Result of FASTA (omim) for
pFN21AE5408
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE5408, 336 aa
1>>>pF1KE5408 336 - 336 aa - 336 aa
Library: /omim/omim.rfq.tfa
64092750 residues in 91774 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.5826+/-0.000383; mu= 14.7039+/- 0.024
mean_var=75.0439+/-16.264, 0's: 0 Z-trim(112.4): 89 B-trim: 338 in 1/53
Lambda= 0.148053
statistics sampled from 22028 (22132) to 22028 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.598), E-opt: 0.2 (0.241), width: 16
Scan time: 3.880
The best scores are: opt bits E(91774)
NP_002236 (OMIM: 601745) potassium channel subfami ( 336) 2238 487.6 1.7e-137
XP_011542486 (OMIM: 601745) potassium channel subf ( 268) 1465 322.5 7.1e-88
NP_004814 (OMIM: 603939) potassium channel subfami ( 313) 807 181.9 1.6e-45
NP_203133 (OMIM: 603940) potassium channel subfami ( 307) 696 158.2 2.2e-38
NP_203134 (OMIM: 603940) potassium channel subfami ( 252) 583 134.0 3.5e-31
NP_258416 (OMIM: 603940) potassium channel subfami ( 252) 583 134.0 3.5e-31
NP_005705 (OMIM: 603940) potassium channel subfami ( 257) 583 134.1 3.5e-31
XP_024305396 (OMIM: 605873) potassium channel subf ( 484) 523 121.4 4.3e-27
NP_066984 (OMIM: 605873) potassium channel subfami ( 538) 523 121.4 4.7e-27
NP_612191 (OMIM: 605873) potassium channel subfami ( 543) 523 121.4 4.7e-27
NP_612190 (OMIM: 605873) potassium channel subfami ( 543) 523 121.4 4.7e-27
NP_001128578 (OMIM: 607369) potassium channel subf ( 294) 517 120.0 6.9e-27
NP_115491 (OMIM: 607369) potassium channel subfami ( 309) 517 120.0 7.2e-27
XP_011507826 (OMIM: 603219) potassium channel subf ( 370) 504 117.3 5.7e-26
XP_011507824 (OMIM: 603219) potassium channel subf ( 370) 504 117.3 5.7e-26
XP_011507825 (OMIM: 603219) potassium channel subf ( 370) 504 117.3 5.7e-26
NP_201567 (OMIM: 605720,618381) potassium channel ( 393) 504 117.3 6e-26
NP_001304019 (OMIM: 605720,618381) potassium chann ( 393) 504 117.3 6e-26
NP_055032 (OMIM: 603219) potassium channel subfami ( 411) 504 117.3 6.2e-26
XP_016856738 (OMIM: 603219) potassium channel subf ( 412) 504 117.3 6.2e-26
NP_001017424 (OMIM: 603219) potassium channel subf ( 422) 504 117.3 6.4e-26
XP_016856737 (OMIM: 603219) potassium channel subf ( 422) 504 117.3 6.4e-26
NP_001017425 (OMIM: 603219) potassium channel subf ( 426) 504 117.3 6.4e-26
NP_001128577 (OMIM: 607369) potassium channel subf ( 322) 488 113.8 5.4e-25
XP_016866835 (OMIM: 607369) potassium channel subf ( 262) 484 112.9 8.3e-25
NP_001128579 (OMIM: 607369) potassium channel subf ( 262) 484 112.9 8.3e-25
XP_005249513 (OMIM: 603493) potassium channel subf ( 496) 468 109.7 1.5e-23
NP_003731 (OMIM: 603493) potassium channel subfami ( 499) 468 109.7 1.5e-23
XP_024307556 (OMIM: 603939) potassium channel subf ( 179) 444 104.3 2.3e-22
NP_113648 (OMIM: 607370) potassium channel subfami ( 332) 417 98.7 2e-20
XP_011535142 (OMIM: 605873) potassium channel subf ( 410) 402 95.5 2.2e-19
NP_001350713 (OMIM: 607369) potassium channel subf ( 197) 376 89.8 5.8e-18
NP_002237 (OMIM: 603220,615344) potassium channel ( 394) 379 90.6 6.5e-18
NP_001128583 (OMIM: 607370) potassium channel subf ( 271) 372 89.0 1.4e-17
XP_011515404 (OMIM: 605874,612292) potassium chann ( 374) 366 87.8 4.3e-17
NP_001269463 (OMIM: 605874,612292) potassium chann ( 374) 366 87.8 4.3e-17
XP_011515403 (OMIM: 605874,612292) potassium chann ( 401) 366 87.8 4.6e-17
NP_071753 (OMIM: 607368) potassium channel subfami ( 330) 342 82.6 1.4e-15
NP_071337 (OMIM: 607367) potassium channel subfami ( 408) 273 68.0 4.4e-11
XP_016882995 (OMIM: 603939) potassium channel subf ( 185) 255 63.9 3.3e-10
XP_011525829 (OMIM: 603939) potassium channel subf ( 176) 254 63.7 3.7e-10
NP_071338 (OMIM: 607366) potassium channel subfami ( 430) 248 62.6 1.9e-09
XP_005264350 (OMIM: 603220,615344) potassium chann ( 284) 224 57.4 4.6e-08
XP_016869019 (OMIM: 605874,612292) potassium chann ( 264) 220 56.5 7.9e-08
XP_016869020 (OMIM: 605874,612292) potassium chann ( 264) 220 56.5 7.9e-08
XP_011515405 (OMIM: 605874,612292) potassium chann ( 291) 220 56.5 8.5e-08
NP_862823 (OMIM: 613655,613656) potassium channel ( 384) 202 52.8 1.5e-06
XP_006715298 (OMIM: 603493) potassium channel subf ( 317) 170 45.9 0.00015
>>NP_002236 (OMIM: 601745) potassium channel subfamily K (336 aa)
initn: 2238 init1: 2238 opt: 2238 Z-score: 2590.1 bits: 487.6 E(91774): 1.7e-137
Smith-Waterman score: 2238; 100.0% identity (100.0% similar) in 336 aa overlap (1-336:1-336)
10 20 30 40 50 60
pF1KE5 MLQSLAGSSCVRLVERHRSAWCFGFLVLGYLLYLVFGAVVFSSVELPYEDLLRQELRKLK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 MLQSLAGSSCVRLVERHRSAWCFGFLVLGYLLYLVFGAVVFSSVELPYEDLLRQELRKLK
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE5 RRFLEEHECLSEQQLEQFLGRVLEASNYGVSVLSNASGNWNWDFTSALFFASTVLSTTGY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 RRFLEEHECLSEQQLEQFLGRVLEASNYGVSVLSNASGNWNWDFTSALFFASTVLSTTGY
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE5 GHTVPLSDGGKAFCIIYSVIGIPFTLLFLTAVVQRITVHVTRRPVLYFHIRWGFSKQVVA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 GHTVPLSDGGKAFCIIYSVIGIPFTLLFLTAVVQRITVHVTRRPVLYFHIRWGFSKQVVA
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE5 IVHAVLLGFVTVSCFFFIPAAVFSVLEDDWNFLESFYFCFISLSTIGLGDYVPGEGYNQK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 IVHAVLLGFVTVSCFFFIPAAVFSVLEDDWNFLESFYFCFISLSTIGLGDYVPGEGYNQK
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE5 FRELYKIGITCYLLLGLIAMLVVLETFCELHELKKFRKMFYVKKDKDEDQVHIIEHDQLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 FRELYKIGITCYLLLGLIAMLVVLETFCELHELKKFRKMFYVKKDKDEDQVHIIEHDQLS
250 260 270 280 290 300
310 320 330
pF1KE5 FSSITDQAAGMKEDQKQNEPFVATQSSACVDGPANH
::::::::::::::::::::::::::::::::::::
NP_002 FSSITDQAAGMKEDQKQNEPFVATQSSACVDGPANH
310 320 330
>>XP_011542486 (OMIM: 601745) potassium channel subfamil (268 aa)
initn: 1465 init1: 1465 opt: 1465 Z-score: 1699.2 bits: 322.5 E(91774): 7.1e-88
Smith-Waterman score: 1465; 100.0% identity (100.0% similar) in 218 aa overlap (119-336:51-268)
90 100 110 120 130 140
pF1KE5 GVSVLSNASGNWNWDFTSALFFASTVLSTTGYGHTVPLSDGGKAFCIIYSVIGIPFTLLF
::::::::::::::::::::::::::::::
XP_011 TQDFKLNGYQLKSRKCSFPFVPWYLEECAIGYGHTVPLSDGGKAFCIIYSVIGIPFTLLF
30 40 50 60 70 80
150 160 170 180 190 200
pF1KE5 LTAVVQRITVHVTRRPVLYFHIRWGFSKQVVAIVHAVLLGFVTVSCFFFIPAAVFSVLED
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LTAVVQRITVHVTRRPVLYFHIRWGFSKQVVAIVHAVLLGFVTVSCFFFIPAAVFSVLED
90 100 110 120 130 140
210 220 230 240 250 260
pF1KE5 DWNFLESFYFCFISLSTIGLGDYVPGEGYNQKFRELYKIGITCYLLLGLIAMLVVLETFC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DWNFLESFYFCFISLSTIGLGDYVPGEGYNQKFRELYKIGITCYLLLGLIAMLVVLETFC
150 160 170 180 190 200
270 280 290 300 310 320
pF1KE5 ELHELKKFRKMFYVKKDKDEDQVHIIEHDQLSFSSITDQAAGMKEDQKQNEPFVATQSSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ELHELKKFRKMFYVKKDKDEDQVHIIEHDQLSFSSITDQAAGMKEDQKQNEPFVATQSSA
210 220 230 240 250 260
330
pF1KE5 CVDGPANH
::::::::
XP_011 CVDGPANH
>>NP_004814 (OMIM: 603939) potassium channel subfamily K (313 aa)
initn: 874 init1: 645 opt: 807 Z-score: 938.7 bits: 181.9 E(91774): 1.6e-45
Smith-Waterman score: 833; 45.5% identity (73.5% similar) in 310 aa overlap (18-309:3-310)
10 20 30 40 50 60
pF1KE5 MLQSLAGSSCVRLVERHRSAWCFGFLVLGYLLYLVFGAVVFSSVELPYEDLLRQELRKLK
:.: : :. .: :::.::.. . .: :.: :: ::. :.
NP_004 MRRGALLAGALA-AYAAYLVLGALLVARLEGPHEARLRAELETLR
10 20 30 40
70 80 90 100 110
pF1KE5 RRFLEEHECLSEQQLEQFLGRVLEASNYGVSVLSNASGNWN-----WDFTSALFFASTVL
..:.. :.. :. :. ::: :. : ::.::::. : :::.::::::::..
NP_004 AQLLQRSPCVAAPALDAFVERVLAAGRLGRVVLANASGSANASDPAWDFASALFFASTLI
50 60 70 80 90 100
120 130 140 150 160 170
pF1KE5 STTGYGHTVPLSDGGKAFCIIYSVIGIPFTLLFLTAVVQRITVHVTRRPVLYFHIRWGFS
.:.:::.:.::.:.:::: : ....:.: :.:.::: .::... .:. :. .. .:::..
NP_004 TTVGYGYTTPLTDAGKAFSIAFALLGVPTTMLLLTASAQRLSLLLTHVPLSWLSMRWGWD
110 120 130 140 150 160
180 190 200 210 220 230
pF1KE5 KQVVAIVHAV-LLGFVTVSCFFFIPAAVFSVLEDDWNFLESFYFCFISLSTIGLGDYVPG
. .: : : ::: :.. ::. .::..:. ::. :.::..:::::::::::::::::::
NP_004 PRRAACWHLVALLGVVVTVCFL-VPAVIFAHLEEAWSFLDAFYFCFISLSTIGLGDYVPG
170 180 190 200 210 220
240 250 260 270 280
pF1KE5 EGYNQKFRELYKIGITCYLLLGLIAMLVVLETFCELHELKKFRKMFYVKK------DKDE
:. .: .: :::. .: ::.:::.::..::.:: .. .:. . ... . . ::
NP_004 EAPGQPYRALYKVLVTVYLFLGLVAMVLVLQTFRHVSDLHGLTELILLPPPCPASFNADE
230 240 250 260 270 280
290 300 310 320 330
pF1KE5 D-QVHII-----EHDQLSFSSITDQAAGMKEDQKQNEPFVATQSSACVDGPANH
: .: :. :.::: :: :: :.
NP_004 DDRVDILGPQPESHQQLSASSHTDYASIPR
290 300 310
>>NP_203133 (OMIM: 603940) potassium channel subfamily K (307 aa)
initn: 593 init1: 297 opt: 696 Z-score: 810.6 bits: 158.2 E(91774): 2.2e-38
Smith-Waterman score: 696; 41.3% identity (71.3% similar) in 293 aa overlap (21-308:7-298)
10 20 30 40 50
pF1KE5 MLQSLAGSSCVRLVERHRSAWC-FGFLVLGYLLYLVFGAVVFSSVELPYEDLLRQELRKL
: .:.::...:: : .:::::...: : :. :::
NP_203 MGGLRPWSRYGLLVVAHLLALGLGAVVFQALEGPPACRLQAELRAE
10 20 30 40
60 70 80 90 100 110
pF1KE5 KRRFLEEHE-CLSEQQLEQFLGRVLEASNYGVSVLSNASGNWNWDFTSALFFASTVLSTT
: ::. :: ::..:: .: .. .:::.:.:.: . .::. :::.::...:.::
NP_203 LAAFQAEHRACLPPGALEELLGTALATQAHGVSTLGNSSEGRTWDLPSALLFAASILTTT
50 60 70 80 90 100
120 130 140 150 160 170
pF1KE5 GYGHTVPLSDGGKAFCIIYSVIGIPFTLLFLTAVVQRITVHVTRRPVLYFHIRWGFSKQV
:::: .::: ::::::..:...:.: .: :.:.... . : :: . ..: .:
NP_203 GYGHMAPLSPGGKAFCMVYAALGLPASLA-LVATLRHCLLPVLSRPRAWVAVHWQLSPAR
110 120 130 140 150 160
180 190 200 210 220 230
pF1KE5 VAIVHAVLLGFVTVSCFFFIPAAVFSVLEDDWNFLESFYFCFISLSTIGLGDYVPGEGYN
.:...:: ::....: : ..:: :. :. : ..: . :::: ::::::: : .::.: .
NP_203 AALLQAVALGLLVASSFVLLPALVLWGLQGDCSLLGAVYFCFSSLSTIGLEDLLPGRGRS
170 180 190 200 210 220
240 250 260 270 280 290
pF1KE5 QK--FRELYKIGITCYLLLGLIAMLVVLETFCELHELKKFRKMFYVKKD-KDEDQVHIIE
. . .: .... ::::::.:::...::: :: ... . :.: . ::: :.
NP_203 LHPVIYHLGQLALLGYLLLGLLAMLLAVETFSELPQVRAMGKFFRPSGPVTAEDQGGILG
230 240 250 260 270 280
300 310 320 330
pF1KE5 HDQLSFSSITDQAAGMKEDQKQNEPFVATQSSACVDGPANH
.:.:..:.. :
NP_203 QDELALSTLPPAAPASGQAPAC
290 300
>>NP_203134 (OMIM: 603940) potassium channel subfamily K (252 aa)
initn: 498 init1: 292 opt: 583 Z-score: 681.5 bits: 134.0 E(91774): 3.5e-31
Smith-Waterman score: 583; 44.0% identity (72.9% similar) in 218 aa overlap (21-236:7-223)
10 20 30 40 50
pF1KE5 MLQSLAGSSCVRLVERHRSAWC-FGFLVLGYLLYLVFGAVVFSSVELPYEDLLRQELRKL
: .:.::...:: : .:::::...: : :. :::
NP_203 MGGLRPWSRYGLLVVAHLLALGLGAVVFQALEGPPACRLQAELRAE
10 20 30 40
60 70 80 90 100 110
pF1KE5 KRRFLEEHE-CLSEQQLEQFLGRVLEASNYGVSVLSNASGNWNWDFTSALFFASTVLSTT
: ::. :: ::..:: .: .. .:::.:.:.: . .::. :::.::...:.::
NP_203 LAAFQAEHRACLPPGALEELLGTALATQAHGVSTLGNSSEGRTWDLPSALLFAASILTTT
50 60 70 80 90 100
120 130 140 150 160 170
pF1KE5 GYGHTVPLSDGGKAFCIIYSVIGIPFTLLFLTAVVQRITVHVTRRPVLYFHIRWGFSKQV
:::: .::: ::::::..:...:.: .: :.:.... . : :: . ..: .:
NP_203 GYGHMAPLSPGGKAFCMVYAALGLPASLA-LVATLRHCLLPVLSRPRAWVAVHWQLSPAR
110 120 130 140 150 160
180 190 200 210 220 230
pF1KE5 VAIVHAVLLGFVTVSCFFFIPAAVFSVLEDDWNFLESFYFCFISLSTIGLGDYVPGEGYN
.:...:: ::....: : ..:: :. :. : ..: . :::: ::::::: : .::.:
NP_203 AALLQAVALGLLVASSFVLLPALVLWGLQGDCSLLGAVYFCFSSLSTIGLEDLLPGRGRS
170 180 190 200 210 220
240 250 260 270 280 290
pF1KE5 QKFRELYKIGITCYLLLGLIAMLVVLETFCELHELKKFRKMFYVKKDKDEDQVHIIEHDQ
NP_203 LHPVIYHLGQLALLGGGTSLQGTAWEG
230 240 250
>>NP_258416 (OMIM: 603940) potassium channel subfamily K (252 aa)
initn: 498 init1: 292 opt: 583 Z-score: 681.5 bits: 134.0 E(91774): 3.5e-31
Smith-Waterman score: 583; 44.0% identity (72.9% similar) in 218 aa overlap (21-236:7-223)
10 20 30 40 50
pF1KE5 MLQSLAGSSCVRLVERHRSAWC-FGFLVLGYLLYLVFGAVVFSSVELPYEDLLRQELRKL
: .:.::...:: : .:::::...: : :. :::
NP_258 MGGLRPWSRYGLLVVAHLLALGLGAVVFQALEGPPACRLQAELRAE
10 20 30 40
60 70 80 90 100 110
pF1KE5 KRRFLEEHE-CLSEQQLEQFLGRVLEASNYGVSVLSNASGNWNWDFTSALFFASTVLSTT
: ::. :: ::..:: .: .. .:::.:.:.: . .::. :::.::...:.::
NP_258 LAAFQAEHRACLPPGALEELLGTALATQAHGVSTLGNSSEGRTWDLPSALLFAASILTTT
50 60 70 80 90 100
120 130 140 150 160 170
pF1KE5 GYGHTVPLSDGGKAFCIIYSVIGIPFTLLFLTAVVQRITVHVTRRPVLYFHIRWGFSKQV
:::: .::: ::::::..:...:.: .: :.:.... . : :: . ..: .:
NP_258 GYGHMAPLSPGGKAFCMVYAALGLPASLA-LVATLRHCLLPVLSRPRAWVAVHWQLSPAR
110 120 130 140 150 160
180 190 200 210 220 230
pF1KE5 VAIVHAVLLGFVTVSCFFFIPAAVFSVLEDDWNFLESFYFCFISLSTIGLGDYVPGEGYN
.:...:: ::....: : ..:: :. :. : ..: . :::: ::::::: : .::.:
NP_258 AALLQAVALGLLVASSFVLLPALVLWGLQGDCSLLGAVYFCFSSLSTIGLEDLLPGRGRS
170 180 190 200 210 220
240 250 260 270 280 290
pF1KE5 QKFRELYKIGITCYLLLGLIAMLVVLETFCELHELKKFRKMFYVKKDKDEDQVHIIEHDQ
NP_258 LHPVIYHLGQLALLGGGTSLQGTAWEG
230 240 250
>>NP_005705 (OMIM: 603940) potassium channel subfamily K (257 aa)
initn: 498 init1: 292 opt: 583 Z-score: 681.3 bits: 134.1 E(91774): 3.5e-31
Smith-Waterman score: 583; 44.0% identity (72.9% similar) in 218 aa overlap (21-236:7-223)
10 20 30 40 50
pF1KE5 MLQSLAGSSCVRLVERHRSAWC-FGFLVLGYLLYLVFGAVVFSSVELPYEDLLRQELRKL
: .:.::...:: : .:::::...: : :. :::
NP_005 MGGLRPWSRYGLLVVAHLLALGLGAVVFQALEGPPACRLQAELRAE
10 20 30 40
60 70 80 90 100 110
pF1KE5 KRRFLEEHE-CLSEQQLEQFLGRVLEASNYGVSVLSNASGNWNWDFTSALFFASTVLSTT
: ::. :: ::..:: .: .. .:::.:.:.: . .::. :::.::...:.::
NP_005 LAAFQAEHRACLPPGALEELLGTALATQAHGVSTLGNSSEGRTWDLPSALLFAASILTTT
50 60 70 80 90 100
120 130 140 150 160 170
pF1KE5 GYGHTVPLSDGGKAFCIIYSVIGIPFTLLFLTAVVQRITVHVTRRPVLYFHIRWGFSKQV
:::: .::: ::::::..:...:.: .: :.:.... . : :: . ..: .:
NP_005 GYGHMAPLSPGGKAFCMVYAALGLPASLA-LVATLRHCLLPVLSRPRAWVAVHWQLSPAR
110 120 130 140 150 160
180 190 200 210 220 230
pF1KE5 VAIVHAVLLGFVTVSCFFFIPAAVFSVLEDDWNFLESFYFCFISLSTIGLGDYVPGEGYN
.:...:: ::....: : ..:: :. :. : ..: . :::: ::::::: : .::.:
NP_005 AALLQAVALGLLVASSFVLLPALVLWGLQGDCSLLGAVYFCFSSLSTIGLEDLLPGRGRS
170 180 190 200 210 220
240 250 260 270 280 290
pF1KE5 QKFRELYKIGITCYLLLGLIAMLVVLETFCELHELKKFRKMFYVKKDKDEDQVHIIEHDQ
NP_005 LHPVIYHLGQLALLGKSSHLTACGGRGKRSLD
230 240 250
>>XP_024305396 (OMIM: 605873) potassium channel subfamil (484 aa)
initn: 488 init1: 193 opt: 523 Z-score: 608.0 bits: 121.4 E(91774): 4.3e-27
Smith-Waterman score: 523; 35.1% identity (71.4% similar) in 245 aa overlap (25-264:22-261)
10 20 30 40 50 60
pF1KE5 MLQSLAGSSCVRLVERHRSAWCFGFLVLGYLLYLVFGAVVFSSVELPYEDLLRQELRKLK
:.:. ..::: :..:: ..: :.:. .. . :
XP_024 MEGTSQGGLQTVMKWKTVVAIFVVV--VVYLVTGGLVFRALEQPFESSQKNTIALEK
10 20 30 40 50
70 80 90 100 110
pF1KE5 RRFLEEHECLSEQQLEQFLGRVLEASNYGVSVLSNASGNWN-WDFTSALFFASTVLSTTG
.::..: :.: :.:: .. ..:.:.: ::: ..:.:.: . ::. ::.:::.::..: :
XP_024 AEFLRDHVCVSPQELETLIQHALDADNAGVSPIGNSSNNSSHWDLGSAFFFAGTVITTIG
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE5 YGHTVPLSDGGKAFCIIYSVIGIPFTLLFLTAVVQRITVHVTRRPVLYFHI--RWGFSKQ
::. .: ..::: :::.:...:::. ..:... ... . . . .. . :.
XP_024 YGNIAPSTEGGKIFCILYAIFGIPLFGFLLAGIGDQLGTIFGKSIARVEKVFRKKQVSQT
120 130 140 150 160 170
180 190 200 210 220 230
pF1KE5 VVAIVHAVLLGFVTVSCFFF--IPAAVFSVLEDDWNFLESFYFCFISLSTIGLGDYVPGE
. .. ..: :. ..:. : :::..:. .: :. :::.:: ..:.:.:.::.: :
XP_024 KIRVISTIL--FILAGCIVFVTIPAVIFKYIEG-WTALESIYFVVVTLTTVGFGDFVAGG
180 190 200 210 220 230
240 250 260 270 280 290
pF1KE5 GYNQKFRELYKIGITCYLLLGLIAMLVVLETFCELHELKKFRKMFYVKKDKDEDQVHIIE
. . ..:: :: . ..:.:: . .::
XP_024 NAGINYREWYKPLVWFWILVGLAYFAAVLSMIGDWLRVLSKKTKEEVGEIKAHAAEWKAN
240 250 260 270 280 290
>>NP_066984 (OMIM: 605873) potassium channel subfamily K (538 aa)
initn: 488 init1: 193 opt: 523 Z-score: 607.3 bits: 121.4 E(91774): 4.7e-27
Smith-Waterman score: 523; 35.1% identity (71.4% similar) in 245 aa overlap (25-264:76-315)
10 20 30 40 50
pF1KE5 MLQSLAGSSCVRLVERHRSAWCFGFLVLGYLLYLVFGAVVFSSVELPYEDLLRQ
:.:. ..::: :..:: ..: :.:. ..
NP_066 SSRATVVARMEGTSQGGLQTVMKWKTVVAIFVVV--VVYLVTGGLVFRALEQPFESSQKN
50 60 70 80 90 100
60 70 80 90 100 110
pF1KE5 ELRKLKRRFLEEHECLSEQQLEQFLGRVLEASNYGVSVLSNASGNWN-WDFTSALFFAST
. : .::..: :.: :.:: .. ..:.:.: ::: ..:.:.: . ::. ::.:::.:
NP_066 TIALEKAEFLRDHVCVSPQELETLIQHALDADNAGVSPIGNSSNNSSHWDLGSAFFFAGT
110 120 130 140 150 160
120 130 140 150 160 170
pF1KE5 VLSTTGYGHTVPLSDGGKAFCIIYSVIGIPFTLLFLTAVVQRITVHVTRRPVLYFHI--R
:..: :::. .: ..::: :::.:...:::. ..:... ... . . . .. .
NP_066 VITTIGYGNIAPSTEGGKIFCILYAIFGIPLFGFLLAGIGDQLGTIFGKSIARVEKVFRK
170 180 190 200 210 220
180 190 200 210 220
pF1KE5 WGFSKQVVAIVHAVLLGFVTVSCFFF--IPAAVFSVLEDDWNFLESFYFCFISLSTIGLG
:. . .. ..: :. ..:. : :::..:. .: :. :::.:: ..:.:.:.:
NP_066 KQVSQTKIRVISTIL--FILAGCIVFVTIPAVIFKYIEG-WTALESIYFVVVTLTTVGFG
230 240 250 260 270 280
230 240 250 260 270 280
pF1KE5 DYVPGEGYNQKFRELYKIGITCYLLLGLIAMLVVLETFCELHELKKFRKMFYVKKDKDED
:.: : . . ..:: :: . ..:.:: . .::
NP_066 DFVAGGNAGINYREWYKPLVWFWILVGLAYFAAVLSMIGDWLRVLSKKTKEEVGEIKAHA
290 300 310 320 330 340
290 300 310 320 330
pF1KE5 QVHIIEHDQLSFSSITDQAAGMKEDQKQNEPFVATQSSACVDGPANH
NP_066 AEWKANVTAEFRETRRRLSVEIHDKLQRAATIRSMERRRLGLDQRAHSLDMLSPEKRSVF
350 360 370 380 390 400
>>NP_612191 (OMIM: 605873) potassium channel subfamily K (543 aa)
initn: 488 init1: 193 opt: 523 Z-score: 607.3 bits: 121.4 E(91774): 4.7e-27
Smith-Waterman score: 523; 35.1% identity (71.4% similar) in 245 aa overlap (25-264:81-320)
10 20 30 40 50
pF1KE5 MLQSLAGSSCVRLVERHRSAWCFGFLVLGYLLYLVFGAVVFSSVELPYEDLLRQ
:.:. ..::: :..:: ..: :.:. ..
NP_612 SSRATVVARMEGTSQGGLQTVMKWKTVVAIFVVV--VVYLVTGGLVFRALEQPFESSQKN
60 70 80 90 100
60 70 80 90 100 110
pF1KE5 ELRKLKRRFLEEHECLSEQQLEQFLGRVLEASNYGVSVLSNASGNWN-WDFTSALFFAST
. : .::..: :.: :.:: .. ..:.:.: ::: ..:.:.: . ::. ::.:::.:
NP_612 TIALEKAEFLRDHVCVSPQELETLIQHALDADNAGVSPIGNSSNNSSHWDLGSAFFFAGT
110 120 130 140 150 160
120 130 140 150 160 170
pF1KE5 VLSTTGYGHTVPLSDGGKAFCIIYSVIGIPFTLLFLTAVVQRITVHVTRRPVLYFHI--R
:..: :::. .: ..::: :::.:...:::. ..:... ... . . . .. .
NP_612 VITTIGYGNIAPSTEGGKIFCILYAIFGIPLFGFLLAGIGDQLGTIFGKSIARVEKVFRK
170 180 190 200 210 220
180 190 200 210 220
pF1KE5 WGFSKQVVAIVHAVLLGFVTVSCFFF--IPAAVFSVLEDDWNFLESFYFCFISLSTIGLG
:. . .. ..: :. ..:. : :::..:. .: :. :::.:: ..:.:.:.:
NP_612 KQVSQTKIRVISTIL--FILAGCIVFVTIPAVIFKYIEG-WTALESIYFVVVTLTTVGFG
230 240 250 260 270 280
230 240 250 260 270 280
pF1KE5 DYVPGEGYNQKFRELYKIGITCYLLLGLIAMLVVLETFCELHELKKFRKMFYVKKDKDED
:.: : . . ..:: :: . ..:.:: . .::
NP_612 DFVAGGNAGINYREWYKPLVWFWILVGLAYFAAVLSMIGDWLRVLSKKTKEEVGEIKAHA
290 300 310 320 330 340
290 300 310 320 330
pF1KE5 QVHIIEHDQLSFSSITDQAAGMKEDQKQNEPFVATQSSACVDGPANH
NP_612 AEWKANVTAEFRETRRRLSVEIHDKLQRAATIRSMERRRLGLDQRAHSLDMLSPEKRSVF
350 360 370 380 390 400
336 residues in 1 query sequences
64092750 residues in 91774 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Tue Jul 16 15:42:05 2019 done: Tue Jul 16 15:42:06 2019
Total Scan time: 3.880 Total Display time: 0.050
Function used was FASTA [36.3.4 Apr, 2011]