Result of FASTA (omim) for
pFN21AE0075
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE0075, 1447 aa
1>>>pF1KE0075 1447 - 1447 aa - 1447 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 9.8199+/-0.000471; mu= 2.9974+/- 0.029
mean_var=264.3401+/-55.524, 0's: 0 Z-trim(118.8): 52 B-trim: 1293 in 2/51
Lambda= 0.078885
statistics sampled from 32000 (32055) to 32000 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.7), E-opt: 0.2 (0.376), width: 16
Scan time: 19.710
The best scores are: opt bits E(85289)
NP_000255 (OMIM: 109400,601309,605462,610828) prot (1447) 9793 1129.3 0
NP_001077072 (OMIM: 109400,601309,605462,610828) p (1446) 9327 1076.2 0
NP_001077071 (OMIM: 109400,601309,605462,610828) p (1381) 9321 1075.5 0
NP_001077075 (OMIM: 109400,601309,605462,610828) p (1296) 8768 1012.6 0
NP_001077073 (OMIM: 109400,601309,605462,610828) p (1296) 8768 1012.6 0
NP_001077074 (OMIM: 109400,601309,605462,610828) p (1296) 8768 1012.6 0
NP_001077076 (OMIM: 109400,601309,605462,610828) p (1296) 8768 1012.6 0
NP_001159764 (OMIM: 109400,155255,603673,605462) p (1146) 2010 243.4 7.4e-63
NP_003729 (OMIM: 109400,155255,603673,605462) prot (1203) 2010 243.5 7.6e-63
XP_011524317 (OMIM: 257220,607623) PREDICTED: Niem (1148) 439 64.7 4.9e-09
XP_016881276 (OMIM: 257220,607623) PREDICTED: Niem (1256) 439 64.7 5.2e-09
XP_016881275 (OMIM: 257220,607623) PREDICTED: Niem (1264) 439 64.7 5.3e-09
XP_016881274 (OMIM: 257220,607623) PREDICTED: Niem (1273) 439 64.7 5.3e-09
XP_006722542 (OMIM: 257220,607623) PREDICTED: Niem (1273) 439 64.7 5.3e-09
NP_000262 (OMIM: 257220,607623) Niemann-Pick C1 pr (1278) 439 64.7 5.3e-09
XP_016881273 (OMIM: 257220,607623) PREDICTED: Niem (1281) 439 64.7 5.3e-09
XP_005258336 (OMIM: 257220,607623) PREDICTED: Niem (1286) 439 64.7 5.3e-09
XP_005258335 (OMIM: 257220,607623) PREDICTED: Niem (1295) 439 64.7 5.4e-09
XP_005258334 (OMIM: 257220,607623) PREDICTED: Niem (1303) 439 64.7 5.4e-09
NP_001095118 (OMIM: 608010) Niemann-Pick C1-like p (1332) 374 57.3 9.2e-07
NP_037521 (OMIM: 608010) Niemann-Pick C1-like prot (1359) 374 57.3 9.4e-07
XP_011513630 (OMIM: 608010) PREDICTED: Niemann-Pic ( 785) 367 56.3 1.1e-06
XP_016866382 (OMIM: 616908) PREDICTED: patched dom ( 843) 291 47.7 0.00045
NP_001013754 (OMIM: 616908) patched domain-contain ( 846) 291 47.7 0.00045
XP_016866381 (OMIM: 616908) PREDICTED: patched dom ( 901) 291 47.7 0.00048
XP_016866380 (OMIM: 616908) PREDICTED: patched dom ( 904) 291 47.7 0.00048
NP_775766 (OMIM: 300828,300830) patched domain-con ( 888) 271 45.5 0.0023
XP_011543751 (OMIM: 300828,300830) PREDICTED: patc ( 888) 271 45.5 0.0023
XP_011512941 (OMIM: 616908) PREDICTED: patched dom ( 593) 250 42.9 0.0087
>>NP_000255 (OMIM: 109400,601309,605462,610828) protein (1447 aa)
initn: 9793 init1: 9793 opt: 9793 Z-score: 6035.1 bits: 1129.3 E(85289): 0
Smith-Waterman score: 9793; 100.0% identity (100.0% similar) in 1447 aa overlap (1-1447:1-1447)
10 20 30 40 50 60
pF1KE0 MASAGNAAEPQDRGGGGSGCIGAPGRPAGGGRRRRTGGLRRAAAPDRDYLHRPSYCDAAF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 MASAGNAAEPQDRGGGGSGCIGAPGRPAGGGRRRRTGGLRRAAAPDRDYLHRPSYCDAAF
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 ALEQISKGKATGRKAPLWLRAKFQRLLFKLGCYIQKNCGKFLVVGLLIFGAFAVGLKAAN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 ALEQISKGKATGRKAPLWLRAKFQRLLFKLGCYIQKNCGKFLVVGLLIFGAFAVGLKAAN
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE0 LETNVEELWVEVGGRVSRELNYTRQKIGEEAMFNPQLMIQTPKEEGANVLTTEALLQHLD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 LETNVEELWVEVGGRVSRELNYTRQKIGEEAMFNPQLMIQTPKEEGANVLTTEALLQHLD
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE0 SALQASRVHVYMYNRQWKLEHLCYKSGELITETGYMDQIIEYLYPCLIITPLDCFWEGAK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 SALQASRVHVYMYNRQWKLEHLCYKSGELITETGYMDQIIEYLYPCLIITPLDCFWEGAK
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE0 LQSGTAYLLGKPPLRWTNFDPLEFLEELKKINYQVDSWEEMLNKAEVGHGYMDRPCLNPA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 LQSGTAYLLGKPPLRWTNFDPLEFLEELKKINYQVDSWEEMLNKAEVGHGYMDRPCLNPA
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE0 DPDCPATAPNKNSTKPLDMALVLNGGCHGLSRKYMHWQEELIVGGTVKNSTGKLVSAHAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 DPDCPATAPNKNSTKPLDMALVLNGGCHGLSRKYMHWQEELIVGGTVKNSTGKLVSAHAL
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE0 QTMFQLMTPKQMYEHFKGYEYVSHINWNEDKAAAILEAWQRTYVEVVHQSVAQNSTQKVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 QTMFQLMTPKQMYEHFKGYEYVSHINWNEDKAAAILEAWQRTYVEVVHQSVAQNSTQKVL
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE0 SFTTTTLDDILKSFSDVSVIRVASGYLLMLAYACLTMLRWDCSKSQGAVGLAGVLLVALS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 SFTTTTLDDILKSFSDVSVIRVASGYLLMLAYACLTMLRWDCSKSQGAVGLAGVLLVALS
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE0 VAAGLGLCSLIGISFNAATTQVLPFLALGVGVDDVFLLAHAFSETGQNKRIPFEDRTGEC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 VAAGLGLCSLIGISFNAATTQVLPFLALGVGVDDVFLLAHAFSETGQNKRIPFEDRTGEC
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE0 LKRTGASVALTSISNVTAFFMAALIPIPALRAFSLQAAVVVVFNFAMVLLIFPAILSMDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 LKRTGASVALTSISNVTAFFMAALIPIPALRAFSLQAAVVVVFNFAMVLLIFPAILSMDL
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE0 YRREDRRLDIFCCFTSPCVSRVIQVEPQAYTDTHDNTRYSPPPPYSSHSFAHETQITMQS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 YRREDRRLDIFCCFTSPCVSRVIQVEPQAYTDTHDNTRYSPPPPYSSHSFAHETQITMQS
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE0 TVQLRTEYDPHTHVYYTTAEPRSEISVQPVTVTQDTLSCQSPESTSSTRDLLSQFSDSSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 TVQLRTEYDPHTHVYYTTAEPRSEISVQPVTVTQDTLSCQSPESTSSTRDLLSQFSDSSL
670 680 690 700 710 720
730 740 750 760 770 780
pF1KE0 HCLEPPCTKWTLSSFAEKHYAPFLLKPKAKVVVIFLFLGLLGVSLYGTTRVRDGLDLTDI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 HCLEPPCTKWTLSSFAEKHYAPFLLKPKAKVVVIFLFLGLLGVSLYGTTRVRDGLDLTDI
730 740 750 760 770 780
790 800 810 820 830 840
pF1KE0 VPRETREYDFIAAQFKYFSFYNMYIVTQKADYPNIQHLLYDLHRSFSNVKYVMLEENKQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 VPRETREYDFIAAQFKYFSFYNMYIVTQKADYPNIQHLLYDLHRSFSNVKYVMLEENKQL
790 800 810 820 830 840
850 860 870 880 890 900
pF1KE0 PKMWLHYFRDWLQGLQDAFDSDWETGKIMPNNYKNGSDDGVLAYKLLVQTGSRDKPIDIS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 PKMWLHYFRDWLQGLQDAFDSDWETGKIMPNNYKNGSDDGVLAYKLLVQTGSRDKPIDIS
850 860 870 880 890 900
910 920 930 940 950 960
pF1KE0 QLTKQRLVDADGIINPSAFYIYLTAWVSNDPVAYAASQANIRPHRPEWVHDKADYMPETR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 QLTKQRLVDADGIINPSAFYIYLTAWVSNDPVAYAASQANIRPHRPEWVHDKADYMPETR
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KE0 LRIPAAEPIEYAQFPFYLNGLRDTSDFVEAIEKVRTICSNYTSLGLSSYPNGYPFLFWEQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 LRIPAAEPIEYAQFPFYLNGLRDTSDFVEAIEKVRTICSNYTSLGLSSYPNGYPFLFWEQ
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KE0 YIGLRHWLLLFISVVLACTFLVCAVFLLNPWTAGIIVMVLALMTVELFGMMGLIGIKLSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 YIGLRHWLLLFISVVLACTFLVCAVFLLNPWTAGIIVMVLALMTVELFGMMGLIGIKLSA
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KE0 VPVVILIASVGIGVEFTVHVALAFLTAIGDKNRRAVLALEHMFAPVLDGAVSTLLGVLML
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 VPVVILIASVGIGVEFTVHVALAFLTAIGDKNRRAVLALEHMFAPVLDGAVSTLLGVLML
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KE0 AGSEFDFIVRYFFAVLAILTILGVLNGLVLLPVLLSFFGPYPEVSPANGLNRLPTPSPEP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 AGSEFDFIVRYFFAVLAILTILGVLNGLVLLPVLLSFFGPYPEVSPANGLNRLPTPSPEP
1150 1160 1170 1180 1190 1200
1210 1220 1230 1240 1250 1260
pF1KE0 PPSVVRFAMPPGHTHSGSDSSDSEYSSQTTVSGLSEELRHYEAQQGAGGPAHQVIVEATE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 PPSVVRFAMPPGHTHSGSDSSDSEYSSQTTVSGLSEELRHYEAQQGAGGPAHQVIVEATE
1210 1220 1230 1240 1250 1260
1270 1280 1290 1300 1310 1320
pF1KE0 NPVFAHSTVVHPESRHHPPSNPRQQPHLDSGSLPPGRQGQQPRRDPPREGLWPPPYRPRR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 NPVFAHSTVVHPESRHHPPSNPRQQPHLDSGSLPPGRQGQQPRRDPPREGLWPPPYRPRR
1270 1280 1290 1300 1310 1320
1330 1340 1350 1360 1370 1380
pF1KE0 DAFEISTEGHSGPSNRARWGPRGARSHNPRNPASTAMGSSVPGYCQPITTVTASASVTVA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 DAFEISTEGHSGPSNRARWGPRGARSHNPRNPASTAMGSSVPGYCQPITTVTASASVTVA
1330 1340 1350 1360 1370 1380
1390 1400 1410 1420 1430 1440
pF1KE0 VHPPPVPGPGRNPRGGLCPGYPETDHGLFEDPHVPFHVRCERRDSKVEVIELQDVECEER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 VHPPPVPGPGRNPRGGLCPGYPETDHGLFEDPHVPFHVRCERRDSKVEVIELQDVECEER
1390 1400 1410 1420 1430 1440
pF1KE0 PRGSSSN
:::::::
NP_000 PRGSSSN
>>NP_001077072 (OMIM: 109400,601309,605462,610828) prote (1446 aa)
initn: 9327 init1: 9327 opt: 9327 Z-score: 5748.5 bits: 1076.2 E(85289): 0
Smith-Waterman score: 9327; 100.0% identity (100.0% similar) in 1381 aa overlap (67-1447:66-1446)
40 50 60 70 80 90
pF1KE0 GGLRRAAAPDRDYLHRPSYCDAAFALEQISKGKATGRKAPLWLRAKFQRLLFKLGCYIQK
::::::::::::::::::::::::::::::
NP_001 FCKDGGGGEEEEENGGEEKDDRGDKETRSDKGKATGRKAPLWLRAKFQRLLFKLGCYIQK
40 50 60 70 80 90
100 110 120 130 140 150
pF1KE0 NCGKFLVVGLLIFGAFAVGLKAANLETNVEELWVEVGGRVSRELNYTRQKIGEEAMFNPQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NCGKFLVVGLLIFGAFAVGLKAANLETNVEELWVEVGGRVSRELNYTRQKIGEEAMFNPQ
100 110 120 130 140 150
160 170 180 190 200 210
pF1KE0 LMIQTPKEEGANVLTTEALLQHLDSALQASRVHVYMYNRQWKLEHLCYKSGELITETGYM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LMIQTPKEEGANVLTTEALLQHLDSALQASRVHVYMYNRQWKLEHLCYKSGELITETGYM
160 170 180 190 200 210
220 230 240 250 260 270
pF1KE0 DQIIEYLYPCLIITPLDCFWEGAKLQSGTAYLLGKPPLRWTNFDPLEFLEELKKINYQVD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DQIIEYLYPCLIITPLDCFWEGAKLQSGTAYLLGKPPLRWTNFDPLEFLEELKKINYQVD
220 230 240 250 260 270
280 290 300 310 320 330
pF1KE0 SWEEMLNKAEVGHGYMDRPCLNPADPDCPATAPNKNSTKPLDMALVLNGGCHGLSRKYMH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SWEEMLNKAEVGHGYMDRPCLNPADPDCPATAPNKNSTKPLDMALVLNGGCHGLSRKYMH
280 290 300 310 320 330
340 350 360 370 380 390
pF1KE0 WQEELIVGGTVKNSTGKLVSAHALQTMFQLMTPKQMYEHFKGYEYVSHINWNEDKAAAIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 WQEELIVGGTVKNSTGKLVSAHALQTMFQLMTPKQMYEHFKGYEYVSHINWNEDKAAAIL
340 350 360 370 380 390
400 410 420 430 440 450
pF1KE0 EAWQRTYVEVVHQSVAQNSTQKVLSFTTTTLDDILKSFSDVSVIRVASGYLLMLAYACLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EAWQRTYVEVVHQSVAQNSTQKVLSFTTTTLDDILKSFSDVSVIRVASGYLLMLAYACLT
400 410 420 430 440 450
460 470 480 490 500 510
pF1KE0 MLRWDCSKSQGAVGLAGVLLVALSVAAGLGLCSLIGISFNAATTQVLPFLALGVGVDDVF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MLRWDCSKSQGAVGLAGVLLVALSVAAGLGLCSLIGISFNAATTQVLPFLALGVGVDDVF
460 470 480 490 500 510
520 530 540 550 560 570
pF1KE0 LLAHAFSETGQNKRIPFEDRTGECLKRTGASVALTSISNVTAFFMAALIPIPALRAFSLQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LLAHAFSETGQNKRIPFEDRTGECLKRTGASVALTSISNVTAFFMAALIPIPALRAFSLQ
520 530 540 550 560 570
580 590 600 610 620 630
pF1KE0 AAVVVVFNFAMVLLIFPAILSMDLYRREDRRLDIFCCFTSPCVSRVIQVEPQAYTDTHDN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AAVVVVFNFAMVLLIFPAILSMDLYRREDRRLDIFCCFTSPCVSRVIQVEPQAYTDTHDN
580 590 600 610 620 630
640 650 660 670 680 690
pF1KE0 TRYSPPPPYSSHSFAHETQITMQSTVQLRTEYDPHTHVYYTTAEPRSEISVQPVTVTQDT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TRYSPPPPYSSHSFAHETQITMQSTVQLRTEYDPHTHVYYTTAEPRSEISVQPVTVTQDT
640 650 660 670 680 690
700 710 720 730 740 750
pF1KE0 LSCQSPESTSSTRDLLSQFSDSSLHCLEPPCTKWTLSSFAEKHYAPFLLKPKAKVVVIFL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LSCQSPESTSSTRDLLSQFSDSSLHCLEPPCTKWTLSSFAEKHYAPFLLKPKAKVVVIFL
700 710 720 730 740 750
760 770 780 790 800 810
pF1KE0 FLGLLGVSLYGTTRVRDGLDLTDIVPRETREYDFIAAQFKYFSFYNMYIVTQKADYPNIQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FLGLLGVSLYGTTRVRDGLDLTDIVPRETREYDFIAAQFKYFSFYNMYIVTQKADYPNIQ
760 770 780 790 800 810
820 830 840 850 860 870
pF1KE0 HLLYDLHRSFSNVKYVMLEENKQLPKMWLHYFRDWLQGLQDAFDSDWETGKIMPNNYKNG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HLLYDLHRSFSNVKYVMLEENKQLPKMWLHYFRDWLQGLQDAFDSDWETGKIMPNNYKNG
820 830 840 850 860 870
880 890 900 910 920 930
pF1KE0 SDDGVLAYKLLVQTGSRDKPIDISQLTKQRLVDADGIINPSAFYIYLTAWVSNDPVAYAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SDDGVLAYKLLVQTGSRDKPIDISQLTKQRLVDADGIINPSAFYIYLTAWVSNDPVAYAA
880 890 900 910 920 930
940 950 960 970 980 990
pF1KE0 SQANIRPHRPEWVHDKADYMPETRLRIPAAEPIEYAQFPFYLNGLRDTSDFVEAIEKVRT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SQANIRPHRPEWVHDKADYMPETRLRIPAAEPIEYAQFPFYLNGLRDTSDFVEAIEKVRT
940 950 960 970 980 990
1000 1010 1020 1030 1040 1050
pF1KE0 ICSNYTSLGLSSYPNGYPFLFWEQYIGLRHWLLLFISVVLACTFLVCAVFLLNPWTAGII
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ICSNYTSLGLSSYPNGYPFLFWEQYIGLRHWLLLFISVVLACTFLVCAVFLLNPWTAGII
1000 1010 1020 1030 1040 1050
1060 1070 1080 1090 1100 1110
pF1KE0 VMVLALMTVELFGMMGLIGIKLSAVPVVILIASVGIGVEFTVHVALAFLTAIGDKNRRAV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VMVLALMTVELFGMMGLIGIKLSAVPVVILIASVGIGVEFTVHVALAFLTAIGDKNRRAV
1060 1070 1080 1090 1100 1110
1120 1130 1140 1150 1160 1170
pF1KE0 LALEHMFAPVLDGAVSTLLGVLMLAGSEFDFIVRYFFAVLAILTILGVLNGLVLLPVLLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LALEHMFAPVLDGAVSTLLGVLMLAGSEFDFIVRYFFAVLAILTILGVLNGLVLLPVLLS
1120 1130 1140 1150 1160 1170
1180 1190 1200 1210 1220 1230
pF1KE0 FFGPYPEVSPANGLNRLPTPSPEPPPSVVRFAMPPGHTHSGSDSSDSEYSSQTTVSGLSE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FFGPYPEVSPANGLNRLPTPSPEPPPSVVRFAMPPGHTHSGSDSSDSEYSSQTTVSGLSE
1180 1190 1200 1210 1220 1230
1240 1250 1260 1270 1280 1290
pF1KE0 ELRHYEAQQGAGGPAHQVIVEATENPVFAHSTVVHPESRHHPPSNPRQQPHLDSGSLPPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ELRHYEAQQGAGGPAHQVIVEATENPVFAHSTVVHPESRHHPPSNPRQQPHLDSGSLPPG
1240 1250 1260 1270 1280 1290
1300 1310 1320 1330 1340 1350
pF1KE0 RQGQQPRRDPPREGLWPPPYRPRRDAFEISTEGHSGPSNRARWGPRGARSHNPRNPASTA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RQGQQPRRDPPREGLWPPPYRPRRDAFEISTEGHSGPSNRARWGPRGARSHNPRNPASTA
1300 1310 1320 1330 1340 1350
1360 1370 1380 1390 1400 1410
pF1KE0 MGSSVPGYCQPITTVTASASVTVAVHPPPVPGPGRNPRGGLCPGYPETDHGLFEDPHVPF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MGSSVPGYCQPITTVTASASVTVAVHPPPVPGPGRNPRGGLCPGYPETDHGLFEDPHVPF
1360 1370 1380 1390 1400 1410
1420 1430 1440
pF1KE0 HVRCERRDSKVEVIELQDVECEERPRGSSSN
:::::::::::::::::::::::::::::::
NP_001 HVRCERRDSKVEVIELQDVECEERPRGSSSN
1420 1430 1440
>>NP_001077071 (OMIM: 109400,601309,605462,610828) prote (1381 aa)
initn: 9321 init1: 9321 opt: 9321 Z-score: 5745.1 bits: 1075.5 E(85289): 0
Smith-Waterman score: 9321; 100.0% identity (100.0% similar) in 1380 aa overlap (68-1447:2-1381)
40 50 60 70 80 90
pF1KE0 GLRRAAAPDRDYLHRPSYCDAAFALEQISKGKATGRKAPLWLRAKFQRLLFKLGCYIQKN
::::::::::::::::::::::::::::::
NP_001 MGKATGRKAPLWLRAKFQRLLFKLGCYIQKN
10 20 30
100 110 120 130 140 150
pF1KE0 CGKFLVVGLLIFGAFAVGLKAANLETNVEELWVEVGGRVSRELNYTRQKIGEEAMFNPQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CGKFLVVGLLIFGAFAVGLKAANLETNVEELWVEVGGRVSRELNYTRQKIGEEAMFNPQL
40 50 60 70 80 90
160 170 180 190 200 210
pF1KE0 MIQTPKEEGANVLTTEALLQHLDSALQASRVHVYMYNRQWKLEHLCYKSGELITETGYMD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MIQTPKEEGANVLTTEALLQHLDSALQASRVHVYMYNRQWKLEHLCYKSGELITETGYMD
100 110 120 130 140 150
220 230 240 250 260 270
pF1KE0 QIIEYLYPCLIITPLDCFWEGAKLQSGTAYLLGKPPLRWTNFDPLEFLEELKKINYQVDS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QIIEYLYPCLIITPLDCFWEGAKLQSGTAYLLGKPPLRWTNFDPLEFLEELKKINYQVDS
160 170 180 190 200 210
280 290 300 310 320 330
pF1KE0 WEEMLNKAEVGHGYMDRPCLNPADPDCPATAPNKNSTKPLDMALVLNGGCHGLSRKYMHW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 WEEMLNKAEVGHGYMDRPCLNPADPDCPATAPNKNSTKPLDMALVLNGGCHGLSRKYMHW
220 230 240 250 260 270
340 350 360 370 380 390
pF1KE0 QEELIVGGTVKNSTGKLVSAHALQTMFQLMTPKQMYEHFKGYEYVSHINWNEDKAAAILE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QEELIVGGTVKNSTGKLVSAHALQTMFQLMTPKQMYEHFKGYEYVSHINWNEDKAAAILE
280 290 300 310 320 330
400 410 420 430 440 450
pF1KE0 AWQRTYVEVVHQSVAQNSTQKVLSFTTTTLDDILKSFSDVSVIRVASGYLLMLAYACLTM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AWQRTYVEVVHQSVAQNSTQKVLSFTTTTLDDILKSFSDVSVIRVASGYLLMLAYACLTM
340 350 360 370 380 390
460 470 480 490 500 510
pF1KE0 LRWDCSKSQGAVGLAGVLLVALSVAAGLGLCSLIGISFNAATTQVLPFLALGVGVDDVFL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LRWDCSKSQGAVGLAGVLLVALSVAAGLGLCSLIGISFNAATTQVLPFLALGVGVDDVFL
400 410 420 430 440 450
520 530 540 550 560 570
pF1KE0 LAHAFSETGQNKRIPFEDRTGECLKRTGASVALTSISNVTAFFMAALIPIPALRAFSLQA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LAHAFSETGQNKRIPFEDRTGECLKRTGASVALTSISNVTAFFMAALIPIPALRAFSLQA
460 470 480 490 500 510
580 590 600 610 620 630
pF1KE0 AVVVVFNFAMVLLIFPAILSMDLYRREDRRLDIFCCFTSPCVSRVIQVEPQAYTDTHDNT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AVVVVFNFAMVLLIFPAILSMDLYRREDRRLDIFCCFTSPCVSRVIQVEPQAYTDTHDNT
520 530 540 550 560 570
640 650 660 670 680 690
pF1KE0 RYSPPPPYSSHSFAHETQITMQSTVQLRTEYDPHTHVYYTTAEPRSEISVQPVTVTQDTL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RYSPPPPYSSHSFAHETQITMQSTVQLRTEYDPHTHVYYTTAEPRSEISVQPVTVTQDTL
580 590 600 610 620 630
700 710 720 730 740 750
pF1KE0 SCQSPESTSSTRDLLSQFSDSSLHCLEPPCTKWTLSSFAEKHYAPFLLKPKAKVVVIFLF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SCQSPESTSSTRDLLSQFSDSSLHCLEPPCTKWTLSSFAEKHYAPFLLKPKAKVVVIFLF
640 650 660 670 680 690
760 770 780 790 800 810
pF1KE0 LGLLGVSLYGTTRVRDGLDLTDIVPRETREYDFIAAQFKYFSFYNMYIVTQKADYPNIQH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LGLLGVSLYGTTRVRDGLDLTDIVPRETREYDFIAAQFKYFSFYNMYIVTQKADYPNIQH
700 710 720 730 740 750
820 830 840 850 860 870
pF1KE0 LLYDLHRSFSNVKYVMLEENKQLPKMWLHYFRDWLQGLQDAFDSDWETGKIMPNNYKNGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LLYDLHRSFSNVKYVMLEENKQLPKMWLHYFRDWLQGLQDAFDSDWETGKIMPNNYKNGS
760 770 780 790 800 810
880 890 900 910 920 930
pF1KE0 DDGVLAYKLLVQTGSRDKPIDISQLTKQRLVDADGIINPSAFYIYLTAWVSNDPVAYAAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DDGVLAYKLLVQTGSRDKPIDISQLTKQRLVDADGIINPSAFYIYLTAWVSNDPVAYAAS
820 830 840 850 860 870
940 950 960 970 980 990
pF1KE0 QANIRPHRPEWVHDKADYMPETRLRIPAAEPIEYAQFPFYLNGLRDTSDFVEAIEKVRTI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QANIRPHRPEWVHDKADYMPETRLRIPAAEPIEYAQFPFYLNGLRDTSDFVEAIEKVRTI
880 890 900 910 920 930
1000 1010 1020 1030 1040 1050
pF1KE0 CSNYTSLGLSSYPNGYPFLFWEQYIGLRHWLLLFISVVLACTFLVCAVFLLNPWTAGIIV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CSNYTSLGLSSYPNGYPFLFWEQYIGLRHWLLLFISVVLACTFLVCAVFLLNPWTAGIIV
940 950 960 970 980 990
1060 1070 1080 1090 1100 1110
pF1KE0 MVLALMTVELFGMMGLIGIKLSAVPVVILIASVGIGVEFTVHVALAFLTAIGDKNRRAVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MVLALMTVELFGMMGLIGIKLSAVPVVILIASVGIGVEFTVHVALAFLTAIGDKNRRAVL
1000 1010 1020 1030 1040 1050
1120 1130 1140 1150 1160 1170
pF1KE0 ALEHMFAPVLDGAVSTLLGVLMLAGSEFDFIVRYFFAVLAILTILGVLNGLVLLPVLLSF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ALEHMFAPVLDGAVSTLLGVLMLAGSEFDFIVRYFFAVLAILTILGVLNGLVLLPVLLSF
1060 1070 1080 1090 1100 1110
1180 1190 1200 1210 1220 1230
pF1KE0 FGPYPEVSPANGLNRLPTPSPEPPPSVVRFAMPPGHTHSGSDSSDSEYSSQTTVSGLSEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FGPYPEVSPANGLNRLPTPSPEPPPSVVRFAMPPGHTHSGSDSSDSEYSSQTTVSGLSEE
1120 1130 1140 1150 1160 1170
1240 1250 1260 1270 1280 1290
pF1KE0 LRHYEAQQGAGGPAHQVIVEATENPVFAHSTVVHPESRHHPPSNPRQQPHLDSGSLPPGR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LRHYEAQQGAGGPAHQVIVEATENPVFAHSTVVHPESRHHPPSNPRQQPHLDSGSLPPGR
1180 1190 1200 1210 1220 1230
1300 1310 1320 1330 1340 1350
pF1KE0 QGQQPRRDPPREGLWPPPYRPRRDAFEISTEGHSGPSNRARWGPRGARSHNPRNPASTAM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QGQQPRRDPPREGLWPPPYRPRRDAFEISTEGHSGPSNRARWGPRGARSHNPRNPASTAM
1240 1250 1260 1270 1280 1290
1360 1370 1380 1390 1400 1410
pF1KE0 GSSVPGYCQPITTVTASASVTVAVHPPPVPGPGRNPRGGLCPGYPETDHGLFEDPHVPFH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GSSVPGYCQPITTVTASASVTVAVHPPPVPGPGRNPRGGLCPGYPETDHGLFEDPHVPFH
1300 1310 1320 1330 1340 1350
1420 1430 1440
pF1KE0 VRCERRDSKVEVIELQDVECEERPRGSSSN
::::::::::::::::::::::::::::::
NP_001 VRCERRDSKVEVIELQDVECEERPRGSSSN
1360 1370 1380
>>NP_001077075 (OMIM: 109400,601309,605462,610828) prote (1296 aa)
initn: 8768 init1: 8768 opt: 8768 Z-score: 5405.4 bits: 1012.6 E(85289): 0
Smith-Waterman score: 8768; 100.0% identity (100.0% similar) in 1296 aa overlap (152-1447:1-1296)
130 140 150 160 170 180
pF1KE0 ETNVEELWVEVGGRVSRELNYTRQKIGEEAMFNPQLMIQTPKEEGANVLTTEALLQHLDS
::::::::::::::::::::::::::::::
NP_001 MFNPQLMIQTPKEEGANVLTTEALLQHLDS
10 20 30
190 200 210 220 230 240
pF1KE0 ALQASRVHVYMYNRQWKLEHLCYKSGELITETGYMDQIIEYLYPCLIITPLDCFWEGAKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ALQASRVHVYMYNRQWKLEHLCYKSGELITETGYMDQIIEYLYPCLIITPLDCFWEGAKL
40 50 60 70 80 90
250 260 270 280 290 300
pF1KE0 QSGTAYLLGKPPLRWTNFDPLEFLEELKKINYQVDSWEEMLNKAEVGHGYMDRPCLNPAD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QSGTAYLLGKPPLRWTNFDPLEFLEELKKINYQVDSWEEMLNKAEVGHGYMDRPCLNPAD
100 110 120 130 140 150
310 320 330 340 350 360
pF1KE0 PDCPATAPNKNSTKPLDMALVLNGGCHGLSRKYMHWQEELIVGGTVKNSTGKLVSAHALQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PDCPATAPNKNSTKPLDMALVLNGGCHGLSRKYMHWQEELIVGGTVKNSTGKLVSAHALQ
160 170 180 190 200 210
370 380 390 400 410 420
pF1KE0 TMFQLMTPKQMYEHFKGYEYVSHINWNEDKAAAILEAWQRTYVEVVHQSVAQNSTQKVLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TMFQLMTPKQMYEHFKGYEYVSHINWNEDKAAAILEAWQRTYVEVVHQSVAQNSTQKVLS
220 230 240 250 260 270
430 440 450 460 470 480
pF1KE0 FTTTTLDDILKSFSDVSVIRVASGYLLMLAYACLTMLRWDCSKSQGAVGLAGVLLVALSV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FTTTTLDDILKSFSDVSVIRVASGYLLMLAYACLTMLRWDCSKSQGAVGLAGVLLVALSV
280 290 300 310 320 330
490 500 510 520 530 540
pF1KE0 AAGLGLCSLIGISFNAATTQVLPFLALGVGVDDVFLLAHAFSETGQNKRIPFEDRTGECL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AAGLGLCSLIGISFNAATTQVLPFLALGVGVDDVFLLAHAFSETGQNKRIPFEDRTGECL
340 350 360 370 380 390
550 560 570 580 590 600
pF1KE0 KRTGASVALTSISNVTAFFMAALIPIPALRAFSLQAAVVVVFNFAMVLLIFPAILSMDLY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KRTGASVALTSISNVTAFFMAALIPIPALRAFSLQAAVVVVFNFAMVLLIFPAILSMDLY
400 410 420 430 440 450
610 620 630 640 650 660
pF1KE0 RREDRRLDIFCCFTSPCVSRVIQVEPQAYTDTHDNTRYSPPPPYSSHSFAHETQITMQST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RREDRRLDIFCCFTSPCVSRVIQVEPQAYTDTHDNTRYSPPPPYSSHSFAHETQITMQST
460 470 480 490 500 510
670 680 690 700 710 720
pF1KE0 VQLRTEYDPHTHVYYTTAEPRSEISVQPVTVTQDTLSCQSPESTSSTRDLLSQFSDSSLH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VQLRTEYDPHTHVYYTTAEPRSEISVQPVTVTQDTLSCQSPESTSSTRDLLSQFSDSSLH
520 530 540 550 560 570
730 740 750 760 770 780
pF1KE0 CLEPPCTKWTLSSFAEKHYAPFLLKPKAKVVVIFLFLGLLGVSLYGTTRVRDGLDLTDIV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CLEPPCTKWTLSSFAEKHYAPFLLKPKAKVVVIFLFLGLLGVSLYGTTRVRDGLDLTDIV
580 590 600 610 620 630
790 800 810 820 830 840
pF1KE0 PRETREYDFIAAQFKYFSFYNMYIVTQKADYPNIQHLLYDLHRSFSNVKYVMLEENKQLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PRETREYDFIAAQFKYFSFYNMYIVTQKADYPNIQHLLYDLHRSFSNVKYVMLEENKQLP
640 650 660 670 680 690
850 860 870 880 890 900
pF1KE0 KMWLHYFRDWLQGLQDAFDSDWETGKIMPNNYKNGSDDGVLAYKLLVQTGSRDKPIDISQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KMWLHYFRDWLQGLQDAFDSDWETGKIMPNNYKNGSDDGVLAYKLLVQTGSRDKPIDISQ
700 710 720 730 740 750
910 920 930 940 950 960
pF1KE0 LTKQRLVDADGIINPSAFYIYLTAWVSNDPVAYAASQANIRPHRPEWVHDKADYMPETRL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LTKQRLVDADGIINPSAFYIYLTAWVSNDPVAYAASQANIRPHRPEWVHDKADYMPETRL
760 770 780 790 800 810
970 980 990 1000 1010 1020
pF1KE0 RIPAAEPIEYAQFPFYLNGLRDTSDFVEAIEKVRTICSNYTSLGLSSYPNGYPFLFWEQY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RIPAAEPIEYAQFPFYLNGLRDTSDFVEAIEKVRTICSNYTSLGLSSYPNGYPFLFWEQY
820 830 840 850 860 870
1030 1040 1050 1060 1070 1080
pF1KE0 IGLRHWLLLFISVVLACTFLVCAVFLLNPWTAGIIVMVLALMTVELFGMMGLIGIKLSAV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IGLRHWLLLFISVVLACTFLVCAVFLLNPWTAGIIVMVLALMTVELFGMMGLIGIKLSAV
880 890 900 910 920 930
1090 1100 1110 1120 1130 1140
pF1KE0 PVVILIASVGIGVEFTVHVALAFLTAIGDKNRRAVLALEHMFAPVLDGAVSTLLGVLMLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PVVILIASVGIGVEFTVHVALAFLTAIGDKNRRAVLALEHMFAPVLDGAVSTLLGVLMLA
940 950 960 970 980 990
1150 1160 1170 1180 1190 1200
pF1KE0 GSEFDFIVRYFFAVLAILTILGVLNGLVLLPVLLSFFGPYPEVSPANGLNRLPTPSPEPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GSEFDFIVRYFFAVLAILTILGVLNGLVLLPVLLSFFGPYPEVSPANGLNRLPTPSPEPP
1000 1010 1020 1030 1040 1050
1210 1220 1230 1240 1250 1260
pF1KE0 PSVVRFAMPPGHTHSGSDSSDSEYSSQTTVSGLSEELRHYEAQQGAGGPAHQVIVEATEN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PSVVRFAMPPGHTHSGSDSSDSEYSSQTTVSGLSEELRHYEAQQGAGGPAHQVIVEATEN
1060 1070 1080 1090 1100 1110
1270 1280 1290 1300 1310 1320
pF1KE0 PVFAHSTVVHPESRHHPPSNPRQQPHLDSGSLPPGRQGQQPRRDPPREGLWPPPYRPRRD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PVFAHSTVVHPESRHHPPSNPRQQPHLDSGSLPPGRQGQQPRRDPPREGLWPPPYRPRRD
1120 1130 1140 1150 1160 1170
1330 1340 1350 1360 1370 1380
pF1KE0 AFEISTEGHSGPSNRARWGPRGARSHNPRNPASTAMGSSVPGYCQPITTVTASASVTVAV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AFEISTEGHSGPSNRARWGPRGARSHNPRNPASTAMGSSVPGYCQPITTVTASASVTVAV
1180 1190 1200 1210 1220 1230
1390 1400 1410 1420 1430 1440
pF1KE0 HPPPVPGPGRNPRGGLCPGYPETDHGLFEDPHVPFHVRCERRDSKVEVIELQDVECEERP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HPPPVPGPGRNPRGGLCPGYPETDHGLFEDPHVPFHVRCERRDSKVEVIELQDVECEERP
1240 1250 1260 1270 1280 1290
pF1KE0 RGSSSN
::::::
NP_001 RGSSSN
>>NP_001077073 (OMIM: 109400,601309,605462,610828) prote (1296 aa)
initn: 8768 init1: 8768 opt: 8768 Z-score: 5405.4 bits: 1012.6 E(85289): 0
Smith-Waterman score: 8768; 100.0% identity (100.0% similar) in 1296 aa overlap (152-1447:1-1296)
130 140 150 160 170 180
pF1KE0 ETNVEELWVEVGGRVSRELNYTRQKIGEEAMFNPQLMIQTPKEEGANVLTTEALLQHLDS
::::::::::::::::::::::::::::::
NP_001 MFNPQLMIQTPKEEGANVLTTEALLQHLDS
10 20 30
190 200 210 220 230 240
pF1KE0 ALQASRVHVYMYNRQWKLEHLCYKSGELITETGYMDQIIEYLYPCLIITPLDCFWEGAKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ALQASRVHVYMYNRQWKLEHLCYKSGELITETGYMDQIIEYLYPCLIITPLDCFWEGAKL
40 50 60 70 80 90
250 260 270 280 290 300
pF1KE0 QSGTAYLLGKPPLRWTNFDPLEFLEELKKINYQVDSWEEMLNKAEVGHGYMDRPCLNPAD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QSGTAYLLGKPPLRWTNFDPLEFLEELKKINYQVDSWEEMLNKAEVGHGYMDRPCLNPAD
100 110 120 130 140 150
310 320 330 340 350 360
pF1KE0 PDCPATAPNKNSTKPLDMALVLNGGCHGLSRKYMHWQEELIVGGTVKNSTGKLVSAHALQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PDCPATAPNKNSTKPLDMALVLNGGCHGLSRKYMHWQEELIVGGTVKNSTGKLVSAHALQ
160 170 180 190 200 210
370 380 390 400 410 420
pF1KE0 TMFQLMTPKQMYEHFKGYEYVSHINWNEDKAAAILEAWQRTYVEVVHQSVAQNSTQKVLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TMFQLMTPKQMYEHFKGYEYVSHINWNEDKAAAILEAWQRTYVEVVHQSVAQNSTQKVLS
220 230 240 250 260 270
430 440 450 460 470 480
pF1KE0 FTTTTLDDILKSFSDVSVIRVASGYLLMLAYACLTMLRWDCSKSQGAVGLAGVLLVALSV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FTTTTLDDILKSFSDVSVIRVASGYLLMLAYACLTMLRWDCSKSQGAVGLAGVLLVALSV
280 290 300 310 320 330
490 500 510 520 530 540
pF1KE0 AAGLGLCSLIGISFNAATTQVLPFLALGVGVDDVFLLAHAFSETGQNKRIPFEDRTGECL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AAGLGLCSLIGISFNAATTQVLPFLALGVGVDDVFLLAHAFSETGQNKRIPFEDRTGECL
340 350 360 370 380 390
550 560 570 580 590 600
pF1KE0 KRTGASVALTSISNVTAFFMAALIPIPALRAFSLQAAVVVVFNFAMVLLIFPAILSMDLY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KRTGASVALTSISNVTAFFMAALIPIPALRAFSLQAAVVVVFNFAMVLLIFPAILSMDLY
400 410 420 430 440 450
610 620 630 640 650 660
pF1KE0 RREDRRLDIFCCFTSPCVSRVIQVEPQAYTDTHDNTRYSPPPPYSSHSFAHETQITMQST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RREDRRLDIFCCFTSPCVSRVIQVEPQAYTDTHDNTRYSPPPPYSSHSFAHETQITMQST
460 470 480 490 500 510
670 680 690 700 710 720
pF1KE0 VQLRTEYDPHTHVYYTTAEPRSEISVQPVTVTQDTLSCQSPESTSSTRDLLSQFSDSSLH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VQLRTEYDPHTHVYYTTAEPRSEISVQPVTVTQDTLSCQSPESTSSTRDLLSQFSDSSLH
520 530 540 550 560 570
730 740 750 760 770 780
pF1KE0 CLEPPCTKWTLSSFAEKHYAPFLLKPKAKVVVIFLFLGLLGVSLYGTTRVRDGLDLTDIV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CLEPPCTKWTLSSFAEKHYAPFLLKPKAKVVVIFLFLGLLGVSLYGTTRVRDGLDLTDIV
580 590 600 610 620 630
790 800 810 820 830 840
pF1KE0 PRETREYDFIAAQFKYFSFYNMYIVTQKADYPNIQHLLYDLHRSFSNVKYVMLEENKQLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PRETREYDFIAAQFKYFSFYNMYIVTQKADYPNIQHLLYDLHRSFSNVKYVMLEENKQLP
640 650 660 670 680 690
850 860 870 880 890 900
pF1KE0 KMWLHYFRDWLQGLQDAFDSDWETGKIMPNNYKNGSDDGVLAYKLLVQTGSRDKPIDISQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KMWLHYFRDWLQGLQDAFDSDWETGKIMPNNYKNGSDDGVLAYKLLVQTGSRDKPIDISQ
700 710 720 730 740 750
910 920 930 940 950 960
pF1KE0 LTKQRLVDADGIINPSAFYIYLTAWVSNDPVAYAASQANIRPHRPEWVHDKADYMPETRL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LTKQRLVDADGIINPSAFYIYLTAWVSNDPVAYAASQANIRPHRPEWVHDKADYMPETRL
760 770 780 790 800 810
970 980 990 1000 1010 1020
pF1KE0 RIPAAEPIEYAQFPFYLNGLRDTSDFVEAIEKVRTICSNYTSLGLSSYPNGYPFLFWEQY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RIPAAEPIEYAQFPFYLNGLRDTSDFVEAIEKVRTICSNYTSLGLSSYPNGYPFLFWEQY
820 830 840 850 860 870
1030 1040 1050 1060 1070 1080
pF1KE0 IGLRHWLLLFISVVLACTFLVCAVFLLNPWTAGIIVMVLALMTVELFGMMGLIGIKLSAV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IGLRHWLLLFISVVLACTFLVCAVFLLNPWTAGIIVMVLALMTVELFGMMGLIGIKLSAV
880 890 900 910 920 930
1090 1100 1110 1120 1130 1140
pF1KE0 PVVILIASVGIGVEFTVHVALAFLTAIGDKNRRAVLALEHMFAPVLDGAVSTLLGVLMLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PVVILIASVGIGVEFTVHVALAFLTAIGDKNRRAVLALEHMFAPVLDGAVSTLLGVLMLA
940 950 960 970 980 990
1150 1160 1170 1180 1190 1200
pF1KE0 GSEFDFIVRYFFAVLAILTILGVLNGLVLLPVLLSFFGPYPEVSPANGLNRLPTPSPEPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GSEFDFIVRYFFAVLAILTILGVLNGLVLLPVLLSFFGPYPEVSPANGLNRLPTPSPEPP
1000 1010 1020 1030 1040 1050
1210 1220 1230 1240 1250 1260
pF1KE0 PSVVRFAMPPGHTHSGSDSSDSEYSSQTTVSGLSEELRHYEAQQGAGGPAHQVIVEATEN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PSVVRFAMPPGHTHSGSDSSDSEYSSQTTVSGLSEELRHYEAQQGAGGPAHQVIVEATEN
1060 1070 1080 1090 1100 1110
1270 1280 1290 1300 1310 1320
pF1KE0 PVFAHSTVVHPESRHHPPSNPRQQPHLDSGSLPPGRQGQQPRRDPPREGLWPPPYRPRRD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PVFAHSTVVHPESRHHPPSNPRQQPHLDSGSLPPGRQGQQPRRDPPREGLWPPPYRPRRD
1120 1130 1140 1150 1160 1170
1330 1340 1350 1360 1370 1380
pF1KE0 AFEISTEGHSGPSNRARWGPRGARSHNPRNPASTAMGSSVPGYCQPITTVTASASVTVAV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AFEISTEGHSGPSNRARWGPRGARSHNPRNPASTAMGSSVPGYCQPITTVTASASVTVAV
1180 1190 1200 1210 1220 1230
1390 1400 1410 1420 1430 1440
pF1KE0 HPPPVPGPGRNPRGGLCPGYPETDHGLFEDPHVPFHVRCERRDSKVEVIELQDVECEERP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HPPPVPGPGRNPRGGLCPGYPETDHGLFEDPHVPFHVRCERRDSKVEVIELQDVECEERP
1240 1250 1260 1270 1280 1290
pF1KE0 RGSSSN
::::::
NP_001 RGSSSN
>>NP_001077074 (OMIM: 109400,601309,605462,610828) prote (1296 aa)
initn: 8768 init1: 8768 opt: 8768 Z-score: 5405.4 bits: 1012.6 E(85289): 0
Smith-Waterman score: 8768; 100.0% identity (100.0% similar) in 1296 aa overlap (152-1447:1-1296)
130 140 150 160 170 180
pF1KE0 ETNVEELWVEVGGRVSRELNYTRQKIGEEAMFNPQLMIQTPKEEGANVLTTEALLQHLDS
::::::::::::::::::::::::::::::
NP_001 MFNPQLMIQTPKEEGANVLTTEALLQHLDS
10 20 30
190 200 210 220 230 240
pF1KE0 ALQASRVHVYMYNRQWKLEHLCYKSGELITETGYMDQIIEYLYPCLIITPLDCFWEGAKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ALQASRVHVYMYNRQWKLEHLCYKSGELITETGYMDQIIEYLYPCLIITPLDCFWEGAKL
40 50 60 70 80 90
250 260 270 280 290 300
pF1KE0 QSGTAYLLGKPPLRWTNFDPLEFLEELKKINYQVDSWEEMLNKAEVGHGYMDRPCLNPAD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QSGTAYLLGKPPLRWTNFDPLEFLEELKKINYQVDSWEEMLNKAEVGHGYMDRPCLNPAD
100 110 120 130 140 150
310 320 330 340 350 360
pF1KE0 PDCPATAPNKNSTKPLDMALVLNGGCHGLSRKYMHWQEELIVGGTVKNSTGKLVSAHALQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PDCPATAPNKNSTKPLDMALVLNGGCHGLSRKYMHWQEELIVGGTVKNSTGKLVSAHALQ
160 170 180 190 200 210
370 380 390 400 410 420
pF1KE0 TMFQLMTPKQMYEHFKGYEYVSHINWNEDKAAAILEAWQRTYVEVVHQSVAQNSTQKVLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TMFQLMTPKQMYEHFKGYEYVSHINWNEDKAAAILEAWQRTYVEVVHQSVAQNSTQKVLS
220 230 240 250 260 270
430 440 450 460 470 480
pF1KE0 FTTTTLDDILKSFSDVSVIRVASGYLLMLAYACLTMLRWDCSKSQGAVGLAGVLLVALSV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FTTTTLDDILKSFSDVSVIRVASGYLLMLAYACLTMLRWDCSKSQGAVGLAGVLLVALSV
280 290 300 310 320 330
490 500 510 520 530 540
pF1KE0 AAGLGLCSLIGISFNAATTQVLPFLALGVGVDDVFLLAHAFSETGQNKRIPFEDRTGECL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AAGLGLCSLIGISFNAATTQVLPFLALGVGVDDVFLLAHAFSETGQNKRIPFEDRTGECL
340 350 360 370 380 390
550 560 570 580 590 600
pF1KE0 KRTGASVALTSISNVTAFFMAALIPIPALRAFSLQAAVVVVFNFAMVLLIFPAILSMDLY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KRTGASVALTSISNVTAFFMAALIPIPALRAFSLQAAVVVVFNFAMVLLIFPAILSMDLY
400 410 420 430 440 450
610 620 630 640 650 660
pF1KE0 RREDRRLDIFCCFTSPCVSRVIQVEPQAYTDTHDNTRYSPPPPYSSHSFAHETQITMQST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RREDRRLDIFCCFTSPCVSRVIQVEPQAYTDTHDNTRYSPPPPYSSHSFAHETQITMQST
460 470 480 490 500 510
670 680 690 700 710 720
pF1KE0 VQLRTEYDPHTHVYYTTAEPRSEISVQPVTVTQDTLSCQSPESTSSTRDLLSQFSDSSLH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VQLRTEYDPHTHVYYTTAEPRSEISVQPVTVTQDTLSCQSPESTSSTRDLLSQFSDSSLH
520 530 540 550 560 570
730 740 750 760 770 780
pF1KE0 CLEPPCTKWTLSSFAEKHYAPFLLKPKAKVVVIFLFLGLLGVSLYGTTRVRDGLDLTDIV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CLEPPCTKWTLSSFAEKHYAPFLLKPKAKVVVIFLFLGLLGVSLYGTTRVRDGLDLTDIV
580 590 600 610 620 630
790 800 810 820 830 840
pF1KE0 PRETREYDFIAAQFKYFSFYNMYIVTQKADYPNIQHLLYDLHRSFSNVKYVMLEENKQLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PRETREYDFIAAQFKYFSFYNMYIVTQKADYPNIQHLLYDLHRSFSNVKYVMLEENKQLP
640 650 660 670 680 690
850 860 870 880 890 900
pF1KE0 KMWLHYFRDWLQGLQDAFDSDWETGKIMPNNYKNGSDDGVLAYKLLVQTGSRDKPIDISQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KMWLHYFRDWLQGLQDAFDSDWETGKIMPNNYKNGSDDGVLAYKLLVQTGSRDKPIDISQ
700 710 720 730 740 750
910 920 930 940 950 960
pF1KE0 LTKQRLVDADGIINPSAFYIYLTAWVSNDPVAYAASQANIRPHRPEWVHDKADYMPETRL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LTKQRLVDADGIINPSAFYIYLTAWVSNDPVAYAASQANIRPHRPEWVHDKADYMPETRL
760 770 780 790 800 810
970 980 990 1000 1010 1020
pF1KE0 RIPAAEPIEYAQFPFYLNGLRDTSDFVEAIEKVRTICSNYTSLGLSSYPNGYPFLFWEQY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RIPAAEPIEYAQFPFYLNGLRDTSDFVEAIEKVRTICSNYTSLGLSSYPNGYPFLFWEQY
820 830 840 850 860 870
1030 1040 1050 1060 1070 1080
pF1KE0 IGLRHWLLLFISVVLACTFLVCAVFLLNPWTAGIIVMVLALMTVELFGMMGLIGIKLSAV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IGLRHWLLLFISVVLACTFLVCAVFLLNPWTAGIIVMVLALMTVELFGMMGLIGIKLSAV
880 890 900 910 920 930
1090 1100 1110 1120 1130 1140
pF1KE0 PVVILIASVGIGVEFTVHVALAFLTAIGDKNRRAVLALEHMFAPVLDGAVSTLLGVLMLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PVVILIASVGIGVEFTVHVALAFLTAIGDKNRRAVLALEHMFAPVLDGAVSTLLGVLMLA
940 950 960 970 980 990
1150 1160 1170 1180 1190 1200
pF1KE0 GSEFDFIVRYFFAVLAILTILGVLNGLVLLPVLLSFFGPYPEVSPANGLNRLPTPSPEPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GSEFDFIVRYFFAVLAILTILGVLNGLVLLPVLLSFFGPYPEVSPANGLNRLPTPSPEPP
1000 1010 1020 1030 1040 1050
1210 1220 1230 1240 1250 1260
pF1KE0 PSVVRFAMPPGHTHSGSDSSDSEYSSQTTVSGLSEELRHYEAQQGAGGPAHQVIVEATEN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PSVVRFAMPPGHTHSGSDSSDSEYSSQTTVSGLSEELRHYEAQQGAGGPAHQVIVEATEN
1060 1070 1080 1090 1100 1110
1270 1280 1290 1300 1310 1320
pF1KE0 PVFAHSTVVHPESRHHPPSNPRQQPHLDSGSLPPGRQGQQPRRDPPREGLWPPPYRPRRD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PVFAHSTVVHPESRHHPPSNPRQQPHLDSGSLPPGRQGQQPRRDPPREGLWPPPYRPRRD
1120 1130 1140 1150 1160 1170
1330 1340 1350 1360 1370 1380
pF1KE0 AFEISTEGHSGPSNRARWGPRGARSHNPRNPASTAMGSSVPGYCQPITTVTASASVTVAV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AFEISTEGHSGPSNRARWGPRGARSHNPRNPASTAMGSSVPGYCQPITTVTASASVTVAV
1180 1190 1200 1210 1220 1230
1390 1400 1410 1420 1430 1440
pF1KE0 HPPPVPGPGRNPRGGLCPGYPETDHGLFEDPHVPFHVRCERRDSKVEVIELQDVECEERP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HPPPVPGPGRNPRGGLCPGYPETDHGLFEDPHVPFHVRCERRDSKVEVIELQDVECEERP
1240 1250 1260 1270 1280 1290
pF1KE0 RGSSSN
::::::
NP_001 RGSSSN
>>NP_001077076 (OMIM: 109400,601309,605462,610828) prote (1296 aa)
initn: 8768 init1: 8768 opt: 8768 Z-score: 5405.4 bits: 1012.6 E(85289): 0
Smith-Waterman score: 8768; 100.0% identity (100.0% similar) in 1296 aa overlap (152-1447:1-1296)
130 140 150 160 170 180
pF1KE0 ETNVEELWVEVGGRVSRELNYTRQKIGEEAMFNPQLMIQTPKEEGANVLTTEALLQHLDS
::::::::::::::::::::::::::::::
NP_001 MFNPQLMIQTPKEEGANVLTTEALLQHLDS
10 20 30
190 200 210 220 230 240
pF1KE0 ALQASRVHVYMYNRQWKLEHLCYKSGELITETGYMDQIIEYLYPCLIITPLDCFWEGAKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ALQASRVHVYMYNRQWKLEHLCYKSGELITETGYMDQIIEYLYPCLIITPLDCFWEGAKL
40 50 60 70 80 90
250 260 270 280 290 300
pF1KE0 QSGTAYLLGKPPLRWTNFDPLEFLEELKKINYQVDSWEEMLNKAEVGHGYMDRPCLNPAD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QSGTAYLLGKPPLRWTNFDPLEFLEELKKINYQVDSWEEMLNKAEVGHGYMDRPCLNPAD
100 110 120 130 140 150
310 320 330 340 350 360
pF1KE0 PDCPATAPNKNSTKPLDMALVLNGGCHGLSRKYMHWQEELIVGGTVKNSTGKLVSAHALQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PDCPATAPNKNSTKPLDMALVLNGGCHGLSRKYMHWQEELIVGGTVKNSTGKLVSAHALQ
160 170 180 190 200 210
370 380 390 400 410 420
pF1KE0 TMFQLMTPKQMYEHFKGYEYVSHINWNEDKAAAILEAWQRTYVEVVHQSVAQNSTQKVLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TMFQLMTPKQMYEHFKGYEYVSHINWNEDKAAAILEAWQRTYVEVVHQSVAQNSTQKVLS
220 230 240 250 260 270
430 440 450 460 470 480
pF1KE0 FTTTTLDDILKSFSDVSVIRVASGYLLMLAYACLTMLRWDCSKSQGAVGLAGVLLVALSV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FTTTTLDDILKSFSDVSVIRVASGYLLMLAYACLTMLRWDCSKSQGAVGLAGVLLVALSV
280 290 300 310 320 330
490 500 510 520 530 540
pF1KE0 AAGLGLCSLIGISFNAATTQVLPFLALGVGVDDVFLLAHAFSETGQNKRIPFEDRTGECL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AAGLGLCSLIGISFNAATTQVLPFLALGVGVDDVFLLAHAFSETGQNKRIPFEDRTGECL
340 350 360 370 380 390
550 560 570 580 590 600
pF1KE0 KRTGASVALTSISNVTAFFMAALIPIPALRAFSLQAAVVVVFNFAMVLLIFPAILSMDLY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KRTGASVALTSISNVTAFFMAALIPIPALRAFSLQAAVVVVFNFAMVLLIFPAILSMDLY
400 410 420 430 440 450
610 620 630 640 650 660
pF1KE0 RREDRRLDIFCCFTSPCVSRVIQVEPQAYTDTHDNTRYSPPPPYSSHSFAHETQITMQST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RREDRRLDIFCCFTSPCVSRVIQVEPQAYTDTHDNTRYSPPPPYSSHSFAHETQITMQST
460 470 480 490 500 510
670 680 690 700 710 720
pF1KE0 VQLRTEYDPHTHVYYTTAEPRSEISVQPVTVTQDTLSCQSPESTSSTRDLLSQFSDSSLH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VQLRTEYDPHTHVYYTTAEPRSEISVQPVTVTQDTLSCQSPESTSSTRDLLSQFSDSSLH
520 530 540 550 560 570
730 740 750 760 770 780
pF1KE0 CLEPPCTKWTLSSFAEKHYAPFLLKPKAKVVVIFLFLGLLGVSLYGTTRVRDGLDLTDIV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CLEPPCTKWTLSSFAEKHYAPFLLKPKAKVVVIFLFLGLLGVSLYGTTRVRDGLDLTDIV
580 590 600 610 620 630
790 800 810 820 830 840
pF1KE0 PRETREYDFIAAQFKYFSFYNMYIVTQKADYPNIQHLLYDLHRSFSNVKYVMLEENKQLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PRETREYDFIAAQFKYFSFYNMYIVTQKADYPNIQHLLYDLHRSFSNVKYVMLEENKQLP
640 650 660 670 680 690
850 860 870 880 890 900
pF1KE0 KMWLHYFRDWLQGLQDAFDSDWETGKIMPNNYKNGSDDGVLAYKLLVQTGSRDKPIDISQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KMWLHYFRDWLQGLQDAFDSDWETGKIMPNNYKNGSDDGVLAYKLLVQTGSRDKPIDISQ
700 710 720 730 740 750
910 920 930 940 950 960
pF1KE0 LTKQRLVDADGIINPSAFYIYLTAWVSNDPVAYAASQANIRPHRPEWVHDKADYMPETRL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LTKQRLVDADGIINPSAFYIYLTAWVSNDPVAYAASQANIRPHRPEWVHDKADYMPETRL
760 770 780 790 800 810
970 980 990 1000 1010 1020
pF1KE0 RIPAAEPIEYAQFPFYLNGLRDTSDFVEAIEKVRTICSNYTSLGLSSYPNGYPFLFWEQY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RIPAAEPIEYAQFPFYLNGLRDTSDFVEAIEKVRTICSNYTSLGLSSYPNGYPFLFWEQY
820 830 840 850 860 870
1030 1040 1050 1060 1070 1080
pF1KE0 IGLRHWLLLFISVVLACTFLVCAVFLLNPWTAGIIVMVLALMTVELFGMMGLIGIKLSAV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IGLRHWLLLFISVVLACTFLVCAVFLLNPWTAGIIVMVLALMTVELFGMMGLIGIKLSAV
880 890 900 910 920 930
1090 1100 1110 1120 1130 1140
pF1KE0 PVVILIASVGIGVEFTVHVALAFLTAIGDKNRRAVLALEHMFAPVLDGAVSTLLGVLMLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PVVILIASVGIGVEFTVHVALAFLTAIGDKNRRAVLALEHMFAPVLDGAVSTLLGVLMLA
940 950 960 970 980 990
1150 1160 1170 1180 1190 1200
pF1KE0 GSEFDFIVRYFFAVLAILTILGVLNGLVLLPVLLSFFGPYPEVSPANGLNRLPTPSPEPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GSEFDFIVRYFFAVLAILTILGVLNGLVLLPVLLSFFGPYPEVSPANGLNRLPTPSPEPP
1000 1010 1020 1030 1040 1050
1210 1220 1230 1240 1250 1260
pF1KE0 PSVVRFAMPPGHTHSGSDSSDSEYSSQTTVSGLSEELRHYEAQQGAGGPAHQVIVEATEN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PSVVRFAMPPGHTHSGSDSSDSEYSSQTTVSGLSEELRHYEAQQGAGGPAHQVIVEATEN
1060 1070 1080 1090 1100 1110
1270 1280 1290 1300 1310 1320
pF1KE0 PVFAHSTVVHPESRHHPPSNPRQQPHLDSGSLPPGRQGQQPRRDPPREGLWPPPYRPRRD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PVFAHSTVVHPESRHHPPSNPRQQPHLDSGSLPPGRQGQQPRRDPPREGLWPPPYRPRRD
1120 1130 1140 1150 1160 1170
1330 1340 1350 1360 1370 1380
pF1KE0 AFEISTEGHSGPSNRARWGPRGARSHNPRNPASTAMGSSVPGYCQPITTVTASASVTVAV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AFEISTEGHSGPSNRARWGPRGARSHNPRNPASTAMGSSVPGYCQPITTVTASASVTVAV
1180 1190 1200 1210 1220 1230
1390 1400 1410 1420 1430 1440
pF1KE0 HPPPVPGPGRNPRGGLCPGYPETDHGLFEDPHVPFHVRCERRDSKVEVIELQDVECEERP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HPPPVPGPGRNPRGGLCPGYPETDHGLFEDPHVPFHVRCERRDSKVEVIELQDVECEERP
1240 1250 1260 1270 1280 1290
pF1KE0 RGSSSN
::::::
NP_001 RGSSSN
>>NP_001159764 (OMIM: 109400,155255,603673,605462) prote (1146 aa)
initn: 3584 init1: 1216 opt: 2010 Z-score: 1249.5 bits: 243.4 E(85289): 7.4e-63
Smith-Waterman score: 4355; 56.3% identity (81.9% similar) in 1158 aa overlap (53-1203:12-1135)
30 40 50 60 70 80
pF1KE0 APGRPAGGGRRRRTGGLRRAAAPDRDYLHRPSYCDAA-FALEQISKGKATGRKAPLWLRA
::: : : :: :. ::::::::
NP_001 MTRSPPLRELPPSYTPPARTAAPQILAGSL---KAPLWLRA
10 20 30
90 100 110 120 130 140
pF1KE0 KFQRLLFKLGCYIQKNCGKFLVVGLLIFGAFAVGLKAANLETNVEELWVEVGGRVSRELN
:: :::.::: ::..::: : .::: :::.:.::. : .:::.:.::::::.:::.::.
NP_001 YFQGLLFSLGCGIQRHCGKVLFLGLLAFGALALGLRMAIIETNLEQLWVEVGSRVSQELH
40 50 60 70 80 90
150 160 170 180 190 200
pF1KE0 YTRQKIGEEAMFNPQLMIQTPKEEGANVLTTEALLQHLDSALQASRVHVYMYNRQWKLEH
::..:.:::: .. :..::: ..:: :.:: ::: ::..:: ::.:.: .:...: :..
NP_001 YTKEKLGEEAAYTSQMLIQTARQEGENILTPEALGLHLQAALTASKVQVSLYGKSWDLNK
100 110 120 130 140 150
210 220 230 240 250 260
pF1KE0 LCYKSGELITETGYMDQIIEYLYPCLIITPLDCFWEGAKLQSGTAYLLGKPPLRWTNFDP
.::::: . :.:.....:: :.::.:.:::::::::::::.:.::: :.: ..:::.::
NP_001 ICYKSGVPLIENGMIERMIEKLFPCVILTPLDCFWEGAKLQGGSAYLPGRPDIQWTNLDP
160 170 180 190 200 210
270 280 290 300 310 320
pF1KE0 LEFLEELKKINYQVDSWEEMLNKAEVGHGYMDRPCLNPADPDCPATAPNKNSTKPLDMAL
..:::: . ......:.:.::.::..:. ::::.: : :: .:::..: . ..:
NP_001 EQLLEELGPFA-SLEGFRELLDKAQVGQAYVGRPCLHPDDLHCPPSAPNHHSRQAPNVAH
220 230 240 250 260 270
330 340 350 360 370 380
pF1KE0 VLNGGCHGLSRKYMHWQEELIVGGTVKNSTGKLVSAHALQTMFQLMTPKQMYEHFKGYEY
:.:::::.:.:.:::::::..:: ... :.:. :.:::. : ::.:.:.::::.: .:
NP_001 ELSGGCHGFSHKFMHWQEELLLGGMARDPQGELLRAEALQSTFLLMSPRQLYEHFRG-DY
280 290 300 310 320 330
390 400 410 420 430 440
pF1KE0 VSH-INWNEDKAAAILEAWQRTYVEVVHQSVAQNSTQKVLSFTTTTLDDILKSFSDVSVI
.: :.:.:..:...:.:::: .:....... .:..:.. .:..:::::::..::.::.
NP_001 QTHDIGWSEEQASTVLQAWQRRFVQLAQEALPENASQQIHAFSSTTLDDILHAFSEVSAA
340 350 360 370 380 390
450 460 470 480 490 500
pF1KE0 RVASGYLLMLAYACLTMLRWDCSKSQGAVGLAGVLLVALSVAAGLGLCSLIGISFNAATT
::..::::::::::.:::::::..:::.:::::::::::.::.:::::.:.::.::::::
NP_001 RVVGGYLLMLAYACVTMLRWDCAQSQGSVGLAGVLLVALAVASGLGLCALLGITFNAATT
400 410 420 430 440 450
510 520 530 540 550 560
pF1KE0 QVLPFLALGVGVDDVFLLAHAFSETGQNKRIPFEDRTGECLKRTGASVALTSISNVTAFF
:::::::::.::::::::::::.:. . :...: ::::.:::.::.::::.:..::.
NP_001 QVLPFLALGIGVDDVFLLAHAFTEALPG--TPLQERMGECLQRTGTSVVLTSINNMAAFL
460 470 480 490 500 510
570 580 590 600 610 620
pF1KE0 MAALIPIPALRAFSLQAAVVVVFNFAMVLLIFPAILSMDLYRREDRRLDIFCCFTSPCVS
::::.:::::::::::::.:: .:. :.:.::::::.:: ::. .:::..:::.::: .
NP_001 MAALVPIPALRAFSLQAAIVVGCTFVAVMLVFPAILSLDLRRRHCQRLDVLCCFSSPCSA
520 530 540 550 560 570
630 640 650 660 670 680
pF1KE0 RVIQVEPQAYTDTHDNTRYSPPPPYSSHSFAHETQITMQSTVQLRTEYDPHTHVYYTTAE
.:::. :: . :.: : . .:: : .::: :. . .. :
NP_001 QVIQILPQ---ELGDGTV-----PVG---IAHLT-----ATVQAFTHCEASSQHVVTILP
580 590 600 610
690 700 710 720 730
pF1KE0 PRSEISVQPVTVTQDTLSCQSPESTSSTRDLLSQFSDSSLH--CLEPPCTKWTLSSFAEK
:.... : .: :. . .::::::.: .. . : ::..:.:. ::.
NP_001 PQAHLVPPP----SDPLGSELFSPGGSTRDLLGQEEETRQKAACKSLPCARWNLAHFARY
620 630 640 650 660 670
740 750 760 770 780 790
pF1KE0 HYAPFLLKPKAKVVVIFLFLGLLGVSLYGTTRVRDGLDLTDIVPRETREYDFIAAQFKYF
..::.::. .::..:. :: .:::.::::.: :.::: :::.::: :.:. :..::..::
NP_001 QFAPLLLQSHAKAIVLVLFGALLGLSLYGATLVQDGLALTDVVPRGTKEHAFLSAQLRYF
680 690 700 710 720 730
800 810 820 830 840 850
pF1KE0 SFYNMYIVTQKA-DYPNIQHLLYDLHRSFSNVKYVMLEENKQLPKMWLHYFRDWLQGLQD
:.:.. .::: . :: . :. :.:::. ::..: :. : :. ::::.:.::::.:
NP_001 SLYEVALVTQGGFDYAHSQRALFDLHQRFSSLKAVLPPPATQAPRTWLHYYRNWLQGIQA
740 750 760 770 780 790
860 870 880 890 900 910
pF1KE0 AFDSDWETGKIMPNNYKNGSDDGVLAYKLLVQTGSRDKPIDISQLTKQRLVDADGIINPS
:::.:: .:.: ..:.:::.::.::::::.:::. ..:.:.:::: ..::: .:.: :
NP_001 AFDQDWASGRITRHSYRNGSEDGALAYKLLIQTGDAQEPLDFSQLTTRKLVDREGLIPPE
800 810 820 830 840 850
920 930 940 950 960 970
pF1KE0 AFYIYLTAWVSNDPVAYAASQANIRPHRPEWVHDKADYMPETRLRIPAAEPIEYAQFPFY
::. ::.:::.::.. ::::::. : :::.::: : :. :::: :.:.:.:::::
NP_001 LFYMGLTVWVSSDPLGLAASQANFYPPPPEWLHDKYDTTGEN-LRIPPAQPLEFAQFPFL
860 870 880 890 900 910
980 990 1000 1010 1020 1030
pF1KE0 LNGLRDTSDFVEAIEKVRTICSNYTSLGLSSYPNGYPFLFWEQYIGLRHWLLLFISVVLA
: ::. :.::::::: .:. :.. . :. .::.: ::::::::.:::. .:: . ..:.
NP_001 LRGLQKTADFVEAIEGARAACAEAGQAGVHAYPSGSPFLFWEQYLGLRRCFLLAVCILLV
920 930 940 950 960 970
1040 1050 1060 1070 1080 1090
pF1KE0 CTFLVCAVFLLNPWTAGIIVMVLALMTVELFGMMGLIGIKLSAVPVVILIASVGIGVEFT
:::::::..::::::::.::.:::.:::::::.::..::::::.:::::.::::::::::
NP_001 CTFLVCALLLLNPWTAGLIVLVLAMMTVELFGIMGFLGIKLSAIPVVILVASVGIGVEFT
980 990 1000 1010 1020 1030
1100 1110 1120 1130 1140 1150
pF1KE0 VHVALAFLTAIGDKNRRAVLALEHMFAPVLDGAVSTLLGVLMLAGSEFDFIVRYFFAVLA
:::::.:::. :..: ::. :::: :::: :::.:::::.::::::.::::::::::.:.
NP_001 VHVALGFLTTQGSRNLRAAHALEHTFAPVTDGAISTLLGLLMLAGSHFDFIVRYFFAALT
1040 1050 1060 1070 1080 1090
1160 1170 1180 1190 1200 1210
pF1KE0 ILTILGVLNGLVLLPVLLSFFGPYPEVSPANGLNRLPTPSPE--PPPSVVRFAMPPGHTH
.::.::.:.::::::::::..:: ::: .. ::: ::.
NP_001 VLTLLGLLHGLVLLPVLLSILGPPPEVI------QMYKESPEILSPPAPQGGGLRPEEI
1100 1110 1120 1130 1140
1220 1230 1240 1250 1260 1270
pF1KE0 SGSDSSDSEYSSQTTVSGLSEELRHYEAQQGAGGPAHQVIVEATENPVFAHSTVVHPESR
>>NP_003729 (OMIM: 109400,155255,603673,605462) protein (1203 aa)
initn: 3662 init1: 1216 opt: 2010 Z-score: 1249.2 bits: 243.5 E(85289): 7.6e-63
Smith-Waterman score: 4357; 55.5% identity (81.0% similar) in 1187 aa overlap (53-1232:12-1159)
30 40 50 60 70 80
pF1KE0 APGRPAGGGRRRRTGGLRRAAAPDRDYLHRPSYCDAA-FALEQISKGKATGRKAPLWLRA
::: : : :: :. ::::::::
NP_003 MTRSPPLRELPPSYTPPARTAAPQILAGSL---KAPLWLRA
10 20 30
90 100 110 120 130 140
pF1KE0 KFQRLLFKLGCYIQKNCGKFLVVGLLIFGAFAVGLKAANLETNVEELWVEVGGRVSRELN
:: :::.::: ::..::: : .::: :::.:.::. : .:::.:.::::::.:::.::.
NP_003 YFQGLLFSLGCGIQRHCGKVLFLGLLAFGALALGLRMAIIETNLEQLWVEVGSRVSQELH
40 50 60 70 80 90
150 160 170 180 190 200
pF1KE0 YTRQKIGEEAMFNPQLMIQTPKEEGANVLTTEALLQHLDSALQASRVHVYMYNRQWKLEH
::..:.:::: .. :..::: ..:: :.:: ::: ::..:: ::.:.: .:...: :..
NP_003 YTKEKLGEEAAYTSQMLIQTARQEGENILTPEALGLHLQAALTASKVQVSLYGKSWDLNK
100 110 120 130 140 150
210 220 230 240 250 260
pF1KE0 LCYKSGELITETGYMDQIIEYLYPCLIITPLDCFWEGAKLQSGTAYLLGKPPLRWTNFDP
.::::: . :.:.....:: :.::.:.:::::::::::::.:.::: :.: ..:::.::
NP_003 ICYKSGVPLIENGMIERMIEKLFPCVILTPLDCFWEGAKLQGGSAYLPGRPDIQWTNLDP
160 170 180 190 200 210
270 280 290 300 310 320
pF1KE0 LEFLEELKKINYQVDSWEEMLNKAEVGHGYMDRPCLNPADPDCPATAPNKNSTKPLDMAL
..:::: . ......:.:.::.::..:. ::::.: : :: .:::..: . ..:
NP_003 EQLLEELGPFA-SLEGFRELLDKAQVGQAYVGRPCLHPDDLHCPPSAPNHHSRQAPNVAH
220 230 240 250 260 270
330 340 350 360 370 380
pF1KE0 VLNGGCHGLSRKYMHWQEELIVGGTVKNSTGKLVSAHALQTMFQLMTPKQMYEHFKGYEY
:.:::::.:.:.:::::::..:: ... :.:. :.:::. : ::.:.:.::::.: .:
NP_003 ELSGGCHGFSHKFMHWQEELLLGGMARDPQGELLRAEALQSTFLLMSPRQLYEHFRG-DY
280 290 300 310 320 330
390 400 410 420 430 440
pF1KE0 VSH-INWNEDKAAAILEAWQRTYVEVVHQSVAQNSTQKVLSFTTTTLDDILKSFSDVSVI
.: :.:.:..:...:.:::: .:....... .:..:.. .:..:::::::..::.::.
NP_003 QTHDIGWSEEQASTVLQAWQRRFVQLAQEALPENASQQIHAFSSTTLDDILHAFSEVSAA
340 350 360 370 380 390
450 460 470 480 490 500
pF1KE0 RVASGYLLMLAYACLTMLRWDCSKSQGAVGLAGVLLVALSVAAGLGLCSLIGISFNAATT
::..::::::::::.:::::::..:::.:::::::::::.::.:::::.:.::.::::::
NP_003 RVVGGYLLMLAYACVTMLRWDCAQSQGSVGLAGVLLVALAVASGLGLCALLGITFNAATT
400 410 420 430 440 450
510 520 530 540 550 560
pF1KE0 QVLPFLALGVGVDDVFLLAHAFSETGQNKRIPFEDRTGECLKRTGASVALTSISNVTAFF
:::::::::.::::::::::::.:. . :...: ::::.:::.::.::::.:..::.
NP_003 QVLPFLALGIGVDDVFLLAHAFTEALPGT--PLQERMGECLQRTGTSVVLTSINNMAAFL
460 470 480 490 500 510
570 580 590 600 610 620
pF1KE0 MAALIPIPALRAFSLQAAVVVVFNFAMVLLIFPAILSMDLYRREDRRLDIFCCFTSPCVS
::::.:::::::::::::.:: .:. :.:.::::::.:: ::. .:::..:::.::: .
NP_003 MAALVPIPALRAFSLQAAIVVGCTFVAVMLVFPAILSLDLRRRHCQRLDVLCCFSSPCSA
520 530 540 550 560 570
630 640 650 660 670 680
pF1KE0 RVIQVEPQAYTDTHDNTRYSPPPPYSSHSFAHETQITMQSTVQLRTEYDPHTHVYYTTAE
.:::. :: . :.: : . .:: : .::: :. . .. :
NP_003 QVIQILPQ---ELGDGT-----VPVG---IAHLT-----ATVQAFTHCEASSQHVVTILP
580 590 600 610
690 700 710 720 730
pF1KE0 PRSEISVQPVTVTQDTLSCQSPESTSSTRDLLSQFSDSSLH--CLEPPCTKWTLSSFAEK
:.... : .: :. . .::::::.: .. . : ::..:.:. ::.
NP_003 PQAHLVPPP----SDPLGSELFSPGGSTRDLLGQEEETRQKAACKSLPCARWNLAHFARY
620 630 640 650 660 670
740 750 760 770 780 790
pF1KE0 HYAPFLLKPKAKVVVIFLFLGLLGVSLYGTTRVRDGLDLTDIVPRETREYDFIAAQFKYF
..::.::. .::..:. :: .:::.::::.: :.::: :::.::: :.:. :..::..::
NP_003 QFAPLLLQSHAKAIVLVLFGALLGLSLYGATLVQDGLALTDVVPRGTKEHAFLSAQLRYF
680 690 700 710 720 730
800 810 820 830 840 850
pF1KE0 SFYNMYIVTQKA-DYPNIQHLLYDLHRSFSNVKYVMLEENKQLPKMWLHYFRDWLQGLQD
:.:.. .::: . :: . :. :.:::. ::..: :. : :. ::::.:.::::.:
NP_003 SLYEVALVTQGGFDYAHSQRALFDLHQRFSSLKAVLPPPATQAPRTWLHYYRNWLQGIQA
740 750 760 770 780 790
860 870 880 890 900 910
pF1KE0 AFDSDWETGKIMPNNYKNGSDDGVLAYKLLVQTGSRDKPIDISQLTKQRLVDADGIINPS
:::.:: .:.: ..:.:::.::.::::::.:::. ..:.:.:::: ..::: .:.: :
NP_003 AFDQDWASGRITRHSYRNGSEDGALAYKLLIQTGDAQEPLDFSQLTTRKLVDREGLIPPE
800 810 820 830 840 850
920 930 940 950 960 970
pF1KE0 AFYIYLTAWVSNDPVAYAASQANIRPHRPEWVHDKADYMPETRLRIPAAEPIEYAQFPFY
::. ::.:::.::.. ::::::. : :::.::: : :. :::: :.:.:.:::::
NP_003 LFYMGLTVWVSSDPLGLAASQANFYPPPPEWLHDKYDTTGEN-LRIPPAQPLEFAQFPFL
860 870 880 890 900 910
980 990 1000 1010 1020 1030
pF1KE0 LNGLRDTSDFVEAIEKVRTICSNYTSLGLSSYPNGYPFLFWEQYIGLRHWLLLFISVVLA
: ::. :.::::::: .:. :.. . :. .::.: ::::::::.:::. .:: . ..:.
NP_003 LRGLQKTADFVEAIEGARAACAEAGQAGVHAYPSGSPFLFWEQYLGLRRCFLLAVCILLV
920 930 940 950 960 970
1040 1050 1060 1070 1080 1090
pF1KE0 CTFLVCAVFLLNPWTAGIIVMVLALMTVELFGMMGLIGIKLSAVPVVILIASVGIGVEFT
:::::::..::::::::.::.:::.:::::::.::..::::::.:::::.::::::::::
NP_003 CTFLVCALLLLNPWTAGLIVLVLAMMTVELFGIMGFLGIKLSAIPVVILVASVGIGVEFT
980 990 1000 1010 1020 1030
1100 1110 1120 1130 1140 1150
pF1KE0 VHVALAFLTAIGDKNRRAVLALEHMFAPVLDGAVSTLLGVLMLAGSEFDFIVRYFFAVLA
:::::.:::. :..: ::. :::: :::: :::.:::::.::::::.::::::::::.:.
NP_003 VHVALGFLTTQGSRNLRAAHALEHTFAPVTDGAISTLLGLLMLAGSHFDFIVRYFFAALT
1040 1050 1060 1070 1080 1090
1160 1170 1180 1190 1200 1210
pF1KE0 ILTILGVLNGLVLLPVLLSFFGPYPEVSPANGLNRLPTPSPE--PPPSVVRFAMPPGHTH
.::.::.:.::::::::::..:: ::: .. ::: :: : : .
NP_003 VLTLLGLLHGLVLLPVLLSILGPPPEVI------QMYKESPEILSPP-----APQGGGLR
1100 1110 1120 1130 1140
1220 1230 1240 1250 1260 1270
pF1KE0 SGSDSSDSEYSSQTTVSGLSEELRHYEAQQGAGGPAHQVIVEATENPVFAHSTVVHPESR
:..:: . ...:.:
NP_003 WGASSSLPQSFARVTTSMTVAIHPPPLPGAYIHPAPDEPPWSPAATSSGNLSSRGPGPAT
1150 1160 1170 1180 1190 1200
>>XP_011524317 (OMIM: 257220,607623) PREDICTED: Niemann- (1148 aa)
initn: 580 init1: 365 opt: 439 Z-score: 283.2 bits: 64.7 E(85289): 4.9e-09
Smith-Waterman score: 697; 25.8% identity (53.5% similar) in 821 aa overlap (387-1177:433-1112)
360 370 380 390 400 410
pF1KE0 AHALQTMFQLMTPKQMYEHFKGYEYVSHINWNEDKAAAILEAWQRTYVEVVHQSVAQNST
.:. . .::.. ... :.. : :
XP_011 VFPWLVLGGYDDQNYNNATALVITFPVNNYYNDTEKLQRAQAWEKEFINFVKNYKNPNLT
410 420 430 440 450 460
420 430 440 450 460 470
pF1KE0 QKVLSFTTT-TLDDILKSFSDVSVIRVASGYLLMLAYACLTMLRW-DCSK----SQGAVG
.:::. ...: :. :: .:. :. .: .:. : :.. . .: . :. ..:
XP_011 ---ISFTAERSIEDELNRESDSDVFTVVISYAIMFLYISLALGHMKSCRRLLVDSKVSLG
470 480 490 500 510
480 490 500 510 520 530
pF1KE0 LAGVLLVALSVAAGLGLCSLIGISFNAATTQVLPFLALGVGVDDVFLLAHAFSETGQNKR
.::.:.: ::: .::. : ::. .. . .:.:::.:.::::..:.:..:... . .
XP_011 IAGILIVLSSVACSLGVFSYIGLPLTLIVIEVIPFLVLAVGVDNIFILVQAYQRDERLQG
520 530 540 550 560 570
540 550 560 570 580 590
pF1KE0 IPFEDRTGECLKRTGASVALTSISNVTAFFMAALIPIPALRAFSLQAAVVVVFNFAMVLL
.... :. : ... :. :.:.:...:::..:: .::...::: :...: ..: . .
XP_011 ETLDQQLGRVLGEVAPSMFLSSFSETVAFFLGALSVMPAVHTFSLFAGLAVFIDFLLQIT
580 590 600 610 620 630
600 610 620 630 640 650
pF1KE0 IFPAILSMDLYRREDRRLDIFCCFTSPCVSRVIQVEPQAYTDTHDNTRYSPPPPYSSHSF
: ..:..:. :.: :::::::
XP_011 CFVSLLGLDIKRQEKNRLDIFCC-------------------------------------
640 650 660
660 670 680 690 700 710
pF1KE0 AHETQITMQSTVQLRTEYDPHTHVYYTTAEPRSEISVQPVTVTQDTLSCQSPESTSSTRD
: ..: : :. ::
XP_011 ---------------------------------------VRGAEDGTSVQASES------
670
720 730 740 750 760 770
pF1KE0 LLSQFSDSSLHCLEPPCTKWTLSSFAEKHYAPFLLKPKAKVVVIFLFLGLLGVSLYGTTR
: : : .. :.:.::: . .:: .:.:.:. :. ..
XP_011 ----------------C----LFRFFKNSYSPLLLKDWMRPIVIAIFVGVLSFSIAVLNK
680 690 700 710
780 790 800 810 820
pF1KE0 VRDGLDLTDIVPRETREYDFIAAQFKYF-SFYNMYIVTQKA-DYPNI--QHLLYDLHRSF
: ::: . .: .. :.. . .:. . .:.: ... :: . :...
XP_011 VDIGLDQSLSMPDDSYMVDYFKSISQYLHAGPPVYFVLEEGHDYTSSKGQNMVCGGMGCN
720 730 740 750 760 770
830 840 850 860 870
pF1KE0 SNVKYVMLEENKQL---------PKMWLHYFRDWLQGLQDAFDSDWETGKIMPNNYKNGS
.. .. . :: :. :. . ::.. .. : . ... :.:
XP_011 NDSLVQQIFNAAQLDNYTRIGFAPSSWIDDYFDWVKPQSSCCRVD-----NITDQFCNAS
780 790 800 810 820 830
880 890 900 910 920 930
pF1KE0 DDGVLAYKLLVQTGSRDKPIDISQLTKQRLVDADGIINPSAFYIYLTAWVSNDPVAYAAS
.. . : .:. . ::: .: :. .: ..:..:
XP_011 --------VVDPACVRCRPL--TPEGKQRPQGGD-------FMRFLPMFLSDNP------
840 850 860
940 950 960 970 980 990
pF1KE0 QANIRPHRPEWVHDKADYMPETRLRIPAAEPIEYAQFPFYLNGLRDTSDFVEAIEKVRTI
:. . : : : . . . . . . : : . :. ..::..:..:.: :
XP_011 ----NPKCGKGGH--AAYSSAVNILLGHGTRVGATYFMTYHTVLQTSADFIDALKKARLI
870 880 890 900 910 920
1000 1010 1020 1030 1040 1050
pF1KE0 CSNYT-SLGLSS-----YPNGYPFLFWEQYIGLRHWLLLFISVVLACTFLVCAVFL-LNP
:: : ..:... .: . ..:.:::. . .. ..: :. ::: :.: .
XP_011 ASNVTETMGINGSAYRVFPYSVFYVFYEQYLTIIDDTIFNLGVSLGAIFLVTMVLLGCEL
930 940 950 960 970 980
1060 1070 1080 1090 1100
pF1KE0 WTAGIIVMVLALMTVELFGMMGLIGIKLSAVPVVILIASVGIGVEFTVHVALAFLTAI-G
:.: :. ..:.. :..::.: : ::.:.:: .: :. : ::.::: :.. :: ... :
XP_011 WSAVIMCATIAMVLVNMFGVMWLWGISLNAVSLVNLVMSCGISVEFCSHITRAFTVSMKG
990 1000 1010 1020 1030 1040
1110 1120 1130 1140 1150 1160
pF1KE0 DKNRRAVLALEHMFAPVLDGAVSTLLG---VLMLAGSEFDFIVRYFFAVLAILTILGVLN
.. .:: :: :: . :..: . : .: :: .: :.. : . :: :: ...::. .
XP_011 SRVERAEEALAHMGSSVFSGITLTKFGGIVVLAFAKSQI-FQIFYFRMYLA-MVLLGATH
1050 1060 1070 1080 1090 1100
1170 1180 1190 1200 1210 1220
pF1KE0 GLVLLPVLLSFFGPYPEVSPANGLNRLPTPSPEPPPSVVRFAMPPGHTHSGSDSSDSEYS
::..::::::.
XP_011 GLIFLPVLLSYIAKLLERTIYLCISQHIHYATQMAPLQCLMTASDRC
1110 1120 1130 1140
1447 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 04:12:25 2016 done: Fri Nov 4 04:12:28 2016
Total Scan time: 19.710 Total Display time: 0.810
Function used was FASTA [36.3.4 Apr, 2011]