Result of FASTA (omim) for
pFN21AE1394
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE1394, 522 aa
1>>>pF1KE1394 522 - 522 aa - 522 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 6.4636+/-0.00038; mu= 15.5223+/- 0.024
mean_var=153.9286+/-31.391, 0's: 0 Z-trim(117.8): 25 B-trim: 320 in 2/53
Lambda= 0.103375
statistics sampled from 30085 (30108) to 30085 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.694), E-opt: 0.2 (0.353), width: 16
Scan time: 10.410
The best scores are: opt bits E(85289)
NP_001192183 (OMIM: 251290,602876) occludin isofor ( 522) 3526 537.9 2.8e-152
NP_002529 (OMIM: 251290,602876) occludin isoform a ( 522) 3526 537.9 2.8e-152
NP_001192184 (OMIM: 251290,602876) occludin isofor ( 271) 1822 283.5 5.6e-76
XP_016864402 (OMIM: 251290,602876) PREDICTED: occl ( 468) 1685 263.3 1.2e-69
XP_016864403 (OMIM: 251290,602876) PREDICTED: occl ( 468) 1685 263.3 1.2e-69
XP_016882826 (OMIM: 600284) PREDICTED: RNA polymer ( 337) 247 48.7 3.3e-05
XP_016882825 (OMIM: 600284) PREDICTED: RNA polymer ( 370) 247 48.7 3.6e-05
XP_016882824 (OMIM: 600284) PREDICTED: RNA polymer ( 488) 247 48.8 4.3e-05
NP_006523 (OMIM: 600284) RNA polymerase II elongat ( 621) 247 49.0 5e-05
XP_016864732 (OMIM: 601874) PREDICTED: RNA polymer ( 455) 232 46.6 0.00019
XP_016864729 (OMIM: 601874) PREDICTED: RNA polymer ( 508) 232 46.6 0.00021
XP_016864730 (OMIM: 601874) PREDICTED: RNA polymer ( 508) 232 46.6 0.00021
XP_016864731 (OMIM: 601874) PREDICTED: RNA polymer ( 508) 232 46.6 0.00021
XP_006714638 (OMIM: 601874) PREDICTED: RNA polymer ( 585) 232 46.7 0.00023
NP_036213 (OMIM: 601874) RNA polymerase II elongat ( 640) 232 46.7 0.00024
XP_005248504 (OMIM: 610153,610572) PREDICTED: MARV ( 546) 213 43.8 0.0016
NP_001231663 (OMIM: 610153,610572) MARVEL domain-c ( 546) 213 43.8 0.0016
XP_005248502 (OMIM: 610153,610572) PREDICTED: MARV ( 558) 213 43.8 0.0016
XP_005248503 (OMIM: 610153,610572) PREDICTED: MARV ( 558) 213 43.8 0.0016
NP_001033692 (OMIM: 610153,610572) MARVEL domain-c ( 558) 213 43.8 0.0016
>>NP_001192183 (OMIM: 251290,602876) occludin isoform a (522 aa)
initn: 3526 init1: 3526 opt: 3526 Z-score: 2855.0 bits: 537.9 E(85289): 2.8e-152
Smith-Waterman score: 3526; 99.8% identity (99.8% similar) in 522 aa overlap (1-522:1-522)
10 20 30 40 50 60
pF1KE1 MSSRPLESPPPYRPDEFKPNHYAPSNDIYGGEMHVRPMLSQPAYSFYPEDEILHFYKWTS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MSSRPLESPPPYRPDEFKPNHYAPSNDIYGGEMHVRPMLSQPAYSFYPEDEILHFYKWTS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 PPGVIRILSMLIIVMCIAIFACVASTLAWDRGYGTSLLGGSVGYPYGGSGFGSYGSGYGY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PPGVIRILSMLIIVMCIAIFACVASTLAWDRGYGTSLLGGSVGYPYGGSGFGSYGSGYGY
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 GYGYGYGYGGYTDPRAAKGFMLAMAAFCFIAALVIFVTSVIRSEMSRTRRYYLSVIIVSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GYGYGYGYGGYTDPRAAKGFMLAMAAFCFIAALVIFVTSVIRSEMSRTRRYYLSVIIVSA
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 ILGIMVFIATIVYIMGVNPTAQSSGSLYGSQIYALCNQFYTPAATGLYVDQYSYHYCVVD
:::::::::::::::::::::::::::::::::::::::::::::::::::: :::::::
NP_001 ILGIMVFIATIVYIMGVNPTAQSSGSLYGSQIYALCNQFYTPAATGLYVDQYLYHYCVVD
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE1 PQEAIAIVLGFMIIVAFALIIFFAVKTRRKMDRYDKSNILWDKEHIYDEQPPNVEEWVKN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PQEAIAIVLGFMIIVAFALIIFFAVKTRRKMDRYDKSNILWDKEHIYDEQPPNVEEWVKN
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE1 VSAGTQDVPSPPSDYVERVDSPMAYSSNGKVNDKRFYPESSYKSTPVPEVVQELPLTSPV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VSAGTQDVPSPPSDYVERVDSPMAYSSNGKVNDKRFYPESSYKSTPVPEVVQELPLTSPV
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE1 DDFRQPRYSSGGNFETPSKRAPAKGRAGRSKRTEQDHYETDYTTGGESCDELEEDWIREY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DDFRQPRYSSGGNFETPSKRAPAKGRAGRSKRTEQDHYETDYTTGGESCDELEEDWIREY
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE1 PPITSDQQRQLYKRNFDTGLQEYKSLQSELDEINKELSRLDKELDDYREESEEYMAAADE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PPITSDQQRQLYKRNFDTGLQEYKSLQSELDEINKELSRLDKELDDYREESEEYMAAADE
430 440 450 460 470 480
490 500 510 520
pF1KE1 YNRLKQVKGSADYKSKKNHCKQLKSKLSHIKKMVGDYDRQKT
::::::::::::::::::::::::::::::::::::::::::
NP_001 YNRLKQVKGSADYKSKKNHCKQLKSKLSHIKKMVGDYDRQKT
490 500 510 520
>>NP_002529 (OMIM: 251290,602876) occludin isoform a [Ho (522 aa)
initn: 3526 init1: 3526 opt: 3526 Z-score: 2855.0 bits: 537.9 E(85289): 2.8e-152
Smith-Waterman score: 3526; 99.8% identity (99.8% similar) in 522 aa overlap (1-522:1-522)
10 20 30 40 50 60
pF1KE1 MSSRPLESPPPYRPDEFKPNHYAPSNDIYGGEMHVRPMLSQPAYSFYPEDEILHFYKWTS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 MSSRPLESPPPYRPDEFKPNHYAPSNDIYGGEMHVRPMLSQPAYSFYPEDEILHFYKWTS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 PPGVIRILSMLIIVMCIAIFACVASTLAWDRGYGTSLLGGSVGYPYGGSGFGSYGSGYGY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 PPGVIRILSMLIIVMCIAIFACVASTLAWDRGYGTSLLGGSVGYPYGGSGFGSYGSGYGY
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 GYGYGYGYGGYTDPRAAKGFMLAMAAFCFIAALVIFVTSVIRSEMSRTRRYYLSVIIVSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 GYGYGYGYGGYTDPRAAKGFMLAMAAFCFIAALVIFVTSVIRSEMSRTRRYYLSVIIVSA
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 ILGIMVFIATIVYIMGVNPTAQSSGSLYGSQIYALCNQFYTPAATGLYVDQYSYHYCVVD
:::::::::::::::::::::::::::::::::::::::::::::::::::: :::::::
NP_002 ILGIMVFIATIVYIMGVNPTAQSSGSLYGSQIYALCNQFYTPAATGLYVDQYLYHYCVVD
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE1 PQEAIAIVLGFMIIVAFALIIFFAVKTRRKMDRYDKSNILWDKEHIYDEQPPNVEEWVKN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 PQEAIAIVLGFMIIVAFALIIFFAVKTRRKMDRYDKSNILWDKEHIYDEQPPNVEEWVKN
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE1 VSAGTQDVPSPPSDYVERVDSPMAYSSNGKVNDKRFYPESSYKSTPVPEVVQELPLTSPV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 VSAGTQDVPSPPSDYVERVDSPMAYSSNGKVNDKRFYPESSYKSTPVPEVVQELPLTSPV
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE1 DDFRQPRYSSGGNFETPSKRAPAKGRAGRSKRTEQDHYETDYTTGGESCDELEEDWIREY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 DDFRQPRYSSGGNFETPSKRAPAKGRAGRSKRTEQDHYETDYTTGGESCDELEEDWIREY
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE1 PPITSDQQRQLYKRNFDTGLQEYKSLQSELDEINKELSRLDKELDDYREESEEYMAAADE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 PPITSDQQRQLYKRNFDTGLQEYKSLQSELDEINKELSRLDKELDDYREESEEYMAAADE
430 440 450 460 470 480
490 500 510 520
pF1KE1 YNRLKQVKGSADYKSKKNHCKQLKSKLSHIKKMVGDYDRQKT
::::::::::::::::::::::::::::::::::::::::::
NP_002 YNRLKQVKGSADYKSKKNHCKQLKSKLSHIKKMVGDYDRQKT
490 500 510 520
>>NP_001192184 (OMIM: 251290,602876) occludin isoform b (271 aa)
initn: 1822 init1: 1822 opt: 1822 Z-score: 1485.0 bits: 283.5 E(85289): 5.6e-76
Smith-Waterman score: 1822; 100.0% identity (100.0% similar) in 271 aa overlap (252-522:1-271)
230 240 250 260 270 280
pF1KE1 PAATGLYVDQYSYHYCVVDPQEAIAIVLGFMIIVAFALIIFFAVKTRRKMDRYDKSNILW
::::::::::::::::::::::::::::::
NP_001 MIIVAFALIIFFAVKTRRKMDRYDKSNILW
10 20 30
290 300 310 320 330 340
pF1KE1 DKEHIYDEQPPNVEEWVKNVSAGTQDVPSPPSDYVERVDSPMAYSSNGKVNDKRFYPESS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DKEHIYDEQPPNVEEWVKNVSAGTQDVPSPPSDYVERVDSPMAYSSNGKVNDKRFYPESS
40 50 60 70 80 90
350 360 370 380 390 400
pF1KE1 YKSTPVPEVVQELPLTSPVDDFRQPRYSSGGNFETPSKRAPAKGRAGRSKRTEQDHYETD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YKSTPVPEVVQELPLTSPVDDFRQPRYSSGGNFETPSKRAPAKGRAGRSKRTEQDHYETD
100 110 120 130 140 150
410 420 430 440 450 460
pF1KE1 YTTGGESCDELEEDWIREYPPITSDQQRQLYKRNFDTGLQEYKSLQSELDEINKELSRLD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YTTGGESCDELEEDWIREYPPITSDQQRQLYKRNFDTGLQEYKSLQSELDEINKELSRLD
160 170 180 190 200 210
470 480 490 500 510 520
pF1KE1 KELDDYREESEEYMAAADEYNRLKQVKGSADYKSKKNHCKQLKSKLSHIKKMVGDYDRQK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KELDDYREESEEYMAAADEYNRLKQVKGSADYKSKKNHCKQLKSKLSHIKKMVGDYDRQK
220 230 240 250 260 270
pF1KE1 T
:
NP_001 T
>>XP_016864402 (OMIM: 251290,602876) PREDICTED: occludin (468 aa)
initn: 1662 init1: 1662 opt: 1685 Z-score: 1371.7 bits: 263.3 E(85289): 1.2e-69
Smith-Waterman score: 3046; 89.5% identity (89.5% similar) in 522 aa overlap (1-522:1-468)
10 20 30 40 50 60
pF1KE1 MSSRPLESPPPYRPDEFKPNHYAPSNDIYGGEMHVRPMLSQPAYSFYPEDEILHFYKWTS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MSSRPLESPPPYRPDEFKPNHYAPSNDIYGGEMHVRPMLSQPAYSFYPEDEILHFYKWTS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 PPGVIRILSMLIIVMCIAIFACVASTLAWDRGYGTSLLGGSVGYPYGGSGFGSYGSGYGY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PPGVIRILSMLIIVMCIAIFACVASTLAWDRGYGTSLLGGSVGYPYGGSGFGSYGSGYGY
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 GYGYGYGYGGYTDPRAAKGFMLAMAAFCFIAALVIFVTSVIRSEMSRTRRYYLSVIIVSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GYGYGYGYGGYTDPRAAKGFMLAMAAFCFIAALVIFVTSVIRSEMSRTRRYYLSVIIVSA
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 ILGIMVFIATIVYIMGVNPTAQSSGSLYGSQIYALCNQFYTPAATGLYVDQYSYHYCVVD
:::::::::::::::::::::::::::::::::::::::::::::::::::: :::::::
XP_016 ILGIMVFIATIVYIMGVNPTAQSSGSLYGSQIYALCNQFYTPAATGLYVDQYLYHYCVVD
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE1 PQEAIAIVLGFMIIVAFALIIFFAVKTRRKMDRYDKSNILWDKEHIYDEQPPNVEEWVKN
::: :::
XP_016 PQE------------------------------------------------------VKN
310 320 330 340 350 360
pF1KE1 VSAGTQDVPSPPSDYVERVDSPMAYSSNGKVNDKRFYPESSYKSTPVPEVVQELPLTSPV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VSAGTQDVPSPPSDYVERVDSPMAYSSNGKVNDKRFYPESSYKSTPVPEVVQELPLTSPV
250 260 270 280 290 300
370 380 390 400 410 420
pF1KE1 DDFRQPRYSSGGNFETPSKRAPAKGRAGRSKRTEQDHYETDYTTGGESCDELEEDWIREY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DDFRQPRYSSGGNFETPSKRAPAKGRAGRSKRTEQDHYETDYTTGGESCDELEEDWIREY
310 320 330 340 350 360
430 440 450 460 470 480
pF1KE1 PPITSDQQRQLYKRNFDTGLQEYKSLQSELDEINKELSRLDKELDDYREESEEYMAAADE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PPITSDQQRQLYKRNFDTGLQEYKSLQSELDEINKELSRLDKELDDYREESEEYMAAADE
370 380 390 400 410 420
490 500 510 520
pF1KE1 YNRLKQVKGSADYKSKKNHCKQLKSKLSHIKKMVGDYDRQKT
::::::::::::::::::::::::::::::::::::::::::
XP_016 YNRLKQVKGSADYKSKKNHCKQLKSKLSHIKKMVGDYDRQKT
430 440 450 460
>>XP_016864403 (OMIM: 251290,602876) PREDICTED: occludin (468 aa)
initn: 1662 init1: 1662 opt: 1685 Z-score: 1371.7 bits: 263.3 E(85289): 1.2e-69
Smith-Waterman score: 3046; 89.5% identity (89.5% similar) in 522 aa overlap (1-522:1-468)
10 20 30 40 50 60
pF1KE1 MSSRPLESPPPYRPDEFKPNHYAPSNDIYGGEMHVRPMLSQPAYSFYPEDEILHFYKWTS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MSSRPLESPPPYRPDEFKPNHYAPSNDIYGGEMHVRPMLSQPAYSFYPEDEILHFYKWTS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 PPGVIRILSMLIIVMCIAIFACVASTLAWDRGYGTSLLGGSVGYPYGGSGFGSYGSGYGY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PPGVIRILSMLIIVMCIAIFACVASTLAWDRGYGTSLLGGSVGYPYGGSGFGSYGSGYGY
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 GYGYGYGYGGYTDPRAAKGFMLAMAAFCFIAALVIFVTSVIRSEMSRTRRYYLSVIIVSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GYGYGYGYGGYTDPRAAKGFMLAMAAFCFIAALVIFVTSVIRSEMSRTRRYYLSVIIVSA
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 ILGIMVFIATIVYIMGVNPTAQSSGSLYGSQIYALCNQFYTPAATGLYVDQYSYHYCVVD
:::::::::::::::::::::::::::::::::::::::::::::::::::: :::::::
XP_016 ILGIMVFIATIVYIMGVNPTAQSSGSLYGSQIYALCNQFYTPAATGLYVDQYLYHYCVVD
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE1 PQEAIAIVLGFMIIVAFALIIFFAVKTRRKMDRYDKSNILWDKEHIYDEQPPNVEEWVKN
::: :::
XP_016 PQE------------------------------------------------------VKN
310 320 330 340 350 360
pF1KE1 VSAGTQDVPSPPSDYVERVDSPMAYSSNGKVNDKRFYPESSYKSTPVPEVVQELPLTSPV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VSAGTQDVPSPPSDYVERVDSPMAYSSNGKVNDKRFYPESSYKSTPVPEVVQELPLTSPV
250 260 270 280 290 300
370 380 390 400 410 420
pF1KE1 DDFRQPRYSSGGNFETPSKRAPAKGRAGRSKRTEQDHYETDYTTGGESCDELEEDWIREY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DDFRQPRYSSGGNFETPSKRAPAKGRAGRSKRTEQDHYETDYTTGGESCDELEEDWIREY
310 320 330 340 350 360
430 440 450 460 470 480
pF1KE1 PPITSDQQRQLYKRNFDTGLQEYKSLQSELDEINKELSRLDKELDDYREESEEYMAAADE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PPITSDQQRQLYKRNFDTGLQEYKSLQSELDEINKELSRLDKELDDYREESEEYMAAADE
370 380 390 400 410 420
490 500 510 520
pF1KE1 YNRLKQVKGSADYKSKKNHCKQLKSKLSHIKKMVGDYDRQKT
::::::::::::::::::::::::::::::::::::::::::
XP_016 YNRLKQVKGSADYKSKKNHCKQLKSKLSHIKKMVGDYDRQKT
430 440 450 460
>>XP_016882826 (OMIM: 600284) PREDICTED: RNA polymerase (337 aa)
initn: 255 init1: 148 opt: 247 Z-score: 214.4 bits: 48.7 E(85289): 3.3e-05
Smith-Waterman score: 282; 28.1% identity (59.6% similar) in 235 aa overlap (311-521:101-332)
290 300 310 320 330 340
pF1KE1 WDKEHIYDEQPPNVEEWVKNVSAGTQDVPSPPSDYVERVDSPMAYSSNGKVNDKRFYPES
:: :. .:.: :: .. : :
XP_016 KLGVPNGREALLPTPGPPASTDTLSSSTHLPPRLEPPRAHDPLADVSNDLGHSGR-DCEH
80 90 100 110 120
350 360 370 380 390
pF1KE1 SYKSTPVPEVVQELPLTSPVDDFRQPRYS-SGGNFETPSKRAPAKGRAGRSKRTEQ--DH
. ..:.: : ::: . . .:. : : .. . ::. : ::...: : :
XP_016 GEAAAPAPTVRLGLPLLTDCAQPSRPHGSPSRSKPKKKSKKHKDKERAAEDKPRAQLPDC
130 140 150 160 170 180
400 410 420 430 440
pF1KE1 YETDYTTGGESCDE-----------------LEEDWIREYPPITSDQQRQLYKRNFDTGL
. ..: : : :.. .: :.:..::: :: .:..
XP_016 APATHATPGAPADTPGLNGTCSVSSVPTSTSETPDYLLKYAAISSSEQRQSYKNDFNAEY
190 200 210 220 230 240
450 460 470 480 490
pF1KE1 QEYKSLQSELDEINKELSRLDKELDDYREESEEYMAAA----DEYNRLKQVKGSADYKSK
.::..:......:......:: .: . . :::: .. .:: ..: : ...:...
XP_016 SEYRDLHARIERITRRFTQLDAQLRQLSQGSEEYETTRGQILQEYRKIK--KTNTNYSQE
250 260 270 280 290 300
500 510 520
pF1KE1 KNHCKQLKSKLSHIKKMVGDYDRQKT
:..:. :.:::.:::.....::...
XP_016 KHRCEYLHSKLAHIKRLIAEYDQRQLQAWP
310 320 330
>>XP_016882825 (OMIM: 600284) PREDICTED: RNA polymerase (370 aa)
initn: 255 init1: 148 opt: 247 Z-score: 213.9 bits: 48.7 E(85289): 3.6e-05
Smith-Waterman score: 282; 28.1% identity (59.6% similar) in 235 aa overlap (311-521:134-365)
290 300 310 320 330 340
pF1KE1 WDKEHIYDEQPPNVEEWVKNVSAGTQDVPSPPSDYVERVDSPMAYSSNGKVNDKRFYPES
:: :. .:.: :: .. : :
XP_016 KLGVPNGREALLPTPGPPASTDTLSSSTHLPPRLEPPRAHDPLADVSNDLGHSGR-DCEH
110 120 130 140 150 160
350 360 370 380 390
pF1KE1 SYKSTPVPEVVQELPLTSPVDDFRQPRYS-SGGNFETPSKRAPAKGRAGRSKRTEQ--DH
. ..:.: : ::: . . .:. : : .. . ::. : ::...: : :
XP_016 GEAAAPAPTVRLGLPLLTDCAQPSRPHGSPSRSKPKKKSKKHKDKERAAEDKPRAQLPDC
170 180 190 200 210 220
400 410 420 430 440
pF1KE1 YETDYTTGGESCDE-----------------LEEDWIREYPPITSDQQRQLYKRNFDTGL
. ..: : : :.. .: :.:..::: :: .:..
XP_016 APATHATPGAPADTPGLNGTCSVSSVPTSTSETPDYLLKYAAISSSEQRQSYKNDFNAEY
230 240 250 260 270 280
450 460 470 480 490
pF1KE1 QEYKSLQSELDEINKELSRLDKELDDYREESEEYMAAA----DEYNRLKQVKGSADYKSK
.::..:......:......:: .: . . :::: .. .:: ..: : ...:...
XP_016 SEYRDLHARIERITRRFTQLDAQLRQLSQGSEEYETTRGQILQEYRKIK--KTNTNYSQE
290 300 310 320 330 340
500 510 520
pF1KE1 KNHCKQLKSKLSHIKKMVGDYDRQKT
:..:. :.:::.:::.....::...
XP_016 KHRCEYLHSKLAHIKRLIAEYDQRQLQAWP
350 360 370
>>XP_016882824 (OMIM: 600284) PREDICTED: RNA polymerase (488 aa)
initn: 255 init1: 148 opt: 247 Z-score: 212.4 bits: 48.8 E(85289): 4.3e-05
Smith-Waterman score: 282; 28.1% identity (59.6% similar) in 235 aa overlap (311-521:252-483)
290 300 310 320 330 340
pF1KE1 WDKEHIYDEQPPNVEEWVKNVSAGTQDVPSPPSDYVERVDSPMAYSSNGKVNDKRFYPES
:: :. .:.: :: .. : :
XP_016 KLGVPNGREALLPTPGPPASTDTLSSSTHLPPRLEPPRAHDPLADVSNDLGHSGR-DCEH
230 240 250 260 270 280
350 360 370 380 390
pF1KE1 SYKSTPVPEVVQELPLTSPVDDFRQPRYS-SGGNFETPSKRAPAKGRAGRSKRTEQ--DH
. ..:.: : ::: . . .:. : : .. . ::. : ::...: : :
XP_016 GEAAAPAPTVRLGLPLLTDCAQPSRPHGSPSRSKPKKKSKKHKDKERAAEDKPRAQLPDC
290 300 310 320 330 340
400 410 420 430 440
pF1KE1 YETDYTTGGESCDE-----------------LEEDWIREYPPITSDQQRQLYKRNFDTGL
. ..: : : :.. .: :.:..::: :: .:..
XP_016 APATHATPGAPADTPGLNGTCSVSSVPTSTSETPDYLLKYAAISSSEQRQSYKNDFNAEY
350 360 370 380 390 400
450 460 470 480 490
pF1KE1 QEYKSLQSELDEINKELSRLDKELDDYREESEEYMAAA----DEYNRLKQVKGSADYKSK
.::..:......:......:: .: . . :::: .. .:: ..: : ...:...
XP_016 SEYRDLHARIERITRRFTQLDAQLRQLSQGSEEYETTRGQILQEYRKIK--KTNTNYSQE
410 420 430 440 450
500 510 520
pF1KE1 KNHCKQLKSKLSHIKKMVGDYDRQKT
:..:. :.:::.:::.....::...
XP_016 KHRCEYLHSKLAHIKRLIAEYDQRQLQAWP
460 470 480
>>NP_006523 (OMIM: 600284) RNA polymerase II elongation (621 aa)
initn: 230 init1: 148 opt: 247 Z-score: 211.2 bits: 49.0 E(85289): 5e-05
Smith-Waterman score: 282; 28.1% identity (59.6% similar) in 235 aa overlap (311-521:385-616)
290 300 310 320 330 340
pF1KE1 WDKEHIYDEQPPNVEEWVKNVSAGTQDVPSPPSDYVERVDSPMAYSSNGKVNDKRFYPES
:: :. .:.: :: .. : :
NP_006 KLGVPNGREALLPTPGPPASTDTLSSSTHLPPRLEPPRAHDPLADVSNDLGHSGR-DCEH
360 370 380 390 400 410
350 360 370 380 390
pF1KE1 SYKSTPVPEVVQELPLTSPVDDFRQPRYS-SGGNFETPSKRAPAKGRAGRSKRTEQ--DH
. ..:.: : ::: . . .:. : : .. . ::. : ::...: : :
NP_006 GEAAAPAPTVRLGLPLLTDCAQPSRPHGSPSRSKPKKKSKKHKDKERAAEDKPRAQLPDC
420 430 440 450 460 470
400 410 420 430 440
pF1KE1 YETDYTTGGESCDE-----------------LEEDWIREYPPITSDQQRQLYKRNFDTGL
. ..: : : :.. .: :.:..::: :: .:..
NP_006 APATHATPGAPADTPGLNGTCSVSSVPTSTSETPDYLLKYAAISSSEQRQSYKNDFNAEY
480 490 500 510 520 530
450 460 470 480 490
pF1KE1 QEYKSLQSELDEINKELSRLDKELDDYREESEEYMAAA----DEYNRLKQVKGSADYKSK
.::..:......:......:: .: . . :::: .. .:: ..: : ...:...
NP_006 SEYRDLHARIERITRRFTQLDAQLRQLSQGSEEYETTRGQILQEYRKIK--KTNTNYSQE
540 550 560 570 580 590
500 510 520
pF1KE1 KNHCKQLKSKLSHIKKMVGDYDRQKT
:..:. :.:::.:::.....::...
NP_006 KHRCEYLHSKLAHIKRLIAEYDQRQLQAWP
600 610 620
>>XP_016864732 (OMIM: 601874) PREDICTED: RNA polymerase (455 aa)
initn: 238 init1: 100 opt: 232 Z-score: 200.7 bits: 46.6 E(85289): 0.00019
Smith-Waterman score: 232; 29.6% identity (65.1% similar) in 152 aa overlap (375-521:302-450)
350 360 370 380 390 400
pF1KE1 TPVPEVVQELPLTSPVDDFRQPRYSSGGNFETPSKRAPAKGRAGRSKRTEQDHYETDYTT
: :: .. . :. . . . : :.
XP_016 MSHKKSKKKSKKHKEKDQIKKHDIETIEEKEEDLKREEEIAKLNNSSPNSSGGVKEDCTA
280 290 300 310 320 330
410 420 430 440 450 460
pF1KE1 GGE-SCDELEEDWIREYPPITSDQQRQLYKRNFDTGLQEYKSLQSELDEINKELSRLDKE
. : : :: :.. .: :.: .::: :: .:.. .::..:..... . ... .:: .
XP_016 SMEPSAIELP-DYLIKYIAIVSYEQRQNYKDDFNAEYDEYRALHARMETVARRFIKLDAQ
340 350 360 370 380 390
470 480 490 500 510
pF1KE1 LDDYREESEEYMAAADE----YNRLKQVKGSADYKSKKNHCKQLKSKLSHIKKMVGDYDR
:.::. . .: :...:: .: .:. .: .:. :..::.:::...:..:.
XP_016 RKRLSPGSKEYQNVHEEVLQEYQKIKQ--SSPNYHEEKYRCEYLHNKLAHIKRLIGEFDQ
400 410 420 430 440
520
pF1KE1 QKT
:.
XP_016 QQAESWS
450
522 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sat Nov 5 19:22:49 2016 done: Sat Nov 5 19:22:50 2016
Total Scan time: 10.410 Total Display time: 0.060
Function used was FASTA [36.3.4 Apr, 2011]