Result of FASTA (omim) for
pFN21AB6909
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB6909, 205 aa
1>>>pF1KB6909 205 - 205 aa - 205 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.5128+/-0.000254; mu= 14.4741+/- 0.016
mean_var=86.6344+/-17.511, 0's: 0 Z-trim(121.3): 18 B-trim: 0 in 0/56
Lambda= 0.137794
statistics sampled from 37610 (37630) to 37610 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.79), E-opt: 0.2 (0.441), width: 16
Scan time: 5.960
The best scores are: opt bits E(85289)
NP_001531 (OMIM: 602195,606595,608634) heat shock ( 205) 1405 288.0 7.4e-78
NP_055180 (OMIM: 158590,608014,608673) heat shock ( 196) 395 87.2 2e-17
NP_001876 (OMIM: 123590,608810,613763,613869,61518 ( 175) 384 84.9 8.2e-17
NP_001276737 (OMIM: 123590,608810,613763,613869,61 ( 175) 384 84.9 8.2e-17
NP_001276736 (OMIM: 123590,608810,613763,613869,61 ( 175) 384 84.9 8.2e-17
XP_011540910 (OMIM: 123590,608810,613763,613869,61 ( 175) 384 84.9 8.2e-17
NP_000385 (OMIM: 123580,604219) alpha-crystallin A ( 173) 360 80.2 2.2e-15
NP_001317308 (OMIM: 123590,608810,613763,613869,61 ( 108) 345 77.0 1.2e-14
NP_653218 (OMIM: 610695) heat shock protein beta-6 ( 160) 320 72.2 5.2e-13
XP_005261150 (OMIM: 123580,604219) PREDICTED: alph ( 136) 313 70.7 1.2e-12
NP_001532 (OMIM: 602179) heat shock protein beta-2 ( 182) 309 70.0 2.6e-12
NP_006299 (OMIM: 604624,613376) heat shock protein ( 150) 224 53.1 2.7e-07
XP_011539552 (OMIM: 610692) PREDICTED: heat shock ( 262) 172 42.9 0.00054
NP_055239 (OMIM: 610692) heat shock protein beta-7 ( 170) 168 42.0 0.00068
XP_011539551 (OMIM: 610692) PREDICTED: heat shock ( 263) 169 42.3 0.00082
>>NP_001531 (OMIM: 602195,606595,608634) heat shock prot (205 aa)
initn: 1405 init1: 1405 opt: 1405 Z-score: 1518.8 bits: 288.0 E(85289): 7.4e-78
Smith-Waterman score: 1405; 100.0% identity (100.0% similar) in 205 aa overlap (1-205:1-205)
10 20 30 40 50 60
pF1KB6 MTERRVPFSLLRGPSWDPFRDWYPHSRLFDQAFGLPRLPEEWSQWLGGSSWPGYVRPLPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MTERRVPFSLLRGPSWDPFRDWYPHSRLFDQAFGLPRLPEEWSQWLGGSSWPGYVRPLPP
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB6 AAIESPAVAAPAYSRALSRQLSSGVSEIRHTADRWRVSLDVNHFAPDELTVKTKDGVVEI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AAIESPAVAAPAYSRALSRQLSSGVSEIRHTADRWRVSLDVNHFAPDELTVKTKDGVVEI
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB6 TGKHEERQDEHGYISRCFTRKYTLPPGVDPTQVSSSLSPEGTLTVEAPMPKLATQSNEIT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TGKHEERQDEHGYISRCFTRKYTLPPGVDPTQVSSSLSPEGTLTVEAPMPKLATQSNEIT
130 140 150 160 170 180
190 200
pF1KB6 IPVTFESRAQLGGPEAAKSDETAAK
:::::::::::::::::::::::::
NP_001 IPVTFESRAQLGGPEAAKSDETAAK
190 200
>>NP_055180 (OMIM: 158590,608014,608673) heat shock prot (196 aa)
initn: 441 init1: 303 opt: 395 Z-score: 433.9 bits: 87.2 E(85289): 2e-17
Smith-Waterman score: 405; 39.6% identity (62.0% similar) in 187 aa overlap (1-174:1-176)
10 20 30 40 50
pF1KB6 MTERRVPFSLLRGPSW---DPFRDWYPHSRLFDQAFGLPRLPEE----WSQWLG---GSS
:.. ..::: . :: ::::: :::.:..::. .:.. : .: .:.
NP_055 MADGQMPFSC-HYPSRLRRDPFRDSPLSSRLLDDGFGMDPFPDDLTASWPDWALPRLSSA
10 20 30 40 50
60 70 80 90 100
pF1KB6 WPGYVRP--LPPAAIESPAVAAPAYSRALSRQLSSGVSEIRHTADRWRVSLDVNHFAPDE
::: .: .: . . ..:: .: . .. :.: ..:. : :.:
NP_055 WPGTLRSGMVPRGPTATARFGVPAEGR----------TPPPFPGEPWKVCVNVHSFKPEE
60 70 80 90 100
110 120 130 140 150 160
pF1KB6 LTVKTKDGVVEITGKHEERQDEHGYISRCFTRKYTLPPGVDPTQVSSSLSPEGTLTVEAP
: :::::: ::..:::::.:.: : .:. ::.: :: :::. : .:::::: : .:::
NP_055 LMVKTKDGYVEVSGKHEEKQQEGGIVSKNFTKKIQLPAEVDPVTVFASLSPEGLLIIEAP
110 120 130 140 150 160
170 180 190 200
pF1KB6 -MPKLATQSNEITIPVTFESRAQLGGPEAAKSDETAAK
.: .:
NP_055 QVPPYSTFGESSFNNELPQDSQEVTCT
170 180 190
>>NP_001876 (OMIM: 123590,608810,613763,613869,615184) a (175 aa)
initn: 420 init1: 349 opt: 384 Z-score: 422.8 bits: 84.9 E(85289): 8.2e-17
Smith-Waterman score: 417; 44.4% identity (64.3% similar) in 171 aa overlap (18-188:13-166)
10 20 30 40 50 60
pF1KB6 MTERRVPFSLLRGPSWDPFRDWYPHSRLFDQAFGLPRLPEEWSQWLGGSSWPGYVRPLPP
:: .. :::::: :: : . . : : :.::
NP_001 MDIAIHHPWIRRPFFPFHSPSRLFDQFFGEHLLESDLFP-TSTSLSPFYLRP---
10 20 30 40 50
70 80 90 100 110 120
pF1KB6 AAIESPAVAAPAYSRALSRQLSSGVSEIRHTADRWRVSLDVNHFAPDELTVKTKDGVVEI
:.. :: : ...:.::.: ::. :.:::.::.:.:: ::. :.:.
NP_001 ----------PSFLRAPS-WFDTGLSEMRLEKDRFSVNLDVKHFSPEELKVKVLGDVIEV
60 70 80 90 100
130 140 150 160 170 180
pF1KB6 TGKHEERQDEHGYISRCFTRKYTLPPGVDPTQVSSSLSPEGTLTVEAPMPKLATQSNEIT
:::::::::::.::: : ::: .: ::: ..:::: .:.:::..: ... . : :
NP_001 HGKHEERQDEHGFISREFHRKYRIPADVDPLTITSSLSSDGVLTVNGPRKQVS--GPERT
110 120 130 140 150
190 200
pF1KB6 IPVTFESRAQLGGPEAAKSDETAAK
::.: : .
NP_001 IPITREEKPAVTAAPKK
160 170
>>NP_001276737 (OMIM: 123590,608810,613763,613869,615184 (175 aa)
initn: 420 init1: 349 opt: 384 Z-score: 422.8 bits: 84.9 E(85289): 8.2e-17
Smith-Waterman score: 417; 44.4% identity (64.3% similar) in 171 aa overlap (18-188:13-166)
10 20 30 40 50 60
pF1KB6 MTERRVPFSLLRGPSWDPFRDWYPHSRLFDQAFGLPRLPEEWSQWLGGSSWPGYVRPLPP
:: .. :::::: :: : . . : : :.::
NP_001 MDIAIHHPWIRRPFFPFHSPSRLFDQFFGEHLLESDLFP-TSTSLSPFYLRP---
10 20 30 40 50
70 80 90 100 110 120
pF1KB6 AAIESPAVAAPAYSRALSRQLSSGVSEIRHTADRWRVSLDVNHFAPDELTVKTKDGVVEI
:.. :: : ...:.::.: ::. :.:::.::.:.:: ::. :.:.
NP_001 ----------PSFLRAPS-WFDTGLSEMRLEKDRFSVNLDVKHFSPEELKVKVLGDVIEV
60 70 80 90 100
130 140 150 160 170 180
pF1KB6 TGKHEERQDEHGYISRCFTRKYTLPPGVDPTQVSSSLSPEGTLTVEAPMPKLATQSNEIT
:::::::::::.::: : ::: .: ::: ..:::: .:.:::..: ... . : :
NP_001 HGKHEERQDEHGFISREFHRKYRIPADVDPLTITSSLSSDGVLTVNGPRKQVS--GPERT
110 120 130 140 150
190 200
pF1KB6 IPVTFESRAQLGGPEAAKSDETAAK
::.: : .
NP_001 IPITREEKPAVTAAPKK
160 170
>>NP_001276736 (OMIM: 123590,608810,613763,613869,615184 (175 aa)
initn: 420 init1: 349 opt: 384 Z-score: 422.8 bits: 84.9 E(85289): 8.2e-17
Smith-Waterman score: 417; 44.4% identity (64.3% similar) in 171 aa overlap (18-188:13-166)
10 20 30 40 50 60
pF1KB6 MTERRVPFSLLRGPSWDPFRDWYPHSRLFDQAFGLPRLPEEWSQWLGGSSWPGYVRPLPP
:: .. :::::: :: : . . : : :.::
NP_001 MDIAIHHPWIRRPFFPFHSPSRLFDQFFGEHLLESDLFP-TSTSLSPFYLRP---
10 20 30 40 50
70 80 90 100 110 120
pF1KB6 AAIESPAVAAPAYSRALSRQLSSGVSEIRHTADRWRVSLDVNHFAPDELTVKTKDGVVEI
:.. :: : ...:.::.: ::. :.:::.::.:.:: ::. :.:.
NP_001 ----------PSFLRAPS-WFDTGLSEMRLEKDRFSVNLDVKHFSPEELKVKVLGDVIEV
60 70 80 90 100
130 140 150 160 170 180
pF1KB6 TGKHEERQDEHGYISRCFTRKYTLPPGVDPTQVSSSLSPEGTLTVEAPMPKLATQSNEIT
:::::::::::.::: : ::: .: ::: ..:::: .:.:::..: ... . : :
NP_001 HGKHEERQDEHGFISREFHRKYRIPADVDPLTITSSLSSDGVLTVNGPRKQVS--GPERT
110 120 130 140 150
190 200
pF1KB6 IPVTFESRAQLGGPEAAKSDETAAK
::.: : .
NP_001 IPITREEKPAVTAAPKK
160 170
>>XP_011540910 (OMIM: 123590,608810,613763,613869,615184 (175 aa)
initn: 420 init1: 349 opt: 384 Z-score: 422.8 bits: 84.9 E(85289): 8.2e-17
Smith-Waterman score: 417; 44.4% identity (64.3% similar) in 171 aa overlap (18-188:13-166)
10 20 30 40 50 60
pF1KB6 MTERRVPFSLLRGPSWDPFRDWYPHSRLFDQAFGLPRLPEEWSQWLGGSSWPGYVRPLPP
:: .. :::::: :: : . . : : :.::
XP_011 MDIAIHHPWIRRPFFPFHSPSRLFDQFFGEHLLESDLFP-TSTSLSPFYLRP---
10 20 30 40 50
70 80 90 100 110 120
pF1KB6 AAIESPAVAAPAYSRALSRQLSSGVSEIRHTADRWRVSLDVNHFAPDELTVKTKDGVVEI
:.. :: : ...:.::.: ::. :.:::.::.:.:: ::. :.:.
XP_011 ----------PSFLRAPS-WFDTGLSEMRLEKDRFSVNLDVKHFSPEELKVKVLGDVIEV
60 70 80 90 100
130 140 150 160 170 180
pF1KB6 TGKHEERQDEHGYISRCFTRKYTLPPGVDPTQVSSSLSPEGTLTVEAPMPKLATQSNEIT
:::::::::::.::: : ::: .: ::: ..:::: .:.:::..: ... . : :
XP_011 HGKHEERQDEHGFISREFHRKYRIPADVDPLTITSSLSSDGVLTVNGPRKQVS--GPERT
110 120 130 140 150
190 200
pF1KB6 IPVTFESRAQLGGPEAAKSDETAAK
::.: : .
XP_011 IPITREEKPAVTAAPKK
160 170
>>NP_000385 (OMIM: 123580,604219) alpha-crystallin A cha (173 aa)
initn: 382 init1: 327 opt: 360 Z-score: 397.1 bits: 80.2 E(85289): 2.2e-15
Smith-Waterman score: 364; 41.4% identity (60.9% similar) in 174 aa overlap (18-188:16-166)
10 20 30 40 50 60
pF1KB6 MTERRVPFSLLRGPSWDPFRDWYPHSRLFDQAFGLPRLPEEWSQWLGGSSWPGYVRPLPP
:: :: :::::: :: . . .:...
NP_000 MDVTIQHPWFKRTLGPF---YP-SRLFDQFFGEGLFEYDLLPFLSST-----------
10 20 30 40
70 80 90 100 110
pF1KB6 AAIESPAVAAPAYSRALSRQ-LSSGVSEIRHTADRWRVSLDVNHFAPDELTVKTKDGVVE
.: : ..: : :.::.::.: :.. . :::.::.:..::::..: ::
NP_000 --------ISPYYRQSLFRTVLDSGISEVRSDRDKFVIFLDVKHFSPEDLTVKVQDDFVE
50 60 70 80 90
120 130 140 150 160 170
pF1KB6 ITGKHEERQDEHGYISRCFTRKYTLPPGVDPTQVSSSLSPEGTLTVEAPMPK--LATQSN
: :::.::::.:::::: : :.: :: .:: . .: ::: .: :: .: . : .
NP_000 IHGKHNERQDDHGYISREFHRRYRLPSNVDQSALSCSLSADGMLTFCGPKIQTGLDATHA
100 110 120 130 140 150
180 190 200
pF1KB6 EITIPVTFESRAQLGGPEAAKSDETAAK
: .:::. : .
NP_000 ERAIPVSREEKPTSAPSS
160 170
>>NP_001317308 (OMIM: 123590,608810,613763,613869,615184 (108 aa)
initn: 341 init1: 321 opt: 345 Z-score: 383.8 bits: 77.0 E(85289): 1.2e-14
Smith-Waterman score: 345; 52.5% identity (75.2% similar) in 101 aa overlap (88-188:1-99)
60 70 80 90 100 110
pF1KB6 LPPAAIESPAVAAPAYSRALSRQLSSGVSEIRHTADRWRVSLDVNHFAPDELTVKTKDGV
.: ::. :.:::.::.:.:: ::. :
NP_001 MRLEKDRFSVNLDVKHFSPEELKVKVLGDV
10 20 30
120 130 140 150 160 170
pF1KB6 VEITGKHEERQDEHGYISRCFTRKYTLPPGVDPTQVSSSLSPEGTLTVEAPMPKLATQSN
.:. :::::::::::.::: : ::: .: ::: ..:::: .:.:::..: ... .
NP_001 IEVHGKHEERQDEHGFISREFHRKYRIPADVDPLTITSSLSSDGVLTVNGPRKQVS--GP
40 50 60 70 80
180 190 200
pF1KB6 EITIPVTFESRAQLGGPEAAKSDETAAK
: :::.: : .
NP_001 ERTIPITREEKPAVTAAPKK
90 100
>>NP_653218 (OMIM: 610695) heat shock protein beta-6 [Ho (160 aa)
initn: 367 init1: 289 opt: 320 Z-score: 354.6 bits: 72.2 E(85289): 5.2e-13
Smith-Waterman score: 330; 38.4% identity (58.5% similar) in 159 aa overlap (14-167:9-146)
10 20 30 40 50
pF1KB6 MTERRVPFSLLRGPSW-----DPFRDWYPHSRLFDQAFGLPRLPEEWSQWLGGSSWPGYV
::: :. .::::: :: : : . . : :.
NP_653 MEIPVPVQPSWLRRASAPLPGLSAPGRLFDQRFGEGLLEAELAALCPTTLAPYYL
10 20 30 40 50
60 70 80 90 100 110
pF1KB6 RPLPPAAIESPAVAAPAYSRALSRQLSSGVSEIRHTADRWRVSLDVNHFAPDELTVKTKD
: .:.:: : :... .. : :::.::.:.:..::.
NP_653 R--------APSVALP-------------VAQVPTDPGHFSVLLDVKHFSPEEIAVKVVG
60 70 80 90
120 130 140 150 160 170
pF1KB6 GVVEITGKHEERQDEHGYISRCFTRKYTLPPGVDPTQVSSSLSPEGTLTVEAPMPKLATQ
::. ..:::: ::::...: : :.: :::::::. :.:.:::::.:...:
NP_653 EHVEVHARHEERPDEHGFVAREFHRRYRLPPGVDPAAVTSALSPEGVLSIQAAPASAQAP
100 110 120 130 140 150
180 190 200
pF1KB6 SNEITIPVTFESRAQLGGPEAAKSDETAAK
NP_653 PPAAAK
160
>>XP_005261150 (OMIM: 123580,604219) PREDICTED: alpha-cr (136 aa)
initn: 312 init1: 282 opt: 313 Z-score: 348.0 bits: 70.7 E(85289): 1.2e-12
Smith-Waterman score: 313; 48.1% identity (71.2% similar) in 104 aa overlap (87-188:26-129)
60 70 80 90 100 110
pF1KB6 PLPPAAIESPAVAAPAYSRALSRQLSSGVSEIRHTADRWRVSLDVNHFAPDELTVKTKDG
..: :.. . :::.::.:..::::..:
XP_005 MPVCPGDSHRPPKALPHLVCGRRGRQVRSDRDKFVIFLDVKHFSPEDLTVKVQDD
10 20 30 40 50
120 130 140 150 160 170
pF1KB6 VVEITGKHEERQDEHGYISRCFTRKYTLPPGVDPTQVSSSLSPEGTLTVEAPMPK--LAT
::: :::.::::.:::::: : :.: :: .:: . .: ::: .: :: .: . : .
XP_005 FVEIHGKHNERQDDHGYISREFHRRYRLPSNVDQSALSCSLSADGMLTFCGPKIQTGLDA
60 70 80 90 100 110
180 190 200
pF1KB6 QSNEITIPVTFESRAQLGGPEAAKSDETAAK
: .:::. : .
XP_005 THAERAIPVSREEKPTSAPSS
120 130
205 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 13:02:14 2016 done: Fri Nov 4 13:02:15 2016
Total Scan time: 5.960 Total Display time: -0.010
Function used was FASTA [36.3.4 Apr, 2011]