Result of FASTA (omim) for
pFN21AB3641
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB3641, 314 aa
1>>>pF1KB3641 314 - 314 aa - 314 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 8.5826+/-0.000401; mu= 0.0380+/- 0.025
mean_var=173.8363+/-34.362, 0's: 0 Z-trim(117.2): 55 B-trim: 48 in 1/52
Lambda= 0.097276
statistics sampled from 28915 (28970) to 28915 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.681), E-opt: 0.2 (0.34), width: 16
Scan time: 5.590
The best scores are: opt bits E(85289)
NP_001035147 (OMIM: 166490) osteopontin isoform OP ( 314) 2110 308.2 1.4e-83
NP_001238759 (OMIM: 166490) osteopontin isoform 5 ( 327) 1912 280.4 3.4e-75
XP_016864053 (OMIM: 166490) PREDICTED: osteopontin ( 327) 1912 280.4 3.4e-75
NP_001035149 (OMIM: 166490) osteopontin isoform OP ( 287) 1718 253.1 4.9e-67
NP_000573 (OMIM: 166490) osteopontin isoform OPN-b ( 300) 1639 242.1 1.1e-63
NP_001238758 (OMIM: 166490) osteopontin isoform 4 ( 273) 1631 240.9 2.2e-63
>>NP_001035147 (OMIM: 166490) osteopontin isoform OPN-a (314 aa)
initn: 2110 init1: 2110 opt: 2110 Z-score: 1621.3 bits: 308.2 E(85289): 1.4e-83
Smith-Waterman score: 2110; 100.0% identity (100.0% similar) in 314 aa overlap (1-314:1-314)
10 20 30 40 50 60
pF1KB3 MRIAVICFCLLGITCAIPVKQADSGSSEEKQLYNKYPDAVATWLNPDPSQKQNLLAPQNA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MRIAVICFCLLGITCAIPVKQADSGSSEEKQLYNKYPDAVATWLNPDPSQKQNLLAPQNA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB3 VSSEETNDFKQETLPSKSNESHDHMDDMDDEDDDDHVDSQDSIDSNDSDDVDDTDDSHQS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VSSEETNDFKQETLPSKSNESHDHMDDMDDEDDDDHVDSQDSIDSNDSDDVDDTDDSHQS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB3 DESHHSDESDELVTDFPTDLPATEVFTPVVPTVDTYDGRGDSVVYGLRSKSKKFRRPDIQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DESHHSDESDELVTDFPTDLPATEVFTPVVPTVDTYDGRGDSVVYGLRSKSKKFRRPDIQ
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB3 YPDATDEDITSHMESEELNGAYKAIPVAQDLNAPSDWDSRGKDSYETSQLDDQSAETHSH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YPDATDEDITSHMESEELNGAYKAIPVAQDLNAPSDWDSRGKDSYETSQLDDQSAETHSH
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB3 KQSRLYKRKANDESNEHSDVIDSQELSKVSREFHSHEFHSHEDMLVVDPKSKEEDKHLKF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KQSRLYKRKANDESNEHSDVIDSQELSKVSREFHSHEFHSHEDMLVVDPKSKEEDKHLKF
250 260 270 280 290 300
310
pF1KB3 RISHELDSASSEVN
::::::::::::::
NP_001 RISHELDSASSEVN
310
>>NP_001238759 (OMIM: 166490) osteopontin isoform 5 [Hom (327 aa)
initn: 1910 init1: 1910 opt: 1912 Z-score: 1470.9 bits: 280.4 E(85289): 3.4e-75
Smith-Waterman score: 1912; 97.3% identity (98.0% similar) in 294 aa overlap (21-314:34-327)
10 20 30 40 50
pF1KB3 MRIAVICFCLLGITCAIPVKQADSGSSEEKQLYNKYPDAVATWLNPDPSQ
: : . :.:::::::::::::::::::
NP_001 VPRSLDKKAHRVQFQLNRIKAKIELPWGSLQLDCLMKTLKELYNKYPDAVATWLNPDPSQ
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB3 KQNLLAPQNAVSSEETNDFKQETLPSKSNESHDHMDDMDDEDDDDHVDSQDSIDSNDSDD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KQNLLAPQNAVSSEETNDFKQETLPSKSNESHDHMDDMDDEDDDDHVDSQDSIDSNDSDD
70 80 90 100 110 120
120 130 140 150 160 170
pF1KB3 VDDTDDSHQSDESHHSDESDELVTDFPTDLPATEVFTPVVPTVDTYDGRGDSVVYGLRSK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VDDTDDSHQSDESHHSDESDELVTDFPTDLPATEVFTPVVPTVDTYDGRGDSVVYGLRSK
130 140 150 160 170 180
180 190 200 210 220 230
pF1KB3 SKKFRRPDIQYPDATDEDITSHMESEELNGAYKAIPVAQDLNAPSDWDSRGKDSYETSQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SKKFRRPDIQYPDATDEDITSHMESEELNGAYKAIPVAQDLNAPSDWDSRGKDSYETSQL
190 200 210 220 230 240
240 250 260 270 280 290
pF1KB3 DDQSAETHSHKQSRLYKRKANDESNEHSDVIDSQELSKVSREFHSHEFHSHEDMLVVDPK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DDQSAETHSHKQSRLYKRKANDESNEHSDVIDSQELSKVSREFHSHEFHSHEDMLVVDPK
250 260 270 280 290 300
300 310
pF1KB3 SKEEDKHLKFRISHELDSASSEVN
::::::::::::::::::::::::
NP_001 SKEEDKHLKFRISHELDSASSEVN
310 320
>>XP_016864053 (OMIM: 166490) PREDICTED: osteopontin iso (327 aa)
initn: 1910 init1: 1910 opt: 1912 Z-score: 1470.9 bits: 280.4 E(85289): 3.4e-75
Smith-Waterman score: 1912; 97.3% identity (98.0% similar) in 294 aa overlap (21-314:34-327)
10 20 30 40 50
pF1KB3 MRIAVICFCLLGITCAIPVKQADSGSSEEKQLYNKYPDAVATWLNPDPSQ
: : . :.:::::::::::::::::::
XP_016 VPRSLDKKAHRVQFQLNRIKAKIELPWGSLQLDCLMKTLKELYNKYPDAVATWLNPDPSQ
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB3 KQNLLAPQNAVSSEETNDFKQETLPSKSNESHDHMDDMDDEDDDDHVDSQDSIDSNDSDD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KQNLLAPQNAVSSEETNDFKQETLPSKSNESHDHMDDMDDEDDDDHVDSQDSIDSNDSDD
70 80 90 100 110 120
120 130 140 150 160 170
pF1KB3 VDDTDDSHQSDESHHSDESDELVTDFPTDLPATEVFTPVVPTVDTYDGRGDSVVYGLRSK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VDDTDDSHQSDESHHSDESDELVTDFPTDLPATEVFTPVVPTVDTYDGRGDSVVYGLRSK
130 140 150 160 170 180
180 190 200 210 220 230
pF1KB3 SKKFRRPDIQYPDATDEDITSHMESEELNGAYKAIPVAQDLNAPSDWDSRGKDSYETSQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SKKFRRPDIQYPDATDEDITSHMESEELNGAYKAIPVAQDLNAPSDWDSRGKDSYETSQL
190 200 210 220 230 240
240 250 260 270 280 290
pF1KB3 DDQSAETHSHKQSRLYKRKANDESNEHSDVIDSQELSKVSREFHSHEFHSHEDMLVVDPK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DDQSAETHSHKQSRLYKRKANDESNEHSDVIDSQELSKVSREFHSHEFHSHEDMLVVDPK
250 260 270 280 290 300
300 310
pF1KB3 SKEEDKHLKFRISHELDSASSEVN
::::::::::::::::::::::::
XP_016 SKEEDKHLKFRISHELDSASSEVN
310 320
>>NP_001035149 (OMIM: 166490) osteopontin isoform OPN-c (287 aa)
initn: 1718 init1: 1718 opt: 1718 Z-score: 1324.6 bits: 253.1 E(85289): 4.9e-67
Smith-Waterman score: 1855; 91.4% identity (91.4% similar) in 314 aa overlap (1-314:1-287)
10 20 30 40 50 60
pF1KB3 MRIAVICFCLLGITCAIPVKQADSGSSEEKQLYNKYPDAVATWLNPDPSQKQNLLAPQNA
::::::::::::::::::::::::::::::: ::
NP_001 MRIAVICFCLLGITCAIPVKQADSGSSEEKQ---------------------------NA
10 20 30
70 80 90 100 110 120
pF1KB3 VSSEETNDFKQETLPSKSNESHDHMDDMDDEDDDDHVDSQDSIDSNDSDDVDDTDDSHQS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VSSEETNDFKQETLPSKSNESHDHMDDMDDEDDDDHVDSQDSIDSNDSDDVDDTDDSHQS
40 50 60 70 80 90
130 140 150 160 170 180
pF1KB3 DESHHSDESDELVTDFPTDLPATEVFTPVVPTVDTYDGRGDSVVYGLRSKSKKFRRPDIQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DESHHSDESDELVTDFPTDLPATEVFTPVVPTVDTYDGRGDSVVYGLRSKSKKFRRPDIQ
100 110 120 130 140 150
190 200 210 220 230 240
pF1KB3 YPDATDEDITSHMESEELNGAYKAIPVAQDLNAPSDWDSRGKDSYETSQLDDQSAETHSH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YPDATDEDITSHMESEELNGAYKAIPVAQDLNAPSDWDSRGKDSYETSQLDDQSAETHSH
160 170 180 190 200 210
250 260 270 280 290 300
pF1KB3 KQSRLYKRKANDESNEHSDVIDSQELSKVSREFHSHEFHSHEDMLVVDPKSKEEDKHLKF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KQSRLYKRKANDESNEHSDVIDSQELSKVSREFHSHEFHSHEDMLVVDPKSKEEDKHLKF
220 230 240 250 260 270
310
pF1KB3 RISHELDSASSEVN
::::::::::::::
NP_001 RISHELDSASSEVN
280
>>NP_000573 (OMIM: 166490) osteopontin isoform OPN-b pre (300 aa)
initn: 1627 init1: 1627 opt: 1639 Z-score: 1264.4 bits: 242.1 E(85289): 1.1e-63
Smith-Waterman score: 1986; 95.5% identity (95.5% similar) in 314 aa overlap (1-314:1-300)
10 20 30 40 50 60
pF1KB3 MRIAVICFCLLGITCAIPVKQADSGSSEEKQLYNKYPDAVATWLNPDPSQKQNLLAPQNA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 MRIAVICFCLLGITCAIPVKQADSGSSEEKQLYNKYPDAVATWLNPDPSQKQNLLAPQ--
10 20 30 40 50
70 80 90 100 110 120
pF1KB3 VSSEETNDFKQETLPSKSNESHDHMDDMDDEDDDDHVDSQDSIDSNDSDDVDDTDDSHQS
::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 ------------TLPSKSNESHDHMDDMDDEDDDDHVDSQDSIDSNDSDDVDDTDDSHQS
60 70 80 90 100
130 140 150 160 170 180
pF1KB3 DESHHSDESDELVTDFPTDLPATEVFTPVVPTVDTYDGRGDSVVYGLRSKSKKFRRPDIQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 DESHHSDESDELVTDFPTDLPATEVFTPVVPTVDTYDGRGDSVVYGLRSKSKKFRRPDIQ
110 120 130 140 150 160
190 200 210 220 230 240
pF1KB3 YPDATDEDITSHMESEELNGAYKAIPVAQDLNAPSDWDSRGKDSYETSQLDDQSAETHSH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 YPDATDEDITSHMESEELNGAYKAIPVAQDLNAPSDWDSRGKDSYETSQLDDQSAETHSH
170 180 190 200 210 220
250 260 270 280 290 300
pF1KB3 KQSRLYKRKANDESNEHSDVIDSQELSKVSREFHSHEFHSHEDMLVVDPKSKEEDKHLKF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 KQSRLYKRKANDESNEHSDVIDSQELSKVSREFHSHEFHSHEDMLVVDPKSKEEDKHLKF
230 240 250 260 270 280
310
pF1KB3 RISHELDSASSEVN
::::::::::::::
NP_000 RISHELDSASSEVN
290 300
>>NP_001238758 (OMIM: 166490) osteopontin isoform 4 prec (273 aa)
initn: 1630 init1: 1630 opt: 1631 Z-score: 1258.9 bits: 240.9 E(85289): 2.2e-63
Smith-Waterman score: 1741; 86.9% identity (86.9% similar) in 314 aa overlap (1-314:1-273)
10 20 30 40 50 60
pF1KB3 MRIAVICFCLLGITCAIPVKQADSGSSEEKQLYNKYPDAVATWLNPDPSQKQNLLAPQNA
:::::::::::::::::::::::::::::::
NP_001 MRIAVICFCLLGITCAIPVKQADSGSSEEKQ-----------------------------
10 20 30
70 80 90 100 110 120
pF1KB3 VSSEETNDFKQETLPSKSNESHDHMDDMDDEDDDDHVDSQDSIDSNDSDDVDDTDDSHQS
::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ------------TLPSKSNESHDHMDDMDDEDDDDHVDSQDSIDSNDSDDVDDTDDSHQS
40 50 60 70
130 140 150 160 170 180
pF1KB3 DESHHSDESDELVTDFPTDLPATEVFTPVVPTVDTYDGRGDSVVYGLRSKSKKFRRPDIQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DESHHSDESDELVTDFPTDLPATEVFTPVVPTVDTYDGRGDSVVYGLRSKSKKFRRPDIQ
80 90 100 110 120 130
190 200 210 220 230 240
pF1KB3 YPDATDEDITSHMESEELNGAYKAIPVAQDLNAPSDWDSRGKDSYETSQLDDQSAETHSH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YPDATDEDITSHMESEELNGAYKAIPVAQDLNAPSDWDSRGKDSYETSQLDDQSAETHSH
140 150 160 170 180 190
250 260 270 280 290 300
pF1KB3 KQSRLYKRKANDESNEHSDVIDSQELSKVSREFHSHEFHSHEDMLVVDPKSKEEDKHLKF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KQSRLYKRKANDESNEHSDVIDSQELSKVSREFHSHEFHSHEDMLVVDPKSKEEDKHLKF
200 210 220 230 240 250
310
pF1KB3 RISHELDSASSEVN
::::::::::::::
NP_001 RISHELDSASSEVN
260 270
314 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sat Nov 5 00:58:19 2016 done: Sat Nov 5 00:58:19 2016
Total Scan time: 5.590 Total Display time: 0.010
Function used was FASTA [36.3.4 Apr, 2011]