Result of FASTA (ccds) for
pFN21AE2179
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE2179, 281 aa
1>>>pF1KE2179 281 - 281 aa - 281 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.7188+/-0.000898; mu= 12.6928+/- 0.054
mean_var=65.9572+/-12.904, 0's: 0 Z-trim(105.6): 39 B-trim: 2 in 1/49
Lambda= 0.157922
statistics sampled from 8465 (8491) to 8465 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.642), E-opt: 0.2 (0.261), width: 16
Scan time: 1.910
The best scores are: opt bits E(32554)
CCDS3219.1 TNFSF10 gene_id:8743|Hs108|chr3 ( 281) 1876 436.2 1.2e-122
CCDS54680.1 TNFSF10 gene_id:8743|Hs108|chr3 ( 101) 622 150.4 5e-37
CCDS9384.1 TNFSF11 gene_id:8600|Hs108|chr13 ( 317) 318 81.3 9.9e-16
CCDS9385.1 TNFSF11 gene_id:8600|Hs108|chr13 ( 244) 296 76.2 2.5e-14
>>CCDS3219.1 TNFSF10 gene_id:8743|Hs108|chr3 (281 aa)
initn: 1876 init1: 1876 opt: 1876 Z-score: 2315.1 bits: 436.2 E(32554): 1.2e-122
Smith-Waterman score: 1876; 100.0% identity (100.0% similar) in 281 aa overlap (1-281:1-281)
10 20 30 40 50 60
pF1KE2 MAMMEVQGGPSLGQTCVLIVIFTVLLQSLCVAVTYVYFTNELKQMQDKYSKSGIACFLKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS32 MAMMEVQGGPSLGQTCVLIVIFTVLLQSLCVAVTYVYFTNELKQMQDKYSKSGIACFLKE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 DDSYWDPNDEESMNSPCWQVKWQLRQLVRKMILRTSEETISTVQEKQQNISPLVRERGPQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS32 DDSYWDPNDEESMNSPCWQVKWQLRQLVRKMILRTSEETISTVQEKQQNISPLVRERGPQ
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 RVAAHITGTRGRSNTLSSPNSKNEKALGRKINSWESSRSGHSFLSNLHLRNGELVIHEKG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS32 RVAAHITGTRGRSNTLSSPNSKNEKALGRKINSWESSRSGHSFLSNLHLRNGELVIHEKG
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE2 FYYIYSQTYFRFQEEIKENTKNDKQMVQYIYKYTSYPDPILLMKSARNSCWSKDAEYGLY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS32 FYYIYSQTYFRFQEEIKENTKNDKQMVQYIYKYTSYPDPILLMKSARNSCWSKDAEYGLY
190 200 210 220 230 240
250 260 270 280
pF1KE2 SIYQGGIFELKENDRIFVSVTNEHLIDMDHEASFFGAFLVG
:::::::::::::::::::::::::::::::::::::::::
CCDS32 SIYQGGIFELKENDRIFVSVTNEHLIDMDHEASFFGAFLVG
250 260 270 280
>>CCDS54680.1 TNFSF10 gene_id:8743|Hs108|chr3 (101 aa)
initn: 675 init1: 622 opt: 622 Z-score: 778.2 bits: 150.4 E(32554): 5e-37
Smith-Waterman score: 622; 100.0% identity (100.0% similar) in 90 aa overlap (1-90:1-90)
10 20 30 40 50 60
pF1KE2 MAMMEVQGGPSLGQTCVLIVIFTVLLQSLCVAVTYVYFTNELKQMQDKYSKSGIACFLKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 MAMMEVQGGPSLGQTCVLIVIFTVLLQSLCVAVTYVYFTNELKQMQDKYSKSGIACFLKE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 DDSYWDPNDEESMNSPCWQVKWQLRQLVRKMILRTSEETISTVQEKQQNISPLVRERGPQ
::::::::::::::::::::::::::::::
CCDS54 DDSYWDPNDEESMNSPCWQVKWQLRQLVRKTPRMKRLWAAK
70 80 90 100
>>CCDS9384.1 TNFSF11 gene_id:8600|Hs108|chr13 (317 aa)
initn: 269 init1: 179 opt: 318 Z-score: 395.9 bits: 81.3 E(32554): 9.9e-16
Smith-Waterman score: 328; 25.4% identity (58.5% similar) in 284 aa overlap (10-280:42-313)
10 20 30
pF1KE2 MAMMEVQGGPSLGQTCVLIVIFTVLLQSLCVAVTYVYFT
:. ... . .. : : .: .. . ::
CCDS93 LRGSEEMGGGPGAPHEGPLHAPPPPAPHQPPAASRSMFVALLGLGLGQVVCSVALFFYFR
20 30 40 50 60 70
40 50 60 70 80 90
pF1KE2 NELKQMQDKYSKSGIACF-----LKEDDSYWDPN----DEESMNSPCWQVKWQLRQLVRK
.. .. :..: :. :.:. .. : . : . . . : ..: .. :.:
CCDS93 AQMDP--NRISEDGTHCIYRILRLHENADFQDTTLESQDTKLIPDSCRRIKQAFQGAVQK
80 90 100 110 120
100 110 120 130 140
pF1KE2 MILRTSEETISTVQEKQQNISPL---VRERGPQRVAAHITGTRGRSNTLSSPNSKNEKAL
. . ... . . : : : . . ::.: :. . :..... .:
CCDS93 ELQHIVGSQHIRAEKAMVDGSWLDLAKRSKLEAQPFAHLT-----INATDIPSGSHKVSL
130 140 150 160 170 180
150 160 170 180 190 200
pF1KE2 GRKINSWESSRSGHSFLSNLHLRNGELVIHEKGFYYIYSQTYFRFQEEIKENTKNDKQMV
.:: .: : . .::. . ::.:.... ::::.:.. :: .: . . . :..
CCDS93 ----SSWYHDR-GWAKISNMTFSNGKLIVNQDGFYYLYANICFRHHETSGDLATEYLQLM
190 200 210 220 230
210 220 230 240 250 260
pF1KE2 QYIYKYT-SYPDPILLMKSARNSCWSKDAEYGLYSIYQGGIFELKENDRIFVSVTNEHLI
:. : . . :. :::.. .. :: ..:. .::: ::.:.:. ...: . :.: :.
CCDS93 VYVTKTSIKIPSSHTLMKGGSTKYWSGNSEFHFYSINVGGFFKLRSGEEISIEVSNPSLL
240 250 260 270 280 290
270 280
pF1KE2 DMDHEASFFGAFLVG
: :..:..:::: :
CCDS93 DPDQDATYFGAFKVRDID
300 310
>>CCDS9385.1 TNFSF11 gene_id:8600|Hs108|chr13 (244 aa)
initn: 269 init1: 179 opt: 296 Z-score: 370.6 bits: 76.2 E(32554): 2.5e-14
Smith-Waterman score: 302; 26.7% identity (59.5% similar) in 247 aa overlap (47-280:4-240)
20 30 40 50 60
pF1KE2 VLIVIFTVLLQSLCVAVTYVYFTNELKQMQDKYSKSGIACF-----LKEDDSYWDPN---
.. :..: :. :.:. .. : .
CCDS93 MDPNRISEDGTHCIYRILRLHENADFQDTTLES
10 20 30
70 80 90 100 110 120
pF1KE2 -DEESMNSPCWQVKWQLRQLVRKMILRTSEETISTVQEKQQNISPL---VRERGPQRVAA
: . . . : ..: .. :.: . . ... . . : : : . . :
CCDS93 QDTKLIPDSCRRIKQAFQGAVQKELQHIVGSQHIRAEKAMVDGSWLDLAKRSKLEAQPFA
40 50 60 70 80 90
130 140 150 160 170 180
pF1KE2 HITGTRGRSNTLSSPNSKNEKALGRKINSWESSRSGHSFLSNLHLRNGELVIHEKGFYYI
:.: :. . :..... .: .:: .: : . .::. . ::.:.... ::::.
CCDS93 HLT-----INATDIPSGSHKVSL----SSWYHDR-GWAKISNMTFSNGKLIVNQDGFYYL
100 110 120 130 140
190 200 210 220 230 240
pF1KE2 YSQTYFRFQEEIKENTKNDKQMVQYIYKYT-SYPDPILLMKSARNSCWSKDAEYGLYSIY
:.. :: .: . . . :.. :. : . . :. :::.. .. :: ..:. .:::
CCDS93 YANICFRHHETSGDLATEYLQLMVYVTKTSIKIPSSHTLMKGGSTKYWSGNSEFHFYSIN
150 160 170 180 190 200
250 260 270 280
pF1KE2 QGGIFELKENDRIFVSVTNEHLIDMDHEASFFGAFLVG
::.:.:. ...: . :.: :.: :..:..:::: :
CCDS93 VGGFFKLRSGEEISIEVSNPSLLDPDQDATYFGAFKVRDID
210 220 230 240
281 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Mon Nov 7 00:03:15 2016 done: Mon Nov 7 00:03:16 2016
Total Scan time: 1.910 Total Display time: -0.010
Function used was FASTA [36.3.4 Apr, 2011]