Result of FASTA (ccds) for
pFN21AB6449
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB6449, 317 aa
1>>>pF1KB6449 317 - 317 aa - 317 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 6.4351+/-0.000914; mu= 10.8753+/- 0.054
mean_var=124.7155+/-25.087, 0's: 0 Z-trim(109.9): 174 B-trim: 10 in 1/50
Lambda= 0.114846
statistics sampled from 10993 (11188) to 10993 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.714), E-opt: 0.2 (0.344), width: 16
Scan time: 2.770
The best scores are: opt bits E(32554)
CCDS9656.1 NFKBIA gene_id:4792|Hs108|chr14 ( 317) 2141 365.8 2.5e-101
CCDS34463.1 NFKBIE gene_id:4794|Hs108|chr6 ( 500) 483 91.2 1.8e-18
CCDS54783.1 NFKB1 gene_id:4790|Hs108|chr4 ( 968) 458 87.4 5.1e-17
CCDS3657.1 NFKB1 gene_id:4790|Hs108|chr4 ( 969) 458 87.4 5.1e-17
CCDS41565.1 NFKB2 gene_id:4791|Hs108|chr10 ( 899) 396 77.1 5.9e-14
CCDS41564.1 NFKB2 gene_id:4791|Hs108|chr10 ( 900) 396 77.1 5.9e-14
CCDS12642.2 BCL3 gene_id:602|Hs108|chr19 ( 454) 363 71.3 1.6e-12
>>CCDS9656.1 NFKBIA gene_id:4792|Hs108|chr14 (317 aa)
initn: 2141 init1: 2141 opt: 2141 Z-score: 1932.6 bits: 365.8 E(32554): 2.5e-101
Smith-Waterman score: 2141; 100.0% identity (100.0% similar) in 317 aa overlap (1-317:1-317)
10 20 30 40 50 60
pF1KB6 MFQAAERPQEWAMEGPRDGLKKERLLDDRHDSGLDSMKDEEYEQMVKELQEIRLEPQEVP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS96 MFQAAERPQEWAMEGPRDGLKKERLLDDRHDSGLDSMKDEEYEQMVKELQEIRLEPQEVP
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB6 RGSEPWKQQLTEDGDSFLHLAIIHEEKALTMEVIRQVKGDLAFLNFQNNLQQTPLHLAVI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS96 RGSEPWKQQLTEDGDSFLHLAIIHEEKALTMEVIRQVKGDLAFLNFQNNLQQTPLHLAVI
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB6 TNQPEIAEALLGAGCDPELRDFRGNTPLHLACEQGCLASVGVLTQSCTTPHLHSILKATN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS96 TNQPEIAEALLGAGCDPELRDFRGNTPLHLACEQGCLASVGVLTQSCTTPHLHSILKATN
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB6 YNGHTCLHLASIHGYLGIVELLVSLGADVNAQEPCNGRTALHLAVDLQNPDLVSLLLKCG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS96 YNGHTCLHLASIHGYLGIVELLVSLGADVNAQEPCNGRTALHLAVDLQNPDLVSLLLKCG
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB6 ADVNRVTYQGYSPYQLTWGRPSTRIQQQLGQLTLENLQMLPESEDEESYDTESEFTEFTE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS96 ADVNRVTYQGYSPYQLTWGRPSTRIQQQLGQLTLENLQMLPESEDEESYDTESEFTEFTE
250 260 270 280 290 300
310
pF1KB6 DELPYDDCVFGGQRLTL
:::::::::::::::::
CCDS96 DELPYDDCVFGGQRLTL
310
>>CCDS34463.1 NFKBIE gene_id:4794|Hs108|chr6 (500 aa)
initn: 457 init1: 237 opt: 483 Z-score: 445.3 bits: 91.2 E(32554): 1.8e-18
Smith-Waterman score: 483; 37.6% identity (65.6% similar) in 250 aa overlap (70-315:255-496)
40 50 60 70 80 90
pF1KB6 EEYEQMVKELQEIRLEPQEVPRGSEPWKQQLTEDGDSFLHLAIIHEEKALTMEVIRQVKG
..::::...:::.::: :. . . .
CCDS34 GGPEAEDPAPRLPLPHVGALSPQQLEALTYISEDGDTLVHLAVIHEAPAVLLCCLALLPQ
230 240 250 260 270 280
100 110 120 130 140 150
pF1KB6 DLAFLNFQNNLQQTPLHLAVITNQPEIAEALLGAGCDPELRDFRGNTPLHLACEQGCLAS
.. :..:::: :: ::::: .:: ..::. : . :.: .:.: ::.::.. ::
CCDS34 EV--LDIQNNLYQTALHLAVHLDQPGAVRALVLKGASRALQDRHGDTALHVACQRQHLAC
290 300 310 320 330 340
160 170 180 190 200 210
pF1KB6 VGVLTQSCTTPHL---HSI-LKATNYNGHTCLHLASIHGYLGIVELLVSLGADVNAQEPC
. : .. : ::. :. :..: .:::.:... ..:::. :::...::
CCDS34 ARCLLEGRPEPGRGTSHSLDLQLQNWQGLACLHIATLQKNQPLMELLLRNGADIDVQEGT
350 360 370 380 390 400
220 230 240 250 260 270
pF1KB6 NGRTALHLAVDLQNPDLVSLLLKCGADVNRVTYQGYSPYQLTWGRPSTRIQQQLGQLTLE
.:.:::::::. :. ::..::. ::.:. .: .: .:. :: :.. : . .
CCDS34 SGKTALHLAVETQERGLVQFLLQAGAQVDARMLNGCTPLHLAAGRGLMGISSTLCKAGAD
410 420 430 440 450 460
280 290 300 310
pF1KB6 NLQMLPESEDEESYDTESEFTEFTEDELPYDDCVFGGQRLTL
.: : . ::: : ...:: . ::.:: ..:. :
CCDS34 SL--LRNVEDE----TPQDLTEESLVLLPFDDLKISGKLLLCTD
470 480 490 500
>>CCDS54783.1 NFKB1 gene_id:4790|Hs108|chr4 (968 aa)
initn: 434 init1: 164 opt: 458 Z-score: 419.1 bits: 87.4 E(32554): 5.1e-17
Smith-Waterman score: 458; 40.9% identity (65.1% similar) in 235 aa overlap (72-302:541-767)
50 60 70 80 90 100
pF1KB6 YEQMVKELQEIRLEPQEVPRGSEPWKQQLTEDGDSFLHLAIIHEEKALTMEVIRQVKGDL
:.::: ::::::: .. :. .... ..: .
CCDS54 RHANALFDYAVTGDVKMLLAVQRHLTAVQDENGDSVLHLAIIHLHSQLVRDLLEVTSGLI
520 530 540 550 560 570
110 120 130 140 150
pF1KB6 A--FLNFQNNLQQTPLHLAVITNQPEIAEALLGAGCDPELRDFRGNTPLHLACEQGCLAS
. ..:..:.: ::::::::::.: ...: :: :: : : : ::. :::: ..:
CCDS54 SDDIINMRNDLYQTPLHLAVITKQEDVVEDLLRAGADLSLLDRLGNSVLHLAAKEGHDKV
580 590 600 610 620 630
160 170 180 190 200 210
pF1KB6 VGVLTQSCTTPHLHSILKATNYNGHTCLHLASIHGYLGIVELLVSLGADVNAQEPCNGRT
...: . . : : : .: . .::: . . : . :::. :::::::: .:::
CCDS54 LSILLKHKKAALL---LDHPNGDGLNAIHLAMMSNSLPCLLLLVAAGADVNAQEQKSGRT
640 650 660 670 680
220 230 240 250 260 270
pF1KB6 ALHLAVDLQNPDLVS-LLLKCGADVNRVTYQGYSPYQLTWGRPSTRIQQQLGQLTLENLQ
::::::. .: .:.. :::. : :. .::.: .: ... :: :::. : .
CCDS54 ALHLAVEHDNISLAGCLLLEGDAHVDSTTYDGTTPLHIAAGRGSTRLAALLKAAGAD---
690 700 710 720 730 740
280 290 300 310
pF1KB6 MLPESEDEES-YDTESEFTEFTEDELPYDDCVFGGQRLTL
: :. : :: .. . . :::
CCDS54 --PLVENFEPLYDLDDSWENAGEDEGVVPGTTPLDMATSWQVFDILNGKPYEPEFTSDDL
750 760 770 780 790 800
>>CCDS3657.1 NFKB1 gene_id:4790|Hs108|chr4 (969 aa)
initn: 434 init1: 164 opt: 458 Z-score: 419.1 bits: 87.4 E(32554): 5.1e-17
Smith-Waterman score: 458; 40.9% identity (65.1% similar) in 235 aa overlap (72-302:542-768)
50 60 70 80 90 100
pF1KB6 YEQMVKELQEIRLEPQEVPRGSEPWKQQLTEDGDSFLHLAIIHEEKALTMEVIRQVKGDL
:.::: ::::::: .. :. .... ..: .
CCDS36 RHANALFDYAVTGDVKMLLAVQRHLTAVQDENGDSVLHLAIIHLHSQLVRDLLEVTSGLI
520 530 540 550 560 570
110 120 130 140 150
pF1KB6 A--FLNFQNNLQQTPLHLAVITNQPEIAEALLGAGCDPELRDFRGNTPLHLACEQGCLAS
. ..:..:.: ::::::::::.: ...: :: :: : : : ::. :::: ..:
CCDS36 SDDIINMRNDLYQTPLHLAVITKQEDVVEDLLRAGADLSLLDRLGNSVLHLAAKEGHDKV
580 590 600 610 620 630
160 170 180 190 200 210
pF1KB6 VGVLTQSCTTPHLHSILKATNYNGHTCLHLASIHGYLGIVELLVSLGADVNAQEPCNGRT
...: . . : : : .: . .::: . . : . :::. :::::::: .:::
CCDS36 LSILLKHKKAALL---LDHPNGDGLNAIHLAMMSNSLPCLLLLVAAGADVNAQEQKSGRT
640 650 660 670 680
220 230 240 250 260 270
pF1KB6 ALHLAVDLQNPDLVS-LLLKCGADVNRVTYQGYSPYQLTWGRPSTRIQQQLGQLTLENLQ
::::::. .: .:.. :::. : :. .::.: .: ... :: :::. : .
CCDS36 ALHLAVEHDNISLAGCLLLEGDAHVDSTTYDGTTPLHIAAGRGSTRLAALLKAAGAD---
690 700 710 720 730 740
280 290 300 310
pF1KB6 MLPESEDEES-YDTESEFTEFTEDELPYDDCVFGGQRLTL
: :. : :: .. . . :::
CCDS36 --PLVENFEPLYDLDDSWENAGEDEGVVPGTTPLDMATSWQVFDILNGKPYEPEFTSDDL
750 760 770 780 790 800
>>CCDS41565.1 NFKB2 gene_id:4791|Hs108|chr10 (899 aa)
initn: 385 init1: 178 opt: 396 Z-score: 364.0 bits: 77.1 E(32554): 5.9e-14
Smith-Waterman score: 399; 37.8% identity (63.4% similar) in 238 aa overlap (72-297:486-721)
50 60 70 80 90
pF1KB6 YEQMVKELQEIRLEPQEVPRGSEPWKQQLTEDGDSFLHLAIIHEEKALTMEVIRQVKG--
:.::. ::::::: . .. ... ..
CCDS41 RSARALLDYGVTADARALLAGQRHLLTAQDENGDTPLHLAIIHGQTSVIEQIVYVIHHAQ
460 470 480 490 500 510
100 110 120 130 140 150
pF1KB6 DLAFLNFQNNLQQTPLHLAVITNQPEIAEALLGAGCDPELRDFRGNTPLHLACEQGCLAS
::. .:. :.:.::::::::::.: .. :: .: :: : : .:.. .::: . : :
CCDS41 DLGVVNLTNHLHQTPLHLAVITGQTSVVSFLLRVGADPALLDRHGDSAMHLALRAGAGAP
520 530 540 550 560 570
160 170 180 190 200 210
pF1KB6 --VGVLTQSCTTPHLHSILKATNYNGHTCLHLASIHGYLGIVELLVSLGADVNAQEPCNG
. .: :: .: . ..:. ...: .::: ..:::. ::.:.: : .:
CCDS41 ELLRALLQS-GAPAVPQLLHMPDFEGLYPVHLAVRARSPECLDLLVDSGAEVEATERQGG
580 590 600 610 620 630
220 230 240 250 260 270
pF1KB6 RTALHLAVDLQNPDLVS-LLLKCGADVNRVTYQGYSPYQLT--WGRPS-TRIQQQLG-QL
:::::::..... ::. :. : :.:: :. : .: .:. : :. ::. . : ..
CCDS41 RTALHLATEMEELGLVTHLVTKLRANVNARTFAGNTPLHLAAGLGYPTLTRLLLKAGADI
640 650 660 670 680 690
280 290 300 310
pF1KB6 TLEN---LQMLPESEDEESYDTESEFTEFTEDELPYDDCVFGGQRLTL
:: : :: .: :..:: :
CCDS41 HAENEEPLCPLPSPPTSDS-DSDSEGPEKDTRSSFRGHTPLDLTCSTKVKTLLLNAAQNT
700 710 720 730 740 750
>>CCDS41564.1 NFKB2 gene_id:4791|Hs108|chr10 (900 aa)
initn: 385 init1: 178 opt: 396 Z-score: 364.0 bits: 77.1 E(32554): 5.9e-14
Smith-Waterman score: 399; 37.8% identity (63.4% similar) in 238 aa overlap (72-297:486-721)
50 60 70 80 90
pF1KB6 YEQMVKELQEIRLEPQEVPRGSEPWKQQLTEDGDSFLHLAIIHEEKALTMEVIRQVKG--
:.::. ::::::: . .. ... ..
CCDS41 RSARALLDYGVTADARALLAGQRHLLTAQDENGDTPLHLAIIHGQTSVIEQIVYVIHHAQ
460 470 480 490 500 510
100 110 120 130 140 150
pF1KB6 DLAFLNFQNNLQQTPLHLAVITNQPEIAEALLGAGCDPELRDFRGNTPLHLACEQGCLAS
::. .:. :.:.::::::::::.: .. :: .: :: : : .:.. .::: . : :
CCDS41 DLGVVNLTNHLHQTPLHLAVITGQTSVVSFLLRVGADPALLDRHGDSAMHLALRAGAGAP
520 530 540 550 560 570
160 170 180 190 200 210
pF1KB6 --VGVLTQSCTTPHLHSILKATNYNGHTCLHLASIHGYLGIVELLVSLGADVNAQEPCNG
. .: :: .: . ..:. ...: .::: ..:::. ::.:.: : .:
CCDS41 ELLRALLQS-GAPAVPQLLHMPDFEGLYPVHLAVRARSPECLDLLVDSGAEVEATERQGG
580 590 600 610 620 630
220 230 240 250 260 270
pF1KB6 RTALHLAVDLQNPDLVS-LLLKCGADVNRVTYQGYSPYQLT--WGRPS-TRIQQQLG-QL
:::::::..... ::. :. : :.:: :. : .: .:. : :. ::. . : ..
CCDS41 RTALHLATEMEELGLVTHLVTKLRANVNARTFAGNTPLHLAAGLGYPTLTRLLLKAGADI
640 650 660 670 680 690
280 290 300 310
pF1KB6 TLEN---LQMLPESEDEESYDTESEFTEFTEDELPYDDCVFGGQRLTL
:: : :: .: :..:: :
CCDS41 HAENEEPLCPLPSPPTSDS-DSDSEGPEKDTRSSFRGHTPLDLTCSTKVKTLLLNAAQNT
700 710 720 730 740 750
>>CCDS12642.2 BCL3 gene_id:602|Hs108|chr19 (454 aa)
initn: 363 init1: 211 opt: 363 Z-score: 338.4 bits: 71.3 E(32554): 1.6e-12
Smith-Waterman score: 363; 35.9% identity (62.1% similar) in 206 aa overlap (56-260:116-319)
30 40 50 60 70 80
pF1KB6 LDDRHDSGLDSMKDEEYEQMVKELQEIRLEPQEVPRGSE-PWKQQLTEDGDSFLHLAIIH
:.: : ... . ::::. ::.:...
CCDS12 GALLPLYPTRAMGSPFPLVNLPTPLYPMMCPMEHPLSADIAMATRADEDGDTPLHIAVVQ
90 100 110 120 130 140
90 100 110 120 130 140
pF1KB6 EEKALTMEVIRQVKGDLAFLNFQNNLQQTPLHLAVITNQPEIAEALLGAGCDPELRDFRG
. . ... . :.. :::.::::::::::. : ... :. :: .: : .:
CCDS12 GNLPAVHRLVNLFQQGGRELDIYNNLRQTPLHLAVITTLPSVVRLLVTAGASPMALDRHG
150 160 170 180 190 200
150 160 170 180 190 200
pF1KB6 NTPLHLACEQGCLASVGVLTQSCTTPHLHSILKATNYNGHTCLHLASIHGYLGIVELLVS
.: :::::. . . .: .: . : :.: ::.: : ::.: :.::.
CCDS12 QTAAHLACEHRSPTCLRALLDSAAPGTLD--LEARNYDGLTALHVAVNTECQETVQLLLE
210 220 230 240 250 260
210 220 230 240 250 260
pF1KB6 LGADVNAQEPCNGRTALHLAVDLQNPDLVSLLLKCGADVNRVTYQGYSPYQLTWGRPSTR
:::..: . .::. : ::. .. ..:.:::. ::.:: :.: : . . ::
CCDS12 RGADIDAVDIKSGRSPLIHAVENNSLSMVQLLLQHGANVNAQMYSGSSALHSASGRGLLP
270 280 290 300 310 320
270 280 290 300 310
pF1KB6 IQQQLGQLTLENLQMLPESEDEESYDTESEFTEFTEDELPYDDCVFGGQRLTL
CCDS12 LVRTLVRSGADSSLKNCHNDTPLMVARSRRVIDILRGKATRPASTSQPDPSPDRSANTSP
330 340 350 360 370 380
317 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 17:31:52 2016 done: Fri Nov 4 17:31:52 2016
Total Scan time: 2.770 Total Display time: 0.010
Function used was FASTA [36.3.4 Apr, 2011]