Result of FASTA (ccds) for
pFN21AB6438
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB6438, 340 aa
1>>>pF1KB6438 340 - 340 aa - 340 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.8363+/-0.000707; mu= 14.8396+/- 0.043
mean_var=87.8107+/-17.263, 0's: 0 Z-trim(111.9): 85 B-trim: 74 in 1/51
Lambda= 0.136868
statistics sampled from 12655 (12742) to 12655 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.753), E-opt: 0.2 (0.391), width: 16
Scan time: 2.450
The best scores are: opt bits E(32554)
CCDS43096.1 RASSF1 gene_id:11186|Hs108|chr3 ( 340) 2348 473.0 1.6e-133
CCDS2820.1 RASSF1 gene_id:11186|Hs108|chr3 ( 344) 2320 467.5 7.2e-132
CCDS2821.1 RASSF1 gene_id:11186|Hs108|chr3 ( 270) 1463 298.2 5.2e-81
CCDS2822.1 RASSF1 gene_id:11186|Hs108|chr3 ( 189) 1251 256.2 1.6e-68
CCDS30998.1 RASSF5 gene_id:83593|Hs108|chr1 ( 418) 942 195.4 6.9e-50
CCDS1464.1 RASSF5 gene_id:83593|Hs108|chr1 ( 265) 754 158.2 7.1e-39
CCDS1463.1 RASSF5 gene_id:83593|Hs108|chr1 ( 336) 628 133.4 2.7e-31
CCDS8969.1 RASSF3 gene_id:283349|Hs108|chr12 ( 238) 430 94.2 1.2e-19
>>CCDS43096.1 RASSF1 gene_id:11186|Hs108|chr3 (340 aa)
initn: 2348 init1: 2348 opt: 2348 Z-score: 2510.8 bits: 473.0 E(32554): 1.6e-133
Smith-Waterman score: 2348; 100.0% identity (100.0% similar) in 340 aa overlap (1-340:1-340)
10 20 30 40 50 60
pF1KB6 MSGEPELIELRELAPAGRAGKGRTRLERANALRIARGTACNPTRQLVPGRGHRFQPAGPA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS43 MSGEPELIELRELAPAGRAGKGRTRLERANALRIARGTACNPTRQLVPGRGHRFQPAGPA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB6 THTWCDLCGDFIWGVVRKGLQCAHCKFTCHYRCRALVCLDCCGPRDLGWEPAVERDTNVD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS43 THTWCDLCGDFIWGVVRKGLQCAHCKFTCHYRCRALVCLDCCGPRDLGWEPAVERDTNVD
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB6 EPVEWETPDLSQAEIEQKIKEYNAQINSNLFMSLNKDGSYTGFIKVQLKLVRPVSVPSSK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS43 EPVEWETPDLSQAEIEQKIKEYNAQINSNLFMSLNKDGSYTGFIKVQLKLVRPVSVPSSK
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB6 KPPSLQDARRGPGRGTSVRRRTSFYLPKDAVKHLHVLSRTRAREVIEALLRKFLVVDDPR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS43 KPPSLQDARRGPGRGTSVRRRTSFYLPKDAVKHLHVLSRTRAREVIEALLRKFLVVDDPR
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB6 KFALFERAERHGQVYLRKLLDDEQPLRLRLLAGPSDKALSFVLKENDSGEVNWDAFSMPE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS43 KFALFERAERHGQVYLRKLLDDEQPLRLRLLAGPSDKALSFVLKENDSGEVNWDAFSMPE
250 260 270 280 290 300
310 320 330 340
pF1KB6 LHNFLRILQREEEEHLRQILQKYSYCRQKIQEALHACPLG
::::::::::::::::::::::::::::::::::::::::
CCDS43 LHNFLRILQREEEEHLRQILQKYSYCRQKIQEALHACPLG
310 320 330 340
>>CCDS2820.1 RASSF1 gene_id:11186|Hs108|chr3 (344 aa)
initn: 1749 init1: 1749 opt: 2320 Z-score: 2480.9 bits: 467.5 E(32554): 7.2e-132
Smith-Waterman score: 2320; 98.5% identity (98.8% similar) in 344 aa overlap (1-340:1-344)
10 20 30 40 50 60
pF1KB6 MSGEPELIELRELAPAGRAGKGRTRLERANALRIARGTACNPTRQLVPGRGHRFQPAGPA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS28 MSGEPELIELRELAPAGRAGKGRTRLERANALRIARGTACNPTRQLVPGRGHRFQPAGPA
10 20 30 40 50 60
70 80 90 100 110
pF1KB6 THTWCDLCGDFIWGVVRKGLQCAH----CKFTCHYRCRALVCLDCCGPRDLGWEPAVERD
:::::::::::::::::::::::. ::::::::::::::::::::::::::::::::
CCDS28 THTWCDLCGDFIWGVVRKGLQCARLSADCKFTCHYRCRALVCLDCCGPRDLGWEPAVERD
70 80 90 100 110 120
120 130 140 150 160 170
pF1KB6 TNVDEPVEWETPDLSQAEIEQKIKEYNAQINSNLFMSLNKDGSYTGFIKVQLKLVRPVSV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS28 TNVDEPVEWETPDLSQAEIEQKIKEYNAQINSNLFMSLNKDGSYTGFIKVQLKLVRPVSV
130 140 150 160 170 180
180 190 200 210 220 230
pF1KB6 PSSKKPPSLQDARRGPGRGTSVRRRTSFYLPKDAVKHLHVLSRTRAREVIEALLRKFLVV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS28 PSSKKPPSLQDARRGPGRGTSVRRRTSFYLPKDAVKHLHVLSRTRAREVIEALLRKFLVV
190 200 210 220 230 240
240 250 260 270 280 290
pF1KB6 DDPRKFALFERAERHGQVYLRKLLDDEQPLRLRLLAGPSDKALSFVLKENDSGEVNWDAF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS28 DDPRKFALFERAERHGQVYLRKLLDDEQPLRLRLLAGPSDKALSFVLKENDSGEVNWDAF
250 260 270 280 290 300
300 310 320 330 340
pF1KB6 SMPELHNFLRILQREEEEHLRQILQKYSYCRQKIQEALHACPLG
::::::::::::::::::::::::::::::::::::::::::::
CCDS28 SMPELHNFLRILQREEEEHLRQILQKYSYCRQKIQEALHACPLG
310 320 330 340
>>CCDS2821.1 RASSF1 gene_id:11186|Hs108|chr3 (270 aa)
initn: 1463 init1: 1463 opt: 1463 Z-score: 1567.9 bits: 298.2 E(32554): 5.2e-81
Smith-Waterman score: 1463; 100.0% identity (100.0% similar) in 221 aa overlap (120-340:50-270)
90 100 110 120 130 140
pF1KB6 HYRCRALVCLDCCGPRDLGWEPAVERDTNVDEPVEWETPDLSQAEIEQKIKEYNAQINSN
::::::::::::::::::::::::::::::
CCDS28 GYCSQEDSDSELEQYFTARTSLARRPRRDQDEPVEWETPDLSQAEIEQKIKEYNAQINSN
20 30 40 50 60 70
150 160 170 180 190 200
pF1KB6 LFMSLNKDGSYTGFIKVQLKLVRPVSVPSSKKPPSLQDARRGPGRGTSVRRRTSFYLPKD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS28 LFMSLNKDGSYTGFIKVQLKLVRPVSVPSSKKPPSLQDARRGPGRGTSVRRRTSFYLPKD
80 90 100 110 120 130
210 220 230 240 250 260
pF1KB6 AVKHLHVLSRTRAREVIEALLRKFLVVDDPRKFALFERAERHGQVYLRKLLDDEQPLRLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS28 AVKHLHVLSRTRAREVIEALLRKFLVVDDPRKFALFERAERHGQVYLRKLLDDEQPLRLR
140 150 160 170 180 190
270 280 290 300 310 320
pF1KB6 LLAGPSDKALSFVLKENDSGEVNWDAFSMPELHNFLRILQREEEEHLRQILQKYSYCRQK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS28 LLAGPSDKALSFVLKENDSGEVNWDAFSMPELHNFLRILQREEEEHLRQILQKYSYCRQK
200 210 220 230 240 250
330 340
pF1KB6 IQEALHACPLG
:::::::::::
CCDS28 IQEALHACPLG
260 270
>>CCDS2822.1 RASSF1 gene_id:11186|Hs108|chr3 (189 aa)
initn: 1251 init1: 1251 opt: 1251 Z-score: 1343.8 bits: 256.2 E(32554): 1.6e-68
Smith-Waterman score: 1251; 100.0% identity (100.0% similar) in 189 aa overlap (152-340:1-189)
130 140 150 160 170 180
pF1KB6 PVEWETPDLSQAEIEQKIKEYNAQINSNLFMSLNKDGSYTGFIKVQLKLVRPVSVPSSKK
::::::::::::::::::::::::::::::
CCDS28 MSLNKDGSYTGFIKVQLKLVRPVSVPSSKK
10 20 30
190 200 210 220 230 240
pF1KB6 PPSLQDARRGPGRGTSVRRRTSFYLPKDAVKHLHVLSRTRAREVIEALLRKFLVVDDPRK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS28 PPSLQDARRGPGRGTSVRRRTSFYLPKDAVKHLHVLSRTRAREVIEALLRKFLVVDDPRK
40 50 60 70 80 90
250 260 270 280 290 300
pF1KB6 FALFERAERHGQVYLRKLLDDEQPLRLRLLAGPSDKALSFVLKENDSGEVNWDAFSMPEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS28 FALFERAERHGQVYLRKLLDDEQPLRLRLLAGPSDKALSFVLKENDSGEVNWDAFSMPEL
100 110 120 130 140 150
310 320 330 340
pF1KB6 HNFLRILQREEEEHLRQILQKYSYCRQKIQEALHACPLG
:::::::::::::::::::::::::::::::::::::::
CCDS28 HNFLRILQREEEEHLRQILQKYSYCRQKIQEALHACPLG
160 170 180
>>CCDS30998.1 RASSF5 gene_id:83593|Hs108|chr1 (418 aa)
initn: 928 init1: 754 opt: 942 Z-score: 1009.1 bits: 195.4 E(32554): 6.9e-50
Smith-Waterman score: 942; 47.3% identity (71.6% similar) in 338 aa overlap (11-334:81-410)
10 20 30 40
pF1KB6 MSGEPELIELRELAPAGRAGKGRTRLERANALRIARGTAC
: : : : . : : : : .:.
CCDS30 STAPGAREGRSARRAARGNLEPPPRASRPARPLRP-GLQQRLRRR-PGAPRPRDVRSIFE
60 70 80 90 100
50 60 70 80 90
pF1KB6 NPTRQLVP---GRGHRFQ----PAGPATHTWCDLCGDFIWGVVRKGLQCAHCKFTCHYRC
.: :: :.:: : :.::. :::::: :.:..:.:..:::::: .:
CCDS30 QPQDPRVPAERGEGHCFAELVLPGGPG---WCDLCGRE---VLRQALRCTNCKFTCHPEC
110 120 130 140 150 160
100 110 120 130 140
pF1KB6 RALVCLDCCGPRDLGWE-PAVER------DTNVDEPVEWETPDLSQAEIEQKIKEYNAQI
:.:. ::: . :. . :. : . :: .::: . ::.::: ::..
CCDS30 RSLIQLDCSQQEGLSRDRPSPESTLTVTFSQNVCKPVEETQRPPTLQEIKQKIDSYNTRE
170 180 190 200 210 220
150 160 170 180 190 200
pF1KB6 NSNLFMSLNKDGSYTGFIKVQLKLVRPVSVPSSKKPPSLQDARRGPGRGTSVRRRTSFYL
.. : :.:..::.:::::::.::: :::.::.. .: :. :: . . .... .::::::
CCDS30 KNCLGMKLSEDGTYTGFIKVHLKLRRPVTVPAGIRPQSIYDAIKEVNLAATTDKRTSFYL
230 240 250 260 270 280
210 220 230 240 250 260
pF1KB6 PKDAVKHLHVLSRTRAREVIEALLRKFLVVDDPRKFALFERAERHGQVYLRKLLDDEQPL
: ::.:.::. : : . :::..::.::.:::.:.:::::.: .. ::: ..:: ..::
CCDS30 PLDAIKQLHISSTTTVSEVIQGLLKKFMVVDNPQKFALFKRIHKDGQVLFQKLSIADRPL
290 300 310 320 330 340
270 280 290 300 310 320
pF1KB6 RLRLLAGPSDKALSFVLKENDSGEVNWDAFSMPELHNFLRILQREEEEHLRQILQKYSYC
:::::::. ..::::::::..:::.:::::.:::.::: ::..::.....:. .::.
CCDS30 YLRLLAGPDTEVLSFVLKENETGEVEWDAFSIPELQNFLTILEKEEQDKIQQVQKKYDKF
350 360 370 380 390 400
330 340
pF1KB6 RQKIQEALHACPLG
:::..:::
CCDS30 RQKLEEALRESQGKPG
410
>>CCDS1464.1 RASSF5 gene_id:83593|Hs108|chr1 (265 aa)
initn: 754 init1: 754 opt: 754 Z-score: 811.4 bits: 158.2 E(32554): 7.1e-39
Smith-Waterman score: 754; 53.5% identity (81.6% similar) in 217 aa overlap (118-334:41-257)
90 100 110 120 130 140
pF1KB6 TCHYRCRALVCLDCCGPRDLGWEPAVERDTNVDEPVEWETPDLSQAEIEQKIKEYNAQIN
:: .::: . ::.::: ::.. .
CCDS14 YCSLDEELEDCFFTAKTTFFRNAQSKHLSKNVCKPVEETQRPPTLQEIKQKIDSYNTREK
20 30 40 50 60 70
150 160 170 180 190 200
pF1KB6 SNLFMSLNKDGSYTGFIKVQLKLVRPVSVPSSKKPPSLQDARRGPGRGTSVRRRTSFYLP
. : :.:..::.:::::::.::: :::.::.. .: :. :: . . .... .:::::::
CCDS14 NCLGMKLSEDGTYTGFIKVHLKLRRPVTVPAGIRPQSIYDAIKEVNLAATTDKRTSFYLP
80 90 100 110 120 130
210 220 230 240 250 260
pF1KB6 KDAVKHLHVLSRTRAREVIEALLRKFLVVDDPRKFALFERAERHGQVYLRKLLDDEQPLR
::.:.::. : : . :::..::.::.:::.:.:::::.: .. ::: ..:: ..::
CCDS14 LDAIKQLHISSTTTVSEVIQGLLKKFMVVDNPQKFALFKRIHKDGQVLFQKLSIADRPLY
140 150 160 170 180 190
270 280 290 300 310 320
pF1KB6 LRLLAGPSDKALSFVLKENDSGEVNWDAFSMPELHNFLRILQREEEEHLRQILQKYSYCR
:::::::. ..::::::::..:::.:::::.:::.::: ::..::.....:. .::. :
CCDS14 LRLLAGPDTEVLSFVLKENETGEVEWDAFSIPELQNFLTILEKEEQDKIQQVQKKYDKFR
200 210 220 230 240 250
330 340
pF1KB6 QKIQEALHACPLG
::..:::
CCDS14 QKLEEALRESQGKPG
260
>>CCDS1463.1 RASSF5 gene_id:83593|Hs108|chr1 (336 aa)
initn: 614 init1: 440 opt: 628 Z-score: 675.4 bits: 133.4 E(32554): 2.7e-31
Smith-Waterman score: 628; 44.8% identity (67.2% similar) in 259 aa overlap (11-254:81-330)
10 20 30 40
pF1KB6 MSGEPELIELRELAPAGRAGKGRTRLERANALRIARGTAC
: : : : . : : : : .:.
CCDS14 STAPGAREGRSARRAARGNLEPPPRASRPARPLRP-GLQQRLRRR-PGAPRPRDVRSIFE
60 70 80 90 100
50 60 70 80 90
pF1KB6 NPTRQLVP---GRGHRFQ----PAGPATHTWCDLCGDFIWGVVRKGLQCAHCKFTCHYRC
.: :: :.:: : :.::. :::::: :.:..:.:..:::::: .:
CCDS14 QPQDPRVPAERGEGHCFAELVLPGGPG---WCDLCGRE---VLRQALRCTNCKFTCHPEC
110 120 130 140 150 160
100 110 120 130 140
pF1KB6 RALVCLDCCGPRDLGWE-PAVER------DTNVDEPVEW-ETPDLSQAEIEQKIKEYNAQ
:.:. ::: . :. . :. : . :: .::: . : : ::.::: ::..
CCDS14 RSLIQLDCSQQEGLSRDRPSPESTLTVTFSQNVCKPVEETQRPPTLQ-EIKQKIDSYNTR
170 180 190 200 210 220
150 160 170 180 190 200
pF1KB6 INSNLFMSLNKDGSYTGFIKVQLKLVRPVSVPSSKKPPSLQDARRGPGRGTSVRRRTSFY
.. : :.:..::.:::::::.::: :::.::.. .: :. :: . . .... .:::::
CCDS14 EKNCLGMKLSEDGTYTGFIKVHLKLRRPVTVPAGIRPQSIYDAIKEVNLAATTDKRTSFY
230 240 250 260 270 280
210 220 230 240 250 260
pF1KB6 LPKDAVKHLHVLSRTRAREVIEALLRKFLVVDDPRKFALFERAERHGQVYLRKLLDDEQP
:: ::.:.::. : : . :::..::.::.:::.:.:::::.: .. :::
CCDS14 LPLDAIKQLHISSTTTVSEVIQGLLKKFMVVDNPQKFALFKRIHKDGQVGCLLHP
290 300 310 320 330
270 280 290 300 310 320
pF1KB6 LRLRLLAGPSDKALSFVLKENDSGEVNWDAFSMPELHNFLRILQREEEEHLRQILQKYSY
>>CCDS8969.1 RASSF3 gene_id:283349|Hs108|chr12 (238 aa)
initn: 570 init1: 269 opt: 430 Z-score: 466.3 bits: 94.2 E(32554): 1.2e-19
Smith-Waterman score: 539; 45.0% identity (71.2% similar) in 222 aa overlap (115-334:33-231)
90 100 110 120 130 140
pF1KB6 CKFTCHYRCRALVCLDCCGPRDLGWEPAVERDTNVDEPVEWETPD-LSQAEIEQKIKEYN
:. . : : :: . ::. ::..:...::
CCDS89 SGYSSLEEDAEDFFFTARTSFFRRAPQGKPRSGQQDVEKEKETHSYLSKEEIKEKVHKYN
10 20 30 40 50 60
150 160 170 180 190 200
pF1KB6 AQINSNLFMSLNKDGSYTGFIKVQLKLVRPVSV-PSSKKPPSLQDARRGPGRGTSVRRRT
....: :.::..: ::::::::..: .: .. :.: : :. . :
CCDS89 LAVTDKLKMTLNSNGIYTGFIKVQMELCKPPQTSPNSGK---LSPSSNG-----------
70 80 90 100
210 220 230 240 250 260
pF1KB6 SFYLPKDAVKHLHVLSRTRAREVIEALLRKFLVVDDPRKFALFERAERHGQVYLRKLLDD
.. ::. : . . :::::::.::::...: ::::..: .:. ::: :: :
CCDS89 -------CMNTLHISSTNTVGEVIEALLKKFLVTESPAKFALYKRCHREDQVYACKLSDR
110 120 130 140 150 160
270 280 290 300 310 320
pF1KB6 EQPLRLRLLAGPSDKALSFVLKENDSGEVNWDAFSMPELHNFLRILQREEEEHLRQILQK
:.:: :::.::: .:::::.:.. :: :.:::.:::.::::::..::.:.:... ..
CCDS89 EHPLYLRLVAGPRTDTLSFVLREHEIGE--WEAFSLPELQNFLRILDKEEDEQLQNLKRR
170 180 190 200 210
330 340
pF1KB6 YSYCRQKIQEALHACPLG
:. :::..:::
CCDS89 YTAYRQKLEEALREVWKPD
220 230
340 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 16:43:40 2016 done: Fri Nov 4 16:43:41 2016
Total Scan time: 2.450 Total Display time: 0.010
Function used was FASTA [36.3.4 Apr, 2011]