIEDKTFQVLGNLYSEGDCTYLKCSVNGVASK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YTRNMTLKDGKNNVAIAVTYNHDGSYSMQIEDKTFQVLGNLYSEGDCTYLKCSVNGVASK
520 530 540 550 560 570
610 620 630 640 650 660
pF1KB5 AKLIILENTIYLFSKEGSIEIDIPVPKYLSSVSSQETQGGPLAPMTGTIEKVFVKAGDKV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AKLIILENTIYLFSKEGSIEIDIPVPKYLSSVSSQETQGGPLAPMTGTIEKVFVKAGDKV
580 590 600 610 620 630
670 680 690 700 710 720
pF1KB5 KAGDSLMVMIAMKMEHTIKSPKDGTVKKVFYREGAQANRHTPLVEFEEEESDKRESE
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KAGDSLMVMIAMKMEHTIKSPKDGTVKKVFYREGAQANRHTPLVEFEEEESDKRESE
640 650 660 670 680
>>XP_016862364 (OMIM: 210200,609010) PREDICTED: methylcr (616 aa)
initn: 4008 init1: 4008 opt: 4008 Z-score: 4551.4 bits: 852.5 E(85289): 0
Smith-Waterman score: 4008; 99.7% identity (99.7% similar) in 616 aa overlap (110-725:1-616)
80 90 100 110 120 130
pF1KB5 SEADRNSMHVDMADEAYSIGPAPSQQSYLSMEKIIQVAKTSAAQAIHPGCGFLSENMEFA
::::::::::::::::::::::::::::::
XP_016 MEKIIQVAKTSAAQAIHPGCGFLSENMEFA
10 20 30
140 150 160 170 180 190
pF1KB5 ELCKQEGIIFIGPPPSAIRDMGIKSTSKSIMAAAGVPVVEGYHGEDQSDQCLKEHARRIG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ELCKQEGIIFIGPPPSAIRDMGIKSTSKSIMAAAGVPVVEGYHGEDQSDQCLKEHARRIG
40 50 60 70 80 90
200 210 220 230 240 250
pF1KB5 YPVMIKAVRGGGGKGMRIVRSEQEFQEQLESAWREAKKSFNDDAMLIEKFVDTPRHVEVQ
:::::::::::::::::::::::::::::::: :::::::::::::::::::::::::::
XP_016 YPVMIKAVRGGGGKGMRIVRSEQEFQEQLESARREAKKSFNDDAMLIEKFVDTPRHVEVQ
100 110 120 130 140 150
260 270 280 290 300 310
pF1KB5 VFGDHHGNAVYLFERDCSVQRRHQKIIEEAPAPGIKSEVRKKLGEAAVRAAKAVNYVGAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VFGDHHGNAVYLFERDCSVQRRHQKIIEEAPAPGIKSEVRKKLGEAAVRAAKAVNYVGAG
160 170 180 190 200 210
320 330 340 350 360 370
pF1KB5 TVEFIMDSKHNFCFMEMNTRLQVEHPVTEMITGTDLVEWQLRIAAGEKIPLSQEEITLQG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TVEFIMDSKHNFCFMEMNTRLQVEHPVTEMITGTDLVEWQLRIAAGEKIPLSQEEITLQG
220 230 240 250 260 270
380 390 400 410 420 430
pF1KB5 HAFEARIYAEDPSNNFMPVAGPLVHLSTPRADPSTRIETGVRQGDEVSVHYDPMIAKLVV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HAFEARIYAEDPSNNFMPVAGPLVHLSTPRADPSTRIETGVRQGDEVSVHYDPMIAKLVV
280 290 300 310 320 330
440 450 460 470 480 490
pF1KB5 WAADRQAALTKLRYSLRQYNIVGLPTNIDFLLNLSGHPEFEAGNVHTDFIPQHHKQLLLS
:::::::::::::::::::::::: :::::::::::::::::::::::::::::::::::
XP_016 WAADRQAALTKLRYSLRQYNIVGLHTNIDFLLNLSGHPEFEAGNVHTDFIPQHHKQLLLS
340 350 360 370 380 390
500 510 520 530 540 550
pF1KB5 RKAAAKESLCQAALGLILKEKAMTDTFTLQAHDQFSPFSSSSGRRLNISYTRNMTLKDGK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RKAAAKESLCQAALGLILKEKAMTDTFTLQAHDQFSPFSSSSGRRLNISYTRNMTLKDGK
400 410 420 430 440 450
560 570 580 590 600 610
pF1KB5 NNVAIAVTYNHDGSYSMQIEDKTFQVLGNLYSEGDCTYLKCSVNGVASKAKLIILENTIY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NNVAIAVTYNHDGSYSMQIEDKTFQVLGNLYSEGDCTYLKCSVNGVASKAKLIILENTIY
460 470 480 490 500 510
620 630 640 650 660 670
pF1KB5 LFSKEGSIEIDIPVPKYLSSVSSQETQGGPLAPMTGTIEKVFVKAGDKVKAGDSLMVMIA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LFSKEGSIEIDIPVPKYLSSVSSQETQGGPLAPMTGTIEKVFVKAGDKVKAGDSLMVMIA
520 530 540 550 560 570
680 690 700 710 720
pF1KB5 MKMEHTIKSPKDGTVKKVFYREGAQANRHTPLVEFEEEESDKRESE
::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MKMEHTIKSPKDGTVKKVFYREGAQANRHTPLVEFEEEESDKRESE
580 590 600 610
>>XP_016862363 (OMIM: 210200,609010) PREDICTED: methylcr (616 aa)
initn: 4008 init1: 4008 opt: 4008 Z-score: 4551.4 bits: 852.5 E(85289): 0
Smith-Waterman score: 4008; 99.7% identity (99.7% similar) in 616 aa overlap (110-725:1-616)
80 90 100 110 120 130
pF1KB5 SEADRNSMHVDMADEAYSIGPAPSQQSYLSMEKIIQVAKTSAAQAIHPGCGFLSENMEFA
::::::::::::::::::::::::::::::
XP_016 MEKIIQVAKTSAAQAIHPGCGFLSENMEFA
10 20 30
140 150 160 170 180 190
pF1KB5 ELCKQEGIIFIGPPPSAIRDMGIKSTSKSIMAAAGVPVVEGYHGEDQSDQCLKEHARRIG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ELCKQEGIIFIGPPPSAIRDMGIKSTSKSIMAAAGVPVVEGYHGEDQSDQCLKEHARRIG
40 50 60 70 80 90
200 210 220 230 240 250
pF1KB5 YPVMIKAVRGGGGKGMRIVRSEQEFQEQLESAWREAKKSFNDDAMLIEKFVDTPRHVEVQ
:::::::::::::::::::::::::::::::: :::::::::::::::::::::::::::
XP_016 YPVMIKAVRGGGGKGMRIVRSEQEFQEQLESARREAKKSFNDDAMLIEKFVDTPRHVEVQ
100 110 120 130 140 150
260 270 280 290 300 310
pF1KB5 VFGDHHGNAVYLFERDCSVQRRHQKIIEEAPAPGIKSEVRKKLGEAAVRAAKAVNYVGAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VFGDHHGNAVYLFERDCSVQRRHQKIIEEAPAPGIKSEVRKKLGEAAVRAAKAVNYVGAG
160 170 180 190 200 210
320 330 340 350 360 370
pF1KB5 TVEFIMDSKHNFCFMEMNTRLQVEHPVTEMITGTDLVEWQLRIAAGEKIPLSQEEITLQG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TVEFIMDSKHNFCFMEMNTRLQVEHPVTEMITGTDLVEWQLRIAAGEKIPLSQEEITLQG
220 230 240 250 260 270
380 390 400 410 420 430
pF1KB5 HAFEARIYAEDPSNNFMPVAGPLVHLSTPRADPSTRIETGVRQGDEVSVHYDPMIAKLVV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HAFEARIYAEDPSNNFMPVAGPLVHLSTPRADPSTRIETGVRQGDEVSVHYDPMIAKLVV
280 290 300 310 320 330
440 450 460 470 480 490
pF1KB5 WAADRQAALTKLRYSLRQYNIVGLPTNIDFLLNLSGHPEFEAGNVHTDFIPQHHKQLLLS
:::::::::::::::::::::::: :::::::::::::::::::::::::::::::::::
XP_016 WAADRQAALTKLRYSLRQYNIVGLHTNIDFLLNLSGHPEFEAGNVHTDFIPQHHKQLLLS
340 350 360 370 380 390
500 510 520 530 540 550
pF1KB5 RKAAAKESLCQAALGLILKEKAMTDTFTLQAHDQFSPFSSSSGRRLNISYTRNMTLKDGK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RKAAAKESLCQAALGLILKEKAMTDTFTLQAHDQFSPFSSSSGRRLNISYTRNMTLKDGK
400 410 420 430 440 450
560 570 580 590 600 610
pF1KB5 NNVAIAVTYNHDGSYSMQIEDKTFQVLGNLYSEGDCTYLKCSVNGVASKAKLIILENTIY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NNVAIAVTYNHDGSYSMQIEDKTFQVLGNLYSEGDCTYLKCSVNGVASKAKLIILENTIY
460 470 480 490 500 510
620 630 640 650 660 670
pF1KB5 LFSKEGSIEIDIPVPKYLSSVSSQETQGGPLAPMTGTIEKVFVKAGDKVKAGDSLMVMIA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LFSKEGSIEIDIPVPKYLSSVSSQETQGGPLAPMTGTIEKVFVKAGDKVKAGDSLMVMIA
520 530 540 550 560 570
680 690 700 710 720
pF1KB5 MKMEHTIKSPKDGTVKKVFYREGAQANRHTPLVEFEEEESDKRESE
::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MKMEHTIKSPKDGTVKKVFYREGAQANRHTPLVEFEEEESDKRESE
580 590 600 610
>>XP_006713765 (OMIM: 210200,609010) PREDICTED: methylcr (616 aa)
initn: 4008 init1: 4008 opt: 4008 Z-score: 4551.4 bits: 852.5 E(85289): 0
Smith-Waterman score: 4008; 99.7% identity (99.7% similar) in 616 aa overlap (110-725:1-616)
80 90 100 110 120 130
pF1KB5 SEADRNSMHVDMADEAYSIGPAPSQQSYLSMEKIIQVAKTSAAQAIHPGCGFLSENMEFA
::::::::::::::::::::::::::::::
XP_006 MEKIIQVAKTSAAQAIHPGCGFLSENMEFA
10 20 30
140 150 160 170 180 190
pF1KB5 ELCKQEGIIFIGPPPSAIRDMGIKSTSKSIMAAAGVPVVEGYHGEDQSDQCLKEHARRIG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 ELCKQEGIIFIGPPPSAIRDMGIKSTSKSIMAAAGVPVVEGYHGEDQSDQCLKEHARRIG
40 50 60 70 80 90
200 210 220 230 240 250
pF1KB5 YPVMIKAVRGGGGKGMRIVRSEQEFQEQLESAWREAKKSFNDDAMLIEKFVDTPRHVEVQ
:::::::::::::::::::::::::::::::: :::::::::::::::::::::::::::
XP_006 YPVMIKAVRGGGGKGMRIVRSEQEFQEQLESARREAKKSFNDDAMLIEKFVDTPRHVEVQ
100 110 120 130 140 150
260 270 280 290 300 310
pF1KB5 VFGDHHGNAVYLFERDCSVQRRHQKIIEEAPAPGIKSEVRKKLGEAAVRAAKAVNYVGAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 VFGDHHGNAVYLFERDCSVQRRHQKIIEEAPAPGIKSEVRKKLGEAAVRAAKAVNYVGAG
160 170 180 190 200 210
320 330 340 350 360 370
pF1KB5 TVEFIMDSKHNFCFMEMNTRLQVEHPVTEMITGTDLVEWQLRIAAGEKIPLSQEEITLQG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 TVEFIMDSKHNFCFMEMNTRLQVEHPVTEMITGTDLVEWQLRIAAGEKIPLSQEEITLQG
220 230 240 250 260 270
380 390 400 410 420 430
pF1KB5 HAFEARIYAEDPSNNFMPVAGPLVHLSTPRADPSTRIETGVRQGDEVSVHYDPMIAKLVV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 HAFEARIYAEDPSNNFMPVAGPLVHLSTPRADPSTRIETGVRQGDEVSVHYDPMIAKLVV
280 290 300 310 320 330
440 450 460 470 480 490
pF1KB5 WAADRQAALTKLRYSLRQYNIVGLPTNIDFLLNLSGHPEFEAGNVHTDFIPQHHKQLLLS
:::::::::::::::::::::::: :::::::::::::::::::::::::::::::::::
XP_006 WAADRQAALTKLRYSLRQYNIVGLHTNIDFLLNLSGHPEFEAGNVHTDFIPQHHKQLLLS
340 350 360 370 380 390
500 510 520 530 540 550
pF1KB5 RKAAAKESLCQAALGLILKEKAMTDTFTLQAHDQFSPFSSSSGRRLNISYTRNMTLKDGK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 RKAAAKESLCQAALGLILKEKAMTDTFTLQAHDQFSPFSSSSGRRLNISYTRNMTLKDGK
400 410 420 430 440 450
560 570 580 590 600 610
pF1KB5 NNVAIAVTYNHDGSYSMQIEDKTFQVLGNLYSEGDCTYLKCSVNGVASKAKLIILENTIY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 NNVAIAVTYNHDGSYSMQIEDKTFQVLGNLYSEGDCTYLKCSVNGVASKAKLIILENTIY
460 470 480 490 500 510
620 630 640 650 660 670
pF1KB5 LFSKEGSIEIDIPVPKYLSSVSSQETQGGPLAPMTGTIEKVFVKAGDKVKAGDSLMVMIA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LFSKEGSIEIDIPVPKYLSSVSSQETQGGPLAPMTGTIEKVFVKAGDKVKAGDSLMVMIA
520 530 540 550 560 570
680 690 700 710 720
pF1KB5 MKMEHTIKSPKDGTVKKVFYREGAQANRHTPLVEFEEEESDKRESE
::::::::::::::::::::::::::::::::::::::::::::::
XP_006 MKMEHTIKSPKDGTVKKVFYREGAQANRHTPLVEFEEEESDKRESE
580 590 600 610
>>NP_001280202 (OMIM: 210200,609010) methylcrotonoyl-CoA (608 aa)
initn: 3647 init1: 3647 opt: 3647 Z-score: 4141.6 bits: 776.7 E(85289): 0
Smith-Waterman score: 3647; 99.3% identity (99.6% similar) in 564 aa overlap (162-725:45-608)
140 150 160 170 180 190
pF1KB5 LSENMEFAELCKQEGIIFIGPPPSAIRDMGIKSTSKSIMAAAGVPVVEGYHGEDQSDQCL
..::::::::::::::::::::::::::::
NP_001 RQMKHIPSAPLPPSRATYLWRKSFKWPRPLLHSTSKSIMAAAGVPVVEGYHGEDQSDQCL
20 30 40 50 60 70
200 210 220 230 240 250
pF1KB5 KEHARRIGYPVMIKAVRGGGGKGMRIVRSEQEFQEQLESAWREAKKSFNDDAMLIEKFVD
:::::::::::::::::::::::::::::::::::::::: :::::::::::::::::::
NP_001 KEHARRIGYPVMIKAVRGGGGKGMRIVRSEQEFQEQLESARREAKKSFNDDAMLIEKFVD
80 90 100 110 120 130
260 270 280 290 300 310
pF1KB5 TPRHVEVQVFGDHHGNAVYLFERDCSVQRRHQKIIEEAPAPGIKSEVRKKLGEAAVRAAK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TPRHVEVQVFGDHHGNAVYLFERDCSVQRRHQKIIEEAPAPGIKSEVRKKLGEAAVRAAK
140 150 160 170 180 190
320 330 340 350 360 370
pF1KB5 AVNYVGAGTVEFIMDSKHNFCFMEMNTRLQVEHPVTEMITGTDLVEWQLRIAAGEKIPLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AVNYVGAGTVEFIMDSKHNFCFMEMNTRLQVEHPVTEMITGTDLVEWQLRIAAGEKIPLS
200 210 220 230 240 250
380 390 400 410 420 430
pF1KB5 QEEITLQGHAFEARIYAEDPSNNFMPVAGPLVHLSTPRADPSTRIETGVRQGDEVSVHYD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QEEITLQGHAFEARIYAEDPSNNFMPVAGPLVHLSTPRADPSTRIETGVRQGDEVSVHYD
260 270 280 290 300 310
440 450 460 470 480 490
pF1KB5 PMIAKLVVWAADRQAALTKLRYSLRQYNIVGLPTNIDFLLNLSGHPEFEAGNVHTDFIPQ
:::::::::::::::::::::::::::::::: :::::::::::::::::::::::::::
NP_001 PMIAKLVVWAADRQAALTKLRYSLRQYNIVGLHTNIDFLLNLSGHPEFEAGNVHTDFIPQ
320 330 340 350 360 370
500 510 520 530 540 550
pF1KB5 HHKQLLLSRKAAAKESLCQAALGLILKEKAMTDTFTLQAHDQFSPFSSSSGRRLNISYTR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HHKQLLLSRKAAAKESLCQAALGLILKEKAMTDTFTLQAHDQFSPFSSSSGRRLNISYTR
380 390 400 410 420 430
560 570 580 590 600 610
pF1KB5 NMTLKDGKNNVAIAVTYNHDGSYSMQIEDKTFQVLGNLYSEGDCTYLKCSVNGVASKAKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NMTLKDGKNNVAIAVTYNHDGSYSMQIEDKTFQVLGNLYSEGDCTYLKCSVNGVASKAKL
440 450 460 470 480 490
620 630 640 650 660 670
pF1KB5 IILENTIYLFSKEGSIEIDIPVPKYLSSVSSQETQGGPLAPMTGTIEKVFVKAGDKVKAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IILENTIYLFSKEGSIEIDIPVPKYLSSVSSQETQGGPLAPMTGTIEKVFVKAGDKVKAG
500 510 520 530 540 550
680 690 700 710 720
pF1KB5 DSLMVMIAMKMEHTIKSPKDGTVKKVFYREGAQANRHTPLVEFEEEESDKRESE
::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DSLMVMIAMKMEHTIKSPKDGTVKKVFYREGAQANRHTPLVEFEEEESDKRESE
560 570 580 590 600
>>XP_011511295 (OMIM: 210200,609010) PREDICTED: methylcr (472 aa)
initn: 3023 init1: 3023 opt: 3023 Z-score: 3434.8 bits: 645.5 E(85289): 1.4e-184
Smith-Waterman score: 3023; 99.4% identity (99.6% similar) in 463 aa overlap (1-463:1-463)
10 20 30 40 50 60
pF1KB5 MAAASAVSVLLVAAERNRWHRLPSLLLPPRTWVWRQRTMKYTTATGRNITKVLIANRGEI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MAAASAVSVLLVAAERNRWHRLPSLLLPPRTWVWRQRTMKYTTATGRNITKVLIANRGEI
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB5 ACRVMRTAKKLGVQTVAVYSEADRNSMHVDMADEAYSIGPAPSQQSYLSMEKIIQVAKTS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ACRVMRTAKKLGVQTVAVYSEADRNSMHVDMADEAYSIGPAPSQQSYLSMEKIIQVAKTS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB5 AAQAIHPGCGFLSENMEFAELCKQEGIIFIGPPPSAIRDMGIKSTSKSIMAAAGVPVVEG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AAQAIHPGCGFLSENMEFAELCKQEGIIFIGPPPSAIRDMGIKSTSKSIMAAAGVPVVEG
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB5 YHGEDQSDQCLKEHARRIGYPVMIKAVRGGGGKGMRIVRSEQEFQEQLESAWREAKKSFN
::::::::::::::::::::::::::::::::::::::::::::::::::: ::::::::
XP_011 YHGEDQSDQCLKEHARRIGYPVMIKAVRGGGGKGMRIVRSEQEFQEQLESARREAKKSFN
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB5 DDAMLIEKFVDTPRHVEVQVFGDHHGNAVYLFERDCSVQRRHQKIIEEAPAPGIKSEVRK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DDAMLIEKFVDTPRHVEVQVFGDHHGNAVYLFERDCSVQRRHQKIIEEAPAPGIKSEVRK
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB5 KLGEAAVRAAKAVNYVGAGTVEFIMDSKHNFCFMEMNTRLQVEHPVTEMITGTDLVEWQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KLGEAAVRAAKAVNYVGAGTVEFIMDSKHNFCFMEMNTRLQVEHPVTEMITGTDLVEWQL
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB5 RIAAGEKIPLSQEEITLQGHAFEARIYAEDPSNNFMPVAGPLVHLSTPRADPSTRIETGV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RIAAGEKIPLSQEEITLQGHAFEARIYAEDPSNNFMPVAGPLVHLSTPRADPSTRIETGV
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB5 RQGDEVSVHYDPMIAKLVVWAADRQAALTKLRYSLRQYNIVGLPTNIDFLLNLSGHPEFE
:::::::::::::::::::::::::::::::::::::::: .:
XP_011 RQGDEVSVHYDPMIAKLVVWAADRQAALTKLRYSLRQYNINSLHFRLAVEED
430 440 450 460 470
490 500 510 520 530 540
pF1KB5 AGNVHTDFIPQHHKQLLLSRKAAAKESLCQAALGLILKEKAMTDTFTLQAHDQFSPFSSS
>>NP_001121164 (OMIM: 232000,606054) propionyl-CoA carbo (702 aa)
initn: 1632 init1: 1263 opt: 1603 Z-score: 1819.9 bits: 347.3 E(85289): 1.3e-94
Smith-Waterman score: 1610; 39.5% identity (68.1% similar) in 722 aa overlap (10-715:11-702)
10 20 30 40 50
pF1KB5 MAAASAVSVLLVAAERNRWHRLPSLLLPPRTWVWRQRTMKYTTATGRNITKVLIANRGE
:..:..:.:: ::. : .. . : ... :.:.:::::
NP_001 MAGFWVGTAPLVAAGRRGRW--------PPQ-----QLMLSAALRTLKTFDKILVANRGE
10 20 30 40
60 70 80 90 100 110
pF1KB5 IACRVMRTAKKLGVQTVAVYSEADRNSMHVDMADEAYSIGPAPSQQSYLSMEKIIQVAKT
:::::.:: ::.:..:::..:..: .:.:: ::::: .::::...:::.:. :... :
NP_001 IACRVIRTCKKMGIKTVAIHSDVDASSVHVKMADEAVCVGPAPTSKSYLNMDAIMEAIKK
50 60 70 80 90 100
120 130 140 150 160 170
pF1KB5 SAAQAIHPGCGFLSENMEFAELCKQEGIIFIGPPPSAIRDMGIKSTSKSIMAAAGVPVVE
. :::.::: :::::: :::. : ..:::: ::. :: : :: . : : ..
NP_001 TRAQAVHPGYGFLSENKEFARCLAAEDVVFIGPDTHAIQAMGDKIESKLLAKKAEVNTIP
110 120 130 140 150 160
180 190 200 210 220 230
pF1KB5 GYHGEDQSDQCLKEHARRIGYPVMIKAVRGGGGKGMRIVRSEQEFQEQLESAWREAKKSF
:. : .. . . ::.::::::::: :::::::::. ...: .. .. . .:: .::
NP_001 GFDGVVKDAEEAVRIAREIGYPVMIKASAGGGGKGMRIAWDDEETRDGFRLSSQEAASSF
170 180 190 200 210 220
240 250 260 270 280 290
pF1KB5 NDDAMLIEKFVDTPRHVEVQVFGDHHGNAVYLFERDCSVQRRHQKIIEEAPAPGIKSEVR
.:: .:::::.:.:::.:.::.::.::::..: ::.::.:::.::..::::. . .:.:
NP_001 GDDRLLIEKFIDNPRHIEIQVLGDKHGNALWLNERECSIQRRNQKVVEEAPSIFLDAETR
230 240 250 260 270 280
300 310 320 330 340 350
pF1KB5 KKLGEAAVRAAKAVNYVGAGTVEFIMDSKHNFCFMEMNTRLQVEHPVTEMITGTDLVEWQ
. .:: :: :.::.: .::::::..:::.:: :.:::::::::::::: ::: :::. .
NP_001 RAMGEQAVALARAVKYSSAGTVEFLVDSKKNFYFLEMNTRLQVEHPVTECITGLDLVQEM
290 300 310 320 330 340
360 370 380 390 400 410
pF1KB5 LRIAAGEKIPLSQEEITLQGHAFEARIYAEDPSNNF-MPVAGPLVHLSTPRADPSTRIET
.:.: : . .: .: ..: : : :.::::: ..: .: : : . . : :..:...
NP_001 IRVAKGYPLRHKQADIRINGWAVECRVYAEDPYKSFGLPSIGRLSQYQEPLHLPGVRVDS
350 360 370 380 390 400
420 430 440 450 460 470
pF1KB5 GVRQGDEVSVHYDPMIAKLVVWAADRQAALTKLRYSLRQYNIVGLPTNIDFLLNLSGHPE
:.. :...:..:::::.::.....:: :: .. .: .: : :. :: .: .. . .
NP_001 GIQPGSDISIYYDPMISKLITYGSDRTEALKRMADALDNYVIRGVTHNIALLREVIINSR
410 420 430 440 450 460
480 490 500 510 520 530
pF1KB5 FEAGNVHTDFI----PQHHKQLLLSRKAAAKESLCQAALGLILKEKAMTDTFTLQAHDQF
: :.. : :. :. : .:.. . :..: : .:.. .: :.:. .:
NP_001 FVKGDISTKFLSDVYPDGFKGHMLTK--SEKNQLLAIASSLFV-------AFQLRAQ-HF
470 480 490 500 510
540 550 560 570 580 590
pF1KB5 SPFSSSSGRRLNIS-YTRNMTLKDGKNNVAIAVTYNHDGSYSMQIEDKTFQVLG--NLYS
. : . .:. . .. :.: .: .:. :. . .:.... . ..: . :: :
NP_001 QENSRMPVIKPDIANWELSVKLHD---KVHTVVASNNGSVFSVEVDGSKLNVTSTWNLAS
520 530 540 550 560 570
600 610 620 630 640
pF1KB5 EGDCTYLKCSVNGVASKAKLIILEN----TIYLFSKEGSIEI----DIPVPKYLSSVSSQ
:. ::.:. .. . : .: ... ...: . :.. ..
NP_001 P----LLSVSVDGTQRTVQCLSREAGGNMSIQFLGTVYKVNILTRLAAELNKFMLEKVTE
580 590 600 610 620 630
650 660 670 680 690 700
pF1KB5 ETQGGPLAPMTGTIEKVFVKAGDKVKAGDSLMVMIAMKMEHTIKSPKDGTVKKVFYREGA
.:.. .:: :.. : :: :: : :. . :. ::::.... . : ::::.: . :
NP_001 DTSSVLRSPMPGVVVAVSVKPGDAVAEGQEICVIEAMKMQNSMTAGKTGTVKSVHCQAGD
640 650 660 670 680 690
710 720
pF1KB5 QANRHTPLVEFEEEESDKRESE
... :::.:
NP_001 TVGEGDLLVELE
700
>>XP_016876098 (OMIM: 232000,606054) PREDICTED: propiony (695 aa)
initn: 1631 init1: 1262 opt: 1592 Z-score: 1807.4 bits: 345.0 E(85289): 6.2e-94
Smith-Waterman score: 1593; 40.3% identity (69.2% similar) in 685 aa overlap (47-715:28-695)
20 30 40 50 60 70
pF1KB5 NRWHRLPSLLLPPRTWVWRQRTMKYTTATGRNITKVLIANRGEIACRVMRTAKKLGVQTV
... :.:.::::::::::.:: ::.:..::
XP_016 MEHVLYYSRQCLMVSRNLGSVGYDPNEKTFDKILVANRGEIACRVIRTCKKMGIKTV
10 20 30 40 50
80 90 100 110 120 130
pF1KB5 AVYSEADRNSMHVDMADEAYSIGPAPSQQSYLSMEKIIQVAKTSAAQAIHPGCGFLSENM
:..:..: .:.:: ::::: .::::...:::.:. :... : . :::.::: ::::::
XP_016 AIHSDVDASSVHVKMADEAVCVGPAPTSKSYLNMDAIMEAIKKTRAQAVHPGYGFLSENK
60 70 80 90 100 110
140 150 160 170 180 190
pF1KB5 EFAELCKQEGIIFIGPPPSAIRDMGIKSTSKSIMAAAGVPVVEGYHGEDQSDQCLKEHAR
:::. : ..:::: ::. :: : :: . : : .. :. : .. . . ::
XP_016 EFARCLAAEDVVFIGPDTHAIQAMGDKIESKLLAKKAEVNTIPGFDGVVKDAEEAVRIAR
120 130 140 150 160 170
200 210 220 230 240 250
pF1KB5 RIGYPVMIKAVRGGGGKGMRIVRSEQEFQEQLESAWREAKKSFNDDAMLIEKFVDTPRHV
.::::::::: :::::::::. ...: .. .. . .:: .::.:: .:::::.:.:::.
XP_016 EIGYPVMIKASAGGGGKGMRIAWDDEETRDGFRLSSQEAASSFGDDRLLIEKFIDNPRHI
180 190 200 210 220 230
260 270 280 290 300 310
pF1KB5 EVQVFGDHHGNAVYLFERDCSVQRRHQKIIEEAPAPGIKSEVRKKLGEAAVRAAKAVNYV
:.::.::.::::..: ::.::.:::.::..::::. . .:.:. .:: :: :.::.:
XP_016 EIQVLGDKHGNALWLNERECSIQRRNQKVVEEAPSIFLDAETRRAMGEQAVALARAVKYS
240 250 260 270 280 290
320 330 340 350 360 370
pF1KB5 GAGTVEFIMDSKHNFCFMEMNTRLQVEHPVTEMITGTDLVEWQLRIAAGEKIPLSQEEIT
.::::::..:::.:: :.:::::::::::::: ::: :::. ..:.: : . .: .:
XP_016 SAGTVEFLVDSKKNFYFLEMNTRLQVEHPVTECITGLDLVQEMIRVAKGYPLRHKQADIR
300 310 320 330 340 350
380 390 400 410 420 430
pF1KB5 LQGHAFEARIYAEDPSNNF-MPVAGPLVHLSTPRADPSTRIETGVRQGDEVSVHYDPMIA
..: : : :.::::: ..: .: : : . . : :..:...:.. :...:..:::::.
XP_016 INGWAVECRVYAEDPYKSFGLPSIGRLSQYQEPLHLPGVRVDSGIQPGSDISIYYDPMIS
360 370 380 390 400 410
440 450 460 470 480 490
pF1KB5 KLVVWAADRQAALTKLRYSLRQYNIVGLPTNIDFLLNLSGHPEFEAGNVHTDFI----PQ
::.....:: :: .. .: .: : :. :: .: .. . .: :.. : :. :.
XP_016 KLITYGSDRTEALKRMADALDNYVIRGVTHNIALLREVIINSRFVKGDISTKFLSDVYPD
420 430 440 450 460 470
500 510 520 530 540 550
pF1KB5 HHKQLLLSRKAAAKESLCQAALGLILKEKAMTDTFTLQAHDQFSPFSSSSGRRLNIS-YT
: .:.. . :..: : .:.. .: :.:. .:. : . .:. .
XP_016 GFKGHMLTK--SEKNQLLAIASSLFV-------AFQLRAQ-HFQENSRMPVIKPDIANWE
480 490 500 510 520
560 570 580 590 600
pF1KB5 RNMTLKDGKNNVAIAVTYNHDGSYSMQIEDKTFQVLG--NLYSEGDCTYLKCSVNGVASK
.. :.: .: .:. :. . .:.... . ..: . :: : :. ::.:.
XP_016 LSVKLHD---KVHTVVASNNGSVFSVEVDGSKLNVTSTWNLASP----LLSVSVDGTQRT
530 540 550 560 570 580
610 620 630 640 650 660
pF1KB5 AKLIILEN----TIYLFSKEGSIEI----DIPVPKYLSSVSSQETQGGPLAPMTGTIEKV
.. . : .: ... ...: . :.. ...:.. .:: :.. :
XP_016 VQCLSREAGGNMSIQFLGTVYKVNILTRLAAELNKFMLEKVTEDTSSVLRSPMPGVVVAV
590 600 610 620 630 640
670 680 690 700 710 720
pF1KB5 FVKAGDKVKAGDSLMVMIAMKMEHTIKSPKDGTVKKVFYREGAQANRHTPLVEFEEEESD
:: :: : :. . :. ::::.... . : ::::.: . : ... :::.:
XP_016 SVKPGDAVAEGQEICVIEAMKMQNSMTAGKTGTVKSVHCQAGDTVGEGDLLVELE
650 660 670 680 690
pF1KB5 KRESE
>>NP_000273 (OMIM: 232000,606054) propionyl-CoA carboxyl (728 aa)
initn: 1631 init1: 1262 opt: 1592 Z-score: 1807.1 bits: 345.0 E(85289): 6.4e-94
Smith-Waterman score: 1593; 40.3% identity (69.2% similar) in 685 aa overlap (47-715:61-728)
20 30 40 50 60 70
pF1KB5 NRWHRLPSLLLPPRTWVWRQRTMKYTTATGRNITKVLIANRGEIACRVMRTAKKLGVQTV
... :.:.::::::::::.:: ::.:..::
NP_000 LRTLKHVLYYSRQCLMVSRNLGSVGYDPNEKTFDKILVANRGEIACRVIRTCKKMGIKTV
40 50 60 70 80 90
80 90 100 110 120 130
pF1KB5 AVYSEADRNSMHVDMADEAYSIGPAPSQQSYLSMEKIIQVAKTSAAQAIHPGCGFLSENM
:..:..: .:.:: ::::: .::::...:::.:. :... : . :::.::: ::::::
NP_000 AIHSDVDASSVHVKMADEAVCVGPAPTSKSYLNMDAIMEAIKKTRAQAVHPGYGFLSENK
100 110 120 130 140 150
140 150 160 170 180 190
pF1KB5 EFAELCKQEGIIFIGPPPSAIRDMGIKSTSKSIMAAAGVPVVEGYHGEDQSDQCLKEHAR
:::. : ..:::: ::. :: : :: . : : .. :. : .. . . ::
NP_000 EFARCLAAEDVVFIGPDTHAIQAMGDKIESKLLAKKAEVNTIPGFDGVVKDAEEAVRIAR
160 170 180 190 200 210
200 210 220 230 240 250
pF1KB5 RIGYPVMIKAVRGGGGKGMRIVRSEQEFQEQLESAWREAKKSFNDDAMLIEKFVDTPRHV
.::::::::: :::::::::. ...: .. .. . .:: .::.:: .:::::.:.:::.
NP_000 EIGYPVMIKASAGGGGKGMRIAWDDEETRDGFRLSSQEAASSFGDDRLLIEKFIDNPRHI
220 230 240 250 260 270
260 270 280 290 300 310
pF1KB5 EVQVFGDHHGNAVYLFERDCSVQRRHQKIIEEAPAPGIKSEVRKKLGEAAVRAAKAVNYV
:.::.::.::::..: ::.::.:::.::..::::. . .:.:. .:: :: :.::.:
NP_000 EIQVLGDKHGNALWLNERECSIQRRNQKVVEEAPSIFLDAETRRAMGEQAVALARAVKYS
280 290 300 310 320 330
320 330 340 350 360 370
pF1KB5 GAGTVEFIMDSKHNFCFMEMNTRLQVEHPVTEMITGTDLVEWQLRIAAGEKIPLSQEEIT
.::::::..:::.:: :.:::::::::::::: ::: :::. ..:.: : . .: .:
NP_000 SAGTVEFLVDSKKNFYFLEMNTRLQVEHPVTECITGLDLVQEMIRVAKGYPLRHKQADIR
340 350 360 370 380 390
380 390 400 410 420 430
pF1KB5 LQGHAFEARIYAEDPSNNF-MPVAGPLVHLSTPRADPSTRIETGVRQGDEVSVHYDPMIA
..: : : :.::::: ..: .: : : . . : :..:...:.. :...:..:::::.
NP_000 INGWAVECRVYAEDPYKSFGLPSIGRLSQYQEPLHLPGVRVDSGIQPGSDISIYYDPMIS
400 410 420 430 440 450
440 450 460 470 480 490
pF1KB5 KLVVWAADRQAALTKLRYSLRQYNIVGLPTNIDFLLNLSGHPEFEAGNVHTDFI----PQ
::.....:: :: .. .: .: : :. :: .: .. . .: :.. : :. :.
NP_000 KLITYGSDRTEALKRMADALDNYVIRGVTHNIALLREVIINSRFVKGDISTKFLSDVYPD
460 470 480 490 500 510
500 510 520 530 540 550
pF1KB5 HHKQLLLSRKAAAKESLCQAALGLILKEKAMTDTFTLQAHDQFSPFSSSSGRRLNIS-YT
: .:.. . :..: : .:.. .: :.:. .:. : . .:. .
NP_000 GFKGHMLTK--SEKNQLLAIASSLFV-------AFQLRAQ-HFQENSRMPVIKPDIANWE
520 530 540 550 560
560 570 580 590 600
pF1KB5 RNMTLKDGKNNVAIAVTYNHDGSYSMQIEDKTFQVLG--NLYSEGDCTYLKCSVNGVASK
.. :.: .: .:. :. . .:.... . ..: . :: : :. ::.:.
NP_000 LSVKLHD---KVHTVVASNNGSVFSVEVDGSKLNVTSTWNLASP----LLSVSVDGTQRT
570 580 590 600 610
610 620 630 640 650 660
pF1KB5 AKLIILEN----TIYLFSKEGSIEI----DIPVPKYLSSVSSQETQGGPLAPMTGTIEKV
.. . : .: ... ...: . :.. ...:.. .:: :.. :
NP_000 VQCLSREAGGNMSIQFLGTVYKVNILTRLAAELNKFMLEKVTEDTSSVLRSPMPGVVVAV
620 630 640 650 660 670
670 680 690 700 710 720
pF1KB5 FVKAGDKVKAGDSLMVMIAMKMEHTIKSPKDGTVKKVFYREGAQANRHTPLVEFEEEESD
:: :: : :. . :. ::::.... . : ::::.: . : ... :::.:
NP_000 SVKPGDAVAEGQEICVIEAMKMQNSMTAGKTGTVKSVHCQAGDTVGEGDLLVELE
680 690 700 710 720
pF1KB5 KRESE
725 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sat Nov 5 22:11:24 2016 done: Sat Nov 5 22:11:26 2016
Total Scan time: 10.460 Total Display time: 0.190
Function used was FASTA [36.3.4 Apr, 2011]