Result of FASTA (omim) for
pFN21AE0094
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE0094, 535 aa
1>>>pF1KE0094 535 - 535 aa - 535 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.2175+/-0.000458; mu= 20.2449+/- 0.028
mean_var=85.9934+/-17.267, 0's: 0 Z-trim(111.6): 90 B-trim: 0 in 0/49
Lambda= 0.138306
statistics sampled from 20130 (20221) to 20130 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.599), E-opt: 0.2 (0.237), width: 16
Scan time: 8.830
The best scores are: opt bits E(85289)
NP_055415 (OMIM: 605891) EH domain-containing prot ( 535) 3558 720.4 3.4e-207
XP_011543041 (OMIM: 605888) PREDICTED: EH domain-c ( 534) 3188 646.6 5.6e-185
NP_006786 (OMIM: 605888) EH domain-containing prot ( 534) 3188 646.6 5.6e-185
NP_001269373 (OMIM: 605888) EH domain-containing p ( 534) 3188 646.6 5.6e-185
NP_001269374 (OMIM: 605888) EH domain-containing p ( 548) 3188 646.6 5.7e-185
NP_644670 (OMIM: 605892) EH domain-containing prot ( 541) 2748 558.8 1.5e-158
NP_055416 (OMIM: 605890) EH domain-containing prot ( 543) 2608 530.8 3.9e-150
XP_016877589 (OMIM: 605892) PREDICTED: EH domain-c ( 453) 2330 475.3 1.7e-133
XP_011531108 (OMIM: 605891) PREDICTED: EH domain-c ( 322) 2131 435.5 1.2e-121
NP_001310597 (OMIM: 604992) sarcalumenin isoform 2 ( 431) 755 161.0 6.6e-39
XP_016879017 (OMIM: 604992) PREDICTED: sarcalumeni ( 431) 755 161.0 6.6e-39
NP_001310596 (OMIM: 604992) sarcalumenin isoform 2 ( 431) 755 161.0 6.6e-39
XP_016879018 (OMIM: 604992) PREDICTED: sarcalumeni ( 431) 755 161.0 6.6e-39
NP_001092284 (OMIM: 604992) sarcalumenin isoform 1 ( 473) 755 161.1 7.1e-39
XP_016879016 (OMIM: 604992) PREDICTED: sarcalumeni ( 857) 755 161.3 1.1e-38
XP_016856106 (OMIM: 600051) PREDICTED: epidermal g ( 828) 332 76.9 2.7e-13
XP_016856105 (OMIM: 600051) PREDICTED: epidermal g ( 865) 332 76.9 2.8e-13
NP_001972 (OMIM: 600051) epidermal growth factor r ( 896) 332 76.9 2.9e-13
XP_016856104 (OMIM: 600051) PREDICTED: epidermal g ( 933) 332 76.9 3e-13
NP_001245305 (OMIM: 616826) epidermal growth facto ( 601) 327 75.8 4.3e-13
XP_016882581 (OMIM: 616826) PREDICTED: epidermal g ( 750) 327 75.8 5.1e-13
NP_001245304 (OMIM: 616826) epidermal growth facto ( 754) 327 75.8 5.1e-13
XP_016882580 (OMIM: 616826) PREDICTED: epidermal g ( 796) 327 75.9 5.3e-13
XP_016882579 (OMIM: 616826) PREDICTED: epidermal g ( 797) 327 75.9 5.3e-13
XP_016882578 (OMIM: 616826) PREDICTED: epidermal g ( 845) 327 75.9 5.5e-13
NP_067058 (OMIM: 616826) epidermal growth factor r ( 864) 327 75.9 5.6e-13
XP_016882577 (OMIM: 616826) PREDICTED: epidermal g ( 874) 327 75.9 5.7e-13
NP_001245303 (OMIM: 616826) epidermal growth facto ( 910) 327 75.9 5.8e-13
XP_016882576 (OMIM: 616826) PREDICTED: epidermal g ( 915) 327 75.9 5.8e-13
XP_016882575 (OMIM: 616826) PREDICTED: epidermal g ( 926) 327 75.9 5.9e-13
XP_011527995 (OMIM: 602442) PREDICTED: intersectin (1020) 257 62.0 1e-08
XP_016883930 (OMIM: 602442) PREDICTED: intersectin (1025) 257 62.0 1e-08
XP_011527994 (OMIM: 602442) PREDICTED: intersectin (1107) 257 62.0 1.1e-08
XP_016883929 (OMIM: 602442) PREDICTED: intersectin (1112) 257 62.0 1.1e-08
NP_001317940 (OMIM: 602442) intersectin-1 isoform (1144) 257 62.0 1.1e-08
NP_001317937 (OMIM: 602442) intersectin-1 isoform (1149) 257 62.0 1.1e-08
NP_001317941 (OMIM: 602442) intersectin-1 isoform (1178) 257 62.1 1.1e-08
XP_016883927 (OMIM: 602442) PREDICTED: intersectin (1183) 257 62.1 1.1e-08
NP_001317938 (OMIM: 602442) intersectin-1 isoform (1215) 257 62.1 1.1e-08
NP_001001132 (OMIM: 602442) intersectin-1 isoform (1220) 257 62.1 1.2e-08
XP_016883925 (OMIM: 602442) PREDICTED: intersectin (1608) 257 62.2 1.4e-08
XP_016883924 (OMIM: 602442) PREDICTED: intersectin (1613) 257 62.2 1.4e-08
XP_016883923 (OMIM: 602442) PREDICTED: intersectin (1645) 257 62.2 1.4e-08
XP_016883922 (OMIM: 602442) PREDICTED: intersectin (1650) 257 62.2 1.4e-08
XP_016883921 (OMIM: 602442) PREDICTED: intersectin (1660) 257 62.2 1.4e-08
XP_016883920 (OMIM: 602442) PREDICTED: intersectin (1665) 257 62.2 1.4e-08
XP_016883919 (OMIM: 602442) PREDICTED: intersectin (1679) 257 62.2 1.5e-08
XP_016883918 (OMIM: 602442) PREDICTED: intersectin (1684) 257 62.2 1.5e-08
NP_001317939 (OMIM: 602442) intersectin-1 isoform (1716) 257 62.2 1.5e-08
XP_016883917 (OMIM: 602442) PREDICTED: intersectin (1721) 257 62.2 1.5e-08
>>NP_055415 (OMIM: 605891) EH domain-containing protein (535 aa)
initn: 3558 init1: 3558 opt: 3558 Z-score: 3840.9 bits: 720.4 E(85289): 3.4e-207
Smith-Waterman score: 3558; 100.0% identity (100.0% similar) in 535 aa overlap (1-535:1-535)
10 20 30 40 50 60
pF1KE0 MFSWLGTDDRRRKDPEVFQTVSEGLKKLYKSKLLPLEEHYRFHEFHSPALEDADFDNKPM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 MFSWLGTDDRRRKDPEVFQTVSEGLKKLYKSKLLPLEEHYRFHEFHSPALEDADFDNKPM
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 VLLVGQYSTGKTTFIRYLLEQDFPGMRIGPEPTTDSFIAVMQGDMEGIIPGNALVVDPKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 VLLVGQYSTGKTTFIRYLLEQDFPGMRIGPEPTTDSFIAVMQGDMEGIIPGNALVVDPKK
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE0 PFRKLNAFGNAFLNRFVCAQLPNPVLESISVIDTPGILSGEKQRISRGYDFAAVLEWFAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 PFRKLNAFGNAFLNRFVCAQLPNPVLESISVIDTPGILSGEKQRISRGYDFAAVLEWFAE
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE0 RVDRIILLFDAHKLDISDEFSEVIKALKNHEDKMRVVLNKADQIETQQLMRVYGALMWSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 RVDRIILLFDAHKLDISDEFSEVIKALKNHEDKMRVVLNKADQIETQQLMRVYGALMWSL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE0 GKIVNTPEVIRVYIGSFWSHPLLIPDNRKLFEAEEQDLFRDIQSLPRNAALRKLNDLIKR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 GKIVNTPEVIRVYIGSFWSHPLLIPDNRKLFEAEEQDLFRDIQSLPRNAALRKLNDLIKR
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE0 ARLAKVHAYIISSLKKEMPSVFGKDNKKKELVNNLAEIYGRIEREHQISPGDFPNLKRMQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 ARLAKVHAYIISSLKKEMPSVFGKDNKKKELVNNLAEIYGRIEREHQISPGDFPNLKRMQ
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE0 DQLQAQDFSKFQPLKSKLLEVVDDMLAHDIAQLMVLVRQEESQRPIQMVKGGAFEGTLHG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 DQLQAQDFSKFQPLKSKLLEVVDDMLAHDIAQLMVLVRQEESQRPIQMVKGGAFEGTLHG
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE0 PFGHGYGEGAGEGIDDAEWVVARDKPMYDEIFYTLSPVDGKITGANAKKEMVRSKLPNSV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 PFGHGYGEGAGEGIDDAEWVVARDKPMYDEIFYTLSPVDGKITGANAKKEMVRSKLPNSV
430 440 450 460 470 480
490 500 510 520 530
pF1KE0 LGKIWKLADIDKDGMLDDDEFALANHLIKVKLEGHELPNELPAHLLPPSKRKVAE
:::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 LGKIWKLADIDKDGMLDDDEFALANHLIKVKLEGHELPNELPAHLLPPSKRKVAE
490 500 510 520 530
>>XP_011543041 (OMIM: 605888) PREDICTED: EH domain-conta (534 aa)
initn: 3220 init1: 3188 opt: 3188 Z-score: 3441.9 bits: 646.6 E(85289): 5.6e-185
Smith-Waterman score: 3188; 87.0% identity (97.2% similar) in 532 aa overlap (1-532:1-532)
10 20 30 40 50 60
pF1KE0 MFSWLGTDDRRRKDPEVFQTVSEGLKKLYKSKLLPLEEHYRFHEFHSPALEDADFDNKPM
::::.. : ::.:.::.::::.:::..:: .:::::::::::::::::::::::::::::
XP_011 MFSWVSKDARRKKEPELFQTVAEGLRQLYAQKLLPLEEHYRFHEFHSPALEDADFDNKPM
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 VLLVGQYSTGKTTFIRYLLEQDFPGMRIGPEPTTDSFIAVMQGDMEGIIPGNALVVDPKK
::::::::::::::::.:.::::::::::::::::::::::.: ::..:::::::::..
XP_011 VLLVGQYSTGKTTFIRHLIEQDFPGMRIGPEPTTDSFIAVMHGPTEGVVPGNALVVDPRR
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE0 PFRKLNAFGNAFLNRFVCAQLPNPVLESISVIDTPGILSGEKQRISRGYDFAAVLEWFAE
::::::::::::::::.:::::::::.:::.:::::::::::::::::::::::::::::
XP_011 PFRKLNAFGNAFLNRFMCAQLPNPVLDSISIIDTPGILSGEKQRISRGYDFAAVLEWFAE
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE0 RVDRIILLFDAHKLDISDEFSEVIKALKNHEDKMRVVLNKADQIETQQLMRVYGALMWSL
:::::::::::::::::::::::::::::::::.::::::::::::::::::::::::::
XP_011 RVDRIILLFDAHKLDISDEFSEVIKALKNHEDKIRVVLNKADQIETQQLMRVYGALMWSL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE0 GKIVNTPEVIRVYIGSFWSHPLLIPDNRKLFEAEEQDLFRDIQSLPRNAALRKLNDLIKR
:::.:::::.:::::::::::::::::::::::::::::.::::::::::::::::::::
XP_011 GKIINTPEVVRVYIGSFWSHPLLIPDNRKLFEAEEQDLFKDIQSLPRNAALRKLNDLIKR
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE0 ARLAKVHAYIISSLKKEMPSVFGKDNKKKELVNNLAEIYGRIEREHQISPGDFPNLKRMQ
:::::::::::::::::::.::::..:::::::::.::: .:::::::::::::.:..::
XP_011 ARLAKVHAYIISSLKKEMPNVFGKESKKKELVNNLGEIYQKIEREHQISPGDFPSLRKMQ
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE0 DQLQAQDFSKFQPLKSKLLEVVDDMLAHDIAQLMVLVRQEESQRPIQMVKGGAFEGTLHG
. ::.::::::: :: :::..::::::.:::.:::.:::::: : :.::::::.::..:
XP_011 ELLQTQDFSKFQALKPKLLDTVDDMLANDIARLMVMVRQEESLMPSQVVKGGAFDGTMNG
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE0 PFGHGYGEGAGEGIDDAEWVVARDKPMYDEIFYTLSPVDGKITGANAKKEMVRSKLPNSV
::::::::::::::::.::::..::: :::::::::::.:::::::::::::.:::::.:
XP_011 PFGHGYGEGAGEGIDDVEWVVGKDKPTYDEIFYTLSPVNGKITGANAKKEMVKSKLPNTV
430 440 450 460 470 480
490 500 510 520 530
pF1KE0 LGKIWKLADIDKDGMLDDDEFALANHLIKVKLEGHELPNELPAHLLPPSKRKVAE
:::::::::.::::.:::.::::::::::::::::::: .:: ::.:::::.
XP_011 LGKIWKLADVDKDGLLDDEEFALANHLIKVKLEGHELPADLPPHLVPPSKRRHE
490 500 510 520 530
>>NP_006786 (OMIM: 605888) EH domain-containing protein (534 aa)
initn: 3220 init1: 3188 opt: 3188 Z-score: 3441.9 bits: 646.6 E(85289): 5.6e-185
Smith-Waterman score: 3188; 87.0% identity (97.2% similar) in 532 aa overlap (1-532:1-532)
10 20 30 40 50 60
pF1KE0 MFSWLGTDDRRRKDPEVFQTVSEGLKKLYKSKLLPLEEHYRFHEFHSPALEDADFDNKPM
::::.. : ::.:.::.::::.:::..:: .:::::::::::::::::::::::::::::
NP_006 MFSWVSKDARRKKEPELFQTVAEGLRQLYAQKLLPLEEHYRFHEFHSPALEDADFDNKPM
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 VLLVGQYSTGKTTFIRYLLEQDFPGMRIGPEPTTDSFIAVMQGDMEGIIPGNALVVDPKK
::::::::::::::::.:.::::::::::::::::::::::.: ::..:::::::::..
NP_006 VLLVGQYSTGKTTFIRHLIEQDFPGMRIGPEPTTDSFIAVMHGPTEGVVPGNALVVDPRR
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE0 PFRKLNAFGNAFLNRFVCAQLPNPVLESISVIDTPGILSGEKQRISRGYDFAAVLEWFAE
::::::::::::::::.:::::::::.:::.:::::::::::::::::::::::::::::
NP_006 PFRKLNAFGNAFLNRFMCAQLPNPVLDSISIIDTPGILSGEKQRISRGYDFAAVLEWFAE
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE0 RVDRIILLFDAHKLDISDEFSEVIKALKNHEDKMRVVLNKADQIETQQLMRVYGALMWSL
:::::::::::::::::::::::::::::::::.::::::::::::::::::::::::::
NP_006 RVDRIILLFDAHKLDISDEFSEVIKALKNHEDKIRVVLNKADQIETQQLMRVYGALMWSL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE0 GKIVNTPEVIRVYIGSFWSHPLLIPDNRKLFEAEEQDLFRDIQSLPRNAALRKLNDLIKR
:::.:::::.:::::::::::::::::::::::::::::.::::::::::::::::::::
NP_006 GKIINTPEVVRVYIGSFWSHPLLIPDNRKLFEAEEQDLFKDIQSLPRNAALRKLNDLIKR
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE0 ARLAKVHAYIISSLKKEMPSVFGKDNKKKELVNNLAEIYGRIEREHQISPGDFPNLKRMQ
:::::::::::::::::::.::::..:::::::::.::: .:::::::::::::.:..::
NP_006 ARLAKVHAYIISSLKKEMPNVFGKESKKKELVNNLGEIYQKIEREHQISPGDFPSLRKMQ
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE0 DQLQAQDFSKFQPLKSKLLEVVDDMLAHDIAQLMVLVRQEESQRPIQMVKGGAFEGTLHG
. ::.::::::: :: :::..::::::.:::.:::.:::::: : :.::::::.::..:
NP_006 ELLQTQDFSKFQALKPKLLDTVDDMLANDIARLMVMVRQEESLMPSQVVKGGAFDGTMNG
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE0 PFGHGYGEGAGEGIDDAEWVVARDKPMYDEIFYTLSPVDGKITGANAKKEMVRSKLPNSV
::::::::::::::::.::::..::: :::::::::::.:::::::::::::.:::::.:
NP_006 PFGHGYGEGAGEGIDDVEWVVGKDKPTYDEIFYTLSPVNGKITGANAKKEMVKSKLPNTV
430 440 450 460 470 480
490 500 510 520 530
pF1KE0 LGKIWKLADIDKDGMLDDDEFALANHLIKVKLEGHELPNELPAHLLPPSKRKVAE
:::::::::.::::.:::.::::::::::::::::::: .:: ::.:::::.
NP_006 LGKIWKLADVDKDGLLDDEEFALANHLIKVKLEGHELPADLPPHLVPPSKRRHE
490 500 510 520 530
>>NP_001269373 (OMIM: 605888) EH domain-containing prote (534 aa)
initn: 3220 init1: 3188 opt: 3188 Z-score: 3441.9 bits: 646.6 E(85289): 5.6e-185
Smith-Waterman score: 3188; 87.0% identity (97.2% similar) in 532 aa overlap (1-532:1-532)
10 20 30 40 50 60
pF1KE0 MFSWLGTDDRRRKDPEVFQTVSEGLKKLYKSKLLPLEEHYRFHEFHSPALEDADFDNKPM
::::.. : ::.:.::.::::.:::..:: .:::::::::::::::::::::::::::::
NP_001 MFSWVSKDARRKKEPELFQTVAEGLRQLYAQKLLPLEEHYRFHEFHSPALEDADFDNKPM
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 VLLVGQYSTGKTTFIRYLLEQDFPGMRIGPEPTTDSFIAVMQGDMEGIIPGNALVVDPKK
::::::::::::::::.:.::::::::::::::::::::::.: ::..:::::::::..
NP_001 VLLVGQYSTGKTTFIRHLIEQDFPGMRIGPEPTTDSFIAVMHGPTEGVVPGNALVVDPRR
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE0 PFRKLNAFGNAFLNRFVCAQLPNPVLESISVIDTPGILSGEKQRISRGYDFAAVLEWFAE
::::::::::::::::.:::::::::.:::.:::::::::::::::::::::::::::::
NP_001 PFRKLNAFGNAFLNRFMCAQLPNPVLDSISIIDTPGILSGEKQRISRGYDFAAVLEWFAE
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE0 RVDRIILLFDAHKLDISDEFSEVIKALKNHEDKMRVVLNKADQIETQQLMRVYGALMWSL
:::::::::::::::::::::::::::::::::.::::::::::::::::::::::::::
NP_001 RVDRIILLFDAHKLDISDEFSEVIKALKNHEDKIRVVLNKADQIETQQLMRVYGALMWSL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE0 GKIVNTPEVIRVYIGSFWSHPLLIPDNRKLFEAEEQDLFRDIQSLPRNAALRKLNDLIKR
:::.:::::.:::::::::::::::::::::::::::::.::::::::::::::::::::
NP_001 GKIINTPEVVRVYIGSFWSHPLLIPDNRKLFEAEEQDLFKDIQSLPRNAALRKLNDLIKR
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE0 ARLAKVHAYIISSLKKEMPSVFGKDNKKKELVNNLAEIYGRIEREHQISPGDFPNLKRMQ
:::::::::::::::::::.::::..:::::::::.::: .:::::::::::::.:..::
NP_001 ARLAKVHAYIISSLKKEMPNVFGKESKKKELVNNLGEIYQKIEREHQISPGDFPSLRKMQ
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE0 DQLQAQDFSKFQPLKSKLLEVVDDMLAHDIAQLMVLVRQEESQRPIQMVKGGAFEGTLHG
. ::.::::::: :: :::..::::::.:::.:::.:::::: : :.::::::.::..:
NP_001 ELLQTQDFSKFQALKPKLLDTVDDMLANDIARLMVMVRQEESLMPSQVVKGGAFDGTMNG
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE0 PFGHGYGEGAGEGIDDAEWVVARDKPMYDEIFYTLSPVDGKITGANAKKEMVRSKLPNSV
::::::::::::::::.::::..::: :::::::::::.:::::::::::::.:::::.:
NP_001 PFGHGYGEGAGEGIDDVEWVVGKDKPTYDEIFYTLSPVNGKITGANAKKEMVKSKLPNTV
430 440 450 460 470 480
490 500 510 520 530
pF1KE0 LGKIWKLADIDKDGMLDDDEFALANHLIKVKLEGHELPNELPAHLLPPSKRKVAE
:::::::::.::::.:::.::::::::::::::::::: .:: ::.:::::.
NP_001 LGKIWKLADVDKDGLLDDEEFALANHLIKVKLEGHELPADLPPHLVPPSKRRHE
490 500 510 520 530
>>NP_001269374 (OMIM: 605888) EH domain-containing prote (548 aa)
initn: 3220 init1: 3188 opt: 3188 Z-score: 3441.8 bits: 646.6 E(85289): 5.7e-185
Smith-Waterman score: 3188; 87.0% identity (97.2% similar) in 532 aa overlap (1-532:15-546)
10 20 30 40
pF1KE0 MFSWLGTDDRRRKDPEVFQTVSEGLKKLYKSKLLPLEEHYRFHEFH
::::.. : ::.:.::.::::.:::..:: .:::::::::::::::
NP_001 MEQPGTAASPVSGSMFSWVSKDARRKKEPELFQTVAEGLRQLYAQKLLPLEEHYRFHEFH
10 20 30 40 50 60
50 60 70 80 90 100
pF1KE0 SPALEDADFDNKPMVLLVGQYSTGKTTFIRYLLEQDFPGMRIGPEPTTDSFIAVMQGDME
::::::::::::::::::::::::::::::.:.::::::::::::::::::::::.: :
NP_001 SPALEDADFDNKPMVLLVGQYSTGKTTFIRHLIEQDFPGMRIGPEPTTDSFIAVMHGPTE
70 80 90 100 110 120
110 120 130 140 150 160
pF1KE0 GIIPGNALVVDPKKPFRKLNAFGNAFLNRFVCAQLPNPVLESISVIDTPGILSGEKQRIS
:..:::::::::..::::::::::::::::.:::::::::.:::.:::::::::::::::
NP_001 GVVPGNALVVDPRRPFRKLNAFGNAFLNRFMCAQLPNPVLDSISIIDTPGILSGEKQRIS
130 140 150 160 170 180
170 180 190 200 210 220
pF1KE0 RGYDFAAVLEWFAERVDRIILLFDAHKLDISDEFSEVIKALKNHEDKMRVVLNKADQIET
:::::::::::::::::::::::::::::::::::::::::::::::.::::::::::::
NP_001 RGYDFAAVLEWFAERVDRIILLFDAHKLDISDEFSEVIKALKNHEDKIRVVLNKADQIET
190 200 210 220 230 240
230 240 250 260 270 280
pF1KE0 QQLMRVYGALMWSLGKIVNTPEVIRVYIGSFWSHPLLIPDNRKLFEAEEQDLFRDIQSLP
:::::::::::::::::.:::::.:::::::::::::::::::::::::::::.::::::
NP_001 QQLMRVYGALMWSLGKIINTPEVVRVYIGSFWSHPLLIPDNRKLFEAEEQDLFKDIQSLP
250 260 270 280 290 300
290 300 310 320 330 340
pF1KE0 RNAALRKLNDLIKRARLAKVHAYIISSLKKEMPSVFGKDNKKKELVNNLAEIYGRIEREH
:::::::::::::::::::::::::::::::::.::::..:::::::::.::: .:::::
NP_001 RNAALRKLNDLIKRARLAKVHAYIISSLKKEMPNVFGKESKKKELVNNLGEIYQKIEREH
310 320 330 340 350 360
350 360 370 380 390 400
pF1KE0 QISPGDFPNLKRMQDQLQAQDFSKFQPLKSKLLEVVDDMLAHDIAQLMVLVRQEESQRPI
::::::::.:..::. ::.::::::: :: :::..::::::.:::.:::.:::::: :
NP_001 QISPGDFPSLRKMQELLQTQDFSKFQALKPKLLDTVDDMLANDIARLMVMVRQEESLMPS
370 380 390 400 410 420
410 420 430 440 450 460
pF1KE0 QMVKGGAFEGTLHGPFGHGYGEGAGEGIDDAEWVVARDKPMYDEIFYTLSPVDGKITGAN
:.::::::.::..:::::::::::::::::.::::..::: :::::::::::.:::::::
NP_001 QVVKGGAFDGTMNGPFGHGYGEGAGEGIDDVEWVVGKDKPTYDEIFYTLSPVNGKITGAN
430 440 450 460 470 480
470 480 490 500 510 520
pF1KE0 AKKEMVRSKLPNSVLGKIWKLADIDKDGMLDDDEFALANHLIKVKLEGHELPNELPAHLL
::::::.:::::.::::::::::.::::.:::.::::::::::::::::::: .:: ::.
NP_001 AKKEMVKSKLPNTVLGKIWKLADVDKDGLLDDEEFALANHLIKVKLEGHELPADLPPHLV
490 500 510 520 530 540
530
pF1KE0 PPSKRKVAE
:::::.
NP_001 PPSKRRHE
>>NP_644670 (OMIM: 605892) EH domain-containing protein (541 aa)
initn: 2751 init1: 2719 opt: 2748 Z-score: 2967.3 bits: 558.8 E(85289): 1.5e-158
Smith-Waterman score: 2748; 75.3% identity (90.7% similar) in 535 aa overlap (1-532:1-535)
10 20 30 40 50
pF1KE0 MFSWLGTD--DRRRKD-PEVFQTVSEGLKKLYKSKLLPLEEHYRFHEFHSPALEDADFDN
::::.: . :.: .. :::. ::..:: :.::::: ::::::::::::::::.:
NP_644 MFSWMGRQAGGRERAGGADAVQTVTGGLRSLYLRKVLPLEEAYRFHEFHSPALEDADFEN
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE0 KPMVLLVGQYSTGKTTFIRYLLEQDFPGMRIGPEPTTDSFIAVMQGDMEGIIPGNALVVD
:::.:::::::::::::::::::::::::::::::::::::::: :. :: ::::::::
NP_644 KPMILLVGQYSTGKTTFIRYLLEQDFPGMRIGPEPTTDSFIAVMYGETEGSTPGNALVVD
70 80 90 100 110 120
120 130 140 150 160 170
pF1KE0 PKKPFRKLNAFGNAFLNRFVCAQLPNPVLESISVIDTPGILSGEKQRISRGYDFAAVLEW
::::::::. :::::::::.:.:::: ::.::::::.::::::::::::::::: ::.:
NP_644 PKKPFRKLSRFGNAFLNRFMCSQLPNQVLKSISVIDSPGILSGEKQRISRGYDFCQVLQW
130 140 150 160 170 180
180 190 200 210 220 230
pF1KE0 FAERVDRIILLFDAHKLDISDEFSEVIKALKNHEDKMRVVLNKADQIETQQLMRVYGALM
:::::::::::::::::::::::::.:::.....::.:::::::::..::::::::::::
NP_644 FAERVDRIILLFDAHKLDISDEFSEAIKAFRGQDDKIRVVLNKADQVDTQQLMRVYGALM
190 200 210 220 230 240
240 250 260 270 280 290
pF1KE0 WSLGKIVNTPEVIRVYIGSFWSHPLLIPDNRKLFEAEEQDLFRDIQSLPRNAALRKLNDL
:::::..:::::.::::::::..:: :::.::::: :::::::::::..::.::::::
NP_644 WSLGKVINTPEVLRVYIGSFWAQPLQNTDNRRLFEAEAQDLFRDIQSLPQKAAVRKLNDL
250 260 270 280 290 300
300 310 320 330 340 350
pF1KE0 IKRARLAKVHAYIISSLKKEMPSVFGKDNKKKELVNNLAEIYGRIEREHQISPGDFPNLK
::::::::::::::: :::::::::::.:::.::.. : ::: ...::.::: ::::..:
NP_644 IKRARLAKVHAYIISYLKKEMPSVFGKENKKRELISRLPEIYIQLQREYQISAGDFPEVK
310 320 330 340 350 360
360 370 380 390 400 410
pF1KE0 RMQDQLQAQDFSKFQPLKSKLLEVVDDMLAHDIAQLMVLVRQEESQRPIQMVKGGAFEGT
::.::. ::.::. :: ::.:.::.::.. :. :: :. :::.. : :.:.::::.::
NP_644 AMQEQLENYDFTKFHSLKPKLIEAVDNMLSNKISPLMNLISQEETSTPTQLVQGGAFDGT
370 380 390 400 410 420
420 430 440 450 460 470
pF1KE0 LHGPFGHGYGEGAGEGIDDAEWVVARDKPMYDEIFYTLSPVDGKITGANAKKEMVRSKLP
.:::..:::::: :: :. :::::.:::.:::.::::::..:::.:.::::::: ::::
NP_644 TEGPFNQGYGEGAKEGADEEEWVVAKDKPVYDELFYTLSPINGKISGVNAKKEMVTSKLP
430 440 450 460 470 480
480 490 500 510 520 530
pF1KE0 NSVLGKIWKLADIDKDGMLDDDEFALANHLIKVKLEGHELPNELPAHLLPPSKRKVAE
:::::::::::: : :::::..:::::.::::.::.:.:::. :: ::.:::.::
NP_644 NSVLGKIWKLADCDCDGMLDEEEFALAKHLIKIKLDGYELPSSLPPHLVPPSHRKSLPKA
490 500 510 520 530 540
NP_644 D
>>NP_055416 (OMIM: 605890) EH domain-containing protein (543 aa)
initn: 2602 init1: 2142 opt: 2608 Z-score: 2816.3 bits: 530.8 E(85289): 3.9e-150
Smith-Waterman score: 2608; 71.7% identity (89.0% similar) in 537 aa overlap (1-532:1-537)
10 20 30 40 50 60
pF1KE0 MFSWLGTDDRRRKDPEVFQTVSEGLKKLYKSKLLPLEEHYRFHEFHSPALEDADFDNKPM
::::: : ..::...::. .::.::..::::::::::: ::::::::::::.:::
NP_055 MFSWLKRGGARGQQPEAIRTVTSALKELYRTKLLPLEEHYRFGAFHSPALEDADFDGKPM
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 VLLVGQYSTGKTTFIRYLLEQDFPGMRIGPEPTTDSFIAVMQGDMEGIIPGNALVVDPKK
::..::::::::.::.:::::. :: :.::::::: :.:::.:: :: .::::::::: :
NP_055 VLVAGQYSTGKTSFIQYLLEQEVPGSRVGPEPTTDCFVAVMHGDTEGTVPGNALVVDPDK
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE0 PFRKLNAFGNAFLNRFVCAQLPNPVLESISVIDTPGILSGEKQRISRGYDFAAVLEWFAE
:::::: :::.:::::.:::::: ::::::.::::::::: :::.:::::: :::.::::
NP_055 PFRKLNPFGNTFLNRFMCAQLPNQVLESISIIDTPGILSGAKQRVSRGYDFPAVLRWFAE
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE0 RVDRIILLFDAHKLDISDEFSEVIKALKNHEDKMRVVLNKADQIETQQLMRVYGALMWSL
::: ::::::::::.:::::::.: ::..::::.::::::::..::::::::::::::.:
NP_055 RVDLIILLFDAHKLEISDEFSEAIGALRGHEDKIRVVLNKADMVETQQLMRVYGALMWAL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE0 GKIVNTPEVIRVYIGSFWSHPLLIPDNRKLFEAEEQDLFRDIQSLPRNAALRKLNDLIKR
::.:.::::.:::::::::.:::.::::.::: ::::::::::.:::.:::::::::.::
NP_055 GKVVGTPEVLRVYIGSFWSQPLLVPDNRRLFELEEQDLFRDIQGLPRHAALRKLNDLVKR
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE0 ARLAKVHAYIISSLKKEMPSVFGKDNKKKELVNNLAEIYGRIEREHQISPGDFPNLKRMQ
:::..::::::: :::::::::::.::::.:. .: :...:. ::.:::::::. ..::
NP_055 ARLVRVHAYIISYLKKEMPSVFGKENKKKQLILKLPVIFAKIQLEHHISPGDFPDCQKMQ
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE0 DQLQAQDFSKFQPLKSKLLEVVDDMLAHDIAQLMVLVRQEESQRPIQMVKGGAFEGTLHG
. :.:.::.::. :: ::::..:.::.::::.:: :.:::: . :.::::::: :
NP_055 ELLMAHDFTKFHSLKPKLLEALDEMLTHDIAKLMPLLRQEELESTEVGVQGGAFEGTHMG
370 380 390 400 410 420
430 440 450 460 470
pF1KE0 PF---GHGYG-EGAGEGIDD-AEWVVARDKPMYDEIFYTLSPVDGKITGANAKKEMVRSK
:: : . : . :: :: :::::..:: ::::::.:.:.:::..:..:: :: .:
NP_055 PFVERGPDEAMEDGEEGSDDEAEWVVTKDKSKYDEIFYNLAPADGKLSGSKAKTWMVGTK
430 440 450 460 470 480
480 490 500 510 520 530
pF1KE0 LPNSVLGKIWKLADIDKDGMLDDDEFALANHLIKVKLEGHELPNELPAHLLPPSKRKVAE
:::::::.::::.:.:.::::::.:::::.:::..::::: :: .:: .:.:::::.
NP_055 LPNSVLGRIWKLSDVDRDGMLDDEEFALASHLIEAKLEGHGLPANLPRRLVPPSKRRHKG
490 500 510 520 530 540
NP_055 SAE
>>XP_016877589 (OMIM: 605892) PREDICTED: EH domain-conta (453 aa)
initn: 2330 init1: 2330 opt: 2330 Z-score: 2517.6 bits: 475.3 E(85289): 1.7e-133
Smith-Waterman score: 2330; 75.8% identity (91.7% similar) in 447 aa overlap (86-532:1-447)
60 70 80 90 100 110
pF1KE0 DNKPMVLLVGQYSTGKTTFIRYLLEQDFPGMRIGPEPTTDSFIAVMQGDMEGIIPGNALV
:::::::::::::::: :. :: ::::::
XP_016 MRIGPEPTTDSFIAVMYGETEGSTPGNALV
10 20 30
120 130 140 150 160 170
pF1KE0 VDPKKPFRKLNAFGNAFLNRFVCAQLPNPVLESISVIDTPGILSGEKQRISRGYDFAAVL
::::::::::. :::::::::.:.:::: ::.::::::.::::::::::::::::: ::
XP_016 VDPKKPFRKLSRFGNAFLNRFMCSQLPNQVLKSISVIDSPGILSGEKQRISRGYDFCQVL
40 50 60 70 80 90
180 190 200 210 220 230
pF1KE0 EWFAERVDRIILLFDAHKLDISDEFSEVIKALKNHEDKMRVVLNKADQIETQQLMRVYGA
.::::::::::::::::::::::::::.:::.....::.:::::::::..::::::::::
XP_016 QWFAERVDRIILLFDAHKLDISDEFSEAIKAFRGQDDKIRVVLNKADQVDTQQLMRVYGA
100 110 120 130 140 150
240 250 260 270 280 290
pF1KE0 LMWSLGKIVNTPEVIRVYIGSFWSHPLLIPDNRKLFEAEEQDLFRDIQSLPRNAALRKLN
:::::::..:::::.::::::::..:: :::.::::: :::::::::::..::.::::
XP_016 LMWSLGKVINTPEVLRVYIGSFWAQPLQNTDNRRLFEAEAQDLFRDIQSLPQKAAVRKLN
160 170 180 190 200 210
300 310 320 330 340 350
pF1KE0 DLIKRARLAKVHAYIISSLKKEMPSVFGKDNKKKELVNNLAEIYGRIEREHQISPGDFPN
::::::::::::::::: :::::::::::.:::.::.. : ::: ...::.::: ::::.
XP_016 DLIKRARLAKVHAYIISYLKKEMPSVFGKENKKRELISRLPEIYIQLQREYQISAGDFPE
220 230 240 250 260 270
360 370 380 390 400 410
pF1KE0 LKRMQDQLQAQDFSKFQPLKSKLLEVVDDMLAHDIAQLMVLVRQEESQRPIQMVKGGAFE
.: ::.::. ::.::. :: ::.:.::.::.. :. :: :. :::.. : :.:.::::.
XP_016 VKAMQEQLENYDFTKFHSLKPKLIEAVDNMLSNKISPLMNLISQEETSTPTQLVQGGAFD
280 290 300 310 320 330
420 430 440 450 460 470
pF1KE0 GTLHGPFGHGYGEGAGEGIDDAEWVVARDKPMYDEIFYTLSPVDGKITGANAKKEMVRSK
:: .:::..:::::: :: :. :::::.:::.:::.::::::..:::.:.::::::: ::
XP_016 GTTEGPFNQGYGEGAKEGADEEEWVVAKDKPVYDELFYTLSPINGKISGVNAKKEMVTSK
340 350 360 370 380 390
480 490 500 510 520 530
pF1KE0 LPNSVLGKIWKLADIDKDGMLDDDEFALANHLIKVKLEGHELPNELPAHLLPPSKRKVAE
:::::::::::::: : :::::..:::::.::::.::.:.:::. :: ::.:::.::
XP_016 LPNSVLGKIWKLADCDCDGMLDEEEFALAKHLIKIKLDGYELPSSLPPHLVPPSHRKSLP
400 410 420 430 440 450
XP_016 KAD
>>XP_011531108 (OMIM: 605891) PREDICTED: EH domain-conta (322 aa)
initn: 2131 init1: 2131 opt: 2131 Z-score: 2304.9 bits: 435.5 E(85289): 1.2e-121
Smith-Waterman score: 2131; 100.0% identity (100.0% similar) in 322 aa overlap (214-535:1-322)
190 200 210 220 230 240
pF1KE0 RIILLFDAHKLDISDEFSEVIKALKNHEDKMRVVLNKADQIETQQLMRVYGALMWSLGKI
::::::::::::::::::::::::::::::
XP_011 MRVVLNKADQIETQQLMRVYGALMWSLGKI
10 20 30
250 260 270 280 290 300
pF1KE0 VNTPEVIRVYIGSFWSHPLLIPDNRKLFEAEEQDLFRDIQSLPRNAALRKLNDLIKRARL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VNTPEVIRVYIGSFWSHPLLIPDNRKLFEAEEQDLFRDIQSLPRNAALRKLNDLIKRARL
40 50 60 70 80 90
310 320 330 340 350 360
pF1KE0 AKVHAYIISSLKKEMPSVFGKDNKKKELVNNLAEIYGRIEREHQISPGDFPNLKRMQDQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AKVHAYIISSLKKEMPSVFGKDNKKKELVNNLAEIYGRIEREHQISPGDFPNLKRMQDQL
100 110 120 130 140 150
370 380 390 400 410 420
pF1KE0 QAQDFSKFQPLKSKLLEVVDDMLAHDIAQLMVLVRQEESQRPIQMVKGGAFEGTLHGPFG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QAQDFSKFQPLKSKLLEVVDDMLAHDIAQLMVLVRQEESQRPIQMVKGGAFEGTLHGPFG
160 170 180 190 200 210
430 440 450 460 470 480
pF1KE0 HGYGEGAGEGIDDAEWVVARDKPMYDEIFYTLSPVDGKITGANAKKEMVRSKLPNSVLGK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HGYGEGAGEGIDDAEWVVARDKPMYDEIFYTLSPVDGKITGANAKKEMVRSKLPNSVLGK
220 230 240 250 260 270
490 500 510 520 530
pF1KE0 IWKLADIDKDGMLDDDEFALANHLIKVKLEGHELPNELPAHLLPPSKRKVAE
::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IWKLADIDKDGMLDDDEFALANHLIKVKLEGHELPNELPAHLLPPSKRKVAE
280 290 300 310 320
>>NP_001310597 (OMIM: 604992) sarcalumenin isoform 2 [Ho (431 aa)
initn: 551 init1: 385 opt: 755 Z-score: 819.4 bits: 161.0 E(85289): 6.6e-39
Smith-Waterman score: 755; 33.9% identity (69.6% similar) in 375 aa overlap (13-377:6-377)
10 20 30 40 50 60
pF1KE0 MFSWLGTDDRRRKDPEVFQTVSEGLKKLYKSKLLPLEEHYRFHEFHSPALEDADFDNKPM
: . ...: . :.:.:.:.. :::. :...:... . :... .:::
NP_001 MLNEDKPSDDYSAVLQRLRKIYHSSIKPLEQSYKYNELRQHEITDGEITSKPM
10 20 30 40 50
70 80 90 100 110
pF1KE0 VLLVGQYSTGKTTFIRYLL--EQDFPGMRIGPEPTTDSFIAVMQGDMEGIIPGNALVVDP
::..: .:.::.:.: ::: :. . : ::::. : ..:.: : : ....:
NP_001 VLFLGPWSVGKSTMINYLLGLENTRYQLYTGAEPTTSEFTVLMHGPKLKTIEGIVMAADS
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE0 KKPFRKLNAFGNAFLNRFVCAQLPNPVLESISVIDTPGILSGEKQRISRGYDFAAVLEWF
. : :. ::. ::.... ..:. .:: .. .:::::. ..::. ::: : : .::
NP_001 ARSFSPLEKFGQNFLEKLIGIEVPHKLLERVTFVDTPGIIENRKQQ-ERGYPFNDVCQWF
120 130 140 150 160 170
180 190 200 210 220 230
pF1KE0 AERVDRIILLFDAHKLDISDEFSEVIKALKNHEDKMRVVLNKADQIETQQLMRVYGALMW
.:.: :...:: :::.. :. ... ::..:...:..:::::.. ::.::::::::.:
NP_001 IDRADLIFVVFDPTKLDVGLELEMLFRQLKGRESQIRIILNKADNLATQMLMRVYGALFW
180 190 200 210 220 230
240 250 260 270 280 290
pF1KE0 SLGKIVNTPEVIRVYIGSFWSHPLLIPDNRKLFEAEEQDLFRDIQSLPRNAALRKLNDLI
::. ..:. : :::..::: . ...:: :: .:..:.... .: :. .
NP_001 SLAPLINVTEPPRVYVSSFWPQEYKPDTHQELFLQEEISLLEDLNQVIENRLENKIAFIR
240 250 260 270 280 290
300 310 320 330 340 350
pF1KE0 KRARLAKVHAYIIS----SLKKEMPSVFGKDNKK--KELVNNLAE--IYGRIEREHQISP
..: ...:: ... . : .: .: .:.. :..:.. . :. : . ..:
NP_001 QHAIRVRIHALLVDRYLQTYKDKM--TFFSDGELVFKDIVEDPDKFYIFKTILAKTNVSK
300 310 320 330 340 350
360 370 380 390 400 410
pF1KE0 GDFPNLKRMQDQLQAQDFSKFQPLKSKLLEVVDDMLAHDIAQLMVLVRQEESQRPIQMVK
:.:: . ..: . . .:.:. :...
NP_001 FDLPNREAYKDFFGINPISSFKLLSQQCSYMGGCFLEKIERAITQELPGLLGSLGLGKNP
360 370 380 390 400 410
535 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 03:30:17 2016 done: Fri Nov 4 03:30:18 2016
Total Scan time: 8.830 Total Display time: 0.090
Function used was FASTA [36.3.4 Apr, 2011]