Result of FASTA (omim) for
pFN21AB6944
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB6944, 231 aa
1>>>pF1KB6944 231 - 231 aa - 231 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.0586+/-0.000324; mu= 15.3870+/- 0.020
mean_var=60.1234+/-11.783, 0's: 0 Z-trim(116.3): 33 B-trim: 69 in 1/56
Lambda= 0.165406
statistics sampled from 27305 (27338) to 27305 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.715), E-opt: 0.2 (0.321), width: 16
Scan time: 5.970
The best scores are: opt bits E(85289)
NP_002564 (OMIM: 603074) platelet-activating facto ( 231) 1601 390.0 1.8e-108
NP_001139411 (OMIM: 603074) platelet-activating fa ( 231) 1601 390.0 1.8e-108
NP_001139412 (OMIM: 603074) platelet-activating fa ( 231) 1601 390.0 1.8e-108
NP_002563 (OMIM: 602508) platelet-activating facto ( 229) 1040 256.1 3.6e-68
XP_016873329 (OMIM: 602508) PREDICTED: platelet-ac ( 242) 1040 256.1 3.8e-68
XP_016882336 (OMIM: 603074) PREDICTED: platelet-ac ( 218) 857 212.4 4.8e-55
XP_016882335 (OMIM: 603074) PREDICTED: platelet-ac ( 218) 857 212.4 4.8e-55
XP_016882337 (OMIM: 603074) PREDICTED: platelet-ac ( 218) 857 212.4 4.8e-55
NP_001296360 (OMIM: 602508) platelet-activating fa ( 181) 823 204.3 1.1e-52
NP_001171675 (OMIM: 602508) platelet-activating fa ( 202) 722 180.2 2.3e-45
NP_001171676 (OMIM: 602508) platelet-activating fa ( 155) 714 178.2 6.8e-45
NP_001171677 (OMIM: 602508) platelet-activating fa ( 132) 693 173.2 1.9e-43
>>NP_002564 (OMIM: 603074) platelet-activating factor ac (231 aa)
initn: 1601 init1: 1601 opt: 1601 Z-score: 2068.3 bits: 390.0 E(85289): 1.8e-108
Smith-Waterman score: 1601; 100.0% identity (100.0% similar) in 231 aa overlap (1-231:1-231)
10 20 30 40 50 60
pF1KB6 MSGEENPASKPTPVQDVQGDGRWMSLHHRFVADSKDKEPEVVFIGDSLVQLMHQCEIWRE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 MSGEENPASKPTPVQDVQGDGRWMSLHHRFVADSKDKEPEVVFIGDSLVQLMHQCEIWRE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB6 LFSPLHALNFGIGGDGTQHVLWRLENGELEHIRPKIVVVWVGTNNHGHTAEQVTGGIKAI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 LFSPLHALNFGIGGDGTQHVLWRLENGELEHIRPKIVVVWVGTNNHGHTAEQVTGGIKAI
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB6 VQLVNERQPQARVVVLGLLPRGQHPNPLREKNRQVNELVRAALAGHPRAHFLDADPGFVH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 VQLVNERQPQARVVVLGLLPRGQHPNPLREKNRQVNELVRAALAGHPRAHFLDADPGFVH
130 140 150 160 170 180
190 200 210 220 230
pF1KB6 SDGTISHHDMYDYLHLSRLGYTPVCRALHSLLLRLLAQDQGQGAPLLEPAP
:::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 SDGTISHHDMYDYLHLSRLGYTPVCRALHSLLLRLLAQDQGQGAPLLEPAP
190 200 210 220 230
>>NP_001139411 (OMIM: 603074) platelet-activating factor (231 aa)
initn: 1601 init1: 1601 opt: 1601 Z-score: 2068.3 bits: 390.0 E(85289): 1.8e-108
Smith-Waterman score: 1601; 100.0% identity (100.0% similar) in 231 aa overlap (1-231:1-231)
10 20 30 40 50 60
pF1KB6 MSGEENPASKPTPVQDVQGDGRWMSLHHRFVADSKDKEPEVVFIGDSLVQLMHQCEIWRE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MSGEENPASKPTPVQDVQGDGRWMSLHHRFVADSKDKEPEVVFIGDSLVQLMHQCEIWRE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB6 LFSPLHALNFGIGGDGTQHVLWRLENGELEHIRPKIVVVWVGTNNHGHTAEQVTGGIKAI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LFSPLHALNFGIGGDGTQHVLWRLENGELEHIRPKIVVVWVGTNNHGHTAEQVTGGIKAI
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB6 VQLVNERQPQARVVVLGLLPRGQHPNPLREKNRQVNELVRAALAGHPRAHFLDADPGFVH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VQLVNERQPQARVVVLGLLPRGQHPNPLREKNRQVNELVRAALAGHPRAHFLDADPGFVH
130 140 150 160 170 180
190 200 210 220 230
pF1KB6 SDGTISHHDMYDYLHLSRLGYTPVCRALHSLLLRLLAQDQGQGAPLLEPAP
:::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SDGTISHHDMYDYLHLSRLGYTPVCRALHSLLLRLLAQDQGQGAPLLEPAP
190 200 210 220 230
>>NP_001139412 (OMIM: 603074) platelet-activating factor (231 aa)
initn: 1601 init1: 1601 opt: 1601 Z-score: 2068.3 bits: 390.0 E(85289): 1.8e-108
Smith-Waterman score: 1601; 100.0% identity (100.0% similar) in 231 aa overlap (1-231:1-231)
10 20 30 40 50 60
pF1KB6 MSGEENPASKPTPVQDVQGDGRWMSLHHRFVADSKDKEPEVVFIGDSLVQLMHQCEIWRE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MSGEENPASKPTPVQDVQGDGRWMSLHHRFVADSKDKEPEVVFIGDSLVQLMHQCEIWRE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB6 LFSPLHALNFGIGGDGTQHVLWRLENGELEHIRPKIVVVWVGTNNHGHTAEQVTGGIKAI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LFSPLHALNFGIGGDGTQHVLWRLENGELEHIRPKIVVVWVGTNNHGHTAEQVTGGIKAI
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB6 VQLVNERQPQARVVVLGLLPRGQHPNPLREKNRQVNELVRAALAGHPRAHFLDADPGFVH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VQLVNERQPQARVVVLGLLPRGQHPNPLREKNRQVNELVRAALAGHPRAHFLDADPGFVH
130 140 150 160 170 180
190 200 210 220 230
pF1KB6 SDGTISHHDMYDYLHLSRLGYTPVCRALHSLLLRLLAQDQGQGAPLLEPAP
:::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SDGTISHHDMYDYLHLSRLGYTPVCRALHSLLLRLLAQDQGQGAPLLEPAP
190 200 210 220 230
>>NP_002563 (OMIM: 602508) platelet-activating factor ac (229 aa)
initn: 1047 init1: 1031 opt: 1040 Z-score: 1344.8 bits: 256.1 E(85289): 3.6e-68
Smith-Waterman score: 1040; 65.3% identity (88.0% similar) in 216 aa overlap (3-218:4-219)
10 20 30 40 50
pF1KB6 MSGEENPASKPTPVQDVQGDGRWMSLHHRFVADSKDKEPEVVFIGDSLVQLMHQCEIWR
:. :::. : ..:.::: :::: :.::: : :::::.:.:.:::.::::.: ::::
NP_002 MSQGDSNPAAIPHAAEDIQGDDRWMSQHNRFVLDCKDKEPDVLFVGDSMVQLMQQYEIWR
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB6 ELFSPLHALNFGIGGDGTQHVLWRLENGELEHIRPKIVVVWVGTNNHGHTAEQVTGGIKA
:::::::::::::::: :.::::::.:::::.:.::..::::::::: .:::.:.:::.:
NP_002 ELFSPLHALNFGIGGDTTRHVLWRLKNGELENIKPKVIVVWVGTNNHENTAEEVAGGIEA
70 80 90 100 110 120
120 130 140 150 160 170
pF1KB6 IVQLVNERQPQARVVVLGLLPRGQHPNPLREKNRQVNELVRAALAGHPRAHFLDADPGFV
::::.: :::::...::::::::..:::::.:: .::.:....: ...::.: :::
NP_002 IVQLINTRQPQAKIIVLGLLPRGEKPNPLRQKNAKVNQLLKVSLPKLANVQLLDTDGGFV
130 140 150 160 170 180
180 190 200 210 220 230
pF1KB6 HSDGTISHHDMYDYLHLSRLGYTPVCRALHSLLLRLLAQDQGQGAPLLEPAP
::::.:: :::.:.:::. ::. .:. :: :...:: .
NP_002 HSDGAISCHDMFDFLHLTGGGYAKICKPLHELIMQLLEETPEEKQTTIA
190 200 210 220
>>XP_016873329 (OMIM: 602508) PREDICTED: platelet-activa (242 aa)
initn: 1049 init1: 1031 opt: 1040 Z-score: 1344.5 bits: 256.1 E(85289): 3.8e-68
Smith-Waterman score: 1040; 65.3% identity (88.0% similar) in 216 aa overlap (3-218:17-232)
10 20 30 40
pF1KB6 MSGEENPASKPTPVQDVQGDGRWMSLHHRFVADSKDKEPEVVFIGD
:. :::. : ..:.::: :::: :.::: : :::::.:.:.::
XP_016 MCSERLVTCPRCRMSQGDSNPAAIPHAAEDIQGDDRWMSQHNRFVLDCKDKEPDVLFVGD
10 20 30 40 50 60
50 60 70 80 90 100
pF1KB6 SLVQLMHQCEIWRELFSPLHALNFGIGGDGTQHVLWRLENGELEHIRPKIVVVWVGTNNH
:.::::.: :::::::::::::::::::: :.::::::.:::::.:.::..:::::::::
XP_016 SMVQLMQQYEIWRELFSPLHALNFGIGGDTTRHVLWRLKNGELENIKPKVIVVWVGTNNH
70 80 90 100 110 120
110 120 130 140 150 160
pF1KB6 GHTAEQVTGGIKAIVQLVNERQPQARVVVLGLLPRGQHPNPLREKNRQVNELVRAALAGH
.:::.:.:::.:::::.: :::::...::::::::..:::::.:: .::.:....:
XP_016 ENTAEEVAGGIEAIVQLINTRQPQAKIIVLGLLPRGEKPNPLRQKNAKVNQLLKVSLPKL
130 140 150 160 170 180
170 180 190 200 210 220
pF1KB6 PRAHFLDADPGFVHSDGTISHHDMYDYLHLSRLGYTPVCRALHSLLLRLLAQDQGQGAPL
...::.: :::::::.:: :::.:.:::. ::. .:. :: :...:: .
XP_016 ANVQLLDTDGGFVHSDGAISCHDMFDFLHLTGGGYAKICKPLHELIMQLLEETPEEKQTT
190 200 210 220 230 240
230
pF1KB6 LEPAP
XP_016 IA
>>XP_016882336 (OMIM: 603074) PREDICTED: platelet-activa (218 aa)
initn: 857 init1: 857 opt: 857 Z-score: 1109.1 bits: 212.4 E(85289): 4.8e-55
Smith-Waterman score: 1484; 94.4% identity (94.4% similar) in 231 aa overlap (1-231:1-218)
10 20 30 40 50 60
pF1KB6 MSGEENPASKPTPVQDVQGDGRWMSLHHRFVADSKDKEPEVVFIGDSLVQLMHQCEIWRE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MSGEENPASKPTPVQDVQGDGRWMSLHHRFVADSKDKEPEVVFIGDSLVQLMHQCEIWRE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB6 LFSPLHALNFGIGGDGTQHVLWRLENGELEHIRPKIVVVWVGTNNHGHTAEQVTGGIKAI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LFSPLHALNFGIGGDGTQHVLWRLENGELEHIRPKIVVVWVGTNNHGHTAEQVTGGIKAI
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB6 VQLVNERQPQARVVVLGLLPRGQHPNPLREKNRQVNELVRAALAGHPRAHFLDADPGFVH
::: ::::::::::::::::::::::::::::::::::::::::::::
XP_016 VQL-------------GLLPRGQHPNPLREKNRQVNELVRAALAGHPRAHFLDADPGFVH
130 140 150 160
190 200 210 220 230
pF1KB6 SDGTISHHDMYDYLHLSRLGYTPVCRALHSLLLRLLAQDQGQGAPLLEPAP
:::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SDGTISHHDMYDYLHLSRLGYTPVCRALHSLLLRLLAQDQGQGAPLLEPAP
170 180 190 200 210
>>XP_016882335 (OMIM: 603074) PREDICTED: platelet-activa (218 aa)
initn: 857 init1: 857 opt: 857 Z-score: 1109.1 bits: 212.4 E(85289): 4.8e-55
Smith-Waterman score: 1484; 94.4% identity (94.4% similar) in 231 aa overlap (1-231:1-218)
10 20 30 40 50 60
pF1KB6 MSGEENPASKPTPVQDVQGDGRWMSLHHRFVADSKDKEPEVVFIGDSLVQLMHQCEIWRE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MSGEENPASKPTPVQDVQGDGRWMSLHHRFVADSKDKEPEVVFIGDSLVQLMHQCEIWRE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB6 LFSPLHALNFGIGGDGTQHVLWRLENGELEHIRPKIVVVWVGTNNHGHTAEQVTGGIKAI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LFSPLHALNFGIGGDGTQHVLWRLENGELEHIRPKIVVVWVGTNNHGHTAEQVTGGIKAI
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB6 VQLVNERQPQARVVVLGLLPRGQHPNPLREKNRQVNELVRAALAGHPRAHFLDADPGFVH
::: ::::::::::::::::::::::::::::::::::::::::::::
XP_016 VQL-------------GLLPRGQHPNPLREKNRQVNELVRAALAGHPRAHFLDADPGFVH
130 140 150 160
190 200 210 220 230
pF1KB6 SDGTISHHDMYDYLHLSRLGYTPVCRALHSLLLRLLAQDQGQGAPLLEPAP
:::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SDGTISHHDMYDYLHLSRLGYTPVCRALHSLLLRLLAQDQGQGAPLLEPAP
170 180 190 200 210
>>XP_016882337 (OMIM: 603074) PREDICTED: platelet-activa (218 aa)
initn: 857 init1: 857 opt: 857 Z-score: 1109.1 bits: 212.4 E(85289): 4.8e-55
Smith-Waterman score: 1484; 94.4% identity (94.4% similar) in 231 aa overlap (1-231:1-218)
10 20 30 40 50 60
pF1KB6 MSGEENPASKPTPVQDVQGDGRWMSLHHRFVADSKDKEPEVVFIGDSLVQLMHQCEIWRE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MSGEENPASKPTPVQDVQGDGRWMSLHHRFVADSKDKEPEVVFIGDSLVQLMHQCEIWRE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB6 LFSPLHALNFGIGGDGTQHVLWRLENGELEHIRPKIVVVWVGTNNHGHTAEQVTGGIKAI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LFSPLHALNFGIGGDGTQHVLWRLENGELEHIRPKIVVVWVGTNNHGHTAEQVTGGIKAI
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB6 VQLVNERQPQARVVVLGLLPRGQHPNPLREKNRQVNELVRAALAGHPRAHFLDADPGFVH
::: ::::::::::::::::::::::::::::::::::::::::::::
XP_016 VQL-------------GLLPRGQHPNPLREKNRQVNELVRAALAGHPRAHFLDADPGFVH
130 140 150 160
190 200 210 220 230
pF1KB6 SDGTISHHDMYDYLHLSRLGYTPVCRALHSLLLRLLAQDQGQGAPLLEPAP
:::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SDGTISHHDMYDYLHLSRLGYTPVCRALHSLLLRLLAQDQGQGAPLLEPAP
170 180 190 200 210
>>NP_001296360 (OMIM: 602508) platelet-activating factor (181 aa)
initn: 836 init1: 820 opt: 823 Z-score: 1066.5 bits: 204.3 E(85289): 1.1e-52
Smith-Waterman score: 823; 66.1% identity (89.5% similar) in 171 aa overlap (48-218:1-171)
20 30 40 50 60 70
pF1KB6 QGDGRWMSLHHRFVADSKDKEPEVVFIGDSLVQLMHQCEIWRELFSPLHALNFGIGGDGT
.::::.: :::::::::::::::::::: :
NP_001 MVQLMQQYEIWRELFSPLHALNFGIGGDTT
10 20 30
80 90 100 110 120 130
pF1KB6 QHVLWRLENGELEHIRPKIVVVWVGTNNHGHTAEQVTGGIKAIVQLVNERQPQARVVVLG
.::::::.:::::.:.::..::::::::: .:::.:.:::.:::::.: :::::...:::
NP_001 RHVLWRLKNGELENIKPKVIVVWVGTNNHENTAEEVAGGIEAIVQLINTRQPQAKIIVLG
40 50 60 70 80 90
140 150 160 170 180 190
pF1KB6 LLPRGQHPNPLREKNRQVNELVRAALAGHPRAHFLDADPGFVHSDGTISHHDMYDYLHLS
:::::..:::::.:: .::.:....: ...::.: :::::::.:: :::.:.:::.
NP_001 LLPRGEKPNPLRQKNAKVNQLLKVSLPKLANVQLLDTDGGFVHSDGAISCHDMFDFLHLT
100 110 120 130 140 150
200 210 220 230
pF1KB6 RLGYTPVCRALHSLLLRLLAQDQGQGAPLLEPAP
::. .:. :: :...:: .
NP_001 GGGYAKICKPLHELIMQLLEETPEEKQTTIA
160 170 180
>>NP_001171675 (OMIM: 602508) platelet-activating factor (202 aa)
initn: 722 init1: 722 opt: 722 Z-score: 935.5 bits: 180.2 E(85289): 2.3e-45
Smith-Waterman score: 722; 72.6% identity (91.1% similar) in 135 aa overlap (3-137:4-138)
10 20 30 40 50
pF1KB6 MSGEENPASKPTPVQDVQGDGRWMSLHHRFVADSKDKEPEVVFIGDSLVQLMHQCEIWR
:. :::. : ..:.::: :::: :.::: : :::::.:.:.:::.::::.: ::::
NP_001 MSQGDSNPAAIPHAAEDIQGDDRWMSQHNRFVLDCKDKEPDVLFVGDSMVQLMQQYEIWR
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB6 ELFSPLHALNFGIGGDGTQHVLWRLENGELEHIRPKIVVVWVGTNNHGHTAEQVTGGIKA
:::::::::::::::: :.::::::.:::::.:.::..::::::::: .:::.:.:::.:
NP_001 ELFSPLHALNFGIGGDTTRHVLWRLKNGELENIKPKVIVVWVGTNNHENTAEEVAGGIEA
70 80 90 100 110 120
120 130 140 150 160 170
pF1KB6 IVQLVNERQPQARVVVLGLLPRGQHPNPLREKNRQVNELVRAALAGHPRAHFLDADPGFV
::::.: :::::...:::
NP_001 IVQLINTRQPQAKIIVLGKAAASKYSISEIVRLEQGSVNWSIGTYPDDTPATTRPAILQL
130 140 150 160 170 180
231 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 11:33:43 2016 done: Fri Nov 4 11:33:44 2016
Total Scan time: 5.970 Total Display time: 0.000
Function used was FASTA [36.3.4 Apr, 2011]